thioacetamide has been researched along with lasiocarpine* in 1 studies
1 other study(ies) available for thioacetamide and lasiocarpine
| Article | Year |
|---|---|
Effect of calorie restriction on the fate of hyperplastic liver nodules induced by concurrent administration of lasiocarpine and thioacetamide.
1 Hyperplastic liver nodules were induced in F-344 rats by concurrent administration of lasiocarpine (50 ppm in diet) and thioacetamide (50 mg/kg body weight twice weekly) for 15 weeks. 2 The effect of carbohydrate calorie and total calorie restriction on the fate of hyperplastic liver nodules was examined. 3 The incidence of hepatocellular carcinoma was the same in all groups of rats irrespective of the magnitude of carbohydrate calorie restriction and 50% total calorie restriction. 4 These studies demonstrate that carbohydrate or total calorie restriction has no effect on the progression of hyperplastic nodules to hepatocellular carcinoma. Topics: Acetamides; Animals; Body Weight; Carcinogens; Diet; Dietary Carbohydrates; Energy Intake; Hyperplasia; Liver; Liver Neoplasms; Male; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Thioacetamide | 1983 |