thienopyrimidine has been researched along with 4-methoxybenzylamine* in 1 studies
1 other study(ies) available for thienopyrimidine and 4-methoxybenzylamine
Article | Year |
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Synthesis of novel dihydropyridothienopyrimidin-4,9-dione derivatives.
A novel molecular scaffold, dihydropyridothienopyrimidin-4,9-dione, was synthesized from benzylamine or p-methoxybenzylamine in six steps involving successive ring closure to form a fused ring system composed of dihydropyridone, thiophene and pyrimidone. The pharmacological versatility of the dihydropyridothenopyrimidin-4,9-dione scaffold was demonstrated by inhibitory activity against metabotropic glutamate receptor subtype 1 (mGluR1), which shows that the title compounds can serve as an interesting scaffold for the discovery of potential bioactive molecules for the treatment of human diseases. Topics: Benzylamines; Humans; Molecular Structure; Pyrimidines; Receptors, Metabotropic Glutamate | 2015 |