thienopyridine and malonamide

thienopyridine has been researched along with malonamide* in 1 studies

Other Studies

1 other study(ies) available for thienopyridine and malonamide

Article	Year
N3-arylmalonamides: a new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases. Bioorganic & medicinal chemistry letters, 2009, Dec-15, Volume: 19, Issue:24 A family of thieno[3,2-b]pyridine based small molecule inhibitors of c-Met and VEGFR2 were designed based on lead structure 2. These compounds were shown to have IC(50) values in the low nanomolar range in vitro and were efficacious in human tumor xenograft models in mice in vivo. Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Malonates; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Vascular Endothelial Growth Factor Receptor-2	2009

Article

Year

N3-arylmalonamides: a new series of thieno[3,2-b]pyridine based inhibitors of c-Met and VEGFR2 tyrosine kinases.

Bioorganic & medicinal chemistry letters, 2009, Dec-15, Volume: 19, Issue:24

A family of thieno[3,2-b]pyridine based small molecule inhibitors of c-Met and VEGFR2 were designed based on lead structure 2. These compounds were shown to have IC(50) values in the low nanomolar range in vitro and were efficacious in human tumor xenograft models in mice in vivo.

Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Malonates; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Vascular Endothelial Growth Factor Receptor-2

2009