thiazolyl blue has been researched along with thiazoles in 4393 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (1.66) | 18.7374 |
| 1990's | 654 (14.89) | 18.2507 |
| 2000's | 2229 (50.74) | 29.6817 |
| 2010's | 1365 (31.07) | 24.3611 |
| 2020's | 72 (1.64) | 2.80 |
| Authors | Studies |
|---|---|
| Boethling, RS; Weaver, TL | 1 |
| Acosta, D; Gabaldon, D; Grant, RL; Yao, C | 1 |
| Chen, CF; Gu, XS; Yan, WX; Yan, ZQ | 1 |
| Cedillo-Rivera, R; Muñoz, O; Ramírez, A | 1 |
| Funahara, Y; Sumiyoshi, A; Tamaki, T; Tanabe, S; Wada, Y | 1 |
| Brooks, JC; Brooks, MH; Carmichael, SW | 1 |
| Wu, JZ | 1 |
| Tashiro, T | 1 |
| Black, P; Hand, CM; Jordan, JP; Markowitz, RS | 1 |
| Hironao, T; Kajikawa, T; Kawamura, H; Tajima, T | 1 |
| Metzgar, RS; Petrow, V; Selvan, RS | 1 |
| Di Fiore, PP; Kasprzyk, PG; King, CR; Song, SU | 1 |
| Belov, L; Davey, MW; Davey, RA; Kidman, AD; Marks, DC | 1 |
| Fukuda, H; Yamaji, H | 1 |
| Ben Trivedi, A; Doi, E; Kitabatake, N | 1 |
| Emborg, C; Kierulff, JV; Rexen, P | 1 |
| Kato, K; Koga, N; Maeda, S; Oka, M; Saito, T | 1 |
| al-Rubeai, MA; Evans, NH; Lambe, CA; Musgrave, SC; Spier, RE; Walker, AG | 1 |
| Berridge, MV; Tan, AS | 2 |
| Azzi, S; Guillemin, F; Lignon, D; Merlin, JL; Ramacci, C; Zeghari, N | 1 |
| Janjic, D; Wollheim, CB | 1 |
| Kajio, T; Kato, K; Kawahara, K | 1 |
| Jiao, H; Miura, K; Ohe, Y; Saijo, N; Shen, W; Tamura, T | 1 |
| Lambert, E; Rees, JK; Twentyman, PR | 1 |
| Hertzog, PJ; Johns, TG; Loveland, BE; Mackay, IR; Vaillant, F; Wang, ZX | 1 |
| Hotta, T; Iwahashi, M; Iwakura, S; Noguchi, K; Tamai, M; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H | 1 |
| Alomar, Y; Levade, T; Nègre-Salvayre, A; Salvayre, R; Valdiguié, P | 1 |
| Bleehen, NM; Ramsay, J; Ward, R | 1 |
| Bonnefoi, MS | 1 |
| Colangelo, D; Connors, KM; Guo, HY; Hoffman, RM; Silvestro, L | 1 |
| Dressen, F; Hanisch, FG; Uhlenbruck, G | 1 |
| Barnes, PJ; Hirst, SJ; Twort, CH | 1 |
| Ezell, EL; Jackson, GR; Perez-Polo, JR; Post, JF; Werrbach-Perez, K | 1 |
| Atzori, L; Cotgreave, I; Grafström, RC; Liu, Y | 1 |
| Fujimaru, J; Hirabayashi, K; Ogura, M; Takeda, Y; Tomiyoshi, Y; Wada, Y; Yoshida, S | 1 |
| Jiao, H; Miura, K; Ohe, Y; Saijo, N; Soejima, Y; Tamura, T | 1 |
| Bergamini, A; Caliò, R; Capozzi, M; Mannella, E; Perno, CF; Rocchi, G; Salanitro, A | 1 |
| Cloarec, D; Combre, A; Foultier, MT; Patrice, T; Vonarx-Coinsmann, V; Xu, XN | 1 |
| Isshiki, K; Kubota, H; Nishimoto, F; Usuda, M; Yamashoji, S | 1 |
| Pralong, WF; Rutter, GA; Wollheim, CB | 1 |
| Siedlar, M; Uracz, W; Zembala, M | 1 |
| Schmidt, JA; von Recum, AF | 1 |
| Franz, B; Kirchhoff, H; Maass, C; Mühlradt, PF; Quentmeier, H; Runge, M; Schmidt, R | 1 |
| Berger, MR; Sobottka, SB | 1 |
| Bloomer, WD; Prezioso, JA; Wang, N | 1 |
| Andersen, RJ; Emerman, JT; Stingl, J | 1 |
| Greve, EL; Nuyts, RM; Pels, E | 1 |
| Lohmeyer, M; Workman, P | 2 |
| Jiao, H; Ohe, Y; Saijo, N; Soejima, Y | 1 |
| Barbenel, JC; Courtney, JM; Grant, MH; Smith, MD | 1 |
| Castell, JV; Gómez-Lechón, MJ; Jover, R; Ponsoda, X | 1 |
| Gautheron, PD; Laszek, MA; Sina, JF; Ward, GJ | 1 |
| Chavan, S; Chitnis, M; Parekh, H | 1 |
| Guo, XB; Kawanishi, T; Ohno, Y; Sunouchi, M; Takanaka, A | 1 |
| Hayashihara, K; Hino, M; Kobayashi, K; Nakahiro, K; Niitani, H; Takemoto, T; Wasai, S | 1 |
| Burger, CJ; Elgert, KD; Walker, TM; Yurochko, AD | 1 |
| Bohnet, S; Carstensen, O; Hacker, J; Kreft, B; Marre, R; Straube, E | 1 |
| Beelen, RH; Broekhoven, MG; Langenhuijsen, MM; Ossenkoppele, GJ; van de Loosdrecht, AA | 2 |
| Bafaloukos, D; Photiou, A; Retsas, S; Sheikh, MN | 1 |
| Berger, MR; Galeano, A; Keppler, BK | 1 |
| Hisatsugu, T; Katano, M; Matsunaga, H; Morita, H; Oogushi, K; Sunaga, T; Yamamoto, H | 1 |
| Darling, JL; Hoffmann, O; Kraemer, HP; Nikkhah, G; Schachenmayr, W; Schönmayr, R; Tonn, JC | 2 |
| Huet, O; Julien, R; Petit, JM; Ratinaud, MH | 1 |
| de Kloet, ER; Heimans, JJ; Langeveld, CH; Stoof, JC; Sutanto, W; van Waas, MP; Wolbers, JG | 1 |
| Akita, H; Fijita, H; Haneda, H; Katabami, M; Kawakami, Y; Kuzumaki, N; Miyamoto, H | 1 |
| Jackson, GR; Morgan, BC; Perez-Polo, JR; Werrbach-Perez, K | 1 |
| Baba, M; Shigeta, S; Takeuchi, H | 1 |
| Hählen, K; Huismans, DR; Loonen, AH; Pieters, R; van der Does-van den Berg, A; van Wering, ER; Veerman, AJ | 1 |
| Mehta, K; Rao, UR; Subrahmanyam, D; Vickery, AC | 1 |
| Advani, S; Chavan, S; Chitnis, M; Hegde, U; Juvekar, A | 1 |
| Berg, K; Hansen, MB; Ross, C | 1 |
| Alken, P; Fajta, S; Keilhauer, G; Mickisch, G; Schlick, E; Tschada, R | 1 |
| Kalden, JR; Oez, S; Platzer, E; Welte, K | 1 |
| Senderoff, RI; Smith, DR; Sokoloski, TD; Weber, PA | 1 |
| Heegaard, NH | 1 |
| Kato, M; Ohashi, K; Saji, F; Tanizawa, O; Wakimoto, A | 1 |
| Asanuma, F; Fujinaga, S; Kawamura, E; Kubota, T; Kurokawa, T; Lee, KE; Suzuki, T; Suzuki, Y; Yamada, T; Yamada, Y | 1 |
| Azri, S; Brendel, K; Gandolfi, AJ; Mata, HP; Reid, LL | 1 |
| Baba, H; Korenaga, D; Maehara, Y; Okamura, T; Saito, A; Sugimachi, K | 1 |
| Isobe, K; Nakashima, I; Satta, T; Takagi, H; Yamauchi, M | 1 |
| Okada, H; Urabe, I; Yomo, T | 2 |
| Hamajima, N; Inokuchi, K; Kato, K; Kondo, T; Takagi, H; Yamauchi, M | 1 |
| Furukawa, T; Ishibiki, K; Kase, S; Kitajima, M; Kodaira, S; Kubota, T; Kuo, TH; Nishibori, H; Saikawa, Y; Watanabe, M | 1 |
| Cheng, AL; Mitchen, J; Oberley, T; Rago, R; Wilding, G | 1 |
| Fujii, Y; Hongo, T | 1 |
| Abe, T; Ohno, M | 1 |
| Lefkowitz, DL; Lefkowitz, SS; Mills, KC; Morgan, CD | 1 |
| Ansorge, S; Bank, U; Reinhold, D | 1 |
| Ambrosius, H; Blechschmidt, I; Schröder, S; Weichert, H | 1 |
| Laschinski, G; Spielmann, H; Vogel, R | 1 |
| Keepers, YP; Peters, GJ; Pinedo, HM; Pizao, PE; van Ark-Otte, J; Winograd, B | 1 |
| Arii, K; Hotta, T; Iwahashi, M; Noguchi, K; Tamai, M; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H | 1 |
| Acosta, D; Hsieh, GC | 1 |
| Hefti, AF; Tullberg-Reinert, H | 1 |
| Beelen, RH; Langenhuijsen, MM; Nennie, E; Ossenkoppele, GJ; van de Loosdrecht, AA | 1 |
| Barltrop, JA; Cory, AH; Cory, JG; Owen, TC | 1 |
| Müller, MR; Twentyman, PR; Wright, KA | 1 |
| Nare, B; Prichard, RK; Smith, JM | 1 |
| Canning, PC; Kehrli, ME; Stevens, MG | 1 |
| Suto, A | 2 |
| Fujimaru, J; Ogura, M; Takeda, Y; Tomiyoshi, Y; Wada, Y; Yoshida, S | 1 |
| Endo, Y; Kimura, H; Kinoshita, K; Miyazaki, I; Ninomiya, I; Ohyama, S; Sasaki, T; Tanaka, M; Tugawa, K; Yonemura, Y | 1 |
| Glasebrook, AL; Hatfield, SM; Rodgers, GH; Roehm, NW | 1 |
| Furukawa, T; Ishibiki, K; Kase, S; Kodaira, S; Kubota, T; Suto, A; Takahara, T; Takeuchi, T; Yamaguchi, H | 1 |
| Shanafelt, AB | 1 |
| Cambridge, G; Hall, TJ; James, PR | 1 |
| Burdon, RH; Gill, V; Rice-Evans, C | 2 |
| Ishikawa, M; Kondo, T; Sato, Y; Tatematsu, A | 1 |
| Hasegawa, N; Kasugai, S; Ogura, H | 2 |
| Archer, MC; Chaulk, EJ; Giles, A; Zucker, PF | 1 |
| Boyd, MR; Monks, A; Pittman, A; Scudiero, D; Skehan, P; Vistica, DT | 1 |
| McDevitt, CA; Miller, RR | 1 |
| Sefton, MV; Uludag, H | 1 |
| Campbell, PA; Chen, CH; Newman, LS | 1 |
| Busová, B; Niks, M; Otto, M; Stefanovic, J | 1 |
| Chen, AK; Givens, KT; Kitada, S; Lee, DA; Rothschiller, J | 1 |
| de Leij, L; de Vries, EG; Hospers, GA; Meijer, C; Mulder, NH; Uges, DR | 1 |
| Chen, CF; Chen, CS; Chen, KY; Hwang, JM; Wu, CH | 1 |
| Fleischmann, WR; Kotnik, V | 1 |
| Abe, O; Asanuma, F; Ishibiki, K; Kawamura, E; Kubota, T; Suto, A; Suzuki, T; Suzuki, Y; Yamada, T; Yamada, Y | 1 |
| Dienwiebel, U; Melzig, M | 1 |
| Brendel, W; Delius, M; Gambihler, S | 1 |
| Cory, JG; Fox, JG; Koneru, PB; Lien, EJ; Matsumoto, M; Wang, PH | 1 |
| Loftis, AY; Pruett, SB | 1 |
| Broekema, GJ; Dirven, MW; Hählen, K; Heyenbrok, MW; Huismans, DR; Loonen, AH; Pieters, R; Veerman, AJ | 1 |
| Oez, S; Platzer, E; Welte, K | 1 |
| McMillan, TJ; Price, P | 1 |
| Bruno, NA; Slate, DL | 1 |
| Cassano, WF; Zaytoun, AM | 1 |
| Atkinson, T; Goward, CR; Price, CP; Scawen, MD; Scott, DA | 1 |
| Idota, C; Takagi, H; Yamauchi, M | 1 |
| Gallo, RL; Held, KD; Kochevar, IE; Mirro, J; Walsh, AA | 1 |
| Day, R; Hata, K; Heo, DS; Herberman, RB; Park, JG; Whiteside, TL | 1 |
| Duke, M; Goh, TS; Kirkpatrick, DL | 1 |
| Niks, M; Otto, M | 1 |
| Boyd, MR; Monks, A; Paull, KD; Rubinstein, LV; Scudiero, DA; Shoemaker, RH; Simon, RM; Skehan, P; Tosini, S | 1 |
| Eliason, JF; Kaufmann, F; Ramuz, H | 1 |
| Fukuchi, S; Hashimoto, M; Hayakawa, K; Kato, M; Sugano, K; Yoshida, Y | 1 |
| Ferrari, M; Fornasiero, MC; Isetta, AM | 1 |
| Diamond, RD; Levitz, SM | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Schols, D; Snoeck, R | 1 |
| Krolikowski, I; Rieger, CH; Schauer, U | 1 |
| Henin, Y; Marechal, V; Montagnier, L; Schwartz, O | 1 |
| Berg, K; Hansen, MB; Nielsen, SE | 1 |
| Baba, M; De Clercq, E; Desmyter, J; Nakashima, H; Pauwels, R; Schols, D | 1 |
| Stephens, MA; Stratford, IJ | 1 |
| Inoue, H; Ito, S; Kawai, A; Ozaki, T; Sato, J; Tanabe, G | 1 |
| Jabbar, SA; Twentyman, PR; Watson, JV | 1 |
| Ariyoshi, Y; Hida, T; Kato, T; Sugiura, T; Suyama, M; Takahashi, T; Ueda, R; Watanabe, H | 1 |
| Coley, HM; Twentyman, PR; Workman, P | 1 |
| Meunier, F; Van der Auwera, P | 1 |
| Nagakura, K; Nakamura, H; Odajima, K; Sawamura, M | 1 |
| Comley, JC; Dobinson, A; Rees, MJ; Townson, S | 1 |
| Buckley, RG; Fricker, SP | 1 |
| Fong, TA; Mosmann, TR | 1 |
| Yung, WK | 1 |
| Facci, L; Leon, A; Milani, D; Skaper, SD | 1 |
| Abe, O; Ishibiki, K; Kubota, T; Shimoyama, Y; Watanabe, M | 1 |
| Kaye, SB; Milroy, R; Plumb, JA | 1 |
| Sargent, JM; Taylor, CG | 1 |
| Latchman, DS; Norton, PM | 1 |
| Ford, CH; Richardson, VJ; Tsaltas, G | 1 |
| Borzelleca, JF; Condie, LW; Gennings, C; Lamb, RG | 1 |
| Fujita, F; Fujita, M; Inaba, H; Kusuyama, T; Sakamoto, Y; Shimozuma, K; Taguchi, T; Tanigawa, K | 1 |
| McLean, JR; Wilkinson, D | 1 |
| Bublitz, C; Lawler, CA | 1 |
| Carmichael, J; DeGraff, WG; Gamson, J; Gazdar, AF; Glatstein, E; Johnson, BE; Minna, JD; Mitchell, JB | 1 |
| Fujiwara, Y; Horiuchi, N; Minato, K; Nakagawa, K; Nezu, K; Ohe, Y; Saijo, N; Sasaki, Y | 1 |
| Avis, I; Cuttitta, F; Gazdar, AF; Kasprzyk, PG; Mulshine, JL; Nakanishi, Y; Steinberg, SM | 1 |
| Hofsli, E; Nissen-Meyer, J | 1 |
| Bauerfeind, R; Reubel, GH | 1 |
| Huismans, DR; Leyva, A; Pieters, R; Veerman, AJ | 2 |
| Monner, DA | 1 |
| Romijn, JC; Schroeder, FH; Verkoelen, CF | 1 |
| Fitch, FW; Kim, DK; Nau, GJ | 1 |
| Hardt, C; Heeg, K; Kabelitz, D; Reimann, J; Wagner, H | 1 |
| Emini, EA; Kostek, BM; Lewis, JA; Robertson, GA; Schleif, WA | 1 |
| Buckley, S; DeLoach, JR; Holt, PS; Norman, JO | 1 |
| Anai, H; Kusumoto, H; Kusumoto, T; Maehara, Y; Sugimachi, K | 1 |
| Campling, BG; Cole, SP; Galbraith, PR; Pym, J | 1 |
| Bejaoui, N; Cinq-Mars, B; Lemieux, P; Pagé, M | 1 |
| Russmann, E | 1 |
| Cannon, M; Leeder, JS; Nakhooda, A; Spielberg, SP | 1 |
| DeLoach, JR; Holt, PS | 1 |
| McHale, AP; McHale, L | 1 |
| Twentyman, P; Wasserman, TH | 1 |
| Cairns, AJ | 1 |
| Koyama, M; Kuroshima, K; Shiho, O; Tada, H; Tsukamoto, K | 1 |
| Ashman, RB | 1 |
| Asari, T; Hisazumi, H; Kobashi, K; Koshida, K; Naito, K; Uchibayashi, T | 1 |
| Jones, JE; Rubin, RL; Uetrecht, JP | 1 |
| Luscombe, M; Twentyman, PR | 1 |
| Buckley, S; Deloach, JR; Holt, PS | 1 |
| Cole, SP | 1 |
| Baguley, BC; Finlay, GJ; Wilson, WR | 1 |
| Gerlier, D; Thomasset, N | 1 |
| Carmichael, J; DeGraff, WG; Gazdar, AF; Minna, JD; Mitchell, JB | 2 |
| Owen, RR | 1 |
| Gibbs, C; Hooton, JW; Paetkau, V | 1 |
| Farías, RN; Leiva, MA; Massa, EM | 1 |
| Peck, R | 1 |
| Chan, G; Poznansky, MJ; Schiff, D | 1 |
| Abdullah, A; Bodin, G; Hiron, H; Pellerin, JL; Rai-el-Balhaa, G | 1 |
| Choury, D; Kaplan, JC | 1 |
| Harriss, JV; Klebe, RJ | 1 |
| Farías, RN; Massa, EM | 2 |
| Mosmann, T | 1 |
| Green, LM; Reade, JL; Ware, CF | 1 |
| Inoue, T; Satoh, M; Tomozawa, Y | 1 |
| Buchbauer, G; Chiba, P; Jäger, W; Päsler, B | 1 |
| Gieni, RS; HayGlass, KT; Li, Y | 1 |
| Boehme, P; Mak, IT; Weglicki, WB | 1 |
| Cooper, MH; Gregory, SH; Starzl, TE; Wing, EJ | 1 |
| Claffey, DC; Ealey, PA; Holly, JM; Lane, PA; Marshall, NJ; Wass, JA; Yateman, ME | 1 |
| Choe, CC; Devenish, RJ; Hatzinisiriou, I; Linnane, AW; Ralph, SJ; Wines, BD | 1 |
| Fukui, Y; Kageyama, H; Ueda, K | 1 |
| Chuang, AJ; Chuang, RY; Killam, KF; Kun, E; Mendeleyev, J | 1 |
| Arakawa, F; Haruno, M; Kuroki, M; Kuwahara, M; Matsuoka, Y; Murakami, M; Nakazato, H; Oikawa, S | 1 |
| Dos Santos, AV; Hussain, RF; Mansouri, M; Nouri, AM; Oliver, RT | 2 |
| Marunouchi, T; Sawada, M; Suzumura, A | 1 |
| Buxser, SE; Decker, DE; Vroegop, SM | 1 |
| Dattani, MT; Ealey, PA; Hassan, MK; Holt, SJ; Marshall, NJ; Sandhu, R; Yateman, ME | 1 |
| Dobbins, AC; Hawtin, SR; Shearman, MS; Tailor, VJ | 1 |
| Hisatsugu, T; Katano, M; Kubota, E; Matsuo, T; Nagumo, F; Tadano, J | 1 |
| Chen, Z; Sato, M; Suzuki, Y; Washio, T | 1 |
| Burek, B; Hrsak, I | 1 |
| Adams, PW; Orosz, CG; VanBuskirk, AM | 1 |
| Christin, L; Diamond, RD; Levitz, SM; Meshulam, T | 1 |
| Chiang, MY; Duh, CY; Hou, RS; Lin, CN | 1 |
| Herrington, J; Iwata, M; Zager, RA | 1 |
| Ishimura, H; Sasaki, F; Takada, N; Uchino, J | 1 |
| Itokawa, Y; Kikuchi, H; Kimura, M; Nakatsu, S; Oda, Y; Zhu, Z | 1 |
| Hall, AG; Matheson, E; Maung, ZT; Proctor, SJ; Reid, MM; Taylor, PR | 1 |
| Andre, JG; Foury, O; Joly-Pharaboz, MO; Mebarki, F; Morel, Y; Nicolas, B; Renaud, M; Soave, MC | 1 |
| Kempermann, G; Volk, B | 1 |
| Eun, HC | 1 |
| Efferth, T; Fabry, U; Glatte, P; Osieka, R | 1 |
| Farzaneh, F; Freeman, GE; Rayner, AP; Trayner, ID | 1 |
| Kawahara, M; Kayada, Y; Munakata, H; Sakamoto, T; Takada, K; Yoshiga, K | 1 |
| Kamenosono, M; Kaneko, I; Sakuraba, Y; Tutumi, S; Yamada, N | 1 |
| Dubertret, L; Marquis, I; Morlière, P; Moysan, A; Richard, A | 1 |
| Hildebrandt, A; Lawen, A; Schwabe, K; Steinheider, G; Traber, R | 1 |
| Egawa, H; Higashiyama, H; Iwata, S; Kagawa, R; Mori, K; Ozawa, K | 1 |
| Gomez-Flores, R; Gupta, S; Mehta, RT; Tamez-Guerra, R | 1 |
| Sawyer, TW | 1 |
| Kato, M; Morishita, T; Nakamura, T; Saitoh, Y | 1 |
| Bourinbaiar, AS; Nagorny, R | 1 |
| Auersperg, N; Elliott, WM | 1 |
| Lelkes, PI; Papadimitriou, E | 1 |
| Elseth, KM; Haines, GK; Maker, VK; Radosevich, JA; Shambaugh, GE | 1 |
| Egawa, M; Hasegawa, T; Hisazumi, H; Sasaki, T; Tanaka, T; Uchibayashi, T | 1 |
| Löwenberg, B; Sonneveld, P; te Boekhorst, PA | 1 |
| Doi, F; Goya, T; Torisu, M; Yoshida, T | 1 |
| Hählen, K; Kaspers, GJ; Pieters, R; Van Wering, ER; Van Zantwijk, I; Veerman, AJ | 1 |
| Kaneshiro, K; Kawashima, M; Kondo, T; Sato, Y; Wada, K; Yamauchi, M | 1 |
| Hawtin, SR; Pollack, SJ; Sadler, II; Shearman, MS; Tailor, VJ | 1 |
| Asawa, S; Konno, K; Shigeta, S; Sudo, K; Watanabe, W; Yokota, T | 1 |
| Alaoui-Jamali, M; Aubin, R; Batist, G; Bramson, J; Christodoulopoulos, G; McQuillan, A; Panasci, LC | 1 |
| Gareis, M; Hanelt, M; Kollarczik, B | 1 |
| Bhakdi, S; Jahn, B; Martin, E; Stueben, A | 1 |
| Bunnak, J; Ito, H; Shinozawa, T; Takigami, M | 1 |
| Hawtin, SR; Pollack, SJ; Sadler, II; Shearman, MS; Tailor, V | 1 |
| Bock, I; Bruchelt, G; Girgert, R; Narr, R; Schweizer, P | 1 |
| Berridge, MV; Horsfield, JA; Tan, AS | 1 |
| Hawtin, SR; Shearman, MS; Tailor, VJ | 1 |
| Balázs, R; Boer, GJ; Hack, N; Resink, A | 1 |
| Coyle, T; Levante, S; Shetler, M; Winfield, J | 1 |
| Izumi, I; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Endo, Y; Fujiwara, T; Hinuma, Y; Hirano, M; Ohno, M; Sato, A; Shudo, K | 1 |
| Konno, K; Shigeta, S; Sudo, K; Yokota, T | 2 |
| Khair-el-Din, TA; Lu, CY; Sicher, SC; Vazquez, MA; Wright, WJ | 1 |
| Katano, M; Matsunaga, H; Mori, M; Nagumo, F; Saita, T | 1 |
| Askew, JN; Sandle, GI; Watson, AJ | 1 |
| Coiffard, L; De Roeck-Holtzhauer, Y; Rivalland, P; Vié, K | 1 |
| Geary, N; Langhans, W; Werling, D | 1 |
| Fox, BW; Hadfield, JA; McGown, AT; Pavlidis, VH; Perry, PJ; Whitworth, C | 1 |
| Clifford, TL; Steele, RJ; Watson, SA | 1 |
| Fujita, H; Hotta, T; Ikenaga, M; Ishizaki, K; Isowa, G; Kiya, K; Kurisu, K; Mikami, T; Saito, Y; Uozumi, T | 1 |
| Aktories, K; Jonas, JC; Just, I; Li, G; Rungger-Brändle, E; Wollheim, CB | 1 |
| Hefti, F; Widmer, HR | 2 |
| Artico, M; Corelli, F; Corrias, S; De Montis, A; La Colla, P; Loi, AG; Mai, A; Marongiu, ME; Massa, S; Ragno, R | 1 |
| Clemens, MG; Schwarz, KB; Seligman, P; Sharma, S; Zieber, TM | 1 |
| Camby, I; Darro, F; Kiss, R; Kruczynski, A; Martinez, J; Pasteels, JL | 1 |
| Garcia-Lloret, M; Guilbert, LJ; Wegmann, TG; Yui, J | 1 |
| Acosta, D; Rodriguez, RJ | 2 |
| Chengappa, MM; Nagaraja, TG; Staats, JJ; Tan, ZL | 1 |
| Balog, JM; Bayyari, GR; Huff, WE; Rath, NC | 1 |
| Doi, E; Kitabatake, N; Trivedi, AB | 1 |
| Bodó, I; Cleveland, WL; Vloka, JD | 1 |
| Koren, G; Neuman, MG; Tiribelli, C | 1 |
| Barrand, MA; Rhodes, T; Twentyman, PR | 1 |
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| Han, F; Lee, IS; Xiao, Y | 1 |
| Akbar, S; Arshad, N; Ijaz, B; Ishtiaq, S; Manzoor, A; Rehman, S; Rehman, U; Tariq, S | 1 |
| Baker, LA; Cornetta, KG; Ghatak, S; Gopalakrishnan, V; Huang, K; Jagdale, G; Khanna, S; Khona, DK; Roy, S; Sen, A; Sen, CK; Singh, K | 1 |
| Isidori, M; Lavorgna, M; Nugnes, R; Orlo, E; Russo, C | 1 |
| Drewa, T; Fekner, Z; Jundziłł, A; Kazimierski, Ł; Kloskowski, T; Krzeszowiak, K; Pokrywczyńska, M; Szeliski, K | 1 |
| Aloufi, N; Baglole, CJ; Eidelman, DH; Shi, F; Traboulsi, H; Trempe, JF | 1 |
| Couri, MRC; de Moraes, J; Enes, KB; Espírito-Santo, MCC; Mengarda, AC; Miguel, FB; Morais, CS; Rodrigues, VC; Siyadatpanah, A; Wilairatana, P | 1 |
18 review(s) available for thiazolyl blue and thiazoles
| Article | Year |
|---|---|
In vitro chemosensitivity testing and its clinical application in human gliomas.
Topics: Amino Acids; Antineoplastic Agents; Biological Factors; Brain Neoplasms; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Gentian Violet; Glioma; Growth Inhibitors; Humans; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Stem Cell Assay | 1989 |
Practical applications of neuronal tissue culture in in vitro toxicology.
Topics: Animals; Cells, Cultured; Chick Embryo; Cholinesterase Inhibitors; Coloring Agents; Insecticides; Neurons; Neutral Red; Organophosphorus Compounds; Prosencephalon; Soil Pollutants; Tetrazolium Salts; Thiazoles | 1995 |
[Application for therapeutic use of deuterium oxide (D2O) against human pancreatic cancer].
Topics: Animals; Cell Division; Cell Movement; Deuterium Oxide; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Neoplasms; Phagocytosis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Multicenter study of MTT and resazurin assays for testing susceptibility to first-line anti-tuberculosis drugs.
Topics: Antitubercular Agents; Coloring Agents; Drug Resistance, Bacterial; Humans; Indicators and Reagents; Latin America; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Reference Values; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tuberculosis, Pulmonary; Xanthenes | 2005 |
Zinc and the diabetic heart.
Topics: Animals; Antioxidants; Biological Transport; Cardiomyopathies; Cell Line; Coloring Agents; Diabetes Complications; Diabetes Mellitus, Experimental; Dietary Supplements; Glutathione; Glutathione Peroxidase; Humans; Metallothionein; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors; Triglycerides; Zinc | 2005 |
Contrast medium-induced nephropathy: the pathophysiology.
Topics: Coloring Agents; Contrast Media; Humans; Kidney Diseases; Kidney Tubules, Distal; Mitochondria; Osmolar Concentration; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity.
Topics: Animals; Apoptosis; Cell Line; Gene Transfer Techniques; Humans; Polyamines; Polyelectrolytes; Polyethyleneimine; Polylysine; Tetrazolium Salts; Thiazoles | 2006 |
The retinoid induced pancreatic cancer redifferentiation-apoptosis sequence and the mitochondria: a suggested obligatory sequence of events.
Topics: Animals; Apoptosis; Cell Cycle; Cell Differentiation; Cell Proliferation; Humans; Membrane Potentials; Mitochondria; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Tretinoin | 2007 |
Vascular endothelium as a target for endogenous ouabain: studies on the effect of ouabain on human endothelial cells.
Topics: Apoptosis; Cardiac Glycosides; Cells, Cultured; Endocytosis; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Ouabain; Phosphatidylinositol 3-Kinases; Signal Transduction; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Tetrazolium Salts; Thiazoles | 2006 |
Vitamin K and rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Fibroblasts; Humans; Models, Biological; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Vitamin K | 2008 |
In vitro assays for the evaluation of drug resistance in tumor cells.
Topics: Cell Survival; Drug Resistance, Neoplasm; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2009 |
Predicting tumour response to anti-HER1 therapy using medical imaging: a literature review and in vitro study of [18F]-FDG incorporation by breast cancer cells responding to cetuximab.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cetuximab; Colony-Forming Units Assay; ErbB Receptors; Female; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles | 2011 |
An overview of colorimetric assay methods used to assess survival or proliferation of mammalian cells.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Colorimetry; Gentian Violet; Humans; Oxazines; Tetrazolium Salts; Thiazoles; Xanthenes | 2011 |
Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Calcium Channel Blockers; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dinoprostone; Humans; Hydrazines; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nimodipine; Oxazepines; Peptide Fragments; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles | 2013 |
Phenotype microarray technology and its application in industrial biotechnology.
Topics: Bacteria; Bacterial Physiological Phenomena; Biotechnology; Color; Microarray Analysis; Optical Imaging; Phenotype; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2014 |
Current methodology of MTT assay in bacteria - A review.
Topics: Bacteria; Biological Assay; Cell Division; Formazans; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2018 |
Copper Coordination Compounds as Biologically Active Agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Infective Agents; Antineoplastic Agents; Biological Factors; Cell Line, Tumor; Copper; Drug Design; Drug Evaluation, Preclinical; Flow Cytometry; HEK293 Cells; Humans; Inhibitory Concentration 50; Ions; Isotopes; Ligands; MCF-7 Cells; Mycobacterium tuberculosis; Oxidation-Reduction; Positron-Emission Tomography; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tuberculosis | 2020 |
Biological evaluation of preceramic organosilicon polymers for various healthcare and biomedical engineering applications: A review.
Topics: Animals; Biocompatible Materials; Bioengineering; Biomedical Engineering; Bone and Bones; Bone Regeneration; Cell Survival; Ceramics; Fibroblasts; Humans; In Vitro Techniques; Materials Testing; Microscopy, Confocal; Organic Chemicals; Polymers; Pressure; Rats; Silicon; Silicones; Tetrazolium Salts; Thiazoles; Tissue Engineering; Wound Healing | 2021 |
17 trial(s) available for thiazolyl blue and thiazoles
| Article | Year |
|---|---|
[MTT assay using fresh surgical specimens with reference to the transfer system and reproducibility in "test center" method].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Coloring Agents; Drug Screening Assays, Antitumor; Female; Hospital Shared Services; Humans; Japan; Laboratories, Hospital; Male; Middle Aged; Neoplasms; Reproducibility of Results; Specimen Handling; Tetrazolium Salts; Thiazoles | 1990 |
A colorimetric assay to evaluate the chemotherapeutic response of children with acute lymphoblastic leukemia (ALL) employing achatininH: a 9-O-acetyl sialic acid binding lectin.
Topics: Acetylation; Child; Child, Preschool; Colorimetry; Coloring Agents; Evaluation Studies as Topic; Female; Humans; Lectins; Lymphoproliferative Disorders; Male; N-Acetylneuraminic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Treatment Outcome | 1999 |
The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bilirubin; Chromatography, High Pressure Liquid; Coloring Agents; Cyclosporins; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Inhibitory Concentration 50; K562 Cells; Microsomes, Liver; Models, Chemical; Paclitaxel; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors | 2001 |
Locoregional chemotherapy for patients with pancreatic cancer intra-arterial adjuvant chemotherapy after pancreatectomy with portal vein resection.
Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Coloring Agents; Drug Screening Assays, Antitumor; Female; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Pancreatectomy; Pancreatic Neoplasms; Pilot Projects; Portal Vein; Prognosis; Survival Rate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects.
Topics: Adult; Blotting, Western; Cell Differentiation; Cells, Cultured; Cytokines; Female; Histamine; Histamine Release; Humans; Hypersensitivity, Immediate; Insecticides; Interferon-gamma; Interleukin-4; Male; No-Observed-Adverse-Effect Level; Pyrethrins; RNA; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetrazolium Salts; Thiazoles | 2003 |
The aging human myocardium: tolerance to ischemia and responsiveness to ischemic preconditioning.
Topics: Adult; Aged; Aged, 80 and over; Aging; Biomarkers; Creatine Kinase; Female; Heart; Humans; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Myocardial Ischemia; Tetrazolium Salts; Thiazoles; United Kingdom | 2003 |
Cytotoxicity testing of endodontic sealers: a new method.
Topics: Analysis of Variance; Animals; Biocompatible Materials; Calcium Hydroxide; Cell Line; Coloring Agents; Epoxy Resins; Fibroblasts; Gutta-Percha; Humans; Mice; Root Canal Filling Materials; Root Canal Obturation; Root Canal Preparation; Salicylates; Tetrazolium Salts; Thiazoles; Zinc Oxide-Eugenol Cement | 2003 |
In vitro-in vivo model for evaluating the antiviral activity of amprenavir in combination with ritonavir administered at 600 and 100 milligrams, respectively, every 12 hours.
Topics: Adult; Anti-HIV Agents; Antiviral Agents; Carbamates; Cell Line; Cells, Cultured; Drug Combinations; Female; Furans; HIV Antigens; Humans; Male; Middle Aged; Models, Biological; Protein Binding; Ritonavir; Sulfonamides; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Bioembolisation for unresectable hepatocellular carcinoma: preliminary results of a translational research study.
Topics: Adult; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemoembolization, Therapeutic; Coloring Agents; Embolization, Therapeutic; Female; Hepatic Artery; Humans; Hypoxia; Inhibitory Concentration 50; Interferon alpha-2; Interferon-alpha; Interferons; Iodized Oil; Liver Neoplasms; Male; Middle Aged; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome | 2004 |
In vitro and in vivo evaluation of combined calcitriol and cisplatin in dogs with spontaneously occurring tumors.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Calcitriol; Cell Line, Tumor; Cisplatin; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Injections, Intravenous; Neoplasms; Tetrazolium Salts; Thiazoles; Vitamins | 2008 |
Potential use of chitosan nanoparticles for oral delivery of DNA vaccine in Asian sea bass (Lates calcarifer) to protect from Vibrio (Listonella) anguillarum.
Topics: Administration, Oral; Animals; Bacterial Outer Membrane Proteins; Bass; Cell Line; Chitosan; Escherichia coli; Fish Diseases; Gene Expression Regulation; Gram-Negative Bacterial Infections; Immune Sera; Listonella; Nanoparticles; Plasmids; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Vaccination; Vaccines, DNA | 2008 |
Optimal cytocompatibility of a bioceramic nanoparticulate cement in primary human mesenchymal cells.
Topics: Aluminum Compounds; Biocompatible Materials; Calcium Compounds; Cell Survival; Cells, Cultured; Ceramics; Coloring Agents; Culture Media; Culture Media, Conditioned; Dental Cements; Drug Combinations; Humans; Materials Testing; Mesoderm; Nanoparticles; Oxides; Retrograde Obturation; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Synthesis and characterization of triethylene glycol dimethacrylate nanocapsules used in a self-healing bonding resin.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Chromatography, High Pressure Liquid; Coloring Agents; Composite Resins; Dental Bonding; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Fibroblasts; Humans; Materials Testing; Mice; Microscopy, Electron, Scanning; Nanocapsules; Polyethylene Glycols; Polymethacrylic Acids; Polyurethanes; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles | 2011 |
Effect of desensitising paste containing 8% arginine and calcium carbonate on biofilm formation of Streptococcus mutans in vitro.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Arginine; Bacterial Adhesion; Biofilms; Calcium Carbonate; Coloring Agents; Dental Prophylaxis; Dentifrices; Dentin; Dentin Desensitizing Agents; Fluorides; Humans; Imaging, Three-Dimensional; Lactic Acid; Microbial Viability; Microscopy, Electron, Scanning; Phosphates; Silicates; Streptococcus mutans; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2013 |
An in vitro and in vivo comparison of the effect of Stevia rebaudiana extracts on different caries-related variables: a randomized controlled trial pilot study.
Topics: Adult; Bacterial Load; Bacteriological Techniques; Biofilms; Coloring Agents; Dental Caries; Dental Plaque; Diterpenes, Kaurane; Female; Follow-Up Studies; Glucosides; Humans; Hydrogen-Ion Concentration; Male; Mouthwashes; Pilot Projects; Plant Extracts; Spectrophotometry; Stevia; Streptococcus mutans; Sucrose; Sweetening Agents; Tetrazolium Salts; Thiazoles; Young Adult | 2014 |
Crenolanib is a potent inhibitor of FLT3 with activity against resistance-conferring point mutants.
Topics: Antineoplastic Agents; Benzimidazoles; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Piperidines; Point Mutation; Prognosis; Proto-Oncogene Proteins c-kit; Sequence Analysis, DNA; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Impacts of CLA and dietary concentrate proportion on blood metabolite concentration and proliferation of peripheral blood mononuclear cells of periparturient dairy cows.
Topics: Animal Nutritional Physiological Phenomena; Animals; Bilirubin; Blood Proteins; Cattle; Cell Proliferation; Diet; Dietary Supplements; Female; Insulin-Like Growth Factor I; Leukocytes, Mononuclear; Linoleic Acids, Conjugated; Liver; Models, Statistical; Postpartum Period; Pregnancy; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors; Triglycerides; Trypan Blue | 2015 |
4358 other study(ies) available for thiazolyl blue and thiazoles
| Article | Year |
|---|---|
A new assay for diaphorase activity in reagent formulations, based on the reduction of thiazolyl blue.
Topics: Clostridium; Dihydrolipoamide Dehydrogenase; Formazans; Hydrogen-Ion Concentration; Kinetics; NAD; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1979 |
Evaluation of surfactant cytotoxicity potential by primary cultures of ocular tissues: I. Characterization of rabbit corneal epithelial cells and initial injury and delayed toxicity studies.
Topics: Animal Testing Alternatives; Animals; Cells, Cultured; Coloring Agents; Cornea; Epithelial Cells; Epithelium; Fluorescent Antibody Technique; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Keratins; L-Lactate Dehydrogenase; Male; Neutral Red; Rabbits; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 1992 |
Rapid immunostaining of live nerve for identification of sensory and motor fasciculi.
Topics: Animals; Cells, Cultured; Motor Neurons; Neurons, Afferent; Rabbits; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensory Receptor Cells; Spinal Cord; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1992 |
A rapid colorimetric assay with the tetrazolium salt MTT and phenazine methosulfate (PMS) for viability of Entamoeba histolytica.
Topics: Animals; Cell Survival; Colorimetry; Entamoeba histolytica; Methylphenazonium Methosulfate; Nephelometry and Turbidimetry; Oxidation-Reduction; Reproducibility of Results; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1992 |
Cytoprotective effect of dilazep on hydrogen peroxide-perturbed vascular endothelial cells.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Colorimetry; Dilazep; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelium, Vascular; Hydrogen Peroxide; Hypoxia; Prothrombin; Pulmonary Artery; Tetrazolium Salts; Thiazoles; Thiourea; Time Factors | 1992 |
Inorganic thiophosphate effects on chromaffin cell structure and function.
Topics: Animals; Catecholamines; Cells, Cultured; Chromaffin System; Coloring Agents; Culture Media; Electrophoresis, Polyacrylamide Gel; Microscopy, Electron; Neutral Red; Nicotine; Osmolar Concentration; Phosphates; Tetrazolium Salts; Thiazoles | 1992 |
[Tetrazolium-based colorimetric assay (MTT) and its application in chemosensitivity testing of antitumor Chinese medicine].
Topics: Antineoplastic Agents, Phytogenic; Colorimetry; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Ficusin; Harringtonines; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1992 |
[Cell culture and its application--in vitro evaluation of anticancer activity using human tumor cell lines].
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Test for chemotherapeutic sensitivity of cerebral gliomas: use of colorimetric MTT assay.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Death; Colorimetry; Drug Resistance; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Reproducibility of Results; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Use of a soluble tetrazolium/formazan assay for chicken cells.
Topics: Animals; Cell Division; Cells, Cultured; Chickens; Cytological Techniques; Fibroblasts; Formazans; Herpesvirus 2, Gallid; Indicators and Reagents; Lymphocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Growth modulatory effects of some 6-methylenic steroids on human and hamster pancreatic adenocarcinoma cells in vitro.
Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cricetinae; Drug Screening Assays, Antitumor; Humans; Pancreatic Neoplasms; Steroids; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 1992 |
Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Cell Division; Colorimetry; Disease Models, Animal; Gene Expression; Humans; Immunization; Immunotherapy; Mice; Mice, Nude; Neoplasm Transplantation; Proto-Oncogene Proteins; Receptor, ErbB-2; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1992 |
The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Epirubicin; Humans; Membrane Glycoproteins; Tetrazolium Salts; Thiazoles; Trypan Blue; Verapamil; Vinblastine | 1992 |
Growth and death behaviour of anchorage-independent animal cells immobilized within porous support matrices.
Topics: Animals; Cell Count; Cell Death; Cell Division; Coloring Agents; L-Lactate Dehydrogenase; Mice; Polyvinyls; Resins, Plant; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Toxicity of dimethyl sulfoxide as a solvent in bioassay system with HeLa cells evaluated colorimetrically with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide.
Topics: Animals; Cell Line; Cell Survival; Colorimetry; Coloring Agents; Dimethyl Sulfoxide; HeLa Cells; Humans; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
An easy-to-handle semi-automated method for media development using a colorimetric viability assay and fractional factorial designs.
Topics: Animals; Automation; Cell Count; Cell Survival; Cells, Cultured; CHO Cells; Colorimetry; Cricetinae; Culture Media; Hydrogen-Ion Concentration; Mice; Tetrazolium Salts; Thiazoles | 1992 |
A modified colorimetric MTT assay adapted for primary cultured hepatocytes: application to proliferation and cytotoxicity assays.
Topics: Carbon Tetrachloride; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Dimethylnitrosamine; Galactosamine; Liver; Tetrazolium Salts; Thiazoles; Toxicology | 1992 |
Methods for the estimation of the number and quality of animal cells immobilized in carbohydrate gels.
Topics: Animals; Biotechnology; Cell Count; Cell Division; Cell Survival; Coloring Agents; DNA; Fixatives; Fluorescent Dyes; Gels; Glutaral; Hybridomas; Mice; Rosaniline Dyes; Sepharose; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trypan Blue | 1990 |
The protein kinase C inhibitor, calphostin C, inhibits succinate-dependent mitochondrial reduction of MTT by a mechanism that does not involve protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow; Carbazoles; Cell Division; Cell Line; Coloring Agents; DNA Replication; Indoles; Isoquinolines; Kinetics; Mice; Mice, Inbred C3H; Mitochondria; Naphthalenes; Oxidation-Reduction; Piperazines; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Succinates; Tetrazolium Salts; Thiazoles; Thymidine | 1992 |
MTT assays allow quick and reliable measurement of the response of human tumour cells to photodynamic therapy.
Topics: Adenocarcinoma; Breast Neoplasms; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Hematoporphyrin Derivative; Hematoporphyrins; Humans; Photochemotherapy; Radiation-Sensitizing Agents; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Islet cell metabolism is reflected by the MTT (tetrazolium) colorimetric assay.
Topics: Alloxan; Animals; Cell Line; Cells, Cultured; Colorimetry; Glucose; Indicators and Reagents; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Male; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Streptozocin; Tetrazolium Salts; Thiazoles | 1992 |
Quantitative colorimetric assay for basic fibroblast growth factor using bovine endothelial cells and heparin.
Topics: Animals; Biological Assay; Cattle; Cell Division; Cells, Cultured; Colorimetry; Culture Media; Endothelium; Fibroblast Growth Factor 2; Heparin; Myocardium; Tetrazolium Salts; Thiazoles | 1992 |
A new 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay for testing macrophage cytotoxicity to L1210 and its drug-resistant cell lines in vitro.
Topics: Animals; Coloring Agents; Cytotoxicity Tests, Immunologic; Drug Resistance; Leukemia L1210; Macrophages; Male; Mice; Mice, Inbred DBA; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
Resistance circumvention strategies tested in clinical leukaemia specimens using the MTT colorimetric assay.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1992 |
Validation of the MTT dye assay for enumeration of cells in proliferative and antiproliferative assays.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Survival; Colorimetry; Coloring Agents; Ethidium; Formazans; Humans; Interferon Type I; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondria; Recombinant Proteins; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Chemosensitivity testing of fresh human gastric cancer with highly purified tumour cells using the MTT assay.
Topics: Adult; Aged; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Oxidized HDL are much less cytotoxic to lymphoblastoid cells than oxidized LDL.
Topics: Arteriosclerosis; Cell Line; Copper; Copper Sulfate; Fatty Acids, Unsaturated; Humans; L-Lactate Dehydrogenase; Lipoproteins, HDL; Lipoproteins, LDL; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Trypan Blue; Ultraviolet Rays | 1992 |
Radiosensitivity testing of human malignant gliomas.
Topics: Brain Neoplasms; Colony-Forming Units Assay; Colorimetry; Coloring Agents; Glioma; Humans; Radiation Tolerance; Survival Analysis; Tetrazolium Salts; Thiazoles | 1992 |
Mitochondrial glutathione and methyl iodide-induced neurotoxicity in primary neural cell cultures.
Topics: Animals; Cell Membrane; Cell Survival; Cells, Cultured; Cerebral Cortex; Coloring Agents; Cytosol; Digitonin; Glutathione; Hydrocarbons, Iodinated; Intracellular Membranes; Mice; Mitochondria; Tetrazolium Salts; Thiazoles | 1992 |
Noncolorimetric measurement of cell activity in three-dimensional histoculture using the tetrazolium dye 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide: the pixel image analysis of formazan crystals.
Topics: Antineoplastic Agents; Coloring Agents; Crystallization; Drug Screening Assays, Antitumor; Formazans; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
A quantitative microassay of carbohydrate-mediated cell adhesion to glycoconjugates immobilized on polystyrene plates.
Topics: Animals; Carbohydrate Sequence; Cell Adhesion; Cell Line; Colorimetry; Coloring Agents; Disaccharides; Glycoconjugates; Glycosides; Kinetics; Liver; Molecular Sequence Data; Monosaccharides; Polystyrenes; Tetrazolium Salts; Thiazoles | 1992 |
Quantifying proliferation of cultured human and rabbit airway smooth muscle cells in response to serum and platelet-derived growth factor.
Topics: Animals; Blood; Bronchi; Cell Division; Cells, Cultured; Colorimetry; Coloring Agents; Humans; Muscle, Smooth; Platelet-Derived Growth Factor; Rabbits; Rosaniline Dyes; Tetrazolium Salts; Thiazoles; Trachea | 1992 |
Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells.
Topics: Animals; Benzamides; Cell Death; Coloring Agents; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; NAD; NADP; Nerve Growth Factors; Oxidation-Reduction; PC12 Cells; Poly Adenosine Diphosphate Ribose; Rats; Tetrazolium Salts; Thiazoles | 1992 |
The mechanism of Hg2+ toxicity in cultured human oral fibroblasts: the involvement of cellular thiols.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cysteine; Dental Amalgam; Deoxyglucose; Fibroblasts; Glutathione; Humans; Mercury; Methionine Sulfoximine; Mouth; Neutral Red; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 1992 |
[Sensitivity test for anti-tumor agents-3. MTT assay and its clinical effect].
Topics: Antineoplastic Agents; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Methotrexate; Mitomycin; Ovarian Neoplasms; Predictive Value of Tests; Tetrazolium Salts; Thiazoles; Uterine Neoplasms | 1992 |
Differential macrophage-mediated cytotoxicity to P388 leukemia cells and its drug-resistant cells examined by a new MTT assay.
Topics: Animals; Coloring Agents; Drug Resistance; Drug Screening Assays, Antitumor; Leukemia P388; Macrophage Activation; Macrophages; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
A tetrazolium-based colorimetric assay for quantification of HIV-1-induced cytopathogenicity in monocyte-macrophages exposed to macrophage-colony-stimulating factor.
Topics: Colorimetry; Coloring Agents; Cytopathogenic Effect, Viral; Evaluation Studies as Topic; HIV-1; Humans; In Vitro Techniques; Macrophage Colony-Stimulating Factor; Macrophages; Microbial Sensitivity Tests; Monocytes; Tetrazolium Salts; Thiazoles; Virology; Zidovudine | 1992 |
Effects of high glucose concentration on survival and respiration of human endothelial cells.
Topics: Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Culture Media; Electron Transport; Endothelium, Vascular; Glucose; Humans; Tetrazolium Salts; Thiazoles; Trypan Blue | 1992 |
Application of the chemiluminescent assay to cytotoxicity test: detection of menadione-catalyzed H2O2 production by viable cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Count; Cell Line; Cell Survival; Coloring Agents; Humans; Hydrogen Peroxide; Indicators and Reagents; Luminescent Measurements; Male; Mice; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tomatine; Tumor Cells, Cultured; Vitamin K | 1992 |
Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1).
Topics: Animals; Calcium; Carbohydrate Dehydrogenases; Cell Line; Diazoxide; Enzyme Induction; Glycerolphosphate Dehydrogenase; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mitochondria; Rats; Streptozocin; Tetrazolium Salts; Thiazoles | 1992 |
Augmentation of monocyte-mediated cytocidal activity by a low dose tumour necrosis factor measured by the kinetic colorimetric microplate assay.
Topics: Colorimetry; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Humans; Kinetics; Mathematics; Melanoma, Experimental; Monocytes; Regression Analysis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Macrophage response to microtextured silicone.
Topics: Animals; Cell Adhesion; Cell Division; Female; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Silicones; Surface Properties; Tetrazolium Salts; Thiazoles | 1992 |
Tetrazolium [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] reduction by mycoplasmas.
Topics: Acholeplasma; Cell Division; Mycoplasma; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1992 |
Assessment of antineoplastic agents by MTT assay: partial underestimation of antiproliferative properties.
Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Nitrosourea Compounds; Phosphorylcholine; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vinblastine | 1992 |
Thymidylate synthase as a target enzyme for the melanoma-specific toxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol.
Topics: Antineoplastic Agents; Cell Division; Cell-Free System; Cysteamine; DNA; Humans; Kinetics; Leucovorin; Melanoma; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Tetrazolium Salts; Theophylline; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
In vitro screening of crude extracts and pure metabolites obtained from marine invertebrates for the treatment of breast cancer.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Depsipeptides; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Invertebrates; Marine Biology; Peptides, Cyclic; Tetrazolium Salts; Thiazoles; Tissue Extracts; Tumor Cells, Cultured | 1992 |
The effects of 5-fluorouracil and mitomycin C on the corneal endothelium.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorouracil; Mitomycin; Tetrazolium Salts; Thiazoles; Time Factors | 1992 |
Lack of enantio-selectivity in the in vitro antitumour cytotoxicity and membrane-damaging activity of ether lipid SRI 62-834: further evidence for a non-receptor-mediated mechanism of action.
Topics: Antineoplastic Agents; Azepines; Cell Death; Cell Membrane; Furans; Humans; Phospholipid Ethers; Platelet Aggregation Inhibitors; Stereoisomerism; Tetrazolium Salts; Thiazoles; Triazoles; Tumor Cells, Cultured | 1992 |
A new MTT assay for examining the cytotoxicity of activated macrophages towards the non-adherent P388 leukaemia cell line.
Topics: Animals; Colorimetry; Cytotoxicity, Immunologic; Leukemia P388; Macrophage Activation; Macrophages; Mice; Tetrazolium Salts; Thiazoles | 1992 |
Novel quantitative methods for the determination of biomaterial cytotoxicity.
Topics: Animals; Biocompatible Materials; Cell Line; Cells, Cultured; Colorimetry; Coloring Agents; Cricetinae; Fluorometry; Indicators and Reagents; Materials Testing; Polyethylenes; Polyvinyl Chloride; Tetrazolium Salts; Thiazoles | 1992 |
Potentiation of heroin and methadone hepatotoxicity by ethanol: an in vitro study using cultured human hepatocytes.
Topics: Biopsy; Cells, Cultured; Drug Interactions; Ethanol; Female; Glutathione; Glycogen; Heroin; Humans; L-Lactate Dehydrogenase; Liver; Male; Methadone; Oxidation-Reduction; Prospective Studies; Tetrazolium Salts; Thiazoles; Urea | 1992 |
Assessment of cytotoxicity assays as predictors of ocular irritation of pharmaceuticals.
Topics: Animals; Cells, Cultured; Cornea; Drug-Related Side Effects and Adverse Reactions; Epithelium; Leucine; Neutral Red; Rabbits; Tetrazolium Salts; Thiazoles; Toxicology | 1992 |
Antineoplastic activity of mitoxantrone and its biological interactions in parental and multidrug resistant subline of P388 murine leukemia cells.
Topics: Alkylating Agents; Animals; Biotransformation; DNA Damage; DNA, Neoplasm; Drug Resistance; Drug Screening Assays, Antitumor; Free Radical Scavengers; Glutathione; Leukemia P388; Macromolecular Substances; Mice; Mitoxantrone; Neoplasm Proteins; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Indium inhibits gap junctional communication between rat hepatocytes in primary culture.
Topics: Animals; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Indium; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred Strains; Tetrazolium Salts; Thiazoles | 1992 |
[Estimating doses of anti-cancer agents in sensitivity tests in vitro].
Topics: Adenocarcinoma; Antineoplastic Agents; Carboplatin; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Mitomycin; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 1992 |
Macrophages stimulated by receptor-ligand interactions exhibit differences in cell-cycle kinetics during tumor growth: stimulation at Mac-1 and Mac-3 receptors alters DNA synthesis.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation; Cell Cycle; DNA, Neoplasm; Fibrosarcoma; Flow Cytometry; Fluorescent Antibody Technique; Ligands; Macrophage Activation; Macrophage-1 Antigen; Male; Mice; Mice, Inbred BALB C; Receptors, Immunologic; Tetrazolium Salts; Thiazoles | 1992 |
Adherence to and cytotoxicity of Escherichia coli for eucaryotic cell lines quantified by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide).
Topics: Bacterial Adhesion; Cell Line; Coloring Agents; Epithelium; Escherichia coli; Eukaryotic Cells; Hemolysin Proteins; Humans; Kidney Tubules; Tetrazolium Salts; Thiazoles; Urinary Tract Infections; Virulence | 1992 |
Role of interferon gamma and tumour necrosis factor alpha in monocyte-mediated cytostasis and cytotoxicity against a human histiocytic lymphoma cell line.
Topics: Cell Death; Colorimetry; Cytotoxicity, Immunologic; Humans; Immunotherapy, Adoptive; Interferon-gamma; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Antiproliferative activity of vinorelbine (Navelbine) against six human melanoma cell lines.
Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Colony-Forming Units Assay; Humans; Melanoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vinblastine; Vincristine; Vindesine; Vinorelbine | 1992 |
Activity of two platinum-linked phosphonic acids against autochthonous rat colorectal cancer as well as in two human colon-cancer cell lines.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Male; Organophosphonates; Organophosphorus Compounds; Organoplatinum Compounds; Rats; Rats, Inbred Lew; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
[Strategy for therapy of malignant ascites using MTT assay].
Topics: Antineoplastic Agents; Ascitic Fluid; Breast Neoplasms; Cisplatin; Clinical Protocols; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part I: Evaluation of test-specific variables.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Division; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Kinetics; Mitochondria; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
The MTT assay for chemosensitivity testing of human tumors of the central nervous system. Part II: Evaluation of patient- and drug-specific variables.
Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Glioma; Humans; Mitomycin; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
NADH-dependent dehydrogenase activity estimation by flow cytometric analysis of 3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.
Topics: Animals; Chloramphenicol; Flow Cytometry; Glycolysis; Leukemia L1210; Mice; Mitochondria; NADH Dehydrogenase; Oxidation-Reduction; Temperature; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Implication of glucocorticoid receptors in the stimulation of human glioma cell proliferation by dexamethasone.
Topics: Cell Division; Dexamethasone; Glioma; Humans; Mifepristone; Receptors, Glucocorticoid; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Reduced drug accumulation in a newly established human lung squamous-carcinoma cell line resistant to cis-diamminedichloroplatinum(II).
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; Cisplatin; Drug Resistance; Humans; Lung Neoplasms; Platinum; Tetrazolium Salts; Thiazoles | 1992 |
Antioxidant effect of retinoic acid on PC12 rat pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Animals; Antioxidants; Cell Survival; Hydrogen Peroxide; Iodine Radioisotopes; Methionine; Nerve Growth Factors; Oxidation-Reduction; Pheochromocytoma; Rats; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured | 1991 |
An application of tetrazolium (MTT) colorimetric assay for the screening of anti-herpes simplex virus compounds.
Topics: Animals; Antiviral Agents; Cell Adhesion; Cell Line; Colorimetry; Coloring Agents; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Humans; Simplexvirus; Tetrazolium Salts; Thiazoles; Virology; Virus Replication | 1991 |
Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia.
Topics: Antineoplastic Agents; Asparaginase; Chi-Square Distribution; Child; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Remission Induction; Tetrazolium Salts; Thiazoles; Thioguanine; Tumor Cells, Cultured; Vincristine | 1991 |
Brugia malayi and Acanthocheilonema viteae: antifilarial activity of transglutaminase inhibitors in vitro.
Topics: Animals; Brugia; Cadaverine; Cystamine; Dipetalonema; Female; Filaricides; Iodoacetamide; Male; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Transglutaminases | 1991 |
Expression of the multidrug transporter P-glycoprotein and in vitro chemosensitivity: correlation with in vivo response to chemotherapy in acute myeloid leukemia.
Topics: Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Child; Colorimetry; Drug Resistance; Female; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Male; Membrane Glycoproteins; Middle Aged; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
A sensitive antiviral neutralization bioassay for measuring antibodies to interferons.
Topics: Animals; Antibodies; Biological Assay; Cytopathogenic Effect, Viral; Enzyme-Linked Immunosorbent Assay; Humans; Interferons; Rabbits; Tetrazolium Salts; Thiazoles | 1990 |
Chemosensitivity testing of primary human renal cell carcinoma by a tetrazolium based microculture assay (MTT).
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Drug Screening Assays, Antitumor; Evaluation Studies as Topic; Humans; Kidney Neoplasms; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
A simple assay for quantifying the inducible adherence of neutrophils.
Topics: Biological Assay; Blood Physiological Phenomena; Cell Adhesion; Colony-Stimulating Factors; Coloring Agents; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Interferon-gamma; Leukocyte Count; Neutrophils; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1990 |
Evaluation of antiproliferative agents using a cell-culture model.
Topics: Animals; Bleomycin; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Cricetinae; Cytarabine; Drug Evaluation, Preclinical; Floxuridine; Fluorouracil; Tetrazolium Salts; Thiazoles; Time Factors; Uridine | 1990 |
Visualization of alkaline phosphatase-labelled antibodies on immunoblots by means of formazan staining using indoxyl phosphate and thiazolyl blue.
Topics: Alkaline Phosphatase; Antibodies; Collodion; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Formazans; Immunoblotting; Indoles; Polyvinyl Chloride; Sensitivity and Specificity; Serum Albumin; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1990 |
Tumor necrosis factor-alpha inhibits human chorionic gonadotropin secretion.
Topics: beta 2-Microglobulin; Blotting, Northern; Cell Division; Chorionic Gonadotropin; Female; Humans; Pregnancy; Pregnancy Trimester, First; Radioimmunoassay; RNA, Messenger; Tetrazolium Salts; Thiazoles; Trophoblasts; Trypan Blue; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
[Comparison between clinical response and in vitro chemosensitivity of solid tumors in the succinic dehydrogenase inhibition test].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Stomach Neoplasms; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Further examination of the selective toxicity of CCl4 in rat liver slices.
Topics: Animals; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Fasting; Kinetics; Lipid Peroxidation; Liver; Male; Rats; Rats, Inbred Strains; Tetrazolium Salts; Thiazoles; Time Factors | 1992 |
In vitro succinate dehydrogenase chemosensitivity of gastric carcinoma--relationship to DNA content.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Nucleus; DNA; Female; Humans; In Vitro Techniques; Male; Middle Aged; Stomach Neoplasms; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1992 |
Expression of MDR1 and glutathione S transferase-pi genes and chemosensitivities in human gastrointestinal cancer.
Topics: Adenocarcinoma; Blotting, Northern; Cell Line; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Resistance; Glutathione Transferase; Humans; Nucleic Acid Hybridization; RNA, Messenger; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 1992 |
Preparation and kinetic properties of 5-ethylphenazine-lactate-dehydrogenase-NAD+ conjugate, a semisynthetic lactate oxidase showing a hide-and-seek effect.
Topics: Animals; Chromatography, Gel; Kinetics; L-Lactate Dehydrogenase; Mathematics; Mixed Function Oxygenases; Muscles; NAD; Oxygen; Phenazines; Rabbits; Tetrazolium Salts; Thiazoles | 1992 |
[Standard deviation of inhibition index of chemosensitivity testing using the MTT assay].
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Mathematics; Mice; Tetrazolium Salts; Thiazoles | 1992 |
Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix.
Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Collagen; Colonic Neoplasms; Culture Media; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1992 |
Disruption of cellular energy balance by suramin in intact human prostatic carcinoma cells, a likely antiproliferative mechanism.
Topics: Biological Transport; Calcium; Carcinoma; Cell Division; Energy Metabolism; Epidermal Growth Factor; Humans; In Vitro Techniques; Male; Microscopy, Electron; Mitochondria; Oxidoreductases; Prostatic Neoplasms; Rhodamine 123; Rhodamines; Suramin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
In vitro chemosensitivity of lymphoblasts at relapse in childhood leukemia using the MTT assay.
Topics: Acute Disease; Antineoplastic Agents; Child; Colorimetry; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Rapid colorimetric assay for the quantification of leukemia inhibitory factor (LIF) and interleukin-6 (IL-6).
Topics: Animals; Colorimetry; Growth Inhibitors; Humans; In Vitro Techniques; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Experimental; Leukemia, Myeloid; Lymphokines; Mice; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
An improved colorimetric assay for tumor necrosis factor using WEHI 164 cells cultured on novel microtiter plates.
Topics: Animals; Biological Assay; Cell Line; Cells, Cultured; Colorimetry; Fibrosarcoma; In Vitro Techniques; Macrophages; Mice; Neutral Red; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1991 |
[Measurement of cellular activity with the MTT test. Optimization of the method].
Topics: Cell Line; Cells; Humans; In Vitro Techniques; Methods; Mitochondria; Oxidation-Reduction; Oxidoreductases; Spectrum Analysis; Tetrazolium Salts; Thiazoles | 1991 |
The MTT-assay as a rapid test for cell proliferation and cell killing: application to human peripheral blood lymphocytes (PBL).
Topics: Cell Death; Cell Division; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Methods; Mitochondria; Oxidation-Reduction; Oxidoreductases; Tetrazolium Salts; Thiazoles; Time Factors | 1991 |
Cytotoxicity test using blastocyst-derived euploid embryonal stem cells: a new approach to in vitro teratogenesis screening.
Topics: Animals; Blastocyst; Cell Survival; Coloring Agents; Indicators and Reagents; Mice; Mice, Inbred Strains; Neutral Red; Organic Chemicals; Stem Cells; Teratogens; Tetrazolium Salts; Thiazoles | 1991 |
Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing.
Topics: Calorimetry; Carcinoma, Squamous Cell; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Chemosensitivity testing with highly purified fresh human tumour cells with the MTT colorimetric assay.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Separation; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Female; Humans; Male; Middle Aged; Neoplasms; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Dithranol-induced cytotoxicity in primary cultures of rat epidermal keratinocytes. I. The role of reactive oxygen species.
Topics: Animals; Anthralin; Cells, Cultured; Cytotoxins; Dose-Response Relationship, Drug; Keratinocytes; L-Lactate Dehydrogenase; Mitochondria; Neutral Red; Oxygen Consumption; Rats; Rats, Inbred Strains; Superoxides; Tetrazolium Salts; Thiazoles | 1991 |
Different inhibitory actions of cyclosporine A and cyclosporine A-acetate on lipopolysaccharide-, interleukin 1-, 1,25 dihydroxyvitamin D3- and parathyroid hormone-stimulated calcium and lysosomal enzyme release from mouse calvaria in vitro.
Topics: Acetylglucosaminidase; Animals; Bone and Bones; Calcitriol; Calcium; Coloring Agents; Cyclosporins; Interleukin-1; Lipopolysaccharides; Lysosomes; Mice; Organ Culture Techniques; Oxidation-Reduction; Parathyroid Hormone; Recombinant Proteins; Salmonella; Tetrazolium Salts; Thiazoles | 1991 |
Cell mediated cytotoxicity against U 937 cells by human monocytes and macrophages in a modified colorimetric MTT assay. A methodological study.
Topics: Cell Count; Cells, Cultured; Colorimetry; Coloring Agents; Cytotoxicity Tests, Immunologic; Humans; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture.
Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Coloring Agents; Drug Evaluation; Drug Screening Assays, Antitumor; Formazans; Humans; Methylphenazonium Methosulfate; Mice; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Differential properties of cisplatin and tetraplatin with respect to cytotoxicity and perturbation of cellular glutathione levels.
Topics: Animals; Antineoplastic Agents; Cell Line; Cisplatin; Coloring Agents; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Mammary Neoplasms, Experimental; Mice; Organoplatinum Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Differential effects of oltipraz and its oxy-analogue on the viability of Schistosoma mansoni and the activity of glutathione S-transferase.
Topics: Animals; Dinitrochlorobenzene; Female; Glutathione; Glutathione Transferase; Kinetics; Male; Mice; Pyrazines; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Tetrazolium Salts; Thiazoles; Thiones; Thiophenes | 1991 |
A colorimetric assay for quantitating bovine neutrophil bactericidal activity.
Topics: Analysis of Variance; Animals; Cattle; Cattle Diseases; Colchicine; Colony Count, Microbial; Colorimetry; Cytochalasin B; Interferon-gamma; Neutrophils; Recombinant Proteins; Serum Bactericidal Test; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1991 |
The influence of stromal cells on the MTT assay (I)--In vitro chemosensitivity of the tumor and stromal cells to mitomycin C.
Topics: Drug Screening Assays, Antitumor; Humans; Mitomycin; Mitomycins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 1991 |
The influence of stromal cells on the MTT assay (II)--Study on the nude mouse system.
Topics: Animals; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Mitomycin; Mitomycins; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 1991 |
[Sensitivity test of anti-tumor agents. 2. Application of MTT assay].
Topics: Antineoplastic Agents; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Melphalan; Mitomycin; Mitomycins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
[Chemosensitivity test for gastric cancer by in vitro MTT assay].
Topics: Antineoplastic Agents; Carbazilquinone; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Mitomycin; Mitomycins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Preparation and kinetic properties of 5-ethylphenazine-glucose-dehydrogenase-NAD+ conjugate, a semisynthetic glucose oxidase.
Topics: Binding Sites; Catalysis; Glucose 1-Dehydrogenase; Glucose Dehydrogenases; Glucose Oxidase; Kinetics; NAD; Oxidation-Reduction; Oxygen; Phenazines; Polyethylene Glycols; Tetrazolium Salts; Thiazoles | 1991 |
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazolium salt XTT.
Topics: Animals; Cell Division; Cell Survival; Colorimetry; Coloring Agents; Concanavalin A; Dose-Response Relationship, Drug; In Vitro Techniques; Interleukin-2; Interleukin-4; Leukemia, Myeloid; Mast Cells; Methylphenazonium Methosulfate; Mice; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Vitamin K | 1991 |
[Establishment of transplantable human colon cancer cell lines, chemosensitivity of colon carcinomas and the serially transplantable strains with MTT assay].
Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
An improved method for visualizing baculovirus plaques in cell agarose overlays.
Topics: Animals; Baculoviridae; Coloring Agents; Moths; Sepharose; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 1991 |
Interleukin-2 nephrotoxicity assessed in vitro.
Topics: Animals; Cell Division; Cells, Cultured; Dexamethasone; Interleukin-2; Kidney; Kidney Diseases; Swine; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1991 |
Oxidative stress and tumour cell proliferation.
Topics: Animals; Antigens, Polyomavirus Transforming; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; Culture Media; Fibroblasts; Free Radicals; HeLa Cells; Hydrogen Peroxide; Mesocricetus; Oncogene Protein p21(ras); Oxidation-Reduction; Oxygen; Paraquat; Rats; Superoxides; Tetrazolium Salts; Thiazoles; Vitamin E | 1990 |
[A tumor sensitivity test, SDI test using XTT].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Drug Screening Assays, Antitumor; Mice; Mice, Inbred Strains; Sarcoma 180; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
Application of the MTT colorimetric assay to measure cytotoxic effects of phenolic compounds on established rat dental pulp cells.
Topics: Animals; Biological Assay; Colorimetry; Coloring Agents; Dental Pulp; Dose-Response Relationship, Drug; Phenols; Rats; Tetrazolium Salts; Thiazoles | 1991 |
Selective cytotoxicity of N-nitrosamines to cultured rat esophageal epithelial cells.
Topics: Animals; Carcinogens; Cell Count; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Dimethylnitrosamine; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Esophagus; Male; Nitrosamines; Rats; Tetrazolium Salts; Thiazoles; Trypan Blue | 1991 |
Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production.
Topics: Carcinoma, Renal Cell; Cell Division; Cell Line; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Formazans; Glucose; Humans; Kidney Neoplasms; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; NAD; NADP; Tetrazolium Salts; Thiazoles | 1991 |
A quantitative microwell assay for chondrocyte cell adhesion.
Topics: Animals; Cartilage, Articular; Cattle; Cell Adhesion; Cell Division; Cells, Cultured; Colorimetry; Coloring Agents; Fibronectins; Formazans; Kinetics; Male; Sheep; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1991 |
Colorimetric assay for cellular activity in microcapsules.
Topics: Animals; Capsules; Cells, Cultured; Colorimetry; Coloring Agents; Cricetinae; Cricetulus; Fibroblasts; Formazans; Tetrazolium Salts; Thiazoles | 1990 |
MTT colorimetric assay detects mitogen responses of spleen but not blood lymphocytes.
Topics: Animals; Colorimetry; Coloring Agents; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oxidation-Reduction; Rats; Rats, Inbred Strains; Spleen; Tetrazolium Salts; Thiazoles; Thymidine | 1990 |
Quantification of proliferative and suppressive responses of human T lymphocytes following ConA stimulation.
Topics: Aging; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; CD8 Antigens; Cell Division; Cell Survival; Colorimetry; Concanavalin A; Female; Humans; Kinetics; Lymphocyte Activation; Male; Models, Biological; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles | 1990 |
Proliferation of human ocular fibroblasts. An assessment of in vitro colorimetric assays.
Topics: beta-N-Acetylhexosaminidases; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Evaluation Studies as Topic; Fibroblasts; Humans; Lysosomes; Mitochondria; Neutral Red; Plicamycin; Tetrazolium Salts; Thiazoles | 1990 |
A study of human small-cell lung carcinoma (hSCLC) cell lines with different sensitivities to detect relevant mechanisms of cisplatin (CDDP) resistance.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Cell Line; Cisplatin; Coloring Agents; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Humans; Lung Neoplasms; Organoplatinum Compounds; Platinum; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
Evaluation of a rapid tetrazolium-based colorimetric assay for selecting anticancer drugs.
Topics: Antineoplastic Agents; Colorimetry; Drug Screening Assays, Antitumor; Humans; Predictive Value of Tests; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1990 |
A simple and rapid method to determine hematopoietic growth factor activity.
Topics: Animals; Bone Marrow; Cells, Cultured; Colony-Stimulating Factors; Colorimetry; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoietic Cell Growth Factors; Interleukin-3; Mice; Mice, Inbred C57BL; Recombinant Proteins; Reproducibility of Results; Sepharose; Tetrazolium Salts; Thiazoles | 1990 |
[Is the estimation of the activity of MTT-reduction suitable for the determination of basal cytotoxicity?].
Topics: Animals; Aorta, Thoracic; Cattle; Cell Survival; Endothelium, Vascular; Formazans; Histocytochemistry; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1990 |
Biological effects of shock waves: cell disruption, viability, and proliferation of L1210 cells exposed to shock waves in vitro.
Topics: Animals; Cell Division; Cell Survival; Leukemia L1210; Lithotripsy; Tetrazolium Salts; Thiazoles; Trypan Blue; Tumor Cells, Cultured | 1990 |
Inhibition of ribonucleotide reductase and growth of human colon carcinoma HT-29 cells and mouse leukemia L1210 cells by N-hydroxy-N'-aminoguanidine derivatives.
Topics: Animals; Cell Division; Cell-Free System; Colonic Neoplasms; Guanidines; Humans; Leukemia L1210; Mice; Ribonucleotide Reductases; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
Characteristics of MTT as an indicator of viability and respiratory burst activity of human neutrophils.
Topics: Adult; Cell Survival; Female; Humans; Male; Neutrophils; Reference Standards; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 1990 |
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions.
Topics: Asparaginase; Cells, Cultured; Child; Coloring Agents; Culture Media; Cyclophosphamide; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Mechlorethamine; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thiazoles; Thioguanine; Vincristine | 1990 |
A quantitative colorimetric method to evaluate the functional state of human polymorphonuclear leukocytes.
Topics: Cell Division; Cell Survival; Humans; Hydrogen Peroxide; Neutrophils; Oxidation-Reduction; Oxygen; Tetrazolium Salts; Thiazoles | 1990 |
Use of the tetrazolium assay in measuring the response of human tumor cells to ionizing radiation.
Topics: Carcinoma, Transitional Cell; Cell Division; Cell Survival; Humans; Neuroblastoma; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1990 |
Effect of exposure to calcium entry blockers on doxorubicin accumulation and cytotoxicity in multidrug-resistant cells.
Topics: Calcium Channel Blockers; Cell Division; Coloring Agents; Doxorubicin; Drug Interactions; Drug Resistance; Flow Cytometry; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
A simple in vito cytotoxicity test using the MTT (3-(4,5)-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) colorimetric assay: analysis of eugenol toxicity on dental pulp cells (RPC-C2A).
Topics: Cell Survival; Cells, Cultured; Colorimetry; Dental Pulp; Eugenol; Formazans; Humans; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 1990 |
Specific killing of neuroblastoma cells in vitro by immunotoxins.
Topics: Antibodies, Monoclonal; Cell Survival; Coloring Agents; Humans; Immunotoxins; Neuroblastoma; Ricin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
Colorimetric glucose assay using thermostable glucokinase.
Topics: Blood Glucose; Colorimetry; Dithiothreitol; Enzyme Stability; Formazans; Geobacillus stearothermophilus; Glucokinase; Hexokinase; Hot Temperature; Kinetics; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 1990 |
[SDI test using MTT for the evaluation of drug sensitivities of gastrointestinal cancer cells].
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Gastrointestinal Neoplasms; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Subrenal Capsule Assay; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1990 |
Mechanism for 193-nm laser radiation-induced effects on mammalian cells.
Topics: Animals; Arachidonic Acids; Cell Line; Cell Membrane; Cells, Cultured; Cricetinae; Cricetulus; DNA; Lasers; Mice; Mice, Inbred C3H; Tetrazolium Salts; Thiazoles | 1990 |
Evaluation of tetrazolium-based semiautomatic colorimetric assay for measurement of human antitumor cytotoxicity.
Topics: Carcinoma, Squamous Cell; Cell Adhesion; Cell Count; Cell Survival; Chromium Radioisotopes; Colorimetry; Evaluation Studies as Topic; Head and Neck Neoplasms; Humans; Immunity, Cellular; Killer Cells, Lymphokine-Activated; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1990 |
Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay.
Topics: Antineoplastic Agents; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Leukemia; Predictive Value of Tests; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1990 |
Towards an optimized MTT assay.
Topics: 1-Propanol; Cytotoxicity Tests, Immunologic; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocyte Activation; Sodium Dodecyl Sulfate; Solubility; Tetrazolium Salts; Thiazoles | 1990 |
Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Pilot Projects; Protein Binding; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Xanthenes | 1990 |
Human multi-drug-resistant cancer cells exhibit a high degree of selectivity for stereoisomers of verapamil and quinidine.
Topics: Cell Line; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; HeLa Cells; Humans; Neoplasms; Quinidine; Stereoisomerism; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 1990 |
[Significance of tetrazolium salt based colorimetric assay (MTT assay) for isolated rabbit parietal cell].
Topics: Animals; Cell Survival; Colorimetry; Parietal Cells, Gastric; Rabbits; Temperature; Tetrazolium Salts; Thiazoles | 1990 |
MTT colorimetric assay for testing macrophage cytotoxic activity in vitro.
Topics: Animals; Colorimetry; Coloring Agents; Cytotoxicity Tests, Immunologic; Female; Macrophages; Mice; Mice, Inbred C57BL; Tetrazolium Salts; Thiazoles | 1990 |
A rapid colorimetric assay of fungal viability with the tetrazolium salt MTT.
Topics: Fungi; Humans; Hydrogen Peroxide; Leukocytes; Mycology; Oxidation-Reduction; Spectrophotometry; Spores, Fungal; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1985 |
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cell Line, Transformed; Colorimetry; Cytopathogenic Effect, Viral; Dextran Sulfate; Dextrans; Dideoxynucleosides; Drug Evaluation, Preclinical; Heparin; HIV; Humans; Tetrazolium Salts; Thiazoles; Zalcitabine; Zidovudine | 1988 |
Detection of activated lymphocyte subsets by fluorescence and MTT staining.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Cyclosporins; Humans; In Vitro Techniques; Lymphocyte Activation; Receptors, Interleukin-2; Receptors, Transferrin; Staining and Labeling; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors | 1989 |
A rapid and simple colorimetric test for the study of anti-HIV agents.
Topics: Antiviral Agents; Cell Line; Colorimetry; Cytopathogenic Effect, Viral; Formazans; HIV; Humans; Microbial Sensitivity Tests; Ribavirin; RNA-Directed DNA Polymerase; Tetrazolium Salts; Thiazoles; Virus Replication; Zidovudine | 1988 |
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill.
Topics: Animals; Buffers; Cell Count; Cell Division; Cell Line; Cell Survival; Coloring Agents; Formazans; Hydrogen-Ion Concentration; Kinetics; Mice; Reproducibility of Results; Spectrophotometry; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1989 |
Tetrazolium-based plaque assay for HIV-1 and HIV-2, and its use in the evaluation of antiviral compounds.
Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV-1; HIV-2; Pentosan Sulfuric Polyester; Staining and Labeling; Stavudine; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Zidovudine | 1989 |
The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Colony-Forming Units Assay; Cricetinae; Drug Screening Assays, Antitumor; Mitomycin; Mitomycins; Oxygen; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tirapazamine; Triazines | 1989 |
[A study of MTT-hybrid assay using human bone and soft tissue tumor cells].
Topics: Antineoplastic Agents; Bone Neoplasms; Drug Screening Assays, Antitumor; Humans; Soft Tissue Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
The MTT assay underestimates the growth inhibitory effects of interferons.
Topics: Cell Count; Cell Line; Colorimetry; Coloring Agents; Culture Media; Formazans; Humans; Hydrogen-Ion Concentration; Interferon Type I; Lung Neoplasms; Receptors, Immunologic; Receptors, Interferon; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1989 |
Chemosensitivity and radiosensitivity of small cell lung cancer cell lines studied by a newly developed 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) hybrid assay.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cell Division; Cisplatin; Colony-Forming Units Assay; Drug Resistance; Humans; Lung Neoplasms; Predictive Value of Tests; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Identification of anthracyclines and related agents that retain preferential activity over adriamycin in multidrug-resistant cell lines, and further resistance modification by verapamil and cyclosporin A.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Small Cell; Cell Line; Coloring Agents; Cyclosporins; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 1989 |
In-vitro effects of cilofungin (LY121019), amphotericin B and amphotericin B-deoxycholate on human polymorphonuclear leucocytes.
Topics: Amphotericin B; Antifungal Agents; Calcium; Chemotaxis; Deoxycholic Acid; Drug Combinations; Echinocandins; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Neutrophils; Peptides; Peptides, Cyclic; Phagocytosis; Superoxides; Tetrazolium Salts; Thiazoles | 1989 |
[Chemosensitivity testing on human bladder cancer cell lines, using MTT-assay].
Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Colorimetry; Drug Screening Assays, Antitumor; Humans; Hyperthermia, Induced; Predictive Value of Tests; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1989 |
The further application of MTT-formazan colorimetry to studies on filarial worm viability.
Topics: Animals; Brugia; Colorimetry; Coloring Agents; Dipetalonema; Female; Filaricides; Filarioidea; Formazans; Kinetics; Male; Onchocerca; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1989 |
Characterization of a human tumour cell line panel for screening of anti-tumour agents in vitro.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1989 |
Specific assays for cytokine production by T cells.
Topics: Animals; Antibodies, Monoclonal; Biological Assay; Biological Factors; Colorimetry; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-2; Interleukin-4; Interleukins; Lymphocyte Activation; Mice; RNA, Messenger; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1989 |
Monosialoganglioside GM1 protects against anoxia-induced neuronal death in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Coloring Agents; G(M1) Ganglioside; Gangliosides; Hypoxia; Microscopy, Phase-Contrast; Neurons; Nitrogen; Rotenone; Tetrazolium Salts; Thiazoles | 1989 |
Predictability of in vivo chemosensitivity by in vitro MTT assay with reference to the clonogenic assay.
Topics: Animals; Cell Survival; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Predictive Value of Tests; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay.
Topics: Azo Compounds; Buffers; Cell Count; Coloring Agents; Culture Media; Doxorubicin; Drug Screening Assays, Antitumor; Formazans; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Oxidation-Reduction; Spectrum Analysis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1989 |
Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia.
Topics: Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid, Acute; Tetrazolium Salts; Thiazoles | 1989 |
Levels of the 90kd heat shock protein and resistance to glucocorticoid-mediated cell killing in a range of human and murine lymphocyte cell lines.
Topics: Animals; Cell Division; Cell Line; Coloring Agents; Dexamethasone; Drug Resistance; Glucocorticoids; Heat-Shock Proteins; Humans; Lymphocytes; Mice; Molecular Weight; Tetrazolium Salts; Thiazoles | 1989 |
Comparison of tetrazolium colorimetric and [3H]-uridine assays for in vitro chemosensitivity testing.
Topics: Carcinoma; Cell Line; Colonic Neoplasms; Colorimetry; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Immunoglobulin G; Immunotoxins; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tritium; Tumor Cells, Cultured; Uridine; Uterine Cervical Neoplasms; Vindesine | 1989 |
Toxic interactions between carbon tetrachloride and chloroform in cultured rat hepatocytes.
Topics: Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Membrane; Cells, Cultured; Chloroform; Choline; Coloring Agents; Drug Interactions; Endoplasmic Reticulum; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Phosphatidylcholines; Rats; Rats, Inbred Strains; Tetrazolium Salts; Thiazoles | 1989 |
[Evaluation of predictability of in vitro SDI assay in comparison with in vivo nude mouse assay].
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Drug Screening Assays, Antitumor; Fibroblasts; Gastrointestinal Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Predictive Value of Tests; Reproducibility of Results; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1989 |
The radiation dose to cells in vitro from intracellular indium-111.
Topics: Animals; Cell Line; Cell Nucleus; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Indium Radioisotopes; Radiation Dosage; Tetrazolium Salts; Thiazoles | 1989 |
The levels of nicotinamide nucleotides in liver microsomes and their possible significance to the function of hexose phosphate dehydrogenase.
Topics: Animals; Carbohydrate Dehydrogenases; Glucose-6-Phosphatase; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Phenazines; Rats; Tetrazolium Salts; Thiazoles | 1987 |
Chemosensitivity testing of human lung cancer cell lines using the MTT assay.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
In vitro antitumor activity of mitomycin C derivative (RM-49) and new anticancer antibiotics (FK973) against lung cancer cell lines determined by tetrazolium dye (MTT) assay.
Topics: Antibiotics, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Count; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mitomycins; Oxazines; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1988 |
Growth factor effects on small cell lung cancer cells using a colorimetric assay: can a transferrin-like factor mediate autocrine growth?
Topics: Carcinoma, Small Cell; Cell Division; Culture Media; Estradiol; Growth Substances; Humans; Hydrocortisone; Insulin; Lung Neoplasms; Selenium; Spectrophotometry; Tetrazolium Salts; Thiazoles; Transferrin; Tumor Cells, Cultured | 1988 |
Effect of erythromycin and tumour necrosis factor on the drug resistance of multidrug-resistant cells: reversal of drug resistance by erythromycin.
Topics: Animals; Antineoplastic Agents; Coloring Agents; Dactinomycin; Doxorubicin; Drug Interactions; Drug Resistance; Drug Synergism; Erythromycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Verapamil | 1989 |
On the suitability of the MTT-assay for the evaluation of mitogenic lymphocyte blastogenesis in swine.
Topics: Animals; Colorimetry; Coloring Agents; Lymphocyte Activation; Swine; Tetrazolium Salts; Thiazoles | 1989 |
Comparison of the rapid automated MTT-assay with a dye exclusion assay for chemosensitivity testing in childhood leukaemia.
Topics: Antineoplastic Agents; Cell Survival; Child; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1989 |
An assay for growth of mouse bone marrow cells in microtiter liquid culture using the tetrazolium salt MTT, and its application to studies of myelopoiesis.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hematopoiesis; Interleukin-3; Macrophage Colony-Stimulating Factor; Mice; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1988 |
Application of the MTT assay to human prostate cancer cell lines in vitro: establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects.
Topics: Androgens; Cell Count; Cell Division; Coloring Agents; Drug Screening Assays, Antitumor; Eflornithine; Estrenes; Humans; Male; Metribolone; Mitoguazone; Oxidation-Reduction; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
Agents that mimic antigen receptor signaling inhibit proliferation of cloned murine T lymphocytes induced by IL-2.
Topics: Animals; Cells, Cultured; Clone Cells; Drug Combinations; Drug Synergism; Ethers; Growth Inhibitors; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Inbred DBA; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1988 |
A rapid colorimetric assay for the determination of IL-2-producing helper T cell frequencies.
Topics: Animals; Colorimetry; Interleukin-2; Leukocyte Count; Mice; Mice, Inbred CBA; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tetrazolium Salts; Thiazoles | 1985 |
Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia.
Topics: Antineoplastic Agents; Cell Survival; Child; Colony-Forming Units Assay; Dimethyl Sulfoxide; Formazans; Humans; Leukemia, Lymphoid; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1988 |
A microtiter cell-culture assay for the determination of anti-human immunodeficiency virus neutralizing antibody activity.
Topics: Antibodies, Viral; Cell Line; Cell Survival; Coloring Agents; HIV; HIV Antibodies; Neutralization Tests; Tetrazolium Salts; Thiazoles | 1988 |
Cytotoxic effect of T-2 mycotoxin on cells in culture as determined by a rapid colorimetric bioassay.
Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Colorimetry; Humans; Insecta; Lymphocytes; Rabbits; Rats; Sesquiterpenes; Species Specificity; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1988 |
Sodium succinate enhances the colorimetric reaction of the in vitro chemosensitivity test: MTT assay.
Topics: Animals; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Male; Mice; Sarcoma 180; Succinate Dehydrogenase; Succinates; Succinic Acid; Tetrazolium Salts; Thiazoles | 1988 |
Use of the MTT assay for rapid determination of chemosensitivity of human leukemic blast cells.
Topics: Antineoplastic Agents; Blast Crisis; Cell Survival; Drug Resistance; Formazans; Humans; Microchemistry; Neoplastic Stem Cells; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
Optimization of the tetrazolium-based colorimetric assay for the measurement of cell number and cytotoxicity.
Topics: Animals; Cell Count; Cell Survival; Colorimetry; Daunorubicin; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
BCGFLMW-sensitivity of human B-cell lines in the MTT-cleavage assay.
Topics: B-Lymphocytes; Cell Line; Colorimetry; DNA Replication; Humans; Indicators and Reagents; Interleukin-2; Interleukin-4; Interleukins; Molecular Weight; Tetrazolium Salts; Thiazoles | 1988 |
Drug metabolite toxicity assessed in human lymphocytes with a purified, reconstituted cytochrome P-450 system.
Topics: Acetaminophen; Animals; Cell Survival; Cytochrome P-450 Enzyme System; Glutathione; Glutathione Transferase; Humans; Lymphocytes; Male; NADP; Pyridines; Rats; Tetrazolium Salts; Thiazoles | 1988 |
Cellular effects of T-2 mycotoxin on two different cell lines.
Topics: Animals; Binding Sites; Cattle; Cell Line; Cells; Chromium Radioisotopes; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Eukaryotic Cells; Female; Mitochondria; Ovary; Protein Synthesis Inhibitors; Sesquiterpenes; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1988 |
Use of a tetrazolium based colorimetric assay in assessing photoradiation therapy in vitro.
Topics: Blood; Cell Line; Cell Survival; Colony-Forming Units Assay; Colorimetry; Formazans; Humans; Photochemotherapy; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 1988 |
Use of a colorimetric microtiter (MTT) assay in determining the radiosensitivity of cells from murine solid tumors.
Topics: Animals; Cell Survival; Colorimetry; Coloring Agents; Mice; Neoplasms, Experimental; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1988 |
Colorimetric microtiter plate assay of glucose and fructose by enzyme-linked formazan production: applicability to the measurement of fructosyl transferase activity in higher plants.
Topics: beta-Fructofuranosidase; Colorimetry; Formazans; Fructose; Glucose; Glycoside Hydrolases; Hexosyltransferases; Plants; Tetrazolium Salts; Thiazoles | 1987 |
An improved colorimetric assay for interleukin 2.
Topics: Cells, Cultured; Colorimetry; Detergents; Humans; Interleukin-2; Solubility; Tetrazolium Salts; Thiazoles; Tritium | 1986 |
A colorimetric method for measuring the candidacidal activity of leucocytes.
Topics: Animals; Candida albicans; Colorimetry; Culture Media; Female; Mice; Neutrophils; Tetrazolium Salts; Thiazoles | 1986 |
[Application of tetrazolium bromide to an in vitro chemosensitivity test].
Topics: Cell Division; Colony-Forming Units Assay; Humans; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 1987 |
Cytotoxicity of oxidative metabolites of procainamide.
Topics: Ascorbic Acid; Blood Physiological Phenomena; Cell Line; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Humans; Hydroxylamine; Hydroxylamines; Lymphocyte Activation; NAD; Oxidation-Reduction; Procainamide; Tetrazolium Salts; Thiazoles | 1987 |
A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Coloring Agents; Culture Media; Dimethyl Sulfoxide; Drug Evaluation, Preclinical; Formazans; Mice; Neoplasms, Experimental; Optics and Photonics; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 1987 |
Detection of the lethal effects of T-2 mycotoxin on cells using a rapid colorimetric viability assay.
Topics: Animals; Cell Survival; Cells, Cultured; Colorimetry; DNA; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Protein Biosynthesis; Sesquiterpenes; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1987 |
Rapid chemosensitivity testing of human lung tumor cells using the MTT assay.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Drug Resistance; Humans; Lung Neoplasms; Oxidation-Reduction; Spectrophotometry; Tetrazolium Salts; Thiazoles | 1986 |
Comparison of in vitro activity of cytotoxic drugs towards human carcinoma and leukaemia cell lines.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cell Count; Cell Line; Cell Survival; Colonic Neoplasms; Humans; Kinetics; Leukemia; Tetrazolium Salts; Thiazoles | 1986 |
Use of MTT colorimetric assay to measure cell activation.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Colorimetry; DNA; Kinetics; Mitochondria; Rats; Tetrazolium Salts; Thiazoles | 1986 |
Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.
Topics: Animals; Antineoplastic Agents; Autoanalysis; Cell Line; Cisplatin; Clone Cells; Colorimetry; Coloring Agents; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Humans; In Vitro Techniques; Lung Neoplasms; Melphalan; Tetrazolium Salts; Thiazoles; Vinblastine | 1987 |
Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity.
Topics: Animals; Autoanalysis; Bromodeoxyuridine; Cell Line; Clone Cells; Colorimetry; Coloring Agents; Cricetinae; Cricetulus; Cysteamine; Humans; Lung Neoplasms; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Time Factors | 1987 |
Improved in vitro determination of the viability of Taenia saginata embryos.
Topics: Animals; Coloring Agents; Culture Media; Embryo, Nonmammalian; Methods; Taenia; Tetrazolium Salts; Thiazoles | 1985 |
Interaction of interleukin 2 with cells: quantitative analysis of effects.
Topics: Animals; Cell Cycle; Cell Line; Dose-Response Relationship, Immunologic; Growth Substances; Interleukin-2; Lymphocyte Activation; Mathematics; Mice; Mice, Inbred CBA; Models, Biological; Oxidation-Reduction; Reference Standards; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1985 |
Study of a time lag in the assay of Escherichia coli membrane-bound dehydrogenases based on tetrazolium salt reduction.
Topics: Escherichia coli; Kinetics; L-Lactate Dehydrogenase; Membranes; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 1985 |
A one-plate assay for macrophage bactericidal activity.
Topics: Blood Bactericidal Activity; Colorimetry; Coloring Agents; Humans; Immunologic Techniques; Interferon-gamma; Listeria monocytogenes; Macrophages; Oxidation-Reduction; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 1985 |
Bilirubin toxicity in neural cell lines N115 and NBR10A.
Topics: Animals; Bilirubin; Cell Line; Cell Survival; DNA; Mice; Neuroblastoma; Neurons; Rats; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1985 |
Lymphoblastic transformation assay of sheep peripheral blood lymphocytes: a new rapid and easy-to-read technique.
Topics: Animals; Cell Division; Cell Survival; Colorimetry; Concanavalin A; DNA; Female; Lymphocyte Activation; Lymphocytes; Lymphocytes, Null; Male; Mitogens; Phytohemagglutinins; Pokeweed Mitogens; Sheep; Tetrazolium Salts; Thiazoles; Thymidine | 1985 |
Diaphorase P: a new fetal isozyme identified in human placenta.
Topics: Carcinoma, Hepatocellular; Cytosol; Dihydrolipoamide Dehydrogenase; Electrophoresis, Starch Gel; Erythrocytes; Female; Fetus; Hot Temperature; Humans; Isoenzymes; Liver Neoplasms; Placenta; Pregnancy; Tetrazolium Salts; Thiazoles; Tissue Distribution | 1980 |
A technically simple "non-lethal" vital staining procedure for viral plaque and cell transformation assays. Brief report.
Topics: Cell Transformation, Viral; Microbiological Techniques; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 1984 |
Effect of auto-oxidized phospholipids on oxidative enzyme assays based on tetrazolium salt reduction.
Topics: Edetic Acid; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; NAD; Oxidation-Reduction; Phosphatidylcholines; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 1983 |
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.
Topics: Animals; Cell Line; Cell Survival; Colorimetry; Concanavalin A; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Immunologic; Interleukin-2; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Lymphoma; Macrophage Activation; Mice; Mice, Inbred BALB C; Tetrazolium Salts; Thiazoles | 1983 |
Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines.
Topics: Animals; Antilymphocyte Serum; Cell Line; Cell Survival; Colorimetry; Coloring Agents; Cytotoxicity, Immunologic; Humans; Killer Factors, Yeast; Lymphokines; Lymphotoxin-alpha; Mice; Neutralization Tests; Oxidation-Reduction; Proteins; Tetrazolium Salts; Thiazoles | 1984 |
Effect of phospholipids, triton X-100 and biological membranes on redox systems involving tetrazolium salt reduction. its implications for the assay of enzymatic activities.
Topics: Animals; Erythrocyte Membrane; Erythrocytes; Kinetics; L-Lactate Dehydrogenase; Liposomes; NAD; Octoxynol; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Polyethylene Glycols; Rats; Spectrophotometry; Tetrazolium Salts; Thiazoles | 1982 |
Expression of type I interleukin-1 receptor mRNA and its regulation in cultured astrocytes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Blotting, Northern; Bucladesine; Cells, Cultured; Coloring Agents; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Humans; Interleukin-1; Isoproterenol; Propranolol; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Interleukin-1; Recombinant Proteins; RNA, Messenger; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 1995 |
Investigation of cytotoxic effects of 8 norbornane derivatives on 4 human cancer cell lines using the MTT assay.
Topics: Antineoplastic Agents; Cell Division; Coloring Agents; HL-60 Cells; Humans; Norbornanes; Solubility; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Comparison of [3H]thymidine incorporation with MTT- and MTS-based bioassays for human and murine IL-2 and IL-4 analysis. Tetrazolium assays provide markedly enhanced sensitivity.
Topics: Animals; Biological Assay; Cell Line; Colorimetry; Humans; Interleukin-2; Interleukin-4; Lymphocytes; Mice; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1995 |
Protective effects of calcium channel blockers against free radical-impaired endothelial cell proliferation.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Cattle; Cell Division; Cell Survival; Colorimetry; Endothelium, Vascular; Nicardipine; Reactive Oxygen Species; Stereoisomerism; Tetrazolium Salts; Thiazoles | 1995 |
Rapamycin but not FK506 inhibits the proliferation of mononuclear phagocytes induced by colony-stimulating factors.
Topics: Animals; Bone Marrow Cells; Cell Count; Cell Division; Colony-Stimulating Factors; Concanavalin A; Culture Media, Conditioned; Cyclosporine; Female; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phagocytes; Polyenes; Sirolimus; Spleen; T-Lymphocytes; Tacrolimus; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1994 |
The development and characterization of an eluted stain assay (ESTA) for the insulin-like growth factors.
Topics: Adult; Animals; Antibodies, Monoclonal; Biological Assay; Blotting, Western; Carrier Proteins; Cell Count; Cell Line; Female; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Male; Pregnancy; Rats; Rats, Inbred F344; Somatomedins; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1993 |
A colourimetric dye assay to detect anti-viral activity of interferons: sensitivity for measuring cellular responsiveness to interferons.
Topics: Cell Division; Cell Survival; Colorimetry; Humans; Interferons; Melanoma; Semliki forest virus; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Amyloid beta protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid beta protein.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cell Death; Cells, Cultured; Cerebral Cortex; Hippocampus; Neurons; Peptide Fragments; Rats; Substance P; Tetrazolium Salts; Thiazoles | 1994 |
Comparison of the cytotoxic and antiretroviral effects of 3-nitrosobenzamide and 4-iodo-3-nitrobenzamide.
Topics: Antiviral Agents; B-Lymphocytes; Benzamides; Cell Line; Cell Survival; Coloring Agents; Humans; Nitroso Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Retroviridae; RNA-Directed DNA Polymerase; Simian Immunodeficiency Virus; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Virus Replication | 1994 |
A rapid colorimetric assay for carcinoembryonic antigen (CEA)-mediated cell adhesion and analysis of CEA domains involved in the adhesion.
Topics: Animals; Antibodies, Monoclonal; Binding Sites; Carcinoembryonic Antigen; Cell Adhesion; Cell Count; Cell Survival; Cells, Cultured; CHO Cells; Colorimetry; Cricetinae; DNA, Neoplasm; Epitopes; Humans; Tetrazolium Salts; Thiazoles; Transfection | 1994 |
Super-sensitive epithelial cell line and colorimetric assay to replace the conventional K562 target and chromium release assay for assessment of non-MHC-restricted cytotoxicity.
Topics: Cell Death; Colorimetry; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Epithelium; Female; Humans; Interferons; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Male; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1995 |
Induction of functional interleukin-2 receptor in mouse microglia.
Topics: Animals; Antibodies; Base Sequence; Bromodeoxyuridine; Cells, Cultured; Gene Expression; Interleukin-2; Lipopolysaccharides; Mice; Microglia; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Interleukin-2; Recombinant Proteins; RNA-Directed DNA Polymerase; RNA, Messenger; Tetrazolium Salts; Thiazoles | 1995 |
Localization of damage induced by reactive oxygen species in cultured cells.
Topics: Aminoisobutyric Acids; Animals; Benzene Derivatives; Biological Transport, Active; Cell Line; Cell Membrane; Glucose; Hybridomas; Hydrogen Peroxide; Mice; Mitochondria; Oxidopamine; Rats; Reactive Oxygen Species; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1995 |
The development of an eluted stain bioassay (ESTA) for human growth hormone.
Topics: Animals; Biological Assay; Fetal Blood; Formazans; Growth Hormone; Humans; Lymphoma; Macromolecular Substances; Rats; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Beta-amyloid inhibition of MTT reduction is not mimicked by inhibitors of mitochondrial respiration.
Topics: Allopurinol; Amyloid beta-Peptides; Animals; Antimycin A; Antineoplastic Agents; Cisplatin; Coloring Agents; Deoxyglucose; Dicumarol; Doxorubicin; Humans; Mitochondria; Oxazines; Oxidation-Reduction; Oxygen Consumption; PC12 Cells; Peptide Fragments; Rats; Rotenone; Tetrazolium Salts; Thiazoles; Xanthenes | 1995 |
Inhibition of tumor cell growth by a human B-cell line.
Topics: Adenocarcinoma; Antigens, CD20; B-Lymphocytes; Breast Neoplasms; Cell Survival; Coloring Agents; Herpesvirus 4, Human; Humans; Immunity, Cellular; Killer Cells, Lymphokine-Activated; Leukemia, Hairy Cell; Lymphocytes, Tumor-Infiltrating; Polymerase Chain Reaction; Receptors, Antigen, B-Cell; Receptors, Interleukin-2; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Cytotoxic effects of several hopanoids on mouse leukemia L1210 and P388 cells.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Leukemia L1210; Leukemia P388; Membrane Fluidity; Mice; Mice, Inbred DBA; Oxygen Consumption; Tetrazolium Salts; Thiazoles; Triterpenes | 1995 |
In vitro modulation of preleukemic AKR mouse macrophage function by bacterial immunomodulators.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Cell Movement; Female; Formazans; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred AKR; Mitochondria; Peptidoglycan; Preleukemia; Spleen; Tetrazolium Salts; Thiazoles | 1995 |
Nonradioactive alternative to clinical mixed lymphocyte reaction.
Topics: Cells, Cultured; Colorimetry; Coloring Agents; Humans; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Spectrophotometry; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1995 |
A simplified new assay for assessment of fungal cell damage with the tetrazolium dye, (2,3)-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanil ide (XTT).
Topics: Aspergillus fumigatus; Cytotoxicity Tests, Immunologic; Humans; Microbiological Techniques; Neutrophils; Oxidation-Reduction; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 1995 |
Sinugibberol, a new cytotoxic cembranoid diterpene from the soft coral Sinularia gibberosa.
Topics: Animals; Antineoplastic Agents; Cnidaria; Crystallography, X-Ray; Diterpenes; Drug Screening Assays, Antitumor; Fourier Analysis; Humans; Leukemia P388; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Sphingosine: a mediator of acute renal tubular injury and subsequent cytoresistance.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Calcium; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Fibroblasts; Humans; Ionophores; Kidney Tubules, Proximal; Male; Penis; Remission, Spontaneous; Sphingosine; Tetrazolium Salts; Thiazoles | 1995 |
[Chemosensitivity test for thyroid cancer by in vitro MTT assay].
Topics: Antineoplastic Agents; Cisplatin; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Middle Aged; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured | 1995 |
Effect of selenium on malignant tumor cells of brain.
Topics: Animals; Anticarcinogenic Agents; Brain Neoplasms; Cell Death; Cell Division; Glioblastoma; Glioma; Humans; Rats; Selenium; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Child; Coloring Agents; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lymphocytes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Androgens inhibit the proliferation of a variant of the human prostate cancer cell line LNCaP.
Topics: Amino Acid Sequence; Androgens; Base Sequence; Cell Division; Coloring Agents; Dihydrotestosterone; DNA, Neoplasm; Epidermal Growth Factor; Exons; Fibroblast Growth Factor 2; Humans; Male; Metribolone; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Point Mutation; Prostatic Neoplasms; Receptors, Androgen; Testosterone Congeners; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Phenytoin inhibits expression of microtubule-associated protein 2 and influences cell-viability and neurite growth of cultured cerebellar granule cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Cytoskeleton; Depression, Chemical; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurites; Neurons; Phenytoin; Tetrazolium Salts; Thiazoles | 1995 |
In vitro skin irritancy: application of keratinocytes cell culture and its correlation with human patch test responses.
Topics: Cell Death; Cells, Cultured; Coloring Agents; Dermatitis, Irritant; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Irritants; Keratinocytes; L-Lactate Dehydrogenase; Patch Tests; Skin; Tetrazolium Salts; Thiazoles | 1995 |
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells.
Topics: Apoptosis; Caffeine; Carboplatin; Cluster Analysis; Coloring Agents; Daunorubicin; Drug Resistance, Neoplasm; Flow Cytometry; G2 Phase; Gamma Rays; Gene Expression Regulation, Leukemic; Glutathione; GTP-Binding Proteins; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Multivariate Analysis; Oncogene Proteins v-fos; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; ras Proteins; S Phase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Quantitative multiwell myeloid differentiation assay using dichlorodihydrofluorescein diacetate (H2DCF-DA) or dihydrorhodamine 123 (H2R123).
Topics: Calibration; Cell Differentiation; Fluoresceins; Fluorescent Dyes; Fluorometry; Granulocytes; HL-60 Cells; Humans; Monocytes; Oxidation-Reduction; Respiratory Burst; Rhodamines; Tetrazolium Salts; Thiazoles | 1995 |
A biochemical evaluation of oral squamous cell carcinoma growth by measurement of specific activity of succinate dehydrogenase in the subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Peplomycin; Regression Analysis; Subrenal Capsule Assay; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1995 |
Suppression of mitochondrial succinate dehydrogenase, a primary target of beta-amyloid, and its derivative racemized at Ser residue.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain Chemistry; Cell Survival; Hippocampus; Mitochondria; Neurons; Oxidation-Reduction; Rats; Rats, Wistar; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tissue Extracts | 1995 |
Effects of selenium on UVA-induced lipid peroxidation in cultured human skin fibroblasts.
Topics: Adolescent; Adult; Catalase; Cells, Cultured; Culture Media; Female; Fibroblasts; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Middle Aged; Selenium; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays | 1995 |
Reversal of multidrug resistance by novel cyclosporin A analogues and the cyclopeptolide SDZ 214-103 biosynthesized in vitro.
Topics: Cyclosporins; Dactinomycin; Doxorubicin; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Friend murine leukemia virus; Humans; Immunosuppressive Agents; Leukemia, Erythroblastic, Acute; Lymphoma; Rhodamine 123; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Decreased energy charge of peripheral blood lymphocytes in septic patients after hepatic resection.
Topics: Aged; Aged, 80 and over; Arteries; Blood Cells; Energy Metabolism; Female; Hepatectomy; Humans; Infections; Ketone Bodies; Lymphocytes; Male; Middle Aged; Postoperative Complications; Tetrazolium Salts; Thiazoles | 1995 |
Determination of MICs for Mycobacterium avium-M. intracellulare complex in liquid medium by a colorimetric method.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biological Transport, Active; Clofazimine; Colorimetry; Dipeptides; Fluoroquinolones; Glycerol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Oxidation-Reduction; Quinolones; Radiometry; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 1995 |
[Significance of cancer cell purification determining chemosensitivities for gastric cancer cells].
Topics: Antineoplastic Agents; Cell Separation; Centrifugation; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Inhibitory effect of natural interferon alpha on human immunodeficiency virus type 1 transmission from epithelial cells to lymphocytes in vitro.
Topics: Acquired Immunodeficiency Syndrome; Cell Adhesion; Cell Line; Epithelium; HIV Reverse Transcriptase; HIV-1; Humans; Interferon-alpha; Lymphocytes; RNA-Directed DNA Polymerase; Tetrazolium Salts; Thiazoles | 1993 |
Comparison of the neutral red and methylene blue assays to study cell growth in culture.
Topics: Cell Division; Cells, Cultured; DNA; Female; Fluorometry; Humans; Methylene Blue; Neutral Red; Ovary; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1993 |
Measurement of cell numbers in microtiter culture plates using the fluorescent dye Hoechst 33258.
Topics: Adrenal Medulla; Animals; Bisbenzimidazole; Cattle; Cell Count; Cells, Cultured; DNA; Endothelium; Reproducibility of Results; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 1993 |
A new method for the detection of viable cells in tissue sections using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT): an application in the assessment of tissue damage by surgical instruments.
Topics: Animals; Cell Survival; Coloring Agents; Electrocoagulation; Histocytochemistry; Laser Therapy; Mice; Mice, Inbred BALB C; Staining and Labeling; Surgical Instruments; Tetrazolium Salts; Thiazoles | 1993 |
In vitro chemosensitivity test for human genitourinary tumors using collagen gel matrix.
Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Survival; Collagen; Drug Screening Assays, Antitumor; Fibrin Foam; Humans; In Vitro Techniques; Tetrazolium Salts; Thiazoles; Urogenital Neoplasms | 1993 |
Enhanced chemosensitivity in acute myeloid leukemia by hematopoietic growth factors: a comparison of the MTT assay with a clonogenic assay.
Topics: Adult; Aged; Antineoplastic Agents; Bromodeoxyuridine; Clone Cells; Colorimetry; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Male; Middle Aged; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 1993 |
Effects of granulocyte colony stimulating factor and monobactam antibiotics (Aztreonam) on neutrophil functions in sepsis.
Topics: Animals; Aztreonam; Cell Adhesion; Chemotaxis, Leukocyte; Coloring Agents; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Leukocyte Count; Male; Neutrophils; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Tetrazolium Salts; Thiazoles | 1993 |
Drug combination testing in acute lymphoblastic leukemia using the MTT assay.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Daunorubicin; Drug Interactions; Drug Resistance; Humans; In Vitro Techniques; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1995 |
[Chemosensitivity test with endoscopic biopsy specimens].
Topics: Animals; Antineoplastic Agents; Biopsy; Drug Screening Assays, Antitumor; Endoscopy, Gastrointestinal; Humans; Intestinal Neoplasms; Neoplasms, Experimental; Sensitivity and Specificity; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of beta-amyloid in rat PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Coloring Agents; Glycosaminoglycans; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles | 1995 |
Use of lactate dehydrogenase to evaluate the anti-viral activity against influenza A virus.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Colorimetry; Coloring Agents; Cytidine; Dogs; Guanine; Influenza A virus; L-Lactate Dehydrogenase; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Tetrazolium Salts; Thiazoles | 1995 |
Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance.
Topics: B-Lymphocytes; Chlorambucil; Cisplatin; Cross-Linking Reagents; DNA Adducts; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Humans; Inactivation, Metabolic; Leukemia, Lymphocytic, Chronic, B-Cell; Melphalan; Methyl Methanesulfonate; Mitomycin; Nitrogen Mustard Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Cytotoxicity of mycotoxins evaluated by the MTT-cell culture assay.
Topics: Animals; Antifungal Agents; Cell Death; Cells, Cultured; Dogs; HeLa Cells; Humans; Kidney; Mycotoxins; Swine; Tetrazolium Salts; Thiazoles | 1994 |
Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay.
Topics: Amphotericin B; Aspergillus fumigatus; Candida albicans; Dose-Response Relationship, Drug; Fluconazole; Formazans; Itraconazole; Microbial Sensitivity Tests; Mitochondria; Tetrazolium Salts; Thiazoles; Vitamin K | 1995 |
Gamma irradiation effects on cultured cells: investigated by the MTT method.
Topics: Cell Count; Female; Gamma Rays; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1994 |
Glycosaminoglycans and sulphated polyanions attenuate the neurotoxic effects of beta-amyloid.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Coloring Agents; Congo Red; Dose-Response Relationship, Drug; Glycosaminoglycans; Neurotoxins; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles | 1995 |
Cytotoxicity of ether phospholipid BM 41.440 on neuroblastoma cells.
Topics: Antineoplastic Agents; Hematopoietic Stem Cells; Humans; Neuroblastoma; Phospholipid Ethers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Evidence that cell survival is controlled by interleukin-3 independently of cell proliferation.
Topics: Animals; Azides; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Division; Cell Survival; Cytochalasin B; DNA; Doxorubicin; Interleukin-3; Mice; Mice, Inbred C3H; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Protein Kinase Inhibitors; Sodium Azide; Tetrazolium Salts; Thiazoles | 1995 |
The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.
Topics: Amyloid beta-Peptides; Animals; Cell Membrane Permeability; Coloring Agents; HeLa Cells; Humans; Intracellular Membranes; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles | 1995 |
Growth conditions differentially modulate the vulnerability of developing cerebellar granule cells to excitatory amino acids.
Topics: Animals; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Excitatory Amino Acids; GABA Agonists; GABA Antagonists; Glutamic Acid; Immunohistochemistry; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrazolium Salts; Thiazoles | 1994 |
In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Central Nervous System Neoplasms; Glioma; Gossypol; Humans; Isoenzymes; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Rats; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Enhancement of ACNU cytotoxicity by pretreatment with O6-methylguanine in ACNU-resistant brain tumors.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Densitometry; Drug Resistance; Drug Synergism; Guanine; Humans; Male; Neoplasm Transplantation; Nimustine; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1994 |
Teleocidins and benzolactams inhibit cell killing by human immunodeficiency virus type 1 (HIV-1).
Topics: Antiviral Agents; Coloring Agents; Cytopathogenic Effect, Viral; HIV-1; Humans; Irritants; Lyngbya Toxins; Tetrazolium Salts; Thiazoles; Virus Replication; Viruses | 1994 |
A sensitive assay system screening antiviral compounds against herpes simplex virus type 1 and type 2.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cell Survival; Coloring Agents; Embryo, Mammalian; Formazans; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Kinetics; Lung; Microbial Sensitivity Tests; Sensitivity and Specificity; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors; Viral Plaque Assay | 1994 |
Docosahexaenoic acid, a major constituent of fetal serum and fish oil diets, inhibits IFN gamma-induced Ia-expression by murine macrophages in vitro.
Topics: Animals; Cells, Cultured; Docosahexaenoic Acids; Female; Fetal Blood; Histocompatibility Antigens Class II; Indomethacin; Interferon-gamma; Interleukin-4; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Serum Albumin; Tetrazolium Salts; Thiazoles | 1995 |
A possible mechanism for the cytotoxicity of a polyacetylenic alcohol, panaxytriol: inhibition of mitochondrial respiration.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alkynes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Enediynes; Fatty Alcohols; Humans; Microscopy, Electron; Mitochondria; Oxygen; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Characterisation of oxidative injury to an intestinal cell line (HT-29) by hydrogen peroxide.
Topics: Adenosine Triphosphate; Catalase; Cell Survival; Dose-Response Relationship, Drug; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Intestinal Mucosa; Kinetics; Lethal Dose 50; Oxidative Stress; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Cytotoxicity tests of antibacterial agents on human fibroblasts cultures.
Topics: Cell Survival; Cells, Cultured; Coloring Agents; Female; Fibroblasts; Humans; Preservatives, Pharmaceutical; Tetrazolium Salts; Thiazoles | 1994 |
Caprine arthritis encephalitis virus infection changes caprine blood monocyte responsiveness to lipopolysaccharide stimulation in vitro.
Topics: Animals; Arthritis-Encephalitis Virus, Caprine; Cell Line; Female; Fibroblasts; Goat Diseases; Goats; Interleukin-1; Lentivirus Infections; Lipopolysaccharides; Mice; Monocytes; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1994 |
Structure-activity studies on 2-aryl-4H-3,1-benzoxazin-4-ones.
Topics: Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; KB Cells; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred DBA; Models, Molecular; Oxazines; Pancreatic Elastase; Structure-Activity Relationship; Swine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Inhibitory effects of the gastrin receptor antagonist CR2093 on basal, gastrin-stimulated and growth factor-stimulated growth of the rat pancreatic cell line AR42J.
Topics: Amino Acids; Animals; Cell Division; Coloring Agents; Epidermal Growth Factor; Gastrins; Growth Inhibitors; Growth Substances; Humans; Iodine Radioisotopes; Pancreatic Neoplasms; Rats; Receptors, Cholecystokinin; Tetrazolium Salts; Thiazoles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1994 |
O6-alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications.
Topics: Astrocytoma; Brain Neoplasms; Combined Modality Therapy; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Glioblastoma; Glioma; Humans; Methyltransferases; Neoplasm Proteins; Neoplasm Recurrence, Local; Nimustine; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Tetrazolium Salts; Thiazoles | 1994 |
Effect of disruption of actin filaments by Clostridium botulinum C2 toxin on insulin secretion in HIT-T15 cells and pancreatic islets.
Topics: Actin Cytoskeleton; Actins; Animals; Bombesin; Botulinum Toxins; Calcium; Cell Line; Cell Size; Colforsin; Cytochalasins; Exocytosis; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Microscopy, Fluorescence; Oxidation-Reduction; Rats; Tetrazolium Salts; Thiazoles | 1994 |
Neurotrophin-4/5 promotes survival and differentiation of rat striatal neurons developing in culture.
Topics: Animals; Blotting, Western; Calbindin 2; Cell Differentiation; Cell Survival; Cells, Cultured; DNA; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Neostriatum; Nerve Growth Factors; Neurons; Phosphatidylinositols; Rats; Recombinant Proteins; S100 Calcium Binding Protein G; Tetrazolium Salts; Thiazoles | 1994 |
[[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity.
Topics: Antiviral Agents; Cytopathogenic Effect, Viral; HeLa Cells; Humans; Oxazoles; Rhinovirus; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 1995 |
Activated THP-1 cells depress mitochondrial respiration in Hep G2 cells infected with influenza B virus.
Topics: Animals; Cell Membrane Permeability; Cell Survival; Chick Embryo; Humans; Influenza B virus; Iron; Lipopolysaccharides; Liver; Macrophage Activation; Macrophages; Mitochondria; Reye Syndrome; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Virus Replication | 1994 |
Characterisation of the influence of anti-gastrin, anti-epidermal growth factor, anti-oestradiol, and anti-luteinising hormone releasing hormone antibodies on the proliferation of 27 cell lines from the gastrointestinal tract.
Topics: Animals; Antibodies; Cell Division; Cell Line; Coloring Agents; Digestive System; Dose-Response Relationship, Immunologic; Epidermal Growth Factor; Estradiol; Gastrins; Gonadotropin-Releasing Hormone; Growth Substances; Guinea Pigs; Humans; Mice; Rats; Tetrazolium Salts; Thiazoles | 1995 |
Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts.
Topics: Antibodies; Apoptosis; Cell Nucleus; Cells, Cultured; DNA; Female; Flow Cytometry; Humans; Interferon-gamma; Pregnancy; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Trophoblasts; Tumor Necrosis Factor-alpha | 1994 |
Comparison of ketoconazole- and fluconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes.
Topics: Analysis of Variance; Animals; Cell Membrane Permeability; Cells, Cultured; Fluconazole; Ketoconazole; L-Lactate Dehydrogenase; Liver; Lysosomes; Mitochondria, Liver; Neutral Red; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1995 |
Purification and quantification of Fusobacterium necrophorum leukotoxin by using monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Antigens, Bacterial; Bacterial Toxins; Binding, Competitive; Cattle; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Exotoxins; Fusobacterium necrophorum; Mice; Neutralization Tests; Neutrophils; Tetrazolium Salts; Thiazoles | 1994 |
Effect of thiram on chick chondrocytes in culture.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Chickens; Coloring Agents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Growth Plate; L-Lactate Dehydrogenase; Molecular Weight; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Thiram | 1995 |
Toxicity evaluation of the mycotoxins, citrinin and ochratoxin A, using several animal cell lines.
Topics: Alkaline Phosphatase; Animals; Cell Line; Cell Survival; Citrinin; Colorimetry; Dogs; Humans; Lethal Dose 50; Leucyl Aminopeptidase; Mice; Mycotoxins; Ochratoxins; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1993 |
CD4 but not CD8 is comodulated with the T-cell antigen receptor (TCR) after activation of a CD4+ CD8+ human leukemia line with staphylococcal enterotoxin.
Topics: Antibodies, Monoclonal; Antigens, Surface; CD3 Complex; CD4-Positive T-Lymphocytes; Enterotoxins; Humans; Interleukin-2; Lymphocyte Activation; Mitogens; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
In vitro assessment of the ethanol-induced hepatotoxicity on HepG2 cell line.
Topics: Analysis of Variance; Aspartate Aminotransferases; Cell Line; Cell Nucleus; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Ethanol; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Humans; Kinetics; L-Lactate Dehydrogenase; Liver; Microscopy, Electron; Microvilli; Mitochondria, Liver; Tetrazolium Salts; Thiazoles | 1993 |
Modification by brefeldin A, bafilomycin A1 and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD) of cellular accumulation and intracellular distribution of anthracyclines in the non-P-glycoprotein-mediated multidrug-resistant cell line COR-L23/R.
Topics: 4-Chloro-7-nitrobenzofurazan; Anti-Bacterial Agents; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brefeldin A; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Nucleus; Cyclopentanes; Cytoplasm; Daunorubicin; Doxorubicin; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Golgi Apparatus; Humans; Lung Neoplasms; Macrolides; Membrane Glycoproteins; Protein Synthesis Inhibitors; Proton-Translocating ATPases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
[Group A streptococcal polysaccharide--an inhibitor of the functional activity of T-suppressors induced by Con A in a culture of mononuclear cells of human peripheral blood].
Topics: Adult; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Coloring Agents; Concanavalin A; Humans; Immunophenotyping; Leukocytes, Mononuclear; Polysaccharides, Bacterial; Reference Values; Streptococcus pyogenes; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles | 1993 |
Modulation of cisplatin cytotoxicity by sulphasalazine.
Topics: Carcinoma, Small Cell; Cisplatin; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Glutathione Transferase; Humans; Isoenzymes; Lung Neoplasms; Sulfasalazine; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Anti-proliferative activity of interferon-alpha on human squamous carcinoma of tongue cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cisplatin; Combined Modality Therapy; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Interferon Type I; Kinetics; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Tumor Cells, Cultured | 1994 |
Comparative toxicity of tetracaine, proparacaine and cocaine evaluated with primary cultures of rabbit corneal epithelial cells.
Topics: Anesthetics, Local; Animals; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Endothelium, Corneal; L-Lactate Dehydrogenase; Mitochondria; Propoxycaine; Rabbits; Tetracaine; Tetrazolium Salts; Thiazoles; Time Factors | 1994 |
Cytotoxicity of gallium and indium ions compared with mercuric ion.
Topics: Animals; Cell Count; Cell Division; Cell Line; Colorimetry; Coloring Agents; Fibroblasts; Gallium; Indium; Mercury; Mercury Compounds; Mice; Microscopy, Electron, Scanning; Mitochondria; Nitrates; Oxidoreductases; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 1994 |
The hepatotoxicities of endotoxin and ethanol comparisons in vitro using the precision-cut rat liver slice model.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endotoxins; Ethanol; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1994 |
Pyridazine analogs of piperidinylbenzophenone immunomodulators. 70th communication: syntheses and reactions of pyridazines.
Topics: Adjuvants, Immunologic; Animals; Benzophenones; Cell Division; Cell Survival; Coloring Agents; Mice; Pyridazines; Spleen; Tetrazolium Salts; Thiazoles; Thymidine | 1994 |
6-Allyl-5,6-dihydro-5-hydroxypyran-2-one, a lactone produced by a new Drechslera species: specified 1H and 13C NMR assignments, mutagenic and immunomodulating testings.
Topics: Adjuvants, Immunologic; Animals; Chromatography, High Pressure Liquid; Dogs; In Vitro Techniques; Macrophages; Magnetic Resonance Spectroscopy; Mice; Mitosporic Fungi; Mutagenicity Tests; Mutagens; Pyrones; Rats; Salmonella typhimurium; Tetrazolium Salts; Thiazoles | 1994 |
Adaptation of the diphenylamine (DPA) assay to a 96-well plate tissue culture format and comparison with the MTT assay.
Topics: Animals; Cell Division; Diphenylamine; DNA; Rats; Rats, Sprague-Dawley; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Quantitative in vitro assessment of phototoxicity using a human skin model, Skin2.
Topics: Benzophenones; Cell Survival; Coloring Agents; Culture Techniques; Dermatitis, Phototoxic; Epidermal Cells; Fibroblasts; Humans; Irritants; Keratinocytes; Models, Biological; Promethazine; Skin; Tetracycline; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 1994 |
Stimulation of GABAergic neuron differentiation by NT-4/5 in cultures of rat cerebral cortex.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Calbindins; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Rats; S100 Calcium Binding Protein G; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 1994 |
A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro.
Topics: Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioma; Humans; Tamoxifen; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 1994 |
Comparison of cell proliferation and toxicity assays using two cationic liposomes.
Topics: Bromodeoxyuridine; Cations; Cell Death; Cell Division; Coloring Agents; DNA; Fatty Acids, Monounsaturated; Fluorescent Dyes; Humans; L-Lactate Dehydrogenase; Liposomes; Mitochondria; Quaternary Ammonium Compounds; Tetrazolium Salts; Thiazoles; Thymidine; Trypan Blue; Tumor Cells, Cultured | 1994 |
The role of glutathione and protein thiols in CBrCl3-induced cytotoxicity in isolated rat hepatocytes.
Topics: Animals; Bromotrichloromethane; Cell Survival; Dose-Response Relationship, Drug; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Potassium; Proteins; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 1994 |
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay.
Topics: Cell Separation; Child; Drug Resistance; Humans; Immunomagnetic Separation; In Vitro Techniques; Leukocytes, Mononuclear; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Improved automatic kinetic method for the determination of various corticosteroids.
Topics: Adrenal Cortex Hormones; Chemistry, Pharmaceutical; Indicators and Reagents; Kinetics; Tetrazolium Salts; Thiazoles | 1994 |
MTT colorimetric assay system for the screening of anti-orthomyxo- and anti-paramyxoviral agents.
Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Colorimetry; Coloring Agents; Cytidine; Dogs; HeLa Cells; Humans; Influenza A virus; Measles virus; Microbial Sensitivity Tests; Orthomyxoviridae; Pyrazoles; Respiratory Syncytial Viruses; Respirovirus; Ribavirin; Ribonucleosides; Ribose; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Vero Cells; Virus Replication | 1994 |
The identification of drug resistance in ovarian cancer and breast cancer: application of the MTT assay.
Topics: Adenocarcinoma; Breast Neoplasms; Colorimetry; Coloring Agents; Drug Resistance; Drug Screening Assays, Antitumor; Feasibility Studies; Female; Humans; Neoplasm Staging; Ovarian Neoplasms; Pilot Projects; Predictive Value of Tests; Prognosis; Tetrazolium Salts; Thiazoles | 1994 |
Measurement of radiation survival using the MTT assay.
Topics: Cell Survival; Dose-Response Relationship, Radiation; Humans; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Lymphocyte stimulation test with tetrazolium-based colorimetric assay for diagnosis of drug-induced allergic hepatitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Colorimetry; Drug Hypersensitivity; Female; Humans; Infant; Infant, Newborn; Lymphocyte Activation; Male; Middle Aged; Tetrazolium Salts; Thiazoles | 1994 |
A microplate-based bioassay system for measuring porcine serum mitogenic activity.
Topics: Animals; Biological Assay; Cell Count; Cell Division; Cell Line; Clone Cells; Coloring Agents; Creatine Kinase; Mitogens; Muscle, Skeletal; Muscle, Smooth; Swine; Tetrazolium Salts; Thiazoles | 1994 |
Air samples from a building with asbestos-containing material: asbestos content and in vitro toxicity on rat pleural mesothelial cells.
Topics: Air Pollution, Indoor; Animals; Asbestos; Asbestos, Crocidolite; Asbestos, Serpentine; Cell Survival; Cells, Cultured; DNA; DNA Repair; Mutagens; Pleura; Rats; Tetrazolium Salts; Thiazoles | 1994 |
A modified invasion-3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide assay for quantitating tumor cell invasion.
Topics: Animals; Collagen; Colorimetry; Coloring Agents; Diffusion Chambers, Culture; Drug Combinations; Erythrocytes; Humans; Laminin; Mice; Neoplasm Invasiveness; Proteoglycans; Tetrazolium Salts; Thiazoles; Vero Cells | 1994 |
A colorimetric assay method for the evaluation of neurotrophic activity in vitro.
Topics: Acid Phosphatase; Animals; Cell Survival; Cells, Cultured; Colorimetry; Culture Media, Serum-Free; Fibroblast Growth Factor 2; Mice; Mice, Inbred Strains; Neurons; Tetrazolium Salts; Thiazoles | 1994 |
MTT-assay and neutral red release (NRR)-assay: relative role in the prediction of the irritancy potential of surfactants.
Topics: Adult; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Double-Blind Method; Female; Humans; Irritants; Male; Middle Aged; Neutral Red; Skin; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Toxicology | 1994 |
Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons--a possible novel pathogenetic mechanism in Parkinson's disease.
Topics: Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Chick Embryo; Coloring Agents; DNA Damage; Dopamine; Flow Cytometry; Neurons; Parkinson Disease; Sympathetic Nervous System; Tetrazolium Salts; Thiazoles | 1994 |
A tetrazolium-based(MTT) assay for measuring viability of cultured porcine corneal endothelium.
Topics: Animals; Cell Survival; Cells, Cultured; Cornea; Endothelium; Tetrazolium Salts; Thiazoles | 1993 |
A rapid colorimetric assay of killer toxin activity in yeast.
Topics: Candida; Colorimetry; Formazans; Killer Factors, Yeast; Microbial Sensitivity Tests; Mycotoxins; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Time Factors | 1994 |
Single-cell suspension assay with an MTT end point is useful for evaluating the optimal adjuvant chemotherapy for advanced gastric cancer.
Topics: Adult; Aged; Chemotherapy, Adjuvant; Cisplatin; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; In Vitro Techniques; Male; Middle Aged; Mitomycin; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Tetrazolium Salts; Thiazoles | 1994 |
Detection of soft-tissue infections and osteomyelitis using a technetium-99m-labeled anti-granulocyte monoclonal antibody fragment.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Chemotaxis, Leukocyte; Female; Granulocytes; Humans; Infections; Male; Middle Aged; Nitroblue Tetrazolium; Organotechnetium Compounds; Osteomyelitis; Oximes; Phagocytosis; Radionuclide Imaging; Technetium Tc 99m Exametazime; Tetrazolium Salts; Thiazoles | 1994 |
Biological effectiveness of 67-gallium decay in HL60 cells compared with external low dose rate gamma irradiation: effects on proliferation, G2 arrest, and clonogenic capacity.
Topics: Cell Count; Cell Cycle; Cell Division; Clone Cells; Colony-Forming Units Assay; Dose-Response Relationship, Radiation; G2 Phase; Gallium; Gallium Radioisotopes; Humans; Leukemia, Promyelocytic, Acute; Radiation Dosage; Radiotherapy Planning, Computer-Assisted; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia.
Topics: Acute Disease; Colorimetry; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Immunologic Techniques; In Vitro Techniques; Leukemia, Myeloid; Monocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.
Topics: Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Flavonoids; Humans; Leucine; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Lignans; Lymphocyte Activation; Lymphocytes; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; Uridine | 1994 |
Localization of HIV RNA in mitochondria of infected cells: potential role in cytopathogenicity.
Topics: Cell Line; Coloring Agents; Cytopathogenic Effect, Viral; HIV-1; In Situ Hybridization; In Situ Hybridization, Fluorescence; Microscopy, Electron; Mitochondria; RNA, Messenger; RNA, Viral; Tetrazolium Salts; Thiazoles | 1994 |
Platelet-derived growth factor promotes survival of rat and human mesencephalic dopaminergic neurons in culture.
Topics: Animals; Cell Survival; Cells, Cultured; Dopamine; Female; Humans; Immunohistochemistry; Mesencephalon; Neurites; Neurons; Platelet-Derived Growth Factor; Pregnancy; Rats; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 1993 |
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Cell Death; Dose-Response Relationship, Drug; Humans; Molecular Sequence Data; NAD; NADP; Neurons; Oxidation-Reduction; PC12 Cells; Rats; Species Specificity; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Time Factors | 1994 |
The characterization of two human cervical carcinoma HeLa sublines resistant to cisplatin.
Topics: Antineoplastic Agents; Cell Separation; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; HeLa Cells; Humans; Metallothionein; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
A rapid colorimetric assay for evaluating Legionella pneumophila growth in macrophages in vitro.
Topics: Animals; Colorimetry; Deferoxamine; Electron Transport; Female; Formazans; Iron; Legionella pneumophila; Macrophages; Mice; Mice, Inbred Strains; Tetrazolium Salts; Thiazoles | 1994 |
Primary culture of rat gastric epithelial cells as an in vitro model to evaluate antiulcer agents.
Topics: Acids; Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Coloring Agents; Drug Evaluation, Preclinical; Epithelial Cells; Gastric Mucosa; Indomethacin; Microscopy, Phase-Contrast; Neutral Red; Rats; Rats, Sprague-Dawley; Sucralfate; Sucrose; Tetrazolium Salts; Thiazoles | 1994 |
Cytostatic and cytotoxic activity of sex steroids against human leukemia cell lines.
Topics: Androgens; Antineoplastic Agents; Diethylstilbestrol; Estrogens; Glucocorticoids; Gonadal Steroid Hormones; Humans; Leukemia; Neoplasms, Hormone-Dependent; Progesterone; Steroids; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Induction of glioma cell death by 1,25(OH)2 vitamin D3: towards an endocrine therapy of brain tumors?
Topics: Animals; Brain Neoplasms; Calcitriol; Cell Death; Glial Fibrillary Acidic Protein; Glioma; Humans; Rats; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Evaluation of the MTT and SRB assays for testing LAK cell-mediated growth inhibition of various adherent and non-adherent tumor target cells.
Topics: Cell Adhesion; Cell Division; Coloring Agents; Cytotoxicity, Immunologic; Humans; Killer Cells, Lymphokine-Activated; Oxidation-Reduction; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Chemoluminescence generation and MTT dye reduction by polymorphonuclear leukocytes from periodontal disease patients.
Topics: Adolescent; Adult; Aggressive Periodontitis; Case-Control Studies; Enzyme Activation; Female; Humans; Luminescent Measurements; Male; Neutrophils; Opsonin Proteins; Periodontitis; Phagocytosis; Protein Kinase C; Respiratory Burst; Superoxides; Tetrazolium Salts; Thiazoles; Zymosan | 1994 |
Rapid colorimetric bioassay for screening of Fusarium mycotoxins.
Topics: Animals; Biological Assay; Cells, Cultured; Colorimetry; Cricetinae; Fusarium; Mycotoxins; Tetrazolium Salts; Thiazoles; Trichothecenes | 1993 |
Rapid assessment of islet cell viability by MTT assay after cold storage in different solutions.
Topics: Adenosine; Allopurinol; Animals; Cell Survival; Cold Temperature; Coloring Agents; Disaccharides; Glutathione; Histidine; Insulin; Islets of Langerhans; Isotonic Solutions; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Strains; Solutions; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Preservation | 1994 |
A rapid mechanism-based screen to detect potential anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Survival; CHO Cells; Coloring Agents; Cricetinae; DNA Repair; Drug Screening Assays, Antitumor; Marine Toxins; Tetrazolium Salts; Thiazoles; Topoisomerase II Inhibitors | 1994 |
Concentration and sequence dependent synergism of ethyldeshydroxy-sparsomycin in combination with antitumor agents.
Topics: Animals; Antineoplastic Agents; Coloring Agents; Drug Antagonism; Drug Synergism; Melanoma, Experimental; Mice; Sparsomycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1994 |
Comparison of irritant potential of shampoos using cultured human epidermal keratinocytes model and patch test reaction measured by laser Doppler flowmetry.
Topics: Adult; Cells, Cultured; Coloring Agents; Dermatitis, Irritant; Epidermal Cells; Epidermis; Hair Preparations; Humans; Irritants; Keratinocytes; L-Lactate Dehydrogenase; Laser-Doppler Flowmetry; Male; Patch Tests; Skin; Tetrazolium Salts; Thiazoles | 1994 |
The role of DT-diaphorase in determining the sensitivity of human tumor cells to tirapazamine (SR 4233).
Topics: Antineoplastic Agents; Humans; NAD(P)H Dehydrogenase (Quinone); Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tirapazamine; Triazines; Tumor Cells, Cultured | 1994 |
Toxic effects of human pancreatic and snake and bee venom phospholipases A2 on MCF-7 cells in culture.
Topics: Animals; Bee Venoms; Cell Survival; Coloring Agents; Humans; Pancreas; Phospholipases A; Phospholipases A2; Snake Venoms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
In vitro assays for antitumour activity: more pitfalls to come?
Topics: Animals; Drug Screening Assays, Antitumor; Estrogens, Non-Steroidal; Genistein; Isoflavones; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival.
Topics: Animals; Breast Neoplasms; Cell Count; Formazans; Genistein; Growth Inhibitors; Humans; Isoflavones; Mitochondria; Mitosis; Protein-Tyrosine Kinases; Rhodamines; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Oxysterols inhibit gap junctional communication between rat hepatocytes in primary culture.
Topics: Animals; Cell Communication; Cells, Cultured; Cholesterol; Hydroxycholesterols; Intercellular Junctions; Ketocholesterols; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1993 |
Naphthalene-induced cytotoxicity on the hepatopancreatic cells of the red swamp crayfish, Procambarus clarkii.
Topics: Animals; Astacoidea; Cell Survival; Liver; Naphthalenes; Oxidoreductases; Pancreas; Tetrazolium Salts; Thiazoles | 1993 |
Characterization of the differentiation of human colorectal cancer cell lines by means of Voronoi diagrams.
Topics: Adenocarcinoma; Analog-Digital Conversion; Animals; Blood Physiological Phenomena; Cattle; Cell Death; Cell Differentiation; Cell Division; Cell Nucleus; Clone Cells; Colorectal Neoplasms; Colorimetry; Culture Media; Culture Media, Serum-Free; Humans; Image Processing, Computer-Assisted; Models, Theoretical; S Phase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Cellularly generated active oxygen species and HeLa cell proliferation.
Topics: Allopurinol; Catalase; Cell Division; Ditiocarb; HeLa Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxypurinol; Reactive Oxygen Species; Salicylates; Signal Transduction; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles; Xanthine Oxidase | 1993 |
The effect of food chemicals on cell aging of human diploid cells in in vitro culture.
Topics: Aflatoxin B1; Animals; Aspartame; Canavanine; Cattle; Cell Division; Cells, Cultured; Cellular Senescence; Fibroblasts; Food Analysis; Glucosephosphate Dehydrogenase; Humans; Isothiocyanates; Tetrazolium Salts; Thiazoles | 1993 |
beta-Amyloid peptides induce degeneration of cultured rat microglia.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Cell Count; Cell Survival; Cells, Cultured; Coloring Agents; Microglia; Nerve Degeneration; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 1993 |
Biocompatibility of glass ionomer cements.
Topics: Animals; Biocompatible Materials; Bone and Bones; Cell Survival; Cells, Cultured; Colorimetry; Fibroblasts; Glass Ionomer Cements; Mice; Prostheses and Implants; Rats; Tetrazolium Salts; Thiazoles | 1993 |
[A trial of isolation in chemotherapy for gynecological malignant tumor by MTT assay].
Topics: Adult; Aged; Coloring Agents; Drug Screening Assays, Antitumor; Female; Humans; Middle Aged; Ovarian Neoplasms; Tetrazolium Salts; Thiazoles; Uterine Neoplasms | 1993 |
Cytotoxicity potential of surfactant mixtures evaluated by primary cultures of rabbit corneal epithelial cells.
Topics: Animal Testing Alternatives; Animals; Cells, Cultured; Coloring Agents; Cornea; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; L-Lactate Dehydrogenase; Male; Mitochondria, Liver; Oxidation-Reduction; Rabbits; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 1994 |
A colorimetric assay for trypanosome viability and metabolic function.
Topics: Animals; Cattle; Colorimetry; Coloring Agents; Cytokines; Male; Oxidation-Reduction; Rats; Tetrazolium Salts; Thiazoles; Trypanosoma brucei rhodesiense; Trypanosoma congolense | 1993 |
Determination of IL-2 and cytotoxicity of killer cells in MTT colorimetry.
Topics: Colorimetry; Cytotoxicity, Immunologic; Formazans; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukemia, B-Cell; Leukemia, T-Cell; Lymphocytes, Tumor-Infiltrating; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
An improved MTT assay using the electron-coupling agent menadione.
Topics: Animals; Colorimetry; Coloring Agents; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Drug; Macrophages; Mice; Mice, Inbred CBA; Oxidation-Reduction; Rats; Rats, Wistar; Spleen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin K | 1994 |
An in vitro model of cyclosporine-induced nephrotoxicity.
Topics: Alkaline Phosphatase; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fluoresceins; Fluorescent Dyes; Kidney Cortex; Kidney Diseases; L-Lactate Dehydrogenase; Mitochondria; Neutral Red; Pharmaceutical Vehicles; Polyethylene Glycols; Propidium; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1993 |
A comparison between two methods for measuring tumor necrosis factor in biological fluids.
Topics: Animals; Cell Survival; Humans; L Cells; Macrophages; Mice; Rats; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice.
Topics: Animals; Disease Models, Animal; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 1993 |
In vitro anti-human immunodeficiency virus activity of 2',3'-dideoxynucleosides and their effect on clonal growth of hemopoietic cells from human bone marrow.
Topics: Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cell Line; Clone Cells; Colorimetry; Dideoxynucleosides; Drug Resistance; Hematopoietic Stem Cells; HIV-1; HIV-2; Humans; Stem Cells; Tetrazolium Salts; Thiazoles; Zidovudine | 1993 |
[A comparative study of chemosensitivity tests in vitro for AUC-dependent drugs focusing on the usefulness of MTT assay with drug washout and additional incubation (M-MTT)].
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Rapid quantitative assays for corneal endothelial cell viability in vitro.
Topics: Animals; Azo Compounds; Biological Assay; Cattle; Cell Survival; Cells, Cultured; Coloring Agents; Detergents; Endothelium, Corneal; Humans; Photometry; Tetrazolium Salts; Thiazoles | 1993 |
Down-regulation of phosphatidylinositol response to BDNF and NT-3 in cultures of cortical neurons.
Topics: Animals; Blotting, Western; Carbazoles; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytarabine; Down-Regulation; Female; Humans; Hydrolysis; Immunohistochemistry; Indole Alkaloids; Nerve Growth Factors; Nerve Tissue Proteins; Neuroglia; Neurons; Neurotrophin 3; Phosphatidylinositols; Pregnancy; Protein Kinase C; Rats; Tetrazolium Salts; Thiazoles | 1993 |
Optimal conditions of chemotherapeutic sensitivity in K562 cell line using tetrazolium dye assay.
Topics: Antineoplastic Agents; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Prediction of chemotherapy response in human leukemia using in vitro chemosensitivity test.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Coloring Agents; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Prognosis; Tetrazolium Salts; Thiazoles | 1993 |
Transient early metabolic and functional hyperreactivity and late areactivity of lymphocytes in preleukemic AKR mice.
Topics: Animals; Female; Graft vs Host Reaction; Interleukin-1; Interleukin-2; Lymph Nodes; Male; Mice; Mice, Inbred AKR; Mice, Inbred C57BL; Mice, Inbred CBA; Preleukemia; Rats; Rats, Inbred Lew; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Thymus Gland | 1993 |
The (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium) colorimetric assay for the quantitation of Actinobacillus pleuropneumoniae cytotoxin.
Topics: Actinobacillus pleuropneumoniae; Animals; Cells, Cultured; Colorimetry; Coloring Agents; Cytotoxins; Immune Sera; Neutrophils; Regression Analysis; Reproducibility of Results; Swine; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1993 |
Actinobacillus pleuropneumoniae culture supernatants interfere with killing of Pasteurella multocida by swine pulmonary alveolar macrophages.
Topics: Actinobacillus pleuropneumoniae; Animals; Bacterial Toxins; Cells, Cultured; Cytotoxins; L-Lactate Dehydrogenase; Macrophages, Alveolar; Nitroblue Tetrazolium; Phagocytosis; Phagosomes; Specific Pathogen-Free Organisms; Swine; Tetrazolium Salts; Thiazoles | 1993 |
Responses of human glioblastoma cells to human natural tumor necrosis factor-alpha: susceptibility, mechanism of resistance and cytokine production studies.
Topics: Cell Division; Colony-Forming Units Assay; Coloring Agents; Cytokines; Dinoprostone; Drug Resistance; Glioma; Humans; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Infusions, Parenteral; Leucovorin; Male; Mice; Mice, Inbred Strains; Mice, Nude; Models, Biological; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction.
Topics: Animals; Antimycin A; Bone Marrow; Cell Line; Chloromercuribenzoates; Chlorpromazine; Coloring Agents; Cytochrome c Group; Electron Transport; Electron Transport Complex IV; Lysosomes; Mice; Mice, Inbred C3H; Mitochondria; NAD; NADP; Oxidation-Reduction; p-Chloromercuribenzoic Acid; Succinates; Succinic Acid; Tetrazolium Salts; Thenoyltrifluoroacetone; Thiazoles | 1993 |
Anti-proliferative effects of the arotinoid Ro 40-8757 on human cancer cell lines in vitro.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Kinetics; Lung Neoplasms; Morpholines; Neoplasms; Receptors, Estrogen; Retinoids; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured | 1993 |
Human small cell lung cancer cell lines express functional atrial natriuretic peptide receptors.
Topics: Atrial Natriuretic Factor; Base Sequence; Blotting, Southern; Carcinoma, Small Cell; Cell Division; Cyclic GMP; HeLa Cells; Humans; Iodine Radioisotopes; Lung Neoplasms; Molecular Sequence Data; Polymerase Chain Reaction; Radioimmunoassay; Receptors, Atrial Natriuretic Factor; Ribonucleases; RNA, Messenger; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Tumor Cells, Cultured | 1993 |
Reduction of a tetrazolium salt and superoxide generation in human tumor cells (HeLa).
Topics: Allopurinol; Anti-Infective Agents; Biphenyl Compounds; Coloring Agents; Culture Media; Culture Media, Serum-Free; Formazans; HeLa Cells; Humans; Kinetics; Onium Compounds; Oxidation-Reduction; Oxypurinol; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles; Vitamin E | 1993 |
A comparison of clonogenic, microtetrazolium and sulforhodamine B assays for determination of cisplatin cytotoxicity in human ovarian carcinoma cell lines.
Topics: Cell Survival; Cisplatin; Drug Screening Assays, Antitumor; Female; Humans; Ovarian Neoplasms; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1993 |
The colorimetric assay for swine lymphocyte blastogenesis.
Topics: Animals; Colorimetry; Coloring Agents; Concanavalin A; DNA; Kinetics; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Radioisotope Dilution Technique; Swine; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium | 1993 |
Diagnosis of drug allergy by the lymphocyte stimulation test with the MTT [3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay.
Topics: Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Male; Middle Aged; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Effects of CAMPATH-1 antibodies on the functional activity of monocytes and polymorphonuclear neutrophils.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens, CD; Antigens, Neoplasm; Candida albicans; CD52 Antigen; Cell Death; Colorimetry; Flow Cytometry; Glycoproteins; Humans; Immunoglobulin G; Immunoglobulin M; Monocytes; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1993 |
An improved MTT assay.
Topics: Animals; Cell Division; Cell Survival; Colorimetry; Cytological Techniques; Interleukin-2; Mice; Tetrazolium Salts; Thiazoles | 1993 |
Comparative analysis of using MTT and XTT in colorimetric assays for quantitating bovine neutrophil bactericidal activity.
Topics: Animals; Blood Bactericidal Activity; Cattle; Colorimetry; Neutrophils; Tetrazolium Salts; Thiazoles; Ubiquinone | 1993 |
Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Colorimetry; Formazans; Interleukin-2; Interleukin-3; Mice; Tetrazolium Salts; Thiazoles | 1993 |
Differentiating and antitumor activities of 1 alpha,25-dihydroxyvitamin D3 in vitro and 1 alpha-hydroxyvitamin D3 in vivo on human osteosarcoma.
Topics: Adolescent; Alkaline Phosphatase; Animals; Antineoplastic Agents; Bone Neoplasms; Calcitriol; Cell Transformation, Neoplastic; Cisplatin; Culture Media; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydroxycholecalciferols; Mice; Mice, Nude; Osteocalcin; Osteosarcoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
The role of intracellular free calcium mobilization in the mechanism of action of antitumour ether lipids SRI 62-834 and ET18-OMe.
Topics: Antineoplastic Agents; Calcium; Cell Membrane; Dose-Response Relationship, Drug; Furans; Humans; Phospholipid Ethers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Hypersensitivity of human testis-tumour cell lines to chemotherapeutic drugs.
Topics: Antineoplastic Agents; Coloring Agents; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Male; Testicular Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1993 |
T lymphocyte reactivity to glutamic acid-alanine-tyrosine in vitro does not reflect antibody response in vivo.
Topics: Amino Acid Sequence; Animals; Antibody Formation; Antigen-Presenting Cells; Cells, Cultured; Chickens; Coloring Agents; Lymphocyte Activation; Molecular Sequence Data; Peptides; Polymers; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1993 |
Inhibition of gentamicin uptake into cultured mouse proximal tubule epithelial cells by L-lysine.
Topics: Animals; Cell Line; Coloring Agents; Culture Media; Epithelium; Gentamicins; Kidney Tubules, Proximal; Lysine; Mice; Mice, Transgenic; Models, Biological; Tetrazolium Salts; Thiazoles | 1993 |
Mechanism(s) regulating inhibition of thymidylate synthase and growth by gamma-L-glutaminyl-4-hydroxy-3-iodobenzene, a novel melanin precursor, in melanogenic melanoma cells.
Topics: Animals; Biotransformation; Buthionine Sulfoximine; Cell Division; Glutamine; Glutathione; GTP Phosphohydrolases; Humans; Melanins; Melanoma; Methionine Sulfoximine; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Protein Precursors; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
Modulation of human mesangial cell behaviour by extracellular matrix components--the possible role of interstitial type III collagen.
Topics: Basement Membrane; Biocompatible Materials; Cell Division; Cell Movement; Cells, Cultured; Collagen; Drug Combinations; Extracellular Matrix Proteins; Glomerular Mesangium; Humans; Laminin; Proteoglycans; Tetrazolium Salts; Thiazoles | 1993 |
Isolation of cytotoxic Kupffer cells by a modified enzymatic assay: a methodological study.
Topics: Animals; Cell Separation; Cytotoxicity, Immunologic; Kupffer Cells; Male; Rats; Tetrazolium Salts; Thiazoles | 1993 |
A colorimetric assay to evaluate the immune reactivity of blood platelets based on the reduction of a tetrazolium salt.
Topics: Aspirin; Blood Platelets; Colorimetry; Cytotoxicity, Immunologic; Humans; Immunoglobulin E; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1993 |
Optimization of the L-M cell bioassay for quantitating tumor necrosis factor alpha in serum and plasma.
Topics: Animals; Biological Assay; Cattle; Cell Line; Dogs; Goats; Heparin; Horses; Hot Temperature; Mice; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1993 |
Cellular drug resistance profiles that might explain the prognostic value of immunophenotype and age in childhood acute lymphoblastic leukemia.
Topics: Aging; Antineoplastic Agents; Child; Child, Preschool; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Immunophenotyping; Infant; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prognosis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1993 |
Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine.
Topics: Coloring Agents; Culture Media; Drug Screening Assays, Antitumor; Humans; Leukemia-Lymphoma, Adult T-Cell; Methotrexate; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Tumor Cells, Cultured; Xanthine Oxidase | 1993 |
A new approach for measurement of cytotoxicity using colorimetric assay.
Topics: Cell Division; Cell Line; Cell Transformation, Viral; Colorimetry; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; DNA Replication; Humans; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 1993 |
[High clinical predictability of histoculture drug response assay (HDRA) for drug-sensitivity of cancer of the digestive organs].
Topics: Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Characterization of neutrophil activation by repeated injection of endotoxin in rabbits. Role of neutrophils in the generalized Shwartzman reaction.
Topics: Animals; Antibodies, Monoclonal; Cell Adhesion; Chemotaxis, Leukocyte; Endothelium; Endotoxins; Injections, Intravenous; Liver; Luminescent Measurements; Lung; Neutrophils; Rabbits; Shwartzman Phenomenon; Tetrazolium Salts; Thiazoles | 1993 |
Synthetic polymer derivatives as substrata for neuronal adhesion and growth.
Topics: Acrylamides; Animals; Axons; Cell Adhesion; Cell Division; Coloring Agents; Gels; Methacrylates; Molecular Structure; Neurons; Rats; Tetrazolium Salts; Thiazoles | 1993 |
Regulation of mitogen-driven lymphoreticular cell activation by human corneal cells and interleukin-1.
Topics: Animals; Cells, Cultured; Concanavalin A; Cornea; DNA Replication; Epithelium; Humans; Interleukin-1; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred C3H; Tetrazolium Salts; Thiazoles | 1993 |
Gallium-67 radiotoxicity in human U937 lymphoma cells.
Topics: Cell Division; Gallium Radioisotopes; Humans; Lymphoma, Large B-Cell, Diffuse; Neoplastic Stem Cells; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Yttrium Radioisotopes | 1993 |
Significance of in vitro attachment of human colon cancers to extracellular matrix proteins in experimental and clinical liver metastases.
Topics: Animals; Cell Adhesion; Cell Line; Colonic Neoplasms; Coloring Agents; Extracellular Matrix Proteins; Humans; Liver Neoplasms; Male; Mice; Mice, SCID; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
Vitreous body-derived mitogenic activity for retinal pigment epithelial cells. A further characterization.
Topics: Animals; Cattle; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Growth Substances; Humans; Molecular Weight; Pigment Epithelium of Eye; Swine; Tetrazolium Salts; Thiazoles; Vitreous Body | 1993 |
Comparison of antitumor activity of vitamins K1, K2 and K3 on human tumor cells by two (MTT and SRB) cell viability assays.
Topics: Antineoplastic Agents; Cell Survival; Drug Screening Assays, Antitumor; Glutathione; Humans; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin K | 1993 |
Influence of different growth factors on a rat choriocarcinoma cell line.
Topics: Animals; Cattle; Cell Differentiation; Cell Division; Choriocarcinoma; Colorimetry; Epidermal Growth Factor; ErbB Receptors; Fetal Blood; Growth Substances; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Rats; Receptors, Transferrin; Tetrazolium Salts; Thiazoles; Transferrin; Transforming Growth Factor beta; Trophoblasts; Tumor Cells, Cultured | 1993 |
Comparative study of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and tritiated thymidine in a chemosensitivity test using collagen gel matrix.
Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Collagen; Coloring Agents; Drug Evaluation, Preclinical; Gels; Humans; Mice; Organ Culture Techniques; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Urinary Bladder Neoplasms | 1993 |
An MTT-based method for the in vivo quantification of myotoxic activity of snake venoms and its neutralization by antibodies.
Topics: Animals; Antivenins; Creatine Kinase; Elapid Venoms; Mice; Muscles; Neutralization Tests; Tetrazolium Salts; Thiazoles | 1993 |
In vitro evaluation of cell/biomaterial interaction by MTT assay.
Topics: Biocompatible Materials; Cell Count; Cell Survival; Cells, Cultured; Colorimetry; Cyanoacrylates; Dimethylpolysiloxanes; Humans; Leukocytes, Mononuclear; Metals; Polymers; Silicones; Tetrazolium Salts; Thiazoles | 1993 |
Intensity of class I antigen expression on human tumour cell lines and its relevance to the efficiency of non-MHC-restricted killing.
Topics: Antigens, Neoplasm; Cell Death; Cytokines; Histocompatibility Antigens Class I; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Major Histocompatibility Complex; Neoplasms, Experimental; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 1993 |
Titration of human-bovine rotavirus reassortants using a tetrazolium-based colorimetric end-point dilution assay.
Topics: Animals; Antigens, Viral; Capsid; Capsid Proteins; Cattle; Cell Line; Chlorocebus aethiops; Colorimetry; Coloring Agents; Cytopathogenic Effect, Viral; Humans; Macaca mulatta; Reassortant Viruses; Rotavirus; Tetrazolium Salts; Thiazoles; Titrimetry; Vero Cells | 1995 |
Electron transport chain activity in normal and activated rat macrophages.
Topics: Animals; Cell Survival; Coloring Agents; Electron Transport; Kinetics; Liver; Macrophages; Macrophages, Peritoneal; Male; Oxidation-Reduction; Propionibacterium acnes; Rats; Rats, Inbred ACI; Reference Values; Respiratory Burst; Tetrazolium Salts; Thiazoles | 1995 |
Scanning electron microscopy and transmission electron microscopy aspects of synergistic antitumor activity of vitamin C - vitamin K3 combinations against human prostatic carcinoma cells.
Topics: Antineoplastic Agents; Ascorbic Acid; Carcinoma; Cell Membrane; Coloring Agents; Cytoskeleton; Drug Synergism; Drug Therapy, Combination; Humans; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin K | 1995 |
A screening system for antiviral compounds against herpes simplex virus type 1 using the MTT method with L929 cells.
Topics: Animals; Antiviral Agents; Cell Line; Coloring Agents; Connective Tissue; Connective Tissue Cells; Drug Evaluation, Preclinical; Formazans; Herpes Simplex; Herpesvirus 1, Human; Indicators and Reagents; Mice; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Time Factors | 1995 |
Eulicin inhibits human immunodeficiency virus infection and replication.
Topics: Antifungal Agents; Antiviral Agents; Cell Line; Coloring Agents; Guanidines; HIV-1; Humans; Molecular Structure; RNA-Directed DNA Polymerase; Tetrazolium Salts; Thiazoles; Virus Replication | 1995 |
HepG2 human hepatocarcinoma cells: an experimental model for photosensitization by endogenous porphyrins.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Flow Cytometry; Hematoporphyrins; Humans; Lasers; Models, Biological; Photosensitizing Agents; Phototherapy; Protoporphyrins; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1995 |
Poly(vinyl chloride) formulations: acute toxicity to cultured human cell lines.
Topics: Carcinoma, Hepatocellular; Cell Line, Transformed; Coloring Agents; Cytoplasm; Fibroblasts; Humans; Liver Neoplasms; Lung; Materials Testing; Organotin Compounds; Plasticizers; Polyvinyl Chloride; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Novel doxorubicin-monoclonal anti-carcinoembryonic antigen antibody immunoconjugate activity in vitro.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Carcinoembryonic Antigen; Cell Survival; Colonic Neoplasms; Doxorubicin; Humans; Immunotoxins; Sulfhydryl Reagents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Pharmacotoxicological applications of an equivalent dermis: three measurements of cytotoxicity.
Topics: Cells, Cultured; Fibroblasts; Humans; Interleukin-6; Irritants; L-Lactate Dehydrogenase; Oxidation-Reduction; Reagent Kits, Diagnostic; Skin; Tetrazolium Salts; Thiazoles | 1995 |
Development and intralaboratory evaluation of an in vitro human cell-based test to aid ocular irritancy assessments.
Topics: Animal Testing Alternatives; Cell Survival; Cells, Cultured; Epithelial Cells; Epithelium; Eye Diseases; Fibroblasts; Humans; Irritants; Keratinocytes; Neutral Red; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xenobiotics | 1995 |
Evaluation of the toxicological risk to humans of caulerpenyne using human hematopoietic progenitors, melanocytes, and keratinocytes in culture.
Topics: Cells, Cultured; Chlorophyta; Chromatography, High Pressure Liquid; Coloring Agents; Dose-Response Relationship, Drug; Eukaryota; Fetal Blood; Hematopoietic Stem Cells; Humans; Keratinocytes; Lethal Dose 50; Marine Toxins; Melanocytes; Neutral Red; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 1996 |
Anti-Tat MTT assay: a novel anti-HIV drug screening system using the viral regulatory network of replication.
Topics: Antiviral Agents; Base Sequence; Cell Line; Cinnamates; Colorimetry; Coloring Agents; DNA Primers; Drug Evaluation, Preclinical; Gene Products, tat; HIV-1; Humans; Hygromycin B; Molecular Sequence Data; tat Gene Products, Human Immunodeficiency Virus; Tetrazolium Salts; Thiazoles; Virus Replication | 1995 |
Toxicity of oxysterols to human monocyte-macrophages.
Topics: Cells, Cultured; Humans; Hydroxycholesterols; Macrophages; Monocytes; Tetrazolium Salts; Thiazoles | 1995 |
In vitro biocompatibility testing of polymers for orthopaedic implants using cultured fibroblasts and osteoblasts.
Topics: 3T3 Cells; Animals; Benzophenones; Biocompatible Materials; Carbon; Cell Division; Cells, Cultured; Cytosol; Epoxy Resins; Glutathione; Hip Prosthesis; Ketones; L-Lactate Dehydrogenase; Materials Testing; Mice; Osteoblasts; Polyethylene Glycols; Polymers; Prostheses and Implants; Proteins; Rats; Tetrazolium Salts; Thiazoles | 1995 |
Leflunomide interferes with pyrimidine nucleotide biosynthesis.
Topics: Animals; Concanavalin A; Female; Humans; Immunosuppressive Agents; In Vitro Techniques; Indicators and Reagents; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; PC12 Cells; Pyrimidine Nucleotides; Rats; Spleen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Applications of MTT assay to primary cultured rat hepatocytes.
Topics: Animals; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media; Glucocorticoids; Insulin; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1995 |
In vitro evaluation of the potential antitumor activity of an N-acridyl-pentanoyloxypyridine-2-thione derivative.
Topics: Acridines; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Leukemia L1210; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Comparison of tetrazolium colorimetric and 51Cr release assays for cytotoxicity determination of dental biomaterials.
Topics: Animals; Cell Survival; Cells, Cultured; Chromates; Chromium Radioisotopes; Colorimetry; Dental Materials; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Indicators and Reagents; L Cells; Mice; Reproducibility of Results; Sensitivity and Specificity; Sodium Compounds; Tetrazolium Salts; Thiazoles; Toxicity Tests | 1995 |
Cytotoxic, nuclear, and growth inhibitory effects of photodynamic drugs on pancreatic carcinoma cells.
Topics: Animals; Carcinoma, Ductal, Breast; Cell Division; Cell Survival; Cricetinae; DNA, Neoplasm; Indoles; Mesocricetus; Micronuclei, Chromosome-Defective; Micronucleus Tests; Organometallic Compounds; Pancreatic Neoplasms; Photochemotherapy; Porphyrins; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Evaluation of the relative cytotoxic effects of anticancer agents in serum-supplemented versus serum-free media using a tetrazolium colorimetric assay.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Colorimetry; Coloring Agents; Culture Media, Serum-Free; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
The MTT tetrazolium salt assay scrutinized: how to use this assay reliably to measure metabolic activity of cell cultures in vitro for the assessment of growth characteristics, IC50-values and cell survival.
Topics: Cell Division; Cell Line; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media; Culture Media, Serum-Free; Culture Techniques; Estradiol; Formazans; Humans; Kinetics; Metabolism; Reproducibility of Results; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1995 |
Cytotoxic effects of 1 alpha,25-dihydroxyvitamin D3 and synthetic vitamin D3 analogues on a glioma cell line.
Topics: Animals; Calcitriol; Calcium; Cell Death; Cholecalciferol; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression; Genes, myc; Glioma; Homeostasis; Hypercalcemia; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Coloring Agents; Dexamethasone; Drug Screening Assays, Antitumor; Female; Humans; In Vitro Techniques; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
CD95 (Fas/Apo-1)-induced apoptosis results in loss of glucose transporter function.
Topics: Antibodies, Monoclonal; Apoptosis; Biological Transport, Active; Cell Line; Deoxyglucose; fas Receptor; Humans; Kinetics; Monosaccharide Transport Proteins; Oxidation-Reduction; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1996 |
Beta-amyloid-induced cell toxicity: enhancement of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide-dependent cell death.
Topics: Amyloid beta-Peptides; Animals; Cell Death; Kinetics; Neurotoxins; PC12 Cells; Rats; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 1996 |
Reduction of MTT as an index of electropermeabilization in spermatozoa.
Topics: Animals; Cattle; Cell Membrane; Coloring Agents; Cryopreservation; Electroporation; Male; Oxidation-Reduction; Semen Preservation; Sperm Motility; Spermatozoa; Tetrazolium Salts; Thiazoles | 1996 |
[In vitro chemosensitivity test for seven undifferentiated thyroid carcinoma cell lines using MTT assay].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Methotrexate; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured; Vincristine | 1996 |
Effect of growth factors on growth of bovine parathyroid cells in serum-free medium.
Topics: Animals; Cattle; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Coloring Agents; Culture Media, Serum-Free; Drug Combinations; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Growth Substances; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Microscopy, Electron; Parathyroid Glands; Tetrazolium Salts; Thiazoles; Thymidine; Transforming Growth Factor alpha; Tritium | 1996 |
An in vitro study of blast cell metabolism in acute myeloid leukaemia using the MTT assay.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Size; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Individuality; Leukemia, Myeloid; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 1996 |
Mechanisms of cryoinjury and cryoprotection in split-thickness skin.
Topics: Animals; Cryopreservation; Cryoprotective Agents; Evaluation Studies as Topic; Ice; In Vitro Techniques; Keratinocytes; Kinetics; Oxidation-Reduction; Oxygen Consumption; Skin; Swine; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 1996 |
Radiosensitivity of mesothelioma cell lines.
Topics: Aneuploidy; Cell Cycle; Cell Line; Cell Survival; Coloring Agents; Diploidy; DNA, Neoplasm; Dose-Response Relationship, Radiation; Fetus; Fibroblasts; Flow Cytometry; G1 Phase; HeLa Cells; Humans; Linear Models; Mesothelioma; Pleural Neoplasms; Ploidies; Radiation Tolerance; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
A new in vitro model of specific targeting therapy of cancer: retargeting of PWM-LAK cells with bispecific antibodies greatly enhances cytotoxicity to hepatocellular carcinoma.
Topics: Antibodies, Bispecific; Antibodies, Monoclonal; Antibody Specificity; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Humans; Immunotoxins; Phenotype; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
In vitro biocompatibility of bioresorbable polymers: poly(L, DL-lactide) and poly(L-lactide-co-glycolide).
Topics: 3T3 Cells; Animals; Antimetabolites; Biocompatible Materials; Bromodeoxyuridine; Buffers; Cells, Cultured; Coloring Agents; DNA; Fibroblasts; Fluorescent Dyes; Immunodiffusion; Mice; Mice, Inbred BALB C; Mitochondria; Polyesters; Polyglycolic Acid; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 1996 |
In vitro cytotoxicity and immunomodulating property of Rhaphidophora korthalsii.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Division; Colonic Neoplasms; Coloring Agents; Concanavalin A; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Leukemia P388; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Nasopharyngeal Neoplasms; Plant Extracts; Plant Lectins; Plants, Medicinal; Spleen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Water | 1996 |
An in vitro test system for thyroid hormone action.
Topics: Animals; Biological Assay; Cell Division; Cell Line; Culture Media, Serum-Free; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorescent Dyes; L-Lactate Dehydrogenase; Pituitary Neoplasms; Rats; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Triiodothyronine; Tumor Cells, Cultured | 1996 |
Sulphated compounds attenuate beta-amyloid toxicity by inhibiting its association with cells.
Topics: Amyloid beta-Peptides; Coloring Agents; Congo Red; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Protein Binding; Protein Structure, Secondary; Sulfates; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 1995 |
Dopamine secretion by PC12 cells microencapsulated in a hydroxyethyl methacrylate--methyl methacrylate copolymer.
Topics: Animals; Biocompatible Materials; Calcium; Capsules; Cell Nucleus; Cell Survival; Chromatin; Coloring Agents; Dopamine; Kinetics; Methylmethacrylates; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria; Necrosis; PC12 Cells; Polyhydroxyethyl Methacrylate; Rats; Tetrazolium Salts; Thiazoles; Vacuoles | 1996 |
Neural tissue engineering: from polymer to biohybrid organs.
Topics: Animals; Astrocytes; Biocompatible Materials; Brain Tissue Transplantation; Capsules; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Techniques; Embryo, Mammalian; Immunohistochemistry; Methacrylates; Microscopy, Electron, Scanning; Neurons; Rats; Schwann Cells; Sciatic Nerve; Tetrazolium Salts; Thiazoles | 1996 |
Chromium- and nickel-induced cytotoxicity in normal and transformed human keratinocytes: an investigation of pharmacological approaches to the prevention of Cr(VI)-induced cytotoxicity.
Topics: Ascorbic Acid; Cell Culture Techniques; Cell Death; Cell Line, Transformed; Cell Survival; Chromium; Dose-Response Relationship, Drug; Humans; Keratinocytes; L-Lactate Dehydrogenase; Neutral Red; Nickel; Tetrazolium Salts; Thiazoles | 1996 |
Stimulation of cytokine production via a special standardized mistletoe preparation in an in vitro human skin bioassay.
Topics: Biological Assay; Cell Count; Cytokines; Dinoprostone; Humans; Interleukin-1; Interleukin-6; L-Lactate Dehydrogenase; Limulus Test; Mistletoe; Plant Extracts; Plant Preparations; Plant Proteins; Plants, Medicinal; Reproducibility of Results; Ribosome Inactivating Proteins, Type 2; Skin; Tetrazolium Salts; Thiazoles; Toxins, Biological | 1996 |
Cellular MTT reduction distinguishes the mechanism of action of beta-amyloid from that of tachykinin receptor peptides.
Topics: Amyloid beta-Peptides; Animals; Cell Death; Coloring Agents; Embryo, Mammalian; Humans; Kidney; Neuroblastoma; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Receptors, Tachykinin; Tachykinins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Apoptosis in human monocyte-macrophages exposed to oxidized low density lipoprotein.
Topics: Adenine; Apoptosis; Cell Culture Techniques; DNA Damage; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Lipoproteins, LDL; Macrophages; Microscopy, Electron; Monocytes; Neutral Red; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 1996 |
Detection of clostridium perfringens toxins using cell cultures.
Topics: Animal Testing Alternatives; Animals; Bacterial Toxins; Biological Assay; Cell Line; Clostridium perfringens; Coloring Agents; Dogs; Neutral Red; Tetrazolium Salts; Thiazoles | 1996 |
Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba.
Topics: Acetamides; Acetonitriles; Animals; Antineoplastic Agents; Benzoquinones; Carcinoma, Ehrlich Tumor; Cyclohexenes; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Glutathione; HeLa Cells; Humans; Mice; Porifera; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Detection of interleukin-1 signal transduction inhibitors: action of protein kinase inhibitors.
Topics: Cell Division; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1; Interleukin-6; KB Cells; Leucine; Molecular Weight; Protein Kinase C; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles | 1995 |
Ruthenium Red potently inhibits immune responses both in vitro and in vivo.
Topics: Animals; Antibody Formation; Ca(2+) Mg(2+)-ATPase; Calcium; Cell Membrane; Enzyme-Linked Immunosorbent Assay; Female; Growth Substances; Humans; Immunity, Cellular; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Rats; Ruthenium Red; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1995 |
Assay of anticancer drugs in tissue culture: comparison of a tetrazolium-based assay and a protein binding dye assay in short-term cultures derived from human malignant glioma.
Topics: Antineoplastic Agents; Coloring Agents; Drug Screening Assays, Antitumor; Glioma; Humans; Lomustine; Procarbazine; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1996 |
Cytokine activity assay by means of proliferation measured in plane convex microtiter wells.
Topics: Animals; Calibration; Cell Division; Cell Line; Colorimetry; Cytokines; Interleukin-2; Mice; Microchemistry; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Thiazoles | 1996 |
Evaluation of antiherpetic compounds using a gastric cancer cell line: pronounced activity of BVDU against herpes simplex virus replication.
Topics: Adenocarcinoma; Antiviral Agents; Bromodeoxyuridine; Colorimetry; Coloring Agents; Drug Evaluation, Preclinical; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Virus Replication | 1996 |
Comparison of various methods of assaying the cytotoxic effects of ethanol on human hepatoblastoma cells (HUH-6 line).
Topics: Cell Survival; Coloring Agents; DNA, Neoplasm; Ethanol; Humans; L-Lactate Dehydrogenase; Liver; Spheroids, Cellular; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Application of a combination of neutral red and amido black staining for rapid, reliable cytotoxicity testing of biomaterials.
Topics: Amido Black; Animals; Biocompatible Materials; Cell Count; Cell Division; Cell Survival; Coloring Agents; Evaluation Studies as Topic; L Cells; Materials Testing; Mice; Neutral Red; Prostheses and Implants; Spectrophotometry; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1996 |
Interactions of orthopaedic metals with an immortalized rat osteoblast cell line.
Topics: Alkaline Phosphatase; Aluminum; Animals; Biocompatible Materials; Cell Line; Chromium; Coloring Agents; Materials Testing; Metals; Nickel; Osteoblasts; Prostheses and Implants; Rats; Tetrazolium Salts; Thiazoles; Vanadium | 1996 |
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Colorimetric susceptibility testing for Aspergillus fumigatus: comparison of menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and Alamar blue tests.
Topics: Amphotericin B; Antifungal Agents; Aspergillus fumigatus; Candida albicans; Coloring Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Oxazines; Tetrazolium Salts; Thiazoles; Xanthenes | 1996 |
A rapid, colourimetric assay for cytotoxin activity in Campylobacter jejuni.
Topics: Animals; Campylobacter jejuni; Chlorocebus aethiops; Colorimetry; Cytotoxins; Enterotoxins; HeLa Cells; Humans; Immunoassay; Latex Fixation Tests; Tetrazolium Salts; Thiazoles; Vero Cells | 1996 |
Immunomodulative effects of aflatoxins and selenium on human peripheral blood lymphocytes.
Topics: Adjuvants, Immunologic; Aflatoxin B1; Carcinogens; Colorimetry; Coloring Agents; DNA; Drug Interactions; Humans; Immunosuppressive Agents; Isotope Labeling; Neutral Red; Phytohemagglutinins; Selenium; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1996 |
MTT assay overestimates human airway smooth muscle cell number in culture.
Topics: Bronchi; Cell Count; Cell Division; Cells, Cultured; Coloring Agents; Fluorescent Dyes; Humans; Lung Neoplasms; Mitochondria; Muscle, Smooth; Reproducibility of Results; Rhodamine 123; Rhodamines; Spectrophotometry; Tetrazolium Salts; Thiazoles | 1996 |
Inhibitory effect of BQ-123 on endothelin-1-stimulated mitogen-activated protein kinase and cell growth of rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Peptides, Cyclic; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Thymidine | 1996 |
Toxicity parameters for cytotoxicity testing of dental materials in two different mammalian cell lines.
Topics: Animals; Automation; Biocompatible Materials; Cell Division; Cell Line; Cell Line, Transformed; Cell Survival; Colorimetry; Coloring Agents; Composite Resins; Cytological Techniques; Dental Materials; Fibroblasts; Gingiva; Glass Ionomer Cements; Humans; Materials Testing; Mice; Neutral Red; Proteins; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Zinc Phosphate Cement | 1996 |
Augmentation of epirubicin cytotoxicity by cycloheximide.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Cycloheximide; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Epirubicin; Leukemia P388; Mice; Protein Synthesis Inhibitors; Tetrazolium Salts; Thiazoles | 1996 |
A protein phosphatase 2A inhibition assay for a fast and sensitive assessment of okadaic acid contamination in mussels.
Topics: Animals; Bivalvia; Carcinogens; Coloring Agents; Digestive System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Food Contamination; Lethal Dose 50; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 2; Reproducibility of Results; Shellfish; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 1996 |
Comparison of the toxicities of cisplatin and a new cisplatin-procaine complex to rat renal cortical slices.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Cisplatin; Female; Glutathione; In Vitro Techniques; Kidney Cortex; Kidney Diseases; L-Lactate Dehydrogenase; Organoplatinum Compounds; Procaine; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 1996 |
Characterization of the cell response of cultured macrophages and fibroblasts to particles of short-chain poly[(R)-3-hydroxybutyric acid].
Topics: 3T3 Cells; Animals; Biotransformation; Cell Death; Cell Line; Cell Survival; Collagen; Fibroblasts; Fibronectins; Flow Cytometry; Fluorescent Dyes; Hydroxybutyrates; Macrophage Activation; Macrophages; Mice; Microscopy, Electron; Nitrites; Phagocytosis; Polyesters; Prohibitins; Rats; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1996 |
The induction of cyclooxygenase-2 (COX-2) in intact human amnion tissue by interleukin-4.
Topics: Amnion; Cell Survival; Colorimetry; Coloring Agents; Culture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Evaluation Studies as Topic; Female; Humans; Interleukin-4; Isoenzymes; Membrane Proteins; Obstetric Labor, Premature; Pregnancy; Prostaglandin-Endoperoxide Synthases; Tetrazolium Salts; Thiazoles | 1996 |
Amyloid beta toxicity consists of a Ca(2+)-independent early phase and a Ca(2+)-dependent late phase.
Topics: Amyloid beta-Peptides; Animals; Calcium; Cell Death; Coloring Agents; Embryo, Mammalian; Glutamic Acid; Hippocampus; Kinetics; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors | 1996 |
Increased L-arginine transport in a nitric oxide-producing metastatic colon cancer cell line.
Topics: Adenocarcinoma; Arginine; Biological Transport; Cell Division; Cell Membrane; Colonic Neoplasms; Coloring Agents; Dexamethasone; Glucocorticoids; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphatic Metastasis; Nitric Oxide; Sodium; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Up-Regulation | 1996 |
Effects of energy deprivation induced by fluorocitrate in immortalised rat brain microvessel endothelial cells.
Topics: Actins; Adenosine Triphosphate; Animals; Capillary Permeability; Cell Line, Transformed; Cerebrovascular Circulation; Citrates; Cytoskeleton; Endothelium, Vascular; Energy Metabolism; Glucose; Intracellular Membranes; Lactic Acid; Microcirculation; Rats; Tetrazolium Salts; Thiazoles | 1996 |
Cytotoxicity of macrolide antibiotics in a cultured human liver cell line.
Topics: Anti-Bacterial Agents; Azithromycin; Cell Line; Clarithromycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epithelial Cells; Epithelium; Erythromycin; Humans; Liver; Proteins; Roxithromycin; Tetrazolium Salts; Thiazoles | 1996 |
The effects of nerve growth factor and ganglioside GM1 on the anti-proliferative activity of cocaine in PC12 cells.
Topics: Animals; Cell Division; Cocaine; G(M1) Ganglioside; Nerve Growth Factors; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles | 1996 |
The use of intermediate electron acceptors to enhance MTT bioreduction in a microculture tetrazolium assay for human growth hormone.
Topics: Animals; Electrons; Growth Hormone; Humans; Oxidation-Reduction; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Assessment of antiviral activity, efficacy, and toxicity of prostaglandin A2 in a rabbit model of herpetic keratitis.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cornea; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Prostaglandins A; Rabbits; Stromal Cells; Tetrazolium Salts; Thiazoles; Trigeminal Ganglion; Virus Replication | 1996 |
Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cell Line; Cloning, Molecular; Electroporation; HeLa Cells; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Recombination, Genetic; RNA, Viral; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 1996 |
Suitability of the MTT-based cytotoxicity assay to detect okadaic acid contamination of mussels.
Topics: Animals; Bivalvia; Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; Injections, Intraperitoneal; KB Cells; Lethal Dose 50; Mice; Okadaic Acid; Oxidation-Reduction; Reproducibility of Results; Shellfish Poisoning; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Ginkgo biloba attenuates oxidative stress in macrophages and endothelial cells.
Topics: Animals; Antioxidants; Cell Line; Cell Survival; China; Coloring Agents; Endothelium, Vascular; Fluoresceins; Fluorescence; Free Radical Scavengers; Ginkgo biloba; L-Lactate Dehydrogenase; Lipid Peroxidation; Macrophages; Mice; Oxidative Stress; Peroxides; Plant Extracts; Reactive Oxygen Species; Respiratory Burst; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 1996 |
Alpha 1-antichymotrypsin interaction with A beta (1-42) does not inhibit fibril formation but attenuates the peptide toxicity.
Topics: alpha 1-Antichymotrypsin; Amyloid beta-Peptides; Animals; Cells, Cultured; Coloring Agents; Hippocampus; Humans; Microscopy, Electron; Neurofibrils; Neurotoxins; Peptide Fragments; Rats; Serine Proteinase Inhibitors; Tetrazolium Salts; Thiazoles | 1996 |
Ceramide reproduces late appearance of oxidative stress during TNF-mediated cell death in L929 cells.
Topics: Animals; Cell Death; Cell Survival; Ceramides; Clone Cells; Coloring Agents; Drug Resistance; Free Radical Scavengers; Kinetics; L Cells; Mice; Mutagenesis; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Puromycin; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha | 1996 |
Using MTT viability assay to test the cytotoxicity of antibiotics and steroid to cultured porcine corneal endothelial cells.
Topics: Animals; Anti-Bacterial Agents; Cell Survival; Cells, Cultured; Coloring Agents; Endothelium, Corneal; Swine; Tetrazolium Salts; Thiazoles | 1996 |
Alpha-lipoic acid blocks HIV-1 LTR-dependent expression of hygromycin resistance in THP-1 stable transformants.
Topics: Acetylcysteine; Antioxidants; Cell Line; Drug Resistance; Gene Expression Regulation, Viral; HIV Core Protein p24; HIV Long Terminal Repeat; HIV-1; Humans; Hygromycin B; Macrophages; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Promoter Regions, Genetic; Tetrazolium Salts; Thiazoles; Thioctic Acid; Transfection; Tumor Necrosis Factor-alpha | 1996 |
A colorimetric LDH assay for the titration of infectivity and the evaluation of anti-viral activity against ortho- and paramyxoviruses.
Topics: Antiviral Agents; Colorimetry; Cytopathogenic Effect, Viral; Humans; L-Lactate Dehydrogenase; Melanoma, Experimental; Orthomyxoviridae; Paramyxoviridae; Ribavirin; Ribonucleosides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Viral Plaque Assay | 1995 |
Increased IL-1, IL-6 and TNF alpha secretion and mRNA levels in WEHI-3 cells exposed to cyclopiazonic acid.
Topics: Analysis of Variance; Animals; Base Sequence; Cell Division; Cell Line; Cell Survival; Coloring Agents; Enzyme Inhibitors; Gene Expression Regulation; Indoles; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Mycotoxins; Nucleic Acid Hybridization; Polymerase Chain Reaction; RNA, Messenger; Salmonella typhimurium; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha; Up-Regulation | 1996 |
Modulation of sensitivity to cis-diamminedichloroplatinum (II) by thromboxane A2 receptor antagonists in non-small-cell lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Benzoquinones; Bridged Bicyclo Compounds; Carcinoma, Non-Small-Cell Lung; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Fatty Acids, Monounsaturated; Heptanoic Acids; Humans; Lung Neoplasms; Prostaglandin Antagonists; Receptors, Thromboxane; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Comparative study of classical, colorimetric and immunologic staining methods for the assessment of tumor cell viability.
Topics: Antineoplastic Agents; Apoptosis; Cell Survival; Colonic Neoplasms; Colorimetry; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mitochondria; Spectrophotometry; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trypan Blue | 1996 |
A colorimetric assay to evaluate the cytotoxic activity of the intestinal intraepithelial lymphocytes of chickens.
Topics: Animals; Cell Survival; Chickens; Chlorocebus aethiops; Colorimetry; Coloring Agents; Duodenum; Killer Cells, Natural; Lymphocytes; Tetrazolium Salts; Thiazoles; Vero Cells | 1996 |
The effect of sodium hyaluronate on the growth of rabbit corneal epithelial cells in vitro.
Topics: Animals; Cell Division; Cells, Cultured; Coloring Agents; Cornea; DNA; DNA Replication; Dose-Response Relationship, Drug; Epithelium; Hyaluronan Receptors; Hyaluronic Acid; Rabbits; Tetrazolium Salts; Thiazoles; Thymidine | 1996 |
Development of a novel in vitro chemosensitivity assay: telomerase as a possible marker of tumor cell survival.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Carmustine; Cell Count; Cell Survival; Coloring Agents; Humans; Jurkat Cells; Telomerase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haemin.
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Synergism; Hemin; Neurites; Neurons; Rats; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 1997 |
Syringin 4-O-beta-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii.
Topics: Animals; Cell Survival; Coloring Agents; Enzyme Inhibitors; Hydrolysis; Immunosuppressive Agents; Lactose; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Nitric Oxide Synthase; Plant Epidermis; Plants, Medicinal; Sesquiterpenes; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 1996 |
Development of an in vitro method for skin corrosion testing.
Topics: Animal Testing Alternatives; Cell Survival; Coloring Agents; Culture Techniques; Dermatitis, Contact; Humans; Irritants; Necrosis; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 1996 |
Comparison of the toxicity of allyl alcohol, coumarin and menadione in precision-cut rat, guinea-pig, cynomolgus monkey and human liver slices.
Topics: 1-Propanol; Animals; Coloring Agents; Coumarins; Guinea Pigs; Humans; Liver; Macaca fascicularis; Male; Potassium; Propanols; Protein Biosynthesis; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests; Vitamin K | 1996 |
Differential expression of apoptosis receptors on diffuse and intestinal type stomach carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Apoptosis; Blotting, Western; Coloring Agents; Electrophoresis; fas Receptor; Female; Frozen Sections; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Male; Middle Aged; Receptors, Cell Surface; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 1997 |
Prolactin-like biological activity in the pituitary glands of the marsupial Monodelphis domestica and of the amphibian Rana pipiens detected by a colorimetric Nb2 lymphoma cell proliferation assay.
Topics: Animals; Biological Assay; Cell Division; Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Female; Lymphoma; Opossums; Pituitary Gland; Prolactin; Rana pipiens; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Thyrotropin-Releasing Hormone | 1997 |
Interaction between polyalkylcyanoacrylate nanoparticles and peritoneal macrophages: MTT metabolism, NBT reduction, and NO production.
Topics: Animals; Cell Survival; Cells, Cultured; Cyanoacrylates; Drug Carriers; Female; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; Nitroblue Tetrazolium; Polymers; Respiratory Burst; Tetrazolium Salts; Thiazoles; Thioglycolates | 1997 |
Quantitative structure-activity relationship and cytotoxicity.
Topics: Benzyl Alcohols; Cell Survival; Cells, Cultured; Fibroblasts; Humans; Hydrogen-Ion Concentration; Skin; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Toxicity Tests | 1995 |
Measurement of proinflammatory mediator production by cultured keratinocytes.
Topics: Adult; Cell Line, Transformed; Cells, Cultured; Culture Techniques; Female; Humans; Interleukin-1; Interleukin-6; Keratinocytes; Middle Aged; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 1995 |
Apoptotic retinal cell death induced by antirecoverin autoantibodies of cancer-associated retinopathy.
Topics: Animals; Antigens, Neoplasm; Apoptosis; Autoantibodies; Calcium-Binding Proteins; Cell Death; Cell Survival; Coloring Agents; Complement System Proteins; Cytotoxicity, Immunologic; DNA; DNA Fragmentation; Dose-Response Relationship, Immunologic; Eye Proteins; Hippocalcin; Humans; Immunoenzyme Techniques; Lipoproteins; Nerve Tissue Proteins; Rabbits; Rats; Receptors, Fc; Recoverin; Retina; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Antitumor activity of paclitaxel against human breast carcinoma xenografts serially transplanted into nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Mitomycin; Neoplasm Transplantation; Paclitaxel; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1997 |
Comparative evaluation of the antiproliferative effect of cyclosporin A and gamma-interferon on normal and HPV-transformed keratinocytes by cell counting, MTT assay and tritiated thymidine incorporation.
Topics: Adult; Cell Count; Cell Division; Cell Line, Transformed; Cell Survival; Cells, Cultured; Coloring Agents; Cyclosporine; Growth Inhibitors; Humans; Interferon-gamma; Keratinocytes; Papillomaviridae; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1997 |
Association of nitric oxide production by kidney proximal tubular cells in response to lipopolysaccharide and cytokines with cellular damage.
Topics: Animals; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Cytokines; Immunohistochemistry; Interleukin-1; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipopolysaccharides; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Sodium; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1997 |
N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes.
Topics: Animals; Antifungal Agents; Cell Membrane; Cells, Cultured; Coloring Agents; Female; Ketoconazole; L-Lactate Dehydrogenase; Liver; Male; Mitochondria; Oxidation-Reduction; Oxygenases; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1997 |
Quantification of tumour cell-endothelial cell attachment by 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine (DiI).
Topics: Bisbenzimidazole; Carbocyanines; Cell Adhesion; Cell Communication; Endothelium, Vascular; Fluorescent Dyes; Humans; Neoplasms; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 1997 |
Effects of eosinophil granule proteins on human corneal epithelial cell viability and morphology.
Topics: Blood Proteins; Cell Survival; Cells, Cultured; Coloring Agents; Cornea; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophil-Derived Neurotoxin; Epithelial Cells; Epithelium; Humans; Inflammation Mediators; Neurotoxins; Peroxidases; Ribonucleases; Tetrazolium Salts; Thiazoles | 1997 |
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Chromatography, High Pressure Liquid; Computer Simulation; Drug Screening Assays, Antitumor; Lactones; Mice; Models, Structural; Molecular Conformation; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Effect of CPT-11 in combination with other anticancer agents in lung cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Interactions; Drug Screening Assays, Antitumor; Humans; Irinotecan; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
In vitro cytotoxicity and DNA damage production in Chinese hamster ovary cells and topoisomerase II inhibition by 2-[2'-(dimethylamino)ethyl]-1, 2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones with substitutions at the 6 and 7 positions (azonafides).
Topics: Animals; Antineoplastic Agents; Cell Survival; Cell-Free System; CHO Cells; Cricetinae; Dimethylamines; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Isoquinolines; Microscopy, Confocal; Neoplasm Proteins; Plasmids; Tetrazolium Salts; Thiazoles; Topoisomerase II Inhibitors | 1997 |
Granulocyte macrophage colony stimulating factor pretreatment induces an increase of rat Kupffer cells with enhanced cytotoxicity in vitro and prevention of tumor outgrowth in vivo.
Topics: Animals; Carcinoma; Cell Death; Drug Screening Assays, Antitumor; Granulocyte Colony-Stimulating Factor; Immunohistochemistry; Kupffer Cells; Liver Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 1997 |
Blocking the endogenous increase in HSP 72 increases susceptibility to hypoxia and reoxygenation in isolated adult feline cardiocytes.
Topics: Animals; Antisense Elements (Genetics); Base Sequence; Cats; Cell Separation; Cell Survival; Disease Susceptibility; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Hypoxia; L-Lactate Dehydrogenase; Molecular Sequence Data; Myocardium; Oxygen; Tetrazolium Salts; Thiazoles | 1997 |
Simple and reliable methods to assess hepatocyte viability in bioartificial liver support system matrices.
Topics: Animals; Biocompatible Materials; Cell Separation; Cell Survival; Cell Transplantation; Cells, Cultured; Dextrans; Formazans; Liver; Liver, Artificial; Microspheres; Mitochondria, Liver; Rats; Software; Swine; Tetrazolium Salts; Thiazoles; Thymidine; Trypan Blue | 1997 |
Use of an enzymatic micromethod to quantify amastigote stage of Leishmania amazonensis in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Leishmania; Parasitology; Pentamidine; Tetrazolium Salts; Thiazoles; Trypanocidal Agents | 1997 |
Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.
Topics: Antineoplastic Agents, Phytogenic; Artemisinins; Cell Cycle; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Biologically active acylglycerides from the berries of saw-palmetto (Serenoa repens).
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Glycerides; Humans; Laurates; Magnetic Resonance Spectroscopy; Monoglycerides; Myristic Acids; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Cell line specific radiosensitizing effect of zalcitabine (2',3'-dideoxycytidine).
Topics: Breast Neoplasms; Cell Cycle; Colonic Neoplasms; Flow Cytometry; Humans; Radiation-Sensitizing Agents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Zalcitabine | 1997 |
Proliferation and differentiation of cultured human keratinocytes is modulated by 1,25(OH)2D3 and synthetic vitamin D3 analogues in a cell density-, calcium- and serum-dependent manner.
Topics: Antibodies, Monoclonal; Calcitriol; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Charcoal; Culture Media, Serum-Free; Enzyme-Linked Immunosorbent Assay; Humans; Keratinocytes; Tetrazolium Salts; Thiazoles | 1997 |
Indomethacin enhances the cytotoxicity of VCR and ADR in human pulmonary adenocarcinoma cells.
Topics: Adenocarcinoma; Adjuvants, Pharmaceutic; Coloring Agents; Doxorubicin; Drug Combinations; Drug Screening Assays, Antitumor; Etoposide; Humans; Indomethacin; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1997 |
Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells.
Topics: Actins; Animals; Antimetabolites; Blood Vessels; Capillary Permeability; Cell Line, Transformed; Cytoskeleton; Endothelium, Vascular; Glucose; Lactic Acid; Microcirculation; Oxidation-Reduction; Pyrithiamine; Rats; Tetrazolium Salts; Thiamine Deficiency; Thiazoles | 1997 |
Apoptosis and resistance to daunorubicin in human leukemic cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Daunorubicin; Drug Resistance; Humans; Leukemia; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Implication of CYP 3A in the toxicity of cyclosporin G (CsG), cyclosporin A (CsA) and FK506 on rat hepatocytes in primary culture.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Calcium; Cell Survival; Cells, Cultured; Coloring Agents; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Flow Cytometry; Immunosuppressive Agents; Intracellular Fluid; Liver; Male; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Tacrolimus; Tetrazolium Salts; Thiazoles | 1997 |
Prednicarbate biotransformation in human foreskin keratinocytes and fibroblasts.
Topics: Administration, Topical; Anti-Inflammatory Agents; Biotransformation; Cell Survival; Chromatography, High Pressure Liquid; Fibroblasts; Glucocorticoids; Humans; Keratinocytes; Male; Prednisolone; Skin; Tetrazolium Salts; Thiazoles | 1997 |
Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Curcumin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Ornithine Decarboxylase; Tetrazolium Salts; Thiazoles | 1997 |
Synthesis and cytotoxic activity of indolyl thiazoles.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Drug Screening Assays, Antitumor; Humans; Indoles; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Rapid cytocidal and cytostatic chemosensitivity test by measuring total amount of mRNA.
Topics: Drug Screening Assays, Antitumor; Humans; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Cell Survival; Circular Dichroism; Microscopy, Electron; Molecular Sequence Data; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles; Ultracentrifugation | 1997 |
Effect of beta-cell toxins on genetically engineered insulin-secreting cells.
Topics: Alloxan; Animals; Cell Adhesion; Cell Line; Cell Survival; Coloring Agents; Fluorescent Dyes; Genetic Engineering; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Mice; Mice, Inbred NOD; Pentamidine; Streptozocin; Tetrazolium Salts; Thiazoles; Toxins, Biological; Transfection | 1997 |
Survival of human epidermal keratinocytes after short-duration high temperature: synthesis of HSP70 and IL-8.
Topics: Cell Survival; Cells, Cultured; Coloring Agents; Epidermal Cells; Epidermis; Female; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Interleukin-8; Keratinocytes; Kinetics; Mammaplasty; Tetrazolium Salts; Thiazoles; Time Factors | 1997 |
Estimation of the chemosensitizing activity of modulators of multi-drug resistance via combined simultaneous analysis of sigmoidal dose-response curves.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Propafenone; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.
Topics: Animals; Brain; Cell Division; Cell Membrane Permeability; Coloring Agents; Endocytosis; Endosomes; Ethylmaleimide; Exocytosis; Lysosomes; Membrane Lipids; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Silicone rubber-hydrogel composites as polymeric biomaterials. IX. Composites containing powdery polyacrylamide hydrogel.
Topics: 3T3 Cells; Acrylic Resins; Animals; Biocompatible Materials; Cell Adhesion; Composite Resins; Humans; Keratinocytes; Materials Testing; Mice; Polymers; Powders; Prostheses and Implants; Rats; Rats, Wistar; Silicones; Spectrophotometry, Ultraviolet; Tensile Strength; Tetrazolium Salts; Thiazoles; Water | 1997 |
Time- and concentration-dependence of the growth-promoting activity of insulin and histamine in Tetrahymena. Application of the MTT-method for the determination of cell proliferation in a protozoan model.
Topics: Animals; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Histamine; Hypoglycemic Agents; Insulin; Tetrahymena pyriformis; Tetrazolium Salts; Thiazoles; Time Factors | 1997 |
Modulation of energy status and cytotoxicity induced by FK506 and cyclosporin A in a renal epithelial cell line.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cyclosporine; Energy Metabolism; Immunosuppressive Agents; Kidney; LLC-PK1 Cells; Nucleotides; Swine; Tacrolimus; Tetrazolium Salts; Thiazoles; Time Factors | 1997 |
Tetrazolium-dye-linked alcohol dehydrogenase of the methylotrophic actinomycete Amycolatopsis methanolica is a three-component complex.
Topics: Actinobacteria; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Flavins; Tetrazolium Salts; Thiazoles | 1997 |
Toxicity assessment of 16 inorganic environmental pollutants by six bioassays.
Topics: Animals; Biological Assay; Cell Line; Coloring Agents; Environmental Pollutants; Fibroblasts; Metals, Heavy; Mice; Neutral Red; RNA; Sensitivity and Specificity; Tetrahymena pyriformis; Tetrazolium Salts; Thiazoles; Trace Elements | 1997 |
Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; DNA, Neoplasm; Drug Resistance; Electron Transport Complex II; Electron Transport Complex III; Glutathione; Humans; Mitochondria; Multienzyme Complexes; NAD(P)H Dehydrogenase (Quinone); Oxidoreductases; Platinum; Serine Proteinase Inhibitors; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Optimization of test conditions for development of MTT as in vitro screen.
Topics: Animals; Cold Temperature; Colorimetry; Coloring Agents; Dipetalonema; Female; Filariasis; Hot Temperature; Male; Muridae; Tetrazolium Salts; Thiazoles | 1997 |
Induction of intracellular ceramide by interleukin-1 beta in oligodendrocytes.
Topics: Animals; Apoptosis; Cell Nucleus; Cell Survival; Cells, Cultured; Ceramides; Chromatin; Coloring Agents; Dose-Response Relationship, Drug; Interleukin-1; Intracellular Fluid; Methods; Oligodendroglia; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sphingomyelins; Staining and Labeling; Tetrazolium Salts; Thiazoles; Time Factors | 1997 |
Cycling assay for nicotinamide adenine dinucleotides: NaCl precipitation and ethanol solubilization of the reduced tetrazolium.
Topics: Brassica; Chemical Precipitation; Coloring Agents; Ethanol; Formazans; Indicators and Reagents; NAD; Oxidation-Reduction; Sodium Chloride; Solanum lycopersicum; Solubility; Spectrophotometry, Atomic; Tetrazolium Salts; Thiazoles | 1997 |
Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Cell Survival; Cells, Cultured; Chromium; Endothelium, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidants; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tyrosine | 1997 |
The invasion-MTT assay as a predictor of liver metastasis using human gastrointestinal carcinomas transplanted in nude mice.
Topics: Animals; Collagen; Coloring Agents; Culture Media, Conditioned; Diffusion Chambers, Culture; Drug Combinations; Extracellular Matrix; Gastrointestinal Neoplasms; Humans; Laminin; Liver Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Predictive Value of Tests; Proteoglycans; Tetrazolium Salts; Thiazoles | 1997 |
Comparison of the PK(15)- and WEHI 164 (clone 13)-based bioassays for detection of porcine tumor necrosis factor.
Topics: Animals; Antibodies; Bacterial Toxins; Biological Assay; Cell Line; Dose-Response Relationship, Drug; Endotoxins; Fibroblasts; Humans; Immunoassay; Kidney; Mice; Recombinant Proteins; Sensitivity and Specificity; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 1997 |
Inhibition of etoposide-induced apoptotic events by azide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azides; Coumarins; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Jurkat Cells; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 1997 |
Comparison of a photometric method with standardized methods of antifungal susceptibility testing of yeasts.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidiasis; Coloring Agents; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Humans; Microbial Sensitivity Tests; Spectrophotometry; Tetrazolium Salts; Thiazoles | 1997 |
Congo red reverses amyloid beta protein-induced cellular stress in astrocytes.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cells, Cultured; Congo Red; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Wistar; Stress, Physiological; Tetrazolium Salts; Thiazoles; Time Factors | 1997 |
Neurotoxin domoic acid produces cytotoxicity via kainate- and AMPA-sensitive receptors in cultured cortical neurones.
Topics: Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; Frontal Lobe; Kainic Acid; Marine Toxins; Mice; Neocortex; Neurons; Neurotoxins; Receptors, AMPA; Receptors, Kainic Acid; Tetrazolium Salts; Thiazoles | 1997 |
Cytotoxic amyloid peptides inhibit cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction by enhancing MTT formazan exocytosis.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Cell Membrane; Cytotoxins; Exocytosis; Formazans; Humans; Islet Amyloid Polypeptide; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1997 |
Apoptosis in cultured human colon cancer cells induced by combined treatments with 5-fluorouracil, tumor necrosis factor-alpha and interferon-alpha.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azure Stains; Cell Survival; Colonic Neoplasms; Coloring Agents; DNA Nucleotidylexotransferase; Fluorouracil; Humans; Interferon-alpha; Methyl Green; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
MTT-hybrid assay incorporates the advantages of both clonogenic and MTT assay radiosensitivity testing for fresh tumor samples.
Topics: Animals; Cell Count; Clone Cells; Histiocytoma, Benign Fibrous; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Optics and Photonics; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1997 |
[Improved MTT colorimetric assay for NKC activity].
Topics: Adult; Colorimetry; Coloring Agents; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia; Tetrazolium Salts; Thiazoles | 1996 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Liposome uptake by human retinal pigment epithelial cells in culture.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arylsulfonates; Cell Survival; Cells, Cultured; Coloring Agents; Fibroblasts; Fluorescent Dyes; Humans; Liposomes; Macrophages; Microscopy, Fluorescence; Middle Aged; Orotic Acid; Phagocytosis; Phospholipids; Pigment Epithelium of Eye; Rabbits; Tetrazolium Salts; Thiazoles | 1997 |
Assessment of cornea viability by confocal laser scanning microscopy and MTT assay.
Topics: Animals; Biological Assay; Cell Survival; Chondroitin Sulfates; Coloring Agents; Complex Mixtures; Cornea; Corneal Transplantation; Culture Media, Serum-Free; Dextrans; Ethidium; Female; Fluoresceins; Fluorescent Dyes; Gentamicins; Intercalating Agents; Male; Microscopy, Confocal; Microscopy, Fluorescence; Rabbits; Tetrazolium Salts; Thiazoles; Tissue Preservation | 1997 |
Synthesis and structure-activity relationships of novel 2',2'-difluoro analogues of docetaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coloring Agents; Crystallography, X-Ray; Docetaxel; Humans; Mass Spectrometry; Mice; Microtubules; Paclitaxel; Structure-Activity Relationship; Swine; Taxoids; Tetrazolium Salts; Thiazoles; Tubulin; Tumor Cells, Cultured | 1997 |
Assay for toxic chemicals using bacteria.
Topics: Bacteria; Coloring Agents; Culture Media; Minerals; Oxidation-Reduction; Platelet Aggregation Inhibitors; Rhizobium; Tetrazolium Salts; Thiazoles; Toxicity Tests; Triazoles | 1997 |
Screening of hepatoprotective plant components using a HepG2 cell cytotoxicity assay.
Topics: Bromobenzenes; Catechin; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Humans; Liver; Plant Extracts; Silymarin; Tetrazolium Salts; Thiazoles | 1997 |
Tumoricidal potential of human macrophages grown in vitro from blood monocytes.
Topics: Adoptive Transfer; Antineoplastic Agents; Cell Count; Cell Separation; Cell Survival; Chromium Radioisotopes; Coloring Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Macrophages; Monocytes; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Differential chemosensitivity in oncogene-transformed cells.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Division; Cell Line; Cell Transformation, Neoplastic; Coloring Agents; Drug Resistance, Neoplasm; Intercalating Agents; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Oncogenes; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Post-exposure processes in Temoporfin-photosensitized cells in vitro: reliance on energy metabolism.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Energy Metabolism; L-Lactate Dehydrogenase; Lipid Peroxidation; Mesoporphyrins; Mice; Photosensitizing Agents; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1997 |
Potentiation of pirarubicin activity in multidrug resistant cells by rifampicin.
Topics: Animals; Antibiotics, Antineoplastic; Antibiotics, Antitubercular; Apoptosis; Cell Cycle; Doxorubicin; Drug Resistance, Multiple; Drug Synergism; Gene Expression Regulation, Neoplastic; Genes, MDR; Leukemia P388; Mice; Rifampin; Tetrazolium Salts; Thiazoles | 1997 |
Identification and characterization of in vitro metabolites of 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H-dibenz [de,h]isoquinoline-1,3-dione (Azonafide).
Topics: Animals; Antineoplastic Agents; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cytosol; DNA Topoisomerases, Type II; DNA, Superhelical; Inactivation, Metabolic; Intercalating Agents; Isoquinolines; Liver; Mass Spectrometry; Molecular Structure; Naphthalimides; Rats; Tetrazolium Salts; Thiazoles | 1998 |
Tetrazolium (MTT) assay for cellular viability and activity.
Topics: Cell Count; Cell Survival; Cells, Cultured; Formazans; Mitochondria; Oxidation-Reduction; Polyamines; Tetrazolium Salts; Thiazoles; Toxicity Tests | 1998 |
Suppression of apoptosis by overexpression of Bcl-2 or Bcl-xL promotes survival and mutagenesis after oxidative damage.
Topics: Apoptosis; bcl-X Protein; Cell Line; Cell Survival; Clone Cells; Gene Expression Regulation; Humans; Hydrogen Peroxide; Lymphocytes; Male; Mutagenesis; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 1997 |
Immunological aspects of the common food colorants, amaranth and tartrazine.
Topics: Adult; Amaranth Dye; Cell Division; Cell Survival; Cells, Cultured; Cytotoxicity, Immunologic; DNA; Food Coloring Agents; Humans; Killer Cells, Natural; Lymphocyte Depletion; Neutral Red; Phytohemagglutinins; T-Lymphocytes; Tartrazine; Tetrazolium Salts; Thiazoles; Thymidine | 1998 |
Toxicity of cholesterol oxides on cultured neuroretinal cells.
Topics: Animals; Animals, Newborn; beta-Cyclodextrins; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Cyclodextrins; Dose-Response Relationship, Drug; Hydroxycholesterols; Immunoenzyme Techniques; Neuroglia; Neurons; Rats; Rats, Sprague-Dawley; Retina; Tetrazolium Salts; Thiazoles; Vitamin E | 1998 |
Effects of growth factors on the proliferation of human keratinocytes and fibroblasts in vitro.
Topics: Cell Cycle; Cell Division; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Growth Substances; Humans; Interleukin-1; Keratinocytes; Skin; Tetrazolium Salts; Thiazoles; Thymidine | 1998 |
Metabolic inhibition increases glutamate susceptibility on a PC12 cell line.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Benzoquinones; Cell Hypoxia; Disease Susceptibility; Energy Metabolism; Glutamic Acid; Hypoglycemia; Ischemia; Mitochondria; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles; Ubiquinone; Vitamin E | 1998 |
The therapeutic effect of C1-inhibitor on gut-derived bacterial translocation after thermal injury.
Topics: Animals; Bacterial Translocation; Body Weight; Burns; Complement C1 Inactivator Proteins; Complement Membrane Attack Complex; Complement System Proteins; Digestive System; Edema; Feces; Glycoproteins; Hemodynamics; Kidney; Liver; Lung; Lymph Nodes; Male; Skin; Swine; Tetrazolium Salts; Thiazoles | 1998 |
Amyloid beta-peptide-induced inhibition of MTT reduction in PC12h and C1300 neuroblastoma cells: effect of nitroprusside.
Topics: Amyloid beta-Peptides; Animals; L-Lactate Dehydrogenase; Mice; Neuroblastoma; Nitric Oxide; Nitroprusside; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Sodium Glutamate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Enhanced proliferation of fibroblasts and endothelial cells treated with an extract of the leaves of Chromolaena odorata (Eupolin), an herbal remedy for treating wounds.
Topics: Anti-Infective Agents; Anticoagulants; Burns; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Culture Media; Dermatologic Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibroblasts; Humans; Medicine, Traditional; Multivariate Analysis; Ointments; Plant Extracts; Plant Leaves; Plants, Medicinal; Skin; Soft Tissue Injuries; Tetrazolium Salts; Thiazoles; Time Factors; Vietnam; Wound Healing | 1998 |
The effect of organ preservation solutions on kidney tubular and endothelial cells.
Topics: Cells, Cultured; Coloring Agents; Endothelium, Vascular; Humans; Kidney Tubules; Organ Preservation Solutions; Tetrazolium Salts; Thiazoles | 1998 |
Influence of silicone (PDMS) surface texture on human skin fibroblast proliferation as determined by cell cycle analysis.
Topics: Biocompatible Materials; Cell Cycle; Cell Division; Cell Line; Fibroblasts; Humans; Microscopy, Electron, Scanning; Prostheses and Implants; Silicones; Skin; Surface Properties; Tetrazolium Salts; Thiazoles | 1998 |
Development of an in vitro bioassay system for human thrombopoietin by constructing a recombinant murine cell line expressing human thrombopoietin receptor.
Topics: Animals; Cell Division; Cloning, Molecular; Coloring Agents; Growth Substances; Humans; Mice; Neoplasm Proteins; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Thrombopoietin; Transformation, Genetic; Tumor Cells, Cultured | 1997 |
Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Colonic Neoplasms; Dactinomycin; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, ras; Insulin-Like Growth Factor I; Lovastatin; Mice; Mitochondria; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Chemotherapy in experimental brain tumor, part 1: in vitro colorimetric MTT assay.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Glioma; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Chemotherapy in experimental brain tumor, part 2: pretreatment with leukotriene C4 prolongs survival.
Topics: Animals; Brain Neoplasms; Cell Survival; Cisplatin; Colorimetry; Female; Glioma; Leukotriene C4; Male; Methotrexate; Premedication; Rats; Rats, Sprague-Dawley; Survival Analysis; Tetrazolium Salts; Thiazoles | 1998 |
Diisopropylfluorophosphate (DFP) inhibits ricin-induced apoptosis of MDCK cells.
Topics: ADP Ribose Transferases; Animals; Apoptosis; Bacterial Toxins; Cell Line; Coloring Agents; Diphtheria Toxin; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Exotoxins; Isoflurophate; Kidney; Lectins; Plant Lectins; Protein Synthesis Inhibitors; Pseudomonas aeruginosa Exotoxin A; Ribosome Inactivating Proteins, Type 2; Ricin; Serine Proteinase Inhibitors; Tetrazolium Salts; Thiazoles; Tosyllysine Chloromethyl Ketone; Virulence Factors | 1998 |
Generation and characterization of a mutant of influenza A virus selected with the neuraminidase inhibitor BCX-140.
Topics: Animals; Benzoates; Cell Line; Coloring Agents; Dogs; Drug Resistance, Microbial; Enzyme Inhibitors; Erythrocytes; Hemagglutinins; Humans; Influenza A virus; Mutation; Neuraminidase; Phenotype; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication | 1998 |
Synthesis of new pyrrolo[1,2-d][1,2,4]triazines and thiazolo[3,4-d][1,2,4]triazines as immunostimulating agents.
Topics: Adjuvants, Immunologic; Humans; Hydantoins; Luminescent Measurements; Lymphocyte Activation; Lymphocytes; Pyrimidines; Stimulation, Chemical; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triazines | 1998 |
Use of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide for rapid detection of rifampin-resistant Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Colony Count, Microbial; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Mycobacterium bovis; Mycobacterium tuberculosis; Rifampin; Tetrazolium Salts; Thiazoles; Tuberculosis, Multidrug-Resistant | 1998 |
Tumor necrosis factor-alpha confers resistance to hypoxic injury in the adult mammalian cardiac myocyte.
Topics: Analysis of Variance; Animals; Calcium; Calcium Radioisotopes; Cats; Cell Hypoxia; Cellular Senescence; Heart; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; L-Lactate Dehydrogenase; Mutation; Myocardium; Stimulation, Chemical; Stress, Physiological; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1998 |
A tetrazolium-based colorimetric assay for titration of neutralizing antibodies against vaccinia virus.
Topics: Antibodies, Viral; Cytopathogenic Effect, Viral; Humans; Neutralization Tests; Spectrophotometry; Tetrazolium Salts; Thiazoles; Vaccination; Vaccinia; Vaccinia virus; Viral Plaque Assay | 1998 |
Cytotoxicity of xenobiotics and expression of glutathione-S-transferases in immortalised rat hepatocyte cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Immunoblotting; Isoenzymes; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xenobiotics | 1998 |
Release of interleukin-2 induced by a major antigenic outer membrane protein of Shigella dysenteriae type 1 in natural infection.
Topics: Antibodies, Monoclonal; Antigens, Bacterial; Antigens, Surface; Bacterial Outer Membrane Proteins; Cell Line; Coloring Agents; Dysentery, Bacillary; Electrophoresis, Polyacrylamide Gel; Humans; Immunoenzyme Techniques; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Shigella dysenteriae; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Thiazoles | 1997 |
Cytotoxic action of lindane in neocortical GABAergic neurons is primarily mediated by interaction with flunitrazepam-sensitive GABA(A) receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Insecticides; Mice; Mitochondria; Neocortex; Neurons; Receptors, GABA-A; Tetrazolium Salts; Thiazoles; Time Factors | 1998 |
Cytotoxic action of lindane in cerebellar granule neurons is mediated by interaction with inducible GABA(B) receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cells, Cultured; Cerebellum; Coloring Agents; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hexachlorocyclohexane; Insecticides; Isoxazoles; Mice; Mitochondria; Neurons; Synaptic Transmission; Tetrazolium Salts; Thiazoles | 1998 |
A microtiter plate assay for superoxide using MTT reduction method.
Topics: Animals; Coloring Agents; In Vitro Techniques; Intestine, Small; Microsomes; Mitochondria; Oxidation-Reduction; Rats; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 1997 |
The in vitro influence of eight hormones and growth factors on the proliferation of eight sarcoma cell lines.
Topics: Cell Division; Colorimetry; Culture Media; Epidermal Growth Factor; Estradiol; Fibrosarcoma; Gastrins; Gonadotropin-Releasing Hormone; Growth Substances; Hormones; Humans; Insulin-Like Growth Factor I; Leiomyosarcoma; Platelet-Derived Growth Factor; Progesterone; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Triiodothyronine; Tumor Cells, Cultured | 1998 |
Inhibitors of interleukin-1 beta-converting enzyme-family proteases (caspases) prevent apoptosis without affecting decreased cellular ability to reduce 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide in cerebellar granule neurons.
Topics: Animals; Apoptosis; Calcium; Caspase 1; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cerebellum; Coloring Agents; Cysteine Proteinase Inhibitors; Cytoplasmic Granules; Energy Metabolism; Enzyme Activation; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1998 |
Identification of anti-invasive but noncytotoxic chemotherapeutic agents using the tetrazolium dye MTT to quantitate viable cells in Matrigel.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Collagen; Drug Combinations; Drug Screening Assays, Antitumor; Female; Humans; Laminin; Male; Neoplasm Invasiveness; Proteoglycans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Influence of vinblastine on DNA parameters and multidrug resistance in renal cell carcinoma in vitro.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Renal Cell; Cell Cycle; Cell Division; DNA, Neoplasm; Drug Resistance, Multiple; Flow Cytometry; Humans; In Vitro Techniques; Kidney Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vinblastine | 1998 |
Modulation of resistance to ara-C by bryostatin in fresh blast cells from patients with AML.
Topics: Acute Disease; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Bryostatins; Cell Death; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia, Myeloid; Leukocytes, Mononuclear; Macrolides; Tetrazolium Salts; Thiazoles | 1998 |
The clinical relevance of chemosensitivity testing in ovarian cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Drug Resistance, Neoplasm; Female; Humans; Ovarian Neoplasms; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Cinnamic acid inhibits proliferation and modulates brush border membrane enzyme activities in Caco-2 cells.
Topics: Adenylyl Cyclases; Antineoplastic Agents; Caco-2 Cells; Cell Adhesion; Cell Division; Cinnamates; Cyclic AMP; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Microvilli; Tetrazolium Salts; Thiazoles | 1998 |
Cytotoxicity induced by Erythrina variegata serine proteinase inhibitors in tumor hematopoietic stem cell lines.
Topics: Cell Survival; Erythrina; Hematopoietic Stem Cells; Humans; Jurkat Cells; Plants, Medicinal; Serine Proteinase Inhibitors; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Behaviour of human osteoblasts cultured on bioactive glass coatings.
Topics: Alloys; Biocompatible Materials; Cell Division; Cells, Cultured; Coloring Agents; Glass; Humans; Microscopy, Electron, Scanning; Osteoblasts; Osteocalcin; Polystyrenes; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 1998 |
DOC-2/hDab2, a candidate tumor suppressor gene involved in the development of gestational trophoblastic diseases.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Apoptosis Regulatory Proteins; Blotting, Western; Cell Division; Cell Line; Choriocarcinoma; Coloring Agents; Female; Genes, Tumor Suppressor; Humans; Hydatidiform Mole; Hydatidiform Mole, Invasive; Immunoenzyme Techniques; Molecular Sequence Data; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Proteins; Tetrazolium Salts; Thiazoles; Transfection; Trophoblastic Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Proteins; Uterine Neoplasms | 1998 |
Influence of BDNF and FCS on viability and programmed cell death (PCD) of developing cortical chicken neurons in vitro.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cattle; Cell Count; Cell Survival; Cerebral Cortex; Chickens; Culture Media; DNA; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Neurons; Tetrazolium Salts; Thiazoles | 1998 |
Influence of vitamin E succinate on retinal cell survival.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; alpha-Tocopherol; Animals; Antioxidants; Cell Membrane; Cell Survival; Cells, Cultured; Chick Embryo; Culture Media; Diphenylhexatriene; Dose-Response Relationship, Drug; Fluorescent Dyes; Glutathione Reductase; L-Lactate Dehydrogenase; Retina; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Tocopherols; Vitamin E | 1998 |
Effect of protease class-specific inhibitors on in vitro development of the third- to fourth-stage larvae of Ascaris suum.
Topics: Animals; Anti-Bacterial Agents; Ascaris suum; Coloring Agents; Cysteine Proteinase Inhibitors; Dipeptides; Dose-Response Relationship, Drug; Ketones; Larva; Movement; Pepstatins; Peptides; Protease Inhibitors; Sulfones; Swine; Tetrazolium Salts; Thiazoles; Trypsin Inhibitors | 1998 |
Migration arrest in glioma cells is dependent on the alphav integrin subunit.
Topics: Animals; Blotting, Western; Brain Neoplasms; Cell Line; Cell Movement; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Mice; Mice, Nude; Oligonucleotide Probes; Rats; Receptors, Fibronectin; Reverse Transcriptase Polymerase Chain Reaction; Tenascin; Tetrazolium Salts; Thiazoles | 1998 |
Novel anti-respiratory syncytial(RS) viral compounds: benzodithiin derivatives.
Topics: Antiviral Agents; Cytopathogenic Effect, Viral; HeLa Cells; Heterocyclic Compounds; Humans; Microbial Sensitivity Tests; Respiratory Syncytial Virus, Human; Ribavirin; Tetrazolium Salts; Thiazoles; Time Factors; Virus Replication | 1998 |
In vitro correlation between two colorimetric assays and the pyruvic acid consumption by fibroblasts cultured to determine the sodium laurylsulfate cytotoxicity.
Topics: Cells, Cultured; Colorimetry; Fibroblasts; Humans; NAD; Neutral Red; Pyruvic Acid; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 1998 |
Modification of the MTT method for the study of bilirubin cytotoxicity.
Topics: 2-Propanol; Bilirubin; Cells, Cultured; Coloring Agents; Formazans; Humans; Hydrochloric Acid; Liver; Methods; Tetrazolium Salts; Thiazoles | 1998 |
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
Topics: Adult; Cell Count; Cell Division; Cells, Cultured; Connective Tissue; DNA Replication; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibronectins; Humans; Laminin; Male; Middle Aged; Procollagen; Pyrazines; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 1998 |
Long recovery times improve the detection of cellular resistance in vitro.
Topics: Animals; Antineoplastic Agents; Cisplatin; Coloring Agents; Glioblastoma; Glioma; Humans; Rats; Rhabdomyosarcoma; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1998 |
The inhibitory effect of ursodeoxycholic acid and pentoxifylline on platelet derived growth factor-stimulated proliferation is distinct from an effect by cyclic AMP.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antimetabolites; Bucladesine; Cell Division; Cells, Cultured; Cholagogues and Choleretics; Cyclic AMP; Dideoxyadenosine; Drug Interactions; Enzyme Inhibitors; Fibroblasts; Humans; Pentoxifylline; Platelet-Derived Growth Factor; Stimulation, Chemical; Taurochenodeoxycholic Acid; Tetrazolium Salts; Thiazoles; Ursodeoxycholic Acid | 1998 |
The increase in angiotensin type-2 receptor mRNA level by glutamate stimulation in cultured rat cortical cells.
Topics: Angiotensin II; Animals; Antisense Elements (Genetics); Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Rats; Rats, Wistar; Receptors, Angiotensin; RNA, Messenger; Tetrazolium Salts; Thiazoles | 1998 |
Amyloid beta-peptide (1-40)-mediated oxidative stress in cultured hippocampal neurons. Protein carbonyl formation, CK BB expression, and the level of Cu, Zn, and Mn SOD mRNA.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Creatine Kinase; Hippocampus; Humans; Isoenzymes; Mitochondria; Neurons; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Trypan Blue | 1998 |
Evaluation of in vitro chemosensitivity of antitumor drugs using the MTT assay in fresh human breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Regression Analysis; Tetrazolium Salts; Thiazoles | 1998 |
Optimization and comparison of the MTT assay and the 3H-TdR assay for the detection of IL-2 in helper T cell precursor assays.
Topics: Cell Line; Coloring Agents; Evaluation Studies as Topic; Histocompatibility Testing; Humans; Interleukin-2; Recombinant Proteins; Sensitivity and Specificity; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1998 |
Development of in vitro screening system for assessment of antifilarial activity of compounds.
Topics: Animals; Colorimetry; Coloring Agents; Dipetalonema; Dipetalonema Infections; False Negative Reactions; False Positive Reactions; Female; Filaricides; Male; Microfilariae; Movement; Muridae; Oxidation-Reduction; Predictive Value of Tests; Tetrazolium Salts; Thiazoles | 1998 |
Effect of desipramine on immunological parameters in mice, and their reversal by stress.
Topics: Animals; Antidepressive Agents, Tricyclic; Concanavalin A; Cytokines; Desipramine; Lymphocyte Activation; Lymphokines; Male; Mice; Mice, Inbred C57BL; Mitogens; Organ Size; Spleen; Stress, Physiological; Swimming; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Thymus Gland | 1998 |
Reduction of MTT by glutathione S-transferase.
Topics: Animals; Baculoviridae; Cell Count; Cell Line; Cell Survival; Dinitrochlorobenzene; False Positive Reactions; Formazans; Gene Transfer Techniques; Glutathione; Glutathione Transferase; Insecta; Isoenzymes; Kinetics; Oxidation-Reduction; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles | 1998 |
Biocompatibility testing of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A blocks attached to a central poly(ethylene oxide) B block under in vitro conditions using different L929 mouse fibroblasts cell culture models.
Topics: Animals; Biocompatible Materials; Cell Survival; Cells, Cultured; Fibroblasts; Lactic Acid; Mice; Molecular Weight; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles | 1998 |
Areca nut extract inhibits the growth, attachment, and matrix protein synthesis of cultured human gingival fibroblasts.
Topics: Areca; Cell Adhesion; Cell Division; Cells, Cultured; Collagen; Coloring Agents; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Fibroblasts; Gingiva; Humans; Periodontal Diseases; Plant Extracts; Plants, Medicinal; Prevalence; Proline; Radiopharmaceuticals; Tetrazolium Salts; Thiazoles; Time Factors; Tritium; Vacuoles | 1998 |
Microtiter plate assay for superoxide dismutase using MTT reduction by superoxide.
Topics: Animals; Cattle; Colorimetry; Enzyme Inhibitors; Erythrocytes; Formazans; Kinetics; Pyrogallol; Rats; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 1998 |
The free radical antioxidant vitamin E protects cortical synaptosomal membranes from amyloid beta-peptide(25-35) toxicity but not from hydroxynonenal toxicity: relevance to the free radical hypothesis of Alzheimer's disease.
Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biomarkers; Cells, Cultured; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Neuroprotective Agents; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Synaptosomes; Tetrazolium Salts; Thiazoles; Vitamin E | 1998 |
Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies.
Topics: Administration, Intravesical; Animals; Carcinoma, Transitional Cell; Coloring Agents; Culture Media, Serum-Free; Drug Screening Assays, Antitumor; gamma-Linolenic Acid; Humans; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1998 |
Antiproliferative effect of carotenoids on human colon cancer cells without conversion to retinoic acid.
Topics: Carotenoids; Cell Division; Cell Survival; Colonic Neoplasms; Coloring Agents; Humans; Receptors, Retinoic Acid; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured; Vitamin A | 1998 |
Polyoxoanions are cytotoxic to malignant glioma cells.
Topics: 3T3 Cells; Animals; Anions; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cisplatin; Glioblastoma; Humans; Mice; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1.
Topics: Antioxidants; Cell Survival; Cytochrome P-450 CYP2E1; DNA Fragmentation; Ferric Compounds; Humans; Lipid Peroxidation; Malondialdehyde; Mitochondria; Nitrilotriacetic Acid; Oligopeptides; Oxidative Stress; Oxygen Consumption; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Diisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard.
Topics: Cell Line; Cell Survival; Coloring Agents; Gentian Violet; Glutathione; Humans; Microscopy, Phase-Contrast; Mustard Gas; Neutral Red; Oligopeptides; Tetrazolium Salts; Thiazoles; Time Factors | 1998 |
Antiphospholipid antibodies bind to rat cerebellar granule cells: the role of N-methyl-D-aspartate receptors.
Topics: Animals; Antibodies, Antiphospholipid; Cerebellum; Coloring Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Immunoglobulin G; Mitochondria; Neurons; Neurotoxins; Oxidation-Reduction; Oxidoreductases; Rats; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles | 1998 |
Therapeutic effect of clarithromycin on a transplanted tumor in rats.
Topics: Adenocarcinoma; Animals; Chromium Radioisotopes; Clarithromycin; Collagenases; Coloring Agents; Cytotoxicity, Immunologic; Humans; Interleukin-6; Male; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Neoplasm Transplantation; Rats; Rats, Inbred F344; Spleen; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Intracellular survival of Haemophilus somnus in bovine blood monocytes and alveolar macrophages.
Topics: Animals; Cattle; Cattle Diseases; Colorimetry; Coloring Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Haemophilus; Haemophilus Infections; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages, Alveolar; Monocytes; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1998 |
Ethambutol is toxic to retinal ganglion cells via an excitotoxic pathway.
Topics: Animals; Antitubercular Agents; Calcium; Carbocyanines; Cell Survival; Dose-Response Relationship, Drug; Ethambutol; Ethylenediamines; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Memantine; Membrane Potentials; Mitochondria; N-Methylaspartate; Rats; Retinal Ganglion Cells; Tetrazolium Salts; Thiazoles | 1999 |
The effect of the flavonoids, quercetin, myricetin and epicatechin on the growth and enzyme activities of MCF7 human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Catechin; Cell Division; Flavonoids; Glutathione; Humans; L-Lactate Dehydrogenase; Neoplasm Proteins; Oxidation-Reduction; Quercetin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1998 |
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; HL-60 Cells; Humans; Infant; Infant, Newborn; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; U937 Cells | 1999 |
Subzero nonfreezing storage of isolated rat hepatocytes in University of Wisconsin solution.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cell Separation; Cryopreservation; Glutathione; Hypoxia; Insulin; Lactic Acid; Liver; Male; Microscopy, Electron, Scanning; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Trypan Blue | 1999 |
The effects of various extracellular matrices on renal cell attachment to polymer surfaces during the development of bioartificial renal tubules.
Topics: Animals; Carcinoma, Renal Cell; Cell Adhesion; Cell Line; Collagen; Coloring Agents; Culture Media; Dogs; Epithelial Cells; Extracellular Matrix Proteins; Fibronectins; Humans; Kidney; Kidney Tubules; Kidneys, Artificial; Laminin; Polymers; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 1999 |
Expression of leptin receptor in lung: leptin as a growth factor.
Topics: Animals; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Division; Cells, Cultured; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Mice; Obesity; Proteins; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Buccal mucosa in vitro experiments. I. Confocal imaging of vital staining and MTT assays for the determination of tissue viability.
Topics: Animals; Cell Survival; Coloring Agents; Fluoresceins; Fluorescent Dyes; In Vitro Techniques; Indicators and Reagents; Microscopy, Confocal; Mouth Mucosa; Specimen Handling; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles | 1999 |
Evaluation of the in vitro biocompatibility of various elastomers.
Topics: Biocompatible Materials; Cell Adhesion; Cell Survival; Colorimetry; Elasticity; Flow Cytometry; Humans; KB Cells; Microscopy, Electron, Scanning; Silicone Elastomers; Tetrazolium Salts; Thiazoles | 1999 |
Iron increases manganese superoxide dismutase activity in intestinal epithelial cells.
Topics: Animals; Cell Division; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Intestinal Mucosa; Iron; Lipid Peroxidation; Rats; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 1999 |
Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27.
Topics: Actins; Blotting, Western; Calcium-Binding Proteins; Calponins; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Division; Coloring Agents; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Female; Flow Cytometry; Heparin; Humans; Leiomyoma; Microfilament Proteins; Microtubule-Associated Proteins; Muscle Proteins; Myometrium; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; Tumor Suppressor Proteins; Uterine Neoplasms | 1999 |
Peptide YY inhibits growth of human breast cancer in vitro and in vivo.
Topics: Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Cell Survival; Coloring Agents; Cyclic AMP; Female; Humans; Intracellular Membranes; Mice; Mice, Nude; Peptide YY; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Immunosuppressant deoxyspergualin-induced inhibition of cell proliferation is accompanied with an enhanced reduction of tetrazolium salt.
Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line; Coloring Agents; Female; Guanidines; Hemolytic Plaque Technique; Hybridomas; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Oxidation-Reduction; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Thymidine | 1999 |
Reactive oxygen species-induced apoptosis and necrosis in bovine corneal endothelial cells.
Topics: Acridine Orange; Animals; Apoptosis; Cattle; Cell Survival; Cells, Cultured; Endothelium, Corneal; Ethidium; In Situ Nick-End Labeling; Mitochondria; Necrosis; Photosensitizing Agents; Reactive Oxygen Species; Riboflavin; Rose Bengal; Tetrazolium Salts; Thiazoles | 1999 |
Semiautomated metabolic staining assay for Bacillus cereus emetic toxin.
Topics: Bacillus cereus; Bacterial Toxins; Bacteriological Techniques; Coloring Agents; Emetics; Foodborne Diseases; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vacuoles | 1999 |
Neuroprotective effects of nicergoline in immortalized neurons.
Topics: Animals; Antioxidants; Benzoquinones; Buthionine Sulfoximine; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Maleates; Neurons; Neuroprotective Agents; Nicergoline; Staurosporine; Tetrazolium Salts; Thiazoles; Ubiquinone; Vitamin E | 1999 |
Growth inhibitory effect of L-canavanine against MIA PaCa-2 pancreatic cancer cells is not due to conversion to its toxic metabolite canaline.
Topics: Aminobutyrates; Arginase; Canavanine; Carbon Dioxide; Carbon Radioisotopes; Cell Division; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Pancreatic Neoplasms; Radiometry; Substrate Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Effect of vesnarinone in combination with anti-cancer drugs on lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Coloring Agents; Deoxycytidine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Flow Cytometry; Gemcitabine; Humans; Lung Neoplasms; Pyrazines; Quinolines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Predictive chemotherapy of advanced breast cancer directed by MTT assay in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colorimetry; Coloring Agents; Drug Resistance, Neoplasm; Female; Humans; Middle Aged; Predictive Value of Tests; Prospective Studies; Survival Analysis; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 1999 |
Influence of uranium(VI) speciation for the evaluation of in vitro uranium cytotoxicity on LLC-PK1 cells.
Topics: Animals; Cadmium Chloride; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Epithelial Cells; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; LLC-PK1 Cells; Microscopy, Electron; Neutral Red; Swine; Tetrazolium Salts; Thiazoles; Uranium Compounds | 1999 |
Distinct glycolysis inhibitors determine retinal cell sensitivity to glutamate-mediated injury.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Coloring Agents; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Iodoacetic Acid; Kinetics; Oxidation-Reduction; Retina; Tetrazolium Salts; Thiazoles | 1999 |
Release of methyl methacrylate from heat-cured and autopolymerized resins: cytotoxicity testing related to residual monomer.
Topics: Acrylic Resins; Analysis of Variance; Biocompatible Materials; Cell Survival; Cells, Cultured; Coloring Agents; Denture Bases; Diffusion; Fibroblasts; Humans; Materials Testing; Methylmethacrylate; Polymers; Saliva; Tetrazolium Salts; Thiazoles; Time Factors | 1999 |
Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.
Topics: Adenosine Triphosphatases; Amyloid beta-Peptides; Animals; Anti-Bacterial Agents; Coloring Agents; Enzyme Inhibitors; Macrolides; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles | 1999 |
N-glycosylation of glucose transporter-1 (Glut-1) is associated with increased transporter affinity for glucose in human leukemic cells.
Topics: 3-O-Methylglucose; Cell Division; Deoxyglucose; Glucose; Glucose Transporter Type 1; Glycosylation; HL-60 Cells; Humans; K562 Cells; Leukemia; Monosaccharide Transport Proteins; Tetrazolium Salts; Thiazoles; Tunicamycin; U937 Cells | 1999 |
Effect of ion modification of commonly used orthopedic materials on the attachment of human bone-derived cells.
Topics: Alloys; Biocompatible Materials; Bone and Bones; Calcium Compounds; Cell Adhesion; Cells, Cultured; Chromium Alloys; Colorimetry; Electron Probe Microanalysis; Glass; Humans; Materials Testing; Microscopy, Electron, Scanning; Oxides; Polyethylene Terephthalates; Sodium Hydroxide; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; X-Ray Diffraction | 1999 |
Extracellular matrix inhibits apoptosis and enhances endothelial cell differentiation by a NfkappaB-dependent mechanism.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Differentiation; Cell Line; Cell Nucleus; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytoplasm; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Etoposide; Extracellular Matrix; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Nucleic Acid Synthesis Inhibitors; Oligonucleotides, Antisense; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 1999 |
Modulating activity of indomethacin to vincristine cytotoxicity in various human carcinoma cells.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Survival; Coloring Agents; Female; Fibroblasts; Humans; Indomethacin; Lung Neoplasms; Male; Middle Aged; Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1998 |
Comparison between the clonogenic, MTT, and SRB assays for determining radiosensitivity in a panel of human bladder cancer cell lines and a ureteral cell line.
Topics: Cell Survival; Dose-Response Relationship, Radiation; Humans; Radiation Tolerance; Rhodamines; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay; Ureteral Neoplasms; Urinary Bladder Neoplasms | 1999 |
Miniaturization and application of the MTT assay to evaluate metabolic activity of protozoa in the presence of toxicants.
Topics: Animals; Colorimetry; Copper; Cycloheximide; Octoxynol; Tetrahymena pyriformis; Tetrazolium Salts; Thiazoles; Zinc | 1999 |
Expression of G1 phase regulators in MG-63 osteosarcoma cell line.
Topics: Apoptosis; Bone Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Interleukin-6; Osteosarcoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Accelerated toxicity testing of casting alloys and reduction of intraoral release of elements.
Topics: Animals; Biocompatible Materials; Cell Survival; Cells, Cultured; Chromium Alloys; Coloring Agents; Culture Media; Dental Alloys; Dental Casting Investment; Diffusion; Fibroblasts; Gold Alloys; Materials Testing; Mice; Mice, Inbred BALB C; Mouth; Polytetrafluoroethylene; Serum Albumin, Bovine; Sodium Chloride; Spectrophotometry, Atomic; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors | 1999 |
Both oxidative stress-dependent and independent effects of amyloid beta protein are detected by 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction assay.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Coloring Agents; Exocytosis; Formazans; Neurons; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 1999 |
Laminin inhibits both Abeta40 and Abeta42 fibril formation but does not affect Abeta40 or Abeta42-induced cytotoxicity in PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Coloring Agents; Laminin; PC12 Cells; Peptide Fragments; Rats; Tetrazolium Salts; Thiazoles | 1999 |
Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cells, Cultured; Chloroquine; Coloring Agents; Exocytosis; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1999 |
In vitro cytotoxicity and in vivo biocompatibility of poly(propylene fumarate-co-ethylene glycol) hydrogels.
Topics: Animals; Biocompatible Materials; Cell Count; Cell Survival; Coloring Agents; Exudates and Transudates; Female; Hydrogels; Implants, Experimental; Macrophages; Materials Testing; Microscopy, Electron, Scanning; Oxazines; Polyethylene Glycols; Polypropylenes; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Xanthenes | 1999 |
Focal adhesions and assessment of cytotoxicity.
Topics: Cell Adhesion; Cell Line; Cell Survival; Coloring Agents; Fluorescent Antibody Technique; Gentian Violet; Humans; Ki-67 Antigen; Materials Testing; Muscle, Smooth, Vascular; Nickel; Rosaniline Dyes; Tetrazolium Salts; Thiazoles; Umbilical Veins; Zinc | 1999 |
Synthesis and cytotoxic activity of 1-alkoxy- and 1-amino-2-hydroxy-1,2-dihydroacronycine derivatives.
Topics: Acronine; Animals; Antineoplastic Agents; Humans; Leukemia L1210; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 1999 |
Quantification of metabolic activity in tumour fragments.
Topics: Animals; Colorimetry; Coloring Agents; Cricetinae; Female; Humans; Male; Neoplasm Transplantation; Neoplasms, Experimental; Tetrazolium Salts; Thiazoles | 1998 |
Effects of tobacco products on the attachment and growth of periodontal ligament fibroblasts.
Topics: Analysis of Variance; Cell Adhesion; Cell Count; Cell Division; Cells, Cultured; Coloring Agents; Cotinine; Culture Media; Disease Progression; Fibroblasts; Humans; Nicotiana; Nicotine; Nicotinic Agonists; Periodontal Ligament; Periodontitis; Plants, Toxic; Smoking; Tetrazolium Salts; Thiazoles | 1999 |
Tissue engineering in cardiovascular surgery: MTT, a rapid and reliable quantitative method to assess the optimal human cell seeding on polymeric meshes.
Topics: Biomedical Engineering; Cell Count; Cells, Cultured; Colorimetry; Coloring Agents; Culture Techniques; Fibroblasts; Heart Valves; Humans; Microscopy, Electron, Scanning; Polyglycolic Acid; Surgical Mesh; Tetrazolium Salts; Thiazoles; Time Factors | 1999 |
Scavenging effect of benzophenones on the oxidative stress of skeletal muscle cells.
Topics: Acridines; Animals; Benzophenones; Cell Survival; Drug Evaluation, Preclinical; Free Radical Scavengers; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; Muscle, Skeletal; Oxidative Stress; Rats; Sunscreening Agents; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Vitamin K | 1999 |
Development of a tetrazolium salt assay for rapid determination of viability of BCG vaccines.
Topics: BCG Vaccine; Cell Count; Colony-Forming Units Assay; Coloring Agents; Freeze Drying; Indicators and Reagents; Mycobacterium bovis; Tetrazolium Salts; Thiazoles; Vaccines, Attenuated | 1999 |
Role of sodium ion influx in depolarization-induced neuronal cell death by high KCI or veratridine.
Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Female; Glucose; Ion Transport; Neurons; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Sodium; Tetrazolium Salts; Tetrodotoxin; Thiazoles; Veratridine | 1999 |
In vitro osteoblastic differentiation of human bone marrow cells in the presence of metal ions.
Topics: Alkaline Phosphatase; Alloys; Biocompatible Materials; Bone Marrow Cells; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Chromium; Corrosion; Humans; In Vitro Techniques; Iron; Materials Testing; Metals; Nickel; Osteoblasts; Phosphorus; Prostheses and Implants; Proteins; Stainless Steel; Tetrazolium Salts; Thiazoles | 1999 |
Differences in neurotoxic effects of ochratoxin A, ochracin and ochratoxin-alpha in vitro.
Topics: Animals; Cells, Cultured; Chick Embryo; Coloring Agents; Isocoumarins; Mycotoxins; Neurons; Neurotoxins; Ochratoxins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 1998 |
Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Apoptosis; Calcimycin; Cell Division; Ceramides; Cyclic AMP-Dependent Protein Kinases; DNA Fragmentation; Enzyme Inhibitors; fas Receptor; Female; Flow Cytometry; Humans; Isoquinolines; Ovarian Neoplasms; Protein Kinase C; Signal Transduction; Sphingomyelin Phosphodiesterase; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Imaging and force-distance analysis of human fibroblasts in vitro by atomic force microscopy.
Topics: Cell Division; Cells, Cultured; Coloring Agents; Cytochalasin D; Fibroblasts; Humans; Microscopy, Atomic Force; Tetrazolium Salts; Thiazoles | 1999 |
[Combination effect of hyperthermia and MX2 on cultured glioma cell lines].
Topics: Animals; Antibiotics, Antineoplastic; Carubicin; Cell Survival; Coloring Agents; Combined Modality Therapy; Culture Media; Glioma; Humans; Hyperthermia, Induced; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Influence of gamma-aminobutyric acid on retinal cells excitotoxicity upon glucose deprivation.
Topics: Animals; Bicuculline; Cells, Cultured; Chick Embryo; Coloring Agents; Dose-Response Relationship, Drug; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Glucose; Neurons; Nipecotic Acids; Retina; Tetrazolium Salts; Thiazoles | 1999 |
In vitro elution of antibiotic from antibiotic-impregnated biodegradable calcium alginate wound dressing.
Topics: Alginates; Anti-Bacterial Agents; Bandages; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Coloring Agents; Drug Carriers; Fibroblasts; Freeze Drying; Glucuronic Acid; HeLa Cells; Hexuronic Acids; Humans; In Vitro Techniques; Tetrazolium Salts; Thiazoles; Vancomycin | 1999 |
Cytotoxic activities of hypocretenolides from Leontodon hispidus.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Erythropoiesis; Female; Humans; Male; Plants, Medicinal; Sesquiterpenes; Sesquiterpenes, Guaiane; Stem Cells; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay is a fast and reliable method for colorimetric determination of fungal cell densities.
Topics: Colony Count, Microbial; Colorimetry; Culture Media; Entomophthorales; Evaluation Studies as Topic; Mycology; Tetrazolium Salts; Thiazoles | 1999 |
Immunomodulative effects of some drugs of abuse on human peripheral blood lymphocytes.
Topics: Adult; Cell Line; Cell Survival; Colorimetry; Coloring Agents; Humans; Illicit Drugs; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Neutral Red; Phytohemagglutinins; Tetrazolium Salts; Thiazoles | 1999 |
Ginsenoside RH-2 induces apoptotic cell death in rat C6 glioma via a reactive oxygen- and caspase-dependent but Bcl-X(L)-independent pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspases; DNA Fragmentation; Enzyme Activation; Ginsenosides; Glioma; Immunoblotting; Oxidative Stress; Panax; Plants, Medicinal; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Saponins; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 1999 |
Visualization of the enzyme trimethylamine oxide demethylase in isoelectric focusing gels by an enzyme-specific staining method.
Topics: Aldehyde-Lyases; Coloring Agents; Fish Products; Isoelectric Focusing; Isoelectric Point; Methylphenazonium Methosulfate; Staining and Labeling; Tetrazolium Salts; Thiazoles | 1999 |
The effects of extracellular citric acid acidosis on the viability, cellular adhesion capacity and protein synthesis of cultured human gingival fibroblasts.
Topics: Acidosis; Cell Adhesion; Cell Death; Cell Movement; Cell Survival; Cells, Cultured; Chelating Agents; Chemical Precipitation; Citrates; Citric Acid; Collagen; Coloring Agents; Culture Media; Fibroblasts; Gingiva; Humans; Hydrogen-Ion Concentration; Proline; Protein Biosynthesis; Proteins; Radiopharmaceuticals; Sodium Citrate; Tetrazolium Salts; Thiazoles; Trichloroacetic Acid; Tritium; Wound Healing | 1999 |
Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinoma; Cell Count; Cell Division; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Female; Fluorouracil; Gene Expression; Humans; Paclitaxel; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Taxoids; Telomerase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part II: characterization of antisense oligonucleotides loaded copolymer nanoparticles.
Topics: Animals; Chlorocebus aethiops; Colloids; Drug Carriers; Drug Screening Assays, Antitumor; Electrochemistry; Hemolysis; Hydrogen-Ion Concentration; Methacrylates; Microspheres; Oligonucleotides, Antisense; Particle Size; Polymers; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles; Vero Cells | 1999 |
In vitro drug-induced cytotoxicity predicts clinical response to high-dose chlorambucil in B-cell chronic lymphocytic leukemia.
Topics: Aged; Antineoplastic Agents, Alkylating; Cell Survival; Chlorambucil; Coloring Agents; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Multivariate Analysis; Neoplastic Stem Cells; Remission Induction; Tetrazolium Salts; Thiazoles; Treatment Outcome | 1999 |
[Comparative study of histopathological effects of preoperative chemotherapy using UFT and in vitro MTT assay of colonoscopy specimens from patients with colorectal cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonoscopy; Colorectal Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Tegafur; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uracil | 1999 |
Heterocyclic derivatives of all-trans retinoic acid: in vitro effects on fibroblast/keratinocyte growth and differentiation, and in vivo effects on guinea-pig skin.
Topics: Animals; Cell Differentiation; Child, Preschool; Coloring Agents; Fibroblasts; Fluorescent Antibody Technique; Guinea Pigs; Heterocyclic Compounds; Humans; Infant; Isomerism; Keratinocytes; Keratolytic Agents; Skin; Tetrazolium Salts; Thiazoles; Tretinoin | 1999 |
Recombinant human erythropoietin stimulates production of interleukin 2 by whole blood cell cultures of hemodialysis patients.
Topics: Adjuvants, Immunologic; Adult; Blood Cells; Cells, Cultured; Chromogenic Compounds; Chronic Disease; Colorimetry; Coloring Agents; Erythropoietin; Female; Glomerulonephritis; Humans; Interleukin-2; Leukocyte Count; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Recombinant Proteins; Renal Dialysis; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 1999 |
Shared antigenic epitopes and pathobiological functions of anti-p185(her2/neu) monoclonal antibodies.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Binding Sites, Antibody; Breast Neoplasms; Cell Transformation, Neoplastic; Cross Reactions; Epitopes; Female; Flow Cytometry; Humans; Immunoenzyme Techniques; Immunoglobulin Variable Region; Male; Mice; Models, Molecular; Prostatic Neoplasms; Rats; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Trastuzumab | 1999 |
A cytotoxic, apoptotic, low-molecular weight factor from pineal gland.
Topics: Animals; Annexin A5; Apoptosis; Biological Factors; Cell Separation; Cell Survival; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; In Situ Nick-End Labeling; K562 Cells; Molecular Weight; Monocytes; Pineal Gland; Propidium; Swine; Tetrazolium Salts; Thiazoles | 1999 |
Toxicity of protein aggregates in PC12 cells: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
Topics: Amyloid beta-Peptides; Animals; Coloring Agents; Macromolecular Substances; Oxidation-Reduction; PC12 Cells; Peptides; Rats; Tetrazolium Salts; Thiazoles | 1999 |
Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cell Count; Cerebral Cortex; Creatine Kinase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamate-Ammonia Ligase; Hippocampus; Humans; Mitochondria; Neurons; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spin Labels; Synaptosomes; Tetrazolium Salts; Thiazoles; Trypan Blue | 1999 |
Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Carbazoles; Carvedilol; Cell Survival; Daunorubicin; Humans; Inhibitory Concentration 50; Microscopy, Electron; Models, Chemical; Molecular Structure; Neurons; Polymers; Propanolamines; Protein Binding; Rolitetracycline; Structure-Activity Relationship; Tetrazolium Salts; Thermodynamics; Thiazoles; Tumor Cells, Cultured | 1999 |
Mechanisms of glucose hypersensitivity in beta-cells from normoglycemic, partially pancreatectomized mice.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Cells, Cultured; Coloring Agents; Electrophysiology; Glucose; Islets of Langerhans; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Pancreatectomy; Potassium Channels; Tetrazolium Salts; Thiazoles | 1999 |
Cellular toxicity of N-substituted 2,2'-dicarboxamidodiphenyldisulphides with high antimicrobial activity.
Topics: 3T3 Cells; Amides; Animals; Anti-Infective Agents; Cell Survival; Disulfides; L-Lactate Dehydrogenase; Mice; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 1999 |
The effect of mitomycin C after long-term storage on human Tenon's fibroblast proliferation.
Topics: Cell Division; Cells, Cultured; Cold Temperature; Drug Storage; Eye; Fibroblasts; Humans; Mitomycin; Tetrazolium Salts; Thiazoles | 1999 |
Toxic effects of mitomycin-C on cultured corneal keratocytes and endothelial cells.
Topics: Animals; Cell Survival; Cells, Cultured; Coloring Agents; Cornea; Dose-Response Relationship, Drug; Endothelium, Corneal; In Vitro Techniques; Keratins; Mitomycin; Swine; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors | 1999 |
Cytotoxicity of Au-based dental solders alone and on a substrate alloy.
Topics: Alloys; Animals; Cell Survival; Cells, Cultured; Dental Alloys; Dental Materials; Fibroblasts; Gold; Mice; Mice, Inbred BALB C; Palladium; Surface Properties; Tetrazolium Salts; Thiazoles | 1999 |
Antiproliferative effects of NO and ANP in cultured human airway smooth muscle.
Topics: Asthma; Atrial Natriuretic Factor; Blood Proteins; Cell Division; Cells, Cultured; Coloring Agents; Cyclic GMP; Diuretics; Hemoglobins; Hemostatics; Humans; Hyperplasia; Lung; Mitogens; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Peptide Fragments; Phosphodiesterase Inhibitors; Purinones; Tetrazolium Salts; Thiazoles; Thrombin; Vasodilator Agents | 1999 |
Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Size; Cell Survival; Ceramides; Dose-Response Relationship, Drug; Epithelial Cells; Female; Flow Cytometry; Humans; Insulin-Like Growth Factor Binding Proteins; Ligands; Oligopeptides; Somatomedins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Synergistic cytotoxicity of iodine-131-anti-CD20 monoclonal antibodies and chemotherapy for treatment of B-cell lymphomas.
Topics: Antibodies, Monoclonal; Antigens, CD20; Antineoplastic Agents; Burkitt Lymphoma; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Iodine Radioisotopes; Lymphoma, Large B-Cell, Diffuse; Radioimmunotherapy; Tetrazolium Salts; Thiazoles; Trypan Blue; Tumor Cells, Cultured | 2000 |
Cytoprotection and iron mobilization in rat hepatocyte cultures by a new synthetic dihydroxamate chelator.
Topics: Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Coloring Agents; Hydroxamic Acids; Iron; Iron Chelating Agents; Iron Radioisotopes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1999 |
Biphasic effect of cadmium in non-cytotoxic conditions on the secretion of nitric oxide from peritoneal macrophages.
Topics: Animals; Blotting, Western; Cadmium; Cell Separation; Cell Survival; Coloring Agents; In Vitro Techniques; Lipid Peroxidation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 1999 |
Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture.
Topics: Aldehydes; Amprolium; Animals; Apoptosis; Brain; Cell Death; Cells, Cultured; Coloring Agents; Ketoglutarate Dehydrogenase Complex; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Neurons; Oxidative Stress; Oxidoreductases; Tetrazolium Salts; Thiamine Deficiency; Thiazoles | 2000 |
Mercury induces cell cytotoxicity and oxidative stress and increases beta-amyloid secretion and tau phosphorylation in SHSY5Y neuroblastoma cells.
Topics: Amyloid beta-Peptides; Cell Survival; Drug Combinations; Glutathione; Melatonin; Mercuric Chloride; Neuroblastoma; Oxidative Stress; Peptide Fragments; Phosphorylation; tau Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Enhancement of NMDA-induced functional responses without concomitant NMDA receptor changes following chronic ethanol exposure in cerebellar granule cells.
Topics: Analysis of Variance; Animals; Apoptosis; Benzothiadiazines; Binding, Competitive; Blotting, Western; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Diuretics; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracellular Fluid; Long-Term Potentiation; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride Symporter Inhibitors; Tetrazolium Salts; Thiazoles | 1999 |
In vitro cytotoxicity of various forms of cobalt for rat alveolar macrophages and type II pneumocytes.
Topics: Animals; Cell Survival; Cells, Cultured; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; Edetic Acid; Lactalbumin; Lung; Macrophages, Alveolar; Male; Microscopy, Electron; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Tungsten Compounds | 2000 |
Synthesis and cytotoxicity of novel pyrido[1,2-e]purines on multidrug resistant human MCF7 cells.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Coloring Agents; Doxorubicin; Drug Resistance, Multiple; Humans; Purines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Immunomodulatory effect of arctigenin, a lignan compound, on tumour necrosis factor-alpha and nitric oxide production, and lymphocyte proliferation.
Topics: Adjuvants, Immunologic; Animals; B-Lymphocytes; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Endotoxins; Escherichia coli; Furans; Lignans; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1999 |
Oxidative stress and calcium homeostasis in dystrophic skin fibroblasts.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Adolescent; Calcium; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Hydrogen Peroxide; Isoenzymes; Male; Muscular Dystrophy, Duchenne; Oxidative Stress; Skin; Tetrazolium Salts; Thiazoles | 1999 |
In vitro augmentation of antitumor effect in combination with CPT-11 and CDDP for human colorectal cancer.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Coloring Agents; Drug Synergism; Female; Humans; Irinotecan; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Release of taurine in apoptotic cerebellar granule neurons in culture.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Size; Cell Survival; Cells, Cultured; Cerebellum; Chloride Channels; Coloring Agents; Diffusion; Enzyme Precursors; gamma-Aminobutyric Acid; Glutamic Acid; Membrane Potentials; Neurons; Potassium Chloride; Rats; Sodium; Taurine; Tetrazolium Salts; Thiazoles | 2000 |
Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Coloring Agents; DNA Fragmentation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Precursors; Flow Cytometry; Fluorescent Antibody Technique; Fluorometry; Humans; Indans; Microtubules; Neoplasms; Polymers; Protein Binding; Tetrazolium Salts; Thiazoles; Tubulin; Tumor Cells, Cultured | 2000 |
Angiotensin II type 1 receptor-mediated increase in cytosolic Ca(2+) and proliferation in mesothelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Buffers; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Division; Coloring Agents; Culture Media; Cytosol; Fluorescent Dyes; Fura-2; Indicators and Reagents; Nifedipine; Pertussis Toxin; Pleura; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazolium Salts; Thiazoles; Virulence Factors, Bordetella | 2000 |
Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.
Topics: Alzheimer Disease; Apoptosis; Brain Neoplasms; Cell Movement; Coloring Agents; Gene Deletion; Glucose; Humans; Hypertonic Solutions; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Membrane Proteins; Mutation; Neurites; Neuroblastoma; Osmotic Pressure; Presenilin-1; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2000 |
Axonal damage induced by cerebrospinal fluid from patients with relapsing-remitting multiple sclerosis.
Topics: Adolescent; Adult; Animals; Apoptosis; Axons; Cells, Cultured; Cerebrospinal Fluid; Coloring Agents; Humans; Metallothionein; Microscopy, Confocal; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Neurons; Rats; Tetrazolium Salts; Thiazoles | 2000 |
[Improved MTT colorimetric assay for serum TNF activity].
Topics: Animals; Colorimetry; Humans; L Cells; Mice; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 1997 |
Cytotoxicity of polymerized commercial cyanoacrylate adhesive on cultured human oral fibroblasts.
Topics: Adhesives; Cell Adhesion; Cell Movement; Cell Survival; Cells, Cultured; Coloring Agents; Cyanoacrylates; Denture Repair; Fibroblasts; Gentian Violet; Gingiva; Humans; Organic Chemicals; Polymers; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Adhesives | 1999 |
New isomalabaricane triterpenes from the marine sponge Stelletta globostellata that induce morphological changes in rat fibroblasts.
Topics: Acetylation; Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Coloring Agents; Fibroblasts; Porifera; Rats; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Triterpenes | 2000 |
Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?
Topics: Animals; Apoptosis; Cell Count; Cell Death; Cells, Cultured; Cerebral Cortex; Coloring Agents; Cycloheximide; Enzyme Inhibitors; Fetus; L-Lactate Dehydrogenase; Mice; Nerve Growth Factors; Neuroglia; Neurons; Neuroprotective Agents; Reproducibility of Results; Sphingosine; Tetrazolium Salts; Thiazoles; Trypan Blue | 2000 |
Studies in humans on the mechanism of potent spermicidal and apoptosis-inducing activities of vanadocene complexes.
Topics: Apoptosis; Biomechanical Phenomena; Blotting, Western; Coloring Agents; DNA Fragmentation; Dyneins; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Male; Membrane Potentials; Phosphates; Phosphotyrosine; Sperm Motility; Spermatocidal Agents; Spermatozoa; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vagina; Vanadium Compounds | 2000 |
Endothelial and smooth muscle changes of the thoracic and abdominal aorta with various types of cryopreservation.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Endothelium, Vascular; Immersion; In Vitro Techniques; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; Oxidation-Reduction; Oxygen Consumption; Swine; Tetrazolium Salts; Thiazoles; Tissue Survival | 2000 |
Cysteine chloromethyl and diazomethyl ketone derivatives with potent anti-leukemic activity.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Cell Line; Coloring Agents; Cysteine; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
The S-alkyl chain length as a determinant of the anti-leukemic activity of cysteine chloromethyl ketone compounds.
Topics: Alkylation; Antineoplastic Agents; Cell Line; Coloring Agents; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
[Predictive chemotherapy of breast cancer directed by MTT assay in vitro].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Tetrazolium Salts; Thiazoles | 1997 |
Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones.
Topics: Antineoplastic Agents; Benzylidene Compounds; Drug Screening Assays, Antitumor; Humans; Jurkat Cells; Magnetic Resonance Spectroscopy; Molecular Conformation; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil.
Topics: Antimetabolites, Antineoplastic; Biopsy; Coloring Agents; Dihydrouracil Dehydrogenase (NADP); Drug Resistance, Neoplasm; Fluorouracil; Humans; Oxidoreductases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Thymidylate Synthase | 2000 |
Apoptosis in human hepatoma cell line SMMC-7721 induced by water-soluble macromolecular components of Artemisia capillaris Thunberg.
Topics: Apoptosis; Artemisia; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Coloring Agents; Flow Cytometry; Humans; Microscopy, Electron; Microscopy, Phase-Contrast; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Water | 2000 |
Protection from cytotoxic effects induced by the nitrogen mustard mechlorethamine on human bronchial epithelial cells in vitro.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Bronchi; Cell Line; Cell Survival; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Humans; Iron Chelating Agents; Lipid Peroxidation; Mechlorethamine; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Prodrugs; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfoxides; Tetrazolium Salts; Thiazoles | 2000 |
Effect of brief exposure to mitomycin C on cultured human nasal mucosa fibroblasts.
Topics: Alkylating Agents; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; DNA; Fibroblasts; Flow Cytometry; Humans; In Situ Nick-End Labeling; Mitomycin; Nasal Mucosa; Tetrazolium Salts; Thiazoles | 2000 |
Activation of HSF and selective increase in heat-shock proteins by acute dexamethasone treatment.
Topics: Animals; Blotting, Western; Cell Hypoxia; Cells, Cultured; Chaperonin 60; Coloring Agents; Dexamethasone; Glucocorticoids; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; L-Lactate Dehydrogenase; Male; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
Protective effect of pyruvate upon cultured mesothelial cells exposed to 2 mM hydrogen peroxide.
Topics: Animals; Buffers; Cell Survival; Cells, Cultured; Dialysis Solutions; Epithelial Cells; Free Radical Scavengers; Hydrogen Peroxide; Peritoneal Dialysis; Peritoneum; Proteins; Pyruvic Acid; Rats; Tetrazolium Salts; Thiazoles | 2000 |
Irniine, a pyrrolidine alkaloid, isolated from Arisarum vulgare can induce apoptosis and/or necrosis in rat hepatocyte cultures.
Topics: Alkaloids; Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Damage; Electrophoresis, Agar Gel; Epithelial Cells; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Mitochondria; Necrosis; Neutral Red; Plants, Toxic; Pyrrolidines; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
Mutagenicity of recombinant antihemophilic factor (GC-gamma AHF).
Topics: Animals; Chromosome Aberrations; Cricetinae; Cricetulus; Factor VIII; Fibroblasts; Humans; Injections, Intraperitoneal; Lung; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; Mutagenicity Tests; Mutagens; Recombinant Proteins; Salmonella typhimurium; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2000 |
Toxicity of non-abeta component of Alzheimer's disease amyloid, and N-terminal fragments thereof, correlates to formation of beta-sheet structure and fibrils.
Topics: alpha-Synuclein; Alzheimer Disease; Amino Acid Sequence; Amyloid; Animals; Cell Survival; Circular Dichroism; Humans; Microscopy, Electron; Molecular Sequence Data; Nerve Tissue Proteins; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Protein Structure, Secondary; Rats; Solubility; Synucleins; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment.
Topics: Amyloid beta-Peptides; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Lithium Chloride; Neurons; Oxidation-Reduction; PC12 Cells; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Effect of sub-lethal concentrations of HEMA (2-hydroxyethyl methacrylate) on THP-1 human monocyte-macrophages, in vitro.
Topics: Analysis of Variance; Cell Division; Cells, Cultured; Coloring Agents; Humans; Indicators and Reagents; Macrophages; Methacrylates; Mitochondria; Monocytes; Pilot Projects; Proteins; Quinolines; Statistics as Topic; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2000 |
Protective effect of Hibiscus anthocyanins against tert-butyl hydroperoxide-induced hepatic toxicity in rats.
Topics: Alanine Transaminase; Animals; Anthocyanins; Aspartate Aminotransferases; Carcinogens; Cell Survival; Chemical and Drug Induced Liver Injury; Free Radicals; Glutathione; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malvaceae; Quinones; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
Myocardial ischemia-reperfusion injury in estrogen receptor-alpha knockout and wild-type mice.
Topics: Animals; Calcium; Coronary Circulation; Edema, Cardiac; Estrogen Receptor alpha; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Myocardial Ischemia; Myocardium; Nitrites; Receptors, Estrogen; Reperfusion Injury; Tetrazolium Salts; Thiazoles | 2000 |
Modulation of daunorubicin toxicity by liposomal encapsulation and use of specific inhibitors in vitro.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Humans; Liposomes; Rutin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Apoptosis induced by 2-chloro-adenosine and 2-chloro-2'-deoxy-adenosine in a human astrocytoma cell line: differential mechanisms and possible clinical relevance.
Topics: 2-Chloroadenosine; Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Cell Adhesion; Cell Division; Cell Line; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Cladribine; Coloring Agents; Culture Media; Flow Cytometry; Humans; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
APP carboxyl-terminal fragment without or with abeta domain equally induces cytotoxicity in differentiated PC12 cells and cortical neurons.
Topics: Amyloid beta-Protein Precursor; Animals; Cell Death; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebral Cortex; Coloring Agents; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Mutagenesis, Site-Directed; Neurons; PC12 Cells; Peptide Fragments; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
In vitro response of the brown bullhead catfish (BB) and rainbow trout (RTG-2) cell lines to benzo[a]pyrene.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzo(a)pyrene; Catfishes; Cell Line; Cytochrome P-450 CYP1A1; Environmental Monitoring; Neutral Red; Oncorhynchus mykiss; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 2000 |
Antioxidants prevent amyloid peptide-induced apoptosis and alteration of calcium homeostasis in cultured cortical neurons.
Topics: Amyloid; Animals; Antioxidants; Apoptosis; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Homeostasis; Indoles; Inositol 1,4,5-Trisphosphate; L-Lactate Dehydrogenase; Neurons; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
Effect of toluene diisocyanate and its corresponding amines on viability and growth of human lung fibroblasts in culture.
Topics: Asthma; Carcinogens; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cytotoxins; Fibroblasts; Humans; Hydrogen Peroxide; Lung; Occupational Diseases; Oxidants; Phenylenediamines; Tetrazolium Salts; Thiazoles; Toluene 2,4-Diisocyanate | 1999 |
Peptide YY and vitamin E inhibit hormone-sensitive and -insensitive breast cancer cells.
Topics: Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Cell Survival; Coloring Agents; Female; Humans; Peptide YY; Receptors, Estrogen; Tetrazolium Salts; Thiazoles; Tocopherols; Tumor Cells, Cultured; Vitamin E | 2000 |
Study on the cytotoxicity of microcystin-LR on cultured cells.
Topics: Cell Line; Cell Membrane; Cell Survival; Cyanobacteria; Enzyme Inhibitors; Eutrophication; L-Lactate Dehydrogenase; Marine Toxins; Microcystins; Peptides, Cyclic; Tetrazolium Salts; Thiazoles | 2000 |
Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.
Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Cell Death; Coloring Agents; Congo Red; Dose-Response Relationship, Drug; Fluorescent Dyes; Methylation; Microscopy, Electron; PC12 Cells; Peptide Biosynthesis; Peptide Fragments; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Rats; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2000 |
Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts.
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Blotting, Southern; Cell Division; Cytarabine; Cytidine Deaminase; DNA, Complementary; Drug Resistance, Neoplasm; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Glutathione Transferase; Humans; Mechlorethamine; Melphalan; Mice; Protein Biosynthesis; Rats; Retroviridae; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2000 |
Influence of lipid peroxidation on the nicotinic acetylcholine receptors in PC12 cells.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ferrous Compounds; Lipid Peroxides; Malondialdehyde; Nicotinic Agonists; Oxidation-Reduction; PC12 Cells; Pyridines; Rats; Receptors, Nicotinic; Tetrazolium Salts; Thiazoles | 2000 |
Synthesis and cytotoxic effects of deoxy-tomentellin.
Topics: 3T3 Cells; Animals; Antineoplastic Agents, Phytogenic; Benzoates; Cannabinoids; Cell Division; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Humans; KB Cells; Ketones; Mice; Rhodamines; Tetrazolium Salts; Thiazoles | 2000 |
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Apoptosis; Cell Survival; CHO Cells; Chromans; Cricetinae; Dimethyl Sulfoxide; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidative Stress; Peptide Fragments; Phosphatidylserines; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2000 |
Iron enhances hepatitis C virus replication in cultured human hepatocytes.
Topics: Cell Line, Transformed; Cell Survival; Coloring Agents; DNA Primers; Hepacivirus; Humans; Iron; Liver; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Tetrazolium Salts; Thiazoles; Virus Replication | 2000 |
Factors affecting hepatocyte viability and CYPIA1 activity during encapsulation.
Topics: Alginates; Animals; Apoptosis; Biocompatible Materials; Calcium; Calcium Chloride; Calcium Compounds; Cell Culture Techniques; Cell Survival; Coloring Agents; Cytochrome P-450 CYP1A1; Drug Compounding; Glutathione; Lactates; Liver; Necrosis; Nifedipine; Polylysine; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Reproducibility of Results; Swine; Taurine; Temperature; Tetrazolium Salts; Thiazoles | 2000 |
Toxin production in cyanobacterial mats from ponds on the McMurdo ice shelf, Antarctica.
Topics: Animals; Antarctic Regions; Bacterial Toxins; Biomass; Chromatography, High Pressure Liquid; Cyanobacteria; Enzyme Inhibitors; Fresh Water; Liver; Marine Toxins; Microcystins; Oncorhynchus mykiss; Peptides, Cyclic; Phosphoric Monoester Hydrolases; Tetrazolium Salts; Thiazoles; Trypan Blue | 2000 |
Comparison of two colorimetric assays to determine viral infectivity in micro culture virus titration.
Topics: Animals; Cell Line; Chlorocebus aethiops; Colorimetry; Cytopathogenic Effect, Viral; Dengue Virus; Evaluation Studies as Topic; Humans; Neutral Red; Poliovirus; Tetrazolium Salts; Thiazoles; Vero Cells; Virology | 1999 |
Evaluation of neurotoxicity of alzheimer's amyloid beta protein (beta42) in cultured hippocampal cells and its prevention by propentofylline.
Topics: Amyloid beta-Peptides; Animals; Cell Death; Cells, Cultured; Cyclic AMP; Drug Interactions; Exocytosis; Hippocampus; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Xanthines | 2000 |
[MTT-colorimetric method for detection the cytotoxic activity of human natural killer cells].
Topics: Colorimetry; Cytotoxicity, Immunologic; Humans; Immunologic Tests; K562 Cells; Killer Cells, Natural; Tetrazolium Salts; Thiazoles | 2000 |
Caspase-3 protease activation during the process of genistein-induced apoptosis in TM4 testicular cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Membrane Permeability; Enzyme Inhibitors; Genistein; Leydig Cells; Male; Microscopy, Fluorescence; Necrosis; Protein Kinase Inhibitors; Sertoli Cells; Tetrazolium Salts; Thiazoles; Trypan Blue | 2000 |
TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers.
Topics: Animals; Antigens, CD; Apoptosis; Catalase; Cells, Cultured; Glomerular Mesangium; Hydrogen Peroxide; Interleukin-1; Lipid Peroxidation; Malondialdehyde; Proto-Oncogene Proteins c-jun; Rats; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Second Messenger Systems; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
ET-18-OCH(3)-induced cytotoxicity and DNA damage in rat astrocytes.
Topics: Animals; Antineoplastic Agents; Astrocytes; Cell Survival; Cells, Cultured; Comet Assay; Culture Media, Conditioned; DNA; DNA Damage; Dose-Response Relationship, Drug; Fluoresceins; Glial Fibrillary Acidic Protein; L-Lactate Dehydrogenase; Lipid Peroxidation; Nitrates; Nitrites; omega-N-Methylarginine; Phospholipid Ethers; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2000 |
The clinical benefit of the histoculture drug response assay.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Neoplasms; Stomach Neoplasms; Survival Analysis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
The role of plasma membrane in bioreduction of two tetrazolium salts, MTT, and CTC.
Topics: Biological Transport; Cell Membrane; Fluorescein; Formazans; Humans; Kinetics; Microscopy, Confocal; Propidium; Tetrazoles; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2000 |
Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Carrier Proteins; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Serum-Free; Cytokines; DNA Fragmentation; Enzyme Inhibitors; Heart Ventricles; In Situ Nick-End Labeling; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2000 |
Comparative analysis of three methods to assess viability of mammalian cells in culture.
Topics: Animals; Cell Culture Techniques; Cell Survival; Chlorocebus aethiops; Coloring Agents; Humans; L-Lactate Dehydrogenase; Liver; Mammals; Tetrazolium Salts; Thiazoles; Trypan Blue; Vero Cells | 1999 |
Cytotoxicity assessment of Ma-huang (Ephedra) under different conditions of preparation.
Topics: Cell Survival; Colorimetry; Drugs, Chinese Herbal; Ephedra sinica; Ephedrine; Humans; Liver; Plant Preparations; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Bovine seminal ribonuclease attached to nanoparticles made of polylactic acid kills leukemia and lymphoma cell lines in vitro.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Division; Dose-Response Relationship, Drug; Drug Carriers; Endoribonucleases; Fibroblasts; Humans; Lactic Acid; Leukemia; Lymphoma; Male; Mice; Mice, Inbred ICR; Microspheres; Polyesters; Polymers; Spermatozoa; Testis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Discrimination between NK and LAK cytotoxic activities of murine spleen cells by MTT assay: differential inhibition by PGE(2) and EDTA.
Topics: Animals; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Dinoprostone; Edetic Acid; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; Spleen; Tetrazolium Salts; Thiazoles | 2000 |
Cytotoxicity, apoptosis, and viral replication in tumor cells treated with oncolytic ribonucleotide reductase-defective herpes simplex type 1 virus (hrR3) combined with ionizing radiation.
Topics: Apoptosis; Cell Survival; Combined Modality Therapy; Defective Viruses; Female; Flow Cytometry; Glioblastoma; Herpesvirus 1, Human; Humans; Pancreatic Neoplasms; Radiation Dosage; Radiation, Ionizing; Ribonucleotide Reductases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Virus Replication | 2000 |
In vitro studies of the phototoxic potential of the antidepressant drugs amitriptyline and imipramine.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cells, Cultured; Chromatography, High Pressure Liquid; Coloring Agents; Dermatitis, Phototoxic; DNA; DNA Damage; Erythrocytes; Fibroblasts; Hemolysis; Imipramine; Linoleic Acid; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Photochemistry; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2000 |
Comparison of NCCLS and 3-(4,5-dimethyl-2-Thiazyl)-2, 5-diphenyl-2H-tetrazolium bromide (MTT) methods of in vitro susceptibility testing of filamentous fungi and development of a new simplified method.
Topics: Antifungal Agents; Formazans; Humans; Microbial Sensitivity Tests; Mitosporic Fungi; Mycoses; Oxidation-Reduction; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 2000 |
Metabolic activity of cultured rat brainstem, hippocampal and spinal cord slices.
Topics: Animals; Animals, Newborn; Brain; Brain Stem; Cell Survival; Coloring Agents; Hippocampus; Mitochondria; Organ Culture Techniques; Rats; Spinal Cord; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Functional assessment in vitro of human-complement-dependent antibody-induced cytotoxicity of neoplastic cells.
Topics: Animals; Antibodies, Monoclonal; Cell Death; Cell Division; Chemistry, Clinical; Complement C3c; Complement C4; Complement System Proteins; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; G(M1) Ganglioside; Humans; Immunoglobulin G; Mice; Neoplasms; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2000 |
CREB-binding protein sequestration by expanded polyglutamine.
Topics: Animals; Ataxin-3; Cell Death; Cell Line; Cell Nucleus; Cells, Cultured; CREB-Binding Protein; DNA-Binding Proteins; Fungal Proteins; Green Fluorescent Proteins; HeLa Cells; Humans; Luciferases; Luminescent Proteins; Machado-Joseph Disease; Male; Mice; Mice, Transgenic; Muscular Atrophy, Spinal; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Repressor Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Scrotum; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Trinucleotide Repeat Expansion | 2000 |
Highly stereoselective synthesis and biological properties of nucleoside analogues bearing a spiro inserted oxirane ring.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Survival; Cytomegalovirus; Ethylene Oxide; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV; Humans; Molecular Structure; Nucleosides; Spiro Compounds; Stereoisomerism; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy.
Topics: Adenosine Triphosphate; Antioxidants; bcl-2-Associated X Protein; bcl-X Protein; Brain Diseases; Calcium; Deferoxamine; Dinitrobenzenes; Electrophysiology; Glioma; Humans; Mitochondria; Neuroblastoma; Oxidation-Reduction; Permeability; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Trifluoperazine; Tumor Cells, Cultured; Vitamin E | 2000 |
Inhibition of lipopolysaccharide-induced I-kappaB degradation and tumor necrosis factor-alpha expression by acriflavine, an antimicrobial agent.
Topics: Acriflavine; Animals; Anti-Infective Agents, Local; Cell Line; Densitometry; DNA Probes; Enzyme-Linked Immunosorbent Assay; I-kappa B Proteins; Immunoblotting; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Electrochemistry; Lactic Acid; Mice; Microscopy, Confocal; Microspheres; Neoplasm Transplantation; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 2000 |
Cytokine-induced impairment of short-chain fatty acid oxidation and viability in human colonic epithelial cells.
Topics: Apoptosis; Butyrates; Carbon Dioxide; Cell Death; Cell Line; Colon; Coloring Agents; Cytokines; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Epithelial Cells; Fatty Acids, Volatile; Humans; Interferon-gamma; Interleukin-1; Microscopy, Electron; Nitric Oxide; Oxygen; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Designed cyclopentenone prostaglandin derivatives as neurite outgrowth-promoting compounds for CAD cells, a rat catecholaminergic neuronal cell line of the central nervous system.
Topics: Animals; Cell Differentiation; Cell Line; Cell Survival; Cyclopentanes; Dose-Response Relationship, Drug; Drug Design; Neurites; Neurons; Prostaglandins A; Rats; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2000 |
Cytotoxicity of the MEIC reference chemicals in rat hepatoma-derived Fa32 cells.
Topics: Animals; Glutathione; Humans; Liver Neoplasms, Experimental; Neutral Red; Rats; Tetrazolium Salts; Thiazoles; Toxicology; Tumor Cells, Cultured | 2000 |
Cytotoxicity of aphidicolin and its derivatives against neuroblastoma cells in vitro: synergism with doxorubicin and vincristine.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aphidicolin; Cell Survival; Doxorubicin; Drug Synergism; Enzyme Inhibitors; Humans; Molecular Structure; Neuroblastoma; Nucleic Acid Synthesis Inhibitors; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 2000 |
Hormesis: a stress response in cells exposed to low levels of heavy metals.
Topics: Algorithms; Animals; Cadmium; Cells, Cultured; Colorimetry; Coloring Agents; HSP70 Heat-Shock Proteins; Metallothionein; Metals, Heavy; Mice; Mutation; Proteins; Stimulation, Chemical; Stress, Physiological; Tetrazolium Salts; Thiazoles | 2000 |
Arsenic trioxide inhibits neuroblastoma growth in vivo and promotes apoptotic cell death in vitro.
Topics: Antigens, Differentiation; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Caspase Inhibitors; Caspases; Cell Differentiation; Cell Division; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasm Transplantation; Neuroblastoma; Oxides; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tretinoin; Tumor Cells, Cultured | 2000 |
Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans.
Topics: Androstadienes; Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Coloring Agents; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Indicators and Reagents; Insulin-Like Growth Factor I; Interferon-gamma; Interleukin-1; Islets of Langerhans; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphorylation; Propidium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha; Wortmannin | 2000 |
Escape from apoptosis after prolonged serum deprivation is associated with the regulation of the mitochondrial death pathway by Bcl-x(l).
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cell Division; Cell Line; Coloring Agents; Culture Media, Serum-Free; Cytochrome c Group; Cytosol; Dogs; Mitochondria; Mitosis; Precipitin Tests; Proliferating Cell Nuclear Antigen; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Colorimetric determination of inhibition of hematopoietic progenitor cells in soft agar.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Colony-Forming Units Assay; Colony-Stimulating Factors; Colorimetry; Coloring Agents; Cytarabine; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Ganciclovir; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tetrazolium Salts; Thiazoles; Zidovudine | 2000 |
Real time monitoring of lymphocyte proliferation by an impedance method.
Topics: Cell Division; Colony-Forming Units Assay; Electric Impedance; Humans; Lymphocyte Activation; Lymphocytes; Monitoring, Immunologic; Phytohemagglutinins; Tetrazolium Salts; Thiazoles | 2000 |
Cryopreserved rat liver slices: a critical evaluation of cell viability, histological integrity, and drug-metabolizing enzymes.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Antipyrine; Apoptosis; Biotransformation; Cell Survival; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Glutathione; Hepatocytes; Insulin; Liver; Male; Organ Culture Techniques; Organ Preservation Solutions; Oxidation-Reduction; Proteins; Raffinose; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2000 |
Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Nucleus; Cell Separation; Cells, Cultured; Chick Embryo; Culture Media, Serum-Free; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heart; In Situ Nick-End Labeling; Mice; Myocardium; Necrosis; Propidium; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Prolonged exposure to hyperbaric oxygen induces neuronal damage in primary rat cortical cultures.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hyperbaric Oxygenation; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen; Pressure; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles | 2000 |
High conservation of both phase I and II drug-metabolizing activities in cryopreserved rat liver slices.
Topics: Amides; Animals; Cryopreservation; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Hydroxylation; Isoenzymes; Liver; Male; Mitochondria, Liver; Naphthols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Ropivacaine; Testosterone; Tetrazolium Salts; Thiazoles | 2000 |
2,2',4,6,6'-pentachlorobiphenyl induces apoptosis in human monocytic cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Nucleus; Cell Survival; Cells, Cultured; Coloring Agents; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Environmental Pollutants; Humans; Liver Neoplasms; Monocytes; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Tetrazolium Salts; Thiazoles; Trypan Blue; U937 Cells | 2000 |
A nonfibrillar form of the fusogenic prion protein fragment [118-135] induces apoptotic cell death in rat cortical neurons.
Topics: Amino Acid Chloromethyl Ketones; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; L-Lactate Dehydrogenase; Membrane Fusion; Neurons; Peptide Fragments; Prions; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2000 |
Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein.
Topics: alpha-Synuclein; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Immunoblotting; Kidney; Mutation; Nerve Tissue Proteins; Neurons; Oxidative Stress; Parkinson Disease; Reactive Oxygen Species; RNA, Messenger; Sulfhydryl Compounds; Synucleins; Tetrazolium Salts; Thiazoles; Transfection; Vitamin K | 2000 |
Cytotoxicity of PM(2.5) and PM(2.5--10) ambient air pollutants assessed by the MTT and the Comet assays.
Topics: Aerosols; Air Pollutants; Animals; Cell Line; Cell Survival; Comet Assay; DNA; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Mutagens; Organic Chemicals; Particle Size; Rats; Seasons; Solubility; Tetrazolium Salts; Thiazoles | 2000 |
Ex vivo antisense oligonucleotides to proliferating cell nuclear antigen and Cdc2 kinase inhibit graft coronary artery disease.
Topics: Actins; Animals; CDC2 Protein Kinase; Cell Division; Cells, Cultured; Coronary Disease; Disease Models, Animal; Heart Transplantation; Humans; Immunohistochemistry; Macrophages; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Polymerase Chain Reaction; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred ACI; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
In vitro and human testing strategies for skin irritation.
Topics: Animals; Aspartate Aminotransferases; Cell Survival; Clinical Trials as Topic; Deodorants; Humans; Irritants; L-Lactate Dehydrogenase; Organ Culture Techniques; Patch Tests; Rabbits; Reagent Kits, Diagnostic; Reproducibility of Results; Risk Assessment; Skin; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles | 2000 |
Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats.
Topics: Animals; Calcium; Coloring Agents; Coronary Circulation; Estradiol; Female; In Vitro Techniques; Microscopy, Electron; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitrites; Ovariectomy; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Ventricular Function, Left; Ventricular Pressure | 2000 |
Drug-induced cytotoxicity in tissue culture.
Topics: Agar; Animals; Antineoplastic Agents; Cell Count; Cell Death; Cell Division; Cell Line; Cell Survival; Clone Cells; DNA; DNA Damage; DNA Topoisomerases, Type II; Tetrazolium Salts; Thiazoles; Topoisomerase II Inhibitors | 2001 |
PrP fragment 106-126 is toxic to cerebral endothelial cells expressing PrP(C).
Topics: Amino Acid Sequence; Animals; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Endothelium; Enzyme Inhibitors; Fluorescent Dyes; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Pentosan Sulfuric Polyester; Peptide Fragments; Prions; Tetrazolium Salts; Thiazoles | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Antioxidant compounds interfere with the 3.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E | 2000 |
Synergistic potentiating effect of D(+)-mannose, orotic, and hippuric acid sodium salt on selective toxicity of a mixture of 13 substances of the circulatory system in culture for various tumor cell lines.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Line; Colorimetry; Dogs; Drug Resistance, Multiple; Hippurates; Humans; Macaca mulatta; Mannose; Mice; Multiple Myeloma; Neoplasms, Experimental; Orotic Acid; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Setting of a colorimetric method to determine the viability of Trypanosoma cruzi epimastigotes.
Topics: Animals; Colorimetry; Culture Media; Nifurtimox; Nitroimidazoles; Oxidation-Reduction; Parasitic Sensitivity Tests; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Trypanocidal Agents; Trypanosoma cruzi | 2000 |
Beta-amyloid (1-42) affects MTT reduction in astrocytes: implications for vesicular trafficking and cell functionality.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Biological Transport; Cell Survival; Cells, Cultured; Coloring Agents; Intracellular Membranes; Kinetics; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2001 |
Antioxidant activity related to copper binding of native prion protein.
Topics: Animals; Antioxidants; Cations, Divalent; Cells, Cultured; Chromatography, Affinity; Copper; Cytochrome c Group; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Mice; Oxidative Stress; Peptide Fragments; Prions; PrPC Proteins; Spectrometry, X-Ray Emission; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2001 |
N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylation.
Topics: Acetylcysteine; Amyloid beta-Peptides; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutathione; Glutathione Reductase; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidative Stress; Peptide Fragments; Phosphorylation; tau Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells.
Topics: Alkaloids; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Butyrates; Carcinoma; Cell Nucleus; Colonic Neoplasms; Coloring Agents; Cyclic P-Oxides; Cytoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Microscopy, Fluorescence; Neoplasm Proteins; Nicotinic Acids; RNA, Catalytic; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 2001 |
Chemopreventive effects of grape seed proanthocyanidin extract on Chang liver cells.
Topics: Anthocyanins; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Chemoprevention; Cyclophosphamide; DNA Primers; Flow Cytometry; Hepatocytes; Humans; Idarubicin; Plant Extracts; Proanthocyanidins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA; Rosales; Seeds; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2000 |
Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Butylated Hydroxyanisole; Carcinogens; Cisplatin; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Flow Cytometry; Humans; Male; Ovarian Neoplasms; Oxides; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Truncation of the extracellular region abrogrates cell contact but retains the growth-suppressive activity of E-cadherin.
Topics: alpha Catenin; Animals; beta Catenin; Cadherins; Cell Adhesion; Cell Communication; Cell Division; Cell Survival; Coloring Agents; Contact Inhibition; Cytoplasm; Cytoskeletal Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Genes, Reporter; Immunoblotting; Male; Mice; Mutation; Neoplasms; Precipitin Tests; Prostatic Neoplasms; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription, Genetic; Transfection | 2000 |
Measurement of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT.
Topics: Animals; Animals, Newborn; Astrocytes; Biological Assay; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Culture Media; Cytotoxins; Formazans; L-Lactate Dehydrogenase; Neurons; Oxidation-Reduction; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2000 |
Adult human olfactory stem cells.
Topics: Aged; Aged, 80 and over; Bucladesine; Cell Culture Techniques; Cell Division; Cell Survival; Coloring Agents; Female; Humans; Male; Microscopy, Electron; Middle Aged; Olfactory Mucosa; Olfactory Receptor Neurons; Receptor, trkA; Receptor, trkB; Receptor, trkC; Stem Cells; Tetrazolium Salts; Thiazoles | 2001 |
Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells.
Topics: Analgesics, Non-Narcotic; Biological Transport, Active; Caco-2 Cells; Calcium; Chemical Phenomena; Chemistry, Physical; Clodronic Acid; Humans; Intestinal Absorption; Lipids; Molecular Weight; Tetrazolium Salts; Thiazoles | 2001 |
Leflunomide inhibits activation of inducible nitric oxide synthase in rat astrocytes.
Topics: Animals; Astrocytes; Astrocytoma; Cell Line; Enzyme Activation; Immunosuppressive Agents; Indicators and Reagents; Interferon-gamma; Isoxazoles; Leflunomide; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein-Tyrosine Kinases; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2001 |
NO as an autocrine mediator in the apoptosis of activated microglial cells: correlation between activation and apoptosis of microglial cells.
Topics: Animals; Apoptosis; Autocrine Communication; Blotting, Western; Cells, Cultured; DNA; Electrophoresis, Agar Gel; Enzyme Inhibitors; Lipopolysaccharides; Microglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
Cytotoxicity of fluoride on human pulp cell cultures in vitro.
Topics: Analysis of Variance; Bisbenzimidazole; Cariostatic Agents; Cell Division; Cells, Cultured; Colorimetry; Coloring Agents; Dental Pulp; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Fluorides; Humans; Leucine; Mitochondria; Protein Biosynthesis; Proteins; Radiopharmaceuticals; Reproducibility of Results; Statistics as Topic; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 2001 |
Selective killing of human immunodeficiency virus-infected cells by targeted gene transfer and inducible gene expression using a recombinant human immunodeficiency virus vector.
Topics: Animals; Antiviral Agents; CD4-Positive T-Lymphocytes; Cell Death; Cell Line; Coloring Agents; COS Cells; Dose-Response Relationship, Drug; Ganciclovir; Gene Transfer Techniques; Genetic Vectors; HeLa Cells; HIV Infections; HIV-1; Humans; Models, Genetic; Plasmids; Ribonucleases; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Time Factors | 2001 |
Down-regulation of catalase gene expression in the doxorubicin-resistant AML subline AML-2/DX100.
Topics: Antineoplastic Agents; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Catalase; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Glucosephosphate Dehydrogenase; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Oxidants; Paraquat; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Increased cytotoxicity of food-borne mycotoxins toward human cell lines in vitro via enhanced cytochrome p450 expression using the MTT bioassay.
Topics: Biological Assay; Cell Line, Transformed; Cell Survival; Cytochrome P-450 Enzyme System; Food Contamination; Humans; Mycotoxins; Tetrazolium Salts; Thiazoles | 1999 |
Beta-VLDL protects against A beta(1-42) and apoE toxicity in human SH-SY5Y neuroblastoma cells.
Topics: Amyloid beta-Peptides; Apolipoproteins E; Coloring Agents; Fibroblasts; Humans; Lipoproteins, VLDL; Neuroblastoma; Neurons; Neuroprotective Agents; Peptide Fragments; Skin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Acidic pH promotes the formation of toxic fibrils from beta-amyloid peptide.
Topics: Acids; Amyloid; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Fluorescent Dyes; Hydrogen-Ion Concentration; Macromolecular Substances; Microscopy, Fluorescence; PC12 Cells; Peptide Fragments; Phosphatidylserines; Rats; Tetrazolium Salts; Thiazoles | 2001 |
Androgen-induced oxidative stress in human LNCaP prostate cancer cells is associated with multiple mitochondrial modifications.
Topics: Antimycin A; Coloring Agents; DNA; Electron Transport; Fluoresceins; Fluorescent Dyes; Humans; Hydroxyl Radical; Male; Metribolone; Mitochondria; Oxidative Stress; Peroxides; Prostatic Neoplasms; Rotenone; Testosterone Congeners; Tetrazolium Salts; Thiazoles; Time Factors; Tocopherols; Tumor Cells, Cultured; Uncoupling Agents; Vitamin E | 1999 |
Antitumor effects of the combination therapy with TNF-alpha gene-modified tumor cells and interleukin 12 in a melanoma model in mice.
Topics: Animals; Drug Therapy, Combination; Flow Cytometry; Genetic Therapy; Humans; Immunity, Cellular; Interferon-gamma; Interleukin-12; Major Histocompatibility Complex; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Retroviridae; Spleen; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
An iron-regulated ferric reductase associated with the absorption of dietary iron.
Topics: Amino Acid Sequence; Anemia; Animals; Cell Line; Cloning, Molecular; Cytochrome b Group; DNA, Complementary; Duodenum; Enterocytes; Enzyme Induction; Ferric Compounds; Hypoxia; Intestinal Absorption; Intestinal Mucosa; Iron, Dietary; Male; Mice; Microvilli; Molecular Sequence Data; Nitroblue Tetrazolium; Oocytes; Oxidation-Reduction; Oxidoreductases; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation; Xenopus | 2001 |
Assessment of the antitumour activity of targeted immunospecific albumin microspheres loaded with cisplatin and 5-fluorouracil: toxicity against a rodent ovarian carcinoma in vitro.
Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Fluorouracil; Humans; Microspheres; Ovarian Neoplasms; Rats; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Effect of low dose irradiation on estrogen receptor level in MCF-7 breast cancer cells.
Topics: Binding Sites; Blotting, Western; Breast Neoplasms; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Electrophoresis, Polyacrylamide Gel; Estradiol; Humans; Immunohistochemistry; Pregnenediones; Protein Binding; Receptors, Estrogen; Receptors, Progesterone; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Expression of transduced HSP70 gene protects chondrocytes from stress.
Topics: Adenoviridae; Biological Assay; Cells, Cultured; Chondrocytes; Coloring Agents; Gene Expression Regulation, Viral; Genetic Therapy; Genetic Vectors; HSP70 Heat-Shock Proteins; Humans; Osteoarthritis; Oxazines; Stress, Physiological; Tetrazolium Salts; Thiazoles; Transduction, Genetic; Xanthenes | 2001 |
In vitro biocompatibility of resorbable experimental glass ceramics for bone substitutes.
Topics: 3T3 Cells; Animals; Biodegradation, Environmental; Bone Substitutes; Cell Line; Ceramics; Coloring Agents; In Vitro Techniques; Materials Testing; Mice; Solubility; Surface Properties; Tetrazolium Salts; Thiazoles | 2001 |
Radiation-induced DNA damage and repair evaluated with 'comet assay' in human ovarian carcinoma cell lines with different radiosensitivities.
Topics: Apoptosis; Cell Cycle; Coloring Agents; Comet Assay; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Female; Flow Cytometry; Humans; Kinetics; Ovarian Neoplasms; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; X-Rays | 2000 |
Diazenes as modificators of drug-resistance in tumor cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Glutathione; HeLa Cells; Humans; Imides; Models, Chemical; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 2000 |
Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo.
Topics: Animals; Apoptosis; Azacitidine; Caspase 1; Cell Division; Coloring Agents; Decitabine; DNA Methylation; DNA, Complementary; Enzyme Inhibitors; fas Receptor; Gene Silencing; Genetic Vectors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
t-Butyl hydroperoxide and oxidized low density lipoprotein enhance phospholipid hydrolysis in lipopolysaccharide-stimulated retinal pericytes.
Topics: Animals; Cattle; Cells, Cultured; Coloring Agents; DNA Fragmentation; Hydrolysis; Lipopolysaccharides; Lipoproteins, LDL; Microscopy, Electron; Oxidants; Oxidative Stress; Pericytes; Phospholipids; Retina; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 2001 |
Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells.
Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Cell Membrane; Cell Nucleus; Cell Survival; Chromones; Colforsin; Coloring Agents; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; MAP Kinase Signaling System; Models, Biological; Morpholines; PC12 Cells; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2001 |
Molecular consequences of activated microglia in the brain: overactivation induces apoptosis.
Topics: Animals; Annexin A5; Apoptosis; Astrocytes; Brain; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Clusterin; DNA Fragmentation; Dose-Response Relationship, Drug; Glycoproteins; In Situ Nick-End Labeling; Lipopolysaccharides; Microglia; Molecular Chaperones; Rats; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) causes Akt phosphorylation and morphological changes in intracellular organellae in cultured rat astrocytes.
Topics: Animals; Astrocytes; Cell Compartmentation; Cell Membrane; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Immunohistochemistry; Intracellular Fluid; Membrane Proteins; Organelles; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rab5 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Vesicular Transport Proteins | 2001 |
Adverse effects of arecoline and nicotine on human periodontal ligament fibroblasts in vitro.
Topics: Areca; Arecoline; Cell Death; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fibroblasts; Humans; Nicotine; Periodontal Ligament; Plants, Medicinal; Protein Biosynthesis; Proteins; Statistics as Topic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 2001 |
Evaluation of GL331 in combination with paclitaxel: GL331's interference with paclitaxel-induced cell cycle perturbation and apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cyclin B; Cyclin B1; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Etoposide; Flow Cytometry; Fungal Proteins; Humans; Nasopharyngeal Neoplasms; Nuclear Proteins; Paclitaxel; Precipitin Tests; Protein Kinases; Tetrazolium Salts; Thiazoles; Toxicity Tests; Tumor Cells, Cultured | 2001 |
An evaluation of the colorimetric assays based on enzymatic reactions used in the measurement of human natural cytotoxicity.
Topics: Chromium Radioisotopes; Colorimetry; Coloring Agents; Cytotoxicity Tests, Immunologic; Glycoside Hydrolases; Humans; In Vitro Techniques; Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; beta-Galactosidase; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Dexamethasone; Drug Synergism; Electrophoresis, Agar Gel; Flow Cytometry; Genistein; Humans; Liver Neoplasms; Luciferases; Promoter Regions, Genetic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2001 |
Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoprotein A-I; Enzyme-Linked Immunosorbent Assay; Extracellular Space; Humans; Mutagenesis, Site-Directed; Oxidation-Reduction; PC12 Cells; Protein Structure, Tertiary; Rats; Sodium Dodecyl Sulfate; Tetrazolium Salts; Thiazoles; Two-Hybrid System Techniques | 2001 |
CD40-CD40 ligand (CD154) engagement is required but not sufficient for modulating MHC class I, ICAM-1 and Fas expression and proliferation of human non-small cell lung tumors.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; CD40 Antigens; CD40 Ligand; Cell Cycle; Cell Division; Coloring Agents; Cross-Linking Reagents; Dose-Response Relationship, Drug; fas Receptor; Flow Cytometry; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung Neoplasms; Major Histocompatibility Complex; Phenotype; Recombinant Fusion Proteins; S Phase; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
Potentiation of arsenic-induced cytotoxicity by sulfur amino acid deprivation (SAAD) through activation of ERK1/2, p38 kinase and JNK1: the distinct role of JNK1 in SAAD-potentiated mercury toxicity.
Topics: Amino Acids, Sulfur; Animals; Arsenic; Cell Survival; Enzyme Activation; In Situ Nick-End Labeling; Mercury; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Poisons; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Alteration of Fas/FasL expression of oral squamous cell carcinoma cell line Tca83 induced by retinoic acid.
Topics: Antigens, Surface; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coloring Agents; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Ligands; Membrane Glycoproteins; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Tongue Neoplasms; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 2000 |
DNA-liposome complexes transduction of herpes simplex virus thymidine kinase renders human tongue cancer cell line sensitive to ganciclovir in vitro.
Topics: Antineoplastic Agents; Antiviral Agents; Carcinoma, Mucoepidermoid; Cell Death; Coloring Agents; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Ganciclovir; Genetic Therapy; Humans; In Situ Hybridization; Liposomes; Polymerase Chain Reaction; Prodrugs; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Time Factors; Tongue Neoplasms; Transduction, Genetic; Trypan Blue; Tumor Cells, Cultured | 2000 |
In vitro cytotoxicity evaluation of denture adhesive.
Topics: Adhesives; Adolescent; Adult; Biocompatible Materials; Cell Division; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Child; Coloring Agents; Denture Retention; Fibroblasts; Humans; Periodontium; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2000 |
Actions of bovine plasma fibronectin on cultured human dental pulp cells.
Topics: Alkaline Phosphatase; Animals; Cattle; Cell Adhesion; Cell Division; Cell Movement; Cell Size; Cells, Cultured; Collagen; Coloring Agents; Concanavalin A; Dental Pulp; DNA; Extracellular Matrix Proteins; Fibronectins; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Molar, Third; Radiopharmaceuticals; Statistics as Topic; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Wheat Germ Agglutinins | 2000 |
Cytotoxicity of dental glass ionomers evaluated using dimethylthiazol diphenyltetrazolium and neutral red tests.
Topics: Aluminum; Animals; Arsenic; Cell Survival; Cells, Cultured; Cermet Cements; Coloring Agents; Culture Media; Dental Cements; Fibroblasts; Fluorides; Glass Ionomer Cements; Lead; Materials Testing; Mice; Neutral Red; Resins, Synthetic; Tetrazolium Salts; Thiazoles | 2001 |
Trimethyltin reduces ATP levels and MTT reduction in the LRM55 rat astrocytoma cell line.
Topics: Adenosine Triphosphate; Animals; Astrocytoma; Coloring Agents; L-Lactate Dehydrogenase; Oxidation-Reduction; Rats; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds; Tumor Cells, Cultured | 2000 |
Effects of triclosan on the cytotoxicity and fungal growth on a soft denture liner.
Topics: Analysis of Variance; Animals; Anti-Infective Agents, Local; Antifungal Agents; Bromine; Candida albicans; Cell Line; Colony Count, Microbial; Coloring Agents; Denture Liners; Disinfectants; Drug Combinations; Fibroblasts; Fluorocarbons; Methacrylates; Mice; Mice, Inbred BALB C; Phenols; Polyesters; Quaternary Ammonium Compounds; Saliva, Artificial; Statistics as Topic; Tetrazolium Salts; Thiazoles; Triclosan | 2001 |
Thrombin-stimulated growth, clustering, and collagen lattice contraction of human gingival fibroblasts is associated with its protease activity.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Cell Aggregation; Cell Division; Cells, Cultured; Collagen; Coloring Agents; Crystallization; Cytochalasin B; Dinoprostone; Enzyme Activation; Fibroblasts; Gene Expression; Gingiva; Humans; Peptide Fragments; Receptor, PAR-1; Receptor, PAR-2; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine Proteinase Inhibitors; Serum Albumin, Bovine; Statistics as Topic; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors; Trypsin | 2001 |
Sensitivity of human pancreatic adenocarcinoma tumor lines to chemotherapy, radiotherapy, and hyperthermia.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Hyperthermia, Induced; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Polyamide 6 composite membranes: properties and in vitro biocompatibility evaluation.
Topics: 3T3 Cells; Animals; Antigens, CD; B7-2 Antigen; Biocompatible Materials; Caprolactam; Cell Division; Cell Membrane; Cell Separation; Chondroitin Sulfates; Coloring Agents; DNA Damage; Flow Cytometry; Gelatin; Humans; Leukocyte Common Antigens; Lipopolysaccharide Receptors; Lymphocytes; Macrophage-1 Antigen; Membrane Glycoproteins; Membranes, Artificial; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Neutral Red; Polymers; Spleen; Tetrazolium Salts; Thiazoles | 2001 |
Assay of sperm quality in the domestic fowl by MTT reduction.
Topics: Animals; Colorimetry; Fertilization; Formazans; Male; Oxidation-Reduction; Poultry; Semen; Sperm Motility; Spermatozoa; Tetrazolium Salts; Thiazoles | 2001 |
Application of an MTT reduction assay for assessing sperm quality and predicting fertilising ability of domestic fowl semen.
Topics: Animals; Colorimetry; Fertilization; Formazans; Male; Oxidation-Reduction; Poultry; Semen; Sperm Motility; Spermatozoa; Tetrazolium Salts; Thiazoles | 2001 |
Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Coloring Agents; Convulsants; Cyclic N-Oxides; Dicarboxylic Acids; Energy Metabolism; Enzyme Inhibitors; Glutamic Acid; Mitochondria; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Nitrogen Oxides; Propionates; Pyrrolidines; Rats; Rats, Wistar; Sodium Azide; Tetrazolium Salts; Thiazoles; Vitamin E | 2001 |
Anti-oxidant effects of the extracts from the leaves of Chromolaena odorata on human dermal fibroblasts and epidermal keratinocytes against hydrogen peroxide and hypoxanthine-xanthine oxidase induced damage.
Topics: Antioxidants; Cell Division; Cell Survival; Cells, Cultured; Dermis; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Humans; Hydrogen Peroxide; Keratinocytes; Oxidants; Phenols; Plant Extracts; Plants, Medicinal; Polymers; Polyphenols; Tetrazolium Salts; Thiazoles; Xanthine Oxidase | 2001 |
Effect of inhibitors of cysteine and serine proteases in anticancer drug-induced apoptosis in gastric cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Humans; Serine Endopeptidases; Serine Proteinase Inhibitors; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Coloring Agents; Curcumin; Cytosol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Genetic Vectors; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Immunoblotting; Inhibitory Concentration 50; Isoenzymes; Liver; Multidrug Resistance-Associated Proteins; Phenotype; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured; Verapamil | 2001 |
Bispecific antibody targeting of doxorubicin to carcinoembryonic antigen-expressing colon cancer cell lines in vitro and in vivo.
Topics: Animals; Antibodies, Bispecific; Antineoplastic Agents; Carcinoembryonic Antigen; Cell Survival; Colonic Neoplasms; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Polyethylene glycol induces apoptosis in HT-29 cells: potential mechanism for chemoprevention of colon cancer.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Division; Cell Separation; Cell Survival; Colonic Neoplasms; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; HT29 Cells; Humans; Intracellular Signaling Peptides and Proteins; Polyethylene Glycols; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Role of thromboxane in retinal microvascular degeneration in oxygen-induced retinopathy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Capillaries; Cell Survival; Cells, Cultured; DNA Fragmentation; L-Lactate Dehydrogenase; Oxygen; Rats; Rats, Sprague-Dawley; Retinal Diseases; Retinal Vessels; Tetrazolium Salts; Thiazoles; Thromboxane A2 | 2001 |
Effects of proteasome inhibitor PSI on neoplastic and non-transformed cell lines.
Topics: Algorithms; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Genes, ras; Humans; Mice; Multienzyme Complexes; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Evaluation of hepatic subcellular fractions for Alamar blue and MTT reductase activity.
Topics: Animals; Coloring Agents; Cytosol; Female; Fluorescence; Formazans; In Vitro Techniques; Microsomes, Liver; Mitochondria; Oxazines; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrophotometry; Spectrum Analysis; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2001 |
Induction of apoptosis by the marine sponge (Mycale) metabolites, mycalamide A and pateamine.
Topics: Animals; Annexin A5; Apoptosis; Cell Survival; Coloring Agents; Cycloheximide; Cytarabine; DNA; DNA Damage; Electrophoresis, Agar Gel; Enzyme Inhibitors; Epoxy Compounds; Flow Cytometry; Inhibitory Concentration 50; Macrolides; Models, Chemical; Porifera; Protein Synthesis Inhibitors; Puromycin; Pyrans; Tetrazolium Salts; Thiazoles; Trypan Blue | 2001 |
Prodigiosin-induced apoptosis in human colon cancer cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Apoptosis; Benzimidazoles; Caspases; Cell Survival; Colonic Neoplasms; DNA; Drug Screening Assays, Antitumor; Enzyme Activation; Fluorescent Dyes; Humans; Mice; Prodigiosin; Serratia marcescens; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Calcipotriol inhibits autocrine phosphorylation of EGF receptor in a calcium-dependent manner, a possible mechanism for its inhibition of cell proliferation and stimulation of cell differentiation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents; Apoptosis; Autocrine Communication; Blotting, Western; Bromodeoxyuridine; Calcitriol; Calcium; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cell Line; ErbB Receptors; Fluorescent Dyes; Humans; Keratinocytes; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Precursors; Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetrazolium Salts; Thiazoles | 2001 |
Huperzine A and donepezil protect rat pheochromocytoma cells against oxygen-glucose deprivation.
Topics: Alkaloids; Alzheimer Disease; Animals; Cell Size; Cell Survival; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Glucose; Hypoxia-Ischemia, Brain; Indans; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Piperidines; Rats; Sesquiterpenes; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2001 |
Neoadjuvant chemotherapy in inoperable, locally advanced, and inflammatory breast carcinoma: a pilot study of MTT assay in vitro and outcome analysis of 10 patients.
Topics: Adenocarcinoma; Adult; Breast Neoplasms; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Middle Aged; Neoplasm Staging; Pilot Projects; Tetrazolium Salts; Thiazoles | 2001 |
Gene transfer of p53 to arthritic joints stimulates synovial apoptosis and inhibits inflammation.
Topics: Adenoviridae; Animals; Apoptosis; Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Fibroblasts; Genetic Vectors; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Interleukin-1; Knee Joint; Lac Operon; Proteoglycans; Rabbits; Synovial Membrane; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2001 |
Trans-resveratrol, a grapevine-derived polyphenol, blocks hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Flavonoids; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Phenols; Phosphorylation; Poly(ADP-ribose) Polymerases; Polymers; Polyphenols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Resveratrol; RNA, Messenger; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Genetic Vectors; Head and Neck Neoplasms; Humans; Interleukin-1; Interleukin-8; Mutation; NF-kappa B; Plasmids; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress.
Topics: Aldehydes; Amyloid beta-Peptides; Blotting, Western; Cell Survival; Drug Resistance, Neoplasm; Ferrous Compounds; Gene Expression; Glutathione; Glutathione Transferase; Humans; Hydrogen Peroxide; Isoenzymes; L-Lactate Dehydrogenase; Neuroblastoma; Oxidative Stress; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2001 |
On the transformation behaviour, mechanical properties and biocompatibility of two niti-based shape memory alloys: NiTi42 and NiTi42Cu7.
Topics: Alloys; Biocompatible Materials; Cells, Cultured; Cobalt; Coloring Agents; Epithelial Cells; Gingiva; Immunohistochemistry; Materials Testing; Microscopy, Electron, Scanning; Nickel; Stress, Mechanical; Temperature; Tetrazolium Salts; Thermodynamics; Thiazoles; Titanium | 2001 |
Chloroaluminum phthalocyanine tetrasulfonate delivered via acid-labile diplasmenylcholine-folate liposomes: intracellular localization and synergistic phototoxicity.
Topics: Aluminum; Biological Transport; Cell Survival; Dermatitis, Phototoxic; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Indoles; KB Cells; Liposomes; Luciferases; Microscopy, Confocal; Molecular Structure; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Plasmalogens; Tetrazolium Salts; Thiazoles | 2001 |
Organotins disrupt components of glutamate homeostasis in rat astrocyte cultures.
Topics: Animals; Astrocytes; Cells, Cultured; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Homeostasis; L-Lactate Dehydrogenase; Organotin Compounds; Pregnancy; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2001 |
The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Apoptosis; Binding Sites; Blotting, Western; Caspase 3; Caspases; Cell Division; Cell Line; Cell Movement; Cell Survival; DNA; DNA Damage; DNA Fragmentation; DNA Repair; Dogs; Doxorubicin; Enzyme Inhibitors; Epithelial Cells; Genetic Vectors; GRB2 Adaptor Protein; Hepatocyte Growth Factor; Humans; Models, Biological; Mutation; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Wortmannin | 2001 |
Suppression of matrix metalloproteinase-2 and -9 mediated invasiveness by a novel matrix metalloproteinase inhibitor, BE16627B.
Topics: Antineoplastic Agents; Collagen Type IV; Coloring Agents; Dipeptides; Glioma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Protease Inhibitors; Succinates; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
4-Acetyl-12,13-epoxyl-9-trichothecene-3,15-diol isolated from the fruiting bodies of Isariajaponica Yasuda induces apoptosis of human leukemia cells (HL-60).
Topics: Apoptosis; Coloring Agents; DNA Fragmentation; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; HL-60 Cells; Humans; Hypocreales; Indoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophils; Tetrazolium Salts; Thiazoles; Trichothecenes | 2001 |
The effect of methyl methanesulfonate (MMS)-induced excision repair on p53-dependent apoptosis in human lymphoid cells.
Topics: Alkylation; Apoptosis; Cell Line; Cell Survival; DNA Repair; Enzyme-Linked Immunosorbent Assay; Genes, p53; Humans; Kinetics; Lymphocytes; Methyl Methanesulfonate; Mutagens; Tetrazolium Salts; Thiazoles | 2001 |
Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor.
Topics: Aldehyde Reductase; Antimetabolites; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cold Temperature; Enzyme Inhibitors; Epithelial Cells; Fluorescein; Glycine; Humans; Indicators and Reagents; Pigment Epithelium of Eye; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Tetrazolium Salts; Thiazoles | 2001 |
Follicular stage-dependent tumor necrosis factor alpha-induced hen granulosa cell integrin production and survival in the presence of transforming growth factor alpha in vitro.
Topics: Acridine Orange; Animals; Blotting, Western; Cell Adhesion; Cell Survival; Cells, Cultured; Chickens; Coloring Agents; DNA Fragmentation; Drug Interactions; Ethidium; Female; Fibronectins; Granulosa Cells; Integrins; Ovarian Follicle; Tetrazolium Salts; Thiazoles; Thymidine; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 2001 |
Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons.
Topics: Animals; Cells, Cultured; Coloring Agents; Convulsants; Corpus Striatum; DNA Fragmentation; Electron Transport Complex II; Fetus; Manganese; Manganese Poisoning; Membrane Potentials; Mice; Microtubule-Associated Proteins; Mitochondria; Multienzyme Complexes; Nerve Degeneration; Neurons; Neurotoxins; Nitro Compounds; Oxidoreductases; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2001 |
Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and -negative nasopharyngeal carcinoma.
Topics: Adenoviridae; Antineoplastic Agents; beta-Galactosidase; Blotting, Western; Cell Survival; Cisplatin; Combined Modality Therapy; Epstein-Barr Virus Infections; Gene Expression; Genetic Therapy; Genetic Vectors; Herpesvirus 4, Human; Humans; Nasopharyngeal Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Protein p53 | 2001 |
Effects of advanced glycation end products on the proliferation and fibronectin production of smooth muscle cells.
Topics: Animals; Antibodies; Cattle; Cell Division; Cells, Cultured; Fibronectins; Glycation End Products, Advanced; Muscle, Smooth, Vascular; Serum Albumin, Bovine; Swine; Tetrazolium Salts; Thiazoles; Thymidine; Transforming Growth Factor beta | 2000 |
Cytotoxicity testing with three-dimensional cultures of transfected pulp-derived cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Cattle; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media; Dental Pulp; Dentin; Diffusion Chambers, Culture; Fibroblasts; Humans; Perfusion; Phenol; Root Canal Filling Materials; Sensitivity and Specificity; Skin; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors; Tolonium Chloride; Transfection; Zinc Oxide-Eugenol Cement; Zinc Phosphate Cement | 2001 |
Dentin barrier test with transfected bovine pulp-derived cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Biocompatible Materials; Cattle; Cell Culture Techniques; Cell Division; Cell Survival; Cermet Cements; Clone Cells; Coloring Agents; Dental Cements; Dental Pulp; Dentin; Fibroblasts; Glass Ionomer Cements; Humans; Microscopy, Electron, Scanning; Resin Cements; Silicone Elastomers; Skin; Spectrophotometry; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zinc Oxide-Eugenol Cement; Zinc Phosphate Cement | 2001 |
PPAR-gamma ligands inhibit growth of human esophageal adenocarcinoma cells through induction of apoptosis, cell cycle arrest and reduction of ornithine decarboxylase activity.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Chromans; DNA Primers; Esophageal Neoplasms; Flow Cytometry; Humans; Immunologic Factors; Ligands; Ornithine Decarboxylase; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Thymidine; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2001 |
Cathepsin L antisense oligonucleotides in a human osteosarcoma cell line: effects on the invasive phenotype.
Topics: Basement Membrane; Blotting, Northern; Cathepsin B; Cathepsin F; Cathepsin K; Cathepsin L; Cathepsins; Cell Adhesion; Cell Division; Cell Movement; Collagen; Cysteine Endopeptidases; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Humans; Laminin; Neoplasm Invasiveness; Oligonucleotides, Antisense; Osteosarcoma; Phenotype; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2001 |
Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression.
Topics: Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutamate-Cysteine Ligase; Glutathione; Humans; RNA, Catalytic; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2'-O-(2-methoxy)ethyl chemistry.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Northern; Clusterin; Electrophoresis, Capillary; Glycoproteins; Half-Life; Humans; Male; Mice; Molecular Chaperones; Neoplasm Proteins; Oligonucleotides, Antisense; Paclitaxel; Prostatic Neoplasms; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Metal-induced hormesis requires cPKC-dependent glucose transport and lowered respiration.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Culture Techniques; Cell Respiration; Coloring Agents; Dose-Response Relationship, Drug; Glucose; Metals, Heavy; Mice; Mitochondria; Oxidative Stress; Oxygen Consumption; Protein Kinase C; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2001 |
Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF10A human breast epithelial cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast; Caspase 3; Caspases; Curcumin; DNA Fragmentation; Enzyme Activation; Epithelial Cells; Female; Gene Expression Regulation; Genes, bcl-2; Genes, ras; Humans; Immunoblotting; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Role of kainate receptor activation and desensitization on the [Ca(2+)](i) changes in cultured rat hippocampal neurons.
Topics: Animals; Benzodiazepines; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Chelating Agents; Concanavalin A; Excitatory Amino Acid Antagonists; Fetus; Fura-2; GluK3 Kainate Receptor; Glutamates; Hippocampus; Immunohistochemistry; Kainic Acid; Microscopy, Confocal; Microtubule-Associated Proteins; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Tetrazolium Salts; Thiazoles | 2001 |
The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.
Topics: Apoptosis; Blotting, Western; Cell Adhesion; Cell Division; Cell Line; Cell Survival; Chemokine CXCL12; Chemokines, CXC; Coloring Agents; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hematopoietic Stem Cells; HL-60 Cells; Humans; Integrins; Jurkat Cells; Lymphokines; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Cytotoxic evaluation of root canal filling materials on primary human oral fibroblast cultures and a permanent hamster cell line.
Topics: Analysis of Variance; Animals; Cell Line; Colorimetry; Coloring Agents; Cricetinae; Cricetulus; Drug Combinations; Epoxy Resins; Eugenol; Fibroblasts; Formaldehyde; Gingiva; Humans; Mouth Mucosa; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Zinc Oxide; Zinc Oxide-Eugenol Cement | 2001 |
Reduction in cholesterol and sialic acid content protects cells from the toxic effects of beta-amyloid peptides.
Topics: Amyloid beta-Peptides; Animals; Cholesterol; Cytoprotection; Gangliosides; GTP Phosphohydrolases; Humans; N-Acetylneuraminic Acid; Oxidation-Reduction; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Therapeutic effects of viral vector-mediated antiangiogenic gene transfer in malignant ascites.
Topics: Adenoviridae; Angiostatins; Animals; Apoptosis; Ascites; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Cell Movement; Cells, Cultured; Collagen; Coloring Agents; Down-Regulation; Endostatins; Endothelial Growth Factors; Endothelium; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Gene Transfer Techniques; Genetic Vectors; Humans; Immunohistochemistry; Lymphokines; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Peptide Fragments; Plasmids; Plasminogen; Platelet Factor 4; Recombinant Fusion Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
alpha-Synuclein affects the MAPK pathway and accelerates cell death.
Topics: 14-3-3 Proteins; alpha-Synuclein; Amino Acid Sequence; Apoptosis; Blotting, Northern; Butadienes; Cell Death; Cell Line; Cell Survival; Coloring Agents; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Library; Glutathione Transferase; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; MAP Kinase Signaling System; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Nitriles; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Synucleins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine 3-Monooxygenase | 2001 |
Sensitivity of mitochondrial respiration to different inhibitors in Venturia inaequalis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ascomycota; Biological Assay; Cytochrome b Group; Fungicides, Industrial; Mitochondria; Mycelium; NAD; Oxygen Consumption; RNA, Messenger; Spores; Tetrazolium Salts; Thiazoles | 2001 |
[Studies on inhibiting activities of five antitumour drugs to human cancer cell in vitro with MTT assay].
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Renal Cell; Cell Division; Chromans; Coloring Agents; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Immunohistochemistry; Immunologic Factors; Kidney Neoplasms; Ligands; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Cells, Cultured; Up-Regulation | 2001 |
Simplified serum- and steroid-free culture conditions for high-throughput viability analysis of primary cultures of cerebellar granule neurons.
Topics: Animals; Animals, Newborn; Cell Culture Techniques; Cell Survival; Cells, Cultured; Cerebellar Cortex; Coloring Agents; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; L-Lactate Dehydrogenase; Male; Neurons; Neurophysiology; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Steroids; Tetrazolium Salts; Thiazoles | 2001 |
Endocytosis in rat cultured astrocytes is inhibited by unconjugated bilirubin.
Topics: Animals; Astrocytes; Bilirubin; Cells, Cultured; Endocytosis; Ferritins; Glial Fibrillary Acidic Protein; Immunohistochemistry; Oxidation-Reduction; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Tubulin | 2001 |
Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Inducing Factor; Breast Neoplasms; Caspase 3; Caspases; Coloring Agents; Cysteine Proteinase Inhibitors; Cytochrome c Group; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Flavoproteins; Hepatocyte Growth Factor; Humans; Membrane Glycoproteins; Membrane Potentials; Membrane Proteins; Mitochondria; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Up-Regulation | 2001 |
Toxic effects of mitomycin-C on cultured ciliary process cells and trabecular meshwork cells.
Topics: Animals; Antimetabolites; Calcium; Cells, Cultured; Ciliary Body; Cyclic AMP; DNA Fragmentation; DNA Replication; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Lethal Dose 50; Mitomycin; Rabbits; Tetrazolium Salts; Thiazoles; Thymidine; Trabecular Meshwork | 2001 |
Effect of Actinobacillus actinomycetemcomitans protease on the proliferation of gingival epithelial cells.
Topics: Aggregatibacter actinomycetemcomitans; Bacterial Proteins; Bromodeoxyuridine; Cell Division; Cells, Cultured; Colorimetry; Coloring Agents; Cysteine Endopeptidases; DNA; Dose-Response Relationship, Drug; Epithelial Cells; Fibronectins; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gingiva; Humans; Statistics as Topic; Tetrazolium Salts; Thiazoles; Trypsin; Virulence | 2001 |
Synthesis of the L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine.
Topics: Anti-HIV Agents; Cell Line; Coloring Agents; Deoxycytidine; HIV-1; Hydrogen-Ion Concentration; Indicators and Reagents; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Fast Atom Bombardment; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2001 |
Effect of melatonin on cell growth, metabolic activity, and cell cycle distribution.
Topics: Adjuvants, Immunologic; Antioxidants; Cell Division; Cell Line, Transformed; Cell Survival; Flow Cytometry; Humans; Interphase; Kidney; Melatonin; Pyrrolidines; Tetrazolium Salts; Thiazoles; Thiocarbamates | 2001 |
Protection against chemotherapy-induced cytotoxicity by cyclin-dependent kinase inhibitors (CKI) in CKI-responsive cells compared with CKI-unresponsive cells.
Topics: Cell Cycle Proteins; Cell Division; Cisplatin; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA Mutational Analysis; DNA, Complementary; Dose-Response Relationship, Drug; Ecdysone; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Mutation; Paclitaxel; Phosphorylation; Promoter Regions, Genetic; Retinoblastoma Protein; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Structurally related immunological effects of triterpenoid saponins.
Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Female; Immunity, Cellular; In Vitro Techniques; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred DBA; Phagocytosis; Plants, Medicinal; Saponins; Spleen; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triterpenes | 2001 |
Exogenous expression of p21(WAF1/CIP1) exerts cell growth inhibition and enhances sensitivity to cisplatin in hepatoma cells.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Genes, p53; Humans; Liver Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2001 |
[Compared study on Fura-2/AM assay and MTT assay for screening multidrug resistant modulators].
Topics: Bepridil; Breast Neoplasms; Calcium Channel Blockers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fura-2; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 1997 |
Alpha-lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Assay; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Coloring Agents; Dose-Response Relationship, Drug; Drug Interactions; Fetus; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Thioctic Acid | 2001 |
[Cytotoxicity of the strontium-substituted hydroxyapatite evaluated by MTT colorimetry].
Topics: Animals; Colorimetry; Cytotoxicity, Immunologic; Hydroxyapatites; In Vitro Techniques; Mice; Strontium; Tetrazolium Salts; Thiazoles | 2001 |
Macrophage-oriented cytotoxic activity of novel triterpene saponins extracted from roots of Securidaca inappendiculata.
Topics: Animals; Cell Death; Cells, Cultured; In Situ Nick-End Labeling; Indicators and Reagents; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred C3H; Plant Extracts; Plant Roots; Plants, Medicinal; Polygalaceae; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes | 2001 |
Preparation, physicochemical characterization and pharmacological study of novel ruthenium(III) complexes with imidazole and benzimidazole derivatives.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Burkitt Lymphoma; Cell Survival; Chemical Phenomena; Chemistry, Physical; Drug Screening Assays, Antitumor; Humans; Imidazoles; Indicators and Reagents; Lethal Dose 50; Male; Mice; Ruthenium; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Cytotoxicity of synthetic estrogen and related compounds in various tumor-derived cells.
Topics: 3T3 Cells; Animals; Antineoplastic Agents, Hormonal; Cell Survival; Cell Transformation, Neoplastic; Diethylstilbestrol; Drug Screening Assays, Antitumor; Estradiol Congeners; Humans; KB Cells; Leukemia L1210; Mice; Oncogenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Cell death associated with genetic prodrug activation therapy of colorectal cancer.
Topics: Adenoviridae; Animals; Cell Cycle; Cell Death; Colorectal Neoplasms; Disease Models, Animal; DNA Fragmentation; Flow Cytometry; Ganciclovir; Genetic Therapy; Genetic Vectors; Humans; Mice; Neoplasm Transplantation; Phosphorylation; Prodrugs; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured | 2001 |
Chromium (VI)-induced oxidative stress, apoptotic cell death and modulation of p53 tumor suppressor gene.
Topics: Animals; Apoptosis; Carcinogens; Cell Line; Chromium; Cytochrome c Group; DNA Fragmentation; Female; Flow Cytometry; Gene Expression Regulation; Humans; Hydroxyl Radical; K562 Cells; Leukemia, Myeloid; Lipid Peroxidation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Oxidation-Reduction; Oxidative Stress; Superoxides; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2001 |
Abnormal development of hypoxanthine-guanine phosphoribosyltransferase-deficient CNS neuroblastoma.
Topics: Cell Count; Cell Differentiation; Cell Division; Cell Size; Central Nervous System; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Neurites; Neuroblastoma; Neurons; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Trypan blue uptake by chinese hamster ovary cultured epithelial cells: a cellular model to study Escherichia coli STb enterotoxin.
Topics: Amino Acid Sequence; Animals; Bacterial Toxins; Cell Line; Cell Survival; CHO Cells; Cricetinae; Enterotoxins; Escherichia coli Proteins; In Vitro Techniques; Indicators and Reagents; Jejunum; Molecular Sequence Data; Mutation; Rats; Tetrazolium Salts; Thiazoles; Trypan Blue | 2002 |
Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties.
Topics: Aldehyde Reductase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Cinnamomum; Gas Chromatography-Mass Spectrometry; Glutathione Transferase; Humans; Lipid Peroxidation; Liver; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Oils, Volatile; Plant Epidermis; Plant Stems; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Xanthine Oxidase | 2001 |
Ethanol-induced oxidative stress in rat astrocytes: role of HSP70.
Topics: Animals; Astrocytes; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Coloring Agents; Comet Assay; Ethanol; HSP70 Heat-Shock Proteins; Immunoblotting; L-Lactate Dehydrogenase; Malondialdehyde; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 2001 |
Chemosensitivity testing predicts survival in ovarian cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cell Survival; Coloring Agents; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Middle Aged; Ovarian Neoplasms; Predictive Value of Tests; Retrospective Studies; Survival Rate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Adaptation of an [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay to evaluate the cytotoxicity of the extracellular products of micro-organisms pathogenic to fish.
Topics: Animals; Bacteria; Bacterial Proteins; Cell Line; Cell Survival; Colorimetry; Sea Bream; Tetrazolium Salts; Thiazoles; Trypan Blue | 2001 |
In vitro cytotoxicity of the organophosphorus pesticide parathion to FG-9307 cells.
Topics: Animals; Cell Extracts; Cell Line; Cell Nucleus; Culture Media, Conditioned; Cytoplasm; Dose-Response Relationship, Drug; Flounder; Gills; Insecticides; Neutral Red; Parathion; Proteins; Tetrazolium Salts; Thiazoles | 2001 |
Melatonin protects SHSY5Y neuroblastoma cells from cobalt-induced oxidative stress, neurotoxicity and increased beta-amyloid secretion.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cobalt; Glutathione; Humans; Melatonin; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Increased cytotoxicity and stability of Lipiodol-pirarubicin emulsion compared to classical doxorubicin-Lipiodol: potential advantage for chemoembolization of unresectable hepatocellular carcinoma.
Topics: Amiodarone; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chromatography, High Pressure Liquid; Doxorubicin; Drug Resistance, Multiple; Drug Stability; Emulsions; Enzyme Inhibitors; Humans; Iodized Oil; Liver Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Synergy, pharmacodynamics, and time-sequenced ultrastructural changes of the interaction between nikkomycin Z and the echinocandin FK463 against Aspergillus fumigatus.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Aspergillus fumigatus; Drug Synergism; Echinocandins; Kinetics; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Microscopy, Electron; Peptides, Cyclic; Tetrazolium Salts; Thiazoles | 2001 |
Tailoring of new polymeric biomaterials for the repair of medium-sized corneal perforations.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Calorimetry, Differential Scanning; Cornea; Corneal Injuries; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Methacrylates; Mice; Polymers; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thermogravimetry; Thiazoles | 2000 |
Involvement of tetrahydrobiopterin in trophic effect of erythropoietin on PC12 cells.
Topics: Animals; Biopterins; Cell Line; Cell Survival; Coloring Agents; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythropoietin; Hypoxanthines; PC12 Cells; Protein Binding; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2001 |
Triphenyltin acetate-induced cytotoxicity and CD4(+) and CD8(+) depletion in mouse thymocyte primary cultures.
Topics: Animals; CD4 Antigens; CD8 Antigens; Cell Division; Cell Survival; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Drug; Female; Flow Cytometry; Fungicides, Industrial; Mice; Mice, Inbred BALB C; Neutral Red; Organotin Compounds; Tetrazolium Salts; Thiazoles; Thymus Gland; Trypan Blue | 2001 |
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy.
Topics: Blotting, Western; Cell Cycle; Cell Line; Cell Nucleus; Cloning, Molecular; Coloring Agents; Cytoplasm; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Reporter; Glioblastoma; Humans; Microscopy, Confocal; Mutation; Neoplasms; Nuclear Proteins; Phosphoric Monoester Hydrolases; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; PTEN Phosphohydrolase; Retroviridae; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2002 |
Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Line; Cell Survival; Cloning, Molecular; Coloring Agents; DNA Fragmentation; DNA, Complementary; Electrophoresis, Agar Gel; Genes, Dominant; Glycation End Products, Advanced; HMGB1 Protein; Humans; Immunohistochemistry; Mice; Neuroblastoma; Neurons; Oligonucleotides, Antisense; Plasmids; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2002 |
Antitumor action of the PKC activator gnidimacrin through cdk2 inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; CDC2-CDC28 Kinases; cdc25 Phosphatases; Cell Cycle; Coloring Agents; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Diterpenes; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; K562 Cells; Mice; Models, Biological; Models, Chemical; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Regulation of u-PA gene expression in human prostate cancer.
Topics: Blotting, Northern; Blotting, Western; Cell Division; Chloramphenicol O-Acetyltransferase; Coloring Agents; Down-Regulation; Flutamide; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Male; MAP Kinase Signaling System; Mutation; Promoter Regions, Genetic; Prostatic Neoplasms; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
Microglial cells protect cerebellar granule neurons from apoptosis: evidence for reciprocal signaling.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Communication; Cell Count; Cell Survival; Cells, Cultured; Cerebellar Cortex; Coculture Techniques; Culture Media, Conditioned; Microglia; Neurons; Potassium Deficiency; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2001 |
gamma-Glutamyltranspeptidase-dependent metabolism of 4-hydroxynonenal-glutathione conjugate.
Topics: Aldehydes; Animals; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Cricetinae; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; gamma-Glutamyltransferase; Glutathione; Humans; Kinetics; Mass Spectrometry; Models, Chemical; Protein Binding; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Distinct effects of tea catechins on 6-hydroxydopamine-induced apoptosis in PC12 cells.
Topics: Adrenergic Agents; Animals; Apoptosis; Beverages; Catechin; Cell Nucleus; Cell Survival; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flavonoids; Flow Cytometry; Models, Chemical; Oxidopamine; PC12 Cells; Phenols; Polymers; Rats; Tetrazolium Salts; Thiazoles | 2002 |
Cadmium induces alpha(1)collagen (I) and metallothionein II gene and alters the antioxidant system in rat hepatic stellate cells.
Topics: Animals; Antioxidants; Blotting, Northern; Cadmium; Calcium; Catalase; Cell Line; Chemical and Drug Induced Liver Injury; Collagen Type I; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Lipid Peroxidation; Liver; Metallothionein; Neutral Red; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2002 |
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways.
Topics: Amino Acids; Anilides; Blotting, Northern; Colforsin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Immunoblotting; Interleukin-6; Janus Kinase 1; Luciferases; Male; MAP Kinase Signaling System; Models, Biological; Nitriles; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tosyl Compounds; Trans-Activators; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Histopathologic features of retinoblastoma and its relation with in vitro drug resistance measured by means of the MTT assay.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Size; Cytarabine; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Retinoblastoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Effects of nimesulide and its metabolites or manufacturing intermediates on the viability and growth of the human hepatoma HepG2 cell line.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cyclooxygenase Inhibitors; Hepatocytes; Humans; Mitochondria, Liver; Sulfonamides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Differential effects of non-genotoxic carcinogens and proliferating agents on cell growth, survival and apoptosis in hepatic cells in vitro.
Topics: Apoptosis; Carcinogens; Cell Count; Cell Division; Chlorobenzenes; Diethylhexyl Phthalate; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Hepatocytes; Human Growth Hormone; Humans; Hydroxyacetylaminofluorene; Mitogens; Nickel; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 2001 |
Activation of matrix metalloproteinase-2 by a novel oral spirochetal species Treponema lecithinolyticum.
Topics: Animals; Bacterial Outer Membrane Proteins; Cattle; Cells, Cultured; Collagen Type IV; Coloring Agents; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibroblasts; Gingiva; Humans; Immunoblotting; Matrix Metalloproteinase 2; Periodontal Ligament; Periodontitis; Tetrazolium Salts; Thiazoles; Time Factors; Treponema | 2001 |
[Examination of in vitro chemosensitivity test using methylthiazole tetrazolium bromide chemosensitivity (MTT) test with combined drugs in hepatic arterial infusion chemotherapy for carcinoma of the liver].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Coloring Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Mice; Mice, Nude; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 2001 |
Gender difference in cytoprotection induced by estrogen on female and male bovine aortic endothelial cells.
Topics: Animals; Antioxidants; Aorta, Thoracic; Cattle; Cell Survival; Endothelium, Vascular; Estradiol; Estrogens; Female; Flow Cytometry; Herbicides; Hot Temperature; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Oxidants; Paraquat; Reactive Oxygen Species; Sex Characteristics; Tetrazolium Salts; Thiazoles | 2001 |
The role of the MAP-kinase superfamily in beta-amyloid toxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blotting, Western; Coloring Agents; Dose-Response Relationship, Drug; Hydrogen Peroxide; In Vitro Techniques; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules.
Topics: 12E7 Antigen; Adaptor Proteins, Signal Transducing; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Apoptosis; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Line; Cell Nucleus; Co-Repressor Proteins; Cross-Linking Reagents; DNA, Complementary; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Hematopoietic Stem Cells; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Kinetics; Leukocyte Common Antigens; Leukosialin; Molecular Chaperones; NF-kappa B; Nuclear Proteins; Oligonucleotides; Plasmids; Protein Binding; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Two-Hybrid System Techniques | 2002 |
IL-10 promotes survival of microglia without activating Akt.
Topics: Animals; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; DNA-Binding Proteins; Enzyme Activation; Insulin-Like Growth Factor I; Interleukin-10; Mice; Microglia; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Interleukin; Receptors, Interleukin-10; Serine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Trans-Activators; Tyrosine | 2002 |
Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Ear, External; Edema; Female; Foot; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Inflammation; Leukotriene B4; Leukotrienes; Mice; Neutrophils; Oleanolic Acid; Oxidation-Reduction; Peroxidase; Pistacia; Rats; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triterpenes | 2001 |
Inhibitors of fibril formation and cytotoxicity of beta-amyloid peptide composed of KLVFF recognition element and flexible hydrophilic disrupting element.
Topics: Amyloid beta-Peptides; Benzothiazoles; Cell Division; Cell Survival; Coloring Agents; Congo Red; Enzyme Inhibitors; Fluorescent Dyes; Humans; Models, Chemical; Peptide Fragments; Peptides; Pigments, Biological; Protein Binding; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2002 |
Phospholipase A2-mediated Ca2+ influx by 2,2',4,6-tetrachlorobiphenyl in PC12 cells.
Topics: Animals; Apoptosis; Calcium; Cell Nucleus; Coloring Agents; DNA Fragmentation; Neurons; Neurotoxins; PC12 Cells; Phospholipases A; Phospholipases A2; Polychlorinated Biphenyls; Rats; Tetrazolium Salts; Thiazoles | 2002 |
HSP70 overexpression increases resistance of V79 cells to cytotoxicity of airborne pollutants, but does not protect the mitotic spindle against damage caused by airborne toxins.
Topics: Air Pollutants, Occupational; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cricetinae; Fibroblasts; HSP70 Heat-Shock Proteins; Immunohistochemistry; Plasmids; Spindle Apparatus; Tetrazolium Salts; Thiazoles; Transfection | 2002 |
Aluminum toxicity is associated with mitochondrial dysfunction and the production of reactive oxygen species in plant cells.
Topics: Adenosine Triphosphate; Aluminum; Antioxidants; Butylated Hydroxyanisole; Mitochondria; Nicotiana; Pisum sativum; Plant Cells; Plant Development; Plant Roots; Reactive Oxygen Species; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2002 |
Mortality and morphological changes in Giardia duodenalis induced by exposure to ethanolic extracts of Justicia spicigera.
Topics: Animals; Culture Media; Ethanol; Giardia; Microscopy, Electron; Plant Extracts; Plants, Medicinal; Solvents; Tetrazolium Salts; Thiazoles | 2001 |
Morphological behavior of osteoblast-like cells on surface-modified titanium in vitro.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cell Differentiation; Cell Division; Collagen Type I; Coloring Agents; Durapatite; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Ions; Mice; Microscopy, Electron, Scanning; Osteoblasts; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2002 |
Effect of surface treatment on the biocompatibility of microbial polyhydroxyalkanoates.
Topics: Animals; Biocompatible Materials; Carboxylic Acids; Cell Division; Cell Line; Cell Survival; Coloring Agents; Fibroblasts; Hydrogen-Ion Concentration; Hydroxybutyrates; Lipase; Materials Testing; Mice; Microscopy, Electron, Scanning; Polymers; Sodium Hydroxide; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Depressant effect of ambroxol on stimulated functional responses and cell death in rat alveolar macrophages exposed to silica in vitro.
Topics: Acid Phosphatase; Ambroxol; Animals; Calcium; Caspase 3; Caspases; Cell Death; Cytoplasmic Granules; Expectorants; Hydrogen Peroxide; In Vitro Techniques; Macrophage Activation; Macrophages, Alveolar; Muramidase; Nitrites; Oxidants; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Respiratory Burst; Silicon Dioxide; Superoxides; Tetrazolium Salts; Thiazoles | 2002 |
Cytotoxic effects of cleansing solutions recommended for chemical lavage of pulp exposures.
Topics: Analysis of Variance; Animals; Anti-Infective Agents, Local; Calcium Hydroxide; Cell Adhesion; Cell Count; Cell Line; Coloring Agents; Culture Media; Dental Pulp Exposure; Dentin-Bonding Agents; Hydrogen Peroxide; Mice; Microscopy, Electron, Scanning; Mitochondria; Odontoblasts; Oxidants; Resin Cements; Sodium Chloride; Sodium Hypochlorite; Statistics as Topic; Tetrazolium Salts; Therapeutic Irrigation; Thiazoles | 2001 |
Effect of toothbrushing on the toxicity of casting alloys.
Topics: 3T3 Cells; Analysis of Variance; Animals; Beryllium; Biocompatible Materials; Cell Survival; Cells, Cultured; Chromium Alloys; Coloring Agents; Copper; Dental Alloys; Dental Casting Investment; Gallium; Gold Alloys; Hydrogen-Ion Concentration; Materials Testing; Mice; Palladium; Platinum; Sodium Chloride; Sodium Lactate; Statistics as Topic; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Toothbrushing; Toothpastes | 2002 |
[Evaluation on the cytotoxicity of Gallium alloy by MTT-assay].
Topics: Alloys; Animals; Cell Division; Fibroblasts; Gallium; Mice; Tetrazolium Salts; Thiazoles | 2001 |
Subacute cytotoxicity testing with cultured human lung cells.
Topics: Animal Testing Alternatives; Animals; Cell Division; Dose-Response Relationship, Drug; Fibroblasts; Humans; Lethal Dose 50; Lung; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xenobiotics | 2002 |
Photo-induced cytotoxicity of malonic acid [C(60)]fullerene derivatives and its mechanism.
Topics: Carbon; Cell Cycle; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Flow Cytometry; Fullerenes; HeLa Cells; Humans; Light; Malonates; Mannitol; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2002 |
Formaldehyde cytotoxicity in three human cell types assessed in three different assays.
Topics: Bromodeoxyuridine; Dental Pulp; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Formaldehyde; HeLa Cells; Humans; Mouth Mucosa; Neutral Red; Reproducibility of Results; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 2002 |
Effect of diquat on the antioxidant system and cell growth in human neuroblastoma cells.
Topics: Antioxidants; Brain Neoplasms; Cell Division; Cell Survival; Diquat; Glutathione; Herbicides; Humans; Indicators and Reagents; Mitochondria; Neoplasm Proteins; Neuroblastoma; Neurons; Oxidation-Reduction; Oxidative Stress; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin.
Topics: Animals; Cattle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Humans; Linoleic Acid; Mitochondria; Oleic Acids; Oxygen; Oxygen Consumption; Serum Albumin, Bovine; Spodoptera; Tetrazolium Salts; Thiazoles | 2002 |
Antimycobacterial activity of 4'-bromo-[1,1'-biphenyl]-4-yl 4-x-phenylmethanone derivatives, and their acute toxicity and cytotoxicity.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Biphenyl Compounds; CHO Cells; Coloring Agents; Cricetinae; Drug Screening Assays, Antitumor; Escherichia coli; Fibroblasts; Humans; Microbial Sensitivity Tests; Mycobacterium; Neutral Red; Nucleic Acids; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons.
Topics: Amino Acids; Animals; Astrocytes; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Mitochondria; Neurons; Osmolar Concentration; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Substrate Specificity; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Striatal dopaminergic pathways as a target for the insecticides permethrin and chlorpyrifos.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chlorpyrifos; Coloring Agents; Dopamine; In Vitro Techniques; Insecticides; Kinetics; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neural Pathways; Permethrin; Synaptosomes; Tetrazolium Salts; Thiazoles | 2001 |
Effects of DMAEMA and 4-methoxyphenol on gingival fibroblast growth, metabolism, and response to interleukin-1.
Topics: Anisoles; Antioxidants; Cell Division; Cells, Cultured; Fibroblasts; Gentian Violet; Gingiva; Humans; Interleukin-1; Methacrylates; Mitochondria; Reducing Agents; Tetrazolium Salts; Thiazoles | 2002 |
Smooth muscle cell adhesion on crosslinked hyaluronan gels.
Topics: Animals; Animals, Newborn; Aorta, Thoracic; Biocompatible Materials; Cell Adhesion; Cell Separation; Collagen; Coloring Agents; Cross-Linking Reagents; DNA; Fibronectins; Gels; Hyaluronic Acid; Immunohistochemistry; Muscle, Smooth, Vascular; Rats; Sulfones; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
Tartary buckwheat flavonoid activates caspase 3 and induces HL-60 cell apoptosis.
Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; Cell Division; Cells, Cultured; DNA; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme Activators; Fagopyrum; Flavonoids; HL-60 Cells; Humans; Tetrazolium Salts; Thiazoles | 2001 |
Long-term cytotoxicity of resin-based dental restorative materials.
Topics: 3T3 Cells; Analysis of Variance; Animals; Biocompatible Materials; Cariostatic Agents; Colorimetry; Coloring Agents; Composite Resins; Culture Media; Dental Materials; Dental Restoration, Permanent; Materials Testing; Methacrylates; Mice; Mice, Inbred BALB C; Mitochondria; Polymers; Polytetrafluoroethylene; Siloxanes; Statistics as Topic; Succinate Dehydrogenase; Temperature; Terpenes; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Comparison of the cytotoxic effects and smear layer removing capacity of oxidative potential water, NaOCl and EDTA.
Topics: Animals; Anti-Infective Agents, Local; Cell Division; Cell Survival; Cells, Cultured; Chelating Agents; Colorimetry; Coloring Agents; Dental Pulp Cavity; Dentin; Edetic Acid; Fibroblasts; Humans; Incisor; Linear Models; Mice; Microscopy, Electron, Scanning; Root Canal Irrigants; Root Canal Preparation; Smear Layer; Sodium Hypochlorite; Tetrazolium Salts; Thiazoles; Water | 2001 |
Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells.
Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Breast Neoplasms; Calcium Channel Blockers; Cell Survival; Doxycycline; Drug Interactions; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Immunoblotting; In Situ Hybridization; Lasers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 2002 |
In vitro cytotoxicity of a composite resin and compomer.
Topics: Apoptosis; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Compomers; Composite Resins; Dental Materials; Dentin; Endothelium; Enzyme Precursors; Humans; L-Lactate Dehydrogenase; Leukemia, Promyelocytic, Acute; Light; Materials Testing; Methacrylates; Necrosis; Pilot Projects; Silicates; Statistics as Topic; Tetrazolium Salts; Thiazoles | 2002 |
Biocompatibility assessment of polytetrafluoroethylene/wollastonite composites using endothelial cells and macrophages.
Topics: Animals; Antigens, CD; B7-2 Antigen; Biocompatible Materials; Calcium Compounds; CD18 Antigens; Cell Division; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Endothelium; Flow Cytometry; Leukocyte Common Antigens; Lipopolysaccharide Receptors; Lymphocytes; Macrophage-1 Antigen; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Neutral Red; Polytetrafluoroethylene; Silicates; Spleen; Temperature; Tetrazolium Salts; Thiazoles | 2001 |
Enhanced antitumor activities of TZT-1027 against TNF-alpha or IL-6 secreting Lewis lung carcinoma in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; DNA, Complementary; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Interleukin-6; LLC-PK1 Cells; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Oligopeptides; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; DNA Damage; DNA Fragmentation; Doxorubicin; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Inhibitory effect of tumor cell proliferation and induction of G2/M cell cycle arrest by panaxytriol.
Topics: 3T3 Cells; Alkynes; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Enediynes; Fatty Alcohols; Flow Cytometry; G2 Phase; Humans; Jurkat Cells; K562 Cells; Medicine, East Asian Traditional; Mice; Mitosis; Molecular Structure; Paclitaxel; Panax; Plant Extracts; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; U937 Cells | 2002 |
Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Flow Cytometry; Glutathione; Humans; Lamiaceae; Medicine, Chinese Traditional; Mitochondria; Molecular Structure; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells.
Topics: Amino Acid Sequence; Animals; Antimetabolites; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cyclic AMP; DNA Replication; Exenatide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Immunohistochemistry; L-Lactate Dehydrogenase; Molecular Sequence Data; Nerve Growth Factor; Neurodegenerative Diseases; PC12 Cells; Peptide Fragments; Peptides; Protein Precursors; Rats; Receptors, Glucagon; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Venoms | 2002 |
Boron compounds against human leukemic cells.
Topics: Apoptosis; Boron Compounds; Cell Division; DNA, Neoplasm; Guanidines; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; U937 Cells | 2001 |
Permeability profiles of M-alkoxysubstituted pyrrolidinoethylesters of phenylcarbamic acid across caco-2 monolayers and human skin.
Topics: Administration, Cutaneous; Algorithms; Caco-2 Cells; Carbamates; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Esters; Humans; In Vitro Techniques; Iontophoresis; Molecular Weight; Permeability; Skin Absorption; Solubility; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2002 |
Down-regulation of proliferation and up-regulation of apoptosis by gonadotropin-releasing hormone agonist in cultured uterine leiomyoma cells.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; Blotting, Western; Buserelin; Cell Count; Cell Division; Cell Separation; Colorimetry; Down-Regulation; fas Receptor; Female; Gonadotropin-Releasing Hormone; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Leiomyoma; Proliferating Cell Nuclear Antigen; Receptors, LHRH; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Up-Regulation; Uterine Neoplasms | 2002 |
Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Division; Docetaxel; Drug Administration Schedule; Female; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Mediastinal Neoplasms; Neoplasms, Experimental; Paclitaxel; Rats; Rats, Nude; Sulindac; Survival Rate; Taxoids; Tetrazolium Salts; Thiazoles | 2002 |
Hypoxia/reoxygenation induces cell injury via different mechanisms in cultured rat cortical neurons and glial cells.
Topics: Animals; Antioxidants; Astrocytes; Cell Death; Cells, Cultured; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Free Radicals; Hypoxia-Ischemia, Brain; L-Lactate Dehydrogenase; Neuroglia; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pregnancy; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazolium Salts; Thiazoles | 2002 |
Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Catalase; Cytochrome P-450 CYP2E1; Cytosol; Enzyme Inhibitors; Flow Cytometry; Genetic Vectors; Glutathione; Humans; Lipid Peroxidation; Membrane Potentials; Mitochondria; Oxygen Consumption; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Carrier Proteins; Cell Division; DNA Primers; Female; Humans; In Situ Hybridization; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 2002 |
Cytotoxicity of trichothecenes and fusarochromanone produced by Fusarium equiseti strains isolated from Norwegian cereals.
Topics: Cell Line; Chromones; Culture Media; Edible Grain; Fusarium; Mycotoxins; Norway; Oryza; Tetrazolium Salts; Thiazoles; Trichothecenes | 2002 |
Delta-aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cell Cycle; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Glucose; Hemin; Humans; Liver Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
The experimental research of R-phycoerythrin subunits on cancer treatment: a new photosensitizer in PDT.
Topics: Animals; Apoptosis; Bone Marrow Cells; Cell Cycle; Cell Division; Dihematoporphyrin Ether; Lasers; Liver Neoplasms, Experimental; Mice; Photochemotherapy; Photosensitizing Agents; Phycoerythrin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin.
Topics: Animals; Apoptosis; Bilirubin; Cell Survival; Cells, Cultured; Cytoskeleton; Glutamic Acid; Neuroglia; Neurons; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2002 |
Influence of different surface modification treatments on poly(D,L-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro.
Topics: Alkaline Phosphatase; Animals; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Fibroins; Insect Proteins; Kinetics; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Polyesters; Polymers; Rats; Silk; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Citrate, beneficial or deleterious in the CNS?
Topics: Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Cerebellum; Chelating Agents; Citrates; Citric Acid Cycle; Coloring Agents; Glucose; L-Lactate Dehydrogenase; Mice; Mitochondria; Neurons; Neuroprotective Agents; Reference Values; Tetrazolium Salts; Thiazoles | 2002 |
Mitochondrial and nonmitochondrial reduction of MTT: interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes.
Topics: Aminoacridines; Benzimidazoles; Carbocyanines; Cell Compartmentation; Energy Metabolism; Eukaryotic Cells; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Intracellular Membranes; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Organometallic Compounds; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
The effect of antioxidants on glycated albumin-induced cytotoxicity in bovine retinal pericytes.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Cell Death; Cell Survival; Cells, Cultured; Chromans; Cytoprotection; Diabetic Retinopathy; Dose-Response Relationship, Drug; Glycated Serum Albumin; Glycation End Products, Advanced; Mitochondria; Oxidative Stress; Pericytes; Probucol; Retina; Retinal Vessels; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Effect of biologically active coating on biocompatibility of Nitinol devices designed for the closure of intra-atrial communications.
Topics: Alloys; Animals; Biocompatible Materials; Blood Platelets; Cells, Cultured; Endothelium, Vascular; Fibronectins; Hemolysis; Heparin; Hirudins; Humans; Immunohistochemistry; Microscopy, Confocal; Microscopy, Electron, Scanning; Partial Thromboplastin Time; Sheep; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2002 |
Anticancer cytotoxicity and nephrotoxicity of the new platinum (II) complexes containing diaminocyclohexane and glycolic acid.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Coloring Agents; Cyclohexanes; DNA; Female; Glucose; Glycolates; Humans; Kidney Cortex; Ligands; Male; Models, Chemical; Ovarian Neoplasms; Platinum Compounds; Prostatic Neoplasms; Rabbits; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tumor Cells, Cultured | 2002 |
Doxorubicin enhances TRAIL-induced apoptosis in prostate cancer.
Topics: Acridine Orange; Anthracyclines; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspases; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Humans; Immunohistochemistry; Male; Membrane Glycoproteins; Prostatic Neoplasms; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells.
Topics: Adenoviridae; Amino Acid Chloromethyl Ketones; Antiviral Agents; Apoptosis; Apoptosis Regulatory Proteins; Caspase Inhibitors; Caspases; Colony-Forming Units Assay; Cysteine Proteinase Inhibitors; Cytochrome c Group; Enzyme Activation; Ganciclovir; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Humans; Membrane Glycoproteins; Neuroblastoma; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Tetrazolium Salts; Thiazoles; Thymidine Kinase; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Coloring Agents; Cysteine; DNA; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Hydrogen Peroxide; Insulin; Islets of Langerhans; Protective Agents; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent mice.
Topics: Animals; Cell Line; Cell Separation; Cell Survival; Chemokine CXCL10; Chemokines, CXC; Coloring Agents; Endothelium; Flow Cytometry; Genetic Therapy; Genetic Vectors; Hemangiosarcoma; Liver; Mice; Mice, Inbred C57BL; Minute Virus of Mice; Neoplasm Metastasis; Parvovirus; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transgenes; Tumor Cells, Cultured | 2002 |
Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants.
Topics: Acyclovir; Animals; Antiviral Agents; Apoptosis; Binding Sites; Blotting, Southern; Blotting, Western; Disease Progression; Dose-Response Relationship, Drug; Flow Cytometry; Ganciclovir; Genetic Therapy; Green Fluorescent Proteins; Guanosine; Humans; Luminescent Proteins; Male; Mice; Mice, SCID; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Prodrugs; Propidium; Prostatic Neoplasms; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Tomography, Emission-Computed; Tumor Cells, Cultured | 2002 |
Betulinic acid inhibits growth factor-induced in vitro angiogenesis via the modulation of mitochondrial function in endothelial cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aorta; Betulinic Acid; Cattle; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Endothelium, Vascular; Fibroblast Growth Factor 2; Growth Substances; Laminin; Mitochondria; Neovascularization, Pathologic; Pentacyclic Triterpenes; Permeability; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Triterpenes | 2002 |
Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells.
Topics: Adenosine; Adenosine Deaminase; Animals; Apoptosis Regulatory Proteins; Brain; CD3 Complex; Cell Division; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Lymphocytes; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mitochondria; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tetrazolium Salts; Theobromine; Thiazoles; Thymidine; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes.
Topics: Animals; Antineoplastic Agents; Astrocytes; Azoles; Cell Line; Cell Survival; Chelating Agents; Cisplatin; Ditiocarb; Glutathione; Hippocampus; Isoindoles; Microscopy, Electron, Scanning; Nerve Tissue Proteins; Neuroprotective Agents; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2002 |
Effects of chitin/chitosan and their oligomers/monomers on migrations of fibroblasts and vascular endothelium.
Topics: Animals; Cell Division; Cell Line; Cell Movement; Cells, Cultured; Chitin; Chitosan; Coloring Agents; Endothelium, Vascular; Fibroblasts; Humans; Mice; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2002 |
Prediction of survival in patients with head and neck cancer using the histoculture drug response assay.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Drug Monitoring; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Survival Rate; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome | 2002 |
Modulation of osteoblast function using poly(D,L-lactic acid) surfaces modified with alkylation derivative of chitosan.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Biocompatible Materials; Cell Division; Cell Survival; Cells, Cultured; Chitin; Chitosan; Coloring Agents; Kinetics; Lactic Acid; Membranes, Artificial; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Polyesters; Polymers; Rats; Skull; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2002 |
Induction of microsomal epoxide hydrolase by sulfur amino acid deprivation via the pathway of C-Jun N-terminal kinase and its extracellular exposure during cell death.
Topics: Amino Acids, Sulfur; Animals; bcl-2-Associated X Protein; Blotting, Northern; Caspase 3; Caspase Inhibitors; Caspases; Cell Death; Cytochrome c Group; Enzyme Induction; Enzyme Inhibitors; Epoxide Hydrolases; Fluorescent Antibody Technique; Immunoenzyme Techniques; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Microsomes; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Mitogenic effect of L-dopa on human periodontal ligament fibroblast cells.
Topics: Cells, Cultured; Coloring Agents; Dopamine Agents; Fibroblasts; Humans; Levodopa; Mitosis; Periodontal Ligament; Tetrazolium Salts; Thiazoles; Tissue Preservation | 2002 |
Suppression of the basic transcription element-binding protein in brain neuronal cultures inhibits thyroid hormone-induced neurite branching.
Topics: Acetylcholinesterase; Animals; Blotting, Northern; Blotting, Western; Brain Chemistry; Cells, Cultured; Chromatography, Affinity; DNA-Binding Proteins; Electrophoresis; Female; Gene Expression Regulation; Kruppel-Like Transcription Factors; Neurites; Neurons; Oligonucleotides, Antisense; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transcription Factors; Triiodothyronine; Tubulin; Up-Regulation | 2002 |
Lisofylline, a novel antiinflammatory agent, protects pancreatic beta-cells from proinflammatory cytokine damage by promoting mitochondrial metabolism.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Cytokines; DNA Damage; Fluorescent Dyes; In Situ Nick-End Labeling; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Membranes; Mitochondria; Pentoxifylline; Rats; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2002 |
Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; Cell Division; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Humans; Interleukin-6; Interleukin-8; Mitoxantrone; Osteosarcoma; Paclitaxel; Phenotype; RNA; Tetrazolium Salts; Thiazoles; Time Factors; Topotecan; Transfection; Tumor Cells, Cultured | 2002 |
Abietane diterpenoids from Coleus xanthanthus.
Topics: Antineoplastic Agents, Phytogenic; Diterpenes; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Lamiaceae; Leukemia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Induction of MnSOD gene by arachidonic acid is mediated by reactive oxygen species and p38 MAPK signaling pathway in human HepG2 hepatoma cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; DNA Primers; Enzyme Induction; Enzyme Inhibitors; Flow Cytometry; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Effect of squalene monohydroperoxide on cytotoxicity and cytokine release in a three-dimensional human skin model and human epidermal keratinocytes.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Cytokines; Cytological Techniques; Humans; In Vitro Techniques; Indicators and Reagents; Interleukin-2; Keratinocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Skin; Squalene; Tetrazolium Salts; Thiazoles | 2002 |
Enhanced anti-tumor effect of trastuzumab in combination with cisplatin.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab; Tumor Cells, Cultured | 2002 |
Resinous perforation-repair materials inhibit the growth, attachment, and proliferation of human gingival fibroblasts.
Topics: Biocompatible Materials; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Compomers; Composite Resins; Dental Cements; Fibroblasts; Gingiva; Glass Ionomer Cements; Humans; Materials Testing; Resin Cements; Resins, Synthetic; Root Canal Filling Materials; Spectrophotometry; Statistics as Topic; Tetrazolium Salts; Thiazoles | 2002 |
Tumoricidal effect of macrophages on transplantable melanoma cells with regard to their sensitivity to exogenous cytokines.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cricetinae; Cytokines; Cytotoxicity, Immunologic; Macrophages; Male; Melanoma, Experimental; Mesocricetus; Oncostatin M; Peptides; Skin; Tetrazolium Salts; Thiazoles | 2002 |
Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Breast Neoplasms; Cell Division; Cell Survival; Drug Interactions; Estrogens, Non-Steroidal; Flavonoids; Humans; Isoflavones; Kaempferols; Phytoestrogens; Plant Extracts; Plant Preparations; Plants; Quercetin; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E | 2002 |
Reduction of trophic support enhances apoptosis in PC12 cells expressing Alzheimer's APP mutation and sensitizes cells to staurosporine-induced cell death.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Culture Media; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Mutation; Neurons; Oxidative Stress; PC12 Cells; Rats; Staurosporine; Tetrazolium Salts; Thiazoles | 2002 |
Inhibition by arsenic trioxide of human hepatoma cell growth.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Humans; Oxides; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2002 |
Utility of MTT assay in three-dimensional cultured human skin model as an alternative for draize skin irritation test: approach using diffusion law of irritant in skin and toxicokinetics-toxicodynamics correlation.
Topics: Animals; Cetylpyridinium; Chromatography, High Pressure Liquid; Colorimetry; Coloring Agents; Guinea Pigs; Humans; In Vitro Techniques; Irritants; Male; Models, Biological; Predictive Value of Tests; Skin; Skin Tests; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2002 |
Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Apoptosis; Blotting, Southern; Blotting, Western; Cell Survival; Cells, Cultured; Coloring Agents; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Insulin-Like Growth Factor I; Keratinocytes; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidine Dimers; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymine; Time Factors; Ultraviolet Rays | 2002 |
The mycotoxin patulin alters the barrier function of the intestinal epithelium: mechanism of action of the toxin and protective effects of glutathione.
Topics: Antidotes; Cells, Cultured; Chlorides; Drug Antagonism; Electrophysiology; Epithelium; Ethylmaleimide; Glucose; Glutathione; Humans; Intestinal Absorption; Intestinal Mucosa; L-Lactate Dehydrogenase; Mycotoxins; Patulin; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 2002 |
Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary.
Topics: Adenocarcinoma, Clear Cell; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cisplatin; Coloring Agents; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Glutathione; Humans; Inhibitory Concentration 50; Irinotecan; Mitochondrial Proteins; Mitomycin; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Amiodarone induces apoptosis in L-132 human lung epithelial cell line.
Topics: Amiodarone; Anti-Arrhythmia Agents; Apoptosis; Caspase 3; Caspases; Cell Line; Coloring Agents; DNA Fragmentation; Epithelial Cells; Flow Cytometry; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Lung; Pulmonary Alveoli; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2002 |
Effects of superporous hydrogels on paracellular drug permeability and cytotoxicity studies in Caco-2 cell monolayers.
Topics: Acrylic Resins; Algorithms; Antineoplastic Agents; Biological Transport, Active; Caco-2 Cells; Cell Survival; Coloring Agents; Dextrans; Electric Conductivity; Humans; Hydrogels; Mannitol; Molecular Weight; Permeability; Porosity; Propidium; Tetrazolium Salts; Thiazoles; Trypan Blue | 2002 |
Cytotoxic constituents from Aquilegia ecalcarata.
Topics: Acetonitriles; Alkaloids; Cyclohexenes; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Quinolones; Ranunculaceae; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Sensitivity of transplantable melanoma cells to cytokines with regard to their spontaneous apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cricetinae; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Interleukin-6; Male; Melanoma; Melanoma, Amelanotic; Neoplasm Transplantation; Oncostatin M; Peptides; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Comparison of chemosensitivity tests: clonogenic assay versus MTT assay.
Topics: Antineoplastic Agents; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2002 |
Comparison between the mechanisms of action of plant toxins ricin and viscumin on the stage of intracellular dissociation.
Topics: Animals; Antibodies, Monoclonal; Antibody-Producing Cells; Antineoplastic Agents, Phytogenic; Biotin; Cell Survival; Dithiothreitol; Epitopes; Hybridomas; Immunoenzyme Techniques; Mice; Plant Preparations; Plant Proteins; Ribosome Inactivating Proteins, Type 2; Ricin; Tetrazolium Salts; Thiazoles; Toxins, Biological | 2002 |
Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line; Cell Nucleus; Chemokines, CC; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Antisense oligonucleotides specific to mutated K-ras genes inhibit invasiveness of human pancreatic cancer cell lines.
Topics: Blotting, Western; Cell Line; Coloring Agents; DNA, Neoplasm; Genes, ras; Humans; Mutation; Neoplasm Invasiveness; Oligonucleotides, Antisense; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured | 2001 |
Potentiation of antiproliferative effects of tamoxifen and ethanol on mouse hepatoma cells by melatonin: possible involvement of mitogen-activated protein kinase and induction of apoptosis.
Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Liver Neoplasms; Melatonin; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Biology; Phosphorylation; Tamoxifen; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid.
Topics: Active Transport, Cell Nucleus; Alzheimer Disease; Amyloid; Animals; Antioxidants; Apoptosis; Astrocytes; Cells, Cultured; DNA; Gene Expression; Humans; L-Lactate Dehydrogenase; Mitochondria; Nerve Tissue Proteins; Neurons; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Synucleins; Tetrazolium Salts; Thiazoles | 2002 |
Regulation of endothelial cell proliferation by nitric oxide.
Topics: Animals; Biopterins; Blotting, Western; Cell Division; Coloring Agents; Coronary Vessels; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Muscle, Skeletal; NADP; Nitric Oxide; Proliferating Cell Nuclear Antigen; Rats; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors | 2002 |
Calretinin and calbindin D-28k, but not parvalbumin protect against glutamate-induced delayed excitotoxicity in transfected N18-RE 105 neuroblastoma-retina hybrid cells.
Topics: Animals; Blotting, Western; Brain Neoplasms; Calbindin 2; Calbindins; Cell Division; Cell Line; Clone Cells; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Hybrid Cells; Immunohistochemistry; Mice; Neuroblastoma; Parvalbumins; Plasmids; Rats; Retina; S100 Calcium Binding Protein G; Tetrazolium Salts; Thiazoles; Transfection | 2002 |
Retinoic acid modulates the radiosensitivity of head-and-neck squamous carcinoma cells grown in collagen gel.
Topics: Cell Division; Collagen; Dose-Response Relationship, Drug; Endothelium, Vascular; Epithelial Cells; Gels; Head and Neck Neoplasms; Humans; Hyaluronic Acid; Immunohistochemistry; Phenotype; Tetrazolium Salts; Thiazoles; Time Factors; Tretinoin; Tumor Cells, Cultured | 2002 |
Structure-activity relationship of triterpenoids isolated from Mitragyna stipulosa on cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Korea; Magnetic Resonance Spectroscopy; Mitragyna; Plant Bark; Plant Extracts; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triterpenes | 2002 |
Protective effect of fangchinoline on cyanide-induced neurotoxicity in cultured rat cerebellar granule cells.
Topics: Alkaloids; Animals; Antioxidants; Benzylisoquinolines; Calcium; Cell Death; Cells, Cultured; Cerebellum; Coloring Agents; Cyanides; Cytoplasmic Granules; Glutamic Acid; Neurons; Neurotoxicity Syndromes; Oxidants; Rats; Rats, Sprague-Dawley; Stephania; Tetrazolium Salts; Thiazoles; Trypan Blue | 2002 |
Cytotoxic effect of nitric oxide on human hematological malignant cells.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Leukemia, Myeloid; Lymphoma; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Tetrazolium Salts; Thiazoles | 2002 |
Cross-resistance to five glucocorticoids in childhood acute lymphoblastic and non-lymphoblastic leukemia samples tested by the MTT assay: preliminary report.
Topics: Adolescent; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Glucocorticoids; Humans; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles | 2002 |
The influence of intracellular idarubicin and daunorubicin levels on drug cytotoxicity in childhood acute leukemia.
Topics: Adolescent; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Child, Preschool; Daunorubicin; Flow Cytometry; Humans; Idarubicin; Infant; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles | 2002 |
Implication of extracellular zinc exclusion by recombinant human calprotectin (MRP8 and MRP14) from target cells in its apoptosis-inducing activity.
Topics: Animals; Apoptosis; Calgranulin A; Calgranulin B; Chelating Agents; DNA Fragmentation; Dose-Response Relationship, Immunologic; Ethylenediamines; Humans; Macromolecular Substances; Male; Mice; Mice, Inbred C3H; Pentetic Acid; Protein Subunits; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Zinc | 2002 |
Derivatives of dehydrocrotonin, a diterpene lactone isolated from Croton cajucara: cytotoxicity in rat cultured hepatocytes and in V79 cells.
Topics: Animals; Cell Line; Cell Survival; Cellular Senescence; Cimetidine; Cricetinae; Cricetulus; Croton; Culture Media, Conditioned; Diterpenes; Diterpenes, Clerodane; DNA; Dose-Response Relationship, Drug; Fibroblasts; Hepatocytes; Male; Neutral Red; Plants, Medicinal; Rats; Rats, Wistar; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2002 |
Ethanol decreases basal insulin secretion from HIT-T15 cells.
Topics: Cell Line; Cell Survival; Depression, Chemical; Ethanol; Humans; Immunohistochemistry; Insulin; Islets of Langerhans; L-Lactate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2002 |
An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Small Cell; Cisplatin; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Flow Cytometry; Gangliosides; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Mitogen-Activated Protein Kinases; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2002 |
Matrix metalloproteinase inhibitor, marimastat, decreases peritoneal spread of gastric carcinoma in nude mice.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Body Weight; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hydroxamic Acids; Male; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Peritoneum; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2002 |
Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells.
Topics: Animals; Apoptosis; Blotting, Western; Carrier Proteins; Coloring Agents; Culture Media, Serum-Free; Cytokines; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; In Situ Nick-End Labeling; MAP Kinase Signaling System; Midkine; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Neuroprotective Agents; PC12 Cells; Rats; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 1999 |
Microencapsulation of cells producing therapeutic proteins: optimizing cell growth and secretion.
Topics: Alginates; Calcium Chloride; Cell Division; Cell Line; Cell Survival; Collagen; Coloring Agents; Endostatins; Enzyme-Linked Immunosorbent Assay; Genetic Engineering; Genetic Therapy; Hepatocyte Growth Factor; Humans; Microscopy, Confocal; Microspheres; Peptide Fragments; Polylysine; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2002 |
Alcohol induces apoptosis in TM3 mouse Leydig cells via bax-dependent caspase-3 activation.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Cell Survival; Central Nervous System Depressants; DNA Fragmentation; Enzyme Activation; Ethanol; Fluorescent Dyes; Genes, bcl-2; In Situ Nick-End Labeling; Indoles; Leydig Cells; Male; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2002 |
Supra-additive antitumor activity of 5FU with tumor necrosis factor-related apoptosis-inducing ligand on gastric and colon cancers in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Cell Division; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; HT29 Cells; Humans; Membrane Glycoproteins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Selective cytotoxicity of gemcitabine in bladder cancer cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Coculture Techniques; Coloring Agents; Deoxycytidine; Fibroblasts; Gemcitabine; Humans; Immunohistochemistry; Rats; Spheroids, Cellular; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 2002 |
Synchrotron infrared spectromicroscopy as a novel bioanalytical microprobe for individual living cells: cytotoxicity considerations.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA; Humans; Infrared Rays; Microscopy; NAD; Optics and Photonics; Spectroscopy, Fourier Transform Infrared; Synchrotrons; Tetrazolium Salts; Thiazoles | 2002 |
Superoxide anion in Anopheles albimanus hemolymph and midgut is toxic to Plasmodium berghei ookinetes.
Topics: Animals; Anopheles; Dihydroxyphenylalanine; Female; Free Radical Scavengers; Hemolymph; Host-Parasite Interactions; Melanins; Perfusion; Plasmodium berghei; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 2002 |
Augmented antitumour effects of combination therapy with TNP-470 and chemoimmunotherapy in mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Cell Division; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexanes; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Immunotherapy; Interferon-gamma; Interleukin-12; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2002 |
Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Methotrexate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Sulfinosine-induced cell growth inhibition and apoptosis in human lung carcinomas in vitro.
Topics: Antineoplastic Agents; Apoptosis; Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Survival; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Purine Nucleosides; Tetrazolium Salts; Thiazoles; Trypan Blue; Tumor Cells, Cultured | 2002 |
In vitro cytotoxicity of the organophosphorus insecticide methylparathion to FG-9307, the gill cell line of flounder (Paralichthys olivaceus).
Topics: Animals; Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Flounder; Inhibitory Concentration 50; Insecticides; Methyl Parathion; Microscopy, Electron; Mitochondria; Necrosis; Tetrazolium Salts; Thiazoles | 2002 |
DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: bolus addition versus continuous generation of H(2)O(2).
Topics: Apoptosis; Blotting, Western; Caspases; Cell Survival; Coloring Agents; Comet Assay; DNA Damage; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Humans; Hydrogen Peroxide; Jurkat Cells; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Improvement of the functions of osteoblasts seeded on modified poly(D,L-lactic acid) with poly(aspartic acid).
Topics: Alkaline Phosphatase; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Cells, Immobilized; Chemical Phenomena; Chemistry, Physical; Humans; Lactic Acid; Materials Testing; Membranes, Artificial; Osteoblasts; Peptides; Polyesters; Polymers; Proteins; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
New acrylic bone cements conjugated to vitamin E: curing parameters, properties, and biocompatibility.
Topics: Acrylates; Alkaline Phosphatase; Antioxidants; Biocompatible Materials; Bone Cements; Cell Division; Cell Survival; Coloring Agents; Free Radicals; Humans; Materials Testing; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Weight; Osteoblasts; Oxazines; Phenotype; Prostheses and Implants; Succinate Dehydrogenase; Surface Properties; Tetrazolium Salts; Thiazoles; Vitamin E; Xanthenes | 2002 |
Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac.
Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Blotting, Western; Cardiomegaly; Cells, Cultured; Coloring Agents; Enzyme Activation; Heart; Lovastatin; Mitogen-Activated Protein Kinases; Myocardium; Phenylephrine; Phosphorylation; Pravastatin; Propidium; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2001 |
Cultured rat vascular smooth muscle cells are resistant to methylamine toxicity: no correlation to semicarbazide-sensitive amine oxidase.
Topics: Amine Oxidase (Copper-Containing); Animals; Cells, Cultured; Clone Cells; Colony-Forming Units Assay; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Formaldehyde; Methylamines; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2001 |
Augmentation of macrophage antitumor activities and nitric oxide production by oregonin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Separation; Cytotoxicity Tests, Immunologic; Diarylheptanoids; In Vitro Techniques; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Neoplasms; Neoplasms, Experimental; Nitric Oxide; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Enhancement of NK cytotoxicity, antimetastasis and elongation effect of survival time in B16-F10 melanoma cells by oregonin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Separation; Cytotoxicity Tests, Immunologic; Diarylheptanoids; Killer Cells, Natural; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Neoplasm Metastasis; Stimulation, Chemical; Survival; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Inhibition of angiogenesis by propolis.
Topics: Angiogenesis Inhibitors; Animals; Caffeic Acids; Cattle; Cell Division; Chick Embryo; Chorion; Endothelium, Vascular; Ethanol; Keratolytic Agents; Membranes; Phenylethyl Alcohol; Propolis; Pulmonary Artery; Solvents; Tetrazolium Salts; Thiazoles; Tretinoin | 2002 |
Which dosing scheme is suitable for the taxanes? An in vitro model.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Division; Cell Survival; Docetaxel; Female; Humans; Indicators and Reagents; Paclitaxel; Taxoids; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
A flow cytometry-based assay for quantitative analysis of cellular proliferation and cytotoxicity in vitro.
Topics: Adult; Cell Division; Cytotoxicity Tests, Immunologic; Flow Cytometry; Humans; Lymphocyte Activation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors.
Topics: 5' Untranslated Regions; Animals; Base Sequence; Blotting, Western; Cell Division; Coloring Agents; Growth Hormone; Humans; Inhibitory Concentration 50; Male; Models, Chemical; Molecular Sequence Data; Oligonucleotides, Antisense; Peptide Nucleic Acids; Proto-Oncogene Proteins c-myc; Rats; Receptors, Somatostatin; RNA, Messenger; Somatostatin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 2. Viability of encapsulated marrow stromal osteoblasts cultured on crosslinking poly(propylene fumarate).
Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Bone Substitutes; Cell Division; Cell Survival; Chromatography; Coloring Agents; Cross-Linking Reagents; DNA; Drug Compounding; Drug Delivery Systems; Fumarates; Gelatin; Gels; Injections; Osteoblasts; Osteocalcin; Phenotype; Polymers; Polypropylenes; Rats; Rats, Sprague-Dawley; Temperature; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tissue Engineering | 2002 |
Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes.
Topics: Adenoviridae; Animals; Apoptosis; Brain; Brain Neoplasms; Cell Division; Combined Modality Therapy; Cytosine Deaminase; Flow Cytometry; Fluorouracil; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Lac Operon; Male; Nucleoside Deaminases; Pentosyltransferases; Radiotherapy; Rats; Rats, Wistar; Survival Rate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
Does LLLT stimulate laryngeal carcinoma cells? An in vitro study.
Topics: Analysis of Variance; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Humans; Laryngeal Neoplasms; Low-Level Light Therapy; Optics and Photonics; Radiation Dosage; Spectrum Analysis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Improved method for in vitro assessment of dermal toxicity for volatile organic chemicals.
Topics: Animals; Coloring Agents; Fibroblasts; Irritants; Male; Occupational Exposure; Rats; Rats, Inbred F344; Skin; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xylenes | 2002 |
Immunosuppressants leflunomide and mycophenolic acid inhibit fibroblast IL-6 production by distinct mechanisms.
Topics: Aniline Compounds; Animals; Cell Line; Cell Survival; Cells, Cultured; Coloring Agents; Crotonates; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Guanidines; Humans; Hydroxybutyrates; Immunosuppressive Agents; Interferon-gamma; Interleukin-6; Isoxazoles; Leflunomide; Macrophages; Mice; Mycophenolic Acid; Nitric Oxide Synthase; Nitriles; omega-N-Methylarginine; Phosphodiesterase Inhibitors; Rolipram; Tetrazolium Salts; Thiazoles; Time Factors; Toluidines | 2002 |
Cytotoxicity of resin-based restorative materials on human pulp cell cultures.
Topics: Analysis of Variance; Cells, Cultured; Coloring Agents; Compomers; Composite Resins; Dental Pulp; Dental Restoration, Permanent; Glass Ionomer Cements; Humans; Methacrylates; Mitochondria; Resins, Synthetic; Silicates; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2002 |
Mitogenic properties of insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary culture.
Topics: Biomarkers; Blotting, Western; Breast; Cell Division; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Epithelial Cells; Female; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Tetrazolium Salts; Thiazoles | 2002 |
A three-dimensional osteochondral composite scaffold for articular cartilage repair.
Topics: Analysis of Variance; Biocompatible Materials; Biodegradation, Environmental; Cartilage, Articular; Collagen; DNA; Glycosaminoglycans; Humans; Lactic Acid; Microscopy, Electron, Scanning; Osteoarthritis; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles; Wound Healing | 2002 |
Growth of human endothelial cells on photochemically grafted Gly-Arg-Gly-Asp (GRGD) chitosans.
Topics: Biocompatible Materials; Cell Adhesion; Cell Division; Cell Survival; Chitin; Chitosan; Coloring Agents; Endothelium, Vascular; Humans; Models, Chemical; Oligopeptides; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2002 |
Coating with genetic engineered hydrophobin promotes growth of fibroblasts on a hydrophobic solid.
Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; Cells, Cultured; Coated Materials, Biocompatible; Coloring Agents; Fibroblasts; Fungal Proteins; Gene Deletion; Genetic Engineering; Mice; Molecular Sequence Data; Peptides; Polytetrafluoroethylene; Protein Structure, Tertiary; Schizophyllum; Sequence Homology, Amino Acid; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
SN-38 induces cell cycle arrest and apoptosis in human testicular cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Line; Cisplatin; DNA; Etoposide; G1 Phase; Humans; In Situ Nick-End Labeling; Irinotecan; Male; Testicular Neoplasms; Tetrazolium Salts; Thiazoles | 2002 |
Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation.
Topics: Apoptosis; Blotting, Western; Cell Survival; Colforsin; Culture Media, Serum-Free; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Humans; In Situ Nick-End Labeling; Luciferases; Microscopy, Fluorescence; Mutation; Neuroblastoma; Neurons; Nitric Oxide; Nitrites; Phosphorylation; Plasmids; Protein Isoforms; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations.
Topics: Animals; Apoptosis; Cell Cycle; Cell Survival; Coloring Agents; Cyclin A; Cyclin A1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Damage; Drug Screening Assays, Antitumor; In Situ Nick-End Labeling; Isoenzymes; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; RNA, Messenger; Sulfonamides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Fractionated irradiation of H69 small-cell lung cancer cells causes stable radiation and drug resistance with increased MRP1, MRP2, and topoisomerase IIalpha expression.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Survival; Cisplatin; Coloring Agents; DNA Topoisomerases, Type II; Dose Fractionation, Radiation; Drug Resistance, Neoplasm; Gene Expression; Glutathione; Humans; Lung Neoplasms; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cladribine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplastic Stem Cells; Recurrence; Remission Induction; Tetrazolium Salts; Thiazoles; Translocation, Genetic; Trisomy | 2002 |
Antineoplastic effect of new boron compounds against leukemic cell lines and cells from leukemic patients.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Boron Compounds; Cell Division; Guanidines; HL-60 Cells; Humans; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Tetrazolium Salts; Thiazoles; Thymidine; U937 Cells | 2002 |
Differential modulation of growth and glutathione metabolism in cultured rat astrocytes by 4-hydroxynonenal and green tea polyphenol, epigallocatechin-3-gallate.
Topics: Aldehydes; Animals; Apoptosis; Astrocytes; Blotting, Western; Catechin; Flavonoids; Glutathione; Glutathione Transferase; Immunohistochemistry; Isoenzymes; Lipid Peroxidation; Mitochondria; Oxidative Stress; Phenols; Polymers; Rats; Rats, Wistar; Tea; Tetrazolium Salts; Thiazoles | 2002 |
Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT).
Topics: Amyloid beta-Peptides; Antibodies; Biomarkers; Chromones; Coloring Agents; Endosomes; Enzyme Inhibitors; HeLa Cells; Humans; Immunohistochemistry; Membrane Proteins; Mitogen-Activated Protein Kinases; Morpholines; Oxidation-Reduction; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rab5 GTP-Binding Proteins; Tetrazolium Salts; Thiazoles; Vesicular Transport Proteins | 2002 |
Novel non-labile covalent binding of sulfamethoxazole reactive metabolites to cultured human lymphoid cells.
Topics: Animals; Anti-Infective Agents; Antibodies; Biotransformation; Blotting, Western; Cytosol; Cytotoxicity Tests, Immunologic; Humans; Hydroxylation; Microsomes, Liver; Protein Binding; Rats; Rats, Sprague-Dawley; Sulfamethoxazole; Tetrazolium Salts; Thiazoles; U937 Cells | 2002 |
Unsaturated fatty acids bind Myc-Max transcription factor and inhibit Myc-Max-DNA complex formation.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Basic-Leucine Zipper Transcription Factors; Binding, Competitive; cdc25 Phosphatases; Dimerization; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Electrophoretic Mobility Shift Assay; Fatty Acids, Unsaturated; Gene Expression Regulation; Humans; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Binding; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
In vitro and in vivo assays for the proliferative and vascular permeabilization activities of vascular endothelial growth factor (VEGF) and its receptor.
Topics: Animals; Capillary Permeability; Cell Division; Cells, Cultured; Endothelial Growth Factors; Endothelium, Vascular; Humans; Immunoglobulin G; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Thymidine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
The hollow fiber assay.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Division; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Membranes, Artificial; Mice; Mice, Nude; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
The anticorrosion ability of titanium nitride (TiN) plating on an orthodontic metal bracket and its biocompatibility.
Topics: Cell Line; Coated Materials, Biocompatible; Colorimetry; Corrosion; Electrochemistry; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Materials Testing; Metals; Orthodontic Brackets; Saliva, Artificial; Stainless Steel; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2002 |
Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility.
Topics: Animals; Cell Adhesion; Cell Division; Cells, Cultured; Chitin; Chitosan; Chondrocytes; Coated Materials, Biocompatible; Collagen; Gelatin; In Vitro Techniques; Lactic Acid; Macromolecular Substances; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Polymethyl Methacrylate; Rabbits; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
Management of oxidative stress by heme oxygenase-1 in cisplatin-induced toxicity in renal tubular cells.
Topics: Acetylcysteine; alpha-Tocopherol; Animals; Antioxidants; Blotting, Western; Cell Line; Cell Survival; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Kidney Tubules; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Swine; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Effects of 5-aminolevulinic acid on the glutamatergic neurotransmission.
Topics: Aminolevulinic Acid; Animals; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Female; Glutamic Acid; Humans; Kinetics; Nerve Tissue Proteins; Rats; Rats, Wistar; Synaptic Transmission; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 2003 |
The effects of the total saponin of Dipsacus asperoides on the damage of cultured neurons induced by beta-amyloid protein 25-35.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Hydro-Lyases; Lipid Peroxidation; Malondialdehyde; Neurons; Neuroprotective Agents; Oleanolic Acid; Oxidative Stress; Peptide Fragments; Rats; Saponins; Tetrazolium Salts; Thiazoles | 2002 |
Reaction of poly(acrylamide-co-vinylamine) with tresyl-PEG in the presence of PC12 cells.
Topics: Amines; Animals; Biocompatible Materials; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Compounding; Hydrolysis; PC12 Cells; Polyethylene Glycols; Polymers; Rats; Tetrazolium Salts; Thiazoles; Trypan Blue | 2003 |
Influence of uremia on cell viability and cytokine release of human peritoneal mesothelial cells.
Topics: Adenosine Triphosphate; Adult; Cell Survival; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelium; Female; Humans; Immunohistochemistry; Interleukin-1; Interleukin-6; Interleukin-8; Kidney Failure, Chronic; Luminescent Measurements; Male; Middle Aged; Peritoneal Cavity; Protein Biosynthesis; Tetrazolium Salts; Thiazoles; Uremia | 2002 |
Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Division; Cell Line; Chick Embryo; In Vitro Techniques; Models, Biological; Monoterpenes; Neoplasm Metastasis; Neuroglia; Tetrazolium Salts; Thiazoles | 2002 |
Modulation of endothelial permeability by 1-O-alkylglycerols.
Topics: Albumins; Animals; Aorta; Calcimycin; Cell Membrane Permeability; Cells, Cultured; Coloring Agents; Diglycerides; Endothelium, Vascular; Glycerol; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2002 |
TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney.
Topics: Animals; Coloring Agents; Dose-Response Relationship, Drug; Hydrogen Peroxide; Immunohistochemistry; Kidney; Kidney Diseases; Male; Mice; Nitrogen; Oxidative Stress; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Tetrazolium Salts; Thiazoles; Triacetoneamine-N-Oxyl; Tyrosine; Urine | 2002 |
Influence of lithium on growth and viability of thyroid follicular cells.
Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Chromium Radioisotopes; Lithium; Rats; Tetrazolium Salts; Thiazoles; Thymidine; Thyroid Gland; Thyrotropin | 2002 |
Cytotoxicity of dentine-bonding agents on human pulp cells in vitro.
Topics: Acrylates; Acrylic Resins; Analysis of Variance; Biocompatible Materials; Bisphenol A-Glycidyl Methacrylate; Cell Culture Techniques; Coloring Agents; Dental Pulp; Dentin-Bonding Agents; Humans; Polymethacrylic Acids; Resin Cements; Statistics as Topic; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Pyrrolizidine alkaloid clivorine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein kinase in L-02 cells.
Topics: Blotting, Western; Cell Division; Cell Survival; Enzyme Activation; Fluorescent Antibody Technique, Indirect; HeLa Cells; Humans; Liver; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocrotaline; p38 Mitogen-Activated Protein Kinases; Pyrrolizidine Alkaloids; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
A novel compound RS-0466 reverses beta-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Coloring Agents; Excitatory Postsynaptic Potentials; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Neurons; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Triazines | 2002 |
Cytotoxic potential of industrial strains of Bacillus sp.
Topics: Animals; Antibodies, Bacterial; Bacillus cereus; Biological Assay; CHO Cells; Cricetinae; Culture Media, Conditioned; Dose-Response Relationship, Drug; Enterotoxins; Environmental Microbiology; Mesocricetus; Tetrazolium Salts; Thiazoles | 2002 |
Activation of NMDA receptor partly involved in beta-bungarotoxin-induced neurotoxicity in cultured primary neurons.
Topics: Animals; Antioxidants; Bungarotoxins; Caspases; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kinetics; Male; Neurites; Neurons; Neurotoxins; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles | 2003 |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity.
Topics: Anesthetics, Intravenous; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; Butyrates; Cell Cycle; Cell Line; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Depsipeptides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; G2 Phase; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; Immunoblotting; Jurkat Cells; Mitosis; Peptides; Peptides, Cyclic; Protein Synthesis Inhibitors; Sodium Oxybate; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Tubulin; Tumor Cells, Cultured | 2002 |
The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Benzopyrans; Blotting, Western; Caspase Inhibitors; Caspases; Cell Survival; Cell-Free System; Cells, Cultured; Coloring Agents; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; In Situ Nick-End Labeling; Isoquinolines; Mice; Microscopy, Fluorescence; Mitochondria; Nitriles; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells.
Topics: Benzeneacetamides; Cell Division; Cell Survival; Colorimetry; DNA Fragmentation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Humans; Leukemia; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT.
Topics: Animals; Apoptosis; Binding, Competitive; Blotting, Western; Cell Death; Cell Separation; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Doxorubicin; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Ghrelin; Indoles; Inhibitory Concentration 50; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Oligopeptides; Peptide Hormones; Peptides; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spiro Compounds; Swine; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Cisplatin potentiates 1,25-dihydroxyvitamin D3-induced apoptosis in association with increased mitogen-activated protein kinase kinase kinase 1 (MEKK-1) expression.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Calcitriol; Cell Survival; Cisplatin; Coloring Agents; DNA Adducts; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Serine-Threonine Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Up-Regulation | 2002 |
Mechanisms regulating the cadmium-mediated suppression of Sp1 transcription factor activity in alveolar epithelial cells.
Topics: Animals; Apoptosis; Blotting, Western; Cadmium; Cadmium Radioisotopes; Cell Line; Cell Nucleus; Culture Media; Dose-Response Relationship, Drug; Down-Regulation; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Nuclear Proteins; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Proteins; Pulmonary Alveoli; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Cadmium exposure down-regulates 8-oxoguanine DNA glycosylase expression in rat lung and alveolar epithelial cells.
Topics: Animals; Blotting, Western; Cadmium; Cell Line; Cell Survival; DNA-Formamidopyrimidine Glycosylase; Down-Regulation; Epithelial Cells; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Lung; Male; N-Glycosyl Hydrolases; Propidium; Pulmonary Alveoli; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2003 |
The flame retardants tetrabromobisphenol A and tetrabromobisphenol A-bisallylether suppress the induction of interleukin-2 receptor alpha chain (CD25) in murine splenocytes.
Topics: Animals; Cell Separation; Cell Survival; Cytochrome P-450 CYP1A1; Cytokines; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Female; Flame Retardants; Hepatocytes; Immunohistochemistry; Indicators and Reagents; Interleukin-2; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Polybrominated Biphenyls; Receptors, Interleukin-2; Solutions; Spleen; Tetrazolium Salts; Thiazoles | 2003 |
Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Free Radicals; Fructosediphosphates; Glutathione; Glutathione Reductase; Intracellular Fluid; Mice; Molsidomine; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2003 |
Expression of IGFBP-3 by human retinal endothelial cell cultures: IGFBP-3 involvement in growth inhibition and apoptosis.
Topics: Amides; Annexin A5; Apoptosis; Cell Culture Techniques; Cell Division; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Humans; Indoles; Insulin-Like Growth Factor Binding Protein 3; Nitrobenzenes; Receptors, Somatostatin; Recombinant Proteins; Retinal Vessels; Tetrazolium Salts; Thiazoles | 2003 |
In vitro bioassay for transforming growth factor-beta using XTT method.
Topics: Animals; Cell Line; Cell Survival; Coloring Agents; Epithelial Cells; Genes, ras; Growth Inhibitors; Humans; Mink; Spectrophotometry; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 2002 |
Synthesis and biological activity of a platinum(II) 6-phenyl-2,2'-bipyridine complex and its dimeric analogue.
Topics: Algorithms; Antineoplastic Agents; DNA; DNA Fragmentation; Drug Screening Assays, Antitumor; Electrophoretic Mobility Shift Assay; Humans; Indicators and Reagents; Nucleic Acid Conformation; Organoplatinum Compounds; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thermodynamics; Thiazoles; Tumor Cells, Cultured; Viscosity | 2003 |
Lipopolysaccharide enhances the cytotoxicity of 2-chloroethyl ethyl sulfide.
Topics: Adjuvants, Immunologic; Animals; Cell Death; Cell Line; Chemical Warfare Agents; Cytokines; Drug Synergism; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mustard Gas; Propidium; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Multiplex gene expression analysis for high-throughput drug discovery: screening and analysis of compounds affecting genes overexpressed in cancer cells.
Topics: Actins; Apoptosis; CCAAT-Enhancer-Binding Proteins; Coloring Agents; Cyclophilins; DNA; Drug Design; GADD45 Proteins; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Kinetics; Male; Models, Chemical; Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Prostatic Neoplasms; Proteins; RNA, Messenger; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured; Up-Regulation | 2002 |
Overcoming multidrug drug resistance in P-glycoprotein/MDR1-overexpressing cell lines by ecteinascidin 743.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Coloring Agents; Dioxoles; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Inhibitory Concentration 50; Isoquinolines; Models, Chemical; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles; Time Factors; Trabectedin; Tumor Cells, Cultured; Vincristine | 2002 |
Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis.
Topics: Aging; Animals; Blotting, Western; Cell Division; Crosses, Genetic; DNA-Binding Proteins; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Germ Cells; In Situ Hybridization; Loss of Heterozygosity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphogenesis; Ovary; Ovum; Pseudopregnancy; Stem Cells; Testis; Tetrazolium Salts; Thiazoles; Transcription Factors; Zinc Fingers | 2003 |
[Study on anticancer activity of Syngnathus in vitro].
Topics: Animals; Antineoplastic Agents; Cell Division; Fishes; HeLa Cells; Humans; K562 Cells; Materia Medica; Prohibitins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2001 |
Covalent bonding of lysine to EVAL membrane surface to improve survival of cultured cerebellar granule neurons.
Topics: Animals; Biocompatible Materials; Cell Survival; Cells, Cultured; Cerebellum; L-Lactate Dehydrogenase; Lysine; Materials Testing; Membranes, Artificial; Microscopy, Electron, Scanning; Neurons; Polyvinyls; Rats; Surface Properties; Tetrazolium Salts; Thiazoles | 2003 |
Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases.
Topics: Amyloid; Animals; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Nucleus; Cell Survival; Cells, Cultured; Colorimetry; Enzyme Activation; Humans; Insulinoma; Islet Amyloid Polypeptide; Islets of Langerhans; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2002 |
Anti-proliferative effects of 20-epi-vitamin-D3 analogue, KH1060 in human neuroblastoma: induction of RAR-beta and p21(Cip1).
Topics: Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Bromodeoxyuridine; Calcitriol; Caspase 3; Caspases; Cell Division; Cell Survival; Cholecalciferol; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Inhibitory Concentration 50; Models, Chemical; Neuroblastoma; Proto-Oncogene Proteins c-myc; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
[The influence of somatostatin 14 on the proliferation of human retroocular fibroblasts].
Topics: Cell Division; Cells, Cultured; Colorimetry; Eye; Fibroblasts; Graves Disease; Humans; Somatostatin; Tetrazolium Salts; Thiazoles | 2001 |
2,3-Dimethoxybenzo[i]phenanthridines: topoisomerase I-targeting anticancer agents.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; DNA; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indicators and Reagents; Phenanthridines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2003 |
Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Nucleus; Coloring Agents; Disease Progression; DNA-Binding Proteins; Humans; Interleukin-6; Male; Mice; Phenotype; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Blotting, Western; Cell Cycle; Cell Division; Colonic Neoplasms; Coloring Agents; DNA-Binding Proteins; Dose-Response Relationship, Drug; G1 Phase; Humans; MutS Homolog 3 Protein; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Phyllanthus urinaria triggers the apoptosis and Bcl-2 down-regulation in Lewis lung carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Lewis Lung; Caspase 3; Caspases; Cell Survival; Cyclosporine; DNA Fragmentation; Down-Regulation; Flow Cytometry; Genes, bcl-2; Mice; Phyllanthus; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
CI-1010 induced opening of the mitochondrial permeability transition pore precedes oxidative stress and apoptosis in SY5Y neuroblastoma cells.
Topics: Antioxidants; Apoptosis; Brain Neoplasms; Cell Death; Cell Survival; DNA Fragmentation; Flow Cytometry; Humans; In Situ Nick-End Labeling; Membrane Potentials; Microscopy, Electron; Mitochondria; Neuroblastoma; Nitroimidazoles; Oxidative Stress; Permeability; Photoreceptor Cells; Radiation-Sensitizing Agents; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E | 2003 |
Rhizoma acori graminei and its active principles protect PC-12 cells from the toxic effect of amyloid-beta peptide.
Topics: Allylbenzene Derivatives; Amyloid beta-Peptides; Animals; Anisoles; Calcium; Calcium Channel Blockers; Cell Death; Cell Survival; Chromatography, High Pressure Liquid; Eugenol; Humans; Oils, Volatile; PC12 Cells; Peptide Fragments; Plant Extracts; Plants, Medicinal; Rats; Tetrazolium Salts; Thiazoles | 2003 |
Organic phenyl arsonic acid compounds with potent antileukemic activity.
Topics: Antineoplastic Agents; Arsenicals; Cell Lineage; Genes, p53; Humans; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism.
Topics: Aniline Compounds; Animals; Benzylidene Compounds; Blotting, Western; Cell Division; Ceramides; Coloring Agents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Ions; Kinetics; Mice; Phospholipases; Plasmids; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sphingolipids; Sphingomyelin Phosphodiesterase; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Trypan Blue; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Type C Phospholipases | 2003 |
Cytotoxic effect of the diterpene lactone dehydrocrotonin from Croton cajucara on human promyelocytic leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Croton; Diterpenes; Diterpenes, Clerodane; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Plants, Medicinal; Tetrazolium Salts; Thiazoles | 2003 |
Protective effects of Wuyaoshunqisan against H2O2-induced apoptosis on hippocampal cell line HiB5.
Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Cell Line; Cell Survival; DNA Fragmentation; Flow Cytometry; Hippocampus; Hydrogen Peroxide; In Situ Nick-End Labeling; Indicators and Reagents; Oxidants; Plant Extracts; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2002 |
Characterization and transcriptional analysis of the mouse Chromosome 16 cytokine receptor gene cluster.
Topics: 3T3 Cells; Animals; Base Sequence; Blotting, Northern; Cell Line; Chromosome Mapping; Chromosomes; Coloring Agents; DNA, Complementary; Exons; Gene Expression Regulation; Genes, Reporter; Humans; Introns; Ligands; Luciferases; Mice; Models, Genetic; Molecular Sequence Data; Multigene Family; Receptors, Cytokine; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tissue Distribution; Transcription Factors; Transcription, Genetic; Transfection | 2003 |
Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency.
Topics: 3T3 Cells; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Chromatography, Ion Exchange; DNA; Electrochemistry; Galactose; Genetic Therapy; Hepatocytes; Humans; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Mice; Photons; Polyethyleneimine; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Endocytosis; Galactose; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Hepatocytes; Humans; Lectins; Liver; Liver Neoplasms; Mice; Mice, Inbred ICR; Polyethyleneimine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Transgenes | 2003 |
Selective killing of cancer cells by beta -lapachone: direct checkpoint activation as a strategy against cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Division; Cell Line; Cell Transformation, Neoplastic; Coloring Agents; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Flow Cytometry; Humans; Models, Biological; Naphthoquinones; Neoplasms; Retinoblastoma Protein; S Phase; Tetrazolium Salts; Thiazoles; Transcription Factors; Tumor Cells, Cultured | 2003 |
Interference in MTT cell viability assay in activated macrophage cell line.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Cytological Techniques; HeLa Cells; Humans; Macrophage Activation; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Recombinant Proteins; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 2003 |
Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases.
Topics: Animals; Apoptosis; Bisbenzimidazole; Blotting, Western; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; DNA Fragmentation; Electrophoretic Mobility Shift Assay; Fluorescent Dyes; In Vitro Techniques; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thiocarbamates; Transcription Factor AP-1 | 2003 |
Flavonoid baicalein attenuates activation-induced cell death of brain microglia.
Topics: Animals; Apoptosis; Arachidonate 12-Lipoxygenase; Blotting, Western; Caspases; Cells, Cultured; Coloring Agents; Electrophoretic Mobility Shift Assay; Flavanones; Flavonoids; Free Radical Scavengers; Indicators and Reagents; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Mice; Microglia; NF-kappa B; Nitric Oxide; Ploidies; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Trypan Blue | 2003 |
2,3,7,8-tetrachlorobenzo-p-dioxin inhibits proliferation of SK-N-SH human neuronal cells through decreased production of reactive oxygen species.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Glutathione; Humans; Hydrogen Peroxide; Lipid Peroxidation; Neurons; Oxidation-Reduction; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Superoxide Dismutase; Teratogens; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Tumor Cells, Cultured | 2002 |
New propargyl thioquinolines--synthesis, antiproliferative activity in vitro and structure-activity relationships.
Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Screening Assays, Antitumor; Erythrocytes; Humans; Quinolines; Regression Analysis; Sheep; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Titration of non-occluded baculovirus using a cell viability assay.
Topics: Baculoviridae; Cell Division; Colorimetry; Feasibility Studies; Spectrophotometry; Tetrazolium Salts; Thiazoles; Titrimetry | 2003 |
Synthesis and cytotoxicity of dihydroartemisinin ethers containing cyanoarylmethyl group.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemisia; Drug Screening Assays, Antitumor; Ethers; Flow Cytometry; G1 Phase; HT29 Cells; Humans; Leukemia L1210; Leukemia P388; Mice; Nitriles; Tetrazolium Salts; Thiazoles | 2003 |
Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Differentiation; Cell Division; Cells, Cultured; CHO Cells; Chromans; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; G2 Phase; Glutathione; Glutathione Disulfide; Mitosis; Oxidation-Reduction; Reactive Oxygen Species; Resting Phase, Cell Cycle; Resveratrol; S Phase; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2003 |
Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Benzothiazoles; Cell Survival; Chromatography, Gel; Circular Dichroism; Congo Red; Cyclization; Drug Design; Electrophoresis, Polyacrylamide Gel; Humans; Microscopy, Electron; Molecular Sequence Data; Peptide Fragments; Protein Binding; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor.
Topics: Anti-Bacterial Agents; Apoptosis; Blotting, Western; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Coloring Agents; Cyclin B; Dose-Response Relationship, Drug; Down-Regulation; Doxycycline; Drosophila Proteins; Flow Cytometry; G2 Phase; HeLa Cells; Humans; In Situ Nick-End Labeling; Mitosis; Phosphorylation; Promoter Regions, Genetic; Propidium; Protein Kinases; Protein Serine-Threonine Kinases; Tetracycline; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Trypan Blue; Tumor Suppressor Proteins | 2003 |
Effect of recombinant basic fibroblast growth factor (bFGF) on fibroblast-like cells from human rotator cuff tendon.
Topics: Cell Count; Cell Division; Cells, Cultured; Collagen Type I; Collagen Type III; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Fibroblasts; Humans; Rotator Cuff; Tendons; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents.
Topics: Active Transport, Cell Nucleus; Adenoviridae; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Division; Cell Nucleus; Cell Survival; Cysteine Endopeptidases; Cytosol; Dose-Response Relationship, Drug; Genes, Dominant; Humans; I-kappa B Proteins; Melphalan; Microscopy, Fluorescence; Multienzyme Complexes; Multiple Myeloma; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Pyrazines; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured; Ubiquitin | 2003 |
Increased resistance of tumor cells to hyperthermia mediated by integrin-linked kinase.
Topics: Adenoviridae; Animals; Apoptosis; Blotting, Western; Caspase 9; Caspases; Cell Death; Cell Line; Coloring Agents; Down-Regulation; Fever; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Plasmids; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Apoptosis; ATP-Binding Cassette Transporters; Biological Transport; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carrier Proteins; Cell Line; Cell Line, Tumor; Cell Membrane; DNA; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Doxorubicin; Drug Resistance, Neoplasm; Glutathione; GTPase-Activating Proteins; Immunoglobulin G; Immunohistochemistry; Inhibitory Concentration 50; Lung Neoplasms; Rituximab; Tetrazolium Salts; Thiazoles; Trastuzumab | 2003 |
Reversal of drug resistance mediated by hammerhead ribozyme against multidrug resistance-associated protein 1 in a human glioma cell line.
Topics: Antibiotics, Antineoplastic; Blotting, Northern; Cell Division; Cell Line, Tumor; Cell-Free System; Coloring Agents; DNA, Complementary; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Nitrosourea Compounds; Oligonucleotide Array Sequence Analysis; RNA, Catalytic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Effects of introduction of dThdPase cDNA on sensitivity to 5'-deoxy-5-fluorouridine and tumor angiogenesis.
Topics: Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Floxuridine; Genetic Vectors; Humans; Immunohistochemistry; Inhibitory Concentration 50; Neoplasm Transplantation; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Time Factors; Transfection | 2003 |
Electrochemical deposition of hydroxyapatite with vinyl acetate on titanium implants.
Topics: Adhesiveness; Alloys; Cell Division; Cells, Cultured; Coated Materials, Biocompatible; Crystallization; Durapatite; Electrochemistry; Humans; Microscopy, Electron, Scanning; Osteoblasts; Prostheses and Implants; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; Vinyl Compounds; X-Ray Diffraction | 2003 |
In vitro effect of light-cure dental adhesive on IL-6 release from LPS-stimulated and unstimulated macrophages.
Topics: Adhesives; Animals; Cell Line; Cell Survival; Cytokines; Dental Materials; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Light; Lipopolysaccharides; Macrophages; Mice; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2003 |
Cytotoxicity of liquids and powders of chemically different dental materials evaluated using dimethylthiazol diphenyltetrazolium and neutral red tests.
Topics: Animals; Cell Membrane; Coloring Agents; Fibroblasts; Glass Ionomer Cements; L Cells; Lysosomes; Materials Testing; Methacrylates; Mice; Mitochondria; Neutral Red; Powders; Resin Cements; Solutions; Tetrazolium Salts; Thiazoles | 2003 |
Antitumor effect of intratumoral administration of dendritic cell combination with vincristine chemotherapy in a murine fibrosarcoma model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Transplantation; Combined Modality Therapy; Cytokines; Dendritic Cells; Female; Fibrosarcoma; Flow Cytometry; Immunohistochemistry; Immunotherapy; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Necrosis; Phenotype; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 2003 |
Hyperthermia and tumour necrosis factor-alpha induced apoptosis via mitochondrial damage.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line; Cyclosporine; Cytochrome c Group; Cytosol; Fever; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Immunosuppressive Agents; Membranes; Mice; Mitochondria; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Line; Coloring Agents; Cytochrome c Group; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Dominant; Green Fluorescent Proteins; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Luminescent Proteins; MAP Kinase Kinase 4; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Multiple Myeloma; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
An in-vitro evaluation of lectin cytotoxicity using cell lines derived from the ocular surface.
Topics: Antineoplastic Agents; Cell Count; Cell Line; Conjunctiva; Cornea; Epithelial Cells; Formazans; Humans; Indicators and Reagents; Intestinal Absorption; Lectins; Nitroblue Tetrazolium; Tetrazolium Salts; Thiazoles | 2002 |
In vitro and in vivo transfection of melanoma cells B16-F10 mediated by cholesterol-based cationic liposomes.
Topics: Animals; Cell Survival; Cholesterol; Chromatography, Gel; DNA, Neoplasm; Female; Flow Cytometry; Gene Transfer Techniques; Genes, Reporter; Green Fluorescent Proteins; Injections, Spinal; Liposomes; Luminescent Proteins; Melanoma, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Plasmids; Tetrazolium Salts; Thiazoles; Transfection | 2002 |
Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Death; Cell Nucleus; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; In Situ Nick-End Labeling; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; NF-kappa B; Oxidative Stress; Oxygen; PC12 Cells; Peroxides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Tetrazolium Salts; Thiazoles | 2003 |
Significance of thymidylate synthase activity in renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dihydrouracil Dehydrogenase (NADP); Disease Progression; Female; Fluorouracil; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Protein Binding; Pyrimidines; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Time Factors | 2003 |
Increased apoptosis in B-chronic lymphocytic leukemia cells as a result of cyclin D3 down regulation.
Topics: Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Caenorhabditis elegans Proteins; Cell Cycle; Cell Division; Cell Line, Tumor; Coloring Agents; Cyclin D3; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Down-Regulation; Fluorescein-5-isothiocyanate; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Oligonucleotides, Antisense; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Vidarabine | 2002 |
Ex vivo drug resistance profile in childhood acute myelogenous leukemia: no drug is more effective in comparison to acute lymphoblastic leukemia.
Topics: Carboplatin; Cell Survival; Child; Cisplatin; Coloring Agents; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome; Tumor Cells, Cultured | 2002 |
Effect of leptin in proliferating and differentiated HC11 mouse mammary cells.
Topics: Animals; Caseins; Cell Differentiation; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; Dose-Response Relationship, Drug; Epithelial Cells; Female; Leptin; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Promoter Regions, Genetic; Receptors, Cell Surface; Receptors, Leptin; Recombinant Fusion Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2003 |
Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299.
Topics: Apoptosis; bcl-2-Associated X Protein; Bee Venoms; Caspases; Cell Cycle; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Genes, bcl-2; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Indoles; Isoenzymes; Lung Neoplasms; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2003 |
Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes.
Topics: Animals; Apoptosis; Cattle; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Flow Cytometry; Glucose; Isoenzymes; Mesylates; Pericytes; Protein Kinase C; Pyrroles; Retina; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2003 |
Effect of beta-amyloid on endothelial cells: lack of direct toxicity, enhancement of MTT-induced cell death and intracellular accumulation.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Cell Death; Cell Line; Endothelium; Mice; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2003 |
Induction of necrosis and DNA fragmentation during hypothermic preservation of hepatocytes in UW, HTK, and Celsior solutions.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Caspase 3; Caspases; Cell Count; Cell Culture Techniques; Cell Division; Cell Survival; Cells, Cultured; Cryopreservation; Cryoprotective Agents; Disaccharides; DNA Fragmentation; Electrolytes; Female; Glucose; Glutamates; Glutathione; Hepatocytes; Histidine; Hypothermia, Induced; Insulin; L-Lactate Dehydrogenase; Liver Diseases; Male; Mannitol; Models, Biological; Necrosis; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Tetrazolium Salts; Thiazoles; Tissue Transplantation | 2003 |
Celsior solution compared with University of Wisconsin solution (UW) and histidine-tryptophan-ketoglutarate solution (HTK) in the protection of human hepatocytes against ischemia-reperfusion injury.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Cells, Cultured; Cryopreservation; Disaccharides; Electrolytes; Glucose; Glutamates; Glutathione; Hepatocytes; Histidine; Humans; Insulin; L-Lactate Dehydrogenase; Mannitol; Organ Preservation Solutions; Oxidation-Reduction; Potassium Chloride; Procaine; Raffinose; Reperfusion Injury; Tetrazolium Salts; Thiazoles | 2003 |
In vitro photosensitisation of a murine mammary adenocarcinoma cell line with Verteporfin.
Topics: Acridine Orange; Adenocarcinoma; Animals; Apoptosis; Coloring Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fluorescent Dyes; Light; Mammary Neoplasms, Animal; Mice; Microscopy, Fluorescence; Oxygen; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Tumor Cells, Cultured; Verteporfin | 2002 |
Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Calcium; Calpain; Carrier Proteins; Caspase 3; Caspases; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Estrogens; Fura-2; Glioma; Hydrogen Peroxide; In Situ Nick-End Labeling; Ionomycin; Ionophores; Oxidative Stress; Peptide Fragments; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, Estrogen; Spectrin; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Analysis of the phenotypes of Jurkat clones with different TRAIL-sensitivities.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Arabidopsis Proteins; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Line; Cell Survival; Coloring Agents; Fatty Acid Desaturases; Flow Cytometry; Humans; Jurkat Cells; Kinetics; Membrane Glycoproteins; NF-kappa B; Phenotype; Proteins; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Retroviridae; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2003 |
Ceramide induces cell cycle arrest and upregulates p27kip in nasopharyngeal carcinoma cells.
Topics: Carcinoma; Cell Cycle; Cell Cycle Proteins; Cell Division; Ceramides; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Activation; G1 Phase; Humans; Immunoblotting; Nasopharyngeal Neoplasms; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation | 2003 |
Inhibition of NF-kappaB sensitizes A431 cells to epidermal growth factor-induced apoptosis, whereas its activation by ectopic expression of RelA confers resistance.
Topics: Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Survival; Chromones; Coloring Agents; Comet Assay; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; I-kappa B Proteins; Models, Biological; Morpholines; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Thymidine; Transcription Factor RelA; Transfection; Tumor Cells, Cultured | 2003 |
Chromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1.
Topics: Annexin A5; Apoptosis; Blotting, Northern; Blotting, Western; Cell Line; Chromium; Coloring Agents; DNA Footprinting; DNA-Binding Proteins; Down-Regulation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Membrane Proteins; Metallothionein; Metals, Heavy; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor MTF-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Zinc | 2003 |
A rapid MTT colorimetric assay to assess the proliferative index of two Indian strains of Theileria annulata.
Topics: Animals; Cattle; Cattle Diseases; Cell Division; Cell Line; Colorimetry; Coloring Agents; Formazans; India; Lymphocytes; Tetrazolium Salts; Theileria annulata; Theileriasis; Thiazoles | 2003 |
Quantitative chemical proteomics for identifying candidate drug targets.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Delivery Systems; Humans; Oligonucleotide Array Sequence Analysis; Proteomics; Sulfonamides; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Comparison of suppressive potency between azathioprine and 6-mercaptopurine against mitogen-induced blastogenesis of human peripheral blood mononuclear cells in-vitro.
Topics: Adult; Azathioprine; Cell Separation; Female; Humans; Immunosuppressive Agents; In Vitro Techniques; Lymphocyte Activation; Male; Mercaptopurine; Mitogens; Monocytes; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2003 |
Oxidative stress and bioindicators of reproductive function in pulp and paper mill effluent exposed white sucker.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Line; Dexamethasone; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Female; Glucocorticoids; Humans; Insecticides; Linuron; Luciferases; Oxidative Stress; Plasmids; Promoter Regions, Genetic; Receptors, Glucocorticoid; Sunscreening Agents; Testosterone Congeners; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Ultraviolet Rays | 2003 |
Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells.
Topics: Animals; Biological Transport; Blotting, Western; Bromodeoxyuridine; Butadienes; Cell Division; Cells, Cultured; Coloring Agents; DNA; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Histones; Inhibitory Concentration 50; Ions; Kidney; Male; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Ouabain; Phosphorylation; Protein Isoforms; Rats; Regression Analysis; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Human tumor cells are selectively inhibited by colicins.
Topics: Cell Cycle; Cell Survival; Colicins; Eukaryotic Cells; Fibroblasts; G1 Phase; Humans; Mutation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Methionine enkephalin suppresses metabolic activity of a leukemic cell line (NALM-1) and enhances CD10 expression.
Topics: Cell Line, Tumor; DNA, Complementary; Enkephalin, Methionine; Humans; Leukemia; Neprilysin; Protease Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiorphan | 2003 |
Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Coloring Agents; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flufenamic Acid; Hydrogen-Ion Concentration; Indomethacin; Intestine, Small; Intestines; Methotrexate; Phosphorylation; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Attachment of human marrow stromal cells to titanium surfaces.
Topics: Alloys; Bone Marrow Cells; Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Division; Cell Survival; Coloring Agents; Dental Alloys; Humans; Microscopy, Electron, Scanning; Nitric Acid; Plastics; Stromal Cells; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2003 |
Developmental changes in the Ca2+-regulated mitochondrial aspartate-glutamate carrier aralar1 in brain and prominent expression in the spinal cord.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Blotting, Southern; Blotting, Western; Brain; Calcium; Calcium-Binding Proteins; Cell Line; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Gene Expression Regulation, Developmental; Glutamic Acid; In Situ Hybridization; Lactic Acid; Malates; Membrane Transport Proteins; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Neuroglia; Neurons; Organic Anion Transporters; Phosphoric Monoester Hydrolases; Protein Isoforms; Proton-Translocating ATPases; Rats; Rats, Wistar; Spinal Cord; Stem Cells; Succinic Acid; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2003 |
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.
Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cell Membrane; Colforsin; Coloring Agents; Cyclic AMP; Cyclic GMP; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Fluorouracil; Genetic Vectors; Growth Inhibitors; Immunoblotting; Inhibitory Concentration 50; Insecta; Models, Biological; Nitrosamines; Nucleotides; Organophosphonates; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zalcitabine | 2003 |
Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.
Topics: Antioxidants; Apoptosis; Artifacts; Cell Division; Colorimetry; Dose-Response Relationship, Drug; Electron Transport; Formazans; Growth Inhibitors; Histocytochemistry; Humans; Indicators and Reagents; Leukemia, T-Cell; Mitochondria; NAD; NADP; Organ Specificity; Oxidation-Reduction; Resveratrol; Stilbenes; Subcellular Fractions; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Methioninase gene therapy with selenomethionine induces apoptosis in bcl-2-overproducing lung cancer cells.
Topics: Apoptosis; Bisbenzimidazole; Blotting, Western; Carbon-Sulfur Lyases; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; Cytochromes c; Cytosol; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Genetic Therapy; Humans; Lung Neoplasms; Mitochondria; Models, Biological; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Pseudomonas putida; Selenomethionine; Staurosporine; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Analysis of interleukin-1alpha (IL-1alpha) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization.
Topics: Administration, Topical; Animal Testing Alternatives; Biological Assay; Biomarkers; Coloring Agents; Culture Techniques; Epidermal Cells; Epidermis; Humans; Interleukin-1; Interleukin-8; Irritants; Predictive Value of Tests; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles | 2003 |
Involvement of apoptosis in hydrazine induced toxicity in rat primary hepatocytes.
Topics: Animals; Apoptosis; Biomarkers; Carcinogens; Coloring Agents; DNA Damage; Dose-Response Relationship, Drug; Hepatocytes; Hydrazines; L-Lactate Dehydrogenase; Male; Membrane Potentials; Mitochondria; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles | 2003 |
Pretreatment of indole-3-carbinol augments TRAIL-induced apoptosis in a prostate cancer cell line, LNCaP.
Topics: Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Death; Coloring Agents; Free Radical Scavengers; Humans; Indoles; Male; Membrane Glycoproteins; Prostatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells.
Topics: Apoptosis; Caspase 3; Caspases; Catalysis; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Enzyme Activation; G1 Phase; Humans; Keratinocytes; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Triterpenes; Trypan Blue; Tumor Suppressor Protein p53; Ursolic Acid | 2003 |
Cytoreductive effects of farnesyl transferase inhibitors on multiple myeloma tumor cells.
Topics: Alkyl and Aryl Transferases; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Farnesyltranstransferase; Flow Cytometry; Genes, ras; Humans; Interleukin-6; Mitogen-Activated Protein Kinases; Multiple Myeloma; Mutation; NF-kappa B; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2003 |
Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Cell Division; Cell Line; Cell Survival; Cloning, Molecular; Coloring Agents; DNA, Complementary; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Humans; Lysophospholipids; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Protein Isoforms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sequence Homology, Amino Acid; Signal Transduction; Sphingolipids; Sphingosine; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 2003 |
Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Cell Survival; Coloring Agents; Crystallography, X-Ray; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Fibroblast Growth Factors; Heparin; Humans; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Channels; Sulfates; Tetrazolium Salts; Thiazoles | 2003 |
Erk pathway and activator protein 1 play crucial roles in FGF2-stimulated premature cranial suture closure.
Topics: Amino Acid Motifs; Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Nucleus; Cells, Cultured; Coloring Agents; Craniosynostoses; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Humans; In Situ Hybridization; Mice; Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; Osteoblasts; Osteopontin; Promoter Regions, Genetic; RNA; RNA, Messenger; Sialoglycoproteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2003 |
Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cloning, Molecular; Coloring Agents; DNA, Complementary; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Gene Expression Regulation; Humans; Models, Biological; Neoplasms, Glandular and Epithelial; Oligonucleotides; Oligonucleotides, Antisense; Open Reading Frames; Plasmids; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins c-myc; Retinoids; Retroviridae; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Chondrocyte behaviors on poly-L-lactic acid (PLLA) membranes containing hydroxyl, amide or carboxyl groups.
Topics: Animals; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Chondrocytes; Lactic Acid; Microscopy, Atomic Force; Polyesters; Polymers; Rabbits; Tetrazolium Salts; Thiazoles | 2003 |
Biomimetic surface modification of poly(L-lactic acid) with chitosan and its effects on articular chondrocytes in vitro.
Topics: Animals; Biocompatible Materials; Bromodeoxyuridine; Cartilage, Articular; Cattle; Cell Adhesion; Cell Division; Cell Survival; Chitin; Chitosan; Chondrocytes; Collagen; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Glycosaminoglycans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Nitrogen; Polyesters; Polymers; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2003 |
Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
Topics: Animals; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Survival; Chromones; Coloring Agents; Enterovirus B, Human; Enzyme Activation; Enzyme Inhibitors; Genes, Dominant; Glycogen Synthase Kinase 3; GTP Phosphohydrolases; HeLa Cells; Humans; Mice; Morpholines; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2003 |
Requirement of gap junctional intercellular communication for human villous trophoblast differentiation.
Topics: Cell Communication; Cell Differentiation; Cells, Cultured; Chorionic Gonadotropin; Chorionic Villi; Connexin 43; Female; Flow Cytometry; Gap Junctions; Giant Cells; Heptanol; Humans; Immunoblotting; Immunohistochemistry; Pregnancy; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Trophoblasts | 2003 |
RS-4252 inhibits amyloid beta-induced cytotoxicity in HeLa cells.
Topics: Amyloid beta-Peptides; Chromans; HeLa Cells; Humans; Oxidation-Reduction; Peptide Fragments; Phenols; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; Triazines | 2003 |
Cadmium induces apoptosis in anterior pituitary cells that can be reversed by treatment with antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cadmium; Caspases; Cell Survival; Chromans; DNA Fragmentation; Free Radical Scavengers; Hormones; Immunohistochemistry; Male; Oxidative Stress; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Vitamin E | 2003 |
Effects of mineral trioxide aggregate (MTA) extracts on mitogen-activated protein kinase activity in human osteosarcoma cell line (U2OS).
Topics: Aluminum Compounds; Analysis of Variance; Apoptosis; Biocompatible Materials; Blotting, Western; Calcium Compounds; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Flavonoids; Humans; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinases; Oxides; Signal Transduction; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Synthesis and characterization of a novel degradable phosphate-containing hydrogel.
Topics: Acrylates; Biocompatible Materials; Cell Survival; Coloring Agents; Cross-Linking Reagents; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Light; Magnetic Resonance Spectroscopy; Methacrylates; Models, Chemical; Polyethylene Glycols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering; Ultraviolet Rays; Water | 2003 |
Fabrication and characterization of hydrophilic poly(lactic-co-glycolic acid)/poly(vinyl alcohol) blend cell scaffolds by melt-molding particulate-leaching method.
Topics: Animals; Cells, Cultured; Chondrocytes; Coloring Agents; Dose-Response Relationship, Drug; Glycolates; Humans; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Rabbits; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2003 |
Aromatase activity modulation by lindane and bisphenol-A in human placental JEG-3 and transfected kidney E293 cells.
Topics: Adult; Air Pollutants, Occupational; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Cell Line; DNA, Complementary; Female; Hexachlorocyclohexane; Humans; Insecticides; Kidney; Phenols; Placenta; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Effects of the mycotoxin ochratoxin A and some of its metabolites on human kidney cell lines.
Topics: Antigens, CD; Antigens, Surface; Carcinogens; CD55 Antigens; CD59 Antigens; Cell Division; Cell Line; Cell Membrane; Coloring Agents; Humans; Kidney; Membrane Cofactor Protein; Membrane Glycoproteins; Ochratoxins; Oxidation-Reduction; Propidium; Tetrazolium Salts; Thiazoles | 2003 |
3,5,6-Trisubstituted naphthostyrils as CDK2 inhibitors.
Topics: Antimetabolites; Bromodeoxyuridine; CDC2-CDC28 Kinases; Cell Cycle; Cell Line, Tumor; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indicators and Reagents; Models, Molecular; Molecular Conformation; Naphthalenes; Oxidation-Reduction; Pyrroles; Tetrazolium Salts; Thiazoles | 2003 |
Synthesis, biological evaluation and DNA binding properties of novel bleomycin analogues.
Topics: Antibiotics, Antineoplastic; Binding Sites; Bleomycin; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Chromatography, Agarose; DNA, Neoplasm; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Tetrazolium Salts; Thiazoles | 2003 |
3-nitropropionic acid inhibition of succinate dehydrogenase (complex II) activity in cultured Chinese hamster ovary cells: antagonism by L-carnitine.
Topics: Animals; Carnitine; Cell Respiration; CHO Cells; Coloring Agents; Cricetinae; Enzyme Inhibitors; Formazans; Neuroprotective Agents; Nitro Compounds; Oxidation-Reduction; Propionates; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2003 |
A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspases; Cell Death; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chromatin; Cytochromes c; Cytoplasm; Cytosol; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Models, Chemical; Neoplasm Transplantation; Nucleosomes; Poly(ADP-ribose) Polymerases; Polyamines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2003 |
Intracellular transport of plant toxins ricin and viscumin from different plasma membrane sites.
Topics: 3T3 Cells; Animals; Binding, Competitive; Biological Transport; Cell Membrane; Cell Survival; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Mice; Microscopy, Confocal; Plant Preparations; Plant Proteins; Receptors, Cell Surface; Ribosome Inactivating Proteins, Type 2; Ricin; Tetrazolium Salts; Thiazoles; Tissue Fixation; Toxins, Biological | 2003 |
Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Densitometry; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Genistein; Humans; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
Alkylphosphocholines inhibit proliferation of human retinal pigment epithelial cells.
Topics: Adolescent; Adult; Aged; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Humans; Middle Aged; Phosphorylcholine; Pigment Epithelium of Eye; Protein Kinase C; Tetrazolium Salts; Thiazoles; Trypan Blue | 2003 |
Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters.
Topics: Amino Acid Transport System X-AG; Amino Acids; Anesthetics, Intravenous; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Gangliosides; Glucose; Glutamic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Microscopy, Phase-Contrast; Neurons; Neuroprotective Agents; Oxygen; Pregnancy; Propofol; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2003 |
Fibrillar aggregates of the tumor suppressor p53 core domain.
Topics: Animals; Cell Line; Hot Temperature; Humans; Macrophages; Mice; Microscopy, Atomic Force; Microscopy, Electron; Oxidation-Reduction; Pressure; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2003 |
Pulp cell responses during hypoxia and reoxygenation in vitro.
Topics: Alkaline Phosphatase; Animals; Cell Division; Cell Hypoxia; Cell Survival; Coloring Agents; Culture Techniques; Dental Pulp; Dogs; Endothelial Growth Factors; HSP70 Heat-Shock Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Oxygen Consumption; Protein Isoforms; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
The pesticide malathion induces alterations in actin cytoskeleton and in cell adhesion of cultured breast carcinoma cells.
Topics: Actins; beta Catenin; Blotting, Western; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cholinesterase Inhibitors; Coloring Agents; Cytoskeletal Proteins; Cytoskeleton; Electrophoresis; Humans; Insecticides; Malathion; Microscopy, Fluorescence; rac1 GTP-Binding Protein; rho GTP-Binding Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators | 2003 |
Effect of FHIT gene replacement on growth, cell cycle and apoptosis in pancreatic cancer cells.
Topics: Acid Anhydride Hydrolases; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Flow Cytometry; G1 Phase; Genetic Therapy; Humans; Immunohistochemistry; Microscopy, Confocal; Neoplasm Proteins; Pancreatic Neoplasms; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Acrylic cement added with antiblastics in the treatment of bone metastases. Ultrastructural and in vitro analysis.
Topics: Antineoplastic Agents; Bone Cements; Bone Neoplasms; Cell Division; Cell Survival; Cisplatin; Coloring Agents; Doxorubicin; Drug Carriers; Humans; Methotrexate; Methylmethacrylate; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.
Topics: Acetylcysteine; Adenosine Triphosphate; Amyotrophic Lateral Sclerosis; Blotting, Western; Caspase 3; Caspases; Cell Death; DNA Fragmentation; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; L-Lactate Dehydrogenase; Mitochondria; Mutation; Neuroblastoma; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Gadd45gamma expression is reduced in anaplastic thyroid cancer and its reexpression results in apoptosis.
Topics: Adenoviridae; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Carcinoma; GADD45 Proteins; Gene Expression Regulation, Neoplastic; Genes, p53; Genetic Therapy; Humans; Immunohistochemistry; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Protein Biosynthesis; Proteins; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Transduction, Genetic; Transplantation, Heterologous; Tumor Cells, Cultured | 2003 |
IL-18 is produced by prostate cancer cells and secreted in response to interferons.
Topics: Antineoplastic Agents; Caspase 1; Caspase Inhibitors; Cell Division; Cohort Studies; DNA Primers; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Interferon-alpha; Interferon-gamma; Interleukin-18; Interleukin-18 Receptor alpha Subunit; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Interleukin; Receptors, Interleukin-18; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
The role of oxidant-mediated pathways in the cytotoxicity of endothelial cells exposed to mesenteric lymph from rats subjected to trauma-hemorrhagic shock.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Coloring Agents; Endothelial Cells; Humans; L-Lactate Dehydrogenase; Lipoxygenase; Male; Masoprocol; Mesentery; Oxidants; Rats; Rats, Sprague-Dawley; Shock; Tetrazolium Salts; Thiazoles; Time Factors; Umbilical Veins | 2003 |
Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior.
Topics: Animals; Blotting, Western; Bromodeoxyuridine; Cell Division; Cell Movement; Coloring Agents; Cricetinae; Cytoskeleton; Enzyme Activation; Extracellular Matrix; Fibronectins; Integrin alphaV; Integrin alphaVbeta3; Matrix Metalloproteinase 2; Mice; Neoplasm Invasiveness; Phenotype; Retroviridae; src-Family Kinases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitronectin | 2003 |
A requirement for calcium-independent phospholipase A2 in thrombin-induced arachidonic acid release and growth in vascular smooth muscle cells.
Topics: Animals; Arachidonic Acid; Blotting, Western; Coloring Agents; DNA; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Group VI Phospholipases A2; Imidazoles; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Naphthalenes; Oleic Acid; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Pyridines; Pyrones; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors | 2003 |
Role of N-methyl-D-aspartate receptors in the neuroprotective activation of extracellular signal-regulated kinase 1/2 by cisplatin.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain; Caspases; Cells, Cultured; Cisplatin; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Genes, Dominant; Glutamic Acid; Glycine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Neurons; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2003 |
Protective effect of Acanthopanax senticosus against ethanol-induced apoptosis of human neuroblastoma cell line SK-N-MC.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA Fragmentation; Drugs, Chinese Herbal; Eleutherococcus; Ethanol; Flow Cytometry; Humans; Neuroblastoma; Reverse Transcriptase Polymerase Chain Reaction; Solvents; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloidosis; Animals; Coloring Agents; Humans; Hydrogen Bonding; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutation; PC12 Cells; Peptide Fragments; Peptides; Protein Conformation; Protein Structure, Secondary; Rats; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes.
Topics: Apoptosis; Atractyloside; Blotting, Western; Cell Line; Cell Survival; Cells, Cultured; Ceramides; Coloring Agents; Cytochromes c; Cytoplasm; DNA; DNA-Binding Proteins; Electron Transport; Fibroblasts; Glutathione; HeLa Cells; Humans; Intercellular Adhesion Molecule-1; Keratinocytes; Mitochondria; Oxygen; Precipitin Tests; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-2; Transcription Factors | 2003 |
Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells.
Topics: Antioxidants; Bromodeoxyuridine; Catalase; Catechin; Epithelial Cells; Flavonoids; Humans; Neoplasms; Oxidative Stress; Phenols; Polymers; Reactive Oxygen Species; Superoxide Dismutase; Tea; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
Topics: Acetylcysteine; Adenoviridae; Animals; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Brain Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Gene Transfer Techniques; Genes, Tumor Suppressor; Glioblastoma; Glioma; Glutathione Transferase; Humans; Interleukins; Necrosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Microsomal prostaglandin E synthase-1 is overexpressed in head and neck squamous cell carcinoma.
Topics: Blotting, Western; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Coloring Agents; Head and Neck Neoplasms; Humans; Immunoblotting; Immunohistochemistry; Intramolecular Oxidoreductases; Microsomes; Mucous Membrane; Prognosis; Prostaglandin-E Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2).
Topics: Animals; Animals, Newborn; Antimetabolites; Apoptosis; Blotting, Western; Calcium; Calcium-Binding Proteins; Cells, Cultured; Clathrin; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Dose-Response Relationship, Drug; Endocytosis; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Humans; MAP Kinase Signaling System; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Myocardium; Myocytes, Cardiac; Oxidative Stress; Phosphorylation; Protein Binding; Protein Kinase C; S100 Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Trypan Blue; Type C Phospholipases | 2003 |
Radiation protection of HepG2 cells by Podophyllum hexandrum Royale.
Topics: Cell Cycle; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electron Transport; G2 Phase; Glutathione; Humans; Lipid Metabolism; Lipid Peroxidation; Membrane Potentials; Mitosis; Nitric Oxide; Oxidation-Reduction; Podophyllum; Radiation Protection; Radiation-Protective Agents; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
TCDD-induced apoptosis in EL-4 cells deficient of the aryl hydrocarbon receptor and down-regulation of IGFBP-6 prevented the apoptotic cell death.
Topics: Animals; Apoptosis; Blotting, Western; Deoxyribonuclease I; DNA Fragmentation; Down-Regulation; Environmental Pollutants; Insulin-Like Growth Factor Binding Protein 6; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oligoribonucleotides, Antisense; Plasmids; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
The tumor promoting effect of lime-piper betel quid in JB6 cells.
Topics: Animals; Areca; Calcium Compounds; Carcinogenicity Tests; Carcinogens; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Citrus aurantiifolia; G1 Phase; Hydrogen Peroxide; Mice; Ornithine Decarboxylase; Oxides; Peroxidase; Piper; Plant Extracts; S Phase; Tetrazolium Salts; Thiazoles | 2003 |
Overexpression of superoxide dismutase 1 protects against beta-amyloid peptide toxicity: effect of estrogen and copper chelators.
Topics: Amyloid beta-Peptides; Apoptosis; Benzimidazoles; Blotting, Western; Brain Neoplasms; Caspase 1; Caspase 3; Caspases; Cell Differentiation; Cell Line; Chelating Agents; Coloring Agents; Copper; Electrophoresis, Polyacrylamide Gel; Estradiol; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Neuroblastoma; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Acquisition of drug resistance by constitutive suppression of NF-kappaB in ras-transformed NIH3T3 mouse fibroblasts.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Camptothecin; Cell Line, Transformed; Cell Nucleus; Cell Survival; Coloring Agents; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fibroblasts; Flow Cytometry; Mice; Mitomycin; NF-kappa B; NIH 3T3 Cells; Peplomycin; Tetrazolium Salts; Thiazoles; Transfection | 2003 |
Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Humans; Neoplasms; Oncogene Proteins, Viral; Repressor Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2003 |
Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Coloring Agents; Doxorubicin; Flow Cytometry; Humans; Inhibitory Concentration 50; Microscopy, Confocal; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Oscillating perfusion of cell suspensions through three-dimensional scaffolds enhances cell seeding efficiency and uniformity.
Topics: Animals; Bioreactors; Bone Marrow Cells; Calcium Phosphates; Cartilage, Articular; Cell Adhesion; Cell Aggregation; Cell Count; Cell Culture Techniques; Cell Division; Cell Survival; Cells, Immobilized; Chondrocytes; Data Interpretation, Statistical; Humans; Hyaluronic Acid; Polyesters; Polyethylene Glycols; Rheology; Staining and Labeling; Stromal Cells; Tetrazolium Salts; Thiazoles | 2003 |
Effect of Gas6 on secretory phospholipase A(2)-IIA-induced apoptosis in cortical neurons.
Topics: Animals; Apoptosis; Benzimidazoles; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Group II Phospholipases A2; Humans; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Neurons; Phospholipases A; Pregnancy; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2003 |
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: implications for the prevention and therapeutics of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Flavonoids; Humans; Kidney; Kinetics; Microscopy, Electron; Peptide Fragments; Phenols; Polymers; Quercetin; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2003 |
Synthesis, X-ray diffraction structures, spectroscopic properties, and in vitro antitumor activity of isomeric (1H-1,2,4-triazole)Ru(III) complexes.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Organometallic Compounds; Ruthenium; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Triazoles | 2003 |
Syntheses of 2, 5-dialkylfuran and tetrahydrofuran carbinols and their cytotoxic activity.
Topics: Antineoplastic Agents; Bacteria; Drug Screening Assays, Antitumor; Furans; Humans; Indicators and Reagents; Methanol; Microbial Sensitivity Tests; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Synthesis and enzymatic transformations of 5-halo-6-methoxy-5,6-dihydro derivatives of 5-[1-methoxy-2-halo (or 2,2-dihalo)ethyl]-2'-deoxyuridines as potential herpes simplex virus inhibitors.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Chromatography, Thin Layer; Coloring Agents; Deoxyuridine; Drug Design; Escherichia coli; Magnetic Resonance Spectroscopy; Models, Chemical; Simplexvirus; Temperature; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Vero Cells | 2003 |
Activation of p53 signalling in acetylsalicylic acid-induced apoptosis in OC2 human oral cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Cycle; Cell Division; Cyclooxygenase 2; Enzyme Inhibitors; Humans; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinases; Mouth Neoplasms; Neoplasm Proteins; Nuclear Proteins; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Drug-sensitivity pattern analysis for study of functional relationship between gene products.
Topics: 3T3 Cells; Animals; DNA, Complementary; Drug Resistance; I-kappa B Kinase; I-kappa B Proteins; In Vitro Techniques; Mice; NF-KappaB Inhibitor alpha; Protein Serine-Threonine Kinases; Proteins; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Protein p53 | 2003 |
Resistance to Fas-mediated cell death in BeWo and NJG choriocarcinoma cell lines: implications in immune privilege.
Topics: Antibodies, Monoclonal; Apoptosis; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Choriocarcinoma; Coculture Techniques; Dose-Response Relationship, Immunologic; Down-Regulation; Fas Ligand Protein; fas Receptor; Female; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Membrane Glycoproteins; Pregnancy; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uterine Neoplasms | 2003 |
Enhanced antitumor activity of irofulven in combination with 5-fluorouracil and cisplatin in human colon and ovarian carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Inhibitory Concentration 50; Models, Chemical; Ovarian Neoplasms; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2003 |
p53-deficient cells display increased sensitivity to anthracyclines after loss of the catalytic subunit of the DNA-dependent protein kinase.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Catalytic Domain; Cell Line; DNA Damage; DNA Fragmentation; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibroblasts; G2 Phase; In Situ Nick-End Labeling; Inhibitory Concentration 50; Mice; Mice, Transgenic; Mitosis; Mutation; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2003 |
PC-SPES: Molecular mechanism to induce apoptosis and down-regulate expression of PSA in LNCaP human prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Nucleus; Coloring Agents; Down-Regulation; Drugs, Chinese Herbal; Genes, Dominant; Humans; Luciferases; Male; Models, Genetic; Phosphorylation; Plasmids; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Structure, Tertiary; Receptors, Androgen; Response Elements; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection | 2003 |
Induction of endogenous antioxidants and phase 2 enzymes by alpha-lipoic acid in rat cardiac H9C2 cells: protection against oxidative injury.
Topics: Animals; Antioxidants; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Models, Biological; Models, Chemical; Myocardium; Oxidative Stress; Oxygen; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thioctic Acid; Time Factors; Xanthine | 2003 |
Synthesis of a novel fluorescent poly(D,L-lactide) end-capped with 1-pyrenebutanol used for the preparation of nanoparticles.
Topics: Cell Survival; Chemical Phenomena; Chemistry, Physical; Fluorescent Dyes; Humans; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Microspheres; Molecular Weight; Monocytes; Phagocytosis; Polyesters; Pyrenes; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2003 |
Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition.
Topics: Adenoviridae; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Separation; Chloramphenicol O-Acetyltransferase; Cisplatin; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Flow Cytometry; G1 Phase; Humans; Immunohistochemistry; Inhibitory Concentration 50; Plasmids; Protein Binding; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-2; Transcription Factors; Tumor Suppressor Protein p53 | 2003 |
Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells.
Topics: Acetals; Artemisinins; Cell Division; Colorimetry; Endothelial Cells; Female; Humans; Lactones; Pregnancy; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2003 |
Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening.
Topics: Binding Sites; Computer Simulation; Databases, Genetic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Humans; K562 Cells; Leukemia, Myeloid, Acute; Models, Molecular; Molecular Conformation; Protein-Tyrosine Kinases; Tetrazolium Salts; Thiazoles | 2003 |
The total synthesis of an aurone isolated from Uvaria hamiltonii: aurones and flavones as anticancer agents.
Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Cycle; DNA, Neoplasm; Flavonoids; G2 Phase; Humans; Indicators and Reagents; K562 Cells; Mitosis; Models, Molecular; Molecular Conformation; Protein Binding; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tubulin; Uvaria | 2003 |
Flavopiridol potently induces small cell lung cancer apoptosis during S phase in a manner that involves early mitochondrial dysfunction.
Topics: Aphidicolin; Apoptosis; Blotting, Western; Carcinoma, Small Cell; Caspase 3; Caspases; Cell Division; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Membrane Potentials; Mitochondria; Piperidines; Poly(ADP-ribose) Polymerases; S Phase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2003 |
Agmatine induces glutamate release and cell death in cultured rat cerebellar granule neurons.
Topics: Agmatine; Animals; Botulinum Toxins; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Neurons; Potassium; Quinoxalines; Rats; Tetrazolium Salts; Thiazoles | 2003 |
alpha-Glycerylphosphorylethanolamine rescues astrocytes from mitochondrial impairment and oxidative stress induced by amyloid beta-peptides.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cell Membrane; Cells, Cultured; Gliosis; Lipid Peroxidation; Membrane Fluidity; Membrane Potentials; Microscopy, Confocal; Mitochondria; Nerve Degeneration; Oxidative Stress; Peptide Fragments; Phosphatidylethanolamines; Rats; Tetrazolium Salts; Thiazoles | 2004 |
Structure and potential immunological activity of a pectin from Centella asiatica (L.) Urban.
Topics: Animals; Cells, Cultured; Centella; Chromatography, High Pressure Liquid; Female; Glycosides; Lymphocyte Activation; Lymphocytes; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Oxidation-Reduction; Pectins; Tetrazolium Salts; Thiazoles | 2003 |
Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Base Sequence; beta-Galactosidase; Blotting, Western; Cell Line, Tumor; Coloring Agents; Gene Expression Regulation; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; HeLa Cells; Humans; Lac Operon; Mice; Mice, Nude; Models, Genetic; Molecular Sequence Data; Neoplasm Transplantation; Neoplasms, Experimental; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc; Sp1 Transcription Factor; Telomerase; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Up-Regulation | 2003 |
Prevention of ornithine cytotoxicity by nonpolar side chain amino acids in retinal pigment epithelial cells.
Topics: Amino Acid Transport System y+; Amino Acids; Amino Acids, Cyclic; Cell Survival; Cells, Cultured; Colorimetry; Cytoprotection; Fusion Regulatory Protein 1, Heavy Chain; Fusion Regulatory Protein 1, Light Chains; Gyrate Atrophy; Humans; Large Neutral Amino Acid-Transporter 1; Ornithine; Ornithine-Oxo-Acid Transaminase; Pigment Epithelium of Eye; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2003 |
Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B.
Topics: Annexin A5; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatin; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Deoxycytidine; Detergents; Docetaxel; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Epothilones; Flow Cytometry; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Multienzyme Complexes; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Sepharose; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab | 2003 |
Influence of cryoprotective agent and cooling rate on frozen and thawed hemocytes from the Mollusk Haliotis tuberculata.
Topics: Animals; Cell Survival; Cold Temperature; Coloring Agents; Cryopreservation; Cryoprotective Agents; DNA; Freezing; Hemocytes; Mollusca; Osmotic Pressure; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Coloring Agents; DNA-Binding Proteins; Docetaxel; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Transplantation; Oligonucleotides, Antisense; Phosphotyrosine; Signal Transduction; STAT3 Transcription Factor; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Vascular Endothelial Growth Factor A | 2003 |
Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice.
Topics: Amino Acids; Animals; Blotting, Western; Bone and Bones; Bone Density; Cell Division; Coloring Agents; Cytomegalovirus; DNA, Complementary; Dose-Response Relationship, Drug; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Mice; Mice, Transgenic; Osteoblasts; Osteocalcin; Phenotype; Phosphoglycerate Kinase; Promoter Regions, Genetic; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
In vitro study of osteogenic differentiation of bone marrow stromal cells on heat-treated porcine trabecular bone blocks.
Topics: Animals; Bone and Bones; Bone Marrow Cells; Bone Substitutes; Cattle; Cell Differentiation; Cell Division; Collagen; Durapatite; Hot Temperature; Humans; In Vitro Techniques; Microscopy, Electron; Microscopy, Electron, Scanning; Osteoblasts; Rabbits; Stromal Cells; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transplantation; X-Ray Diffraction | 2004 |
In vitro cytotoxicity of traditional versus contemporary dental ceramics.
Topics: Aluminum Silicates; Analysis of Variance; Animals; BALB 3T3 Cells; Biocompatible Materials; Ceramics; Coloring Agents; Dental Materials; Dental Polishing; Dental Porcelain; Lithium Compounds; Matched-Pair Analysis; Materials Testing; Mice; Mitochondria; Polytetrafluoroethylene; Potassium Compounds; Succinate Dehydrogenase; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
A neocartilage ideal for extracellular matrix macromolecule immunolocalization.
Topics: Aggrecans; Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagen Type I; Collagen Type II; Collagenases; Coloring Agents; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Lectins, C-Type; Matrix Metalloproteinase 13; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Swine; Tetrazolium Salts; Thiazoles | 2003 |
Synergistic protection of PC12 cells from beta-amyloid toxicity by resveratrol and catechin.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Cell Count; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Lipid Peroxidation; PC12 Cells; Peptide Fragments; Rats; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Thiobarbiturates | 2003 |
The effect of mycophenolate acid on hepatitis B virus replication in vitro.
Topics: Cell Line; Coloring Agents; DNA, Viral; Enzyme Inhibitors; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; In Vitro Techniques; Mycophenolic Acid; Tetrazolium Salts; Thiazoles; Virus Replication | 2003 |
Cell-based quantitative evaluation of the MTT assay.
Topics: Animals; Coloring Agents; Connective Tissue Cells; Cricetinae; Cytodiagnosis; Cytological Techniques; Diagnostic Imaging; Endosomes; Fibroblasts; Image Processing, Computer-Assisted; Macrophages, Alveolar; Mice; Mice, Inbred Strains; Microscopy, Confocal; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2003 |
Evaluation of cytotoxicity of MTAD using the MTT-tetrazolium method.
Topics: Animals; Calcium Hydroxide; Cell Division; Cetrimonium Compounds; Chlorhexidine; Citric Acid; Coloring Agents; Doxycycline; Edetic Acid; L Cells; Mice; Polysorbates; Root Canal Irrigants; Smear Layer; Sodium Hypochlorite; Tetrazolium Salts; Thiazoles | 2003 |
Ruthenium(II) sulfoxide-maltolato and -nitroimidazole complexes: synthesis and MTT assay.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Nitroimidazoles; Organometallic Compounds; Pyrones; Ruthenium; Stereoisomerism; Sulfoxides; Tetrazolium Salts; Thiazoles | 2003 |
Triphenyl tin benzimidazolethiol, a novel antitumor agent, induces mitochondrial-mediated apoptosis in human cervical cancer cells via suppression of HPV-18 encoded E6.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Benzimidazoles; Caspases; Cell Line, Tumor; Cell Separation; DNA; Down-Regulation; Female; Flow Cytometry; Fluorescent Dyes; G1 Phase; HeLa Cells; Humans; Membrane Proteins; Mitochondria; Models, Chemical; Oligonucleotides; Organotin Compounds; Poly(ADP-ribose) Polymerases; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation; Uterine Cervical Neoplasms | 2003 |
Chemopreventive allylthiopyridazines inhibit invasion, migration and angiogenesis in hepatocarcinoma cells.
Topics: Anticarcinogenic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Chemical; Neoplasm Invasiveness; Neovascularization, Pathologic; Pyridazines; Tetrazolium Salts; Thiazoles; Time Factors; Umbilical Veins; Wound Healing | 2003 |
Stimulation of CD40 inhibits Fas- or chemotherapy-mediated apoptosis and increases cell motility in human gastric carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma; CD40 Antigens; CD40 Ligand; Cell Division; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; fas Receptor; Flow Cytometry; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2003 |
The PLC-PKC cascade is required for IL-1beta-dependent Erk and Akt activation: their role in proliferation.
Topics: Animals; Antigens, Differentiation; BALB 3T3 Cells; Cell Division; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Glycoproteins; Immunoblotting; Indoles; Interleukin-1; Maleimides; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neural Cell Adhesion Molecule L1; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Type C Phospholipases | 2003 |
Heat-induced reformulation of amphotericin B-deoxycholate favours drug uptake by the macrophage-like cell line J774.
Topics: Algorithms; Amphotericin B; Animals; Antifungal Agents; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Deoxycholic Acid; Drug Combinations; Hot Temperature; L-Lactate Dehydrogenase; Lipoproteins, LDL; LLC-PK1 Cells; Macrophages; Mice; Swine; Tetrazolium Salts; Thiazoles | 2003 |
Hexarelin protects rat cardiomyocytes from angiotensin II-induced apoptosis in vitro.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; Growth Substances; In Situ Nick-End Labeling; Myocytes, Cardiac; Oligopeptides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles; Vasoconstrictor Agents | 2004 |
Effects of phenformin on the proliferation of human tumor cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Culture Media; Glucose; Humans; Hypoglycemic Agents; Male; Neuroblastoma; Oncogene Protein p21(ras); Phenformin; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles | 2003 |
Toxicity and apoptosis induced by the mycotoxins nivalenol, deoxynivalenol and fumonisin B1 in a human erythroleukemia cell line.
Topics: Apoptosis; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Division; Cell Membrane; Cell Physiological Phenomena; Cell Survival; Cycloheximide; DNA Replication; Dose-Response Relationship, Drug; Flow Cytometry; Fumonisins; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Mitochondria; Mycotoxins; Tetrazolium Salts; Thiazoles; Trichothecenes; Trypan Blue | 2004 |
Effects of growth/differentiation factor-5 on human periodontal ligament cells.
Topics: Actins; Alkaline Phosphatase; Biomarkers; Bone Morphogenetic Proteins; Cell Division; Cells, Cultured; Collagen Type I; Coloring Agents; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycosaminoglycans; Growth Differentiation Factor 5; Humans; Periodontal Ligament; Receptors, Growth Factor; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 2003 |
Cell sensitivity assays: the MTT assay.
Topics: Animals; Cell Division; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Drug Evaluation, Preclinical; Drug Resistance; Humans; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Cell Count; Cell Line; DNA; Dopamine Agents; Dopamine Agonists; Humans; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrazolium Salts; Thiazoles | 2003 |
Interleukin-10 receptor signaling through STAT-3 regulates the apoptosis of retinal ganglion cells in response to stress.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cytoprotection; Dexamethasone; DNA-Binding Proteins; Flow Cytometry; Glucocorticoids; Immunohistochemistry; Insulin-Like Growth Factor I; Interleukin-10; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Interleukin; Receptors, Interleukin-10; Retinal Ganglion Cells; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Trans-Activators | 2003 |
An in vitro model to optimize dose scheduling of multimodal radioimmunotherapy and chemotherapy: effects of p53 expression.
Topics: Antineoplastic Agents; Carboplatin; Cell Division; Combined Modality Therapy; Dose-Response Relationship, Drug; Doxorubicin; Drug Antagonism; Drug Resistance, Neoplasm; Drug Synergism; Female; Genetic Therapy; Humans; In Vitro Techniques; Mutation; Ovarian Neoplasms; Paclitaxel; Radioimmunotherapy; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Yttrium Radioisotopes | 2004 |
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.
Topics: Adenine; Allopurinol; Animals; Antioxidants; Apoptosis; Arachidonic Acids; Benzoquinones; Blotting, Western; Calcium; Carbon; Caspase 3; Caspases; Cell Death; Cell Survival; Chick Embryo; Chromans; Coloring Agents; Cytosol; DNA Fragmentation; Enzyme Inhibitors; Glutathione; In Situ Nick-End Labeling; Indazoles; Metalloporphyrins; Mitochondria; Neurons; Nitric Oxide Synthase; Oligomycins; Protein Isoforms; Reactive Oxygen Species; Retina; Rotenone; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors; Ubiquinone; Uncoupling Agents; Xanthine Oxidase | 2003 |
FasL-induced downregulation of CD28 expression on jurkat cells in vitro is associated with activation of caspases.
Topics: 5' Untranslated Regions; Aging; Annexins; Apoptosis; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; CD8 Antigens; Cellular Senescence; Cloning, Molecular; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Fas Ligand Protein; Genes, Reporter; Humans; In Vitro Techniques; Jurkat Cells; Luciferases; Membrane Glycoproteins; Models, Biological; Plasmids; Promoter Regions, Genetic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transcription, Genetic | 2003 |
Heat shock protects PC12 cells against MPP+ toxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Blotting, Western; Cell Death; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Fluorescent Dyes; Heat-Shock Proteins; Hot Temperature; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; MPTP Poisoning; Neoplasm Proteins; Oligopeptides; PC12 Cells; Rats; Shock; Tetrazolium Salts; Thiazoles | 2003 |
Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Coloring Agents; Cyclin D1; Cyclin D3; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dimerization; DNA; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Flow Cytometry; G1 Phase; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Ligands; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Peptides; Poly(ADP-ribose) Polymerases; Proteins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors; TNF Receptor-Associated Factor 6; Tumor Suppressor Proteins | 2004 |
Protective effect of aqueous extract of Ginseng radix against 1-methyl-4-phenylpyridinium-induced apoptosis in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Shape; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Genes, p53; Neurons; Panax; PC12 Cells; Plant Extracts; Plant Roots; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Water | 2003 |
Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells.
Topics: Amides; Amlodipine; Animals; Antipyrine; Arteriosclerosis; Basilar Artery; Cell Division; Cell Survival; Cells, Cultured; Drug Synergism; Drug Therapy, Combination; Edaravone; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Indoles; Maleimides; Methacrylates; Muscle, Smooth, Vascular; Pyridines; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2003 |
Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Angiopoietin-1; Animals; Binding Sites; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Coloring Agents; COS Cells; Endothelial Cells; Endothelium, Vascular; Genes, Dominant; Glutathione Transferase; Humans; Immunoblotting; Ligands; MAP Kinase Signaling System; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; Receptor, TIE-2; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Immunomodulatory and cytoprotective role of RP-1 in gamma-irradiated mice.
Topics: Animals; Antioxidants; Apoptosis; Bone Marrow Cells; Cell Division; Cells, Cultured; Chromatography, High Pressure Liquid; Coloring Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; G2 Phase; Gamma Rays; Macrophages; Macrophages, Peritoneal; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Plant Extracts; Podophyllum; Radiation Injuries, Experimental; Radiation-Protective Agents; S Phase; Spleen; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Commitment to apoptosis by ceramides depends on mitochondrial respiratory function, cytochrome c release and caspase-3 activation in Hep-G2 cells.
Topics: Apoptosis; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Ceramides; Coloring Agents; Cytochromes c; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Electron Transport; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flow Cytometry; Humans; Microscopy, Fluorescence; Mitochondria; Reactive Oxygen Species; Sphingosine; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Sensitization to the cytotoxicity of cisplatin by transfection with nucleotide excision repair gene xeroderma pigmentosun group A antisense RNA in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Blotting, Northern; Cell Division; Cisplatin; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Humans; Luciferases; Lung Neoplasms; Plasmids; RNA, Antisense; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein | 2003 |
Attachment of periodontal ligament cells to chlorhexidine-loaded guided tissue regeneration membranes.
Topics: Absorbable Implants; Aggregatibacter actinomycetemcomitans; Analysis of Variance; Anti-Infective Agents, Local; Cell Adhesion; Cell Survival; Cells, Cultured; Chlorhexidine; Collagen; Coloring Agents; Equipment Design; Guided Tissue Regeneration, Periodontal; Humans; Membranes, Artificial; Microscopy, Electron, Scanning; Periodontal Ligament; Polyglactin 910; Polytetrafluoroethylene; Surface Properties; Tetrazolium Salts; Thiazoles | 2003 |
Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2).
Topics: Animals; Arsenates; Arsenic; Arsenites; Cell Line; Chromatography, High Pressure Liquid; Coloring Agents; Cricetinae; Culture Media; Cytosol; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Kidney Tubules; L-Lactate Dehydrogenase; Mitochondria; Rabbits; Sodium Compounds; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2003 |
Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.
Topics: Animals; Apoptosis; Cell Death; Cell Line; Cell Line, Tumor; Cell Separation; DNA; DNA Damage; DNA Fragmentation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Flow Cytometry; Genotype; Guanine; HeLa Cells; Humans; Hydrogen Peroxide; Immunoblotting; Mice; Saccharomyces cerevisiae; Tetrazolium Salts; Thiazoles | 2004 |
The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells.
Topics: Animals; Animals, Newborn; Anti-HIV Agents; Benzimidazoles; Benzylamines; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cerebellum; Cyclams; Dizocilpine Maleate; Drug Interactions; Enzyme Activation; Glutamic Acid; Heterocyclic Compounds; HIV Envelope Protein gp120; Immunohistochemistry; Interleukin-10; Neurons; Neuroprotective Agents; Neurotoxins; Propidium; Rats; Rats, Sprague-Dawley; Receptors, CXCR4; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Evaluation for safety of cultured corneal fibroblasts with cotreatment of alcohol and mitomycin C.
Topics: Animals; Annexin A5; Apoptosis; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cornea; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Ethanol; Fibroblasts; Mitomycin; Rabbits; Safety; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Chlorpyrifos; Embryo, Mammalian; Female; Herbicides; Immunohistochemistry; Insecticides; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Pregnancy; Proto-Oncogene Proteins c-jun; Pyridones; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
An improved microtiter assay for evaluating anti-HIV-1 neutralizing antibodies from sera or plasma.
Topics: AIDS Serodiagnosis; Cell Division; HIV Antibodies; HIV Core Protein p24; HIV-1; Humans; Neutralization Tests; Tetrazolium Salts; Thiazoles | 2003 |
3-OH flavone inhibition of epidermal growth factor-induced proliferaton through blocking prostaglandin E2 production.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cell Division; Colony-Forming Units Assay; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Anti-osteoactivin antibody inhibits osteoblast differentiation and function in vitro.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Antibodies; Blotting, Western; Bone and Bones; Calcium; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Computational Biology; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Glycosylation; Membrane Glycoproteins; Microscopy, Fluorescence; Open Reading Frames; Osteoblasts; Osteocalcin; Protein Sorting Signals; Proteins; Rats; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2003 |
Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells.
Topics: Amyloid; Amyloid beta-Peptides; Cell Differentiation; Cell Line, Tumor; Coloring Agents; Cytological Techniques; Humans; Islet Amyloid Polypeptide; Neuroblastoma; Peptide Fragments; Prions; Tetrazolium Salts; Thiazoles | 2003 |
Resin composite monomers alter MTT and LDH activity of human gingival fibroblasts in vitro.
Topics: Analysis of Variance; Cells, Cultured; Coloring Agents; Composite Resins; Fibroblasts; Gingiva; Humans; L-Lactate Dehydrogenase; Membrane Lipids; Methylmethacrylates; Mitochondria; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2004 |
Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F.
Topics: Anilino Naphthalenesulfonates; Animals; Apoproteins; Benzothiazoles; Cell Membrane; Cell Nucleus; Circular Dichroism; Coloring Agents; Cytoskeleton; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Mice; Microscopy, Electron; Mutation; Myoglobin; NIH 3T3 Cells; Phalloidine; Propidium; Protein Structure, Secondary; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2004 |
Protective effects of green tea polyphenol against reactive oxygen species-induced oxidative stress in cultured rat calvarial osteoblast.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Endoplasmic Reticulum, Rough; Flavonoids; Flow Cytometry; Hydrogen Peroxide; Microscopy, Electron; Osteoblasts; Oxidative Stress; Phenols; Polyphenols; Propidium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Xanthine Oxidase | 2003 |
Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype.
Topics: Animals; Bronchodilator Agents; Cattle; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isometric Contraction; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Organ Culture Techniques; Phenotype; Potassium Chloride; Protein Serine-Threonine Kinases; rho-Associated Kinases; Tetrazolium Salts; Thiazoles; Thymidine; Trachea | 2004 |
The Oriental medicine "Cool-Cool (Cool-X-A)" inhibits inflammatory cytokine production and migration in mast cells.
Topics: Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Cytokines; Depression, Chemical; Drugs, Chinese Herbal; Humans; Interleukin-8; Mast Cells; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2004 |
Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 beta-estradiol-mediated neuroprotection.
Topics: Animals; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Cells, Cultured; Chromones; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Electroretinography; Enzyme Inhibitors; Estradiol; Eye Proteins; Glutathione Transferase; Hippocalcin; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; Insulin; Light; Lipoproteins; Morpholines; Nerve Tissue Proteins; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Progesterone; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Recoverin; Retina; Signal Transduction; src Homology Domains; Tamoxifen; Tetrazolium Salts; Thiazoles | 2004 |
Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
Topics: Active Transport, Cell Nucleus; Alkaline Phosphatase; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell-Free System; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; In Situ Nick-End Labeling; Interleukin-1; Lipopolysaccharides; Microscopy, Phase-Contrast; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Peptide Fragments; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor RelA; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
Significance of COX-2 expression in human renal cell carcinoma cell lines.
Topics: Animals; Apoptosis; Blotting, Western; Butyrates; Carcinoma, Renal Cell; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclooxygenase 2; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Genetic Vectors; Humans; Immunohistochemistry; Inhibitory Concentration 50; Isoenzymes; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Nitrobenzenes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2004 |
Evaluation of combined gene regulatory elements for transcriptional targeting of suicide gene expression to malignant melanoma.
Topics: Animals; Cell Death; Cell Line; Cell Line, Tumor; Chloramphenicol O-Acetyltransferase; Coloring Agents; Cytomegalovirus; DNA; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Genes, Regulator; Genes, Reporter; Genetic Therapy; HeLa Cells; Humans; Melanoma; Mice; Neoplasm Metastasis; Plasmids; Promoter Regions, Genetic; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection | 2003 |
Cyclin A correlates with the sensitivity of human cancer cells to cytotoxic effects of 5-FU.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Collagen; Colonic Neoplasms; Coloring Agents; Cyclin A; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Humans; Immunoblotting; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S Phase; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Enhanced chemosensitivity of bladder cancer cells to cisplatin by suppression of clusterin in vitro.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Survival; Cisplatin; Clusterin; Coloring Agents; DNA Fragmentation; Glycoproteins; Humans; In Vitro Techniques; Molecular Chaperones; Oligonucleotides, Antisense; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Urinary Bladder Neoplasms | 2004 |
C2-ceramide as a cell death inducer in HC11 mouse mammary epithelial cells.
Topics: Animals; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Cells, Cultured; Ceramides; Coloring Agents; Epithelial Cells; Humans; Mammary Glands, Animal; Mice; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Cell Survival; Culture Media; Glutathione Transferase; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Neoplasms; Malondialdehyde; Materia Medica; Plant Extracts; Tetrazolium Salts; Thiazoles; Thymidine | 2003 |
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
Topics: Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Camptothecin; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Male; Metalloporphyrins; Mice; Mitomycin; Neoplasms; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Polyethylene Glycols; Proline; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing.
Topics: Animals; Blotting, Southern; Blotting, Western; Brain; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genetic Therapy; Glioma; Humans; Kinetics; Parvoviridae Infections; Parvovirus; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Virus Replication | 2004 |
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine | 2004 |
Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.
Topics: Animals; Binding, Competitive; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Membrane; Coloring Agents; Culture Media, Conditioned; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Matrix; Fibrinolysin; Flow Cytometry; Genome; Humans; Membrane Glycoproteins; Mice; Neoplasm Invasiveness; Neoplasm Transplantation; Oligonucleotides, Antisense; Peritoneal Neoplasms; Protein Binding; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Recombinant Proteins; Serine Endopeptidases; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Trypsin Inhibitor, Kunitz Soybean; Urokinase-Type Plasminogen Activator | 2004 |
Mechanisms of beta cell death during restricted and unrestricted enterovirus infection.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Cells, Cultured; Culture Techniques; Enterovirus B, Human; Enterovirus Infections; Guanidine; Insulin; Islets of Langerhans; Necrosis; Swine; Tetrazolium Salts; Thiazoles; Virus Replication | 2004 |
In vitro evaluation of the anti-prionic activity of newly synthesized congo red derivatives.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Congo Red; Cricetinae; Endopeptidases; Flow Cytometry; Fluorescent Antibody Technique; Mesocricetus; Mice; Microscopy, Electron; Molecular Sequence Data; Neuroblastoma; Peptide Fragments; Prion Diseases; Prions; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain; Catalase; Catecholamines; Cell Count; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Female; Fluoresceins; Imidazolines; Intracellular Space; Isoenzymes; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Pregnancy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Calcium; Caspase 3; Caspases; Cell Survival; Cells, Cultured; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Free Radicals; Hippocampus; Mecamylamine; Mitochondria; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Coloring Agents; Doxorubicin; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ionophores; Ions; Lipid Metabolism; Liposomes; Manganese; Manganese Compounds; Mice; Mice, SCID; Neoplasm Transplantation; Protons; Sulfates; Tetrazolium Salts; Thiazoles; Time Factors; Vincristine | 2004 |
In vitro antitumor structure-activity relationships of threo/trans/threo mono-tetrahydrofuranic acetogenins: correlations with their inhibition of mitochondrial complex I.
Topics: Acetogenins; Antineoplastic Agents; Cell Line, Tumor; Electron Transport Complex I; Fatty Alcohols; Furans; Humans; Inhibitory Concentration 50; Lactones; Molecular Structure; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2003 |
Chemotherapeutic potential of plant alkaloids and multidrug resistance mechanisms in malignant fibrous histiocytoma of the heart.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Separation; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Heart Neoplasms; Histiocytoma, Benign Fibrous; Humans; Inhibitory Concentration 50; Paclitaxel; Phenotype; Plant Extracts; Soft Tissue Neoplasms; Tetrazolium Salts; Thiazoles; Vault Ribonucleoprotein Particles; Vincristine | 2004 |
Beneficial effect of cepharanthine on overcoming drug-resistance of hepatocellular carcinoma.
Topics: Adenosine Triphosphatases; Aged; Alkaloids; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Immunohistochemistry; Inhibitory Concentration 50; Kinetics; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Depsipeptides; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G1 Phase; G2 Phase; Histone Deacetylase Inhibitors; Histones; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Microtubule-Associated Proteins; Neoplasm Proteins; Pancreatic Neoplasms; Peptides, Cyclic; Phosphatidylserines; Propidium; Survivin; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
A three amino acid peptide, Gly-Pro-Arg, protects and rescues cell death induced by amyloid beta-peptide.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Dipeptides; Enzyme Activation; Hippocampus; Immunohistochemistry; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Oligopeptides; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2003 |
RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.
Topics: Amino Acid Motifs; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autoantigens; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Chromatin; Chromatography, Affinity; Coloring Agents; DEAD-box RNA Helicases; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Electroporation; HL-60 Cells; Humans; Luciferases; Mass Spectrometry; Neoplasm Proteins; Phenotype; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Isoforms; Protein Processing, Post-Translational; RNA; RNA Helicases; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transcription Factors; Transcriptional Activation; Up-Regulation | 2004 |
Cytotoxicity of composite resins polymerized with different curing methods.
Topics: Analysis of Variance; Animals; Cell Survival; Coloring Agents; Composite Resins; Dental Equipment; L Cells; Light; Mice; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Improved therapeutic responses in a xenograft model of human B lymphoma (Namalwa) for liposomal vincristine versus liposomal doxorubicin targeted via anti-CD19 IgG2a or Fab' fragments.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antigens, CD19; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Immunoglobulin Fragments; Immunoglobulin G; Inhibitory Concentration 50; Liposomes; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; Mice, SCID; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Time Factors; Vincristine | 2004 |
Nitric oxide-induced apoptosis is mediated by Bax/Bcl-2 gene expression, transition of cytochrome c, and activation of caspase-3 in rat vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Cytochromes c; Cytoplasm; Enzyme Activation; Flow Cytometry; Gene Expression; Genes, bcl-2; In Situ Nick-End Labeling; Male; Mitochondria, Muscle; Muscle, Smooth, Vascular; Nitric Oxide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2004 |
Comparative preclinical pharmacokinetic and metabolic studies of the combretastatin prodrugs combretastatin A4 phosphate and A1 phosphate.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; Bibenzyls; Calibration; Cell Line, Tumor; Chromatography; Chromatography, High Pressure Liquid; Coloring Agents; Female; Humans; Inhibitory Concentration 50; Mass Spectrometry; Mice; Models, Chemical; Phosphorylation; Prodrugs; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
RWJ-241947 (MCC-555), a unique peroxisome proliferator-activated receptor-gamma ligand with antitumor activity against human prostate cancer in vitro and in beige/nude/ X-linked immunodeficient mice and enhancement of apoptosis in myeloma cells induced by
Topics: Agar; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Caspases; CD36 Antigens; Cell Cycle; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Survival; Genetic Linkage; Humans; Immunologic Deficiency Syndromes; Ligands; Luciferases; Male; Mice; Multiple Myeloma; Oxides; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transfection; U937 Cells; X Chromosome | 2004 |
Miltefosine induces apoptosis-like death in Leishmania donovani promastigotes.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Cell Cycle; Chromatography, Agarose; Colorimetry; DNA Fragmentation; Flow Cytometry; Leishmania donovani; Phosphatidylserines; Phosphorylcholine; Protease Inhibitors; Tetrazolium Salts; Thiazoles | 2004 |
Regulation of transglutaminase activity in articular chondrocytes through thrombin receptor-mediated factor XIII synthesis.
Topics: Animals; Arthritis; Cartilage; Chondrocytes; Coloring Agents; Dose-Response Relationship, Drug; Ethylmaleimide; Factor XIII; Factor XIIIa; Hirudins; Lyases; Proteoglycans; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors; Transglutaminases | 2004 |
Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.
Topics: Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Survival; Coloring Agents; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Endopeptidases; Enzyme Inhibitors; Etoposide; Gamma Rays; Humans; Mass Spectrometry; Models, Biological; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation | 2004 |
Behaviour of the new asbestos amphibole fluor-edenite in different lung cell systems.
Topics: Animals; Asbestos, Amphibole; Asbestos, Crocidolite; Cell Line; Cells, Cultured; Comet Assay; Cytotoxicity Tests, Immunologic; DNA; Epithelial Cells; Fibroblasts; Humans; Lung; Macrophages; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Cyclin E deregulation alters the biologic properties of ovarian cancer cells.
Topics: Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Coloring Agents; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Lovastatin; Ovarian Neoplasms; Precipitin Tests; S Phase; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Suppressor Proteins | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; Coloring Agents; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Globins; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Polymerase Chain Reaction; Pyrrolidines; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Thymine; Trifluridine; Uracil | 2004 |
Drug-induced apoptosis by a matrix metalloproteinase inhibitor, SI-27 on human malignant glioma cell lines; in vitro study.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Inhibitors; Flow Cytometry; Glioma; Humans; Matrix Metalloproteinase Inhibitors; Microscopy, Electron; Oligopeptides; Tetrazolium Salts; Thiazoles | 2004 |
Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L.
Topics: Antioxidants; Biphenyl Compounds; Cell Line; Cell Survival; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase Inhibitors; Picrates; Plant Leaves; Protease Inhibitors; Superoxides; Tetrazolium Salts; Thiazoles; Ultraviolet Rays; Zosteraceae | 2004 |
Validation of the anthrax lethal toxin neutralization assay.
Topics: Animals; Anthrax Vaccines; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Cell Division; Cell Line; Humans; Immunoassay; In Vitro Techniques; Mice; Neutralization Tests; Rabbits; Reproducibility of Results; Sensitivity and Specificity; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Mitogenic activity of Cratylia mollis lectin on human lymphocytes.
Topics: Binding Sites; Carbohydrates; Cell Division; Coloring Agents; Concanavalin A; Dose-Response Relationship, Drug; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Plants; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Adult human olfactory neural progenitors cultured in defined medium.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cell Culture Techniques; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Insulin; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Mitosis; Nerve Growth Factors; Nerve Tissue Proteins; Nestin; Neurons; Olfactory Mucosa; Ornithine Decarboxylase; Peripherins; Progesterone; Putrescine; Sodium Selenite; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Transferrin; Tubulin | 2004 |
Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Northern; Cell Line, Tumor; Clusterin; Coloring Agents; Deoxycytidine; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Gemcitabine; Glycoproteins; Humans; Immunohistochemistry; In Vitro Techniques; Lung Neoplasms; Mice; Molecular Chaperones; Nucleotides; Oligonucleotide Array Sequence Analysis; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Double-Stranded; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Activin inhibits pituitary prolactin expression and cell growth through Smads, Pit-1 and menin.
Topics: Activins; Animals; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; CHO Cells; Coloring Agents; Cricetinae; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation; Genes, Reporter; Humans; Mutagenesis; Oligonucleotides, Antisense; Pituitary Gland; Prolactin; Promoter Regions, Genetic; Protein Structure, Tertiary; Proto-Oncogene Proteins; Rats; RNA, Messenger; RNA, Small Interfering; Smad Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic; Transfection | 2004 |
Natural killer cell activity and anti-tumour effects of dehydrocrotonin and its synthetic derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Cell Survival; Croton; Diterpenes, Clerodane; Immune System; Killer Cells, Natural; Male; Mice; Mice, Inbred BALB C; Phosphoric Monoester Hydrolases; Spleen; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles | 2004 |
Saucernetin-7 isolated from Saururus chinensis inhibits proliferation of human promyelocytic HL-60 leukemia cells via G0/G1 phase arrest and induction of differentiation.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Blotting, Western; CDC2-CDC28 Kinases; Cell Adhesion Molecules; Cell Cycle; Cell Differentiation; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Furans; G1 Phase; Glutathione Transferase; GPI-Linked Proteins; HL-60 Cells; Humans; Inhibitory Concentration 50; Lignans; Lipopolysaccharide Receptors; Mice; Models, Chemical; Phagocytosis; Phosphorylation; Plant Extracts; Precipitin Tests; Resting Phase, Cell Cycle; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Saururaceae; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic | 2004 |
Effects of human pharmaceuticals on cytotoxicity, EROD activity and ROS production in fish hepatocytes.
Topics: Animals; Cell Line; Cell Separation; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Hepatocytes; Humans; Oncorhynchus mykiss; Pharmaceutical Preparations; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 2004 |
Potent protecting effects of Catuaba (Anemopaegma mirandum) extracts against hydroperoxide-induced cytotoxicity.
Topics: Animals; Antioxidants; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cell Survival; Cinchona Alkaloids; Humans; Hydro-Lyases; Interleukin-2; Interleukin-4; Plant Extracts; Plants, Medicinal; Rats; Squalene; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2004 |
Tumor necrosis factor-alpha related gene response to Epothilone B in ovarian cancer.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Epothilones; Female; Flow Cytometry; Fluorescent Antibody Technique; G2 Phase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Metallothionein; Mitosis; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
Efficacy, safety, and plasma pharmacokinetics of escalating dosages of intravenously administered ravuconazole lysine phosphoester for treatment of experimental pulmonary aspergillosis in persistently neutropenic rabbits.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Dose-Response Relationship, Drug; Female; Galactose; Half-Life; Image Processing, Computer-Assisted; Immunosuppressive Agents; Injections, Intravenous; Lung; Mannans; Microbial Sensitivity Tests; Neutropenia; Rabbits; Survival Analysis; Tetrazolium Salts; Thiazoles; Tomography, X-Ray Computed; Triazoles | 2004 |
Retroviral delivery of TIMP-2 inhibits H-ras-induced migration and invasion in MCF10A human breast epithelial cells.
Topics: Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cells, Cultured; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Transfer Techniques; Genetic Therapy; Humans; Immunoblotting; Models, Genetic; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Phenotype; ras Proteins; Retroviridae; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Inhibitor of Metalloproteinase-2; Wound Healing | 2004 |
Cytotoxicity of fungal metabolites to lepidopteran (Spodoptera frugiperda) cell line (SF-9).
Topics: Animals; Biological Assay; Cell Line; Coloring Agents; Female; Insect Control; Mycotoxins; Ovary; Peptides; Pest Control, Biological; Spodoptera; Tetrazolium Salts; Thiazoles; Trichothecenes; Trypan Blue | 2004 |
Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin.
Topics: Animals; Antioxidants; Apigenin; Apoptosis; Calcium; Cytoprotection; DNA, Neoplasm; Dose-Response Relationship, Drug; Flavonoids; Glucuronates; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lipid Peroxidation; Membrane Potentials; Mitochondria; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Vitamin E | 2004 |
Structure and fungicidal activity of a synthetic antimicrobial peptide, P18, and its truncated peptides.
Topics: Animals; Antifungal Agents; Antimicrobial Cationic Peptides; Aspergillus; Candida albicans; Circular Dichroism; Fusarium; Gene Deletion; Leucine; Magainins; Peptides; Proline; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Trichosporon; Xenopus; Xenopus Proteins | 2004 |
Cytotoxicity and sealing properties of four classes of endodontic sealers evaluated by succinic dehydrogenase activity and confocal laser scanning microscopy.
Topics: Analysis of Variance; Animals; BALB 3T3 Cells; Carbamates; Coloring Agents; Composite Resins; Dental Bonding; Dental Cements; Dental Leakage; Epoxy Resins; Fluorescent Dyes; Humans; Lipopolysaccharides; Materials Testing; Mice; Microscopy, Confocal; Polyesters; Rhodamines; Root Canal Filling Materials; Root Canal Obturation; Succinate Dehydrogenase; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Cell death induced by vaccine adjuvants containing surfactants.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Caspase Inhibitors; Cell Cycle; Cell Death; Cell Line; Coloring Agents; Diploidy; Flow Cytometry; Fluorescent Dyes; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Necrosis; Propidium; Surface-Active Agents; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Thiazoles | 2004 |
In vitro effects of recombinant human growth hormone on growth of human gastric cancer cell line BGC823 cells.
Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Coloring Agents; DNA; G1 Phase; Growth Hormone; Human Growth Hormone; Humans; In Vitro Techniques; Organoplatinum Compounds; Oxaliplatin; Resting Phase, Cell Cycle; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2004 |
Treatment of HER-2/neu overexpressing breast cancer xenograft models with trastuzumab (Herceptin) and gefitinib (ZD1839): drug combination effects on tumor growth, HER-2/neu and epidermal growth factor receptor expression, and viable hypoxic cell fraction
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Female; Flow Cytometry; Gefitinib; Humans; Hypoxia; Mammary Neoplasms, Animal; Mice; Mice, SCID; Neoplasm Transplantation; Phosphorylation; Quinazolines; Receptor, ErbB-2; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab | 2004 |
Zeaxanthin in combination with ascorbic acid or alpha-tocopherol protects ARPE-19 cells against photosensitized peroxidation of lipids.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Carotene; Biological Assay; Cell Line; Cell Survival; Humans; Iron; Lipid Peroxidation; Oxidative Stress; Photochemistry; Photosensitizing Agents; Pigment Epithelium of Eye; Pyrimidinones; Singlet Oxygen; Tetrazolium Salts; Thiazoles; Xanthophylls; Zeaxanthins | 2004 |
Reactive oxygen species induce different cell death mechanisms in cultured neurons.
Topics: Animals; Biological Assay; Calcium; Caspases; Catalase; Cell Culture Techniques; Cell Death; Cell Survival; Cerebellum; Ionomycin; Neurons; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Xanthine; Xanthine Oxidase | 2004 |
Sertoli cell junctional proteins as early targets for different classes of reproductive toxicants.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cadherins; Cell Line; Connexin 43; Connexins; Electrophoresis, Polyacrylamide Gel; Environmental Pollutants; Estradiol Congeners; Fluorescent Antibody Technique; Immunohistochemistry; Intercellular Junctions; Male; Membrane Proteins; Metals; Occludin; Phosphodiesterase Inhibitors; Rats; Sertoli Cells; Teratogens; Tetrazolium Salts; Thiazoles | 2004 |
Interference by anti-cancer chemotherapeutic agents in the MTT-tumor chemosensitivity assay.
Topics: Antineoplastic Agents; Cisplatin; Colorimetry; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Tetrazolium Salts; Thiazoles | 2004 |
A simple quantitative method for evaluation of angiogenesis activity.
Topics: Algorithms; Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Colorimetry; Drug Evaluation, Preclinical; Endothelium, Vascular; Image Processing, Computer-Assisted; Immunohistochemistry; Organ Culture Techniques; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Tetrazolium Salts; Thiazoles | 2004 |
Soluble oligomeric Abeta disrupts the protein kinase C signaling pathway.
Topics: Amyloid beta-Peptides; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cytosol; Mice; Neuroblastoma; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles | 2004 |
Potential efficacy of p16 gene therapy for EBV-positive nasopharyngeal carcinoma.
Topics: Adenoviridae; Animals; Apoptosis; beta-Galactosidase; Blotting, Western; Carcinoma; Cell Cycle; Cell Survival; Cellular Senescence; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p16; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Gene Silencing; Genetic Therapy; Genetic Vectors; HeLa Cells; Herpesvirus 4, Human; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mice, SCID; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Oligo-3-hydroxybutyrates as potential carriers for drug delivery.
Topics: 3-Hydroxybutyric Acid; Animals; Biocompatible Materials; Blotting, Western; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cell Survival; Chloramphenicol O-Acetyltransferase; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Delivery Systems; Fibroblasts; HSP70 Heat-Shock Proteins; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Models, Chemical; Molecular Weight; Polymers; Promoter Regions, Genetic; Rats; Spectrometry, Mass, Electrospray Ionization; Temperature; Tetrazolium Salts; Thiazoles | 2004 |
Antibacterial activity of ethanolic and aqueous extracts of Acacia aroma Gill. ex Hook et Arn.
Topics: Acacia; Anti-Bacterial Agents; Bacteria; Biological Assay; Chromatography, Thin Layer; Drug Resistance, Bacterial; Ethanol; Microbial Sensitivity Tests; Plant Extracts; Plant Structures; Tetrazolium Salts; Thiazoles; Water | 2004 |
Dual role of polymorphonuclear neutrophils on the growth of Ehrlich ascites tumor (EAT) in mice.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Body Weight; Carcinoma, Ehrlich Tumor; Cytotoxicity, Immunologic; Glycogen; Hydrogen Peroxide; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neutrophils; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
FK506 abrogates delayed neuronal death via suppression of nitric oxide production in rats.
Topics: Analysis of Variance; Animals; Brain Ischemia; Cell Count; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Hippocampus; Humans; L-Lactate Dehydrogenase; Male; Microdialysis; Neuroblastoma; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Sprague-Dawley; Reperfusion; Staining and Labeling; Tacrolimus; Tetrazolium Salts; Thiazoles | 2004 |
Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption.
Topics: Adsorption; Animals; Blood Proteins; Cell Survival; Diminazene; Electrophoresis, Gel, Two-Dimensional; Excipients; Granulocytes; Humans; In Vitro Techniques; Isoelectric Focusing; Lipids; Mice; Microspheres; Particle Size; Stearic Acids; Surface Properties; Tetrazolium Salts; Thiazoles | 2004 |
Alteration of cellular phenotype and responses to oxidative stress by manganese superoxide dismutase and a superoxide dismutase mimic in RWPE-2 human prostate adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Complementary; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Humans; Male; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenotype; Plasmids; Prostatic Neoplasms; Rats; Sodium Selenite; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
In vitro assessment of copper-induced toxicity in the human hepatoma line, Hep G2.
Topics: Carcinoma, Hepatocellular; Coloring Agents; Copper; Hepatolenticular Degeneration; Humans; Liver Neoplasms; Lysosomes; Mitochondria; Neutral Red; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Trypan Blue; Tumor Cells, Cultured | 2004 |
Neuronal traits are required for glucose-induced insulin secretion.
Topics: Animals; Blotting, Northern; Cell Line; Co-Repressor Proteins; Coloring Agents; DNA-Binding Proteins; DNA, Complementary; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Nerve Tissue Proteins; Neurons; Potassium Chloride; Promoter Regions, Genetic; Repressor Proteins; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection | 2004 |
Differential regulation of resveratrol on lipopolysacchride-stimulated human macrophages with or without IFN-gamma pre-priming.
Topics: Antigen-Presenting Cells; Antigens, CD; B7-2 Antigen; Cell Death; Cell Differentiation; Cell Survival; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-12; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Phenotype; Recombinant Proteins; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Necrosis Factor-alpha | 2004 |
Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Catalase; Cell Nucleus; Comet Assay; Cytarabine; DNA Fragmentation; Flavanones; Glutathione Peroxidase; Leukemia P388; Mice; Microscopy, Fluorescence; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
A microplate indicator-based method for determining the susceptibility of multidrug-resistant Mycobacterium tuberculosis to antimicrobial agents.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Dye Dilution Technique; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tetrazolium Salts; Thiazoles; Titrimetry; Tuberculosis, Pulmonary | 2004 |
Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Histones; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Male; Mitosis; Models, Chemical; Plant Extracts; Ploidies; Prostatic Neoplasms; Quinazolines; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.
Topics: Adult; Aged; Blotting, Western; Cell Line, Tumor; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Immunohistochemistry; Lasers; Middle Aged; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Resting Phase, Cell Cycle; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Ribavirin, but not interferon alpha-2b, is associated with impaired osteoblast proliferation and differentiation in vitro.
Topics: Alkaline Phosphatase; Bone Development; Cell Death; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Interferon alpha-2; Interferon-alpha; Osteoblasts; Osteoporosis; Recombinant Proteins; Ribavirin; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Paraquat-induced apoptotic cell death in cerebellar granule cells.
Topics: Allopurinol; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Herbicides; In Situ Nick-End Labeling; Male; Mitochondria; Models, Biological; Neurons; Paraquat; Piperazines; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Vitamin E | 2004 |
Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat.
Topics: Analysis of Variance; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Glial Fibrillary Acidic Protein; Immunohistochemistry; L-Lactate Dehydrogenase; Microtubule-Associated Proteins; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; S-Nitrosoglutathione; Tetrazolium Salts; Thiazoles | 2004 |
In vitro biocompatibility assessment of poly(epsilon-caprolactone) films using L929 mouse fibroblasts.
Topics: Animals; Cell Adhesion; Cell Count; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex II; Fibroblasts; Glass; L-Lactate Dehydrogenase; Materials Testing; Membranes, Artificial; Mice; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Polyesters; Polystyrenes; Surface Properties; Tetrazolium Salts; Thiazoles | 2004 |
Biocompatibility of NGF-grafted GTG membranes for peripheral nerve repair using cultured Schwann cells.
Topics: Animals; Animals, Newborn; Calcium Phosphates; Cells, Cultured; Gelatin; Glutaral; L-Lactate Dehydrogenase; Materials Testing; Membranes, Artificial; Microscopy, Electron, Scanning; Nerve Growth Factor; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; Proteins; Rats; Rats, Inbred Lew; Schwann Cells; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2004 |
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase.
Topics: Animals; Brain Ischemia; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Enzyme Activation; Glucose; Hypoxia; L-Lactate Dehydrogenase; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Oxygen; Rats; Reperfusion Injury; Sodium; Tetrazolium Salts; Thiazoles | 2004 |
Method for determining oxygen consumption rates of static cultures from microplate measurements of pericellular dissolved oxygen concentration.
Topics: Animals; Biological Assay; Biosensing Techniques; Cell Count; Cell Culture Techniques; Cell Line; Cell Survival; Humans; Microchemistry; Oxygen; Oxygen Consumption; Tetrazolium Salts; Thiazoles | 2004 |
Effect of chlorophyllin on normothermic storage of human periodontal ligament cells.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Chlorophyllides; Coloring Agents; Culture Media; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Humans; Isotonic Solutions; Periodontal Ligament; Resting Phase, Cell Cycle; Temperature; Tetrazolium Salts; Thiazoles; Tissue Preservation | 2004 |
Low toxicity of cationic lipid-based emulsion for gene transfer.
Topics: Animals; Biocompatible Materials; Cations; Cell Line; Cell Survival; CHO Cells; Cholesterol; Cricetinae; DNA; Dose-Response Relationship, Drug; Emulsions; Flow Cytometry; Gene Transfer Techniques; Green Fluorescent Proteins; HeLa Cells; Humans; Lipids; Mice; Microscopy, Confocal; Phosphatidylethanolamines; Plasmids; Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2004 |
Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 2; Caspase 3; Caspase 7; Caspase 8; Caspases; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Etoposide; Gene Silencing; Humans; Membrane Glycoproteins; Mitochondria; Models, Biological; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Necrosis Factor-alpha | 2004 |
A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.
Topics: Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-X Protein; Benzamides; Blotting, Western; Cell Line; Cell Line, Tumor; Coloring Agents; Cytochromes c; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flavoproteins; Flow Cytometry; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Membrane Potentials; Membrane Proteins; Milk Proteins; Mitochondria; Mutation; Piperazines; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; src-Family Kinases; STAT5 Transcription Factor; Tetrazolium Salts; Thiazoles; Trans-Activators; Transfection; Up-Regulation | 2004 |
Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells.
Topics: Animals; Catalysis; Cell Division; Cell Line, Tumor; COS Cells; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Ligands; Male; Phosphorylation; Plasmids; Prostatic Neoplasms; Protein Structure, Tertiary; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcriptional Activation; Transfection | 2004 |
Mechanism of cell death induced by an antioxidant extract of Cratoxylum cochinchinense (YCT) in Jurkat T cells: the role of reactive oxygen species and calcium.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Blotting, Western; Calcium; Caspase 3; Caspase 9; Caspases; Cell Adhesion; Cell Line; Cell Membrane; Cell Survival; Clusiaceae; Coloring Agents; Cytochromes c; DNA Fragmentation; Dogs; Ferricyanides; Flow Cytometry; Glutathione; HL-60 Cells; Humans; Jurkat Cells; Lymphocytes; Membrane Potentials; Mitochondria; Models, Biological; Nucleosomes; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phosphatidylserines; Plant Extracts; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2004 |
NaoXinQing, an anti-stroke herbal medicine, reduces hydrogen peroxide-induced injury in NG108-15 cells.
Topics: Animals; Apoptosis; Catalase; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Flow Cytometry; Glutathione; Glutathione Peroxidase; Hydro-Lyases; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Medicine, Chinese Traditional; Mice; Neuroblastoma; Oxidative Stress; Stroke; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Role of apolipoprotein A-I in protecting against endotoxin toxicity.
Topics: Animals; Apolipoprotein A-I; Cell Line; Chromatography; Electrophoresis, Polyacrylamide Gel; Endotoxins; Escherichia coli; Humans; Lipopolysaccharides; Lipoproteins, HDL; Macrophages; Mice; Microscopy, Fluorescence; Protein Binding; Tetrazolium Salts; Thiazoles; Time Factors; Ultracentrifugation | 2004 |
Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro.
Topics: Antibodies, Monoclonal; Antigens, CD; B7 Antigens; B7-1 Antigen; Blotting, Western; Cell Line; Cell Proliferation; Cloning, Molecular; Coloring Agents; Cytokines; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Genetic Vectors; Glutathione Transferase; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-10; Isopropyl Thiogalactoside; Protein Structure, Tertiary; Receptors, Immunologic; Recombinant Fusion Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2004 |
Apoptosis of human primary gastric carcinoma cells induced by genistein.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Gene Expression Regulation, Neoplastic; Genistein; Humans; In Situ Nick-End Labeling; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Rapid alternative methods for detection of rifampicin resistance in Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Colorimetry; Culture Media; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitrate Reductase; Nitrate Reductases; Oxazines; Oxidation-Reduction; Peru; Reagent Kits, Diagnostic; Rifampin; Tetrazolium Salts; Thiazoles; Tuberculosis; Xanthenes | 2004 |
[In vitro cytotoxicity evaluation of comfort denture adhesive].
Topics: Adhesives; Adolescent; Biocompatible Materials; Cell Division; Cell Survival; Cells, Cultured; Denture Retention; Fibroblasts; Humans; Male; Periodontium; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2004 |
Differential activation of Smads in HeLa and SiHa cells that differ in their response to transforming growth factor-beta.
Topics: Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; DNA; Enzyme Inhibitors; G1 Phase; Genes, Reporter; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Protein Binding; Pyridines; Resting Phase, Cell Cycle; S Phase; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1; Transforming Growth Factor beta | 2004 |
Nitric oxide donating nonsteroidal anti-inflammatory drugs induce apoptosis in human prostate cancer cell systems and human prostatic stroma via caspase-3.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 3; Caspases; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Flavanones; Flow Cytometry; Humans; Ibuprofen; In Situ Nick-End Labeling; Male; Nitrates; Nitric Oxide Donors; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity.
Topics: Antineoplastic Agents; Bleomycin; Cell Death; Cell Line, Tumor; Cell Nucleus; Cell Shape; Formazans; Humans; Mitochondria; Paclitaxel; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2004 |
Effect of heat treatment on bioactivities of enamel matrix derivatives in human periodontal ligament (HPDL) cells.
Topics: Alginates; Alkaline Phosphatase; Calcification, Physiologic; Cell Differentiation; Cell Division; Cells, Cultured; Coloring Agents; Dental Enamel Proteins; Electrophoresis, Polyacrylamide Gel; Gels; Gene Expression Regulation; Hot Temperature; Humans; Mitogens; Osteoblasts; Periodontal Ligament; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2004 |
Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells.
Topics: Anthraquinones; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Survival; Coloring Agents; Cyclin-Dependent Kinases; Cyclins; DNA; DNA Fragmentation; Emodin; Flow Cytometry; G2 Phase; HL-60 Cells; Humans; Indicators and Reagents; Mitosis; Tetrazolium Salts; Thiazoles | 2004 |
Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue.
Topics: Acrolein; Animals; Antioxidants; Axons; Cell Membrane; Ethidium; Female; Fluorescent Dyes; Guinea Pigs; Horseradish Peroxidase; L-Lactate Dehydrogenase; Lipid Peroxidation; Mitochondria; Oxidative Stress; Spinal Cord; Spinal Cord Injuries; Synaptosomes; Tetrazolium Salts; Thiazoles | 2004 |
Decreased nicotinic receptors in PC12 cells and rat brains influenced by fluoride toxicity--a mechanism relating to a damage at the level in post-transcription of the receptor genes.
Topics: Animals; Antioxidants; Blotting, Western; Brain Chemistry; Cell Survival; Female; Fluorides; Lipid Peroxidation; Male; Nuclease Protection Assays; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Protein Processing, Post-Translational; Proteins; Rats; Rats, Wistar; Receptors, Nicotinic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Vitamin E | 2004 |
Erk1/2 and Akt kinases are involved in the protective effect of aniracetam in astrocytes subjected to simulated ischemia in vitro.
Topics: Animals; Apoptosis; Astrocytes; Benzimidazoles; Blotting, Western; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Fluorescent Dyes; L-Lactate Dehydrogenase; Male; Mitogen-Activated Protein Kinases; Neuroglia; Neuroprotective Agents; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidinones; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2004 |
Acidic oligosaccharide sugar chain, a marine-derived acidic oligosaccharide, inhibits the cytotoxicity and aggregation of amyloid beta protein.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cerebral Cortex; Humans; Lipid Peroxidation; Membrane Potentials; Mitochondria; Peptide Fragments; Phaeophyceae; Rats; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 2004 |
Polysaccharide extract isolated from ganoderma lucidum protects rat cerebral cortical neurons from hypoxia/reoxygenation injury.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Fluorescent Antibody Technique; Hypoxia, Brain; Malondialdehyde; Microscopy, Confocal; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Oxygen; Polysaccharides; Rats; Rats, Sprague-Dawley; Reishi; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
CpG immunostimulatory oligodeoxynucleotide 1826 enhances antitumor effect of interleukin 12 gene-modified tumor vaccine in a melanoma model in mice.
Topics: Animals; Antineoplastic Agents; Cancer Vaccines; Cell Line, Tumor; CpG Islands; Cytokines; Disease Progression; DNA; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Dyes; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Interleukin-12; Lymphatic Metastasis; Macrophages; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Oligonucleotides; Spleen; Tetrazolium Salts; Th1 Cells; Thiazoles; Time Factors | 2004 |
Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line.
Topics: Amino Acids; Aminobutyrates; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Agonists; Fluorouracil; Humans; Ligands; Organophosphonates; Receptors, Metabotropic Glutamate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Impaired IgG production in mice deficient for heat shock transcription factor 1.
Topics: Animals; Blotting, Northern; Blotting, Western; Bromodeoxyuridine; Cell Division; Chemokine CCL5; Chemokines; Chemokines, CC; Chromatin; Coloring Agents; Cytokines; Databases as Topic; DNA-Binding Proteins; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Heat Shock Transcription Factors; Homozygote; HSP70 Heat-Shock Proteins; Immunoglobulin G; Inflammation; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Nitric Oxide; Precipitin Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep; Spleen; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2004 |
Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine.
Topics: Acetylcysteine; Animals; Apoptosis; Azathioprine; Caspase 3; Caspases; Cell Survival; Cytochromes c; DNA; DNA Fragmentation; Glutathione; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Male; Mitochondria, Liver; Mitogen-Activated Protein Kinase 3; Necrosis; Oxygen Consumption; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Stress, Physiological; Superoxides; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 2004 |
Heparin regulates survival and differentiation of mesencephalic progenitors mediated via FGF2 in vitro.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Count; Cell Differentiation; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Fibroblast Growth Factor 2; Gene Expression Regulation; Heparin; Immunohistochemistry; Mesencephalon; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Tetrazolium Salts; Thiazoles; Tubulin; Tyrosine 3-Monooxygenase | 2004 |
Comparative immunogenecity of foot and mouth disease virus antigens in FMD-haemorrhagic septicaemia combined vaccine and FMD vaccine alone in buffalo calves.
Topics: Animals; Antibody Formation; Antigens, Viral; Buffaloes; Cell Division; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Hemorrhagic Septicemia; Immunity, Cellular; Immunoglobulin M; Leukocytes, Mononuclear; Tetrazolium Salts; Thiazoles; Time Factors; Vaccines | 2004 |
Localization and function of the brain excitatory amino acid transporter type 1 in cardiac mitochondria.
Topics: Adenoviridae; Animals; Aspartic Acid; Blotting, Northern; Brain; Cells, Cultured; Coloring Agents; Cytochromes c; Digitonin; DNA, Complementary; Excitatory Amino Acid Transporter 1; Genetic Vectors; Glutamic Acid; Hypoxia; Immunoblotting; Immunohistochemistry; Malates; Microscopy, Fluorescence; Mitochondria; Mitochondria, Heart; Myocardium; Open Reading Frames; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
Cytotoxic effects of environmentally relevant chlorophenols on L929 cells and their mechanisms.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Chlorophenols; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Mice; Microscopy, Fluorescence; Necrosis; Quantitative Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells.
Topics: Antifungal Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cerulenin; Coloring Agents; DNA; Dose-Response Relationship, Drug; Drug Synergism; Fatty Acid Synthases; Humans; Inhibitory Concentration 50; Tetrazolium Salts; Thiazoles; Time Factors; Vinblastine; Vinorelbine | 2004 |
The relationship of the human glutathione S-transferase P1 polymorphism and chemotherapeutic sensitivity in head and neck squamous carcinoma.
Topics: Alleles; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Multiple; Exons; Genotype; Glutathione Transferase; Head and Neck Neoplasms; Heterozygote; Humans; Inhibitory Concentration 50; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Tetrazolium Salts; Thiazoles; Valine | 2004 |
Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells.
Topics: Agaricales; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chromatin; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; G1 Phase; Humans; Immunoblotting; Mycelium; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Induction of apoptosis by ar-turmerone on various cell lines.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; K562 Cells; Ketones; Models, Chemical; Plant Extracts; Rats; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Time Factors; Toluene; U937 Cells | 2004 |
Adenoviral-mediated transfer of p53 gene enhances TRAIL-induced apoptosis in human hepatocellular carcinoma cells.
Topics: Adenoviridae; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Death; Cell Line, Transformed; Cell Line, Tumor; Coloring Agents; Down-Regulation; Genes, p53; Genetic Therapy; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Glycoproteins; Proteins; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2004 |
Differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid is enhanced in combination with caffeic acid.
Topics: Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Caffeic Acids; Cell Adhesion Molecules; Cell Differentiation; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; GPI-Linked Proteins; HL-60 Cells; Humans; Immunophenotyping; Leukemia, Promyelocytic, Acute; Models, Chemical; Tetrazolium Salts; Thiazoles; Time Factors; Tretinoin | 2004 |
Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kappaB activation.
Topics: Acetylcysteine; Aging; Aldehydes; Animals; Apoptosis; Blotting, Western; Cell Nucleus; Cell Survival; Coloring Agents; Culture Media, Serum-Free; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Free Radicals; Gene Expression Regulation; Lipid Peroxidation; Luciferases; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Oxidation-Reduction; Oxidative Stress; Prostate; Rats; Sulfones; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2004 |
Novel cytotoxic bufadienolides derived from bufalin by microbial hydroxylation and their structure-activity relationships.
Topics: Bacteria; Biological Assay; Bufanolides; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; Enzyme Inhibitors; Fungi; HeLa Cells; HL-60 Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Oxygen; Spectrophotometry; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2004 |
Gastrodia elata prevents rat pheochromocytoma cells from serum-deprived apoptosis: the role of the MAPK family.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Dicumarol; Drugs, Chinese Herbal; Flavonoids; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Neuroprotective Agents; PC12 Cells; Phosphorylation; Pyridines; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2004 |
Possible mechanism of miltefosine-mediated death of Leishmania donovani.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Cell Division; Coloring Agents; Cricetinae; Cricetulus; DNA Fragmentation; DNA, Protozoan; In Situ Nick-End Labeling; Indicators and Reagents; Leishmania donovani; Leishmaniasis, Visceral; Macrophages; Nucleosomes; Phosphorylcholine; Poly(ADP-ribose) Polymerases; Propidium; Tetrazolium Salts; Thiazoles | 2004 |
Cytotoxicity of oxidized low-density lipoprotein in cultured RPE cells is dependent on the formation of 7-ketocholesterol.
Topics: Adenosine Triphosphate; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Drug Synergism; Humans; Hydroxycholesterols; Ketocholesterols; Lipoproteins, LDL; Oxidation-Reduction; Pigment Epithelium of Eye; Tetrazolium Salts; Thiazoles; Time Factors; Transition Elements | 2004 |
Complexes of ruthenium(III) with some 2-aminothiazole derivatives/synthesis, properties and pharmacological studies.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Electron Spin Resonance Spectroscopy; Humans; Indicators and Reagents; Lethal Dose 50; Ligands; Magnetic Resonance Spectroscopy; Ruthenium; Spectrophotometry, Infrared; Temperature; Tetrazolium Salts; Thiazoles | 2004 |
Cell growth after withdrawal of gefitinib ("Iressa", ZD1839) in human lung cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Quinazolines; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Mifepristone induces growth arrest, caspase activation, and apoptosis of estrogen receptor-expressing, antiestrogen-resistant breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Fragmentation; Drug Resistance, Neoplasm; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; G1 Phase; Hormone Antagonists; Humans; Immunoblotting; Mifepristone; Phosphorylation; Receptors, Estrogen; Receptors, Progesterone; Resting Phase, Cell Cycle; Tamoxifen; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; DNA; DNA Damage; DNA Repair; Down-Regulation; Drug Evaluation, Preclinical; Endonucleases; Etoposide; Exonucleases; Fluorouracil; HeLa Cells; Humans; Kinetics; Mice; Mitomycin; Neoplasms; Pentamidine; Plasmids; Recombination, Genetic; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery.
Topics: Alkaloids; Antioxidants; Apoptosis; Benzophenanthridines; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin-Dependent Kinases; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Isoquinolines; Keratinocytes; Male; Models, Biological; Models, Chemical; Plant Extracts; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles | 2004 |
Neuroprotective effects of Ptychopetalum olacoides Bentham (Olacaceae) on oxygen and glucose deprivation induced damage in rat hippocampal slices.
Topics: Animals; Antioxidants; Cell Survival; Dimethyl Sulfoxide; Ethanol; Free Radicals; Glucose; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Neuroprotective Agents; Olacaceae; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Solvents; Tetrazolium Salts; Thiazoles | 2004 |
Effect of ammonium chloride on the growth and metabolism of bovine ovarian granulosa cells and the development of ovine oocytes matured in the presence of bovine granulosa cells previously exposed to ammonium chloride.
Topics: Ammonium Chloride; Animals; Cattle; Cell Division; Coculture Techniques; Culture Media, Conditioned; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Mammalian; Estradiol; Female; Fertilization in Vitro; Granulosa Cells; Oocytes; Oxidation-Reduction; Progesterone; Proteins; Pyruvic Acid; Tetrazolium Salts; Thiazoles | 2004 |
TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
Topics: Adenosine Diphosphate Ribose; Animals; Blotting, Western; Calcium; Cell Death; Cell Line; Cell Line, Tumor; Cell Membrane; Electrophysiology; Enzyme Activation; Fluorescent Dyes; Fluorometry; Humans; Hydrogen Peroxide; Insulinoma; Ion Channel Gating; Ion Channels; Membrane Proteins; Organic Chemicals; Oxidative Stress; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Rats; Tetrazolium Salts; Thiazoles; TRPM Cation Channels | 2004 |
Oxidative stress impairs glutamate uptake in fibroblasts from patients with Alzheimer's disease.
Topics: Acetylcysteine; Adenosine Triphosphate; Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Animals; Antioxidants; Case-Control Studies; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fibroblasts; Free Radicals; Glutamic Acid; Glutathione; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Biphasic effect of daidzein on cell growth of human colon cancer cells.
Topics: Alkaline Phosphatase; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Estrogens, Non-Steroidal; Flow Cytometry; G1 Phase; Humans; Isoflavones; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia.
Topics: Animals; Antioxidants; Blotting, Western; Caspase 3; Caspases; Catalase; Cell Hypoxia; Cell Line; Cell Survival; Dioxoles; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Lignans; Mice; Microglia; Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Estrogen increases proteasome activity in murine microglial cells.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cell Line; Chymotrypsin; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Estradiol; Estrogens; Interferon-gamma; Leupeptins; Mice; Microglia; Protease Inhibitors; Proteasome Endopeptidase Complex; Receptors, Estradiol; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid beta-protein in cultured cells.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Aspartic Acid Endopeptidases; Blotting, Western; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endopeptidases; Gene Expression Regulation; Humans; Immunoprecipitation; L-Lactate Dehydrogenase; Neuroblastoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
Taurine chloramine and taurine bromamine induce heme oxygenase-1 in resting and LPS-stimulated J774.2 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Taurine; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition.
Topics: Animals; Antimycin A; Bongkrekic Acid; Brain; Calcimycin; Calcium; Catalase; Cell Survival; Cyclosporins; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex II; Enzyme Inhibitors; Female; In Vitro Techniques; Ionophores; Malonates; Membrane Potentials; Methylmalonic Acid; Mitochondria; NADP; Neurons; Nitro Compounds; Oxygen Consumption; PC12 Cells; Permeability; Propionates; Rats; Rotenone; Tacrolimus; Tetrazolium Salts; Thiazoles; Uncoupling Agents | 2004 |
The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurones from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.
Topics: Androstadienes; Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavonoids; Indoles; Mitogen-Activated Protein Kinases; Neurons; Peptide Fragments; Phosphatidylinositol 3-Kinases; Potassium; Precipitin Tests; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetanus Toxin; Tetrazolium Salts; Thiazoles; Time Factors; Wortmannin | 2004 |
Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma.
Topics: Adenoviridae; Animals; Bromodeoxyuridine; Carcinoma, Medullary; Cell Division; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Multiple Endocrine Neoplasia Type 2a; Oncogene Proteins; Oncogene Proteins, Fusion; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms | 2004 |
Effects of enamel matrix derivative on proliferation and differentiation of primary osteoblasts.
Topics: Alkaline Phosphatase; Animals; Antimetabolites; Bromodeoxyuridine; Calcium; Cell Culture Techniques; Cell Differentiation; Cell Division; Collagen; Coloring Agents; Dental Enamel Proteins; Mice; Microscopy, Electron; Osteoblasts; Tetrazolium Salts; Thiazoles | 2004 |
A new anthraquinone and cytotoxic curvularins of a Penicillium sp. from the rhizosphere of Fallugia paradoxa of the Sonoran desert.
Topics: Anthraquinones; Antibiotics, Antineoplastic; Cell Line, Tumor; Desert Climate; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Penicillium; Plant Roots; Rosaceae; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Zearalenone | 2004 |
Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas.
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Ceramides; Chromatography, Liquid; Coloring Agents; DNA, Complementary; Head and Neck Neoplasms; Humans; Mass Spectrometry; Membrane Potentials; Membrane Proteins; Mice; Mitochondria; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saccharomyces cerevisiae Proteins; Sphingosine N-Acyltransferase; Telomerase; Tetrazolium Salts; Thiazoles; Trypan Blue | 2004 |
Polyplexes and lipoplexes for mammalian gene delivery: from traditional to microarray screening.
Topics: Cell Line; DNA; Drug Delivery Systems; Drug Evaluation, Preclinical; Electrophoresis, Agar Gel; Gene Transfer Techniques; Humans; Lipids; Oligonucleotide Array Sequence Analysis; Pharmaceutical Vehicles; Polymers; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
Induction of apoptosis and necrosis in A549 cells by the cis-Pt(II) complex of 3-aminoflavone in comparison with cis-DDP.
Topics: Acridine Orange; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cell Survival; Cisplatin; Ethidium; Flavonoids; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Molecular Structure; Necrosis; Tetrazolium Salts; Thiazoles | 2004 |
Manipulation of PrPres production in scrapie-infected neuroblastoma cells.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Blotting, Western; Brain; Carcinogens; Cell Count; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidase K; Enzyme-Linked Immunosorbent Assay; Glycosylation; Humans; Interleukin-6; Mice; Microglia; Neuroblastoma; Prions; PrPSc Proteins; Scrapie; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tretinoin | 2004 |
Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549.
Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase 7; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA, Complementary; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Plant Extracts; Scutellaria; Tetrazolium Salts; Thiazoles | 2004 |
Differential expression profiles of PLC-beta1 and -delta1 in primary cultured rat cortical neurons treated with N-methyl-D-aspartate and peroxynitrite.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoenzymes; N-Methylaspartate; Neurons; Penicillamine; Peroxynitrous Acid; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Type C Phospholipases | 2004 |
Co-treatment with ethanol enhances the toxicity of 6-hydroxydopamine.
Topics: Adrenergic Agents; Animals; Apoptosis; Cell Line; Cell Survival; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Flow Cytometry; Humans; Neuroblastoma; Oxidopamine; Rats; Tetrazolium Salts; Thiazoles | 2004 |
Myosin Va is proteolysed in rat cerebellar granule neurons after excitotoxic injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Cerebellum; Cysteine Proteinase Inhibitors; Drug Interactions; Excitatory Amino Acids; Glycoproteins; Leupeptins; Myosin Heavy Chains; Myosin Type V; Neurons; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytosol; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Dominant; Humans; In Situ Nick-End Labeling; MAP Kinase Kinase 1; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinase 3; Models, Biological; Phosphatidylinositol 3-Kinases; Plasmids; Protein Denaturation; Protein Folding; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Subcellular Fractions; Tetrazolium Salts; Thapsigargin; Thiazoles; Time Factors; TOR Serine-Threonine Kinases; Transcription, Genetic; Tunicamycin; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2004 |
The alpha7 nicotinic acetylcholine receptor-selective antagonist, methyllycaconitine, partially protects against beta-amyloid1-42 toxicity in primary neuron-enriched cultures.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Animals, Newborn; Brain; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Mice; Neurons; Nicotinic Antagonists; Peptide Fragments; Receptors, Nicotinic; Tetrazolium Salts; Thiazoles | 2004 |
The involvement of oxidative stress in bovine herpesvirus type 4-mediated apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Azoles; Butylated Hydroxyanisole; Cattle; Cell Line; Cell Proliferation; Coloring Agents; DNA Fragmentation; Herpesvirus 4, Bovine; Isoindoles; Kidney; Models, Statistical; Organoselenium Compounds; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Transglutaminase contributes to CPPD crystal formation in osteoarthritis.
Topics: Animals; Calcium Pyrophosphate; Cartilage; Cell Survival; Cells, Cultured; Chondrocytes; Chromatography, High Pressure Liquid; Humans; Immunohistochemistry; Osteoarthritis; Swine; Tetrazolium Salts; Thiazoles; Transglutaminases | 2004 |
Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells.
Topics: Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indicators and Reagents; Microsomes; Neoplasms; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Rhodamines; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2004 |
Glutamate mediates cell death and increases the Bax to Bcl-2 ratio in a differentiated neuronal cell line.
Topics: Animals; Annexin A5; bcl-2-Associated X Protein; Blotting, Western; Cell Count; Cell Death; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamic Acid; Neuroblastoma; Neurons; Proto-Oncogene Proteins c-bcl-2; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl-4-quinolones.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; G2 Phase; Humans; K562 Cells; Mitosis; Quinolones; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2004 |
Mutant nicastrin protein can induce the cytochrome c release and the Bax expression.
Topics: Amyloid Precursor Protein Secretases; bcl-2-Associated X Protein; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Mutational Analysis; Gene Expression Regulation; Humans; Membrane Glycoproteins; Mitochondria; Mutagenesis, Site-Directed; Mutation; Neuroblastoma; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
The role of hypoxia inducible factor 1alpha in cobalt chloride induced cell death in mouse embryonic fibroblasts.
Topics: Animals; Blotting, Western; Caspases; Cell Death; Cell Line; Cell Shape; Cobalt; DNA-Binding Proteins; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Genes, bcl-2; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transcription Factors | 2004 |
c-fos mRNA expression in rat cortical neurons during glutamate-mediated excitotoxicity.
Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acids; Gene Expression; Genes, fos; Glutamates; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2004 |
Optimizing electroporation conditions for intracellular delivery of morpholino antisense oligonucleotides directed against the hepatitis C virus internal ribosome entry site.
Topics: Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Electroporation; Genetic Techniques; HeLa Cells; Hepacivirus; Humans; Luciferases; Nucleic Acid Conformation; Oligonucleotides, Antisense; Plasmids; Ribosomes; RNA, Viral; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Activation of RB/E2F signaling pathway is required for the modulation of hepatitis C virus core protein-induced cell growth in liver and non-liver cells.
Topics: 4-Butyrolactone; Blotting, Northern; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA-Binding Proteins; DNA, Complementary; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; HeLa Cells; Hepacivirus; Humans; Liver; Luciferases; Phosphorylation; Plasmids; Protein Kinase Inhibitors; Retinoblastoma Protein; RNA; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Transcription Factors; Tumor Suppressor Protein p53 | 2004 |
Toxicity of herbicides determined with a microbial test.
Topics: Biological Assay; Coloring Agents; Half-Life; Herbicides; Sinorhizobium meliloti; Soil Pollutants; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2004 |
Prolonged cytotoxic effect of colchicine released from biodegradable microspheres.
Topics: Biocompatible Materials; Biodegradation, Environmental; Cell Line; Cell Survival; Colchicine; Dosage Forms; Excipients; Gelatin; HeLa Cells; Humans; Microspheres; Particle Size; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2004 |
Effects of root-end filling materials and eugenol on mitochondrial dehydrogenase activity and cytotoxicity to human periodontal ligament fibroblasts.
Topics: Alkaline Phosphatase; Cell Survival; DNA; Eugenol; Fibroblasts; Flow Cytometry; Gingiva; Humans; Mitochondria; Oxidoreductases; Periodontal Ligament; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles | 2004 |
Potent antitumor efficacy of an E1B 55kDa-deficient adenovirus carrying murine endostatin in hepatocellular carcinoma.
Topics: Adenoviridae; Adenovirus E1B Proteins; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Endostatins; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Humans; Immunoenzyme Techniques; Liver Neoplasms; Mice; Mice, Nude; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured; Virus Replication | 2005 |
Antioxidants are required during the early critical period, but not later, for neuronal survival.
Topics: Animals; Antioxidants; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fluorescent Antibody Technique; Glutamic Acid; Hydrogen Peroxide; Neurons; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tubulin | 2004 |
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.
Topics: Agar; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; DNA; Dose-Response Relationship, Drug; Doxorubicin; Epithelial Cells; Flow Cytometry; Fluorouracil; Genes, Dominant; Humans; Immunohistochemistry; Mice; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides; Phenotype; rhoA GTP-Binding Protein; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Wound Healing | 2004 |
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cattle; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Humans; L-Lactate Dehydrogenase; Multidrug Resistance-Associated Proteins; Oxidation-Reduction; Propionates; Quinolines; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles; Verapamil | 2004 |
Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts.
Topics: Aminopeptidases; Animals; Apoptosis; Carboxypeptidases; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cell Line, Transformed; Cell Survival; Coloring Agents; Culture Media; Cysteine Endopeptidases; Cytochromes c; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Endopeptidases; Fas Ligand Protein; fas Receptor; Fibroblasts; Flow Cytometry; Golgi Apparatus; Humans; Intercellular Adhesion Molecule-1; Lymphocytes; Lysosomes; Mannosephosphates; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Mucolipidoses; Phenotype; Phosphorylation; Recombinant Proteins; Signal Transduction; Skin; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2004 |
Taxol induces caspase-10-dependent apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Caspase 10; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspases; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Survival; Coloring Agents; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Fas-Associated Death Domain Protein; Flow Cytometry; Genes, Dominant; Humans; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Models, Biological; Paclitaxel; Plasmids; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Assay; Cell Survival; Cisplatin; Docetaxel; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluoresceins; Humans; Principal Component Analysis; Taxoids; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vinblastine | 2004 |
Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatin; Coloring Agents; DNA, Complementary; DNA, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; In Situ Nick-End Labeling; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Precipitin Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Up-Regulation | 2004 |
Effects of different sterilization methods on the morphology, mechanical properties, and cytotoxicity of chitosan membranes used as wound dressings.
Topics: Animals; Bandages; Cell Survival; Chitosan; Chlorocebus aethiops; Disinfectants; Ethanol; Ethylene Oxide; Freeze Drying; Gamma Rays; Membranes, Artificial; Sterilization; Stress, Mechanical; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Vero Cells | 2004 |
Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells.
Topics: Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Environmental Pollutants; Female; Humans; L-Lactate Dehydrogenase; Luciferases; Oxazines; Polybrominated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Xanthenes | 2004 |
Alkylating benzamides with melanoma cytotoxicity.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Benzamides; Cell Line, Tumor; Cell Survival; Chlorambucil; Coloring Agents; Disease Models, Animal; Drug Delivery Systems; Drug Design; Ethylamines; HeLa Cells; Humans; Melanoma; Melanoma, Experimental; Mice; Models, Chemical; Neoplasms, Experimental; NIH 3T3 Cells; Procainamide; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2004 |
Viability assessment in sandwich-cultured rat hepatocytes after xenobiotic exposure.
Topics: Animals; Biological Assay; Cell Culture Techniques; Cell Survival; Coloring Agents; Hepatocytes; Indicators and Reagents; L-Lactate Dehydrogenase; Oxazines; Propidium; Rats; Tetrazolium Salts; Thiazoles; Xanthenes; Xenobiotics | 2004 |
Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer.
Topics: Actinin; Adenoviridae; Amino Acid Sequence; Antibodies; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Collagen; Coloring Agents; DNA, Complementary; Down-Regulation; Drug Combinations; Epidermal Growth Factor; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Laminin; Models, Genetic; Molecular Sequence Data; Phosphorylation; Plasmids; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteoglycans; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Two-Hybrid System Techniques; Up-Regulation | 2004 |
Regulated expression of VP16CREB in neuroblastoma cells: analysis of differentiation and apoptosis.
Topics: Animals; Apoptosis; Blotting, Western; Bucladesine; Cell Count; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Gene Expression Regulation; Genetic Vectors; Genomics; Green Fluorescent Proteins; Mice; Neuroblastoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
SU5416 inhibited VEGF and HIF-1alpha expression through the PI3K/AKT/p70S6K1 signaling pathway.
Topics: Binding Sites; Blotting, Northern; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Indoles; Luciferases; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Ribosomal Protein S6 Kinases, 70-kDa; RNA; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A | 2004 |
Zinc coupling potentiates anti-HIV-1 activity of baicalin.
Topics: Anti-HIV Agents; Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Humans; Models, Chemical; Recombinant Proteins; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors; Zinc | 2004 |
Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
Topics: Animals; Behavior, Animal; Blotting, Western; Butadienes; Cell Death; Cell Survival; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Lithium Chloride; Male; Mice; Mitogen-Activated Protein Kinase 1; Neurotoxicity Syndromes; Nitriles; Organ Culture Techniques; Phosphorylation; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Neuropeptide PACAP inhibits hypoxic activation of brain microglia: a protective mechanism against microglial neurotoxicity in ischemia.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain Ischemia; Cell Survival; Cells, Cultured; Coculture Techniques; Hypoxia; Microglia; Nerve Growth Factors; Neuropeptides; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Prosencephalon; Rats; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2004 |
Assemblages of prion fragments: novel model systems for understanding amyloid toxicity.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Astrocytes; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Disease Models, Animal; Lipids; Membrane Microdomains; Microscopy, Electron, Transmission; Peptide Fragments; Peptides; Prions; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrenes; Rats; Rats, Wistar; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synaptosomes; Temperature; Tetrazolium Salts; Thiazoles | 2004 |
(-)-Epigallocatechin gallate inhibits lipopolysaccharide-induced microglial activation and protects against inflammation-mediated dopaminergic neuronal injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Blotting, Western; Carbocyanines; Catechin; Cell Count; Cells, Cultured; Culture Media, Conditioned; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipopolysaccharides; Microglia; Microtubule-Associated Proteins; Neuroblastoma; Neurons; Nitric Oxide; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2004 |
Effects of ox-LDL on number and activity of circulating endothelial progenitor cells.
Topics: Adult; Blood Cell Count; Cell Adhesion; Cell Movement; Cell Proliferation; Coronary Artery Disease; Endothelial Cells; Flow Cytometry; Humans; Lipoproteins, LDL; Neovascularization, Physiologic; Stem Cells; Tetrazolium Salts; Thiazoles | 2004 |
IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cell Size; Cells, Cultured; Enzyme Activators; Enzyme Inhibitors; Glomerular Mesangium; Immunoblotting; Immunoglobulin A; Ionomycin; Ionophores; Isoenzymes; Mice; Muscle Contraction; Phenanthridines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2004 |
Analysis of the human periodontal ligament fibroblast response to the cytolethal distending toxin produced by actinobacillus actinomycetemcomitans.
Topics: Aggregatibacter actinomycetemcomitans; Animals; Bacterial Toxins; Cell Count; Cell Division; Cell Survival; CHO Cells; Coloring Agents; Cricetinae; Cricetulus; Fibroblasts; Humans; Periodontal Ligament; Protein Subunits; Tetrazolium Salts; Thiazoles; Trypan Blue; Virulence | 2001 |
NF-kappaB family proteins participate in multiple steps of hematopoiesis through elimination of reactive oxygen species.
Topics: Animals; Apoptosis; Blotting, Northern; Cell Line; Cell Separation; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Conditioned; Cytokines; Erythropoietin; Flow Cytometry; Glutathione; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; I-kappa B Proteins; Immunoblotting; Interleukin-3; Mice; Mice, Inbred BALB C; NF-kappa B; Plasmids; Reactive Oxygen Species; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tetracycline; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Induction of ovarian cancer cell apoptosis by 1,25-dihydroxyvitamin D3 through the down-regulation of telomerase.
Topics: Apoptosis; Calcitriol; Catalytic Domain; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cloning, Molecular; Coloring Agents; DNA-Binding Proteins; Down-Regulation; Female; Flow Cytometry; Humans; Ovarian Neoplasms; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Reverse Transcription; RNA, Messenger; Telomerase; Telomere; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection | 2004 |
Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Female; Humans; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tetrazolium Salts; Thiazoles; Thionucleotides; Time Factors; Up-Regulation | 2004 |
Synthesis and endosomolytic properties of poly(amidoamine) block copolymers.
Topics: Animals; Biocompatible Materials; Drug Carriers; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Models, Chemical; Plant Proteins; Polyamines; Polymers; Ribosome Inactivating Proteins, Type 1; Temperature; Tetrazolium Salts; Thiazoles | 2004 |
Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells.
Topics: Apoptosis; Blotting, Western; Caspase Inhibitors; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Diterpenes; Diterpenes, Clerodane; Enzyme Activation; Fas Ligand Protein; Genes, bcl-2; Humans; In Situ Nick-End Labeling; Male; Membrane Glycoproteins; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Rhodamines; Signal Transduction; Tetrazolium Salts; Thiazoles | 2004 |
A novel fusion suicide gene yeast CDglyTK plays a role in radio-gene therapy of nasopharyngeal carcinoma.
Topics: Analysis of Variance; Animals; Blotting, Western; Carcinoma; Combined Modality Therapy; Cytosine Deaminase; Flucytosine; Ganciclovir; Genes, Fungal; Genes, Transgenic, Suicide; Genetic Therapy; Herpesvirus 1, Human; Humans; Mice; Mice, Inbred BALB C; Nasopharyngeal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transfection; Tumor Cells, Cultured; Yeasts | 2004 |
Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells.
Topics: Apoptosis; Blast Crisis; Blotting, Western; Fusion Proteins, bcr-abl; Humans; In Situ Nick-End Labeling; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; RNA Interference; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Suppression of bcl-2 gene by RNA interference increases chemosensitivity to cisplatin in nasopharyngeal carcinoma cell line CNE1.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Blotting, Western; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cloning, Molecular; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Humans; Molecular Sequence Data; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Tetrazolium Salts; Thiazoles; Transfection | 2004 |
Preparation and characterisation in simulated body conditions of glutaraldehyde crosslinked chitosan membranes.
Topics: Acetic Acid; Animals; Biocompatible Materials; Body Temperature; Chitosan; Coloring Agents; Cross-Linking Reagents; Crustacea; Glutaral; Humans; Kinetics; Materials Testing; Membranes, Artificial; Polymers; Sodium Hydroxide; Solvents; Stress, Mechanical; Temperature; Tensile Strength; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2004 |
Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.
Topics: Animals; Antimetabolites; Antioxidants; Apoptosis; Bisbenzimidazole; Buthionine Sulfoximine; Carcinogens; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neostriatum; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Staurosporine; Tetrazolium Salts; Thiazoles; Tocotrienols; Vitamin E | 2004 |
Effects of cured dentin bonding materials on human monocyte viability.
Topics: Bisphenol A-Glycidyl Methacrylate; Cell Survival; Cells, Cultured; Coloring Agents; Composite Resins; Dentin-Bonding Agents; Humans; Materials Testing; Monocytes; Polymethacrylic Acids; Resin Cements; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Morphine aggravates the apoptosis of simian immunodeficiency virus infected CEM x174 cells in the prolonged culture in vitro.
Topics: Annexin A5; Apoptosis; Blotting, Western; Cell Cycle; Cell Line; Cell Survival; Humans; Hybrid Cells; Lymphotoxin-alpha; Morphine; Narcotics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simian Acquired Immunodeficiency Syndrome; Tetrazolium Salts; Thiazoles | 2004 |
Antiviral activity of CYC202 in HIV-1-infected cells.
Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; Apoptosis; CDC2-CDC28 Kinases; Cell Cycle; Chromatin Immunoprecipitation; Cyclin E; Cyclin-Dependent Kinase 2; DNA Fragmentation; DNA, Viral; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Flow Cytometry; Genome, Viral; HIV-1; Humans; Immunoblotting; Inhibitory Concentration 50; Leukocytes, Mononuclear; Monocytes; Mutation; Phosphorylation; Purines; RNA Interference; RNA, Small Interfering; Roscovitine; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic | 2005 |
Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
Topics: Antineoplastic Agents; Ascorbic Acid; Azoles; Catalase; Cell Line, Tumor; Chelating Agents; Coloring Agents; DNA; DNA Damage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Free Radicals; Humans; Hydrazones; Hydrogen Peroxide; Iron; Isoindoles; Ligands; Models, Chemical; Organoselenium Compounds; Oxidation-Reduction; Oxygen; Plasmids; Pyridines; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
A novel peptide isolated from a phage display peptide library with trastuzumab can mimic antigen epitope of HER-2.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens; Antineoplastic Agents; Binding, Competitive; Blotting, Western; Cell Line, Tumor; Coloring Agents; DNA; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epitopes; Escherichia coli; Genetic Vectors; Glutathione Transferase; Humans; Immunoglobulin G; Mice; Mice, Inbred BALB C; Models, Molecular; Mutation; Neoplasms; NIH 3T3 Cells; Peptide Library; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptor, ErbB-2; Recombinant Fusion Proteins; Recombinant Proteins; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Trastuzumab | 2005 |
CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Coloring Agents; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Inhibitor of Apoptosis Proteins; Male; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Mitosis; Neoplasm Metastasis; Neoplasm Proteins; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Rhodamines; Survivin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2005 |
Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor.
Topics: Antibodies, Monoclonal; Blotting, Western; CD3 Complex; Cell Line, Tumor; Cell Proliferation; Chromium Radioisotopes; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Immunoglobulin Variable Region; Immunotherapy; Leukemia Virus, Gibbon Ape; Lymphocytes; Neoplasms; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2005 |
A correlation between membrane cholesterol level, cell adhesion and tumourigenicity of polyoma virus transformed cells.
Topics: Actins; Animals; Cell Adhesion; Cell Line; Cell Line, Transformed; Cell Membrane; Cell Proliferation; Cell Transformation, Viral; CHO Cells; Cholesterol; Coloring Agents; Cricetinae; Female; Fibroblasts; Fibronectins; Integrin alpha5beta1; Integrins; Male; Mice; Mice, Nude; Neoplasms; Polyomavirus; Rats; Spectrometry, Fluorescence; Talin; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
2-(Arylpropionylamino)- and 2-(arylacryloylamino)benzophenones: farnesyltransferase inhibition and antimalarial activity.
Topics: Alkyl and Aryl Transferases; Animals; Antimalarials; Benzophenones; Drug Screening Assays, Antitumor; Escherichia coli; Farnesyltranstransferase; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plasmodium falciparum; Spectrometry, Fluorescence; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2004 |
Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate.
Topics: Animals; Antibiotics, Antineoplastic; Carrier Proteins; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Doxorubicin; Drug Stability; Excipients; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Mice; Mice, Nude; Microscopy, Confocal; Microspheres; Polyethylene Glycols; Receptors, Cell Surface; Tetrazolium Salts; Thiazoles | 2004 |
Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2.
Topics: Animals; Caveolin 1; Caveolin 2; Caveolins; Cell Adhesion; Cell Line; Cells, Cultured; Coloring Agents; Cystic Fibrosis; Epithelial Cells; Immunoprecipitation; Lipid Metabolism; Lipids; Lung; Membrane Microdomains; Mice; Microscopy, Confocal; Microscopy, Electron; Phosphorylation; Pseudomonas; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA Interference; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Transforming growth factor (TGF)-beta1 releasing tricalcium phosphate/chitosan microgranules as bone substitutes.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Bone Substitutes; Calcium Phosphates; Cell Differentiation; Cell Proliferation; Cell Survival; Chitosan; Mice; Microscopy, Electron, Scanning; Microspheres; Osteocalcin; Powders; Tetrazolium Salts; Thiazoles; Tissue Engineering; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Effects of extracts of commonly consumed food supplements and food fractions on the permeability of drugs across Caco-2 cell monolayers.
Topics: Biological Transport, Active; Caco-2 Cells; Cell Membrane Permeability; Dietary Supplements; Food; Fruit; Humans; Pharmaceutical Preparations; Phenols; Plant Extracts; Solvents; Tetrazolium Salts; Thiazoles | 2004 |
Synergistic cytotoxicity of acidity and glucose degradation products in peritoneal dialysis fluid.
Topics: Cell Survival; Cells, Cultured; Dialysis Solutions; Epithelial Cells; Hot Temperature; Hydrogen-Ion Concentration; Peritoneal Dialysis; Peritoneum; Tetrazolium Salts; Thiazoles | 2004 |
UW is superior to Celsior and HTK in the protection of human liver endothelial cells against preservation injury.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Cells, Cultured; Coloring Agents; Cryopreservation; Cytoprotection; Disaccharides; Electrolytes; Endothelial Cells; Glucose; Glutamates; Glutathione; Histidine; Humans; Insulin; L-Lactate Dehydrogenase; Liver; Mannitol; Organ Preservation Solutions; Potassium Chloride; Preservation, Biological; Procaine; Raffinose; Tetrazolium Salts; Thiazoles | 2004 |
The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Coloring Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Remission Induction; Sex Factors; Tetrazolium Salts; Thiazoles; Vincristine | 2004 |
Fibroblast growth factor receptors as molecular targets in thyroid carcinoma.
Topics: Adenoviridae; Animals; Blotting, Western; Carcinoma; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; Mice; Mice, SCID; Neoplasm Transplantation; Protein-Tyrosine Kinases; Pyrimidines; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Receptor, Fibroblast Growth Factor, Type 4; Receptors, Fibroblast Growth Factor; Signal Transduction; Tetrazolium Salts; Thiazoles; Thyroid Gland; Thyroid Neoplasms; Time Factors | 2005 |
The role of poly (adenosine 5'-diphosphate-ribose) polymerase in the response of pituitary tumor cells to reactive oxygen species.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Niacinamide; Oxidants; Pituitary Neoplasms; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Umbilical Veins | 2005 |
Anti-tumor activity of an enzymatically synthesized alpha-1,6 branched alpha-1,4-glucan, glycogen.
Topics: Amylose; Antineoplastic Agents; Glucans; Glycogen; Humans; Indicators and Reagents; Neoplasms, Experimental; Nitric Oxide; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2004 |
Propofol attenuates peroxynitrite-mediated DNA damage and apoptosis in cultured astrocytes: an alternative protective mechanism.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Astrocytes; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Comet Assay; DNA; DNA Damage; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; L-Lactate Dehydrogenase; Molsidomine; Oxidative Stress; Peroxynitrous Acid; Propofol; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2004 |
Cotargeting tumor and tumor endothelium effectively inhibits the growth of human prostate cancer in adenovirus-mediated antiangiogenesis and oncolysis combination therapy.
Topics: Adenocarcinoma; Adenoviridae; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Endothelial Cells; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Microscopy, Confocal; Neoplasm Metastasis; Neovascularization, Pathologic; Osteocalcin; Promoter Regions, Genetic; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Vascular Endothelial Growth Factor Receptor-2 | 2005 |
Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.
Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Humans; Membrane Potentials; Microscopy, Confocal; Minocycline; N-Methylaspartate; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2004 |
Bone marrow stromal cell-derived growth inhibitor inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis.
Topics: Amino Acid Sequence; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Blotting, Northern; Blotting, Western; Bone Marrow Cells; Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cyclin A; Cyclin-Dependent Kinase Inhibitor p27; DNA, Complementary; Down-Regulation; Gene Library; Genetic Vectors; HeLa Cells; Humans; Molecular Sequence Data; Phylogeny; Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; S Phase; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetrazolium Salts; Thiazoles; Tissue Distribution; Transfection; Tumor Suppressor Proteins; Up-Regulation; Wound Healing | 2005 |
In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.
Topics: Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Drug Resistance; Fibroblasts; Gossypol; Head and Neck Neoplasms; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Peptide Fragments; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2004 |
A novel neurotrophic peptide: APP63-73.
Topics: Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Line, Tumor; Cell Size; Cell Survival; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; L-Lactate Dehydrogenase; Male; Maze Learning; Mice; Nerve Growth Factors; Neuroblastoma; Ovariectomy; Peptide Fragments; Peptides; Random Allocation; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Adenylosuccinate lyase deficiency: study of physiopathologic mechanism(s).
Topics: Adenylosuccinate Lyase; Animals; Calcium; Cells, Cultured; Fibroblasts; Humans; Neurons; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Rats; Rats, Wistar; Skin; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Immunocytochemical detection of deoxycytidine kinase in pediatric malignancies in relation to in vitro cytarabine sensitivity.
Topics: Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Cell Line, Tumor; Coloring Agents; Cytarabine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Leukemia; Neoplasms; Retinoblastoma; Tetrazolium Salts; Thiazoles | 2004 |
Modulation of cytarabine induced cytotoxicity using novel deoxynucleoside analogs in the HL60 cell line.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Cladribine; Coloring Agents; Cytarabine; Deoxycytidine; DNA; Gemcitabine; HL-60 Cells; Humans; Inhibitory Concentration 50; Nucleosides; Tetrazolium Salts; Thiazoles; Vidarabine | 2004 |
The endogenous growth hormone secretagogue (ghrelin) is synthesized and secreted by chondrocytes.
Topics: Animals; Blotting, Southern; Boron Compounds; Cartilage; Cells, Cultured; Chondrocytes; Cyclic AMP; DNA Primers; Dose-Response Relationship, Drug; Fatty Acids; Flow Cytometry; Ghrelin; Humans; Immunohistochemistry; Kinetics; Mice; Peptide Hormones; Peptides; Protein Binding; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Interaction between the interferon signaling pathway and the human glucocorticoid receptor gene 1A promoter.
Topics: Amino Acid Motifs; Apoptosis; Blotting, Western; Cell Line; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Exons; Flow Cytometry; Genes, Reporter; Glucocorticoids; Humans; Interferon-gamma; Interferons; Jurkat Cells; L-Lactate Dehydrogenase; Luciferases; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transfection; Up-Regulation | 2005 |
Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia.
Topics: Alkenes; Antineoplastic Agents, Phytogenic; Brassicaceae; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Tetrazolium Salts; Thiazoles | 2004 |
A new cytotoxic naphthoquinone from Paepalanthus latipes.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Eriocaulaceae; Humans; Magnetic Resonance Spectroscopy; Naphthoquinones; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2004 |
CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway.
Topics: Caco-2 Cells; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Separation; Chemotaxis; Colon; Coloring Agents; Cytokines; Epithelial Cells; Flow Cytometry; Humans; Inflammation; Interleukin-8; Intestinal Mucosa; Mucous Membrane; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta | 2005 |
Cytotoxicity evaluation of gutta-percha solvents: Chloroform and GP-Solvent (limonene).
Topics: Animals; Cell Line; Cell Survival; Chloroform; Coloring Agents; Cyclohexenes; Dose-Response Relationship, Drug; Fibroblasts; Gutta-Percha; Limonene; Materials Testing; Mice; Solvents; Terpenes; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Evaluation of cellular toxicity of TAFMAG, a natural substitute for asbestos from China.
Topics: Animals; Asbestos, Serpentine; Cell Line; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Epithelial Cells; Erythrocyte Membrane; Erythrocytes; Hemolysis; Hydrogen Peroxide; In Vitro Techniques; Iron; Iron Chelating Agents; Lipid Peroxidation; Mineral Fibers; Particle Size; Pulmonary Alveoli; Rats; Silicates; Tetrazolium Salts; Thiazoles | 2005 |
Mercury induces multidrug resistance-associated protein gene through p38 mitogen-activated protein kinase.
Topics: Blotting, Western; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Chemokines, CC; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Imidazoles; Mercury; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2005 |
MgSO4 and lazaroid (U-83836E) partially protects glioma cells against glutamate toxicity in vitro.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Dose-Response Relationship, Drug; Drug Interactions; Glioma; Glutamic Acid; Humans; Inhibitory Concentration 50; Magnesium Sulfate; Mice; Neuroglia; Piperazines; Tetrazolium Salts; Thiazoles | 2004 |
Inconsistent role of nitric oxide on lipolysis in isolated rat adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bucladesine; Bupranolol; Cell Separation; Cells, Cultured; Cyclic AMP; Ethanolamines; In Vitro Techniques; Lipolysis; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Donors; Proteins; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Differential induction of podocyte heat shock proteins by prolonged single and combination toxic metal exposure.
Topics: Animals; Arsenites; Blotting, Western; Cadmium; Cell Survival; Cells, Cultured; Crystallins; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Kidney; Mercury; Metals; Mice; Phosphorylation; Tetrazolium Salts; Thiazoles | 2005 |
Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L.
Topics: Adenoviridae; Animals; Cell Line; Cell Proliferation; Coloring Agents; Glutathione Transferase; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; Immunoprecipitation; Leucine; Microscopy, Fluorescence; Mutation; Neurilemmoma; Neurofibromatosis 2; Neurofibromin 2; Phosphatidylinositol 3-Kinases; Point Mutation; Protein Binding; Rats; RNA Interference; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth.
Topics: Adenoviridae; Agar; Animals; Apoptosis; Baculoviridae; Cell Death; Cell Line; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Drosophila; Gene Deletion; Gene Expression Regulation; Genes, Reporter; Glutathione Transferase; Green Fluorescent Proteins; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; I-kappa B Proteins; Immunoprecipitation; Lentivirus; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Mutation; Neoplasm Transplantation; NF-kappa B; Osteosarcoma; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2005 |
Cytotoxicity of thermosensitive polymers poly(N-isopropylacrylamide), poly(N-vinylcaprolactam) and amphiphilically modified poly(N-vinylcaprolactam).
Topics: Acrylic Resins; Caco-2 Cells; Calorimetry, Differential Scanning; Caprolactam; Cell Line; Cell Line, Tumor; Cell Survival; Chromatography; Coloring Agents; Dose-Response Relationship, Drug; Hot Temperature; Humans; L-Lactate Dehydrogenase; Light; Models, Chemical; Polyethylene Glycols; Polymers; Scattering, Radiation; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2005 |
Self-curing controlled release systems for steroids. Application of prednisolone-based polymeric systems to ear diseases.
Topics: Animals; Benzoyl Peroxide; Biocompatible Materials; Coloring Agents; Diffusion; Drug Carriers; Drug Delivery Systems; Ear Diseases; Glucocorticoids; Humans; Kinetics; Methylmethacrylates; Microscopy, Electron; Models, Chemical; Oxidation-Reduction; Polymers; Polymethyl Methacrylate; Prednisolone; Steroids; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Antitumor and neurotoxic effects of novel harmine derivatives and structure-activity relationship analysis.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Lewis Lung; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA; fas Receptor; Flow Cytometry; Harmine; Humans; Immunoblotting; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Models, Chemical; Monoamine Oxidase Inhibitors; Neoplasm Transplantation; Peganum; Proto-Oncogene Proteins c-bcl-2; Sarcoma; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Bilirubin induces apoptosis and necrosis in human NT2-N neurons.
Topics: Apoptosis; Bilirubin; Cell Line; Cell Line, Tumor; Cell Nucleus; Coloring Agents; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; L-Lactate Dehydrogenase; Necrosis; Neurons; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Adenovirus-mediated p53 gene therapy in pediatric soft-tissue sarcoma cell lines: sensitization to cisplatin and doxorubicin.
Topics: Adenoviridae; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Doxorubicin; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Humans; In Situ Nick-End Labeling; Mutation; Prognosis; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma; RNA, Messenger; Sarcoma; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Biophysical and biochemical properties of a binary lipid mixture for DNA transfection.
Topics: Animals; beta-Galactosidase; Biocompatible Materials; Cations; DNA; Gene Transfer Techniques; Lipids; Liposomes; Macromolecular Substances; Mice; Microscopy, Fluorescence; NIH 3T3 Cells; Phosphatidylcholines; Plasmids; Pressure; Scattering, Radiation; Surface Properties; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Transfection; X-Rays | 2005 |
Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation.
Topics: Apoptosis; Bromodeoxyuridine; Caspases; Cell Hypoxia; Cell Survival; Cyclin-Dependent Kinases; Cytochromes c; DNA; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; G1 Phase; G2 Phase; Genes, myc; Growth Inhibitors; Humans; Hypoxia; In Situ Nick-End Labeling; Neuroblastoma; Piperidines; Proto-Oncogene Mas; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Cytotoxicity of two concentrations of a dentine bonding agent on mouse 3T3 and human pulp fibroblast cell-lines.
Topics: 3T3 Cells; Animals; Cell Count; Cell Line; Cell Survival; Coloring Agents; Dental Pulp; Dentin-Bonding Agents; Dose-Response Relationship, Drug; Fibroblasts; Humans; Mice; Polymethacrylic Acids; Tetrazolium Salts; Thiazoles | 2004 |
Cytotoxic and membrane perturbation effects of a novel amyloid forming model peptide poly(leucine-glutamic acid).
Topics: Adenosine Triphosphatases; Amyloid; Amyloid beta-Peptides; Cell Membrane; Circular Dichroism; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Free Radicals; Glutamic Acid; Glutathione; Humans; Leucine; Lipid Bilayers; Lymphocytes; Membrane Microdomains; Microscopy, Fluorescence; Oxygen; Peptides; Polyglutamic Acid; Protein Binding; Protein Structure, Secondary; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
Early and delayed glutamate effects in rat primary cortical neurons. Changes in the subcellular distribution of protein kinase C isoforms and in intracellular calcium concentration.
Topics: Algorithms; Animals; Blotting, Western; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Isoenzymes; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2005 |
Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cloning, Molecular; Coloring Agents; Death-Associated Protein Kinases; Decitabine; DNA Fragmentation; DNA Methylation; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fas Ligand Protein; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Neoplasms; Membrane Glycoproteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Tumor Necrosis Factor-alpha | 2004 |
Gene trap mutagenesis-based forward genetic approach reveals that the tumor suppressor OVCA1 is a component of the biosynthetic pathway of diphthamide on elongation factor 2.
Topics: Adenosine Diphosphate; Animals; Base Sequence; Blotting, Southern; Blotting, Western; CHO Cells; Coloring Agents; Cricetinae; Diphtheria Toxin; DNA, Complementary; Dose-Response Relationship, Drug; Genes, Tumor Suppressor; Genetic Techniques; Histidine; Humans; Mice; Minor Histocompatibility Antigens; Molecular Sequence Data; Mutagenesis; Mutation; Peptide Elongation Factor 2; Phenotype; Plasmids; Polymerase Chain Reaction; Proteins; Retroviridae; Sequence Homology, Nucleic Acid; Tetrazolium Salts; Thiazoles; Toxins, Biological; Tumor Suppressor Proteins | 2005 |
Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines.
Topics: Androgen Antagonists; Androgens; Anilides; Blotting, Western; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; Genes, p53; Humans; Male; Nitriles; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA; Telomerase; Tetrazolium Salts; Thiazoles; Tosyl Compounds | 2005 |
4'-O-Alkyaloenin derivatives and their sulfates directed toward overcoming multidrug resistance in tumor cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Colorectal Neoplasms; Coloring Agents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glucosides; Humans; Liver Neoplasms; Sulfates; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
Intrinsic chemotherapy resistance to the tubulin-binding antimitotic agents in renal cell carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Humans; Immunohistochemistry; Inhibitory Concentration 50; Kidney; Kidney Neoplasms; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Paclitaxel; Phenotype; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Time Factors; Tubulin; Up-Regulation; Vinblastine; Vincristine | 2005 |
Activity staining of glutathione peroxidase after two-dimensional gel electrophoresis.
Topics: Animals; Cloning, Molecular; Coloring Agents; Cytosol; Dithiothreitol; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Mercaptoethanol; Methylphenazonium Methosulfate; Mice; Silver Staining; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles | 2004 |
Influence of molecular weight on oral absorption of water soluble chitosans.
Topics: Absorption; Administration, Oral; Animals; Caco-2 Cells; Cell Survival; Chemical Phenomena; Chemistry, Physical; Chitosan; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Intestinal Absorption; Male; Molecular Weight; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2005 |
Epidermal growth factor-induced proliferation requires down-regulation of Pax6 in corneal epithelial cells.
Topics: Animals; beta-Galactosidase; Blotting, Northern; Blotting, Western; Cell Lineage; Cell Proliferation; Coloring Agents; Cornea; Down-Regulation; Epidermal Growth Factor; Epithelial Cells; Eye Proteins; Homeodomain Proteins; Humans; Luciferases; MAP Kinase Signaling System; Paired Box Transcription Factors; PAX6 Transcription Factor; Promoter Regions, Genetic; Protein Binding; Rabbits; Repressor Proteins; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Sodium butyrate induces apoptosis in MSN neuroblastoma cells in a calcium independent pathway.
Topics: Apoptosis; Brain Neoplasms; Bucladesine; Butyrates; Calcium; Calcium Signaling; Cell Line, Tumor; DNA Fragmentation; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Tetrazolium Salts; Theophylline; Thiazoles | 2004 |
Effect of bradykinin on nitric oxide production, urea synthesis and viability of rat hepatocyte cultures.
Topics: Animals; Bradykinin; Cell Survival; Cells, Cultured; Coloring Agents; Enzyme Inhibitors; Fluorescein; Hepatocytes; Indicators and Reagents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Urea | 2005 |
Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
Topics: BRCA2 Protein; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Separation; Cell Survival; Coloring Agents; DNA Damage; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fanconi Anemia Complementation Group D2 Protein; Flow Cytometry; Green Fluorescent Proteins; Humans; Immunoblotting; Immunoprecipitation; Mitomycin; Mutation; Nuclear Proteins; Rad51 Recombinase; Radiation, Ionizing; Recombination, Genetic; RNA Interference; Tetrazolium Salts; Thiazoles | 2005 |
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Calcium; Cell Death; Cells, Cultured; Culture Media, Conditioned; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Kynurenic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schwann Cells; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Neuroprotection by pergolide against levodopa-induced cytotoxicity of neural stem cells.
Topics: Animals; Annexin A5; Antimetabolites; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cells, Cultured; Dopamine Agents; Flow Cytometry; Fluorescein-5-isothiocyanate; Levodopa; Mice; Neurons; Neuroprotective Agents; Pergolide; Stem Cells; Tetrazolium Salts; Thiazoles | 2004 |
Role of MAPK/ERK in neurotrophin-4 potentiation of necrotic neuronal death.
Topics: Animals; Butadienes; Cell Death; Cells, Cultured; Cyclosporine; Enzyme Activation; Flavonoids; Immunosuppressive Agents; L-Lactate Dehydrogenase; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nerve Growth Factors; Neurons; Nitriles; Phosphorylation; Tetrazolium Salts; Thiazoles | 2004 |
p73 beta-expressing recombinant adenovirus: a potential anticancer agent.
Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Dose-Response Relationship, Drug; Flow Cytometry; Gene Transfer Techniques; Genes, Tumor Suppressor; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Neoplasms; Nuclear Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2005 |
Human tumor cell growth inhibition by nontoxic anthocyanidins, the pigments in fruits and vegetables.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Colorimetry; Drug Screening Assays, Antitumor; Fruit; Humans; Pigments, Biological; Tetrazolium Salts; Thiazoles; Vegetables | 2005 |
Presence of CCK-A, B receptors and effect of gastrin and cholecystokinin on growth of pancreatobiliary cancer cell lines.
Topics: Biliary Tract Neoplasms; Cell Count; Cell Division; Cell Line, Tumor; Cholecystokinin; Gastrins; Hormone Antagonists; Humans; Pancreatic Neoplasms; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2005 |
High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.
Topics: Base Pair Mismatch; Cell Line; Cell Survival; DNA Damage; DNA Methylation; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Humans; Kinetics; Methylnitronitrosoguanidine; Microscopy, Fluorescence; O(6)-Methylguanine-DNA Methyltransferase; Phosphorylation; S Phase; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.
Topics: Amyloid; Amyloid beta-Peptides; Artifacts; Biopolymers; Cell Death; Cell Membrane Permeability; Cells, Cultured; Cerebral Cortex; Coloring Agents; Crystallization; Formazans; Humans; Islet Amyloid Polypeptide; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Models, Chemical; Neurons; Oxidation-Reduction; Peptide Fragments; Solubility; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2005 |
Evidence for functional nicotinic receptors on pancreatic beta cells.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Azocines; Bungarotoxins; Cell Separation; Cell Survival; Cells, Cultured; Humans; Insulin; Islets of Langerhans; Nicotine; Nicotinic Agonists; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2005 |
Altered transcriptional regulators in response to serum in immortalized lymphocytes from Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Blotting, Western; Case-Control Studies; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Culture Media, Serum-Free; DNA-Binding Proteins; E2F Transcription Factors; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Humans; Imidazoles; Lymphocyte Activation; Lymphocytes; Male; NF-kappa B; Phosphorylation; Serum; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2005 |
Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system.
Topics: Analysis of Variance; Cell Count; Cell Survival; Cells, Cultured; Culture Media; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Fibroblast Growth Factor 2; Humans; L-Lactate Dehydrogenase; Lipopolysaccharides; Microglia; Monocytes; Neuroblastoma; Nitrites; Recombinant Proteins; Temporal Lobe; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Protective effect of diallyl disulfide on oxidative stress-injured neuronally differentiated PC12 cells.
Topics: Allyl Compounds; Animals; Antihypertensive Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Count; Cell Differentiation; Cell Survival; Chromones; Cytochromes c; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluoresceins; Gene Expression Regulation; Glycogen Synthase Kinase 3; Hydrogen Peroxide; Indoles; Membrane Glycoproteins; Morpholines; Neurons; Oxidative Stress; PC12 Cells; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Trypan Blue | 2005 |
Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Cell Line; Chromatography, High Pressure Liquid; Cyclic AMP; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Humans; In Situ Hybridization; Male; Mass Spectrometry; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Reflex, Acoustic; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Tenascin; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Relationship between alpha 7 nAChR and apoptosis in human lymphocytes.
Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Bungarotoxins; Cells, Cultured; Humans; Hydrocortisone; Lymphocytes; Muscle, Skeletal; Nicotine; Nicotinic Antagonists; Oxidation-Reduction; Protein Subunits; Rats; Rats, Wistar; Receptors, Nicotinic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation | 2005 |
Effect of lesions of cerebellar fastigial nuclei on lymphocyte functions of rats.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Brain Diseases; Cell Death; Cell Proliferation; Cerebellar Nuclei; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flow Cytometry; Glutamic Acid; Hypothalamus; Kainic Acid; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Macrolides; Quinolines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Staining and Labeling; Tetrazolium Salts; Thiazoles; Time Factors; Urea | 2005 |
p-Quinone mediates 6-hydroxydopamine-induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p-quinone into melanin extracellularly.
Topics: Analysis of Variance; Animals; Antioxidants; Benzoquinones; Bisbenzimidazole; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Humans; Hydrogen Peroxide; Immunohistochemistry; Iron; L-Lactate Dehydrogenase; Melanins; Mesencephalon; Models, Biological; Neuroblastoma; Neurons; Oxidopamine; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2005 |
Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells.
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Blotting, Western; Brain; Cell Line, Tumor; Cell Survival; Culture Media, Serum-Free; Cytoplasm; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; In Vitro Techniques; Microscopy, Immunoelectron; Models, Biological; Neuroblastoma; Phosphorylation; rab5 GTP-Binding Proteins; Rats; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; tau Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Zinc; Zinc Sulfate | 2005 |
Selective cytotoxicity of ascochlorin in ER-negative human breast cancer cell lines.
Topics: Alkenes; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; Cytochromes c; DNA Damage; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Luciferases; Phenols; Plasmids; Receptors, Estrogen; Tetrazolium Salts; Thiazoles | 2005 |
Induction of antiviral state in fish cells by Japanese flounder, Paralichthys olivaceus, interferon regulatory factor-1.
Topics: Animals; Cell Extracts; Cell Line; Cytokines; Cytotoxicity Tests, Immunologic; DNA-Binding Proteins; Flounder; Interferon Regulatory Factors; Novirhabdovirus; Plasmids; Tetrazolium Salts; Thiazoles; Transcription Factors; Transfection; Viral Proteins; Virus Replication | 2005 |
Antileukemic activity and cellular metabolism of the aryl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07).
Topics: Animals; Antimetabolites, Antineoplastic; Biotransformation; Carboxylic Ester Hydrolases; Cell Division; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Dideoxynucleotides; Drug Resistance, Multiple; Embryo, Nonmammalian; Glutathione; Humans; Leukemia; Nucleosides; Paraoxon; Rhodamine 123; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tumor Stem Cell Assay; Zebrafish; Zidovudine | 2005 |
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bone Marrow Cells; Caspase 3; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Cisplatin; Clinical Trials as Topic; Cytochromes c; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Enzyme Activation; Farnesyltranstransferase; Flow Cytometry; Fluorouracil; G2 Phase; Gemcitabine; Homozygote; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Mice; Mice, SCID; Mitosis; Multiple Myeloma; Paclitaxel; Quinolones; Taxoids; Tetrazolium Salts; Thiazoles | 2005 |
Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; CHO Cells; Coloring Agents; Cricetinae; DNA; DNA-Binding Proteins; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; Humans; Immunoprecipitation; Kinetics; Milk Proteins; Mutation; Pertussis Toxin; Phosphorylation; Prognosis; Protein Binding; RNA, Small Interfering; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator | 2005 |
Pseudomonas aeruginosa lipopolysaccharide induction of keratinocyte proliferation, NF-kappa B, and cyclin D1 is inhibited by indomethacin.
Topics: Blotting, Western; Cell Line, Transformed; Cell Proliferation; Clone Cells; Cyclin D1; Genes, Reporter; Growth Inhibitors; Humans; I-kappa B Proteins; Indomethacin; Keratinocytes; Lipopolysaccharides; Luciferases; NF-kappa B; NF-KappaB Inhibitor alpha; Pseudomonas aeruginosa; Tetrazolium Salts; Thiazoles; Thymidine; Transfection | 2005 |
Increased expression of the major heat shock protein Hsp72 in human prostate carcinoma cells is dispensable for their viability but confers resistance to a variety of anticancer agents.
Topics: Adenoviridae; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coloring Agents; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Vectors; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Immunoblotting; Male; NF-kappa B; Oxidative Stress; Prostatic Neoplasms; Retroviridae; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Colorimetric lactate dehydrogenase (LDH) assay for evaluation of antiviral activity against bovine viral diarrhoea virus (BVDV) in vitro.
Topics: Animals; Antiviral Agents; Cattle; Cells, Cultured; Colorimetry; Diarrhea Viruses, Bovine Viral; Humans; Interferon Type I; L-Lactate Dehydrogenase; Recombinant Proteins; Ribavirin; Tetrazolium Salts; Thiazoles; Virus Replication | 2005 |
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cell Proliferation; Ceruloplasmin; CHO Cells; Coloring Agents; Copper; Cricetinae; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Glucose Transporter Type 1; HeLa Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Iron; Liver; Luciferases; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Nuclear Proteins; Oxygen; Procollagen-Proline Dioxygenase; Promoter Regions, Genetic; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transcription Factors; Transcription, Genetic; Transfection; Vascular Endothelial Growth Factor A | 2005 |
Platelet-rich plasma enhances human osteoblast-like cell proliferation and differentiation.
Topics: Alkaline Phosphatase; Blood Platelets; Bone Regeneration; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen Type I; Coloring Agents; Core Binding Factor alpha Subunits; DNA-Binding Proteins; Glycoproteins; Humans; Osteoblasts; Osteopontin; Osteoprotegerin; Osteosarcoma; Phosphoproteins; Plasma; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Transcription Factors; Wound Healing | 2005 |
No genotoxicity of a new nickel-free stainless steel.
Topics: Animals; Biocompatible Materials; CHO Cells; Chromosome Aberrations; Coloring Agents; Cricetinae; Cricetulus; Materials Testing; Mutagens; Mutation; Nickel; Salmonella typhimurium; Sister Chromatid Exchange; Stainless Steel; Tetrazolium Salts; Thiazoles | 2005 |
Effects of X-ray irradiation on the overexpression of HER-2/Erb-B2 on breast cancer cell lines.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Radiation; Humans; Immunohistochemistry; In Vitro Techniques; Neoplasm Metastasis; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Time Factors; Trastuzumab; Trypan Blue; X-Rays | 2004 |
Functional erythropoietin autocrine loop in melanoma.
Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Cobalt; Coloring Agents; Culture Media, Conditioned; Disease Progression; Dose-Response Relationship, Drug; Erythropoietin; Humans; Hypoxia; Immunohistochemistry; MAP Kinase Signaling System; Melanocytes; Melanoma; Membrane Potentials; Mitochondria; Phosphorylation; Receptors, Erythropoietin; Tetrazolium Salts; Thiazoles; Trypan Blue | 2005 |
Involvement of c-Jun N-terminal kinase activities in skeletal muscle differentiation.
Topics: Animals; Apoptosis; Blotting, Western; Cell Differentiation; Cell Line; Cell Survival; Creatine Kinase; Enzyme Activation; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Rats; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2004 |
Establishment and gene analysis of a cisplatin-resistant cell line, Sa-3R, derived from oral squamous cell carcinoma.
Topics: Biopsy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Coloring Agents; DNA, Complementary; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Male; Mouth Neoplasms; Multidrug Resistance-Associated Protein 2; Oligonucleotide Array Sequence Analysis; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2005 |
The assessment of the viability of the endospores of Rhinosporidium seeberi with MTT (3-[4, 5-dimethyl-2-thiazolyl]-2, 5-diphenyl-2H-tetrazolium bromide).
Topics: Evans Blue; Organometallic Compounds; Rhinosporidiosis; Rhinosporidium; Spores, Fungal; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2004 |
Mode of action of taurine as a neuroprotector.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cells, Cultured; Excitatory Amino Acid Antagonists; Glutamic Acid; Ion Channel Gating; L-Lactate Dehydrogenase; Membrane Potentials; Neurons; Neuroprotective Agents; Rats; Receptors, N-Methyl-D-Aspartate; Taurine; Tetrazolium Salts; Thiazoles | 2005 |
ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.
Topics: Adenoviridae; Animals; Apoptosis; Blotting, Western; Butadienes; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Immunohistochemistry; Male; MAP Kinase Kinase Kinase 5; Mitogen-Activated Protein Kinase 7; Neurons; Nitriles; p38 Mitogen-Activated Protein Kinases; Potassium Deficiency; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Effect of hyperthermia on the cytotoxicity of 4 chemotherapeutic agents currently used for the treatment of transitional cell carcinoma of the bladder: an in vitro study.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Combined Modality Therapy; Deoxycytidine; Epirubicin; Gemcitabine; Humans; Hyperthermia, Induced; Indolequinones; Mitomycin; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms | 2005 |
The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Down-Regulation; Female; Growth Differentiation Factor 15; Humans; Luciferases; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sulindac; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2005 |
Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences.
Topics: alpha-Defensins; Animals; Antigens, Bacterial; Bacterial Toxins; Female; Furin; Humans; Kinetics; Macrophages; MAP Kinase Kinase 3; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Signal Transduction; Spores, Bacterial; Survival Analysis; Tetrazolium Salts; Thiazoles | 2005 |
Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Animals; Blotting, Northern; Blotting, Western; Brain; Cell Count; Cells, Cultured; Cloning, Molecular; Dopamine; Drug Interactions; Female; Fluorescent Antibody Technique; Gene Frequency; Genotype; Haplotypes; Humans; Immunoprecipitation; Male; Mice; Middle Aged; Monophenol Monooxygenase; Neuroblastoma; Neurons; Parkinson Disease; Polymorphism, Genetic; Postmortem Changes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transduction, Genetic; Transfection | 2005 |
Effect of natural and synthetic estrogens on a549 lung cancer cells: correlation of chemical structures with cytotoxic effects.
Topics: Adenocarcinoma; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Estradiol Congeners; Estrogens, Non-Steroidal; Fluorescence; Humans; Lung Neoplasms; Phenols; Reproducibility of Results; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2005 |
Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity.
Topics: Cell Line; Cell Survival; Cells, Cultured; Chymotrypsin; Humans; Hydrogen Peroxide; Interferon-gamma; L-Lactate Dehydrogenase; Microglia; Monocytes; Neurotoxicity Syndromes; Serine Proteinase Inhibitors; Stimulation, Chemical; Subcellular Fractions; Temporal Lobe; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina.
Topics: Animals; Azoles; Benzene Derivatives; Calcium; Calcium Channels; Chalcogens; Chick Embryo; Dose-Response Relationship, Drug; Glutamic Acid; Isoindoles; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organometallic Compounds; Organoselenium Compounds; Retina; Tellurium; Tetrazolium Salts; Thiazoles | 2005 |
Microglia is activated by astrocytes in trimethyltin intoxication.
Topics: Animals; Astrocytes; Cell Communication; Cells, Cultured; Coculture Techniques; Hydrogen Peroxide; Lipopolysaccharides; Microglia; Microscopy, Phase-Contrast; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proteins; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds | 2005 |
3,4,5,3',5'-Pentabromo-2-(2'-hydroxybenzoyl)pyrrole: a potential lead compound as anti-Gram-positive and anti-biofilm agent.
Topics: Anti-Bacterial Agents; Biofilms; Drug Resistance, Bacterial; Gentian Violet; Gram-Positive Bacteria; Humans; Hydrocarbons, Brominated; Microbial Sensitivity Tests; Pyrroles; Tetrazolium Salts; Thiazoles | 2005 |
Comparison of biological activity of recombinant woodchuck interferon gamma and tumor necrosis factor alpha produced in baculovirus and Escherichia coli expression systems.
Topics: Animals; Antiviral Agents; Baculoviridae; Blotting, Western; Cell Line; Cloning, Molecular; Coloring Agents; Cytokines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fibroblasts; Genes, MHC Class I; Genetic Techniques; Genetic Vectors; Immunoblotting; Immunoglobulin G; Insecta; Interferon-gamma; Major Histocompatibility Complex; Marmota; Mice; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Binding Sites; Carrier Proteins; Cell Line; Cell Survival; COS Cells; DNA Damage; DNA, Complementary; Exons; Glutathione Transferase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HeLa Cells; Homeodomain Proteins; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Models, Biological; p21-Activated Kinases; Phosphorylation; Plasmids; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; RNA-Binding Proteins; src Homology Domains; Tetrazolium Salts; Thiazoles; Transfection; Two-Hybrid System Techniques | 2005 |
Cyclooxygenase-2 inhibitor SC-236 [4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1-pyrazol-1-l] benzenesulfonamide] suppresses nuclear factor-kappaB activation and phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase,
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Immunohistochemistry; Ionophores; JNK Mitogen-Activated Protein Kinases; Luciferases; Mast Cells; Membrane Proteins; Microscopy, Confocal; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stimulation, Chemical; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2005 |
YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo models.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Blotting, Western; Cell Movement; Cell Proliferation; Endothelial Cells; Endothelium, Vascular; Enzyme Activators; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Guanylate Cyclase; Humans; Indazoles; Longevity; Microtubules; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Vascular Endothelial Growth Factor A | 2005 |
Anti-proliferative and anti-leukemic activity of DDE46 (compound WHI-07), a novel bromomethoxylated arylphosphate derivative of zidovudine, and related compounds. Studies using human acute lymphoblastic leukemia cells and the zebrafish model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Proliferation; Dideoxynucleotides; Drug Screening Assays, Antitumor; Humans; Jurkat Cells; Leukemia; Magnetic Resonance Spectroscopy; Nephelometry and Turbidimetry; Prodrugs; Tetrazolium Salts; Thiazoles; Thymidine Monophosphate; Tubulin; Zebrafish; Zidovudine | 2005 |
Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis.
Topics: Animals; Animals, Newborn; Antibodies; Apoptosis; Blotting, Western; Brain-Derived Neurotrophic Factor; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Immunohistochemistry; N-Methylaspartate; Neurons; Potassium Chloride; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time; Time Factors | 2005 |
Nitric oxide and prostaglandin E2 synthesis inhibitory activities of diarylheptanoids from the barks of Alnus japonica steudel.
Topics: Alnus; Chromatography, Thin Layer; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diarylheptanoids; Dinoprostone; Interferon-gamma; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitric Oxide; Nitric Oxide Synthase; Plant Bark; Prostaglandin-Endoperoxide Synthases; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2005 |
Anti-estrogenic activity of lignans from Acanthopanax chiisanensis root.
Topics: Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eleutherococcus; Enzyme Induction; Estrogen Antagonists; Female; Humans; Lignans; Magnetic Resonance Spectroscopy; Phytoestrogens; Plant Roots; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2005 |
Scoparone from Artemisia capillaris inhibits the release of inflammatory mediators in RAW 264.7 cells upon stimulation cells by interferon-gamma Plus LPS.
Topics: Animals; Anti-Inflammatory Agents; Artemisia; Blotting, Western; Cell Line; Cell Survival; Coumarins; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2005 |
Induction of caspase-independent apoptosis in H9c2 cardiomyocytes by adriamycin treatment.
Topics: Amino Acid Chloromethyl Ketones; Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Myocytes, Cardiac; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Blue light induces mitochondrial DNA damage and free radical production in epithelial cells.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Centrifugation; DNA; DNA Damage; DNA Repair; DNA, Mitochondrial; Epithelial Cells; Free Radicals; Humans; Hydroxyl Radical; Light; Lipofuscin; Mitochondria; Oxygen; Oxygen Consumption; Polymerase Chain Reaction; Reactive Oxygen Species; Retina; Superoxides; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2005 |
Dexamethasone inhibits the HSV-tk/ ganciclovir bystander effect in malignant glioma cells.
Topics: Anti-Inflammatory Agents; Antiviral Agents; Apoptosis; bcl-X Protein; Blotting, Western; Brain Neoplasms; Bystander Effect; Cell Communication; Cell Line, Tumor; Cell Separation; Cell Survival; Coloring Agents; Connexin 43; Dexamethasone; Fas Ligand Protein; fas Receptor; Flow Cytometry; Ganciclovir; Gap Junctions; Genetic Therapy; Glioma; Humans; Inhibitor of Apoptosis Proteins; Membrane Glycoproteins; Models, Statistical; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Tumor Necrosis Factors | 2005 |
T-2 toxin immunotoxicity on human B and T lymphoid cell lines.
Topics: Annexin A5; Apoptosis; B-Lymphocytes; Bromodeoxyuridine; Caspase 3; Caspases; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Edible Grain; Food Contamination; Humans; T-2 Toxin; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2005 |
Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein.
Topics: Active Transport, Cell Nucleus; Animals; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Separation; COS Cells; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; Flow Cytometry; Gene Expression Regulation; Humans; Immunoblotting; Immunoprecipitation; Luciferases; Microscopy, Fluorescence; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Transport; Retinoblastoma Protein; Smad7 Protein; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Effect of RNA interference on Gal alpha 1,3 Gal expression in PIEC cells.
Topics: Animals; Chlorocebus aethiops; Colorimetry; Complement Activation; COS Cells; Disaccharides; DNA Primers; Endothelial Cells; Flow Cytometry; Fucosyltransferases; Galactosides; Galactosyltransferases; Gene Expression; Humans; Indoles; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Sus scrofa; Tetrazolium Salts; Thiazoles; Transfection; Transplantation, Heterologous | 2005 |
HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Biomarkers; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Coloring Agents; Drug Interactions; Drug Resistance, Neoplasm; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression Profiling; Humans; Lung Neoplasms; Paclitaxel; Potassium Channels, Voltage-Gated; Tetrazolium Salts; Thiazoles; Transfection; Vincristine | 2005 |
Effect of acute and chronic psychostimulant drugs on redox status, AP-1 activation and pro-enkephalin mRNA in the human astrocyte-like U373 MG cells.
Topics: Amino Acid Transport System X-AG; Amphetamine; Analysis of Variance; Astrocytes; Blotting, Western; Cell Line; Central Nervous System Agents; Cocaine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrophoretic Mobility Shift Assay; Enkephalins; Excitatory Amino Acid Transporter 2; Fluoresceins; Fos-Related Antigen-2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Oxidation-Reduction; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1; Transcription Factors | 2005 |
Iron protects astrocytes from 6-hydroxydopamine toxicity.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Adhesion Molecules; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Ferric Compounds; Flow Cytometry; Hydroxydopamines; Iron; Iron Chelating Agents; Junctional Adhesion Molecules; L-Lactate Dehydrogenase; PC12 Cells; Phenanthrolines; Rats; Rats, Wistar; Staining and Labeling; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
The immunomodulatory effects of the dimer of lysozyme (KLP-602) in carp (Cyprinus carpio L)--in vivo study.
Topics: Animals; B-Lymphocytes; Carps; Cell Proliferation; Cell Separation; Immunity, Cellular; Immunologic Factors; In Vitro Techniques; Injections, Intraperitoneal; Insecticides; Kidney; Lymphocytes; Mitogens; Muramidase; Phagocytes; Pyrethrins; Respiratory Burst; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2005 |
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium.
Topics: ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Blotting, Western; Caco-2 Cells; Cadmium Poisoning; Calcium Channel Blockers; Cell Survival; DNA; Drug Resistance, Multiple; Electrophoresis, Agar Gel; Fluoresceins; Fluorescent Dyes; Humans; L-Lactate Dehydrogenase; Neutral Red; Tetrazolium Salts; Thiazoles; Verapamil | 2005 |
Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines.
Topics: Animals; Annexin A5; Anti-Bacterial Agents; Antioxidants; Apoptosis; Carcinoma; Caspase 2; Caspase 3; Caspase 9; Caspases; Cattle; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Immunoblotting; Jurkat Cells; Lactoferrin; Leukemia; Lymphocytes; Membrane Potentials; Microscopy, Electron; Mitochondria; Oligopeptides; Phosphatidylserines; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
High ambient glucose is effect neutral on cell death and proliferation in human proximal tubular epithelial cells.
Topics: Antimetabolites; Apoptosis; Bromodeoxyuridine; Cell Death; Cell Line; Cell Proliferation; Cell Separation; Culture Media; Epithelial Cells; Flow Cytometry; Glucose; Humans; In Situ Nick-End Labeling; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Necrosis; Tetrazolium Salts; Thiazoles | 2005 |
Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity.
Topics: Apoptosis; Benzimidazoles; Blotting, Southern; Blotting, Western; Caspase 3; Caspases; Cell Count; Cell Line, Tumor; Cell Proliferation; Colorimetry; Cyclin D1; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidases; Etoposide; Gene Expression Regulation, Neoplastic; Glioma; Humans; Insulin-Like Growth Factor I; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides, Antisense; Receptor, IGF Type 1; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Autocrine activation of microglia by tumor necrosis factor-alpha.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Antibodies; Autocrine Communication; Blotting, Northern; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha | 2005 |
Suramin promotes proliferation and scattering of renal epithelial cells.
Topics: Animals; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; Female; Genes, src; Humans; Immunohistochemistry; Indicators and Reagents; Kidney; Kidney Tubules, Proximal; Phosphatidylinositol 3-Kinases; Rabbits; Signal Transduction; Suramin; Tetrazolium Salts; Thiazoles; Trypanocidal Agents | 2005 |
Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death.
Topics: alpha-Tocopherol; Animals; Benzimidazoles; Benzoxazines; Blotting, Northern; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Capsaicin; Cell Count; Cell Death; Cell Lineage; Dizocilpine Maleate; DNA, Single-Stranded; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Excitatory Amino Acid Agonists; Immunohistochemistry; In Situ Nick-End Labeling; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Ruthenium; Tetrazolium Salts; Thiazoles; TRPC Cation Channels | 2005 |
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Phosphorylation; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Modulation of protein tyrosine phosphatase activity alters the subunit assembly in native N-methyl-D-aspartate receptor complex.
Topics: Animals; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoprecipitation; In Vitro Techniques; Mass Spectrometry; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Tetrazolium Salts; Thiazoles; Tyrosine; Vanadates | 2005 |
Studies of the anticancer potential of plants used in Bangladeshi folk medicine.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Bangladesh; Drug Screening Assays, Antitumor; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Medicine, Traditional; Mice; Ovum; Plant Bark; Plant Extracts; Plant Roots; Plants, Medicinal; Sea Urchins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
Antioxidant activity and cytotoxicity of eight plants used in traditional Arab medicine in Israel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Arabia; Cell Membrane; Cell Respiration; Drug Screening Assays, Antitumor; Humans; Iron; Israel; L-Lactate Dehydrogenase; Lipid Peroxidation; Medicine, Traditional; Mitochondria; PC12 Cells; Plant Extracts; Rats; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
Tanshinone: an inhibitor of proliferation of vascular smooth muscle cells.
Topics: Abietanes; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Flow Cytometry; Male; Muscle, Smooth, Vascular; Phenanthrenes; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Cell viability of chitosan-containing semi-interpenetrated hydrogels based on PCL-PEG-PCL diacrylate macromer.
Topics: Acrylates; Animals; Biocompatible Materials; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Coloring Agents; Drug Delivery Systems; Fibroblasts; Hot Temperature; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Lactic Acid; Light; Mice; NIH 3T3 Cells; Nitrogen; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polymers; Polystyrenes; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays; Water | 2005 |
Low levels of ALS-linked Cu/Zn superoxide dismutase increase the production of reactive oxygen species and cause mitochondrial damage and death in motor neuron-like cells.
Topics: Amyotrophic Lateral Sclerosis; Blotting, Western; Cell Death; Cell Division; Cell Line; Cell Proliferation; Cell Survival; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Motor Neurons; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Effects of various man-made mineral fibers on cell apoptosis and viability.
Topics: Apoptosis; Cell Survival; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Humans; Indicators and Reagents; Macrophages; Microscopy, Electron, Scanning; Mineral Fibers; Monocytes; Nucleosomes; Tetrazolium Salts; Thiazoles; U937 Cells | 2005 |
Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo.
Topics: Acetylation; Animals; Animals, Newborn; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Cycle Proteins; Cell Growth Processes; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Dose-Response Relationship, Drug; Flow Cytometry; Glioma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Mice; Neoplasm Transplantation; Organ Culture Techniques; Peptides, Cyclic; Rats; Rats, Inbred F344; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Vorinostat | 2005 |
Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity.
Topics: alpha-Tocopherol; Amyloid beta-Protein Precursor; Analysis of Variance; Antioxidants; Blotting, Western; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; F2-Isoprostanes; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Neuroblastoma; Peptide Fragments; Protein Synthesis Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetracycline; Tetrazolium Salts; Thiazoles; Time Factors; Tocopherols | 2005 |
The hair growth promoting effect of Asiasari radix extract and its molecular regulation.
Topics: Alopecia; Animals; Cell Proliferation; Cell Survival; Cholestenone 5 alpha-Reductase; Cysteine; DNA Primers; Female; Hair; Hair Follicle; Humans; Keratinocytes; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Plant Extracts; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Vibrissae | 2005 |
The mechanism of manganese-induced inhibition of steroidogenesis in rat primary Leydig cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Cell Cycle; Flow Cytometry; In Vitro Techniques; Leydig Cells; Male; Manganese; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Steroids; Tetrazolium Salts; Thiazoles | 2005 |
Differential effects of diallyl disulfide on neuronal cells depend on its concentration.
Topics: Allyl Compounds; Animals; Apoptosis; Blotting, Western; Cell Differentiation; Cell Line; Cell Survival; Disulfides; Dose-Response Relationship, Drug; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Glycogen Synthase Kinase 3; Indoles; Lipid Peroxidation; Membrane Lipids; Mice; Mice, Inbred BALB C; Neurons; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; Trypan Blue | 2005 |
Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases.
Topics: alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Catalytic Domain; Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media; Dopamine; Humans; Immunohistochemistry; Insecta; Kinetics; Male; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Nerve Tissue Proteins; Nitric Oxide; Nitrites; Oxidopamine; Oxygen; Parkinson Disease; Protein Binding; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substantia Nigra; Synucleins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Development of a modified MTT assay for screening antimonial resistant field isolates of Indian visceral leishmaniasis.
Topics: Amphotericin B; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Drug Resistance; Humans; Leishmania donovani; Leishmaniasis, Visceral; Parasitic Sensitivity Tests; Phosphorylcholine; Tetrazolium Salts; Thiazoles | 2005 |
Calcium phosphate nanoparticles as a novel nonviral vector for efficient transfection of DNA in cancer gene therapy.
Topics: Animals; Antimetabolites; Calcium Phosphates; Carcinoma; DNA; DNA Primers; Flucytosine; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanostructures; Nasopharyngeal Neoplasms; Particle Size; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Studies on inducing apoptosis effects and mechanism of CIK cells for MGC-803 gastric cancer cell lines.
Topics: Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chromatin; Coculture Techniques; Cyclin-Dependent Kinase Inhibitor p16; Down-Regulation; Enzyme Inhibitors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Killer Cells, Natural; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Mitochondrial mediated thimerosal-induced apoptosis in a human neuroblastoma cell line (SK-N-SH).
Topics: Antifungal Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Line, Tumor; Cytochromes c; Humans; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Mitochondria; Neuroblastoma; Poly(ADP-ribose) Polymerases; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Thimerosal | 2005 |
Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion.
Topics: Adjuvants, Immunologic; Animals; beta Carotene; C-Reactive Protein; Complement Activation; Complement Inactivator Proteins; Complement Membrane Attack Complex; Erythrocytes; Fluorescent Antibody Technique; Hemodynamics; Hemolysis; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rabbits; Tetrazolium Salts; Thiazoles; Tissue Distribution; Troponin I; Xanthophylls | 2005 |
Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells.
Topics: Annexin A5; Antiparkinson Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Isatin; Monoamine Oxidase Inhibitors; Necrosis; Neuroblastoma; Neurons; Neurotoxins; Parkinson Disease; Propidium; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity.
Topics: Animals; Antibiotics, Antineoplastic; Area Under Curve; Buffers; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Humans; Hydrogen-Ion Concentration; Idarubicin; Liposomes; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pharmaceutical Vehicles; Polyethylene Glycols; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 2005 |
A study of the effects of phototherapy dose interval on photobiomodulation of cell cultures.
Topics: Animals; Cell Line; Cell Proliferation; Coloring Agents; Connective Tissue Cells; Dose Fractionation, Radiation; Epithelial Cells; Humans; Mice; Phototherapy; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Sphingosine 1-phosphate is involved in cytoprotective actions of calcitriol in human fibroblasts and enhances the intracellular Bcl-2/Bax rheostat.
Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Calcitriol; Cell Proliferation; Cell Survival; Cells, Cultured; Ceramides; DNA; Down-Regulation; Fibroblasts; Flow Cytometry; Genes, bcl-2; Humans; Immunoblotting; Lysophospholipids; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
5-aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Fibrosis; Flow Cytometry; Humans; Light; Melanoma; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Metastasis; Neoplasms, Experimental; NIH 3T3 Cells; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Trypan Blue | 2005 |
Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cytokines; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expression Profiling; Gene Expression Regulation; Glycoproteins; Hydroxamic Acids; Immunohistochemistry; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Neurons; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Spleen; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Effect of sesaminol glucosides on beta-amyloid-induced PC12 cell death through antioxidant mechanisms.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyloid beta-Peptides; Animals; Antioxidants; bcl-2-Associated X Protein; Blotting, Western; Calcium; Caspase 3; Caspases; Cell Death; Cell Survival; Deoxyguanosine; Dioxoles; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Furans; Glucosides; Humans; Hydrogen Peroxide; Indoles; Iron; Mitogen-Activated Protein Kinases; NF-kappa B; PC12 Cells; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfides; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2005 |
Evaluation of immunotherapy in invasive candidiasis: antifungal activity and cytokine expression assays.
Topics: Animals; Candida albicans; Candidiasis; Cell Separation; Chemokines; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Immunotherapy; In Vitro Techniques; Phagocytes; Phagocytosis; Rabbits; Respiratory Burst; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazolium Salts; Thiazoles | 2005 |
Anti-inflammatory activities of flavonoids isolated from Caesalpinia pulcherrima.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caesalpinia; Cells, Cultured; Female; Flavonoids; Indicators and Reagents; Interleukin-12; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitrites; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenoviridae; Animals; Apoptosis; Benzimidazoles; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Densitometry; Disease Progression; Enzyme Activation; Epithelial Cells; Fenretinide; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; Luciferases; Male; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Neoplasms; Neurons; Neurosecretory Systems; Phenotype; Plasmids; Prostate; Prostatic Neoplasms; Rats; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Synaptophysin; Tetrazolium Salts; Thiazoles; Tissue Distribution; Transcription Factors; Transcription, Genetic; Up-Regulation | 2005 |
Role of IL-6 in neuroendocrine differentiation and chemosensitivity of non-small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Differentiation; Cell Division; Cell Line, Tumor; Cisplatin; Coloring Agents; Down-Regulation; ErbB Receptors; Etoposide; Humans; Interleukin-6; Lung Neoplasms; Neurosecretory Systems; Phosphopyruvate Hydratase; Receptors, Interleukin-6; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Baclofen; Blotting, Western; Calcium; Calcium Channel Blockers; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; GABA Agonists; Glutamic Acid; Muscimol; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, GABA-A; Tetrazolium Salts; Thiazoles; Time Factors; Verapamil | 2005 |
Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia.
Topics: Analysis of Variance; Apoptosis; Astrocytes; Caspases; Cell Count; Cells, Cultured; Culture Media, Conditioned; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; Fetus; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Indoles; Interleukin-1; Intermediate Filament Proteins; Membrane Glycoproteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
The MTT assay to evaluate chemosensitivity.
Topics: Animals; Antineoplastic Agents; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Drug Evaluation, Preclinical; Humans; Immunologic Factors; Tetrazolium Salts; Thiazoles | 2005 |
Histoculture drug response assay to monitor chemoresponse.
Topics: Antineoplastic Agents; Biopsy; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Female; Gelatin; Gels; Humans; Ovarian Neoplasms; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2005 |
Proteomic analysis of anti-cancer effects by paclitaxel treatment in cervical cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Cycle Proteins; Electrophoresis, Gel, Two-Dimensional; Female; HeLa Cells; Humans; Paclitaxel; Poly-ADP-Ribose Binding Proteins; Proteomics; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transfection; Uterine Cervical Neoplasms | 2005 |
Biocompatible oligochitosans as cationic modifiers of alginate/Ca microcapsules.
Topics: Alginates; Animals; Biocompatible Materials; Calcium; Capsules; Cations; Cell Line; Cell Survival; Cells, Cultured; Chitin; Chitosan; Fibroblasts; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Materials Testing; Mice; Oligosaccharides; Osmosis; Permeability; Polysaccharides; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Low-level laser irradiation promotes proliferation and differentiation of human osteoblasts in vitro.
Topics: Alkaline Phosphatase; Biomarkers; Cell Count; Cell Differentiation; Cell Line; Cell Proliferation; Colorimetry; Coloring Agents; Humans; Immunohistochemistry; Integrin-Binding Sialoprotein; Low-Level Light Therapy; Osteoblasts; Osteogenesis; Osteopontin; Sialoglycoproteins; Tetrazolium Salts; Thiazoles | 2005 |
Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression.
Topics: Animals; Carbocyanines; Fluorometry; Integrins; Ligands; Mice; Mice, Nude; Microscopy, Fluorescence; Molecular Probe Techniques; Neoplasms; Oligopeptides; Peptides, Cyclic; Snake Venoms; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
Cytotoxic effects of a decoction of Nigella sativa, Hemidesmus indicus and Smilax glabra on human hepatoma HepG2 cells.
Topics: Annexin A5; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; DNA; Flow Cytometry; Hemidesmus; Humans; Leucine; Nigella; Plant Extracts; Seeds; Smilax; Tetrazolium Salts; Thiazoles; Thymidine | 2005 |
116 kDa glycoprotein isolated from Ulmus davidiana Nakai (UDN) inhibits glucose/glucose oxidase (G/GO)-induced apoptosis in BNL CL.2 cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Catalase; Cell Line; Cell Nucleus; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glucose; Glucose Oxidase; Glycoproteins; Mice; NF-kappa B; Nitric Oxide; Poly(ADP-ribose) Polymerase Inhibitors; Tetrazolium Salts; Thiazoles; Ulmus | 2005 |
Protective effects of baicalein on tert-butyl hydroperoxide-induced hepatic toxicity in rat hepatocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Animals; Antioxidants; Cells, Cultured; Deoxyguanosine; DNA; DNA Damage; DNA Repair; Flavanones; Free Radicals; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Membrane Potentials; Mitochondria; Models, Chemical; Oxidative Stress; Protective Agents; Rats; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 2005 |
Cytotoxicity, antitumoral and antimycobacterial activity of tetrazole and oxadiazole derivatives.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Humans; Mycobacterium; Oxadiazoles; Structure-Activity Relationship; Tetrazoles; Tetrazolium Salts; Thiazoles | 2005 |
Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells.
Topics: Animals; Antimetabolites; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Differentiation; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Female; Immunohistochemistry; In Situ Nick-End Labeling; Interferon-gamma; L-Lactate Dehydrogenase; Myelin Sheath; Oligodendroglia; Platelet-Derived Growth Factor; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Tetrazolium Salts; Thiazoles; Thyroid Hormones | 2005 |
Cytotoxic and genotoxic effects of tert-butyl hydroperoxide on Chinese hamster B14 cells.
Topics: Analysis of Variance; Animals; Cell Membrane; Cell Proliferation; Cell Survival; Cells, Cultured; Comet Assay; Cricetinae; Cricetulus; DNA Damage; Dose-Response Relationship, Drug; Fluorescence Polarization; Glutathione; Hypochlorous Acid; Lipid Peroxidation; Potassium; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 2005 |
Immunosuppressive immunophilin ligands attenuate damage in cultured rat astrocytes depleted of glutathione and exposed to simulated ischemia in vitro. Comparison with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Benzimidazoles; Brain Ischemia; Cell Separation; Cells, Cultured; Cyclosporine; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Immunophilins; Immunosuppressive Agents; Ligands; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tacrolimus; Tetrazolium Salts; Thiazoles | 2005 |
Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kappaB and caspase-3.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Caspase 3; Caspases; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Electrophoretic Mobility Shift Assay; Enzyme Activation; Granulocyte Precursor Cells; HL-60 Cells; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Poly(ADP-ribose) Polymerases; Protein Transport; Scopoletin; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Glioblastoma; Half-Life; Humans; Indicators and Reagents; Interferons; Janus Kinase 1; Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger; STAT1 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Trans-Activators; Transcriptional Activation; Up-Regulation | 2005 |
Antioxidant activity and antiproliferative action of methanolic extract of Geum quellyon Sweet roots in human tumor cell lines.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Caco-2 Cells; Cell Line, Tumor; Chelating Agents; Chile; Comet Assay; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Free Radical Scavengers; Geum; Humans; Hydrazines; Hydrogen Peroxide; KB Cells; L-Lactate Dehydrogenase; Male; Medicine, Traditional; Picrates; Plant Extracts; Plant Roots; Prostatic Neoplasms; Reactive Oxygen Species; Tannins; Tetrazolium Salts; Thiazoles; Ultraviolet Rays; Xanthine Oxidase | 2005 |
Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells.
Topics: Animals; Antigens, CD34; Apoptosis; Blotting, Western; Bone Marrow Cells; Caspase 3; Caspases; Cell Adhesion; Cell Cycle; Cell Nucleus; Cell Proliferation; Cell Separation; Coloring Agents; Eflornithine; Femur; Flow Cytometry; In Situ Nick-End Labeling; Leukocyte Common Antigens; Leupeptins; Microscopy, Fluorescence; Ornithine Decarboxylase; Osteocytes; Polyamines; Proteasome Inhibitors; Putrescine; Rats; Rats, Wistar; Spermidine; Stromal Cells; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2005 |
Theophylline stimulates cAMP-mediated signaling associated with growth regulation in human cells from pulmonary adenocarcinoma and small airway epithelia.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Epithelial Cells; Humans; Immunoassay; Lung Neoplasms; MAP Kinase Signaling System; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphorylation; Signal Transduction; Tetrazolium Salts; Theophylline; Thiazoles; Time Factors; Trachea | 2005 |
The evaluation of cytotoxic activity of planar pentadentate ligand 2',2"'-(2,6-pyridindiyldiethylidyne) dioxamohydrazide dihydrate (H2l x 2H2O) and its metal coordination complexes; pitfalls in the use of the MTT-assay.
Topics: Cell Line, Tumor; Cell Survival; Cobalt; Copper; Formazans; Humans; Hydrazines; Inhibitory Concentration 50; Iron; Ligands; Molecular Structure; Pyridines; Tetrazolium Salts; Thiazoles | 2005 |
A continuous spectrophotometric assay for NADPH-cytochrome P450 reductase activity using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.
Topics: Animals; Ferricyanides; Kinetics; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2005 |
N4,N9-dioleoyl spermine is a novel nonviral lipopolyamine vector for plasmid DNA formulation.
Topics: Cell Line, Tumor; Chemistry, Pharmaceutical; DNA; Escherichia coli; Ethidium; Excipients; Fluorescent Dyes; Genetic Vectors; Green Fluorescent Proteins; Humans; Light; Liposomes; Plasmids; Scattering, Radiation; Spermine; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Female; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2005 |
p16 tumor suppressor therapy in salivary adenoid cystic carcinoma cell line SACC83.
Topics: Carcinoma, Adenoid Cystic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA; Flow Cytometry; Genes, p16; Genetic Therapy; Humans; Linear Models; Reverse Transcriptase Polymerase Chain Reaction; Salivary Gland Neoplasms; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Different responses by cultured aortic and venous smooth muscle cells to gamma radiation.
Topics: Antimetabolites; Aorta; Bromodeoxyuridine; Cell Count; Cell Division; Cells, Cultured; Coloring Agents; Gamma Rays; Graft Occlusion, Vascular; Humans; Muscle, Smooth, Vascular; Saphenous Vein; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 2005 |
Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; ErbB Receptors; Flow Cytometry; Gefitinib; Humans; Immunoblotting; Inhibitory Concentration 50; Lung Neoplasms; Models, Statistical; Polymerase Chain Reaction; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2005 |
Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; DNA; DNA Mutational Analysis; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Gene Duplication; Gene Rearrangement; Humans; Immunoprecipitation; In Situ Hybridization, Fluorescence; Infant; Infant, Newborn; Ligands; Mutation; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sequence Analysis, DNA; Staurosporine; Tetrazolium Salts; Thiazoles | 2005 |
Effects of methylmercury on primary brain cells in mono- and co-culture.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Coculture Techniques; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Methylmercury Compounds; Mice; Neurons; Tetrazolium Salts; Thiazoles | 2005 |
TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism.
Topics: Adenoviridae; Apoptosis; bcl-X Protein; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Coloring Agents; Enzyme Inhibitors; Genes, Dominant; Humans; Immunoprecipitation; Mutation; Neuroblastoma; Neurons; Prognosis; Proto-Oncogene Proteins c-bcl-2; Receptor, trkA; Receptor, trkB; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Effects of anthocyanidin on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells.
Topics: Adenocarcinoma; Anthocyanins; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Flow Cytometry; Humans; Membrane Potentials; Microscopy, Phase-Contrast; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2005 |
Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions.
Topics: Animals; Calcium; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Membrane Potentials; Minocycline; Mitochondria; Mitochondrial Swelling; NADP; Neuroblastoma; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spectrophotometry; Staurosporine; Tetrazolium Salts; Thiazoles | 2005 |
Electrochemical genosensing of the interaction between the potential chemotherapeutic agent, cis-bis(3-aminoflavone)dichloroplatinum(II) and DNA in comparison with cis-DDP.
Topics: Adenine; Antineoplastic Agents; Cisplatin; DNA; Electrochemistry; Electrodes; Graphite; Organoplatinum Compounds; Oxidation-Reduction; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 2005 |
Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
Topics: Amlodipine; Analysis of Variance; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Therapy; Flow Cytometry; Fluorescence; Humans; K562 Cells; Neoplasms; Rhodamine 123; Tetrazolium Salts; Thiazoles; Time Factors; Verapamil | 2005 |
Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia.
Topics: Alitretinoin; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebral Cortex; Chemokines; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Nitric Oxide; Peroxisome Proliferators; PPAR alpha; Retinoid X Receptors; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Necrosis Factor-alpha | 2005 |
GABAA receptor-associated protein (GABARAP) induces apoptosis by interacting with DEAD (Asp-Glu-Ala-Asp/His) box polypeptide 47 (DDX 47).
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Cell Line, Tumor; Chromatography, Liquid; DEAD-box RNA Helicases; DNA, Complementary; Glutathione Transferase; Humans; Immunoprecipitation; Mass Spectrometry; Microtubule-Associated Proteins; Neurons; Protein Binding; Recombinant Fusion Proteins; RNA Helicases; Tetrazolium Salts; Thiazoles; Two-Hybrid System Techniques | 2005 |
Susceptibility of DNA to oxidative stressors in young and aging mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Carbon Tetrachloride; Cells, Cultured; Chromatography, High Pressure Liquid; Comet Assay; Deoxyguanosine; DNA Damage; Female; Hydrogen Peroxide; Liver; Mice; Mice, Mutant Strains; Oxidative Stress; Reactive Oxygen Species; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2005 |
Relationship between constitutive nuclear factor-kappaB (NF-kappaB) and inhibitor kappaB-alpha (IkappaB-alpha) in an interferon-alpha-sensitive human Burkitt lymphoma cell line.
Topics: Apoptosis; Blotting, Western; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Collagen Type XI; Electrophoretic Mobility Shift Assay; Humans; I-kappa B Proteins; Interferon-alpha; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Protein p53 | 2005 |
Effects of human Na(+)/dicarboxylate cotransporter 3 on the replicative senescence of human embryonic lung diploid fibroblasts.
Topics: Blotting, Northern; Blotting, Western; Cell Cycle; Cellular Senescence; Dicarboxylic Acid Transporters; Diploidy; Fibroblasts; Genetic Vectors; Humans; Lung; Organic Anion Transporters, Sodium-Dependent; Symporters; Telomere; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines.
Topics: Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Cytokines; DNA, Complementary; Humans; Hydrogen Peroxide; Insulin; Interferon-gamma; Interleukin-1; Mitochondria; Oxidants; Reactive Oxygen Species; RNA, Antisense; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Vitamin K 3 | 2005 |
Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against beta-amyloid-induced toxicity.
Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Analysis of Variance; Animals; Cell Survival; Chromatography, Thin Layer; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Free Radicals; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Phytoestrogens; Piperazines; Plant Preparations; Rats; Tetrazolium Salts; Thiazoles | 2005 |
S-2474, a novel nonsteroidal anti-inflammatory drug, rescues cortical neurons from human group IIA secretory phospholipase A(2)-induced apoptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbamates; Cell Count; Cell Size; Cells, Cultured; Cerebral Cortex; Chromatin; Cyclic S-Oxides; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Group II Phospholipases A2; Humans; In Situ Nick-End Labeling; Indolizines; Neurons; Phospholipases A; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2005 |
Effect of endogenous catecholamines in lymphocytes on lymphocyte function.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; alpha-Methyltyrosine; Analysis of Variance; Animals; Blotting, Northern; Catecholamines; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Concanavalin A; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; Lymphocyte Activation; Lymphocytes; Pargyline; Phentolamine; Propranolol; Radioimmunoassay; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2005 |
Cationic niosomes as gene carriers: preparation and cellular uptake in vitro.
Topics: Animals; Cations; Chlorocebus aethiops; COS Cells; DNA; Drug Compounding; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Excipients; Gene Transfer Techniques; Membranes, Artificial; Microspheres; Particle Size; Tetrazolium Salts; Thiazoles | 2005 |
Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Cerebral Cortex; Cloning, Molecular; Dose-Response Relationship, Drug; Flow Cytometry; Gene Products, tat; Glutamic Acid; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Lactate Dehydrogenases; Neurons; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2005 |
Protein bonding on biodegradable poly(L-lactide-co-caprolactone) membrane for esophageal tissue engineering.
Topics: Acetamides; Animals; Binding Sites; Biocompatible Materials; Caproates; Cell Culture Techniques; Cell Line; Cell Movement; Cells, Cultured; Collagen; DNA; Electron Probe Microanalysis; Endothelial Cells; Esophagus; Fibroblasts; Fibronectins; Glutaral; Lactones; Microscopy, Electron, Scanning; Mitochondria; Polyesters; Proteins; Surface Properties; Swine; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2006 |
Sensitivity of human cord blood cells to tetrachloroethylene: cellular and molecular endpoints.
Topics: Apoptosis; Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Erythroid Precursor Cells; Fetal Blood; Flow Cytometry; Genes, Tumor Suppressor; Humans; In Vitro Techniques; Neoplasms; Oligonucleotide Array Sequence Analysis; Oncogenes; Reverse Transcriptase Polymerase Chain Reaction; RNA; Solvents; Tetrachloroethylene; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Up-Regulation | 2005 |
Neuroactive steroids protect retinal pigment epithelium against oxidative stress.
Topics: Cell Count; Cell Survival; Cells, Cultured; Dehydroepiandrosterone Sulfate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Ethylenediamines; Humans; Hydrogen Peroxide; Oxidative Stress; Pigment Epithelium of Eye; Tetrazolium Salts; Thiazoles | 2005 |
Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.
Topics: Animals; Apoptosis; Arsenites; Blotting, Western; Cell Survival; Cells, Cultured; DNA, Complementary; Electrophoretic Mobility Shift Assay; Fibroblasts; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Hydroquinones; Mice; Mice, Knockout; NF-kappa B; Oligonucleotide Array Sequence Analysis; Oxidants; Oxidative Stress; RNA; Tetrazolium Salts; Thiazoles | 2005 |
Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cytosol; Electrophoresis, Polyacrylamide Gel; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Neurons; Oxidative Stress; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles | 2005 |
Evaluation of cytotoxicity by flow cytometric drug sensitivity assay in childhood T-cell acute lymphoblastic leukemia.
Topics: Apoptosis; Bone Marrow Cells; Child; Daunorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Immunophenotyping; Inhibitory Concentration 50; Leukemia, T-Cell; Medical Oncology; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 2005 |
Competitive quenching: a possible novel approach in protecting RPE cells from damage during PDT.
Topics: Animals; Anthracenes; Cell Line; Cell Survival; Choroidal Neovascularization; Cytoprotection; Male; Oxidation-Reduction; Perylene; Photochemotherapy; Photosensitizing Agents; Pigment Epithelium of Eye; Porphyrins; Rabbits; Rats; Rats, Wistar; Retina; Tetrazolium Salts; Thiazoles; Verteporfin | 2005 |
Assessment of bovine sperm viability by MTT reduction assay.
Topics: Acrosome; Animals; Cattle; Cell Survival; Coloring Agents; Flow Cytometry; Male; Mitochondria; Oxidation-Reduction; Regression Analysis; Spermatozoa; Tetrazolium Salts; Thiazoles | 2006 |
Release characteristics and bioactivity of gelatin-tricalcium phosphate membranes covalently immobilized with nerve growth factors.
Topics: Animals; Biocompatible Materials; Calcium Phosphates; Carbodiimides; Cell Membrane; Cell Proliferation; Cell Size; Cell Survival; Cells, Cultured; Cross-Linking Reagents; Diffusion; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gelatin; Kinetics; L-Lactate Dehydrogenase; Models, Chemical; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Rats; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
An approach to As(III) and As(V) bioavailability studies with Caco-2 cells.
Topics: Arsenic; Biological Availability; Caco-2 Cells; Cell Survival; Electric Impedance; Humans; Intestinal Absorption; Intestinal Mucosa; Tetrazolium Salts; Thiazoles | 2005 |
Blood compatibility of thermoplastic polyurethane membrane immobilized with water-soluble chitosan/dextran sulfate.
Topics: Acrylic Resins; Adsorption; Animals; Blood Coagulation; Blood Group Antigens; Blood Platelets; Cell Proliferation; Cell Survival; Chitosan; Dextran Sulfate; Dose-Response Relationship, Drug; Fibrinogen; Fibroblasts; Glucose; Humans; Hydrogen-Ion Concentration; Macromolecular Substances; Mice; Models, Chemical; Ozone; Plastics; Platelet Adhesiveness; Polyurethanes; Spectrometry, X-Ray Emission; Surface Properties; Tetrazolium Salts; Thiazoles; Thrombosis; Time Factors; Water | 2005 |
[131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice.
Topics: Animals; Cell Hypoxia; Cell Proliferation; Female; Humans; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Nitroimidazoles; Radioimmunotherapy; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; Tissue Distribution; Tumor Cells, Cultured | 2005 |
Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Ceramides; Cerebral Cortex; Chromatography, Thin Layer; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Green Fluorescent Proteins; Infections; Mutagenesis; Neurons; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oligodendroglia; Peptide Fragments; Radioligand Assay; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingomyelin Phosphodiesterase; Stem Cells; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Effect of different zinc sources and levels on inhibition of the apoptosis induced by glucocorticoid of thymocytes in vitro.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Cell Nucleus; Coloring Agents; Dexamethasone; Dietary Supplements; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Glucocorticoids; In Vitro Techniques; Mice; Mice, Inbred ICR; Oxidation-Reduction; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thymus Gland; Time Factors; Zinc; Zinc Compounds; Zinc Sulfate | 2005 |
Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes.
Topics: Animals; Blotting, Western; Ear Neoplasms; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Melanocytes; Melanoma; Melanoma, Experimental; Membrane Glycoproteins; Mice; Mice, Transgenic; Oxidoreductases; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2005 |
Low shrinkage light curable nanocomposite for dental restorative material.
Topics: Coloring Agents; Composite Resins; Cyclohexanecarboxylic Acids; Epoxy Resins; Hardness; Humans; Light; Materials Testing; Microscopy, Electron, Transmission; Nanostructures; Polymers; Silanes; Silicon Dioxide; Stress, Mechanical; Surface Properties; Temperature; Tensile Strength; Tetrazolium Salts; Thermodynamics; Thiazoles | 2006 |
Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.
Topics: Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Animals; Anions; Benzothiazoles; Biochemistry; Cell Line; Chromatography; Congo Red; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Light; Lysine; Magnetic Resonance Spectroscopy; Mice; Micelles; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Weight; Naphthalenesulfonates; Peptide Fragments; Peptides; Phenylalanine; Prions; Protein Structure, Secondary; Scattering, Radiation; Sodium Dodecyl Sulfate; Spectrophotometry; Static Electricity; Sulfonic Acids; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Role of GSK-3beta activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene.
Topics: Alanine; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; Collagen Type XI; Cytochromes c; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heat-Shock Proteins; Humans; Hybrid Cells; Indoles; Motor Neurons; Mutagenesis; Neuroblastoma; Phosphatidylinositol 3-Kinases; Point Mutation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Trypan Blue; Valine | 2005 |
Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia.
Topics: Animals; Blotting, Northern; Brain; Brain Ischemia; Calcium; Coloring Agents; Down-Regulation; Egtazic Acid; Genes, Reporter; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Luciferases; Microscopy, Fluorescence; Models, Biological; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
L-carnitine inhibits hypoglycemia-induced brain damage in the rat.
Topics: Aldehydes; Analysis of Variance; Animals; Apoptosis; Benzimidazoles; Brain Injuries; Carbocyanines; Carnitine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Glucose; Glutathione; Hippocampus; Hypoglycemia; Immunohistochemistry; In Situ Nick-End Labeling; Insulin; Male; Maze Learning; Membrane Potentials; Mitochondria; Neurons; Rats; Rats, Wistar; Reaction Time; Reactive Oxygen Species; Respiration; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Lipophilic toxicity from the marine dinoflagellate Karenia brevisulcata: use of the brevetoxin neuroblastoma assay to assess toxin presence and concentration.
Topics: Animals; Biological Assay; Cell Line, Tumor; Cell Survival; Dinoflagellida; Dose-Response Relationship, Drug; Marine Toxins; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2005 |
Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Genes, p53; HT29 Cells; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2006 |
Proanthocyanidin from grape seeds enhances anti-tumor effect of doxorubicin both in vitro and in vivo.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Calcium; Cell Line, Tumor; Doxorubicin; Drug Synergism; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Magnesium; Mice; Neoplasm Transplantation; Proanthocyanidins; Sarcoma 180; Tetrazolium Salts; Thiazoles; Vitis | 2005 |
Evaluation of reduced toxicity of zearalenone by extrusion processing as measured by the MTT cell proliferation assay.
Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; Edible Grain; Enzyme-Linked Immunosorbent Assay; Food Handling; Humans; Tetrazolium Salts; Thiazoles; Zearalenone | 2005 |
Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines.
Topics: Active Transport, Cell Nucleus; Animals; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Genes, Reporter; Immunohistochemistry; Immunoprecipitation; Inflammation; Interleukin-1; Lipopolysaccharides; Luciferases; Models, Biological; Myocardium; NF-kappa B; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Phosphorylation; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Cell Survival; COP9 Signalosome Complex; Curcumin; DNA Fragmentation; Drug Design; Drug Screening Assays, Antitumor; Emodin; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Models, Chemical; Models, Statistical; Multiprotein Complexes; Peptide Hydrolases; Propidium; Proto-Oncogene Proteins c-jun; Signal Transduction; Software; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2005 |
Schisandrin B--a novel inhibitor of P-glycoprotein.
Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line, Tumor; Cell Proliferation; Cyclooctanes; Daunorubicin; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; K562 Cells; Lignans; Models, Chemical; Neoplasms; Polycyclic Compounds; Protein Binding; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway.
Topics: Annexin A5; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; Free Radicals; Guanosine Triphosphate; Humans; Membrane Potentials; Mitochondria; Models, Biological; Neurons; Nitric Oxide; Oxidopamine; Oxygen; Parkinson Disease; Phenols; Polyphenols; Quinones; Reactive Oxygen Species; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2005 |
Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death.
Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antimycin A; Antioxidants; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cell Line, Tumor; Death-Associated Protein Kinases; Electron Transport; Humans; Lysosomes; Membrane Potentials; Microscopy, Electron; Mitochondrial Membranes; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphorylation; Rotenone; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Toxins, Biological | 2005 |
Surface modification of gold and quantum dot nanoparticles with chitosan for bioapplications.
Topics: Animals; Biocompatible Materials; Cadmium; Cell Line, Tumor; Chitosan; Gold; Humans; Light; Mice; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanostructures; NIH 3T3 Cells; Particle Size; Polymers; Quantum Dots; Scattering, Radiation; Selenium; Sulfides; Surface Properties; Tetrazolium Salts; Thiazoles; Trypan Blue; Ultraviolet Rays; Zinc Compounds | 2005 |
The human prothrombin kringle-2 derived peptide, NSA9, is internalized into bovine capillary endothelial cells through endocytosis and energy-dependent pathways.
Topics: Adenosine Triphosphate; Animals; Capillaries; Cattle; Cell Membrane; Cell Proliferation; Chloroquine; Dose-Response Relationship, Drug; Endocytosis; Endothelial Cells; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Kringles; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Nocodazole; Peptides; Protein Structure, Tertiary; Prothrombin; Signal Transduction; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells.
Topics: Animals; Aortic Valve; Biocompatible Materials; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; DNA; Extracellular Matrix; Heart Valves; Microscopy, Confocal; Surface Properties; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2005 |
Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin.
Topics: Animals; beta-Adrenergic Receptor Kinases; Brain; Calcium; Cell Cycle Proteins; Cell Line; Cell Survival; Chlorocebus aethiops; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 2; Gene Library; Genes, Reporter; Green Fluorescent Proteins; Histidine; Humans; Huntingtin Protein; Immunoblotting; Immunoprecipitation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lipids; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Mutation, Missense; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Rats; Receptors, Metabotropic Glutamate; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor TFIIIA; Transfection; Two-Hybrid System Techniques | 2005 |
Domain 5 of high molecular weight kininogen is antibacterial.
Topics: Amino Acid Sequence; Anti-Infective Agents; Antimicrobial Cationic Peptides; Apoptosis; Cell Membrane; Chemotaxis; Diffusion; Enterococcus faecalis; Epitopes; Escherichia coli; Glycosaminoglycans; Gram-Negative Bacteria; Hemolysis; Heparin; Humans; Kinetics; Kininogen, High-Molecular-Weight; Kininogens; L-Lactate Dehydrogenase; Microscopy, Electron; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Neovascularization, Pathologic; Neutrophils; Peptides; Protein Conformation; Protein Structure, Tertiary; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arachidonic Acid; Arachidonic Acids; Blotting, Northern; Blotting, Western; Bone Marrow Cells; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cell Nucleus; Cyclic N-Oxides; Cyclooxygenase 2; Cyclopentanes; F2-Isoprostanes; Genes, Reporter; Hydroxylamine; I-kappa B Proteins; Inflammation; Inhibitory Concentration 50; Isoprostanes; Lipopolysaccharides; Macrophages; Mice; Microscopy, Fluorescence; Models, Chemical; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; PPAR gamma; Prostaglandins; Protein Biosynthesis; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2005 |
Antitumor effect of antisense ODC adenovirus on human prostate cancer cells.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Chromatography, High Pressure Liquid; Collagen; Drug Combinations; Flow Cytometry; G1 Phase; Gene Transfer Techniques; Genetic Therapy; Humans; Laminin; Male; Mice; Mice, Nude; Neoplasm Transplantation; Oligonucleotides, Antisense; Polyamines; Prostatic Neoplasms; Proteoglycans; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Cytotoxicity of MTA and Portland cement on human ECV 304 endothelial cells.
Topics: Aluminum Compounds; Analysis of Variance; Calcium Compounds; Cell Line, Transformed; Cell Survival; Coloring Agents; Dental Cements; Drug Combinations; Endothelial Cells; Humans; Linear Models; Mitochondria; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles | 2005 |
Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells.
Topics: Acetylcysteine; Analysis of Variance; Area Under Curve; Buthionine Sulfoximine; Catalase; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cystine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indolequinones; Iron; Melanins; Models, Biological; Neuroblastoma; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Enhanced efficacy of gemcitabine in combination with anti-CD20 monoclonal antibody against CD20+ non-Hodgkin's lymphoma cell lines in vitro and in scid mice.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Combined Modality Therapy; Deoxycytidine; Gemcitabine; In Vitro Techniques; Inhibitory Concentration 50; Lymphoma, Non-Hodgkin; Mice; Mice, SCID; Neoplasm Transplantation; Poly(ADP-ribose) Polymerases; Rituximab; Tetrazolium Salts; Thiazoles; Translocation, Genetic | 2005 |
Sodium butyrate sensitises human pancreatic cancer cells to both the intrinsic and the extrinsic apoptotic pathways.
Topics: Apoptosis; bcl-X Protein; Blotting, Western; Butyrates; Caspases; Cell Line, Tumor; Cytochromes c; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Mitochondrial Membranes; Pancreatic Neoplasms; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2005 |
In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride.
Topics: Animals; Cadmium Chloride; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Coloring Agents; Humans; L-Lactate Dehydrogenase; Neutral Red; Proteins; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2006 |
Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration.
Topics: Animals; Apoptosis; Astrocytes; Blotting, Western; Calcium; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytokines; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Immunohistochemistry; Inflammation; Interleukin-1; Lipopolysaccharides; Mesencephalon; Microglia; Neuroglia; Neurons; Nitric Oxide; PC12 Cells; Rats; Superoxides; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
The effects of solvents on embryonic stem cell differentiation.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ethanol; Flow Cytometry; Genes, Reporter; Green Fluorescent Proteins; Mice; Mice, Inbred BALB C; Octamer Transcription Factor-3; Reverse Transcriptase Polymerase Chain Reaction; Solvents; Stem Cells; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Platelet-rich plasma influence on human osteoblasts growth.
Topics: Blood Platelets; Cell Division; Cell Proliferation; Cells, Cultured; Coloring Agents; Culture Media; Culture Media, Serum-Free; Humans; Male; Osteoblasts; Plasma; Tetrazolium Salts; Thiazoles | 2005 |
Effects of statins on microglia.
Topics: Amyloid beta-Peptides; Animals; Atorvastatin; Cell Death; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; L-Lactate Dehydrogenase; Lipopolysaccharides; Microglia; Peptide Fragments; Pyrroles; Rats; Simvastatin; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2005 |
Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Abeta in distal axons.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Antidotes; Apoptosis; Axons; Blotting, Western; Calcium-Binding Proteins; Calpain; Cells, Cultured; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Nerve Degeneration; Nerve Growth Factor; Neurons; Peptide Fragments; Prosencephalon; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Tetrazolium Salts; Thiazoles | 2006 |
Modification of MTT assay conditions to examine the cytotoxic effects of amitraz on the human lymphoblastoid cell line, WIL2NS.
Topics: Cell Line; Cell Survival; Coloring Agents; Freezing; Humans; Insecticides; Sodium Dodecyl Sulfate; Tetrazolium Salts; Thiazoles; Toluidines; Toxicity Tests | 2005 |
Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro.
Topics: Antiviral Agents; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Cidofovir; Cyclization; Cytomegalovirus; Cytosine; Enzyme-Linked Immunosorbent Assay; Esters; Fibroblasts; Flow Cytometry; Herpesviridae; Humans; In Situ Hybridization; Organophosphonates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication | 2005 |
Multiparametric assay to screen and dissect the mode of action of anti-human immunodeficiency virus envelope drugs.
Topics: Anti-HIV Agents; Cell Count; Cell Death; Cell Fusion; Cell Line; Cell Survival; Coculture Techniques; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; Tetrazolium Salts; Thiazoles; Viral Envelope Proteins | 2005 |
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Gene Silencing; Humans; Immunoblotting; Laminin; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Plasmids; Prostatic Neoplasms; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Urokinase-Type Plasminogen Activator | 2005 |
Green tea polyphenol epigallocatechin-3-gallate differentially modulates oxidative stress in PC12 cell compartments.
Topics: Animals; Antioxidants; Blotting, Western; Caspase 3; Caspases; Catechin; Cytochrome P-450 CYP2E1; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Induction; Glutathione; Lipid Peroxidation; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2005 |
Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines.
Topics: Acetylcysteine; Annexin A5; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Arthritis, Rheumatoid; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Immunosuppressive Agents; Jurkat Cells; Leukocytes; Methotrexate; Monocytes; Oxidative Stress; Propidium; Reactive Oxygen Species; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors; U937 Cells | 2005 |
Potential irritation of lysine derivative surfactants by hemolysis and HaCaT cell viability.
Topics: Betaine; Cell Line; Cell Survival; Cetrimonium; Cetrimonium Compounds; Colorimetry; Erythrocytes; Hemolysis; Humans; Inhibitory Concentration 50; Irritants; Lysine; Molecular Structure; Neutral Red; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 2006 |
Amyloid-beta causes apoptosis of neuronal cells via caspase cascade, which can be prevented by amyloid-beta-derived short peptides.
Topics: Amyloid beta-Peptides; Analysis of Variance; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Lysosomes; Neuroblastoma; Neurons; Peptide Fragments; Tetrazolium Salts; Thiazoles | 2005 |
Antiviral effect of catechins in green tea on influenza virus.
Topics: Animals; Antiviral Agents; Catechin; Cell Line; Cell Survival; Chickens; Dogs; Enzyme Inhibitors; Erythrocytes; Hemagglutination Inhibition Tests; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Neuraminidase; Reverse Transcriptase Polymerase Chain Reaction; Tea; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication | 2005 |
Metabolism-mediated Ochratoxin A genotoxicity in the single-cell gel electrophoresis (Comet) assay.
Topics: 3T3 Cells; Animals; Biotransformation; Comet Assay; Cytochrome P-450 Enzyme System; Diclofenac; DNA, Complementary; Hydrogen Peroxide; Hydroxylation; Mice; Neutral Red; Ochratoxins; Oxidants; Oxidoreductases; Reactive Oxygen Species; Teratogens; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2006 |
Acrolein-induced cell death in PC12 cells: role of mitochondria-mediated oxidative stress.
Topics: Acrolein; Adenosine Triphosphate; Animals; Apoptosis; Cell Death; Cell Survival; Flow Cytometry; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Necrosis; Oxidative Stress; Oxygen Consumption; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2005 |
In vitro investigation of individual and combined cytotoxic effects of ochratoxin A and other selected mycotoxins on renal cells.
Topics: Algorithms; Animals; Citrinin; Drug Synergism; Indicators and Reagents; Kidney; LLC-PK1 Cells; Models, Biological; Mycotoxins; Ochratoxins; Patulin; Swine; Tetrazolium Salts; Thiazoles | 2006 |
Inhibition of the nuclear factor-kappaB signaling pathway by leflunomide or triptolide also inhibits the anthralin-induced inflammatory response but does not affect keratinocyte growth inhibition.
Topics: Anthralin; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Proliferation; Cells, Cultured; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Humans; I-kappa B Proteins; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Interleukin-8; Isoxazoles; Keratinocytes; Leflunomide; NF-kappa B; Phenanthrenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Antioxidant effects of aqueous extract of Terminalia chebula in vivo and in vitro.
Topics: Animals; Antioxidants; Catechin; Cells, Cultured; Chemical and Drug Induced Liver Injury; Ferric Compounds; Flavonoids; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hepatocytes; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Oxidative Stress; Phenols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Terminalia; Tetrazolium Salts; Thiazoles | 2005 |
Isolation of saponins with the inhibitory effect on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production from Pleurospermum kamtschaticum.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apiaceae; Cell Line; Cell Survival; Dinoprostone; Humans; Lipopolysaccharides; Macrophages; Nitric Oxide; Plant Extracts; Prostaglandin Antagonists; Sapogenins; Saponins; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
Gymnasterkoreayne G, a new inhibitory polyacetylene against NFAT transcription factor from Gymnaster koraiensis.
Topics: Acetylene; Alkynes; Asteraceae; Buffers; DNA-Binding Proteins; Humans; Indicators and Reagents; Jurkat Cells; Magnetic Resonance Spectroscopy; NFATC Transcription Factors; Nuclear Proteins; Plant Extracts; Simian Immunodeficiency Virus; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Transcription Factors | 2005 |
The inhibitory effect and possible mechanisms of D-allose on cancer cell proliferation.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA; Fructose; Gene Expression Regulation, Neoplastic; Glucose; HeLa Cells; Hexoses; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Models, Chemical; Monosaccharides; Neoplasms; Reactive Oxygen Species; Sugar Alcohols; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Bovine seminal ribonuclease is cytotoxic for both malignant and normal telomerase-positive cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cattle; Cell Differentiation; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Down-Regulation; Endoribonucleases; Enzyme-Linked Immunosorbent Assay; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Lymphocytes; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; T-Lymphocytes; Telomerase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2005 |
[MTT in the evaluation of culture cells of newborn calf sera].
Topics: Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Line; Cell Survival; Serum; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2004 |
Reduction of MTT by flavonoids in the absence of cells.
Topics: Cell Survival; Dimethyl Sulfoxide; False Negative Reactions; Luteolin; Oxidation-Reduction; Quercetin; Tetrazolium Salts; Thiazoles | 2005 |
Novel biomimetic polymersomes as polymer therapeutics for drug delivery.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Biomimetics; Cell Adhesion; Cell Shape; Cell Survival; Cells, Cultured; Doxorubicin; Drug Delivery Systems; Emulsions; Materials Testing; Methacrylates; Mice; Micelles; Microscopy, Electron, Transmission; Nanostructures; Osteoblasts; Phosphorylcholine; Polymers; Spectrometry, Fluorescence; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 2005 |
L-arginine stimulates immune response in chickens immunized with intermediate plus strain of infectious bursal disease vaccine.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Antibody Formation; Arginine; Birnaviridae Infections; Cell Proliferation; Chick Embryo; Chickens; Electrophoresis, Agar Gel; Enzyme-Linked Immunosorbent Assay; Hemagglutination Inhibition Tests; Immunity, Cellular; Infectious bursal disease virus; Lethal Dose 50; Organ Size; Poultry Diseases; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2006 |
Not all 2 Gray radiation prescriptions are equivalent: Cytotoxic effect depends on delivery sequences of partial fractionated doses.
Topics: Animals; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; Radiation Tolerance; Relative Biological Effectiveness; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2005 |
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
Topics: Adenosine Triphosphate; Albendazole; Amitriptyline; Animals; Buthionine Sulfoximine; Carbamazepine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromans; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flutamide; Glutathione; Humans; Isoniazid; Microsomes; Ochratoxins; Piperazines; Quinidine; Substrate Specificity; Tamoxifen; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Toxicity Tests; Triazolam; Troglitazone; Xenobiotics | 2005 |
Uptake and transport of PEG-graft-trimethyl-chitosan copolymer-insulin nanocomplexes by epithelial cells.
Topics: Algorithms; Animals; Biological Transport; Caco-2 Cells; Chemical Phenomena; Chemistry, Physical; Chitosan; Epithelial Cells; Humans; Hypoglycemic Agents; Insulin; Light; Male; Microscopy, Confocal; Molecular Weight; Nanostructures; Particle Size; Polyethylene Glycols; Predictive Value of Tests; Rats; Scattering, Radiation; Tetrazolium Salts; Thiazoles; Tight Junctions | 2005 |
Brain-derived neurotrophic factor is neuroprotective against human immunodeficiency virus-1 envelope proteins.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Death; Cerebellum; HIV Envelope Protein gp120; Humans; In Situ Nick-End Labeling; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Receptors, Chemokine; Tetrazolium Salts; Thiazoles | 2005 |
In vitro effects of staphylococcal leukocidin LukE/LukD on the proliferative ability of lymphocytes isolated from common carp (Cyprinus carpio L.).
Topics: Animals; Bacterial Proteins; Carps; Cell Proliferation; Concanavalin A; Dose-Response Relationship, Drug; Exotoxins; Lipopolysaccharides; Lymphocytes; Tetrazolium Salts; Thiazoles | 2006 |
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53.
Topics: Adult; Aged; Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Nucleus; Cisplatin; Cloning, Molecular; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Genes, p53; Head and Neck Neoplasms; Humans; Immunohistochemistry; Microscopy, Confocal; Middle Aged; Models, Molecular; Mutation; Nuclear Localization Signals; Open Reading Frames; Protein Structure, Tertiary; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2005 |
Curcumin suppresses growth of head and neck squamous cell carcinoma.
Topics: Animals; Annexin A5; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Nucleus; Cell Separation; Cell Survival; Curcumin; Cyclin D1; Dose-Response Relationship, Drug; Female; Flow Cytometry; Head and Neck Neoplasms; Humans; I-kappa B Proteins; In Vitro Techniques; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Tetrazolium Salts; Thiazoles | 2005 |
Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.
Topics: Acetyltransferases; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Hydrogen Peroxide; Oxidoreductases Acting on CH-NH Group Donors; Peroxisomes; Polyamine Oxidase; Polyamines; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Thermoresponsive polymers as gene delivery vectors: cell viability, DNA transport and transfection studies.
Topics: Acrylic Resins; Animals; Cell Line; Cell Survival; Chemical Phenomena; Chemistry, Physical; DNA; Gene Transfer Techniques; Green Fluorescent Proteins; Mice; Mice, Inbred C3H; Microscopy, Confocal; Muscle, Skeletal; Polymers; Temperature; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
The chemical constitution and biocompatibility of accelerated Portland cement for endodontic use.
Topics: Aluminum Compounds; Biocompatible Materials; Bismuth; Calcium Compounds; Calcium Hydroxide; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Dental Cements; Drug Combinations; Electron Probe Microanalysis; Humans; Indicators and Reagents; Materials Testing; Osteosarcoma; Oxazines; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; X-Ray Diffraction; Xanthenes | 2005 |
Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia.
Topics: Animals; Brain Infarction; Brain Ischemia; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Glutamic Acid; Guanidines; Mice; N-Methylaspartate; Neurons; Reperfusion; Sodium-Hydrogen Exchangers; Tetrazolium Salts; Thiazoles | 2005 |
N-Arylpiperazine modified analogues of the P2X7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid Phosphatase; Apoptosis; Bone and Bones; Bone Diseases, Metabolic; Caspase 3; Caspases; Cell Nucleus; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Isoenzymes; Models, Chemical; NF-kappa B; Osteoblasts; Osteoclasts; Piperazines; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7; Tartrate-Resistant Acid Phosphatase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Chrysoeriol potently inhibits the induction of nitric oxide synthase by blocking AP-1 activation.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Digitalis; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavones; Flavonoids; Immunoblotting; Lipopolysaccharides; Macrophages; Male; Mice; Models, Chemical; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligonucleotides; Plant Leaves; Promoter Regions, Genetic; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2005 |
BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 8; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Cytochromes c; fas Receptor; Gene Transfer Techniques; Genes, p53; Genetic Therapy; Humans; Inhibitory Concentration 50; Liposomes; Models, Statistical; Necrosis; Oligonucleotides, Antisense; Phosphatidylethanolamines; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Transfection; Transferrin; Tumor Suppressor Protein p53 | 2005 |
Epidermal morphogenesis in an in-vitro model using a fibroblasts-embedded collagen scaffold.
Topics: Animals; Cell Communication; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Culture Media; Dermis; DNA Primers; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Epidermis; Extracellular Matrix; Fibroblast Growth Factor 7; Fibroblasts; Immunohistochemistry; Keratinocytes; Microscopy, Electron, Scanning; Models, Biological; Organ Culture Techniques; Phenotype; Polymers; Reverse Transcriptase Polymerase Chain Reaction; Skin; Swine; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
A comparison of colorimetric and DNA quantification assays for the assessment of meniscal fibrochondrocyte proliferation in microcarrier culture.
Topics: Animals; Biological Assay; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chondrocytes; Colorimetry; DNA; Fibrocartilage; Mitochondria; Sensitivity and Specificity; Sheep; Tetrazolium Salts; Thiazoles | 2005 |
Responses of microglia in vitro to the gram-positive bacterial component, lipoteichoic acid.
Topics: Animals; Animals, Newborn; Annexin A5; Antibodies; Apoptosis; Blotting, Western; Brain; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Antibody Technique; Gene Expression Regulation; Gram-Positive Bacteria; Histocompatibility Antigens Class II; Ki-67 Antigen; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage-1 Antigen; Microglia; Microscopy, Electron, Scanning; Nitric Oxide Synthase Type II; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; RNA-Binding Proteins; Teichoic Acids; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Vascular targeting in pancreatic cancer: the novel tubulin-binding agent ZD6126 reveals antitumor activity in primary and metastatic tumor models.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Coloring Agents; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Immunohistochemistry; Liver; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Chemical; Necrosis; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphorus Compounds; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Tubulin; Umbilical Veins | 2005 |
Effect of ecdysterone on glucose metabolism in vitro.
Topics: Animals; Cell Line, Tumor; Chromans; Dose-Response Relationship, Drug; Ecdysterone; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Liver Neoplasms; Metformin; Mice; Mice, Transgenic; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2006 |
Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Biotransformation; Caspases; Cell Line; Cell Separation; Cytochromes c; Dogs; Genes, bcl-2; Hydrogen Peroxide; Hypoxia; In Situ Nick-End Labeling; Inflammation; Isoflurane; L-Lactate Dehydrogenase; Male; Myocytes, Cardiac; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2005 |
Effect of latanoprost on cultured porcine corneal stromal cells.
Topics: Animals; Benzalkonium Compounds; Calcium; Cell Movement; Cells, Cultured; Collagen Type I; Corneal Stroma; Fibronectins; Fluorescent Antibody Technique; Immunoblotting; Intracellular Membranes; Latanoprost; Leucine; Proline; Prostaglandins F, Synthetic; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles; Thymidine; Uridine | 2005 |
Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Blotting, Western; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neurotoxicity Syndromes; Peptide Fragments; Tetrazolium Salts; Thiazoles | 2006 |
Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene glycol): in vitro and in vivo studies.
Topics: Animals; Asialoglycoprotein Receptor; Cell Line, Tumor; Cell Survival; DNA; Drug Delivery Systems; Electrochemistry; Gene Expression Regulation; Genes, ras; Genetic Therapy; Green Fluorescent Proteins; Hepatocytes; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Polyethylene Glycols; Radionuclide Imaging; Technetium; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
Cytotoxicity and cytoprotective activity in naphthalenediols depends on their tendency to form naphthoquinones.
Topics: Animals; Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Free Radicals; Hot Temperature; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Models, Chemical; Naphthols; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Quinones; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Cadmium chloride-induced oxidative stress in skeletal muscle cells in vitro.
Topics: Animals; Antioxidants; Cadmium Chloride; Cell Adhesion; Cell Death; Cell Differentiation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Glutathione Transferase; In Vitro Techniques; Lipid Peroxidation; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Oxidative Stress; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Wnt/beta-catenin signaling mediates antineoplastic effects of imatinib mesylate (gleevec) in anaplastic thyroid cancer.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; beta Catenin; Blotting, Western; Carcinoma; Caspase 3; Caspase 7; Caspases; Cell Proliferation; Collagen; Drug Combinations; Fluorescent Antibody Technique; Genes, Reporter; Humans; Imatinib Mesylate; Immunoprecipitation; Laminin; Luciferases; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Piperazines; Proteoglycans; Pyrimidines; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Thyroid Neoplasms; Transfection; Tumor Cells, Cultured | 2006 |
Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.
Topics: Alanine; Alzheimer Disease; Animals; Benzothiazoles; Cell Survival; Circular Dichroism; Disulfides; Endostatins; Escherichia coli; Fibril-Associated Collagens; Fluorescent Dyes; Glutathione; Hydrogen-Ion Concentration; Light; Microscopy, Atomic Force; Neovascularization, Pathologic; PC12 Cells; Protein Conformation; Protein Structure, Tertiary; Rats; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
Neural precursor cell susceptibility to human cytomegalovirus diverges along glial or neuronal differentiation pathways.
Topics: AC133 Antigen; Antigens, CD; beta-Galactosidase; Blotting, Western; Brain; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Cytomegalovirus; Fetus; Flow Cytometry; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycoproteins; Growth Substances; Humans; Immunohistochemistry; Intermediate Filament Proteins; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Peptides; Platelet-Derived Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Targeted therapy against Bcl-2-related proteins in breast cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Genes, bcl-2; Humans; Mice; Mice, Nude; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 2005 |
G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase.
Topics: Amino Acid Chloromethyl Ketones; Animals; Blotting, Western; Bromodeoxyuridine; Calcium; Caspases; Cell Proliferation; CHO Cells; Chromatin; Coloring Agents; Cricetinae; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Genetic Vectors; Humans; Indoles; Maleimides; MAP Kinase Signaling System; Orexin Receptors; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2006 |
Neuroprotective properties of afobazol in vitro.
Topics: Animals; Benzimidazoles; Cell Line; Cell Survival; Glutamic Acid; Hydrogen Peroxide; In Vitro Techniques; Mice; Morpholines; Neurons; Neuroprotective Agents; Oxidative Stress; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Cytotoxicity of a new toothpaste based on an ion exchange resin mixture.
Topics: Animals; Calcium; Cell Survival; Colorimetry; Coloring Agents; Fibroblasts; Fluorides; Ion Exchange Resins; L Cells; Mice; Phosphates; Tetrazolium Salts; Thiazoles; Tooth Remineralization; Toothpastes; Zinc | 2005 |
Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells.
Topics: Animals; Cations; Cell Line; Cell Survival; DNA; Drug Stability; Drug Storage; Freeze Drying; Genes, Reporter; Genetic Therapy; Luciferases; Mice; Mitosis; Polylysine; Polymers; Retina; Tetrazolium Salts; Thiazoles; Transducin; Transfection | 2006 |
Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells.
Topics: 5' Untranslated Regions; Amantadine; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dopamine Agents; Glial Cell Line-Derived Neurotrophic Factor; Glioma; Immunoassay; Memantine; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2006 |
G-CSF protects human cerebral hybrid neurons against in vitro ischemia.
Topics: Blotting, Western; Brain Ischemia; Cell Death; Cell Line; Cell Survival; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Hybrid Cells; L-Lactate Dehydrogenase; Necrosis; Neurons; Neuroprotective Agents; Tetrazolium Salts; Thiazoles; Transcription, Genetic | 2006 |
Optimization and validation of a colorimetric assay for Tetrahymena sp. survival.
Topics: Animals; Cell Survival; Cells, Cultured; Chloramines; Colorimetry; Copper Sulfate; Drug Evaluation, Preclinical; Environmental Pollutants; Formaldehyde; Hydrogen Peroxide; Rosaniline Dyes; Sodium Chloride; Tetrahymena; Tetrazolium Salts; Thiazoles; Tosyl Compounds | 2006 |
Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation.
Topics: Apoptosis; Arrestins; beta-Arrestins; Binding Sites; Casein Kinase II; Cell Death; Cell Line, Tumor; Cell Nucleus; Cell Separation; DNA Fragmentation; Dose-Response Relationship, Radiation; Epidermis; Flow Cytometry; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Models, Biological; Models, Statistical; NF-kappa B; Phosphorylation; Plasmids; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Ultraviolet Rays | 2005 |
Strong electronic charge as an important factor for anticancer activity of chitooligosaccharides (COS).
Topics: Acridine Orange; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; DNA Fragmentation; Electrochemistry; Electrophoresis, Agar Gel; Ethidium; Fibroblasts; Fluorescent Dyes; Humans; Indicators and Reagents; Microscopy, Fluorescence; Necrosis; Neutral Red; Oligosaccharides; Tetrazolium Salts; Thiazoles | 2006 |
Trans-arachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration.
Topics: Animals; Apoptosis; Arachidonic Acids; Blotting, Western; Cell Survival; Cells, Cultured; Diabetic Angiopathies; DNA Primers; Endothelial Cells; Gene Expression Regulation; In Situ Nick-End Labeling; Neovascularization, Physiologic; Nitric Oxide; Rats; Rats, Sprague-Dawley; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Sus scrofa; Tetrazolium Salts; Thiazoles; Thrombospondin 1 | 2005 |
Astrocyte reactivity to Fas activation is attenuated in TIMP-1 deficient mice, an in vitro study.
Topics: Animals; Animals, Newborn; Antibodies; Astrocytes; Blotting, Western; Brain; Cell Count; Cell Death; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; fas Receptor; Flow Cytometry; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lymphocytes; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Receptors, Tumor Necrosis Factor; Tetrazolium Salts; Thiazoles; Thymidine; Tissue Inhibitor of Metalloproteinase-1; Tritium; Tumor Necrosis Factor-alpha | 2005 |
Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics.
Topics: Cell Line, Tumor; Deoxyribonucleases; Drug Delivery Systems; Epidermal Growth Factor; ErbB Receptors; Gene Transfer Techniques; Genetic Vectors; Humans; Infusions, Intravenous; Iodides; K562 Cells; Kinetics; Ligands; Neoplasm Transplantation; Oncogene Proteins v-erbB; Peptide Library; Peptides; Polyethyleneimine; Protein Binding; Tetrazolium Salts; Thiazoles; Transfection | 2005 |
The permeability and cytotoxicity of insulin-mimetic vanadium (III,IV,V)-dipicolinate complexes.
Topics: Caco-2 Cells; Chelating Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Electric Impedance; Epithelial Cells; Humans; Insulin; Intestinal Mucosa; Intestines; Organometallic Compounds; Oxidation-Reduction; Permeability; Picolinic Acids; Tetrazolium Salts; Thiazoles; Tight Junctions; Time Factors; Vanadium Compounds | 2006 |
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells.
Topics: Antidepressive Agents; Blotting, Western; Cell Line; Cell Survival; Cholesterol; Fatty Acids; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Synthase; Neuroglia; Reverse Transcriptase Polymerase Chain Reaction; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Proteins; Tetrazolium Salts; Thiazoles; Up-Regulation | 2006 |
Neuronal cell death induced by cystatin C in vivo and in cultured human CNS neurons is inhibited with cathepsin B.
Topics: Animals; Apoptosis; Astrocytes; Caspase 3; Caspases; Cathepsin B; Cell Death; Cell Survival; Cells, Cultured; Central Nervous System; Cystatin C; Cystatins; DNA; Hippocampus; Humans; Hybrid Cells; Immunohistochemistry; In Situ Nick-End Labeling; Male; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2005 |
Cartap-induced cytotoxicity in mouse C2C12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects.
Topics: Animals; Antioxidants; Calcium; Cell Line; Cell Survival; Creatine Kinase; Drug Screening Assays, Antitumor; Insecticides; Isoenzymes; L-Lactate Dehydrogenase; Mice; Myoblasts; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thiocarbamates; Trypan Blue | 2006 |
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitochondria; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane; Tetrazolium Salts; Thiazoles | 2005 |
Three new podocarpane-type diterpenoids from callus of Securinega suffruticosa.
Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Diterpenes; Drug Screening Assays, Antitumor; Euphorbiaceae; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2005 |
In vitro effects of fluoroquinolone and aminoglycoside antibiotics on human keratocytes.
Topics: Adult; Annexin A5; Anti-Bacterial Agents; Cell Proliferation; Cells, Cultured; Corneal Stroma; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Humans; Male; Microscopy, Phase-Contrast; Middle Aged; Netilmicin; Ofloxacin; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Studies on the epitope of neuronal growth inhibitory factor (GIF) with using of the specific antibody.
Topics: Amino Acid Sequence; Animals; Central Nervous System; Enzyme-Linked Immunosorbent Assay; Epitopes; Hippocampus; Humans; Metallothionein 3; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peptides; Protein Structure, Tertiary; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2005 |
A novel simplified ultra-rapid freezing technique for cryopreservation of tissue slices.
Topics: Animals; Cell Survival; Cryopreservation; Freezing; L-Lactate Dehydrogenase; Liver; Male; Mice; Organ Preservation; Tetrazolium Salts; Thiazoles; Time Factors; Umbelliferones | 2006 |
17beta-estradiol (betaE2) protects human retinal Müller cell against oxidative stress in vitro: evaluation of its effects on gene expression by cDNA microarray.
Topics: Antioxidants; Apoptosis; Cells, Cultured; Estradiol; Flow Cytometry; Gene Expression; Humans; Hydrogen Peroxide; Oligonucleotide Array Sequence Analysis; Oxidants; Oxidative Stress; Pigment Epithelium of Eye; Retina; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2006 |
Adiponectin induces growth arrest and apoptosis of MDA-MB-231 breast cancer cell.
Topics: Adiponectin; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Plasmids; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2005 |
Bright fluorescent nanodiamonds: no photobleaching and low cytotoxicity.
Topics: Cell Line; Diamond; Fluorescent Dyes; Humans; Kidney; Microscopy, Confocal; Nanostructures; Photobleaching; Quantum Theory; Tetrazolium Salts; Thiazoles | 2005 |
1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Count; Cell Line, Tumor; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Motor Activity; Neuroblastoma; Neurotoxicity Syndromes; Parkinson Disease; Rats; Rotarod Performance Test; Substantia Nigra; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Transgenes; Tyrosine 3-Monooxygenase | 2006 |
The effect of laser therapy on the proliferation of oral KB carcinoma cells: an in vitro study.
Topics: Cell Proliferation; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Humans; KB Cells; Lasers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
Expression of dihydrodiol dehydrogenase plays important roles in apoptosis- and drug-resistance of A431 squamous cell carcinoma.
Topics: Apoptosis; Bleomycin; Carcinoma, Squamous Cell; Caspase 3; Caspases; Cell Line; Cell Line, Tumor; Disease Progression; Drug Resistance, Neoplasm; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Keratinocytes; Models, Statistical; Oxidoreductases; Polycyclic Aromatic Hydrocarbons; Prognosis; RNA Interference; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Ultraviolet Rays; Up-Regulation | 2006 |
Hypoglycemia influences oligodendrocyte development and myelin formation.
Topics: Animals; Animals, Newborn; Blotting, Western; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Movement; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Glucose; Hypoglycemia; Immunohistochemistry; In Situ Nick-End Labeling; In Vitro Techniques; Mice; Myelin Basic Protein; Myelin Sheath; Oligodendroglia; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
A clinoptilolite effect on cell media and the consequent effects on tumor cells in vitro.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Chromatography, Ion Exchange; Culture Media; DNA; ErbB Receptors; Humans; Immunoprecipitation; In Vitro Techniques; Ions; MAP Kinase Kinase 4; Mice; Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-akt; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Zeolites | 2006 |
Novel biodegradable films and scaffolds of chitosan blended with poly(3-hydroxybutyrate).
Topics: Absorbable Implants; Animals; Biocompatible Materials; Biodegradation, Environmental; Biomedical Engineering; Bone Substitutes; Cell Culture Techniques; Chitin; Chitosan; Culture Media; Culture Techniques; Durapatite; Emulsions; Fibroblasts; Hydroxybutyrates; Manufactured Materials; Materials Testing; Mice; Microscopy, Electron, Scanning; NIH 3T3 Cells; Polyesters; Polymers; Porosity; Stress, Mechanical; Surface Properties; Temperature; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2005 |
Properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) films modified with polyvinylpyrrolidone and behavior of MC3T3-E1 osteoblasts cultured on the blended films.
Topics: 3-Hydroxybutyric Acid; 3T3 Cells; Adsorption; Animals; Biocompatible Materials; Caproates; Cell Adhesion; Cell Proliferation; Cells, Cultured; Coloring Agents; Extracellular Matrix; Fibronectins; Hydroxybutyrates; Laminin; Materials Testing; Mice; Microscopy, Electron, Scanning; Models, Chemical; Molecular Conformation; Osteoblasts; Polyesters; Polymers; Povidone; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2005 |
Pro- and anti-inflammatory cytokines regulate the ERK pathway: implication of the timing for the activation of microglial cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Cerebral Cortex; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethidium; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hippocampus; Interleukin-1; Neuroglia; Neurons; Nitrites; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Neuroprotective effects of nicotine against salsolinol-induced cytotoxicity: implications for Parkinson's disease.
Topics: Cell Death; Cell Line, Tumor; Cell Survival; Conotoxins; Dose-Response Relationship, Drug; Drug Interactions; Humans; Isoquinolines; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Nicotine; Tetrazolium Salts; Thiazoles | 2005 |
The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells.
Topics: 2',5'-Oligoadenylate Synthetase; 3T3 Cells; Amino Acid Sequence; Animals; Antiviral Agents; Base Sequence; Blotting, Southern; Blotting, Western; Cell Line; Cell Survival; Culicidae; DNA Primers; Endoribonucleases; Fibroblasts; Fluorescent Antibody Technique, Indirect; Immunity; Immunoprecipitation; Interferons; Mice; Molecular Sequence Data; Protease Inhibitors; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Transfection; Virus Replication; West Nile Fever; West Nile virus | 2006 |
GDNF family ligands display distinct action profiles on cultured GABAergic and serotonergic neurons of rat ventral mesencephalon.
Topics: Analysis of Variance; Animals; Cell Count; Cells, Cultured; Embryo, Mammalian; gamma-Aminobutyric Acid; Glial Cell Line-Derived Neurotrophic Factors; Immunohistochemistry; Mesencephalon; Neurites; Neurons; Phosphopyruvate Hydratase; Rats; Serotonin; Tetrazolium Salts; Thiazoles | 2006 |
Varying the unsaturation in N4,N9-dioctadecanoyl spermines: nonviral lipopolyamine vectors for more efficient plasmid DNA formulation.
Topics: Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; DNA; Drug Carriers; Electrochemistry; Fatty Acids; Glycine; Humans; Indicators and Reagents; Nanostructures; Particle Size; Plasmids; Skin; Spermine; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Ethanol-induced CXC-chemokine synthesis and barrier dysfunction in intestinal epithelial cells.
Topics: Alcoholic Intoxication; Algorithms; Animals; Bacterial Translocation; Cell Line; Cell Membrane Permeability; Cell Survival; Central Nervous System Depressants; Chemokines, CXC; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Ethanol; Interleukin-1; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Neutrophils; Rats; Tetrazolium Salts; Thiazoles | 2005 |
Rho/ROCK pathway as a target of tumor therapy.
Topics: Amides; Animals; Antineoplastic Agents; Apoptosis; Blotting, Southern; Blotting, Western; Caspases; Cell Survival; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Lovastatin; Male; Mevalonic Acid; Mice; Neoplasms; Neoplasms, Experimental; Polyisoprenyl Phosphates; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2006 |
Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity.
Topics: Acetylcysteine; Amides; Amyloid beta-Peptides; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Neurons; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action.
Topics: Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Flavonoids; Humans; Models, Chemical; Mutation; Neoplasms; Plant Extracts; Tetrazolium Salts; Thiazoles | 2006 |
Effects of poly-L-arginine on the permeation of hydrophilic compounds through surface ocular tissues.
Topics: Animals; Buffers; Conjunctiva; Cornea; Dextrans; Electric Conductivity; Electrophysiology; Eye; Fluorescein-5-isothiocyanate; In Vitro Techniques; Male; Molecular Weight; Peptides; Permeability; Polylysine; Pyridoxamine; Rabbits; Sclera; Tetrazolium Salts; Thiazoles | 2006 |
New stilbenoids from Pholidota yunnanensis and their inhibitory effects on nitric oxide production.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Liquid; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Orchidaceae; Phenanthrenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stilbenes; Tetrazolium Salts; Thiazoles | 2006 |
Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-alpha, IL-1beta and IL-2.
Topics: Acetates; Animals; Blotting, Western; Cell Proliferation; Commiphora; Down-Regulation; Genes, fos; Genes, jun; Humans; Indicators and Reagents; Interleukin-1; Interleukin-2; Lymphocyte Culture Test, Mixed; Macrophages; Mice; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase Type II; Phytohemagglutinins; Plant Extracts; RNA, Messenger; Solvents; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
Inhibition of N-methyl-D-aspartate receptor function appears to be one of the common actions for antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Calcium; Calcium Signaling; Cell Survival; Desipramine; Excitatory Amino Acid Antagonists; Fluoxetine; Hippocampus; L-Lactate Dehydrogenase; Moclobemide; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type I; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Modulation of the transforming growth factor-beta signal transduction pathway by hepatitis C virus nonstructural 5A protein.
Topics: Amino Acids; Animals; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cytokines; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Fibrosis; Genes, Reporter; Glutathione Transferase; Humans; Immunoprecipitation; Liver; Luciferases; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Plasmids; Protein Binding; Regeneration; Risk Factors; Signal Transduction; Smad3 Protein; Smad4 Protein; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor beta; Viral Nonstructural Proteins | 2006 |
c-Myc inhibition negatively impacts lymphoma growth.
Topics: Animals; Burkitt Lymphoma; Down-Regulation; Fibroblasts; Gene Expression Profiling; Herpesvirus 4, Human; Oligonucleotide Array Sequence Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2006 |
Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria.
Topics: Aconitate Hydratase; Animals; Brain; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex I; Electrons; Fatty Acids; Glutathione; Hydrogen Peroxide; Mitochondria; NADP; Oxidative Phosphorylation; Oxidative Stress; Oxygen; Palmitic Acid; Phytanic Acid; Rats; Rotenone; Tetrazolium Salts; Thiazoles; Time Factors; Uncoupling Agents | 2006 |
Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase.
Topics: Aged; Aged, 80 and over; Astrocytes; Case-Control Studies; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Glial Fibrillary Acidic Protein; Glutathione Peroxidase; Humans; Immunohistochemistry; Male; Nerve Growth Factors; Neurons; Parkinson Disease; Prothrombin; Receptor, PAR-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors; Up-Regulation | 2006 |
Depolarization and Ca(2+) down regulate CB1 receptors and CB1-mediated signaling in cerebellar granule neurons.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Blotting, Northern; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebellum; Cyclohexanols; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; In Situ Hybridization; Models, Biological; Neurons; Nifedipine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Signal Transduction; Tetrazolium Salts; Tetrodotoxin; Thiazoles; Time Factors | 2006 |
Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Benzimidazoles; Calmodulin-Binding Proteins; Catechin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Flavonoids; Fluoroimmunoassay; Hippocampus; Neurons; Neuroprotective Agents; Peptide Fragments; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
Oregano (Lippia spp.) kills Giardia intestinalis trophozoites in vitro: antigiardiasic activity and ultrastructural damage.
Topics: Animals; Antiprotozoal Agents; Cell Nucleus; Cell Survival; Giardia lamblia; Humans; Microscopy, Electron, Transmission; Origanum; Plant Extracts; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trophozoites | 2006 |
Apoptosis of HL-60 cells induced by extracts from Narcissus tazetta var. chinensis.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Narcissus; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2006 |
Mechanisms of 5-aminolevulinic acid ester uptake in mammalian cells.
Topics: Aminolevulinic Acid; Animals; Biological Transport, Active; Cell Line; Cell Line, Tumor; Cell Membrane; Cytoplasm; Diffusion; Female; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Porphyrins; Succinic Acid; Temperature; Tetrazolium Salts; Thiazoles | 2006 |
Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line.
Topics: Antimitotic Agents; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Primers; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Histones; Humans; Isoflavones; Kinesins; Male; Models, Statistical; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Spindle Apparatus; Tetrazolium Salts; Thiazoles | 2006 |
Parameters for cellular viability and membrane function in chenopodium cells show a specific response of extracellular pH to heat shock with extreme Q10.
Topics: 2,6-Dichloroindophenol; Alkaline Phosphatase; Animals; Betalains; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chenopodium; Extracellular Fluid; Heat-Shock Response; Humans; Hydrogen-Ion Concentration; Nigericin; Plant Proteins; Temperature; Tetrazolium Salts; Thiazoles | 2006 |
Expression of myelin basic protein in two oligodendroglial cell lines is modulated by apotransferrin through different transcription factors.
Topics: Apoproteins; Blotting, Western; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Complementary; Electrophoretic Mobility Shift Assay; Genes, Reporter; Lac Operon; Myelin Basic Protein; NF-kappa B; Nuclear Proteins; Oligodendroglia; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sp1 Transcription Factor; Tetrazolium Salts; Thiazoles; Thyroid Hormones; Transcription Factors; Transferrin; Tumor Necrosis Factor-alpha | 2006 |
Fetal intestinal fibroblasts respond to insulin-like growth factor (IGF)-II better than adult intestinal fibroblasts.
Topics: Age Factors; Animals; Blotting, Western; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Female; Fibroblasts; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Jejunum; Pregnancy; Radioimmunoassay; Sheep; Tetrazolium Salts; Thiazoles | 2006 |
An isotonic preparation of 1 mg/ml indocyanine green is not toxic to hyperconfluent ARPE19 cells, even after prolonged exposure.
Topics: Cell Line; Cell Survival; Coloring Agents; Humans; Indocyanine Green; Isotonic Solutions; Pigment Epithelium of Eye; Retinal Perforations; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Comparison of redox and D29 phage methods for detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Costs and Cost Analysis; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Mycobacteriophages; Mycobacterium tuberculosis; Oxazines; Oxidation-Reduction; Rifampin; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Xanthenes | 2006 |
Induction of neuronal differentiation of adult human olfactory neuroepithelial-derived progenitors.
Topics: Adult; Aged, 80 and over; Analysis of Variance; Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; Coculture Techniques; Colforsin; Drug Interactions; Female; Gene Expression Regulation, Developmental; Hedgehog Proteins; Humans; Indoles; Male; Muscle Cells; Neurites; Neurons; Olfactory Mucosa; Phosphopyruvate Hydratase; Stem Cells; Synapsins; Tetrazolium Salts; Thiazoles; Trans-Activators; Transcription Factors; Tretinoin; Tyrosine 3-Monooxygenase; Vesicular Acetylcholine Transport Proteins | 2006 |
Growth inhibitory effect of quercetin on SW 872 human liposarcoma cells.
Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Liposarcoma; Membrane Potentials; Mitochondria; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Quercetin; Tetrazolium Salts; Thiazoles | 2006 |
A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluorouracil; Gemcitabine; Humans; Pancreatic Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Ribonucleotide Reductases; Sulfonamides; Tetrazolium Salts; Thiazoles | 2006 |
Chunghyuldan activates NOS mRNA expression and suppresses VCAM-1 mRNA expression in human endothelial cells.
Topics: DNA, Complementary; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Induction; Enzyme Inhibitors; Flow Cytometry; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thymidine; Triazenes; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2005 |
A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death.
Topics: Adenosine; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Astrocytoma; Caspases; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Immunohistochemistry; Mitochondrial Membranes; Models, Biological; Multienzyme Complexes; Protein Serine-Threonine Kinases; Rats; Receptor, Adenosine A1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Theophylline; Thiazoles | 2006 |
Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons.
Topics: Adrenergic Agents; Aminoglutethimide; Animals; Brain Ischemia; Calcium; Cell Death; Cerebral Cortex; Female; Glutamic Acid; L-Lactate Dehydrogenase; Neurons; Neurotoxins; Organ Culture Techniques; Rats; Steroids; Tetrazolium Salts; Thiazoles | 2006 |
New antitumour active platinum compounds containing carboxylate ligands in trans geometry: synthesis, crystal structure and biological activity.
Topics: Animals; Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Neoplasms; Platinum Compounds; Tetrazolium Salts; Thiazoles | 2006 |
Kinetic analysis on the skin disposition of cytotoxicity as an index of skin irritation produced by cetylpyridinium chloride: comparison of in vitro data using a three-dimensional cultured human skin model with in vivo results in hairless mice.
Topics: Algorithms; Animals; Cell Survival; Cells, Cultured; Cetylpyridinium; Chromatography, High Pressure Liquid; Dermis; Detergents; Epidermal Cells; Epidermis; Humans; Irritants; Kinetics; Male; Mice; Mice, Hairless; Skin; Spectrophotometry, Ultraviolet; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2006 |
Induction of apoptosis in leukemia cell lines by Linum persicum and Euphorbia cheiradenia.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorimetry; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Euphorbia; Flax; Flow Cytometry; HeLa Cells; Humans; Jurkat Cells; K562 Cells; Leukemia; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles | 2006 |
A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Carbazoles; Caspase 3; Caspases; Cell Count; Cells, Cultured; Cerebellum; Colchicine; Cytoskeleton; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Immunohistochemistry; Indoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred BALB C; Neurons; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.
Topics: Arsenates; Arsenic; Arsenites; Biological Transport, Active; Cacodylic Acid; Cell Line; DNA Primers; DNA, Complementary; Estradiol; Humans; Immunoblotting; Lethal Dose 50; Liver-Specific Organic Anion Transporter 1; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; Taurocholic Acid; Tetrazolium Salts; Thiazoles; Toxicity Tests; Transfection | 2006 |
Effect of the Fusarium toxin deoxynivalenol (DON) on IgA, IgM and IgG concentrations and proliferation of porcine blood lymphocytes.
Topics: Animals; Bromodeoxyuridine; Cycloheximide; Dose-Response Relationship, Drug; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Lymphocyte Activation; Swine; Tetrazolium Salts; Thiazoles; Trichothecenes | 2006 |
Effect of cobalt and chromium ions on human MG-63 osteoblasts in vitro: morphology, cytotoxicity, and oxidative stress.
Topics: Catalase; Cells, Cultured; Chromium; Cobalt; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Ions; Osteoblasts; Oxidation-Reduction; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2006 |
Modified montmorillonite as vector for gene delivery.
Topics: Aluminum; Bentonite; Cations; Cells, Cultured; Deoxyribonucleases; DNA; Electrophoresis; Endocytosis; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Humans; Hydrogen-Ion Concentration; Silicon; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2006 |
Secalonic acid D; A cytotoxic constituent from marine lichen-derived fungus Gliocladium sp. T31.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; DNA Fragmentation; Gliocladium; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Xanthones | 2006 |
Inhibitory effect of curcumin on WT1 gene expression in patient leukemic cells.
Topics: Adolescent; Antineoplastic Agents; Cell Line, Tumor; Child; Child, Preschool; Curcumin; Electrophoresis, Polyacrylamide Gel; Female; Gene Expression Regulation, Neoplastic; Genes, Wilms Tumor; Humans; Infant; K562 Cells; Leukemia; Male; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2006 |
In vitro effects of nitric oxide synthase inhibitor L-NAME on oral squamous cell carcinoma: a preliminary study.
Topics: Acridine Orange; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Gentian Violet; Humans; In Situ Hybridization; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrous Oxide; RNA; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Tumor Cells, Cultured | 2006 |
Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Transcription Factor RelA; Transfection; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Osteoblast behaviour on in situ photopolymerizable three-dimensional scaffolds based on D, L-lactide, epsilon-caprolactone and trimethylene carbonate.
Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Biomechanical Phenomena; Bone and Bones; Bone Marrow Cells; Bone Substitutes; Caproates; Cell Adhesion; Cell Differentiation; Cells, Cultured; Dioxanes; Extracellular Matrix; Fibroblasts; Lactones; Microscopy, Electron, Transmission; Osteoblasts; Osteocalcin; Polyesters; Polymers; Rats; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2006 |
Effect of dendritic cell vaccine against a tongue squamous cell cancer cell line (Tca8113) in vivo and in vitro.
Topics: Animals; Cancer Vaccines; Carcinoma, Squamous Cell; Cell Line, Tumor; Coloring Agents; Dendritic Cells; Disease Models, Animal; Disease Progression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunophenotyping; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Tumor Necrosis Factor-alpha | 2006 |
Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Glutathione; Humans; Hybrid Cells; Isoenzymes; Liver; Rats; Tetrazolium Salts; Thiazoles | 2006 |
Induced expression of insulin-like growth factor-1 by amniotic membrane-conditioned medium in cultured human corneal epithelial cells.
Topics: Amnion; Blotting, Western; Cell Proliferation; Cells, Cultured; Culture Media, Conditioned; DNA; Dose-Response Relationship, Drug; Epithelium, Corneal; Female; Humans; Insulin-Like Growth Factor I; Phosphorylation; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2006 |
Human serum reduces mitomycin-C cytotoxicity in human tenon's fibroblasts.
Topics: Annexin A5; Antibiotics, Antineoplastic; Apoptosis; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; DNA; Fascia; Fibroblasts; Flow Cytometry; Growth Substances; Humans; L-Lactate Dehydrogenase; Mitomycin; Serum; Tetrazolium Salts; Thiazoles | 2006 |
A new cytotoxic lanostane triterpenoid from the basidiomycete Hebeloma versipelle.
Topics: Antibiotics, Antineoplastic; Basidiomycota; Cell Division; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Humans; Lanosterol; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2005 |
Celecoxib induces dose dependent growth inhibition in nasopharyngeal carcinoma cell lines independent of cyclooxygenase-2 expression.
Topics: Blotting, Western; Celecoxib; Cell Division; Cell Line, Tumor; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Nasopharyngeal Neoplasms; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Tetrazolium Salts; Thiazoles | 2005 |
Cytostatic and cytotoxic effects of cyclooxygenase inhibitors and their synergy with docosahexaenoic acid on the growth of human skin melanoma A-375 cells.
Topics: Antineoplastic Agents; Aspirin; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Drug Synergism; Humans; Indomethacin; Melanoma, Experimental; Piroxicam; Skin Neoplasms; Tetrazolium Salts; Thiazoles | 2005 |
Short-interfering RNA-mediated silencing of thioredoxin reductase 1 alters the sensitivity of HeLa cells toward cadmium.
Topics: Arsenic Poisoning; Blotting, Northern; Cadmium Poisoning; Cell Death; Gene Silencing; HeLa Cells; Humans; Hydrogen Peroxide; Mercury Poisoning; Oxidants; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase; Transfection | 2006 |
Three new and antitumor anthraquinone glycosides from Lasianthus acuminatissimus MERR.
Topics: Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Rubiaceae; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
Three abietane diterpenes and two diterpenes incorporated sesquiterpenes from the bark of Cryptomeria japonica.
Topics: Abietanes; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cryptomeria; Drug Screening Assays, Antitumor; Escherichia coli; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Bark; Sesquiterpenes; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2006 |
Synthesis and PPAR-gamma ligand-binding activity of the new series of 2'-hydroxychalcone and thiazolidinedione derivatives.
Topics: Chalcone; Chalcones; Indicators and Reagents; Ligands; Luciferases; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transfection | 2006 |
Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes.
Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Cell Count; Cells, Cultured; Cerebellum; Drug Interactions; Enzyme Inhibitors; Ethylmaleimide; Glutathione; Mercury Poisoning, Nervous System; Methylmercury Compounds; Mice; Mitochondria; Neurons; Oxidoreductases; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes.
Topics: Amyloid beta-Peptides; Animals; Apoptosis Regulatory Proteins; Blotting, Western; Brain; Cell Death; Cell Fractionation; Cell Nucleus; Cytosol; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; MAP Kinase Kinase 4; Neuropeptides; Oligodendroglia; Phosphorylation; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sphingomyelin Phosphodiesterase; Sphingosine; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2006 |
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Ganglia, Sympathetic; Glial Cell Line-Derived Neurotrophic Factor; Immunoprecipitation; Membrane Microdomains; Membrane Proteins; Nerve Growth Factor; Neurons; Oligopeptides; Proteasome Endopeptidase Complex; Protein Transport; Proto-Oncogene Proteins c-ret; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Ubiquitin | 2006 |
Cytotoxicity assessment of gliotoxin and penicillic acid in Tetrahymena pyriformis.
Topics: Adenosine Triphosphate; Animals; Cell Proliferation; Cytotoxins; Gliotoxin; Oxygen; Penicillic Acid; Tetrahymena pyriformis; Tetrazolium Salts; Thiazoles | 2006 |
Activated microglial supernatant induced motor neuron cytotoxicity is associated with upregulation of the TNFR1 receptor.
Topics: Animals; Antibodies; Cell Count; Cell Death; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluorescent Antibody Technique; Lipopolysaccharides; Mice; Microglia; Motor Neurons; Nitric Oxide; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2006 |
The immunostimulating effect of bacterial genomic DNA on the innate immune responses of bivalve mussel, Hyriopsis cumingii Lea.
Topics: Acid Phosphatase; Adjuvants, Immunologic; Aeromonas hydrophila; Animals; Catechol Oxidase; DNA, Bacterial; Enzyme Induction; Enzyme Precursors; Escherichia coli; Hemocytes; Hemolymph; Immunity, Innate; Lipopolysaccharides; Muramidase; Superoxides; Tetrazolium Salts; Thiazoles; Time Factors; Unionidae | 2006 |
Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzophenanthridines; Berberine Alkaloids; CHO Cells; Cricetinae; Cricetulus; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Head Movements; Hindlimb Suspension; Inhibitory Concentration 50; Male; Mice; Mice, Inbred BALB C; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Serotonin Plasma Membrane Transport Proteins; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Effect of a standardized extract of red orange juice on proliferation of human prostate cells in vitro.
Topics: Animals; Artemia; Biological Assay; Cell Line; Cell Proliferation; Citrus sinensis; Cricetinae; Cricetulus; Epithelial Cells; Fibroblasts; Humans; Male; Phytotherapy; Plant Extracts; Prostate; Prostatic Hyperplasia; Tetrazolium Salts; Thiazoles; Trypan Blue | 2006 |
Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Apoptosis; Aspartic Acid Endopeptidases; Blotting, Western; Caspases; Cell Line, Tumor; Cell Survival; Chromatin; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoprecipitation; Luciferases; Membrane Proteins; Multiprotein Complexes; Mutation; Neuroblastoma; Peptide Fragments; Presenilin-1; Protein Structure, Tertiary; Staurosporine; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Synthesis and cytotoxic activity of substituted 2-phenyl-3-hydroxy-4(1H)-quinolinones-7-carboxylic acids and their phenacyl esters.
Topics: Antineoplastic Agents; Biological Availability; Carboxylic Acids; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Esters; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Quinolines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2006 |
Effects of sonic energy on monospecific biofilms of cariogenic microorganisms.
Topics: Animals; Biofilms; Cattle; Colorimetry; Coloring Agents; Dental Caries; Dental Enamel; Dental Plaque; Humans; Lactobacillus acidophilus; Rheology; Saliva, Artificial; Sonication; Streptococcus; Streptococcus mutans; Tetrazolium Salts; Thiazoles; Time Factors; Toothbrushing; Veillonella | 2006 |
Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide.
Topics: Analysis of Variance; Animals; Cell Communication; Cell Death; Cell Line; Cell Survival; Coculture Techniques; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Hypothermia; Immunohistochemistry; Interferon-gamma; Isothiuronium; Lipopolysaccharides; Mice; Microglia; Neuroblastoma; Neurons; Nitric Oxide; Radioimmunoassay; Tetrazolium Salts; Thiazoles | 2006 |
Thioviridamide, a novel apoptosis inducer in transformed cells from Streptomyces olivoviridis.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Culture Media; Fermentation; Fibroblasts; Peptides, Cyclic; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Streptomyces; Tetrazolium Salts; Thiazoles; Thioamides | 2006 |
Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation.
Topics: Analysis of Variance; Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavanones; Immunohistochemistry; Ketamine; Minocycline; N-Methylaspartate; Neuroprotective Agents; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Consumption of redox energy by glutathione metabolism contributes to hypoxia/ reoxygenation-induced injury in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Buthionine Sulfoximine; Cell Hypoxia; Cells, Cultured; Glutathione; Glycogen; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins.
Topics: Animals; Annexin A5; Apoptosis; Benzopyrans; Caspases; Cell Survival; DNA Fragmentation; Flow Cytometry; Humans; Indicators and Reagents; Jurkat Cells; Membrane Potentials; Mitochondria; Mycotoxins; Poly(ADP-ribose) Polymerases; Rats; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2006 |
Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Proliferation; Cell Survival; Cordyceps; Cytochromes c; DNA Fragmentation; DNA, Neoplasm; Electrophoresis; Enzyme Activation; HL-60 Cells; Humans; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles | 2006 |
Phenolic constituents of Malus doumeri var. formosana in the field of skin care.
Topics: Biphenyl Compounds; Caseins; Cells, Cultured; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Free Radical Scavengers; Kinetics; Malus; Metalloproteases; Phenols; Picrates; Plant Extracts; Skin Care; Superoxides; Tetrazolium Salts; Thiazoles; Xanthine Oxidase | 2006 |
Sesquiterpenes with various carbon skeletons from Ligularia virgaurea spp. oligocephala.
Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Cell Line, Tumor; Etoposide; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2006 |
Antimetastatic activity of Sulforaphane.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen; Electrophoresis, Polyacrylamide Gel; gamma-Glutamyltransferase; Hexosamines; Hydroxyproline; Isothiocyanates; Lung; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; N-Acetylneuraminic Acid; Neoplasm Metastasis; Sulfoxides; Survival Analysis; Tetrazolium Salts; Thiazoles; Thiocyanates; Thymidine; Uronic Acids | 2006 |
Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Flow Cytometry; Fluorouracil; Genes, bcl-2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2006 |
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer.
Topics: Agar; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin B; Cyclin B1; Cyclin D1; Down-Regulation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Plasmids; Ribosomal Proteins; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2006 |
Enhanced liver targeting of 5-fluorouracil using galactosylated human serum albumin as a carrier molecule.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fluorouracil; Galactose; Humans; Iodine Radioisotopes; Isotope Labeling; Liver; Male; Mice; Rabbits; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Tissue Distribution | 2006 |
Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature.
Topics: 8,11,14-Eicosatrienoic Acid; Annexin A5; Antibodies, Blocking; Apoptosis; Benzimidazoles; Blotting, Western; Calcium; Cardiotonic Agents; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Coronary Vessels; Culture Media, Serum-Free; Endothelial Cells; Endothelium, Vascular; fas Receptor; Fluorescent Dyes; Humans; Isomerism; Propidium; Pulmonary Circulation; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Hydralazine rescues PC12 cells from acrolein-mediated death.
Topics: Acrolein; Adenosine Triphosphate; Analysis of Variance; Animals; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Glutathione; Hydralazine; L-Lactate Dehydrogenase; Neuroprotective Agents; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles | 2006 |
Acrolein-mediated mechanisms of neuronal death.
Topics: Acrolein; Animals; Calpain; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Immunohistochemistry; Microscopy, Atomic Force; Microtubules; Mitochondria; Nerve Growth Factor; Neurons; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Apotransferrin decreases the response of oligodendrocyte progenitors to PDGF and inhibits the progression of the cell cycle.
Topics: Animals; Antimetabolites; Apoproteins; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cyclin-Dependent Kinases; Depression, Chemical; DNA; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; G1 Phase; Immunohistochemistry; Oligodendroglia; Platelet-Derived Growth Factor; Rats; S Phase; Stem Cells; Tetrazolium Salts; Thiazoles; Transferrin | 2006 |
Water gelation of an amino acid-based amphiphile.
Topics: Amino Acids; Anilino Naphthalenesulfonates; Cell Survival; Circular Dichroism; Cross-Linking Reagents; Fluorescence; HeLa Cells; Humans; Hydrogels; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning Transmission; Molecular Conformation; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles; Water | 2006 |
AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Neurons; Potassium; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation | 2006 |
Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.
Topics: Animals; Binding, Competitive; Cell Line; Chlordecone; CHO Cells; Cricetinae; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gene Expression; Genes, Reporter; HeLa Cells; Humans; Methoxychlor; Pesticide Residues; Pesticides; Plasmids; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Novel tetrahydroisoquinolin-ethyl-phenylamine based multidrug resistance inhibitors with broad-spectrum modulating properties.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzamides; Cell Line, Tumor; Cell Survival; Daunorubicin; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Isoquinolines; Mitoxantrone; Neoplasm Proteins; ortho-Aminobenzoates; Phthalic Acids; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
Inhibition of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) endocytosis by ouabain in human endothelial cells.
Topics: Cell Proliferation; Cells, Cultured; Cholesterol; Endocytosis; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Ouabain; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; src-Family Kinases; Tetrazolium Salts; Thiazoles; Umbilical Cord | 2006 |
Preventive effect of Ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kappaB in RAW 264.7 cells.
Topics: Animals; Blotting, Western; Cell Line; Cell Survival; Cyclooxygenase 2 Inhibitors; Dinoprostone; Electrophoretic Mobility Shift Assay; Ginkgo biloba; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
The cytotoxic saponin from heat-processed Achyranthes fauriei roots.
Topics: Achyranthes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Hot Temperature; Humans; Light; Plant Roots; Saponins; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2006 |
Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cyclic GMP; Cyclic N-Oxides; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Gene Expression; Glial Fibrillary Acidic Protein; HIV Envelope Protein gp120; Imidazoles; Lipopolysaccharides; Lysine; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thionucleotides; Time Factors | 2006 |
Biodegradable porous calcium polyphosphate scaffolds for the three-dimensional culture of dental pulp cells.
Topics: Apoptosis; Biocompatible Materials; Biodegradation, Environmental; Calcium Phosphates; Cell Adhesion; Cell Culture Techniques; Cell Movement; Cell Survival; Coloring Agents; Dental Pulp; DNA; Durapatite; Humans; Microscopy, Confocal; Microscopy, Electron, Scanning; Polyphosphates; Porosity; Secretory Vesicles; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2006 |
The effects of biocides (antiseptics and disinfectants) on the endospores of Rhinosporidium seeberi.
Topics: Animals; Anti-Infective Agents, Local; Disinfectants; Evans Blue; Humans; Parasitic Sensitivity Tests; Rhinosporidiosis; Rhinosporidium; Spores, Protozoan; Tetrazolium Salts; Thiazoles | 2006 |
In vitro comparison of the cytotoxicity of two orthodontic composite resins.
Topics: Acrylic Resins; Animals; Cell Survival; Colorimetry; Coloring Agents; Composite Resins; Culture Media; Dental Bonding; Drug Storage; Humans; In Vitro Techniques; Light; Materials Testing; Mice; Orthodontic Brackets; Photochemistry; Polyurethanes; Steel; Swiss 3T3 Cells; Tetrazolium Salts; Thiazoles; Tooth | 2006 |
Cryopreservation of Crassostrea gigas vesicular cells: viability and metabolic activity.
Topics: Animals; Cell Survival; Crassostrea; Cryopreservation; Glucose; Glycogen; Tetrazolium Salts; Thiazoles | 2006 |
Correlation between pharmacological efficacy of cyclosporine A and tacrolimus, evaluated by lymphocyte immunosuppressant-sensitivity test (LIST) with MTT assay procedure in renal transplant recipients.
Topics: Adult; Calcineurin Inhibitors; Cyclosporine; Female; Graft Rejection; Humans; Immunoassay; Immunosuppressive Agents; Kidney Transplantation; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Tacrolimus; Tetrazolium Salts; Thiazoles | 2006 |
Evaluation of MTT assay for measurement of emodin-induced cytotoxicity.
Topics: Cell Line; Dose-Response Relationship, Immunologic; Emodin; Enzyme Inhibitors; Formazans; Humans; Muscle, Smooth, Vascular; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2006 |
Fullerene-based amino acid nanoparticle interactions with human epidermal keratinocytes.
Topics: Amino Acids; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Fullerenes; Humans; Keratinocytes; Microscopy, Electron, Transmission; Nanoparticles; Tetrazolium Salts; Thiazoles; Vacuoles | 2006 |
Antitumor effect of antisense ornithine decarboxylase adenovirus on human lung cancer cells.
Topics: Adenoviridae; Apoptosis; Biotin; Cell Line, Tumor; Cell Proliferation; Gene Transfer Techniques; Genetic Therapy; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Neoplasm Invasiveness; Oligonucleotides, Antisense; Ornithine Decarboxylase; Tetrazolium Salts; Thiazoles | 2006 |
TRPC1 protects human SH-SY5Y cells against salsolinol-induced cytotoxicity by inhibiting apoptosis.
Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Calcium; Cell Count; Cell Line, Tumor; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Microscopy, Confocal; Neuroblastoma; Proteins; Tetrazolium Salts; Thiazoles; Time Factors; TRPC Cation Channels | 2006 |
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.
Topics: Adenosine Triphosphate; Amyloid beta-Peptides; Androstenes; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cells, Cultured; Cerebral Cortex; Cholesterol; Gas Chromatography-Mass Spectrometry; Glutathione; Lipid Peroxidation; Membrane Potentials; Mice; Neurodegenerative Diseases; Neurons; Oxidative Stress; Proteasome Endopeptidase Complex; Tetrazolium Salts; Thiazoles | 2006 |
Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription.
Topics: Animals; Anthracenes; Aplysia; Apoptosis; Axotomy; Blotting, Western; Cells, Cultured; Cloning, Molecular; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Functional Laterality; Ganglia, Invertebrate; Green Fluorescent Proteins; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Microinjections; Neurons, Afferent; Protein Binding; Serine; Synapses; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2006 |
Characterization of human dopamine responsive protein DRG-1 that binds to p75NTR-associated cell death executor NADE.
Topics: Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; Cell Cycle; Cell Division; Cell Proliferation; Chlorocebus aethiops; Chromosome Mapping; COS Cells; Down-Regulation; Flow Cytometry; Glutathione; GTP-Binding Proteins; Humans; Hybridization, Genetic; Immunoprecipitation; Molecular Sequence Data; PC12 Cells; Plasmids; Rats; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Tissue Distribution; Transfection | 2006 |
Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Apoptosis; Case-Control Studies; Caspase 3; Cells, Cultured; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Extracellular Fluid; Family Health; Fibroblasts; Humans; Middle Aged; Oxidative Stress; Plaque, Amyloid; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
OPC-12759 increases proliferation of cultured rat conjunctival goblet cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Cell Proliferation; Cells, Cultured; Coloring Agents; Conjunctiva; Goblet Cells; Histocytochemistry; Keratin-7; Keratins; Ki-67 Antigen; Male; Mucin 5AC; Mucins; Quinolones; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2006 |
Synthesis and in vitro cytotoxicity of haloderivatives of noscapine.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Humans; Indicators and Reagents; Kinetics; Noscapine; Tetrazolium Salts; Thiazoles | 2006 |
Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death.
Topics: Blotting, Western; Cell Count; Cell Culture Techniques; Cell Differentiation; Cell Survival; Cytoprotection; Diet; Dose-Response Relationship, Drug; Flavonoids; Heme Oxygenase-1; Humans; Hydrogen Peroxide; NF-E2-Related Factor 2; Oxidative Stress; Pigment Epithelium of Eye; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 2006 |
Mature pig oligodendrocytes rapidly process human recombinant pro-nerve growth factor and do not undergo cell death.
Topics: Animals; Blotting, Western; Cell Death; Cells, Cultured; Endocytosis; Humans; Immunohistochemistry; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Regeneration; Oligodendroglia; Protein Precursors; Recombinant Proteins; Signal Transduction; Swine; Tetrazolium Salts; Thiazoles | 2006 |
The synthesis of L-carvone and limonene derivatives with increased antiproliferative effect and activation of ERK pathway in prostate cancer cells.
Topics: Actins; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclohexane Monoterpenes; Cyclohexenes; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Humans; Indicators and Reagents; Limonene; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mitogen-Activated Protein Kinases; Monoterpenes; Prostatic Neoplasms; Signal Transduction; Structure-Activity Relationship; Terpenes; Tetrazolium Salts; Thiazoles | 2006 |
The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells.
Topics: Analysis of Variance; Animals; Blotting, Western; Bromodeoxyuridine; Butadienes; Caspase 3; Cell Count; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Mice; Nitriles; Tetrazolium Salts; Thiazoles | 2006 |
Cadmium-induced apoptosis in rat hepatocytes does not necessarily involve caspase-dependent pathways.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Bisbenzimidazole; Cadmium; Caspase 3; Caspases; Cell Separation; Cell Survival; Cells, Cultured; Chromatin; Cytochromes c; Cytosol; DNA; DNA Fragmentation; Hepatocytes; Male; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Recovery after short-term bilirubin exposure in human NT2-N neurons.
Topics: Apoptosis; Bilirubin; Caspase Inhibitors; Cell Death; Cell Line; Cell Nucleus; Culture Media, Serum-Free; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Humans; Neurons; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles | 2006 |
Cyclooxygenase-independent effects of aspirin on HT-29 human colon cancer cells, revealed by oligonucleotide microarrays.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biotechnology; Cluster Analysis; Colonic Neoplasms; Cyclooxygenase 2; Genome; HT29 Cells; Humans; Microscopy, Electron; Oligonucleotide Array Sequence Analysis; Phylogeny; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Light; Mice; Oxygen Consumption; Photochemotherapy; Photosensitizing Agents; Porphyrins; Protoporphyrins; Pyrimidinones; Tetrazolium Salts; Thiazoles | 2006 |
Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment.
Topics: Antimetabolites, Antineoplastic; Base Sequence; Biliary Tract Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Epigenesis, Genetic; Fluorouracil; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Sequence Data; Protein Synthesis Inhibitors; Tetrazolium Salts; Thiazoles | 2006 |
Growth inhibition and apoptosis induction in ovarian cancer cells.
Topics: Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Female; Gemcitabine; Genes, p53; Humans; Ovarian Neoplasms; Paclitaxel; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2006 |
Application of colorimetric assays to assess viability, growth and metabolism of hydrogel-encapsulated cells.
Topics: Alginates; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Colorimetry; Glucuronic Acid; Hexuronic Acids; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; L-Lactate Dehydrogenase; Mice; Rats; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2006 |
Synthesis, physicochemical characterization and preliminary pharmacological in vitro evaluation of two novel cytotoxic benzophenone-linked 3,3-dimethyltriazenes.
Topics: Antineoplastic Agents; Benzophenones; Cell Line; Chemical Phenomena; Chemistry, Physical; DNA Fragmentation; DNA, Neoplasm; HL-60 Cells; Humans; Models, Molecular; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triazenes | 2006 |
Distinct effects of short- and long-term leptin treatment on glucose and fatty acid uptake and metabolism in HL-1 cardiomyocytes.
Topics: Animals; Carrier Proteins; CD36 Antigens; Cell Line; Deoxyglucose; Fatty Acid Transport Proteins; Fatty Acids; Glucose; Glycogen; Hypoglycemic Agents; Immunoblotting; Insulin; Lactic Acid; Leptin; Mice; Myocytes, Cardiac; Oxidation-Reduction; Receptors, Leptin; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2006 |
Ex vivo activity of thalidomide in childhood acute leukemia.
Topics: Angiogenesis Inhibitors; Cell Cycle; Child; Child, Preschool; Cytarabine; Female; Humans; Immunophenotyping; Infant; Leukemia, Myeloid, Acute; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Tetrazolium Salts; Thalidomide; Thiazoles | 2006 |
Use of murine embryonic stem cells in embryotoxicity assays: the embryonic stem cell test.
Topics: 3T3 Cells; Animals; Cell Culture Techniques; Cell Differentiation; Cell Line; Drug Evaluation, Preclinical; Embryo, Mammalian; Flow Cytometry; Mice; Myocytes, Cardiac; Myosin Heavy Chains; Pluripotent Stem Cells; Solvents; Staining and Labeling; Teratogens; Tetrazolium Salts; Thiazoles | 2006 |
Inhibition of human IAPP fibril formation does not prevent beta-cell death: evidence for distinct actions of oligomers and fibrils of human IAPP.
Topics: Adenoviridae; Amyloid beta-Protein Precursor; Animals; Apoptosis; Benzothiazoles; Blotting, Western; Cell Death; Coloring Agents; DNA, Complementary; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Insulin-Secreting Cells; Islets of Langerhans; Propidium; Rats; Rats, Sprague-Dawley; Rifampin; Tetrazolium Salts; Thiazoles | 2006 |
Polymeric gene transfection on insulin-secreting cells: sulfonylurea receptor-mediation and transfection medium effect.
Topics: Amino Acids; Animals; ATP-Binding Cassette Transporters; Cell Survival; Culture Media; DNA; Insulin; Insulinoma; Pancreatic Neoplasms; Particle Size; Polylysine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Reproducibility of Results; Sulfonylurea Compounds; Sulfonylurea Receptors; Tetrazolium Salts; Thiazoles; Transfection; Vitamin E | 2006 |
The neurotrophic factor artemin promotes pancreatic cancer invasion.
Topics: Adenocarcinoma; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; Hypertrophy; Immunohistochemistry; Neoplasm Invasiveness; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Pain; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Prospective Studies; Tetrazolium Salts; Thiazoles | 2006 |
A preliminary investigation of cell growth after irradiation using a modulated x-ray intensity pattern.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Gentian Violet; Humans; Lung Neoplasms; Radiometry; Radiotherapy, Intensity-Modulated; Tetrazolium Salts; Thiazoles; X-Rays | 2006 |
Calcium salicylate-mediated apoptosis in human HT-1080 fibrosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Indicators and Reagents; p21-Activated Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Salicylates; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2006 |
Antibacterial, antiviral, antiproliferative and apoptosis-inducing properties of Brackenridgea zanguebarica (Ochnaceae).
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Antiviral Agents; Apoptosis; Bacteria; Cell Line, Tumor; Chromatography, High Pressure Liquid; Flavonoids; Gram-Positive Bacteria; HL-60 Cells; Humans; Jurkat Cells; Microbial Sensitivity Tests; Ochnaceae; Plant Bark; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Tannins; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Viruses | 2006 |
Mitogenic and apoptotic actions of epidermal growth factor on neuroblastoma cells are concentration-dependent.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Online measurement of oxygen consumption by goat bone marrow stromal cells in a combined cell-seeding and proliferation perfusion bioreactor.
Topics: Animals; Biocompatible Materials; Bioreactors; Bone Marrow Cells; Calcium Phosphates; Cell Proliferation; Cell Survival; Computers; Goats; Oxygen; Oxygen Consumption; Perfusion; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2006 |
Role of CDK5 in neuroprotection from serum deprivation by mu-opioid receptor agonist.
Topics: Animals; Blotting, Western; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Cyclin-Dependent Kinase 5; Drug Interactions; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Gene Expression Regulation; Hippocampus; Humans; Mutagenesis; Naloxone; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Serum; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2006 |
ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells.
Topics: Adenoviridae; Animals; Apoptosis; Caspase 3; Cell Nucleus; Chromones; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Histones; Hydrogen Peroxide; Kidney; Kidney Tubules, Proximal; Morpholines; Oncogene Protein v-akt; Oxidants; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Rabbits; Tetrazolium Salts; Thiazoles | 2007 |
Phenolic glycosides from Exostema mexicanum leaves.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chromatography, Thin Layer; Glycosides; Humans; Magnetic Resonance Spectroscopy; Mexico; Phenols; Plant Leaves; Rubiaceae; Spectrometry, Mass, Fast Atom Bombardment; Tetrazolium Salts; Thiazoles | 2006 |
In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; Doxorubicin; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, MDR; Humans; Liposomes; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Oligonucleotides, Antisense; Polyethylene Glycols; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2006 |
Cytotoxic activity of violacein in human colon cancer cells.
Topics: Apoptosis; Caco-2 Cells; Calcium; Caspase 3; Cell Death; Cell Survival; Colonic Neoplasms; Cytochromes c; Enzyme Activation; HT29 Cells; Humans; Indicators and Reagents; Indoles; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Chromatography, Affinity; Molecular Sequence Data; Oligopeptides; PC12 Cells; Peptide Fragments; Peptide Library; Peptides; Protein Structure, Quaternary; Rats; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2006 |
Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons.
Topics: Acidosis; Antibodies; Cell Hypoxia; Cell Line; Chemokine CCL2; Chemokine CCL5; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Gene Expression Regulation; Glucose; Humans; Hypoxia; Interleukin-8; Neurofilament Proteins; Neurons; Oxygen; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Mouse aldo-keto reductase AKR7A5 protects V79 cells against 4-hydroxynonenal-induced apoptosis.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line; Cricetinae; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Fibroblasts; Lipid Peroxidation; Mice; Mutagenicity Tests; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures.
Topics: Acetylcysteine; Analysis of Variance; Animals; Cell Count; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; gamma-Aminobutyric Acid; Immunohistochemistry; Mesencephalon; Neurons; Neurotoxins; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors; Tritium | 2006 |
Nanomolar cationic dendrimeric sulfadiazine as potential antitoxoplasmic agent.
Topics: Animals; Cations; Cell Membrane; Cell Survival; Chlorocebus aethiops; Dendrimers; Drug Carriers; Drug Delivery Systems; Humans; Polyamines; Solubility; Sulfadiazine; Tetrazolium Salts; Thiazoles; Toxoplasma; Toxoplasmosis; Vero Cells | 2006 |
Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells.
Topics: Acetylcysteine; Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Brain; Buthionine Sulfoximine; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Oxidative Stress; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2006 |
Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Calcium Channels; Calpain; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hypochlorous Acid; Lysosomes; Mice; Microscopy, Electron, Transmission; Neocortex; Neurons; Nifedipine; Oxidants; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Hydroxycamptothecin-induced apoptosis in hepatoma SMMC-7721 cells and the role of mitochondrial pathway.
Topics: Apoptosis; Apoptosis Inducing Factor; Camptothecin; Cell Line, Tumor; Cell Survival; Cytochromes c; Cytoplasm; DNA Fragmentation; Enzyme Inhibitors; Hepatocytes; Humans; Membrane Potential, Mitochondrial; Mitochondria; Tetrazolium Salts; Thiazoles | 2006 |
Pulmonary fibroblasts stimulate the proliferation of cell lines from human lung adenocarcinomas.
Topics: Adenocarcinoma; Amphiregulin; Animals; Antibodies, Blocking; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Cyclin D1; Cyclin E; EGF Family of Proteins; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Glycoproteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lung; Lung Neoplasms; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transforming Growth Factor alpha | 2006 |
Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721.
Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Shape; Colorimetry; DNA Fragmentation; DNA, Neoplasm; Flavanones; Humans; Propidium; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2006 |
Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion.
Topics: Allantoin; Angiogenesis Inhibitors; Animals; Artemisinins; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Culture Media, Conditioned; Down-Regulation; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Hypoxia; Membranes; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2006 |
Studies on the preparation, crystal structure and bioactivity of ginsenoside compound K.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biotransformation; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Crystallography, X-Ray; Cyclophosphamide; Humans; Mass Spectrometry; Mice; Models, Molecular; Panax; Quantitative Structure-Activity Relationship; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2006 |
Total synthesis and biological evaluation of (+)- and (-)-Butyl ester of rosmarinic acid.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Cinnamates; Depsides; Drug Screening Assays, Antitumor; Esters; Humans; In Vitro Techniques; Isodon; Lactic Acid; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Menthol; Microsomes, Liver; Molecular Conformation; Rats; Rosmarinic Acid; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment; Tetrazolium Salts; Thiazoles | 2006 |
Effect of 5alpha-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 8; Cell Survival; Dihydrotestosterone; Genes, bcl-2; Humans; In Vitro Techniques; Necrosis; Reverse Transcriptase Polymerase Chain Reaction; RNA; Skin; Testosterone; Tetrazolium Salts; Thiazoles | 2006 |
Characterization and osteoblast-like cell compatibility of porous scaffolds: bovine hydroxyapatite and novel hydroxyapatite artificial bone.
Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Bone and Bones; Bone Substitutes; Cattle; Cell Differentiation; Durapatite; Mice; Microscopy, Electron, Scanning; Osteoblasts; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2006 |
Thallium induces hydrogen peroxide generation by impairing mitochondrial function.
Topics: Algorithms; Animals; Cell Death; Cell Survival; Glutathione; Glutathione Transferase; Hydrogen Peroxide; Kinetics; Membrane Potentials; Mitochondria; Neurons; Oxidants; Oxidation-Reduction; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thallium; Thiazoles | 2006 |
Inhibitory effect of caffeic acid phenethyl ester on the growth of SW480 colorectal tumor cells involves beta-catenin associated signaling pathway down-regulation.
Topics: Animals; Apoptosis; beta Catenin; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Humans; Phenylethyl Alcohol; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Involvement of P53 and Bax/Bad triggering apoptosis in thioacetamide-induced hepatic epithelial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Survival; Endothelial Cells; Fibrosis; Gene Expression Regulation; Genes, p53; Humans; Liver; Rats; Tetrazolium Salts; Thiazoles; Thioacetamide; Tumor Suppressor Protein p53 | 2006 |
A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine.
Topics: Actins; Blotting, Western; Cell Line; Cell Survival; Cytarabine; Dipeptides; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Oxidopamine; Prolyl Oligopeptidases; Protease Inhibitors; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Reactive Oxygen Species; Serine Endopeptidases; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2006 |
Phase-sensitive polymer-based controlled delivery systems of leuprolide acetate: in vitro release, biocompatibility, and in vivo absorption in rabbits.
Topics: Animals; Antineoplastic Agents, Hormonal; Biocompatible Materials; Chemistry, Pharmaceutical; Data Interpretation, Statistical; Drug Compounding; Drug Delivery Systems; Intestinal Absorption; Lactic Acid; Leuprolide; Materials Testing; Polyesters; Polymers; Rabbits; Solubility; Testosterone; Tetrazolium Salts; Thiazoles | 2007 |
Preparation and targeted delivery of immunoliposomes bearing poly(ethylene glycol)-coupled humanized anti-hepatoma disulfide-stabilized Fv (hdsFv25) in vitro.
Topics: Antineoplastic Agents; Bee Venoms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Delivery Systems; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Immunoconjugates; Liposomes; Microscopy, Fluorescence; Particle Size; Polyethylene Glycols; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2006 |
Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; Down-Regulation; Drug Resistance, Neoplasm; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides; Phosphorylation; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
Effects of selective estrogen receptor modulator raloxifene plus 17-beta estradiol in aorta and mammary gland of female experimental atherosclerosis rabbits and possible involvement of ERK signal transduction pathway.
Topics: Animals; Aorta; Atherosclerosis; Blotting, Western; Drug Interactions; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Hyperplasia; Lipids; Mammary Glands, Animal; Muscle, Smooth, Vascular; Rabbits; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine | 2006 |
Oxidizing and reducing responses of granulocytes from type 2 diabetic patients.
Topics: Adult; Aged; Antioxidants; Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Granulocytes; Humans; Male; Middle Aged; Oxidation-Reduction; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
Initial in vitro biological response to contemporary endodontic sealers.
Topics: Acetone; Animals; BALB 3T3 Cells; Biocompatible Materials; Coloring Agents; Dimethylpolysiloxanes; Drug Combinations; Epoxy Resins; Ethanol; Gutta-Percha; Materials Testing; Methacrylates; Mice; Root Canal Filling Materials; Solvents; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2006 |
Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: involvement of ERK and p38 phosphorylation.
Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Count; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Guaiacol; In Situ Nick-End Labeling; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2006 |
Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Proliferation; Cell Survival; Cells, Cultured; Embryo, Mammalian; Gene Expression Regulation, Developmental; In Situ Nick-End Labeling; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Protein Isoforms; Receptor, trkB; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Statistics, Nonparametric; Stem Cells; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium | 2006 |
Determination of interleukin-1alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants.
Topics: Cell Line; Cell Survival; Cytokines; Humans; Interleukin-1alpha; Irritants; Keratinocytes; Lysine; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 2006 |
The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Blotting, Western; Cell Fractionation; Cell Line, Tumor; Cell Survival; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression; Humans; Neuroblastoma; Neurotoxins; Phosphorylation; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
In vivo and in vitro inhibitory effect of amniotic extraction on neovascularization.
Topics: Amnion; Angiogenesis Inhibitors; Animals; Blood Vessels; Blotting, Western; Burns, Chemical; Cell Proliferation; Cells, Cultured; Corneal Neovascularization; Dexamethasone; Endothelium, Vascular; Eye Burns; Eye Proteins; Female; Humans; Nerve Growth Factors; Pilot Projects; Rats; Rats, Sprague-Dawley; Serpins; Sodium Hydroxide; Tetrazolium Salts; Thiazoles; Tissue Extracts; Umbilical Veins | 2006 |
Insulin-like growth factor binding proteins: regulation in chronic active plaques in multiple sclerosis and functional analysis of glial cells.
Topics: Adult; Aged; Aged, 80 and over; Animals; Animals, Newborn; Cell Count; Cell Proliferation; Cells, Cultured; Female; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Proteins; Male; Middle Aged; Multiple Sclerosis; Neuroglia; Oligodendroglia; Postmortem Changes; Rats; Stem Cells; Tetrazolium Salts; Thiazoles | 2006 |
Experimental exposure of arsenic in cultured rat intestinal epithelial cells and cell line: toxicological consequences.
Topics: Animals; Arsenic; Arsenites; Cell Division; Cell Line; Cell Line, Transformed; Cell Membrane; Cell Shape; Cell Survival; Cells, Cultured; Epithelial Cells; Esterases; Indicators and Reagents; Intestinal Mucosa; Kinetics; Male; Oxidoreductases; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2007 |
PVP magnetic nanospheres: biocompatibility, in vitro and in vivo bleomycin release.
Topics: Animals; Antibiotics, Antineoplastic; Biocompatible Materials; Bleomycin; Chromatography, High Pressure Liquid; Female; Gamma Rays; Hemolysis; Magnetics; Male; Materials Testing; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning Transmission; Nanoparticles; Polyvinyl Alcohol; Povidone; Rabbits; Reference Standards; Tetrazolium Salts; Thiazoles; Tissue Distribution | 2007 |
Synthesis and antiproliferative activity in vitro of diacetylenic thioquinolines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Quinolines; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2006 |
A new cyclotetrapeptide from marine fungus Trichoderma reesei.
Topics: Amino Acids; Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Peptides, Cyclic; Tetrazolium Salts; Thiazoles; Trichoderma | 2006 |
Oxidized ATP decreases beta-actin expression and intracellular superoxide concentrations in RBA-2 type-2 astrocytes independently of P2X7 receptor.
Topics: Actins; Adenosine Triphosphate; Astrocytes; Blotting, Western; Caspase 1; Cell Line; Flow Cytometry; Fluorescent Antibody Technique; Humans; Intracellular Space; Oxidation-Reduction; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Superoxides; Tetrazolium Salts; Thiazoles | 2006 |
Evaluation of anticancer activity of 4-vinyl-1-arylsulfonylimidazolidinones.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Hydantoins; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vinyl Compounds | 2006 |
N-acetylcysteine attenuates TNF-alpha-induced human vascular endothelial cell apoptosis and restores eNOS expression.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Glutathione; Glutathione Peroxidase; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
Interleukin-1beta mediates GDNF up-regulation upon dopaminergic injury in ventral midbrain cell cultures.
Topics: Animals; Astrocytes; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Dopamine; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Glial Cell Line-Derived Neurotrophic Factor; Glial Fibrillary Acidic Protein; Hydrogen Peroxide; Immunohistochemistry; Interleukin-1beta; Levodopa; Mesencephalon; Neuroglia; Oxidants; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation; Ventral Tegmental Area | 2007 |
Evaluation of paclitaxel rearrangement involving opening of the oxetane ring and migration of acetyl and benzoyl groups.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Female; Humans; Indicators and Reagents; KB Cells; Magnetic Resonance Spectroscopy; Paclitaxel; Tetrazolium Salts; Thiazoles | 2007 |
Microfabrication of fractal polymeric structures for capillary morphogenesis: applications in therapeutic angiogenesis and in the engineering of vascularized tissue.
Topics: Algorithms; Biocompatible Materials; Capillaries; Cells, Cultured; Coculture Techniques; Endothelial Cells; Fractals; Genetic Vectors; Humans; Materials Testing; Neovascularization, Physiologic; Polyesters; Polymers; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Kallikreins; Transfection | 2007 |
Baclofen and potential therapeutic use: studies of neuronal survival.
Topics: Animals; Baclofen; Cell Survival; Cells, Cultured; Colorimetry; Data Interpretation, Statistical; Female; GABA Agonists; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Muscle Relaxants, Central; Neurons; Neuroprotective Agents; Pregnancy; Rats; Tetrazolium Salts; Thiazoles | 2006 |
Cell toxicity studies of albumin-based nanosized magnetic beads.
Topics: Albumins; Animals; Biotechnology; Cell Line; Ions; Magnetics; Mice; Microscopy, Electron, Transmission; Models, Molecular; Nanoparticles; Nanotechnology; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
[Effects of tyrosine kinase receptor B and brain-derived neurotrophic factor on chemoresistance in neuroblastoma].
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Microscopy, Electron, Transmission; Neuroblastoma; Receptor, trkB; Tetrazolium Salts; Thiazoles; Tretinoin | 2006 |
Effects of interactions of EGCG and Cd(2+) on the growth of PC-3 cells and their mechanisms.
Topics: Absorption; Animals; Anticarcinogenic Agents; Cadmium; Catechin; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Male; Prostatic Neoplasms; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Zinc | 2007 |
Genistein protects methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells.
Topics: Adult; Animals; Antimutagenic Agents; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Female; Genistein; Humans; Leukocytes, Mononuclear; Male; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
The contribution of DNA repair and antioxidants in determining cell type-specific resistance to oxidative stress.
Topics: Antioxidants; Catalase; Cell Line; Cell Survival; DNA Damage; DNA Repair; DNA, Mitochondrial; Humans; Hydrogen Peroxide; Mitosis; Oxidative Stress; Oxygen; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells.
Topics: Actins; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Division; Cell Proliferation; Cell Survival; Enediynes; Flow Cytometry; G1 Phase; G2 Phase; HL-60 Cells; Humans; Poly(ADP-ribose) Polymerases; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles | 2007 |
Cell cycle dependent regulation of deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5'-nucleotidase I activity in MOLT-4 cells.
Topics: 5'-Nucleotidase; Cell Cycle; Cell Line, Tumor; Culture Media, Serum-Free; Cytosol; Deoxycytidine Kinase; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway.
Topics: Aminoimidazole Carboxamide; Apoptosis; Caspase 9; Cell Line, Tumor; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fluorescent Dyes; Humans; Metformin; Mitochondria; Neuroblastoma; Purines; Ribonucleosides; Tetrazolium Salts; Thiazoles | 2006 |
A new generation of sterile and radiopaque impression materials: an in vitro cytotoxicity study.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Contrast Media; Dental Impression Materials; Fibroblasts; Gingiva; Humans; In Vitro Techniques; Materials Testing; Polyvinyls; Siloxanes; Sterilization; Tetrazolium Salts; Thiazoles; Viscosity | 2007 |
Vulnerability of neurons with mitochondrial dysfunction to oxidative stress is associated with down-regulation of thioredoxin.
Topics: Animals; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Electron Transport Complex IV; Enzyme Inhibitors; Female; Hydrogen Peroxide; Membrane Potentials; Mice; Mice, Inbred ICR; Mitochondria; Neurons; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sodium Azide; Tetrazolium Salts; Thiazoles; Thioredoxins; Time Factors | 2007 |
Neuroprotectant FK506 inhibits glutamate-induced apoptosis of astrocytes in vitro and in vivo.
Topics: Animals; Apoptosis; Astrocytes; Blotting, Western; Caspases; Cell Size; Cell Survival; Cells, Cultured; Cerebral Cortex; DNA Fragmentation; Enzyme Activation; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Glutamic Acid; In Situ Nick-End Labeling; Indoles; Infarction, Middle Cerebral Artery; Male; Membrane Potentials; Mitochondria; Neuroprotective Agents; Rats; Reperfusion Injury; Tacrolimus; Tetrazolium Salts; Thiazoles | 2006 |
L-carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Carnitine; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; Sialic Acids; Tetrazolium Salts; Thiazoles | 2007 |
Methods for isolation of endothelial and smooth muscle cells and in vitro proliferation assays.
Topics: Animals; Aorta; Cell Culture Techniques; Cell Proliferation; Collagen; Drug Combinations; Endothelial Cells; Humans; Laminin; Lung; Mice; Myocytes, Smooth Muscle; Proteoglycans; Skin; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Umbilical Veins | 2006 |
Cytotoxicity of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles in rat glioma cell lines using different assays.
Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Chemistry, Pharmaceutical; Chromatography, Gas; Doxorubicin; Enbucrilate; Excipients; Flow Cytometry; Glioma; L-Lactate Dehydrogenase; Microscopy, Confocal; Nanoparticles; Rats; Tetrazolium Salts; Thiazoles | 2006 |
Effects of glucose, insulin, and supernatant from pancreatic beta-cells on brain-pancreas relative protein in rat hippocampus.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Flow Cytometry; Glucose; Hippocampus; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Microscopy, Confocal; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2006 |
Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer.
Topics: Adult; Anilides; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Drug Design; Female; Humans; Indicators and Reagents; Isotope Labeling; Nitrobenzenes; Positron-Emission Tomography; Radiopharmaceuticals; Sulfonamides; Tetrazolium Salts; Thiazoles | 2007 |
Linker-modified triamine-linked acridine dimers: synthesis and cytotoxicity properties in vitro and in vivo.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; DNA; Humans; Indicators and Reagents; Intercalating Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred ICR; Mice, SCID; Nitrogen; Plasmids; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex.
Topics: Analysis of Variance; Androstanols; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dexamethasone; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Developmental; Glucocorticoids; Hydro-Lyases; Hypoxia; Male; Membrane Proteins; Mitochondrial Proteins; Mutagenesis; Neurons; Pregnancy; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Sex Factors; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2007 |
An efficient synthesis of quinoxaline derivatives from 4-chloro-4-deoxy-alpha-D-galactose and their cytotoxic activities.
Topics: Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Fucose; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Quinoxalines; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Amyloid-beta peptide affects viability but not differentiation of embryonic and adult rat hippocampal progenitor cells.
Topics: Amyloid beta-Peptides; Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Survival; Cells, Cultured; Female; Hippocampus; Immunohistochemistry; Microscopy, Fluorescence; Mitochondria; Neurons; Pregnancy; Rats; Rats, Inbred F344; Stem Cells; Tetrazolium Salts; Thiazoles | 2007 |
Nitric oxide regulates cell survival in purified cultures of avian retinal neurons: involvement of multiple transduction pathways.
Topics: Adenosine; Aminoquinolines; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Chick Embryo; Cyclic GMP; Cyclic N-Oxides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Penicillamine; Retina; Signal Transduction; Tetrazolium Salts; Thiazoles; Tritium | 2007 |
Monoclonal antibodies that target pathological assemblies of Abeta.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Antibody Specificity; Brain; Calmodulin-Binding Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Epitopes; Glial Fibrillary Acidic Protein; Humans; Immunoblotting; Immunohistochemistry; Mice; Neurons; Peptide Fragments; Protein Binding; Rabbits; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Epigallocatechin gallate inhibits nitric oxide-induced apoptosis in rat PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Catechin; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Voltage-Dependent Anion Channels | 2007 |
Electron transfer from NADH bound to horse liver alcohol dehydrogenase (NAD+ dependent dehydrogenase): visualisation of the activity in the enzyme crystals and adsorption of formazan derivatives by these crystals.
Topics: Acrolein; Adsorption; Alcohol Dehydrogenase; Animals; Catalysis; Crystallization; Diffusion; Electron Transport; Formazans; Horses; Kinetics; Liver; Methylphenazonium Methosulfate; Molecular Structure; NAD; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2007 |
Halichondria sulfonic acid, a new HIV-1 inhibitory guanidino-sulfonic acid, and halistanol sulfate isolated from the marine sponge Halichondria rugosa Ridley & Dendy.
Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; China; Crystallography, X-Ray; Enzyme-Linked Immunosorbent Assay; Guanidines; HIV-1; Inhibitory Concentration 50; Molecular Structure; Oceans and Seas; Porifera; Spectrophotometry, Infrared; Spectrum Analysis; Sterols; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2006 |
Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells.
Topics: Aminoglutethimide; Antineoplastic Agents; Apoptosis; beta-Cyclodextrins; Breast Neoplasms; Cell Survival; Chlorpromazine; Cytochalasin B; Doxorubicin; Endocytosis; Female; Flow Cytometry; Humans; Immunohistochemistry; Ki-67 Antigen; Kinetics; Liver; Lysosomes; Methacrylates; Microscopy, Confocal; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2007 |
Protective effects of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Hypoxia; Cell Line; Cell Survival; Coloring Agents; Myoblasts, Cardiac; NAD; Necrosis; Oxidative Stress; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2006 |
Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Campanulaceae; Cell Line, Tumor; Chaetomium; Circular Dichroism; Colonic Neoplasms; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Indole Alkaloids; K562 Cells; Magnetic Resonance Spectroscopy; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2006 |
Glucose induces MafA expression in pancreatic beta cell lines via the hexosamine biosynthetic pathway.
Topics: Animals; Cell Nucleus; Cell Survival; Cytosol; Gene Expression Regulation; Glucose; Glycosylation; Hexosamines; Insulin; Insulin-Secreting Cells; Maf Transcription Factors, Large; Mice; Models, Biological; N-Acetylglucosaminyltransferases; Tetrazolium Salts; Thiazoles | 2007 |
A new stilbene glucoside from the roots of Polygonum multiflorum Thunb.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glucosides; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Roots; Polygonum; Spectrophotometry, Ultraviolet; Stilbenes; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2006 |
The protective effects of phenolic constituents from Gastrodia elata on the cytotoxicity induced by KCl and glutamate.
Topics: Adenosine; Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Cell Survival; Ethyl Ethers; Excitatory Amino Acid Antagonists; Gastrodia; Glucosides; Glutamic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neuroprotective Agents; PC12 Cells; Phenols; Plant Extracts; Plant Tubers; Potassium Chloride; Rats; Tetrazolium Salts; Thiazoles | 2006 |
Extracellular ATP induces apoptotic signaling in human monocyte leukemic cells, HL-60 and F-36P.
Topics: Adenosine Triphosphate; Annexins; Apoptosis; Calcium; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorimetry; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Myeloid; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cytochromes c; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Floxuridine; Glial Fibrillary Acidic Protein; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Peptides, Cyclic; Pregnancy; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2007 |
Cytocompatibility of poly(acrylonitrile-co-N-vinyl-2-pyrrolidone) membranes with human endothelial cells and macrophages.
Topics: Acrylic Resins; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Endothelial Cells; Humans; Macrophages; Polymers; Polystyrenes; Polyvinyl Chloride; Pyrrolidinones; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2007 |
Application of cell penetrating peptide in magnetic resonance imaging of bone marrow mesenchymal stem cells.
Topics: Animals; Apoptosis; Bone Marrow Cells; Flow Cytometry; Gadolinium; Magnetic Resonance Imaging; Male; Mesenchymal Stem Cells; Peptides; Rats; Rats, Sprague-Dawley; Temperature; Tetrazolium Salts; Thiazoles | 2006 |
Identification of genes related to nasopharyngeal carcinoma with the help of pathway-based networks.
Topics: Base Sequence; Blotting, Western; Carcinoma; Cell Cycle; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Molecular Sequence Data; Nasopharyngeal Neoplasms; Oligonucleotide Array Sequence Analysis; ran GTP-Binding Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Synthesis and characterization of guanidinylated poly(propylene imine) dendrimers as gene transfection agents.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chlorocebus aethiops; COS Cells; Dendrimers; DNA; Electrochemistry; Electrophoresis, Agar Gel; Excipients; Gene Transfer Techniques; Guanidines; Humans; Light; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Plasmids; Scattering, Radiation; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Lipopeptide-based liposomes for DNA delivery into cells expressing neuropilin-1.
Topics: beta-Galactosidase; Blotting, Western; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cytomegalovirus; DNA; Flow Cytometry; Genes, Reporter; Green Fluorescent Proteins; Indicators and Reagents; Liposomes; Mass Spectrometry; Microscopy, Fluorescence; Neuropilin-1; Peptides; Plasmids; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Therapeutic potential of chlorotoxin-like neurotoxin from the Chinese scorpion for human gliomas.
Topics: Astrocytes; Cell Line, Tumor; Cell Proliferation; China; Defensins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Glioma; Humans; Inhibitory Concentration 50; Membrane Potentials; Patch-Clamp Techniques; Scorpion Venoms; Tetrazolium Salts; Thiazoles | 2007 |
Re-evaluation of tacrine hepatotoxicity using gel entrapped hepatocytes.
Topics: Albumins; Animals; Antidepressive Agents, Second-Generation; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Cytochrome P-450 CYP1A2; Female; Fluvoxamine; Gels; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycyrrhetinic Acid; Hepatocytes; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tacrine; Tetrazolium Salts; Thiazoles | 2007 |
The degree and kind of agglomeration affect carbon nanotube cytotoxicity.
Topics: Asbestos, Crocidolite; Carbon; Cell Line, Tumor; Cell Survival; DNA; Hexoses; Humans; Materials Testing; Nanotubes; Polyethylene Glycols; Spectroscopy, Near-Infrared; Tetrazolium Salts; Thiazoles | 2007 |
Synthesis and antitumour evaluation of peptidyl-like derivatives containing the 1,3-benzodioxole system.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Dioxoles; Drug Screening Assays, Antitumor; Embryo, Nonmammalian; Embryonic Development; Hemolysis; Humans; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Sea Urchins; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2007 |
Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: in vitro study.
Topics: Angiography; Animals; Apoptosis; Cell Death; Coloring Agents; Contrast Media; Gadolinium; Gadolinium DTPA; Iodine; Iopamidol; Kidney Tubules, Proximal; LLC-PK1 Cells; Mannitol; Meglumine; Necrosis; Organometallic Compounds; Swine; Tetrazolium Salts; Thiazoles; Trypan Blue | 2007 |
Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Survival; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Mice; Mutagenesis; Neurons; Potassium; Potassium Chloride; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine | 2007 |
The effect of SHJKS on cytokines production and NF-kappaB activation in the peripheral blood mononuclear cells of patients with cerebral infarction.
Topics: Aged; Anti-Inflammatory Agents; Biotransformation; Blotting, Western; Cell Nucleus; Cells, Cultured; Cerebral Infarction; Chromatography, High Pressure Liquid; Cytokines; Cytoplasm; Female; Humans; Indicators and Reagents; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; Middle Aged; Monocytes; NF-kappa B; Phytohemagglutinins; Plant Extracts; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
A study on medicinal plants from Malaysia focused on Acalypha siamensis Oliv. ex Gage. isolation and structure of a new tetraterpene, acalyphaser A.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Euphorbiaceae; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Models, Chemical; Plant Extracts; Terpenes; Tetrazolium Salts; Thiazoles | 2006 |
Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity.
Topics: Biotin; Cetrimonium; Cetrimonium Compounds; Citric Acid; Gold; Humans; K562 Cells; Metal Nanoparticles; Microscopy, Electron; Nanoparticles; Nanotechnology; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
RNA interference-mediated inhibition of brain-derived neurotrophic factor expression increases cocaine's cytotoxicity in cultured cells.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cell Death; Cell Line, Tumor; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Down-Regulation; Gene Expression Regulation; Humans; Neurons; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
New and simple plate test for screening relative transfructosylation activity of fungi.
Topics: Ampyrone; Ascomycota; beta-Fructofuranosidase; Carbohydrate Dehydrogenases; Chromogenic Compounds; Colorimetry; Fructose; Fungal Proteins; Fungi; Glucose; Glucose Oxidase; Glycosylation; Hexosyltransferases; Indicators and Reagents; Industrial Microbiology; Methylphenazonium Methosulfate; Mycology; Oligosaccharides; Peroxidase; Phenol; Reproducibility of Results; Species Specificity; Tetrazolium Salts; Thiazoles | 2006 |
Internalization is essential for the antiapoptotic effects of exogenous thymosin beta-4 on human corneal epithelial cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspases; Cell Culture Techniques; Cell Line, Transformed; Cytochalasin D; Endocytosis; Epithelium, Corneal; Fas Ligand Protein; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Humans; Hydrogen Peroxide; Maximum Tolerated Dose; Rabbits; Recombinant Proteins; Simian virus 40; Tetrazolium Salts; Thiazoles; Thymosin | 2007 |
Cytotoxic effect of spermine on retinal pigment epithelial cells.
Topics: Animals; Annexin A5; Apoptosis; Cattle; Cell Culture Techniques; Cell Proliferation; Colorimetry; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Microscopy, Confocal; Ornithine; Pigment Epithelium of Eye; Propidium; Spermine; Tetrazolium Salts; Thiazoles; Thymidine | 2007 |
Saponins from Tribulus terrestris L are less toxic for normal human fibroblasts than for many cancer lines: influence on apoptosis and proliferation.
Topics: Actins; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dual Specificity Phosphatase 1; Fibroblasts; Humans; Immediate-Early Proteins; Immunoblotting; Inhibitory Concentration 50; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proteins; Putrescine; Saponins; Signal Transduction; Spermidine; Spermine; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tribulus; Tritium | 2007 |
Collagen gel contractility is enhanced in human endometriotic stromal cells: a possible mechanism underlying the pathogenesis of endometriosis-associated fibrosis.
Topics: Actins; Adult; Amides; Cell Differentiation; Collagen; Endometriosis; Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibrosis; Gels; Humans; Intracellular Signaling Peptides and Proteins; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Stromal Cells; Tetrazolium Salts; Thiazoles | 2007 |
Interleukin-12 expression enhances vesicular stomatitis virus oncolytic therapy in murine squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Coloring Agents; Disease Models, Animal; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Vectors; Injections, Intralesional; Interleukin-12; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Mouth Floor; Mouth Neoplasms; Oncolytic Virotherapy; Oncolytic Viruses; RNA, Viral; Survival Rate; Tetrazolium Salts; Thiazoles; Vesicular stomatitis Indiana virus; Virus Replication | 2007 |
Self-gelling primaquine-gum arabic conjugate: an injectable controlled delivery system for primaquine.
Topics: Animals; Antimalarials; Biocompatible Materials; Cell Line; Cross-Linking Reagents; Drug Delivery Systems; Drug Design; Gum Arabic; Kinetics; Mice; Models, Chemical; Polymers; Polysaccharides; Primaquine; Tetrazolium Salts; Thiazoles | 2007 |
Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells.
Topics: Androstadienes; Animals; Cations; Cell Survival; Chlorpromazine; Cholesterol; Clathrin; Dendrimers; Dextrans; Drug Delivery Systems; Endocytosis; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hydrogen-Ion Concentration; Liver; Melanoma, Experimental; Mice; Microscopy, Confocal; Pinocytosis; Polyamines; Polyethyleneimine; Receptors, Cell Surface; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Wortmannin | 2007 |
In-vitro cytotoxic and genotoxic effects of arsenic trioxide on human leukemia (HL-60) cells using the MTT and alkaline single cell gel electrophoresis (Comet) assays.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Survival; Coloring Agents; Comet Assay; HL-60 Cells; Humans; Oxides; Silver Staining; Tetrazolium Salts; Thiazoles | 2007 |
DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Calcium Channel Blockers; Carcinogens; Cell Line, Tumor; Cell Survival; Cyclosporins; DNA Adducts; DNA Damage; Drug Synergism; Female; Humans; Probenecid; Renal Agents; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53; Verapamil | 2007 |
Induction of apoptosis in K562 cells by jolkinolide B.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Bromodeoxyuridine; Cell Cycle; Cell Survival; Chromatin; Colorimetry; Diterpenes; DNA; DNA Fragmentation; Electrophoresis, Agar Gel; G1 Phase; Humans; K562 Cells; Kinetics; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Tetrazolium Salts; Thiazoles | 2006 |
Cytotoxic effects of leaf, stem and root extracts of Nerium oleander on leukemia cell lines and role of the p-glycoprotein in this effect.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardenolides; Cell Line, Tumor; Dose-Response Relationship, Drug; HL-60 Cells; Humans; K562 Cells; Leukemia; Nerium; Phytotherapy; Plant Extracts; Plant Leaves; Plant Roots; Plant Stems; Tetrazolium Salts; Thiazoles | 2006 |
Inhibition of transferrin iron release increases in vitro drug carrier efficacy.
Topics: Algorithms; Antineoplastic Agents; Area Under Curve; Carbonates; Diphtheria Toxin; Drug Carriers; Drug Delivery Systems; HeLa Cells; Humans; Iron; Ligands; Models, Statistical; Oxalates; Tetrazolium Salts; Thiazoles; Transferrin | 2007 |
Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier.
Topics: Animals; Apolipoprotein A-I; Astrocytes; Blood-Brain Barrier; Blotting, Western; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Coculture Techniques; Endothelial Cells; Fluorescent Antibody Technique; Humans; Lipoproteins, HDL; Nanoparticles; Oligonucleotides; Particle Size; Protamines; Spectrometry, Mass, Electrospray Ionization; Swine; Tetrazolium Salts; Thiazoles | 2007 |
Pro-inflammatory conditions promote neuronal damage mediated by Amyloid Precursor Protein and decrease its phagocytosis and degradation by microglial cells in culture.
Topics: Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Astrocytes; Biotin; Cells, Cultured; Hippocampus; Horseradish Peroxidase; Immunohistochemistry; Inflammation; Microglia; Neurons; Phagocytosis; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Streptavidin; Tetrazolium Salts; Thiazoles | 2007 |
Inhibition by epigallocatechin gallate of CoCl2-induced apoptosis in rat PC12 cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Catechin; Cell Differentiation; Cobalt; DNA Fragmentation; Electrophoresis, Agar Gel; Flow Cytometry; Genes, bcl-2; Hypoxia-Ischemia, Brain; Membrane Potentials; Mitochondrial Membranes; Neuroprotective Agents; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Alkaloids from Prosopis juliflora leaves induce glial activation, cytotoxicity and stimulate NO production.
Topics: Alkaloids; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Blotting, Western; CD11b Antigen; Chemical Fractionation; Immunohistochemistry; L-Lactate Dehydrogenase; Nitric Oxide; Prosopis; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2007 |
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol.
Topics: Animals; Azacitidine; Base Sequence; Calcitriol; Decitabine; DNA Methylation; Endothelial Cells; Epigenesis, Genetic; Gene Silencing; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Calcitriol; Signal Transduction; Steroid Hydroxylases; Tetrazolium Salts; Thiazoles; Vitamin D3 24-Hydroxylase | 2007 |
Beta-amyloid increases somatostatin expression in cultured cortical neurons.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Necrosis; Neurons; Peptide Fragments; Radioimmunoassay; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Diterpenes; DNA Fragmentation; Epoxy Compounds; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HT29 Cells; Humans; Immunoblotting; Indoles; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
Nanoparticulate vanadium oxide potentiated vanadium toxicity in human lung cells.
Topics: Blotting, Western; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Heme Oxygenase-1; Humans; Lipid Peroxidation; Metal Nanoparticles; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Vanadium Compounds | 2007 |
Determination of the antioxidant status of plasma from type 2 diabetic patients.
Topics: Antioxidants; Blood Glucose; Body Mass Index; Cholesterol; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Granulocytes; Humans; Oxidation-Reduction; Reactive Oxygen Species; Reference Values; Serum Albumin, Bovine; Tetrazolium Salts; Thiazoles; Triglycerides | 2007 |
Immunomodulatory effects of two sapogenins 1 and 2 isolated from Luffa cylindrica in Balb/C mice.
Topics: Animals; Antibody Formation; Cell Proliferation; Dose-Response Relationship, Drug; Erythrocytes; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunologic Factors; Luffa; Lymphocytes; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Sapogenins; Sheep; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Anticancer effects of gallic acid isolated from Indonesian herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Cell Line, Tumor; DNA Fragmentation; Flow Cytometry; Gallic Acid; Gene Expression Regulation, Neoplastic; Humans; Models, Chemical; Plant Extracts; Plants; Tetrazolium Salts; Thiazoles | 2007 |
In vitro photodynamic therapy of childhood rhabdomyosarcoma.
Topics: Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Child; DNA Fragmentation; Fibroblasts; Flow Cytometry; Humans; Ki-67 Antigen; Mice; Perylene; Photochemotherapy; Rhabdomyosarcoma; Tetrazolium Salts; Thiazoles | 2007 |
Biodegradable magnesium-hydroxyapatite metal matrix composites.
Topics: Alloys; Animals; Biocompatible Materials; Biodegradation, Environmental; Calcium Carbonate; Cell Adhesion; Cell Line; Durapatite; Electrochemistry; Humans; Magnesium; Metals; Mice; Osteoblasts; Synchrotrons; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2007 |
Release of intracellular Zn(2+) in cultured neurons after brief exposure to low concentrations of exogenous nitric oxide.
Topics: Animals; Cells, Cultured; Hemoglobins; Metallothionein; Microscopy, Fluorescence; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction; Spermine; Tetrazolium Salts; Thiazoles; Time Factors; Zinc | 2007 |
Antidepressant like effects of piperine in chronic mild stress treated mice and its possible mechanisms.
Topics: Alkaloids; Animals; Antidepressive Agents; Benzodioxoles; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cells, Cultured; Chronic Disease; Corticosterone; Depression; Hippocampus; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Mice; Neurons; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Stress, Psychological; Tetrazolium Salts; Thiazoles; Weight Gain | 2007 |
Anti-tumor effects of Rubratoxin B on cell toxicity, inhibition of cell proliferation, cytotoxic activity and matrix metalloproteinase-2,9.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Matrix Metalloproteinase Inhibitors; Mycelium; Mycotoxins; Penicillium; Soil Microbiology; Tetrazolium Salts; Thiazoles | 2007 |
Effects of dust storm PM2.5 on cell proliferation and cell cycle in human lung fibroblasts.
Topics: Cell Count; Cell Cycle; Cell Line; Cell Proliferation; Cells, Cultured; Dust; Fibroblasts; Flow Cytometry; Humans; Lung; Particulate Matter; Tetrazolium Salts; Thiazoles | 2007 |
Ginkgo biloba extract reduces endothelial progenitor-cell senescence through augmentation of telomerase activity.
Topics: beta-Galactosidase; Blotting, Western; Cellular Senescence; Clone Cells; Endothelial Cells; Ginkgo biloba; Humans; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Plant Extracts; Stem Cells; Telomerase; Tetrazolium Salts; Thiazoles | 2007 |
In vitro gene expression data supporting a DNA non-reactive genotoxic mechanism for ochratoxin A.
Topics: Apoptosis; Cell Line; Comet Assay; DNA; DNA Damage; Electron Transport; Fluorescent Dyes; Gene Expression; Humans; Kidney; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Mutagens; Ochratoxins; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; RNA; Tetrazolium Salts; Thiazoles | 2007 |
Ultrafine biocompatible chitosan nanoparticles encapsulating multi-coloured quantum dots for bioapplications.
Topics: Animals; Biosensing Techniques; Cells, Cultured; Chitosan; Materials Testing; Metal Nanoparticles; Myoblasts; Particle Size; Quantum Dots; Tetrazolium Salts; Thiazoles | 2007 |
Short-chain 3-ketoceramides, strong apoptosis inducers against human leukemia HL-60 cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Ceramides; Cytochromes c; Cytosol; DNA Fragmentation; Enzyme Activation; Glutathione; HL-60 Cells; Humans; Immunoblotting; Indicators and Reagents; Mitochondria; Reactive Oxygen Species; Signal Transduction; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
Topics: Apoptosis Regulatory Proteins; Binding Sites; Cell Line; Cell Survival; Crystallography, X-Ray; Heterocyclic Compounds; Humans; Hydrogen Bonding; Intracellular Signaling Peptides and Proteins; Ligands; Magnetic Resonance Spectroscopy; Mitochondrial Proteins; Models, Molecular; Molecular Conformation; Molecular Mimicry; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; X-Linked Inhibitor of Apoptosis Protein | 2007 |
Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Biguanides; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Complex I; Electron Transport Complex II; Enzyme Activation; Glucose; Hypoglycemic Agents; Insulin-Secreting Cells; Metformin; Mice; Mitochondria; Multienzyme Complexes; NADP; Oxidation-Reduction; Phenformin; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Succinates; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Rap1/B-Raf signaling is activated in neuroendocrine tumors of the digestive tract and Raf kinase inhibition constitutes a putative therapeutic target.
Topics: Benzenesulfonates; Digestive System Neoplasms; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Neuroendocrine Tumors; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins B-raf; Pyridines; raf Kinases; rap1 GTP-Binding Proteins; Signal Transduction; Sorafenib; Tetrazolium Salts; Thiazoles | 2007 |
Naturally occurring cobalamins have antimalarial activity.
Topics: Animals; Antimalarials; Hemeproteins; Humans; Malaria, Falciparum; Plasmodium falciparum; Tetrazolium Salts; Thiazoles; Vitamin B 12 | 2007 |
Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Antioxidants; Azoles; Benzhydryl Compounds; Cells, Cultured; Deoxyguanosine; Gene Expression; Glutathione; HSP72 Heat-Shock Proteins; Hydrogen Peroxide; In Vitro Techniques; Isoindoles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Organoselenium Compounds; Oxidative Stress; Pyrrolidinones; Rabbits; Rats; Rats, Sprague-Dawley; Selenium; Tetrazolium Salts; Thiazoles | 2006 |
Ostreolysin affects rat aorta ring tension and endothelial cell viability in vitro.
Topics: Animals; Aorta; Cell Line; Cell Survival; Cricetinae; Cricetulus; Endothelial Cells; Fungal Proteins; Hemolysin Proteins; Humans; Muscle Tonus; Pleurotus; Rats; Tetrazolium Salts; Thiazoles | 2007 |
The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
Topics: Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Flow Cytometry; G1 Phase; G2 Phase; Humans; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection; Transketolase | 2007 |
Antitumor properties of diastereomeric and geometric analogs of vitamin D3.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Calcitriol; Calcium; Carcinoma, Lewis Lung; CD11b Antigen; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Coloring Agents; Female; Fibroblasts; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pancreatic Neoplasms; Prostatic Neoplasms; Rhodamines; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2007 |
Amygdalin suppresses lipopolysaccharide-induced expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells.
Topics: Amygdalin; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Gene Expression Regulation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Panax ginseng increases hypoxia-induced down-regulated cellular response related genes in human neuroblastoma cells, SK-N-MC.
Topics: Analysis of Variance; Cell Cycle Proteins; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Profiling; Humans; Kinesins; Neoplasm Proteins; Neuroblastoma; Oligonucleotide Array Sequence Analysis; Panax; Phosphoproteins; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Syntenins; Tetrazolium Salts; Thiazoles | 2007 |
Neuroprotective effect by Dammishimgyu-herbal acupuncture against H(2)O(2)-induced apoptosis in human neuroblastoma, SH-SY5Y cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Drug Interactions; Gene Expression Regulation; Herbal Medicine; Humans; Hydrogen Peroxide; Indoles; Neuroblastoma; Neuroprotective Agents; Nitrites; Tetrazolium Salts; Thiazoles | 2007 |
Induction of reactive oxygen species and apoptosis in BEAS-2B cells by mercuric chloride.
Topics: Apoptosis; Biomarkers; Caspase 3; Cell Line, Tumor; Chromatin; Enzyme Activation; Epithelial Cells; Fluorescent Dyes; Gene Expression; Glutathione; Humans; Indoles; Mercuric Chloride; Microscopy, Fluorescence; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
Effect of colloidal silver against the cytotoxicity of hydrogen peroxide and naphthazarin on primary cultured cortical astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Hydrogen Peroxide; L-Lactate Dehydrogenase; Naphthoquinones; Oxidants; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Silver Compounds; Tetrazolium Salts; Thiazoles | 2007 |
Inhibitory effect of Yangkyuk-Sanhwa-Tang on inflammatory cytokine production in peripheral blood mononuclear cells from the cerebral infarction patients.
Topics: Cells, Cultured; Cerebral Infarction; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Tetrazolium Salts; Thiazoles | 2007 |
Morphological study on apoptosis Hela cells induced by soyasaponins.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Fragmentation; DNA, Neoplasm; Glycine max; HeLa Cells; Humans; In Situ Nick-End Labeling; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Saponins; Tetrazolium Salts; Thiazoles | 2007 |
Effect of mineral trioxide aggregate cements on transforming growth factor beta1 and bone morphogenetic protein production by human fibroblasts in vitro.
Topics: Aluminum Compounds; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Calcium Compounds; Cell Survival; Cells, Cultured; Coloring Agents; Drug Combinations; Fibroblasts; Gingiva; Humans; Materials Testing; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2007 |
Cytotoxicity of DP-bioglass paste used for treatment of dentin hypersensitivity.
Topics: Adolescent; Adult; Biocompatible Materials; Cell Survival; Cells, Cultured; Coloring Agents; Dental Cements; Dental Pulp; Dentin; Dentin Sensitivity; Humans; Materials Testing; Methylmethacrylates; Tetrazolium Salts; Thiazoles; Zinc Oxide-Eugenol Cement | 2007 |
The effects of nickel and chromium on human keratinocytes: differences in viability, cell associated metal and IL-1alpha release.
Topics: Algorithms; Benzimidazoles; Cell Separation; Cell Survival; Cells, Cultured; Chromium; Cytokines; Data Interpretation, Statistical; Dermatitis, Contact; Enzyme-Linked Immunosorbent Assay; Fluorescent Dyes; Humans; Interleukin-1alpha; Interleukin-8; Keratinocytes; Mitochondria; Nickel; Propidium; Skin Tests; Tetrazolium Salts; Thiazoles | 2007 |
Precision-cut tissue chips as an in vitro toxicology system.
Topics: Alkylating Agents; Animals; Bridged Bicyclo Compounds; Cell Survival; Dithionitrobenzoic Acid; Fluoresceins; Fluorescent Dyes; Fura-2; Iodoacetamide; Mice; Mice, Inbred C57BL; Microtomy; Potassium; Sulfhydryl Reagents; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques; Toxicology | 2007 |
Impact of 3,4-dideoxyglucosone-3-ene (3,4-DGE) on cytotoxicity of acidic heat-sterilized peritoneal dialysis fluid.
Topics: Dialysis Solutions; Hemodialysis Solutions; Humans; Peritoneal Dialysis; Peritoneum; Pyrones; Sterilization; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2007 |
First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Antineoplastic Agents; Blotting, Western; Catalysis; Cell Line, Tumor; Computational Biology; Databases, Factual; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Models, Molecular; Neoplasm Proteins; Prostatic Neoplasms; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Organotypic human oral tissue models for toxicological studies.
Topics: Cytokines; Electric Impedance; Epithelial Cells; Gingiva; Humans; Immunohistochemistry; Mouth; Mouth Mucosa; Mouthwashes; Quality Control; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques; Toothpastes | 2007 |
In vitro and in vivo toxicity of type 2 ribosome-inactivating proteins lanceolin and stenodactylin on glial and neuronal cells.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebellum; Choline O-Acetyltransferase; Lectins; Leucine; Male; N-Glycosyl Hydrolases; Nerve Tissue Proteins; Neuroglia; Neurons; Passifloraceae; Plant Lectins; Rats; Rats, Wistar; Ribosome Inactivating Proteins, Type 2; Tetrazolium Salts; Thiazoles | 2007 |
Inhibition of invasion and induction of apoptosis by selenium in human malignant brain tumour cells in vitro.
Topics: Adolescent; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Neoplasm Invasiveness; RNA; Selenium; Tetrazolium Salts; Thiazoles | 2007 |
Comparison of results of the CellTiter Blue, the tetrazolium (3-[4,5-dimethylthioazol-2-yl]-2,5-diphenyl tetrazolium bromide), and the lactate dehydrogenase assay applied in brain cells after exposure to advanced glycation endproducts.
Topics: Animals; Brain; Cell Count; Cell Line; Cell Survival; Coloring Agents; Glycation End Products, Advanced; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Mice; Proteins; Reproducibility of Results; Serum Albumin; Tetrazolium Salts; Thiazoles | 2007 |
On the cytotoxicity and status of oxidative stress of two novel synthesized tri-aza macrocyclic diamides as studied in the V79 cell lines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catalase; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Deoxyguanosine; Diamide; DNA Damage; Glutathione Peroxidase; Lipid Peroxidation; Macrocyclic Compounds; Malondialdehyde; Oxidative Stress; Proteins; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tyrosine; Vitamin E | 2007 |
The anti-cancer effect of COX-2 inhibitors on gastric cancer cells.
Topics: Adenocarcinoma; Apoptosis; Celecoxib; Cell Cycle; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Microscopy, Fluorescence; Pyrazoles; Stomach Neoplasms; Sulfonamides; Tetrazolium Salts; Thiazoles | 2007 |
Deficient peroxide detoxification underlies the susceptibility of oligodendrocyte progenitors to dopamine toxicity.
Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Dopamine; Glutathione; Heme Oxygenase-1; Iron; Isoindoles; L-Lactate Dehydrogenase; Metalloporphyrins; Oligodendroglia; Organoselenium Compounds; Oxidants; Peroxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stem Cells; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 2007 |
Neuroprotection from secondary injury by polyethylene glycol requires its internalization.
Topics: Animals; Cell Membrane; Cytosol; Lipid Peroxidation; Microscopy, Fluorescence; Neurons; Neuroprotective Agents; PC12 Cells; Polyethylene Glycols; Rats; Tetrazolium Salts; Thiazoles | 2007 |
Prion protein aggregation and neurotoxicity in cortical neurons.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Cerebral Cortex; L-Lactate Dehydrogenase; Lipid Peroxidation; Neurons; Oxidative Stress; Prions; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Differential Signaling and Hypertrophic Responses in Cyclically Stretched vs Endothelin-1 Stimulated Neonatal Rat Cardiomyocytes.
Topics: Actins; Animals; Animals, Newborn; DNA; Endothelin-1; Fluorescent Dyes; Hypertrophy; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Microscopy, Confocal; Myocytes, Cardiac; Protein Transport; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
Overexpression of integrin beta1 inhibits proliferation of hepatocellular carcinoma cell SMMC-7721 through preventing Skp2-dependent degradation of p27 via PI3K pathway.
Topics: Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Gene Expression Regulation; Humans; Integrin beta1; Liver Neoplasms; Models, Biological; Phosphatidylinositol 3-Kinases; Proteasome Inhibitors; S-Phase Kinase-Associated Proteins; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2007 |
Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-gamma expression.
Topics: Bidens; Flavonoids; Glucosides; Humans; Interferon Inducers; Interferon-gamma; Jurkat Cells; NF-kappa B; Plant Extracts; Promoter Regions, Genetic; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2007 |
Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells.
Topics: Acetylcholinesterase; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Blotting, Western; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neuroprotective Agents; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Cytotoxicity evaluation of anionic nanoliposomes and nanolipoplexes prepared by the heating method without employing volatile solvents and detergents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coloring Agents; Detergents; DNA; Drug Carriers; Drug Screening Assays, Antitumor; Humans; Liposomes; Neutral Red; Particle Size; Plasmids; Solvents; Tetrazolium Salts; Thiazoles | 2007 |
Prolonged cytotoxic effect of aqueous extracts from dried viscum album on bladder cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Plant Extracts; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms; Viscum | 2007 |
Use of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide for rapid detection of methicillin-resistant Staphylococcus aureus by resonance light scattering.
Topics: Colony Count, Microbial; Flavonoids; Light; Methicillin Resistance; Scattering, Radiation; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2007 |
Free radical generation during the activation of hemolymph prepared from the homopteran Dactylopius coccus.
Topics: Animals; Carmine; Hemiptera; Hemolymph; Micrococcus luteus; Monophenol Monooxygenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidation-Reduction; Serratia; Superoxide Dismutase; Superoxides; Temperature; Tetrazolium Salts; Thiazoles; Toxicity Tests; Zymosan | 2007 |
A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type.
Topics: Alkenes; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dactinomycin; Diploidy; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Lymphoma, T-Cell; Mice; Necrosis; Prodigiosin; Pyrroles; Rats; Sarcoma 180; Staurosporine; Tetrazolium Salts; Thiazoles | 2008 |
Pharmacodynamic characterization of gemcitabine cytotoxicity in an in vitro cell culture bioreactor system.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Bioreactors; Cell Cycle; Cell Death; Cell Line, Tumor; Deoxycytidine; DNA, Neoplasm; Flow Cytometry; Gemcitabine; Humans; In Situ Nick-End Labeling; Tetrazolium Salts; Thiazoles | 2008 |
Diminished feedback regulation of proteasome expression and resistance to proteasome inhibitors in breast cancer cells.
Topics: Apoptosis; Boronic Acids; Bortezomib; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Feedback, Physiological; Humans; Leupeptins; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Temperature; Tetrazolium Salts; Thiazoles | 2008 |
Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid.
Topics: Animals; Blotting, Western; Bucladesine; Caproates; Caprylates; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Heptanoic Acids; MAP Kinase Kinase 4; Nerve Growth Factors; Neurites; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Rats; Tetrazolium Salts; Thiazoles | 2007 |
The inhibitory effects of nanosize delivery system for antisense oligonucleotide of hTERT on EC9706 cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Delivery Systems; Humans; Nanoparticles; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-myc; RNA, Messenger; Sp1 Transcription Factor; Telomerase; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
NBS1, the Nijmegen breakage syndrome gene product, regulates neuronal proliferation and differentiation.
Topics: Animals; Blotting, Western; Bromodeoxyuridine; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Proliferation; Cerebral Cortex; Cloning, Molecular; Culture Media, Serum-Free; Gamma Rays; Humans; Immunohistochemistry; Immunoprecipitation; Mutation; Nerve Growth Factor; Neurites; Neurons; Nijmegen Breakage Syndrome; Nuclear Proteins; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Proto-Oncogene Proteins c-akt; Rats; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2007 |
Effect of FLT3 inhibition on normal hematopoietic progenitor cells.
Topics: Antigens, CD34; Carbazoles; Dose-Response Relationship, Drug; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; Furans; Hematopoietic Stem Cells; Humans; Immunophenotyping; Indoles; Inhibitory Concentration 50; Ligands; Models, Biological; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
Induction of apoptosis by ginger in HEp-2 cell line is mediated by reactive oxygen species.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gas Chromatography-Mass Spectrometry; Humans; Liver Neoplasms; Plant Extracts; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Zingiber officinale | 2007 |
Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Drug Resistance, Multiple, Bacterial; Female; Isoniazid; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyridines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Thiourea; Tuberculosis; Vero Cells | 2007 |
Psoralea corylifolia L. inhibits mitochondrial complex I and proteasome activities in SH-SY5Y cells.
Topics: Animals; Brain; Cell Line, Tumor; Humans; Medicine, Chinese Traditional; Mice; Mitochondria; Models, Biological; NADH Dehydrogenase; Oxidative Stress; Plants, Medicinal; Proteasome Endopeptidase Complex; Psoralea; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action.
Topics: Amino Acid Sequence; Amino Acids; Animals; Bacteria; Cell Membrane; Circular Dichroism; Erythrocytes; HeLa Cells; Humans; Leucine Zippers; Melitten; Molecular Sequence Data; Peptoids; Protein Engineering; Protein Structure, Secondary; Tetrazolium Salts; Thiazoles | 2007 |
Manganese induces oxidative impairment in cultured rat astrocytes.
Topics: Adenosine Triphosphate; Amino Acid Transport System ASC; Amino Acid Transport Systems, Neutral; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Extracellular Space; F2-Isoprostanes; Glutamine; L-Lactate Dehydrogenase; Manganese Poisoning; Membrane Potentials; Minor Histocompatibility Antigens; Mitochondrial Membranes; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Decreased level of mitochondrial RNA by glutamate in cultured cortical neurons.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Expression; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Mice; NADH Dehydrogenase; Neurons; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Mitochondrial; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.
Topics: Blotting, Western; Cell Line; Cell Survival; DNA Primers; Enzyme Inhibitors; Epidermal Cells; Epidermis; Humans; Magnetic Resonance Spectroscopy; Melanins; Melanocytes; Monophenol Monooxygenase; Plant Extracts; Plants, Medicinal; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Synthesis of isomeric, oxathiolone fused chalcones, and comparison of their activity toward various microorganisms and human cancer cells line.
Topics: Anti-Infective Agents; Antineoplastic Agents; Antitubercular Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Chalcones; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isomerism; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Tetrazolium Salts; Thiazoles | 2007 |
Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase.
Topics: Analysis of Variance; Cell Line; Culture Media, Conditioned; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Insecticides; Monocytes; Neuroblastoma; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Rotenone; Tetrazolium Salts; Thiazoles; Up-Regulation | 2007 |
Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering.
Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Biomimetics; Bone and Bones; Cell Differentiation; Cell Proliferation; Durapatite; Microscopy, Electron, Scanning; Nanostructures; Nylons; Osteogenesis; Rabbits; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2007 |
Transepithelial transport of fusariotoxin nivalenol: mediation of secretion by ABC transporters.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Biological Transport, Active; Caco-2 Cells; Cell Line; Chromatography, Gas; Electrochemistry; Epithelium; Humans; Immunohistochemistry; L-Lactate Dehydrogenase; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mycotoxins; Propionates; Quinolines; Temperature; Tetrazolium Salts; Thiazoles; Trichothecenes | 2007 |
Increased resistance of tumor cells to daunorubicin after transfection of cDNAs coding for anthracycline inactivating enzymes.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Antibiotics, Antineoplastic; Cell Line, Tumor; Cloning, Molecular; Daunorubicin; DNA, Complementary; Drug Resistance; Humans; Inhibitory Concentration 50; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
Bcl-XL small interfering RNA sensitizes cisplatin-resistant human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Lung Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
Optimization of microencapsulated recombinant CHO cell growth, endostatin production, and stability of microcapsule in vivo.
Topics: Alginates; Algorithms; Animals; Capsules; Cell Division; CHO Cells; Cricetinae; Cricetulus; Drug Compounding; Endostatins; Genetic Engineering; Male; Mice; Particle Size; Peritoneal Cavity; Polylysine; Recombination, Genetic; Tetrazolium Salts; Thiazoles | 2008 |
Verification of cell irradiation dose deposition using a radiochromic film.
Topics: Calibration; Coloring Agents; Electrons; Film Dosimetry; Humans; Particle Accelerators; Photons; Radiation Dosage; Radiometry; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; X-Ray Film | 2007 |
A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Humans; Immunoprecipitation; Indoles; Lung Neoplasms; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis and characterization of deoxynivalenol glucuronide: its comparative immunotoxicity with deoxynivalenol.
Topics: Animals; Cell Count; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Glucuronidase; Glucuronides; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Rats; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Trichothecenes; Trypan Blue | 2007 |
Emodin suppresses interleukin-1beta induced mesangial cells proliferation and extracellular matrix production via inhibiting P38 MAPK.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Emodin; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Flow Cytometry; Interleukin-1beta; Male; Mesangial Cells; p38 Mitogen-Activated Protein Kinases; Polymerase Chain Reaction; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2007 |
A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ergosterol; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Plant Extracts; Plants, Medicinal; Protein Processing, Post-Translational; Proteins; S-Phase Kinase-Associated Proteins; Tetrazolium Salts; Thiazoles | 2007 |
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.
Topics: Animals; Cell Line, Tumor; Databases, Genetic; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorescent Antibody Technique; Glucose Transporter Type 1; Green Fluorescent Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Metabolism; Paraffin Embedding; Tetrazolium Salts; Thiazoles; Tissue Fixation; Xenograft Model Antitumor Assays | 2008 |
Cryopreservation of composite tissue flaps: experimental studies in the rat.
Topics: Animals; Cell Survival; Cryopreservation; Endothelium; Equipment Design; Indicators and Reagents; Male; Rats; Rats, Inbred Lew; Surgical Flaps; Tetrazolium Salts; Thiazoles; Tissue and Organ Harvesting; Transplantation, Homologous | 2007 |
Biomedical evaluation of polyvinyl alcohol-gelatin esterified hydrogel for wound dressing.
Topics: Animals; Bandages; Biocompatible Materials; Cell Line; Cell Survival; Esterification; Gelatin; Goats; Hydrogels; Materials Testing; Mice; Polyvinyl Alcohol; Tetrazolium Salts; Thiazoles | 2007 |
Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Creatine; Creatine Kinase; Energy Metabolism; Female; gamma-Aminobutyric Acid; Immunohistochemistry; Mitogen-Activated Protein Kinase 1; Neurons; Nitro Compounds; Pregnancy; Propionates; Rats; Spinal Cord; Stem Cells; Tetrazolium Salts; Thiazoles; Tubulin | 2007 |
The rapid decline of MTT reduction is not a marker of death signaling in ouabain-treated cells.
Topics: Animals; Apoptosis; Biomarkers; Cardiac Glycosides; Caspase 3; Cell Adhesion; Cell Death; Cells, Cultured; Dogs; Enzyme Activation; Hydrogen-Ion Concentration; Ouabain; Oxidation-Reduction; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2006 |
Liposomes for drug delivery to the lungs by nebulization.
Topics: Adhesives; Adsorption; Aerosols; Antibiotics, Antitubercular; Calorimetry, Differential Scanning; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Cholesterol; Drug Compounding; Drug Delivery Systems; Excipients; Freeze Drying; Humans; Liposomes; Lung; Mucous Membrane; Nebulizers and Vaporizers; Particle Size; Pulmonary Alveoli; Rifampin; Surface Properties; Tetrazolium Salts; Thermodynamics; Thiazoles | 2007 |
N,N,N-Trimethylchitosan chloride as a gene vector: synthesis and application.
Topics: Cell Line; Chitosan; DNA; Genetic Vectors; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Particle Size; Tetrazolium Salts; Thiazoles; Toxicity Tests; Transfection | 2007 |
Two new bisorbicillinoids isolated from a deep-sea fungus, Phialocephala sp. FL30r.
Topics: Antibiotics, Antineoplastic; Ascomycota; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Diterpenes; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2007 |
4849F, a new metabolite produced by the Streptomyces sp. 4849 as an inhibitor of IL-4 receptor.
Topics: Chemical Phenomena; Chemistry, Physical; Gram-Positive Bacteria; Interleukin-4; Ligands; Magnetic Resonance Spectroscopy; Pyridazines; Receptors, Interleukin-4; Spectrophotometry, Ultraviolet; Streptomyces; Tetrazolium Salts; Thiazoles | 2007 |
Activation of Src by c-Met overexpression mediates metastatic properties of colorectal carcinoma cells.
Topics: Autoradiography; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Immunohistochemistry; Immunoprecipitation; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphorylation; Prognosis; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Vascular Endothelial Growth Factor A | 2007 |
Anti-angiogenic effect of Biophytum sensitivum is exerted through its cytokine modulation activity and inhibitory activity against VEGF mRNA expression, endothelial cell migration and capillary tube formation.
Topics: Angiogenesis Inhibitors; Animals; Capillaries; Cell Line, Tumor; Cell Movement; Cell Survival; Cytokines; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Melanoma, Experimental; Microtubules; Plants; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A | 2007 |
Poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Coumarins; Drug Compounding; Fluorescent Dyes; Glioma; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pressure; Tetrazolium Salts; Thiazoles | 2007 |
Antiviral activity of carbohydrate-binding agents against Nidovirales in cell culture.
Topics: Animals; Anthracyclines; Antiviral Agents; Bacterial Proteins; Carrier Proteins; Cats; Cell Line; Chlorocebus aethiops; Colorimetry; Female; Galanthus; Immunohistochemistry; Liliaceae; Luciferases; Magnoliopsida; Mice; Microbial Sensitivity Tests; Nidovirales; Plant Lectins; RNA Virus Infections; Swine; Tetrazolium Salts; Thiazoles; Urtica dioica | 2007 |
The effect of the polyadenylation inhibitor cordycepin on human Molt-4 and Daudi leukaemia and lymphoma cell lines.
Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxyadenosines; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Indoles; Leukemia; Lymphoma; Membrane Potentials; Mitochondria; Necrosis; Polynucleotide Adenylyltransferase; Tetrazolium Salts; Thiazoles | 2008 |
Epigallocatechin gallate, an active ingredient from green tea, attenuates damaging influences to the retina caused by ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Catechin; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Drug Interactions; Electroretinography; Eye Proteins; Glial Fibrillary Acidic Protein; Hydrogen Peroxide; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Retinal Diseases; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thy-1 Antigens | 2007 |
Clastogenic and cytotoxic effects of lipid peroxidation products generated in culinary oils submitted to thermal stress.
Topics: Chromatids; Chromosome Aberrations; Chromosome Breakage; Cytotoxins; Endothelial Cells; Hot Temperature; Humans; Lipid Peroxidation; Lymphocytes; Mutagens; Oxidative Stress; Plant Oils; Sunflower Oil; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances | 2007 |
Inhibition of caspases but not of calpains temporarily protect against C2-ceramide-induced death of CAD cells.
Topics: Analysis of Variance; Animals; Calpain; Caspases; Cell Death; Cell Line; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Mice; Neurons; Neuroprotective Agents; Sphingosine; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Dietary influence on pancreatic cancer growth by catechin and inositol hexaphosphate.
Topics: Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Necrosis; Pancreatic Neoplasms; Phytic Acid; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
Antioxidative and anticancer activity of extracts of cherry (Prunus serrulata var. spontanea) blossoms.
Topics: Anticarcinogenic Agents; Antioxidants; Biphenyl Compounds; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; HT29 Cells; Humans; Hydrazines; Leukocytes; Phenols; Picrates; Plant Extracts; Prunus; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Water soluble RNA based antagonist of AMPA receptors.
Topics: Animals; Aptamers, Nucleotide; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fluorescence Resonance Energy Transfer; Glucose; Glutamic Acid; Hypoxia; Membrane Potentials; Neocortex; Neurons; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Rats; Receptors, AMPA; SELEX Aptamer Technique; Tetrazolium Salts; Thiazoles | 2007 |
Purified and sterilized magnetosomes from Magnetospirillum gryphiswaldense MSR-1 were not toxic to mouse fibroblasts in vitro.
Topics: Animals; Cells, Cultured; Cytoplasmic Granules; Fibroblasts; Magnetics; Magnetospirillum; Mice; Microscopy, Electron, Transmission; Nanoparticles; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2007 |
Identification of genes differentially expressed in SH-SY5Y neuroblastoma cells exposed to the prion peptide 106-126.
Topics: Cell Death; Cell Line, Tumor; Down-Regulation; Gene Expression; Humans; Microscopy, Fluorescence; Neuroblastoma; Neuroglia; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Prions; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Transcription, Genetic | 2007 |
Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Mice; Mice, Inbred C57BL; Micelles; Nanoparticles; Neoplasms; Phosphatidylethanolamines; Phospholipids; Polyethylene Glycols; Tetrazolium Salts; Thiazoles | 2007 |
Surface tailoring of poly(ethylene terephthalate) via ligand-tethered comb-like PEG to enhance endothelialization.
Topics: Aldehydes; Cell Adhesion; Cell Proliferation; Cell Survival; Endothelial Cells; Endothelium; Humans; Ligands; Lysine; Platelet Adhesiveness; Polyethylene Glycols; Polyethylene Terephthalates; Surface Properties; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2008 |
PAN-811 provides neuroprotection against glutamate toxicity by suppressing activation of JNK and p38 MAPK.
Topics: Animals; Anthracenes; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Genes, bcl-2; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Thiosemicarbazones | 2007 |
Activation of phosphoinositide-3 kinase/Akt pathway by FeSO4 in rat cerebral cortex synaptic endings.
Topics: Animals; Cerebral Cortex; Chromones; Enzyme Activation; Enzyme Inhibitors; Ferrous Compounds; Glutamic Acid; Immunoprecipitation; Morpholines; Phosphatidylinositol 3-Kinases; Presynaptic Terminals; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Photodynamic therapy with a new photosensitizing agent.
Topics: Cell Nucleus; Coloring Agents; Humans; Indoles; Isoindoles; Low-Level Light Therapy; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Tetrazolium Salts; Thiazoles; Zinc Compounds | 2007 |
Antistaphylococcal activities of CG400549, a new bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor.
Topics: Anti-Bacterial Agents; Benzamidines; Cell Line, Tumor; Cell Survival; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Guanidines; Humans; Microbial Sensitivity Tests; Neutral Red; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Inhibitory effect of trimidox on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages.
Topics: Actins; Animals; Benzamidines; Blotting, Western; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Tetrazolium Salts; Thiazoles | 2007 |
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Blotting, Western; Calcium; Cell Line, Tumor; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2008 |
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Line, Tumor; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lung Neoplasms; Medicine, Chinese Traditional; Mutation; Sesquiterpenes; Taxoids; Tetrazolium Salts; Thiazoles | 2007 |
Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
Topics: Angiogenesis Inducing Agents; Animals; Cell Line, Tumor; Cell Proliferation; Corneal Surgery, Laser; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Interleukin-8; Mice; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Tetrazolium Salts; Thiazoles; Time Factors; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2008 |
Protective effect of erythropoietin against 1-methyl-4-phenylpyridinium-induced neurodegenaration in PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Erythropoietin; Flow Cytometry; Herbicides; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial; Neuroprotective Agents; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Yulda-Hanso-Tang attenuates the endotoxin-induced inflammatory cytokine production in peripheral blood mononuclear cells.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Inhibition of tumor metastasis by a growth factor receptor bound protein 2 Src homology 2 domain-binding antagonist.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; GRB2 Adaptor Protein; Humans; Mice; Mice, SCID; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; Protein Binding; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles | 2007 |
Ethanol extract of fermented soybean, Chungkookjang, inhibits the apoptosis of mouse spleen, and thymus cells.
Topics: Animals; Annexin A5; Apoptosis; Cell Survival; Cells, Cultured; DNA Fragmentation; Electrophoresis, Capillary; Fermentation; Flow Cytometry; Glycine max; Immunologic Factors; Isoflavones; Lymphocytes; Mice; Mice, Inbred BALB C; Plant Extracts; Propidium; Spleen; Tetrazolium Salts; Thiazoles; Thymus Gland | 2007 |
Crosslinked hyaluronan with a protein-like polymer: novel bioresorbable films for biomedical applications.
Topics: Aspartame; Calorimetry, Indirect; Cell Adhesion; Cell Survival; Coated Materials, Biocompatible; Cross-Linking Reagents; Fibroblasts; Humans; Hyaluronic Acid; Hydrogels; Hydrolysis; Nephelometry and Turbidimetry; Polyamines; Proteins; Skin; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Trypan Blue; Wound Healing | 2008 |
Preparation of fibroin/recombinant human-like collagen scaffold to promote fibroblasts compatibility.
Topics: 3T3 Cells; Animals; Biomechanical Phenomena; Cell Proliferation; Chemical Phenomena; Chemistry, Physical; Collagen; Fibroblasts; Fibroins; Humans; Materials Testing; Mice; Porosity; Recombinant Proteins; Silk; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2008 |
Hydroxyapatite-coated polyurethane for auricular cartilage replacement: an in vitro study.
Topics: Cell Adhesion; Cell Line; Cell Line, Tumor; Coated Materials, Biocompatible; DNA; Durapatite; Ear Cartilage; Fibroblasts; Gentian Violet; Humans; Implants, Experimental; Microscopy, Electron, Scanning; Polyurethanes; Prosthesis Design; Rosaniline Dyes; Tetrazolium Salts; Thiazoles; Tomography, X-Ray Computed | 2008 |
In vitro biological evaluation of beta-TCP/HDPE--A novel orthopedic composite: a survey using human osteoblast and fibroblast bone cells.
Topics: Biocompatible Materials; Bone and Bones; Calcium Phosphates; Cell Adhesion; Cell Line; Cell Proliferation; Fibroblasts; Humans; Materials Testing; Microscopy, Electron, Scanning; Osteoblasts; Polyethylene; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2008 |
In vitro activity of para-guanidinoethylcalix[4]arene against susceptible and antibiotic-resistant Gram-negative and Gram-positive bacteria.
Topics: Anti-Bacterial Agents; Benzamidines; Calixarenes; Cell Line, Tumor; Cell Survival; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Guanidines; Humans; Microbial Sensitivity Tests; Neutral Red; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Osteoblast interactions with various hydroxyapatite based biomaterials consolidated using a spark plasma sintering technique.
Topics: Alkaline Phosphatase; Biocompatible Materials; Bone Development; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Culture Media; Fetus; Genes, Reporter; Humans; Hydroxyapatites; Microscopy, Electron, Scanning; Osteoblasts; Osteocalcin; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2008 |
Fluoride-induced oxidative stress of osteoblasts and protective effects of baicalein against fluoride toxicity.
Topics: Animals; Antioxidants; Cell Proliferation; Cell Survival; Flavanones; Fluorides; Lipid Peroxidation; Mice; Mitochondria; Models, Biological; Osteoblasts; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2007 |
Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Cell Line; Cell Survival; Humans; Indans; Neurons; Neuroprotective Agents; Oxidopamine; PC12 Cells; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Rats; Sympatholytics; Tetrazolium Salts; Thiazoles | 2007 |
Cocaine exposure in vitro induces apoptosis in fetal locus coeruleus neurons through TNF-alpha-mediated induction of Bax and phosphorylated c-Jun NH(2)-terminal kinase.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Survival; Cells, Cultured; Cocaine; Culture Media; Cyclin D1; Data Interpretation, Statistical; Enzyme-Linked Immunosorbent Assay; Female; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Locus Coeruleus; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Rats; Rats, Long-Evans; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2007 |
The role of Akt-GSK-3beta signaling and synaptic strength in phencyclidine-induced neurodegeneration.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Nerve Degeneration; Oncogene Protein v-akt; Phencyclidine; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Synapses; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Hypothermia suppresses inflammation via ERK signaling pathway in stimulated microglial cells.
Topics: Animals; Animals, Newborn; Cell Count; Cell Survival; Cells, Cultured; Cold Temperature; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hypothermia; Interleukin-6; Mice; Microglia; Nitric Oxide Synthase Type II; Polysaccharides; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Study of high glucose-induced apoptosis in PC12 cells: role of bax protein.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Survival; DNA Fragmentation; DNA, Neoplasm; Glucose; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Tetrazolium Salts; Thiazoles | 2007 |
Effect of the population heterogeneity on growth behavior and its estimation.
Topics: Bacteria; Colony Count, Microbial; Escherichia coli; Flow Cytometry; Logistic Models; Microscopy, Confocal; Models, Biological; Oxidoreductases; Tetrazolium Salts; Thiazoles | 2007 |
Suppression of Bcl-xL expression by a novel tumor-specific RNA interference system inhibits proliferation and enhances radiosensitivity in prostatic carcinoma cells.
Topics: Apoptosis; bcl-X Protein; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Flow Cytometry; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Luciferases; Male; Neoplasm Transplantation; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Radiation-Sensitizing Agents; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles; Transfection; Transplantation, Heterologous; Tumor Stem Cell Assay | 2008 |
LPS-induced inflammatory cytokine production was inhibited by HyungbangJihwangTang through blockade of NF-kappaB in peripheral blood mononuclear cells.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Herbal Medicine; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Medicine, East Asian Traditional; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Induction of apoptosis of human gastric carcinoma SGC-7901 cell line by 5, 7-dihydroxy-8-nitrochrysin in vitro.
Topics: Anilides; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Line, Tumor; Cell Proliferation; Electrophoresis, Agar Gel; Flavonoids; Flow Cytometry; Humans; Nitro Compounds; PPAR gamma; Propidium; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2007 |
A rapid and accurate 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide colorimetric assay for quantification of bacteriocins with nisin as an example.
Topics: Bacteriocins; Colorimetry; Immunodiffusion; Micrococcus luteus; Nisin; Regression Analysis; Tetrazolium Salts; Thiazoles; Time Factors | 2007 |
Mast cell-derived mediators protect against oxygen-glucose deprivation-induced injury in PC12 cells and neurons.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Culture Media; Glucose; Hippocampus; Histamine; Histamine Release; Inflammation Mediators; Male; Mast Cells; Nerve Growth Factor; Neurons; PC12 Cells; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2007 |
Antioxidative and antitumor activity of derivatives of 4-beta-amino-4'-demethylepipodophyllotoxin and their structure-activity relationship.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Erythrocytes; Female; Hemolysis; Humans; Hydrogen Peroxide; Indicators and Reagents; K562 Cells; Liver; Male; Malondialdehyde; Neutrophils; Podophyllotoxin; Rats; Structure-Activity Relationship; Superoxides; Tetrazolium Salts; Thiazoles | 2007 |
Effects of oridonin on proliferation of HT29 human colon carcinoma cell lines both in vitro and in vivo in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Diterpenes; Diterpenes, Kaurane; Female; HT29 Cells; Humans; Indicators and Reagents; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles | 2007 |
In vitro anti-oxidative and anti-inflammatory effects of solvent-extracted fractions from Suaeda asparagoides.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Cell Line; Cell Proliferation; Chemokines; Chenopodiaceae; Cytokines; Enzyme Inhibitors; Free Radical Scavengers; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Phenols; Picrates; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solvents; Tetrazolium Salts; Thiazoles; Xanthine Oxidase | 2007 |
A new piperazine-2,5-dione from the marine fungus Gliocladium sp.
Topics: Amino Acids; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Gliocladium; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Conformation; Piperazines; Spectrometry, Mass, Fast Atom Bombardment; Tetrazolium Salts; Thiazoles; Vincristine | 2007 |
Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Analysis of Variance; Animals; Cation Transport Proteins; CD11b Antigen; Cell Count; Cells, Cultured; Ferric Compounds; Fluoresceins; Glial Fibrillary Acidic Protein; Iron; Iron-Regulatory Proteins; Mice; Neuroglia; Neurons; Oxidopamine; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics; Tetrazolium Salts; Thiazoles; Up-Regulation | 2007 |
Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate.
Topics: Apoptosis; Butyrates; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Humans; In Situ Nick-End Labeling; Isobutyrates; Oncogene Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2007 |
Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice.
Topics: Administration, Topical; Animals; Blotting, Western; Cells, Cultured; Collagen Type I; Dipeptidases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Image Processing, Computer-Assisted; Ketoglutaric Acids; Mice; Mice, Hairless; Procollagen; Proline; Skin; Skin Aging; Stimulation, Chemical; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2007 |
Cytotoxic germacranolide sesquiterpene from Inula cappa.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Ethanol; HeLa Cells; Humans; Inula; K562 Cells; KB Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Sesquiterpenes; Sesquiterpenes, Germacrane; Solvents; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2007 |
A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata.
Topics: Animals; Cell Survival; Dinoprostone; Flavanones; Fruit; Glycosides; Interleukin-6; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Poncirus; Prostaglandin Antagonists; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Comparison of the antivascular and cytotoxic activities of TZT-1027 (Soblidotin) with those of other anticancer agents.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Colonic Neoplasms; Dextrans; Diffusion; Endothelial Cells; Endothelium, Vascular; Female; Fluorescein-5-isothiocyanate; Humans; Indicators and Reagents; Mice; Mice, Inbred BALB C; Oligopeptides; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2007 |
Electrical stimulation enhances viability of human cutaneous fibroblasts on conductive biodegradable substrates.
Topics: Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Survival; Cells, Cultured; Electric Conductivity; Electricity; Equipment Design; Fibroblasts; Humans; Microscopy, Electron, Scanning; Mitochondria; Polymers; Skin; Tetrazolium Salts; Thiazoles | 2008 |
Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.
Topics: Aminocaproic Acid; Arginine; beta-Alanine; Biological Transport; Cell Line; Cell Survival; Culture Media; Hemolysis; Humans; Indicators and Reagents; Oligonucleotides, Antisense; Peptides; Propidium; RNA Splicing; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2007 |
In vivo and in vitro anti-inflammatory activities of alpha-linolenic acid isolated from Actinidia polygama fruits.
Topics: Acetic Acid; Actinidia; alpha-Linolenic Acid; Aminolevulinic Acid; Animals; Anti-Inflammatory Agents; Blotting, Western; Capillary Permeability; Carrageenan; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Enzyme Inhibitors; Fruit; Hexanes; Indicators and Reagents; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Solvents; Tetrazolium Salts; Thiazoles | 2007 |
Anti-inflammatory constituents isolated from Clerodendron trichotomum Tunberg Leaves (CTL) inhibits pro-inflammatory gene expression in LPS-stimulated RAW 264.7 macrophages by suppressing NF-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Clerodendrum; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Inflammation; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2007 |
Fiber density of electrospun gelatin scaffolds regulates morphogenesis of dermal-epidermal skin substitutes.
Topics: Animals; Biocompatible Materials; Dermis; Epidermis; Fibroblasts; Gelatin; Humans; Keratinocytes; Materials Testing; Microscopy, Electron, Scanning; Porosity; Regeneration; Skin, Artificial; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2008 |
22R-Hydroxycholesterol induces differentiation of human NT2 precursor (Ntera2/D1 teratocarcinoma) cells.
Topics: Bromodeoxyuridine; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cholesterol; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Humans; Hydroxycholesterols; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Neurons; ras Guanine Nucleotide Exchange Factors; Teratocarcinoma; Tetrazolium Salts; Thiazoles; Time Factors; Tritium | 2007 |
Effective treatment of leukemic cell lines with wt1 siRNA.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Genes, Wilms Tumor; Genetic Therapy; HL-60 Cells; Humans; K562 Cells; Leukemia; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2007 |
Effects of Notch-1 signalling pathway on differentiation of marrow mesenchymal stem cells into neurons in vitro.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Gene Expression; In Situ Nick-End Labeling; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Neurons; Receptor, Notch1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2007 |
The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma.
Topics: Animals; Antipsychotic Agents; Cell Survival; Cells, Cultured; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Interactions; Interferon-gamma; Isoindoles; Mice; Mice, Inbred C57BL; Microglia; Nitrites; Piperazines; Quetiapine Fumarate; Rats; Tetrazolium Salts; Thiazoles | 2008 |
Preparation of a TK/GCV administration system mediated by transferrin modified pro-cationic liposomes.
Topics: Carcinoma, Hepatocellular; Cations; Cell Division; Cell Line, Tumor; Cell Survival; Dithiothreitol; DNA; Drug Carriers; Electrochemistry; Ganciclovir; Humans; Indicators and Reagents; Liposomes; Sulfhydryl Reagents; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transferrin | 2007 |
Cytotoxicity of different types of methylated beta-cyclodextrins and ionic derivatives.
Topics: Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Indicators and Reagents; Methylation; Tetrazolium Salts; Thiazoles | 2007 |
Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B.
Topics: Antioxidants; Ascorbic Acid; Benzofurans; Benzothiazoles; Biphenyl Compounds; Cell Survival; Chelating Agents; Endothelial Cells; Ferrous Compounds; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lactates; Oxidants; Picrates; Plant Roots; Salvia; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2008 |
Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Bile Acids and Salts; Cell Line, Tumor; Cell Proliferation; Chenodeoxycholic Acid; Cholic Acid; Coloring Agents; Deoxycholic Acid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Nucleosomes; Ovarian Neoplasms; Protein Kinase C; Tetrazolium Salts; Thiazoles; Ursodeoxycholic Acid | 2007 |
Safety profile of bevacizumab on cultured human corneal cells.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Biomarkers; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Endothelium, Corneal; Epithelium, Corneal; Fibroblasts; Humans; Immunoenzyme Techniques; Keratan Sulfate; Keratin-3; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Isoflurane preconditioning inhibited isoflurane-induced neurotoxicity.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Embryo, Mammalian; Isoflurane; L-Lactate Dehydrogenase; Leucine; Mutation; Neural Inhibition; Neurons; Presenilin-1; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Valine | 2007 |
Influence of Hypericum perforatum extract and its single compounds on amyloid-beta mediated toxicity in microglial cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cell Membrane; Cell Survival; Humans; Hypericum; L-Lactate Dehydrogenase; Microglia; Models, Chemical; Phagocytosis; Plant Extracts; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Effects of serine protease inhibitors on viability and morphology of Leishmania (Leishmania) amazonensis promastigotes.
Topics: Animals; Colorimetry; Leishmania mexicana; Microscopy, Electron; Parasitic Sensitivity Tests; Serine Endopeptidases; Serine Proteinase Inhibitors; Tetrazolium Salts; Thiazoles | 2007 |
Effect of medium pH on the cytotoxicity of hydrophilic statins.
Topics: Animals; Apoptosis; Caspases; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Fluorobenzenes; Humans; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle, Skeletal; Myoblasts; Pravastatin; Pyrimidines; Rats; Rhabdomyosarcoma, Embryonal; Rosuvastatin Calcium; Sulfonamides; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2007 |
Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity.
Topics: Animals; Cell Line; Cell Survival; Chromatography, Gas; Coloring Agents; Culture Media, Conditioned; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Methylmercury Compounds; Mitochondria; Neuroglia; Neurons; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 2007 |
Differential effect of galanin on proliferation of PC12 and B104 cells.
Topics: Animals; Bradykinin; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Galanin; Gene Expression; L-Lactate Dehydrogenase; Neuroblastoma; PC12 Cells; Peptide Fragments; Rats; Receptors, Galanin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
Growth inhibition and induction of differentiation by panaxydol in rat C6 glioma cells.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Size; Diynes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Glioma; Proliferating Cell Nuclear Antigen; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Protective effect of pine (Pinus morrisonicola Hay.) needle on LDL oxidation and its anti-inflammatory action by modulation of iNOS and COX-2 expression in LPS-stimulated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Blotting, Western; Cell Line; Chromans; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Humans; In Vitro Techniques; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; Mice; Nitric Oxide Synthase Type II; Oxidation-Reduction; Phenols; Picrates; Pinus; Polyphenols; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2008 |
Preclinical studies of treosulfan demonstrate potent activity in Ewing's sarcoma.
Topics: Animals; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Bisbenzimidazole; Blotting, Western; Busulfan; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; G1 Phase; Indicators and Reagents; Injections, Intraperitoneal; Mice; Mice, Nude; Sarcoma, Ewing; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2008 |
Design, synthesis and biological evaluation of substituted dioxodibenzothiazepines and dibenzocycloheptanes as farnesyltransferase inhibitors.
Topics: Animals; Cell Proliferation; Drug Design; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Leukemia L1210; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Sesquiterpene lactone suppresses vascular smooth muscle cell proliferation and migration via inhibition of cell cycle progression.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Chemotaxis; Cyclin D1; Depression, Chemical; G1 Phase; Indicators and Reagents; Lactones; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2007 |
Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.
Topics: Blotting, Western; Cell Adhesion Molecules; Cell Nucleus; Cell Survival; Chemokine CCL2; Cornus; Cytokines; Endothelial Cells; Glucosides; Humans; Indicators and Reagents; Inflammation Mediators; Intercellular Adhesion Molecule-1; NF-kappa B; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2007 |
Cytotoxicity of triterpenes isolated from Aceriphyllum rossii.
Topics: Antineoplastic Agents, Phytogenic; HL-60 Cells; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Plant Extracts; Saxifragaceae; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Triterpenes | 2007 |
Efficient transmicrocatheter delivery of functional fibroblasts with a bioengineered collagen gel-platinum microcoil complex: toward the development of endovascular cell therapy for cerebral aneurysms.
Topics: Biomedical Engineering; Catheterization; Cell Death; Cell Movement; Cell Survival; Cell Transplantation; Cells, Cultured; Collagen; Coloring Agents; Cross-Linking Reagents; DNA; Fibroblasts; Gels; Glutaral; Humans; Intracranial Aneurysm; Platinum; Tetrazolium Salts; Thiazoles | 2007 |
Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells.
Topics: Agaricales; Alpinia; Animals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flavonoids; Melanins; Melanoma, Experimental; Mice; Models, Chemical; Monophenol Monooxygenase; Mutagens; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2007 |
Bcl-2 overexpression in thyroid carcinoma cells increases sensitivity to Bcl-2 homology 3 domain inhibition.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Boronic Acids; Bortezomib; Carcinoma; Carcinoma, Medullary; Cell Line, Tumor; Colorimetry; Doxorubicin; Genes, bcl-2; Humans; Membrane Potentials; Oncogene Protein v-akt; Protease Inhibitors; Pyrazines; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Transcription, Genetic | 2007 |
Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: role of different immunosuppressive drugs.
Topics: Animals; Blotting, Western; Cell Line; Dendritic Cells; Dermatitis, Contact; Dexamethasone; Female; Fetus; Immunosuppressive Agents; Irritants; Langerhans Cells; Mice; Microscopy, Fluorescence; Nickel; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Pregnancy; Skin; Tetrazolium Salts; Thiazoles | 2007 |
Prediction of acute toxicity in HPCT-1E3 hepatocytoma cells with liver-like transport activities.
Topics: Animal Testing Alternatives; Animals; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Humans; Lethal Dose 50; Liver Neoplasms; Rats; Tetrazolium Salts; Thiazoles | 2007 |
In vitro toxicity assay using human bronchial epithelial cell, Beas-2B, for the screening of toxicological risk of dioxin-like compounds sampled from small sized Korean waste incineration plants.
Topics: Air Pollutants, Occupational; Antioxidants; Apoptosis; Bronchi; Cell Cycle; Cell Line; Cell Survival; Comet Assay; Dioxins; DNA; Epithelial Cells; Flow Cytometry; Gene Expression Regulation, Enzymologic; Humans; Incineration; Korea; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Refuse Disposal; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2007 |
Bis(4-hydroxybenzyl)sulfide: a sulfur compound inhibitor of histone deacetylase isolated from root extract of Pleuropterus ciliinervis.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Mass Spectrometry; Models, Chemical; Plant Extracts; Plant Roots; Sensitivity and Specificity; Sulfides; Sulfur; Sulfur Compounds; Tetrazolium Salts; Thiazoles | 2007 |
Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cisplatin; Comet Assay; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Hydrogen Peroxide; Mitochondrial Proteins; Models, Biological; Osteosarcoma; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Hepatoprotective activity of Phyllanthus amarus Schum. et. Thonn. extract in ethanol treated rats: in vitro and in vivo studies.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytokines; Ethanol; Liver; Male; Phyllanthus; Plant Extracts; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Triglycerides | 2007 |
Cytotoxicity of dental composites and their leached components.
Topics: 3T3 Cells; Analysis of Variance; Animals; Cell Survival; Chromatography, High Pressure Liquid; Composite Resins; Fibroblasts; Indicators and Reagents; Mice; Mice, Inbred BALB C; Reference Standards; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2007 |
Assessment of the astrogliotic responses of three human astrocytoma cell lines to ethanol, trimethyltin chloride and acrylamide.
Topics: Acrylamide; Astrocytoma; Brain Neoplasms; Cell Count; Cell Line, Tumor; Central Nervous System Depressants; Enzyme-Linked Immunosorbent Assay; Ethanol; Glial Fibrillary Acidic Protein; Gliosis; Humans; Mitochondria; Oxidoreductases; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds | 2007 |
Adenosine uptake-dependent C6 cell growth inhibition.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Animals; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Glioma; Hydrolysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thioinosine; Uridine | 2007 |
Coumarin derivatives protection against ROS production in cellular models of Abeta toxicities.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Coumarins; Free Radicals; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Models, Chemical; Mutation; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Colorimetry; Drug Evaluation, Preclinical; Ethnobotany; Ethnopharmacology; Humans; Indians, South American; Indicators and Reagents; Leishmania mexicana; Meglumine; Peru; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles | 2007 |
Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity.
Topics: Adult; Animals; Antimalarials; Aorta, Thoracic; Artemisinins; Capillaries; Cell Line; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Embryo, Mammalian; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Humans; Male; Neovascularization, Physiologic; Neural Tube; Pregnancy; Rats; Rats, Inbred F344; Sesquiterpenes; Teratogens; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
Toxicological evaluation of some Malaysian locally processed raw food products.
Topics: Analysis of Variance; Animals; Cell Line; Cell Survival; Comet Assay; Cytotoxins; DNA Damage; Fermentation; Fishes; Food; Food Analysis; Food Contamination; Food Preservatives; Hepatocytes; Humans; Liver; Malaysia; Metals, Heavy; Mutagens; Seafood; Tetrazolium Salts; Thiazoles | 2008 |
The use of MTT [3-(4, 5-dimethyl-2-thiazolyl) -2, 5-diphenyl -2H- tetrazolium bromide]-reduction as an indicator of the effects of strain-specific, polyclonal rabbit antisera on Candida albicans and C. krusei.
Topics: Animals; Antibodies, Fungal; Antibody Specificity; Candida; Candida albicans; Complement System Proteins; Guinea Pigs; Immune Sera; Oxidation-Reduction; Rabbits; Species Specificity; Tetrazolium Salts; Thiazoles | 2007 |
A preliminary study of the effects of an extract of Ligularia fischeri leaves on type II collagen-induced arthritis in DBA/1J mice.
Topics: Analysis of Variance; Animals; Cell Line; Cell Survival; Comet Assay; Cytotoxins; DNA Damage; Fermentation; Fishes; Food; Food Analysis; Food Contamination; Food Preservatives; Hepatocytes; Humans; Liver; Malaysia; Metals, Heavy; Mutagens; Seafood; Tetrazolium Salts; Thiazoles | 2008 |
The MTT assay yields a relatively lower result of growth inhibition than the ATP assay depending on the chemotherapeutic drugs tested.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lung Neoplasms; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 2008 |
Linker-based lecithin microemulsions for transdermal delivery of lidocaine.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Caprylates; Cell Survival; Chemical Phenomena; Chemistry, Physical; Electrolytes; Emulsions; Excipients; Humans; Lecithins; Lidocaine; Particle Size; Pentanols; Skin; Skin Absorption; Swine; Temperature; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques; Viscosity | 2008 |
Fructus schisandrae (Wuweizi)-containing compound inhibits secretion of HBsAg and HBeAg in hepatocellular carcinoma cell line.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Liver Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Schisandra; Tetrazolium Salts; Thiazoles | 2007 |
Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tumor; Cerulenin; DNA, Neoplasm; Enzyme Inhibitors; fas Receptor; Fatty Acid Synthases; Flow Cytometry; Genes, bcl-2; Humans; Melanoma; Microscopy, Confocal; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2007 |
In vitro effect of prion peptide PrP 106-126 on mouse macrophages: Possible role of macrophages in transport and proliferation for prion protein.
Topics: Animals; Cell Survival; Cells, Cultured; Female; Gene Expression Profiling; Humans; Macrophages, Peritoneal; Mice; Peptides; Prions; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Studies on the anti-tumor activities of the soy isoflavone daidzein on murine neuroblastoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Estrogens, Non-Steroidal; Flow Cytometry; Indicators and Reagents; Isoflavones; Kinetics; Mice; Neuroblastoma; Tetrazolium Salts; Thiazoles | 2007 |
Behaviors of keratinocytes and fibroblasts on films of PLA50-PEO-PLA50 triblock copolymers with various PLA segment lengths.
Topics: Cell Culture Techniques; Culture Media; Ethylene Oxide; Fibroblasts; Humans; Keratinocytes; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polyethylene Glycols; Polymers; Polystyrenes; Skin; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2008 |
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.
Topics: Angelica; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Benzimidazoles; Blotting, Western; Brain Neoplasms; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Chalcones; Fluorescent Dyes; Humans; Neuroblastoma; Tetrazolium Salts; Thiazoles | 2007 |
Active nanodiamond hydrogels for chemotherapeutic delivery.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Cell Line, Tumor; Colonic Neoplasms; Diamond; Doxorubicin; Drug Delivery Systems; Humans; Macrophages; Mice; Nanoparticles; Nanotechnology; Neoplasms; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.
Topics: Analysis of Variance; Anticholesteremic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Lovastatin; Receptors, TNF-Related Apoptosis-Inducing Ligand; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Survival; Cells; Chromatography, High Pressure Liquid; DNA Adducts; DNA Repair; Electrochemistry; Environmental Pollutants; Humans; Indicators and Reagents; Keratinocytes; Kinetics; Online Systems; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles | 2008 |
Toxicity evaluation of root canal sealers in vitro.
Topics: Animals; Biocompatible Materials; Cells, Cultured; Coloring Agents; Composite Resins; Dental Cements; Diffusion Chambers, Culture; Epoxy Resins; Fibroblasts; Materials Testing; Methacrylates; Mice; Root Canal Filling Materials; Silicones; Tetrazolium Salts; Thiazoles | 2008 |
Correlation of visual in vitro cytotoxicity ratings of biomaterials with quantitative in vitro cell viability measurements.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cell Proliferation; Cell Shape; Cell Survival; Colorimetry; Coloring Agents; Fibroblasts; Materials Testing; Mice; Organotin Compounds; Polyethylene; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tissue Adhesives; Toxicity Tests | 2008 |
Characterization of the transcriptional profile in primary astrocytes after oxidative stress induced by Paraquat.
Topics: Animals; Animals, Newborn; Astrocytes; Cell Survival; Cerebellum; Cloning, Molecular; Gene Expression Profiling; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Herbicides; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2008 |
Effects of calcium ion incorporation on osteoblast gene expression in MC3T3-E1 cells cultured on microstructured titanium surfaces.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Calcium; Cell Culture Techniques; Cell Differentiation; Ions; Materials Testing; Mice; Osteoblasts; Osteocalcin; Osteopontin; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2008 |
Biological activity of recombinant human growth factors released from biocompatible bone implants.
Topics: Alkaline Phosphatase; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Substitutes; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Fibroblast Growth Factor 2; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Prostheses and Implants; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta | 2008 |
Generation of magnetic nonviral gene transfer agents and magnetofection in vitro.
Topics: Cell Culture Techniques; Cells, Cultured; DNA; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Iron; Nanoparticles; Tetrazolium Salts; Thiazoles; Transfection | 2007 |
Role of Npm1 in proliferation, apoptosis and differentiation of neural stem cells.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Cell Differentiation; Cell Proliferation; Cricetinae; Female; Genes, p53; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mesocricetus; Mitogen-Activated Protein Kinase 1; Neurons; Nuclear Proteins; Nucleophosmin; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stem Cells; Tetrazolium Salts; Thiazoles | 2008 |
Blood micromolar concentrations of kaempferol afford protection against ischemia/reperfusion-induced damage in rat brain.
Topics: Animals; Brain; Caspase 9; Cell Death; Collagen Type XI; Disease Models, Animal; Dose-Response Relationship, Drug; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Kaempferols; Laminin; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Time Factors | 2007 |
pH-Controllable drug release using hydrogel encapsulated mesoporous silica.
Topics: Acrylic Resins; Circular Dichroism; Drug Compounding; Drug Delivery Systems; Hydrogels; Hydrogen-Ion Concentration; Microscopy, Electron, Transmission; Pharmaceutical Preparations; Proteins; Serum Albumin, Bovine; Silicon Dioxide; Tetrazolium Salts; Thiazoles | 2007 |
Impact of insulin-like growth factor-I on migration, proliferation and Akt-ERK signaling in early and late-passages of vascular smooth muscle cells.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Cells, Cultured; DNA; Electrophoresis, Polyacrylamide Gel; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oncogene Protein v-akt; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thymidine | 2007 |
5,19-cyclo-9beta,10xi-androstane-3,17-dione promotes neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells and improves passive avoidance learning impairment.
Topics: Androsterone; Animals; Astrocytoma; Avoidance Learning; Behavior, Animal; Cell Differentiation; Cell Line; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Inositol Phosphates; Learning Disabilities; Male; Mice; Nerve Growth Factor; Neurites; PC12 Cells; Proto-Oncogene Mas; Rats; Scopolamine; Tetrazolium Salts; Thiazoles | 2007 |
The effects of glutamate receptor antagonists on cerebellar granule cell survival and development.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Situ Nick-End Labeling; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Shikonin analogue (SA) 93/637 induces apoptosis by activation of caspase-3 in U937 cells.
Topics: Apoptosis; Caspase 3; Cell Survival; Cinnamates; DNA Fragmentation; Enzyme Activation; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Naphthoquinones; Neoplasms; Ribonucleases; Tetrazolium Salts; Thiazoles; Transcription, Genetic; U937 Cells | 2008 |
Polarization of caveolins and caveolae during migration of immortalized neurons.
Topics: Animals; beta-Cyclodextrins; Caveolae; Caveolins; Cell Line, Transformed; Cell Movement; Chemotaxis; Cholesterol; Gonadotropin-Releasing Hormone; Indoles; Mice; Microscopy, Electron, Transmission; Neurons; Tetrazolium Salts; Thiazoles | 2008 |
Failure of MTT as a toxicity testing agent for mesoporous silicon microparticles.
Topics: Caco-2 Cells; Cell Survival; Coloring Agents; Drug Carriers; Humans; Oxidation-Reduction; Particle Size; Porosity; Sensitivity and Specificity; Silicon; Surface Properties; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2007 |
Release of MCP-1 and IL-8 from lung epithelial cells exposed to volatile organic compounds.
Topics: Cell Line; Cell Line, Tumor; Cell Survival; Chemokine CCL2; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Hydrocarbons; Hydrocarbons, Aromatic; Inflammation; Interleukin-6; Interleukin-8; Lung; Organic Chemicals; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Volatilization | 2008 |
Synthesis and antiproliferative in-vitro activity of natural flavans and related compounds.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Flavones; Humans; Stereoisomerism; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2007 |
Hydralazine inhibits compression and acrolein-mediated injuries in ex vivo spinal cord.
Topics: Acrolein; Analysis of Variance; Animals; Antihypertensive Agents; Dextrans; Drug Interactions; Glutathione; Guinea Pigs; Hydralazine; In Vitro Techniques; L-Lactate Dehydrogenase; Neural Conduction; Rhodamines; Spinal Cord Injuries; Superoxides; Tetrazolium Salts; Thiazoles | 2008 |
Proteasome inhibition is associated with manganese-induced oxidative injury in PC12 cells.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Apoptosis; Cell Count; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Manganese Compounds; Oxidative Stress; PC12 Cells; Proteasome Endopeptidase Complex; Protein Carbonylation; Rats; Tetrazolium Salts; Thiazoles; Trace Elements | 2007 |
Farnesyl transferase inhibitors induce neuroprotection by inhibiting Ha-Ras signalling pathway.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Agonists; Farnesyltranstransferase; Male; Maleates; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
A novel anti-cancer substance, MK615, from ume, a variety of Japanese apricot, inhibits growth of hepatocellular carcinoma cells by suppressing Aurora A kinase activity.
Topics: Aurora Kinases; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Plant Extracts; Protein Serine-Threonine Kinases; Prunus; Tetrazolium Salts; Thiazoles | 2007 |
Neurokinin-3 peptide instead of neurokinin-1 synergistically exacerbates kainic acid-inducing degeneration of neurons in the substantia nigra of mice.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Drug Synergism; Fluoresceins; Kainic Acid; Male; Mice; Mice, Inbred Strains; Nerve Degeneration; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Neurons; Organic Chemicals; Peptide Fragments; Pyrrolidonecarboxylic Acid; Quinolines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Substantia Nigra; Tetrazolium Salts; Thiazoles | 2008 |
Developmental neurotoxicity role of cyclophosphamide on post-neural tube closure of rodents in vitro and in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Annexin A5; Antineoplastic Agents, Alkylating; Apoptosis; Brain; Cell Survival; Comet Assay; Cyclophosphamide; Female; Fetal Development; Flow Cytometry; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Neural Tube Defects; Neurons; Neurotoxicity Syndromes; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Tetrazolium Salts; Thiazoles | 2007 |
Effect of Bcl-2 and Bax on survival of side population cells from hepatocellular carcinoma cells.
Topics: bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Proliferation; Fluorescent Antibody Technique; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2007 |
Cytotoxicity of metal ions to human oligodendroglial cells and human gingival fibroblasts assessed by mitochondrial dehydrogenase activity.
Topics: Cadmium; Cell Survival; Cells, Cultured; Chromium; Cobalt; Coloring Agents; Copper; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Gold; Humans; Lethal Dose 50; Materials Testing; Mercury; Metals, Heavy; Methylmercury Compounds; Mitochondria; Nickel; Oligodendroglia; Oxidoreductases; Tetrazolium Salts; Thiazoles | 2008 |
PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery? A comparative study of particle stability during nebulization.
Topics: Adhesiveness; Administration, Inhalation; Antibiotics, Antitubercular; Cell Line; Chemical Phenomena; Chemistry, Physical; Chitosan; Diffusion; Drug Compounding; Drug Delivery Systems; Drug Stability; Electrochemistry; Emulsions; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Mucins; Mucous Membrane; Nebulizers and Vaporizers; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Alveoli; Rifampin; Solvents; Tetrazolium Salts; Thiazoles | 2008 |
Induction of mitochondria-dependent apoptosis by Abrus agglutinin derived peptides in human cervical cancer cell.
Topics: Abrus; Agglutinins; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; DNA Fragmentation; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HeLa Cells; Humans; Indicators and Reagents; Membrane Potentials; Mitochondria; Molecular Weight; Peptides; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2008 |
Comparative evaluation of the effects of statins on human stem and cancer cells in vitro.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Embryonic Stem Cells; Fluorouracil; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Phase-Contrast; Polymerase Chain Reaction; Terpenes; Tetrazolium Salts; Thiazoles | 2007 |
Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Cell Proliferation; Cytosol; Dopamine; Drug Interactions; Green Fluorescent Proteins; L-Lactate Dehydrogenase; Methamphetamine; PC12 Cells; Potassium Chloride; Rats; Reserpine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2007 |
Targeting of Sp1 transcription factor: a novel therapeutic approach for keloids, an in vitro analysis.
Topics: Antineoplastic Agents; Case-Control Studies; Cell Nucleus; Cell Proliferation; Cells, Cultured; Coculture Techniques; Collagen; Down-Regulation; Extracellular Matrix; Fibroblasts; Fibronectins; Humans; Keloid; Keratinocytes; Mitoxantrone; Sp1 Transcription Factor; Tetrazolium Salts; Thiazoles; Up-Regulation | 2007 |
Protective effects of olanzapine and haloperidol on serum withdrawal-induced apoptosis in SH-SY5Y cells.
Topics: Analysis of Variance; Antipsychotic Agents; Apoptosis; Benzodiazepines; beta Catenin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Haloperidol; Humans; Neuroblastoma; Olanzapine; Proto-Oncogene Proteins c-bcl-2; Serum; Tetrazolium Salts; Thiazoles | 2008 |
Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; bcl-X Protein; Benzimidazoles; Blotting, Western; Caspase 3; Caspase 9; Cell Hypoxia; Cell Line; Cell Survival; Cells, Cultured; Eicosanoids; Fluorescent Antibody Technique; Fluorescent Dyes; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; X-Linked Inhibitor of Apoptosis Protein | 2008 |
Aberrant expression of Fra-1 in estrogen receptor-negative breast cancers and suppression of their propagation in vivo by ascochlorin, an antibiotic that inhibits cellular activator protein-1 activity.
Topics: Alkenes; Animals; Antibiotics, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Longevity; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Phenols; Proto-Oncogene Proteins c-fos; Receptors, Estrogen; Survival Analysis; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Xenograft Model Antitumor Assays | 2007 |
Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha.
Topics: Antifungal Agents; Ascomycota; Bacteria; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Drug Screening Assays, Antitumor; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Fruiting Bodies, Fungal; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
Chotosan enhances macrophage colony-stimulating factor mRNA expression in the ischemic rat brain and C6Bu-1 glioma cells.
Topics: Animals; Brain Chemistry; Brain Ischemia; Brain Neoplasms; Carotid Artery, Common; Carotid Stenosis; Cell Line, Tumor; Cell Survival; Drugs, Chinese Herbal; Glioma; Macrophage Colony-Stimulating Factor; Male; Protein Kinase C; Rats; Rats, Wistar; Receptors, Colony-Stimulating Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatin; DNA, Neoplasm; Enzyme Induction; Ethanol; Flow Cytometry; Furans; Humans; Lactones; Lignans; Metabolic Detoxication, Phase II; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Plant Extracts; Saussurea; Sesquiterpenes; Solvents; Tetrazolium Salts; Thiazoles | 2007 |
Safe and effective permeation enhancers for oral drug delivery.
Topics: Caco-2 Cells; Drug Delivery Systems; Electric Impedance; Epithelium; Excipients; Humans; Intestinal Absorption; Permeability; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2008 |
Preparation and characterization of amidated pectin based hydrogels for drug delivery system.
Topics: Amides; Animals; Biocompatible Materials; Blood; Drug Delivery Systems; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Kinetics; Melanoma, Experimental; Mice; Pectins; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Wound Healing; X-Ray Diffraction | 2008 |
Photodynamic therapy using talaporfin sodium for synovial membrane from rheumatoid arthritis patients and collagen-induced arthritis rats.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Coloring Agents; Disease Models, Animal; Fibroblasts; Humans; Injections, Intra-Articular; Laser Therapy; Male; Mice; Mice, SCID; Photosensitizing Agents; Phototherapy; Porphyrins; Radiography; Rats; Rats, Inbred Lew; Synovial Membrane; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 2008 |
1-Methylhydantoin cytotoxicity on renal proximal tubular cells in vitro.
Topics: Acetylglucosaminidase; Annexin A5; Apoptosis; Cell Line; Humans; Hydantoins; Kidney Tubules, Proximal; Microscopy, Fluorescence; Propidium; Tetrazolium Salts; Thiazoles | 2007 |
The use of doxycycline as a protectant against sulphur mustard in HaCaT cells.
Topics: Anti-Bacterial Agents; Cell Count; Cell Cycle; Cell Line; Chemical Warfare Agents; Coloring Agents; Doxycycline; Flow Cytometry; Gentian Violet; Humans; Keratinocytes; Microscopy, Phase-Contrast; Mustard Gas; Tetrazolium Salts; Thiazoles | 2008 |
Insulin administration confers diabetes-preventive properties to NOD mice derived dendritic cells.
Topics: Animals; Autoantigens; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Cytokines; Dendritic Cells; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Interleukin-2 Receptor alpha Subunit; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Prediabetic State; Spleen; T-Lymphocytes, Regulatory; Tetrazolium Salts; Thiazoles | 2007 |
Immunomodulatory effects of erythromycin and its derivatives on human T-lymphocyte in vitro.
Topics: Anti-Bacterial Agents; Blotting, Western; Cell Proliferation; Cells, Cultured; Erythromycin; Flow Cytometry; Humans; Immunologic Factors; In Situ Nick-End Labeling; Jurkat Cells; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2007 |
Development and characterization of P-glycoprotein 1 (Pgp1, ABCB1)-mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Data Interpretation, Statistical; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fish Diseases; Fishes; Glutathione; Glutathione Transferase; Liver Neoplasms; Microscopy, Fluorescence; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Xenobiotics | 2008 |
As2O3-induced oxidative stress and cycle progression in a human intestinal epithelial cell line (Caco-2).
Topics: Arsenic Trioxide; Arsenicals; Caco-2 Cells; Cell Cycle; Cell Survival; G1 Phase; G2 Phase; Humans; Membrane Potentials; Mitochondria; Mitochondrial Membranes; Oxidative Stress; Oxides; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Evidence of increased reactive species formation by retinol, but not retinoic acid, in PC12 cells.
Topics: Animals; Antioxidants; Calcium; Cell Survival; Chelating Agents; Egtazic Acid; Fluorescent Dyes; Iron Chelating Agents; Kinetics; PC12 Cells; Phenanthrolines; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tretinoin; Vitamin A | 2008 |
An orthotopic skull base model of malignant meningioma.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Meningeal Neoplasms; Meningioma; Mice; Mice, Nude; Neoplasm Transplantation; Skull Base Neoplasms; Temozolomide; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Proteins | 2008 |
Relationship between in vitro chemosensitivity assessed with MTT assay and clinical outcomes in 103 patients with acute leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2007 |
Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression.
Topics: Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Cell Proliferation; Dinoprostone; Fibronectins; Humans; Lignans; Lipopolysaccharides; Lymphocytes; Mitogens; Nitric Oxide; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Tumor necrosis factor alpha-mediated nitric oxide production enhances manganese superoxide dismutase nitration and mitochondrial dysfunction in primary neurons: an insight into the role of glial cells.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Coculture Techniques; Immunohistochemistry; Mice; Mice, Knockout; Mitochondria; Neuroglia; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Tyrosine | 2008 |
Characterization and antitumor activity of triethylene tetramine, a novel telomerase inhibitor.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Blotting, Western; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Doxorubicin; Female; HeLa Cells; Humans; Indicators and Reagents; Mice; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma 180; Telomerase; Tetrazolium Salts; Thiazoles; Trientine | 2008 |
Minimalism in fabrication of self-organized nanogels holding both anti-cancer drug and targeting moiety.
Topics: Antineoplastic Agents; Carbohydrate Sequence; Cell Survival; Doxorubicin; Drug Delivery Systems; Excipients; Folic Acid; Glucans; Humans; KB Cells; Light; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Molecular Sequence Data; Nanoparticles; Scattering, Radiation; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Development of an in vitro reproductive screening assay for novel pharmaceutical compounds.
Topics: Animals; Cell Count; Cell Line, Tumor; Cell Proliferation; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethylene Glycol; Gentian Violet; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Organosilicon Compounds; Progesterone; Radioimmunoassay; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2008 |
Evaluation of the transfection property of a peptide ligand for the fibroblast growth factor receptor as part of PEGylated polyethylenimine polyplex.
Topics: Cells, Cultured; DNA; Electrochemistry; Flow Cytometry; Gene Transfer Techniques; Humans; Indicators and Reagents; Ligands; Magnetic Resonance Spectroscopy; Particle Size; Peptides; Plasmids; Polyethylene Glycols; Polyethyleneimine; Receptors, Fibroblast Growth Factor; Surface Properties; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Effect of nitride film coatings on cell compatibility.
Topics: Alloys; Cell Adhesion; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Chromium Alloys; Coated Materials, Biocompatible; Coloring Agents; Cytoskeleton; Dental Alloys; Dental Polishing; Fibroblasts; Gingiva; Humans; Materials Testing; Microscopy, Fluorescence; Surface Properties; Surface Tension; Tetrazolium Salts; Thiazoles; Time Factors; Titanium; Wettability | 2008 |
Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenic E. coli is enhanced by TNF-alpha.
Topics: Adenosine Triphosphate; Blotting, Western; Caspases; Cell Death; Cell Line; Cells, Cultured; Dinitrophenols; Electric Impedance; Epithelium; Escherichia coli Infections; Feedback, Physiological; Humans; Interleukin-1beta; Interleukin-6; Leupeptins; Lipopolysaccharides; Macrophages; NF-kappa B; Nitriles; Permeability; Stress, Physiological; Sulfones; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Uncoupling Agents | 2008 |
Selective regulation of neurosteroid biosynthesis in human neuroblastoma cells under hydrogen peroxide-induced oxidative stress condition.
Topics: Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Letrozole; Neuroblastoma; Nitriles; Oxidative Stress; Serum; Steroids; Tetrazolium Salts; Thiazoles; Time Factors; Triazoles | 2008 |
An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Blotting, Western; Carboplatin; Cell Line, Tumor; Female; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Mice; Mice, Nude; Ovarian Neoplasms; Rhodamines; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2008 |
In vitro study on different cell response to spherical hydroxyapatite nanoparticles.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Proliferation; Durapatite; Humans; Materials Testing; Mice; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2008 |
Cell cycle arrest and differentiation induction by 5,7-dimethoxycoumarin in melanoma cell lines.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Coumarins; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Melanoma; Melanoma, Experimental; Mice; Tetrazolium Salts; Thiazoles; Trypan Blue | 2008 |
Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Apoptosis; Benzimidazoles; Benzo(a)pyrene; Blotting, Western; Cell Line, Tumor; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Isoenzymes; Luciferases; Mutagens; Phosphorylation; Plasmids; Polycyclic Aromatic Hydrocarbons; Pyrenes; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2008 |
Photodynamic effect of protoporphyrin diarginate (PPArg2) on methicillin-resistant Staphylococcus aureus and human dermal fibroblasts.
Topics: Arginine; Dermis; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fibroblasts; Humans; Light; Methicillin; Methicillin Resistance; Models, Biological; Photochemistry; Photosensitizing Agents; Protoporphyrins; Skin; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2008 |
Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells.
Topics: Analysis of Variance; Apoptosis; Camptotheca; Camptothecin; Cell Line; Cell Proliferation; DNA; Down-Regulation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Growth Inhibitors; Humans; Isomerism; Keratinocytes; Polymerase Chain Reaction; Psoriasis; Telomerase; Tetrazolium Salts; Thiazoles | 2008 |
Role of calpain and caspase in beta-amyloid-induced cell death in rat primary septal cultured neurons.
Topics: Amyloid beta-Peptides; Animals; Calcium-Binding Proteins; Calpain; Caspases; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Microscopy, Electron, Scanning; Microtubule-Associated Proteins; Neurofibrillary Tangles; Neurons; Oligopeptides; Peptide Fragments; Pregnancy; Rats; Septum of Brain; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
The anticancer effect of protein-extract from Bidens alba in human colorectal carcinoma SW480 cells via the reactive oxidative species- and glutathione depletion-dependent apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bidens; Caspases; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cytochromes c; Cytosol; Flow Cytometry; Glutathione; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Mitochondria; Plant Extracts; Plant Proteins; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2008 |
Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells.
Topics: Antioxidants; Apigenin; Blotting, Western; Cell Survival; Cytokines; Flavonoids; Flavonols; Glutathione; Hepatocytes; Humans; Inflammation; Kaempferols; Liver; Oxidation-Reduction; Quercetin; Reactive Nitrogen Species; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2008 |
The protective effect of functional connexin43 channels on a human epithelial cell line exposed to oxidative stress.
Topics: Blotting, Western; Cell Communication; Cell Line; Cell Survival; Connexin 26; Connexin 43; Connexins; Cytoprotection; Fluorescent Antibody Technique, Indirect; Gap Junctions; Gene Silencing; Humans; Microscopy, Confocal; Oxidative Stress; Pigment Epithelium of Eye; RNA Interference; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 2008 |
Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts.
Topics: Blotting, Western; Cell Line; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 1; Polysaccharides; Radiation-Protective Agents; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2008 |
Novel method for selecting immunosuppressive histone deacetylase (HDAC) inhibitors with minimal thrombocytopenia.
Topics: Animals; Cell Survival; Drug Evaluation, Preclinical; Enzyme Inhibitors; GATA1 Transcription Factor; Genes, Reporter; Heart Transplantation; Histone Deacetylase Inhibitors; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Male; Plasmids; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Thrombocytopenia; Transplantation, Heterotopic | 2008 |
Cytotoxicity of labdane-type diterpenoids from Hedychium forrestii.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Crystallography, X-Ray; Diterpenes; Drug Screening Assays, Antitumor; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Conformation; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Zingiberaceae | 2008 |
Penicillenols from Penicillium sp. GQ-7, an endophytic fungus associated with Aegiceras corniculatum.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Fermentation; Humans; Magnetic Resonance Spectroscopy; Penicillium; Primulaceae; Pyrrolidinones; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
A new method for antimicrobial susceptibility testing of in vitro-cultured bacteria by means of resonance light scattering technique.
Topics: Anti-Bacterial Agents; Coloring Agents; Flavonoids; Humans; Light; Marchantia; Methicillin Resistance; Microbial Sensitivity Tests; Oxidation-Reduction; Plant Extracts; Scattering, Radiation; Spectrometry, Fluorescence; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2008 |
Influence of oxidized low-density lipoproteins (LDL) on the viability of osteoblastic cells.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Humans; Lipoproteins, LDL; Lysosomes; Mice; Osteoblasts; Osteoporosis; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2008 |
Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Shape; Cell Survival; Cytoprotection; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Microscopy, Electron, Transmission; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Plant Extracts; Rotenone; Tetrazolium Salts; Thiazoles | 2008 |
Intracellular reactive oxygen species in monocytes generated by photosensitive chromophores activated with blue light.
Topics: Cell Line; Chlorophyll; Chlorophyllides; Coloring Agents; Fluoresceins; Fluorescent Dyes; Humans; Light; Mitochondria; Monocytes; Photosensitizing Agents; Polylysine; Porphyrins; Radiation-Sensitizing Agents; Reactive Oxygen Species; Riboflavin; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2008 |
Cytotoxic effects of treosulfan and busulfan against leukemic cells of pediatric patients.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Busulfan; Caspase 3; Cell Line, Tumor; Child; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Killer Cells, Natural; Leukemia; Stem Cells; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Vidarabine | 2008 |
Biocompatibility of polyhydroxybutyrate microspheres: in vitro and in vivo evaluation.
Topics: 3-Hydroxybutyric Acid; Animals; Biocompatible Materials; Cell Survival; In Vitro Techniques; Inflammation; Materials Testing; Mice; Microspheres; Necrosis; NIH 3T3 Cells; Polymers; Prohibitins; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
QSAR models for predicting in vivo aquatic toxicity of chlorinated alkanes to fish.
Topics: Algorithms; Animals; Artificial Intelligence; Cell Survival; Chemical Phenomena; Chemistry, Physical; CHO Cells; Cricetinae; Cricetulus; Fishes; Hydrocarbons, Chlorinated; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction.
Topics: Acrolein; DNA Damage; Free Radicals; Gene Expression Regulation; Glutathione Transferase; Humans; Lipid Peroxidation; Mitochondria; Models, Biological; Oxidative Stress; Pigment Epithelium of Eye; Smoke; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thioctic Acid | 2008 |
Influence of carvacrol on proliferation and survival of porcine lymphocytes and intestinal epithelial cells in vitro.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Caspase 3; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Cell Survival; Cymenes; Enterocytes; Enzyme Activation; Epithelial Cells; Flow Cytometry; Intestines; Lymphocyte Subsets; Lymphocytes; Monoterpenes; Swine; Tetrazolium Salts; Thiazoles | 2008 |
Cytotoxic effects of different concentrations of chlorhexidine.
Topics: Animals; Anti-Infective Agents, Local; Buffers; Cell Adhesion; Cell Line; Cell Membrane; Cell Shape; Chlorhexidine; Coloring Agents; Dose-Response Relationship, Drug; Hydrogen Peroxide; Mice; Odontoblasts; Oxidants; Sodium Chloride; Tetrazolium Salts; Thiazoles | 2007 |
Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.
Topics: Animals; Apoptosis; Arginine; Blood Proteins; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Drug Screening Assays, Antitumor; Endocytosis; Flow Cytometry; HeLa Cells; Humans; Membrane Potentials; Microscopy, Confocal; Oligopeptides; Proteoglycans; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Transferrin | 2008 |
Spin-labeled rifamycin: biological activity.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Cell Line, Tumor; Cell Survival; Female; Gamma Rays; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mice; Microbial Sensitivity Tests; Oxidative Stress; Rifamycins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spin Labels; Tetrazolium Salts; Thiazoles | 2008 |
Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices.
Topics: Animals; Benzene Derivatives; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Lipid Peroxidation; Male; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Organoselenium Compounds; Oxidants; Phosphorylation; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Antimicrobial activity does not predict cytokine response to adrenomedullin or its shortened derivatives.
Topics: Adrenomedullin; Animals; Anti-Infective Agents; Cell Line; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Gingiva; Humans; Keratinocytes; Mouth Mucosa; Peptides; Rats; Tetrazolium Salts; Thiazoles | 2007 |
Antisense RNA of survivin gene inhibits the proliferation of leukemia cells and sensitizes leukemia cell line to taxol-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Flow Cytometry; HL-60 Cells; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Leukemia; Microtubule-Associated Proteins; Neoplasm Proteins; Paclitaxel; RNA, Antisense; Survivin; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis of water soluble PEGylated magnetic complexes using mPEG-fatty acid for biomedical applications.
Topics: Biocompatible Materials; Drug Carriers; Fatty Acids; Ferric Compounds; HeLa Cells; Humans; Magnetics; Manganese Compounds; Nanoparticles; Polyethylene Glycols; Polymers; Solubility; Tetrazolium Salts; Thiazoles; Tissue Adhesions; Water | 2008 |
A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro.
Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Circular Dichroism; Cytotoxicity Tests, Immunologic; Hepacivirus; Hepatitis C; Humans; In Vitro Techniques; Molecular Sequence Data; Peptides; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Virus Replication | 2008 |
Characterization of oxidized low-density lipoprotein-induced hormesis-like effects in osteoblastic cells.
Topics: Animals; Apoptosis; Atherosclerosis; Cell Line; Cell Proliferation; Chloroquine; Humans; Lipoproteins, LDL; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoporosis; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Structure-activity studies of Ti(IV) complexes: aqueous stability and cytotoxic properties in colon cancer HT-29 cells.
Topics: Antineoplastic Agents; Apoproteins; Dose-Response Relationship, Drug; Drug Stability; HT29 Cells; Humans; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Organometallic Compounds; Solutions; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Titanium; Transferrin | 2008 |
Panaxydol and panaxynol protect cultured cortical neurons against Abeta25-35-induced toxicity.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; bcl-2-Associated X Protein; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Diynes; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Fatty Alcohols; Gene Expression Regulation; In Situ Nick-End Labeling; Microscopy, Confocal; Neurons; Neuroprotective Agents; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Endosomal colocalization of melanocortin-3 receptor and beta-arrestins in CAD cells with altered modification of AKT/PKB.
Topics: Androstadienes; Antineoplastic Agents; Arrestins; beta-Arrestins; Blotting, Western; Brain Stem; Cell Proliferation; Cells, Cultured; Endosomes; Humans; Microscopy, Fluorescence; Oncogene Protein v-akt; Plasmids; Receptor, Melanocortin, Type 3; Receptors, G-Protein-Coupled; Ribonucleosides; Tetrazolium Salts; Thiazoles; Transfection; Ubiquitin; Wortmannin | 2008 |
Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell neurotoxicity.
Topics: Analysis of Variance; Arginine; Carbon Isotopes; Cell Line; Computational Biology; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; L-Lactate Dehydrogenase; Lipopolysaccharides; Mass Spectrometry; Microglia; Monocytes; Neuroblastoma; Neurotoxins; Prolyl Oligopeptidases; Serine Endopeptidases; Tetrazolium Salts; Thiazoles | 2008 |
Cytotoxicity of two autopolymerized acrylic resins used in orthodontics.
Topics: Acrylic Resins; Animals; Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media, Conditioned; Dental Materials; Epithelial Cells; Fibroblasts; HeLa Cells; Humans; Materials Testing; Methylmethacrylates; Mice; NIH 3T3 Cells; Orthodontic Appliances; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Efficacies of beta-L-D4A against Hepatitis B virus in 2.2.15 cells.
Topics: Antiviral Agents; Cell Line; Dideoxyadenosine; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Models, Chemical; Tetrazolium Salts; Thiazoles; Virus Replication | 2008 |
Telomerase-specific oncolytic virotherapy for human hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fibroblasts; Humans; Liver Neoplasms; Microscopy, Fluorescence; Oncolytic Virotherapy; Promoter Regions, Genetic; RNA, Messenger; Telomerase; Tetrazolium Salts; Thiazoles; Virus Replication | 2008 |
Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells.
Topics: Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Beclin-1; Brain; Calcium; Cardenolides; Cell Movement; Cell Proliferation; Cells, Cultured; Glioblastoma; Green Fluorescent Proteins; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Proteins; Sodium-Potassium-Exchanging ATPase; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Inhibitory effects of a novel ascorbic derivative, disodium isostearyl 2-O-L-ascorbyl phosphate on melanogenesis.
Topics: Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Melanins; Melanoma; Monophenol Monooxygenase; Skin; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions.
Topics: Adenocarcinoma; Apoptosis; Aurora Kinase A; Aurora Kinases; Biomarkers, Tumor; Blotting, Western; Camptothecin; Coloring Agents; Cytochromes c; Enzyme Inhibitors; Esophageal Neoplasms; Flow Cytometry; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Luciferases; Luminescent Agents; Polymerase Chain Reaction; Protein Array Analysis; Protein Serine-Threonine Kinases; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2008 |
Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells.
Topics: Animals; Antineoplastic Agents; Biotransformation; Blotting, Western; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Chromatography, Ion Exchange; Epidermal Growth Factor; ErbB Receptors; Genes, fos; Genes, jun; Genes, Reporter; Indicators and Reagents; Laminaria; Mice; Phosphorylation; Polysaccharides; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1 | 2008 |
Anti-tumor effect of Coriolus versicolor methanol extract against mouse B16 melanoma cells: in vitro and in vivo study.
Topics: Agaricales; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flow Cytometry; L-Lactate Dehydrogenase; Macrophages; Melanoma, Experimental; Methanol; Mice; Mice, Inbred C57BL; Necrosis; Phenols; Solvents; Terpenes; Tetrazolium Salts; Thiazoles; Trypan Blue | 2008 |
Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures.
Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Chlorides; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; L-Lactate Dehydrogenase; Manganese Compounds; Membrane Potential, Mitochondrial; Mitochondria; Neurotoxins; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Novel biodegradable poly(disulfide amine)s for gene delivery with high efficiency and low cytotoxicity.
Topics: 3T3 Cells; Animals; Buffers; Cell Line, Tumor; Cell Survival; Chromatography, Gel; DNA; Drug Delivery Systems; Gene Transfer Techniques; Genes, Reporter; HeLa Cells; Humans; Indicators and Reagents; Light; Luciferases; Magnetic Resonance Spectroscopy; Mice; Particle Size; Polyamines; Scattering, Radiation; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Synthesis of multifunctional polyvinylsaccharide containing controllable amounts of biospecific ligands.
Topics: 3T3 Cells; Adsorption; Aldehydes; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Survival; Electrophoresis, Polyacrylamide Gel; Humans; Indicators and Reagents; Kinetics; Ligands; Mice; Oligopeptides; Polylysine; Polysaccharides; Polyvinyls; Ribonuclease, Pancreatic; Ribonucleases; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thermodynamics; Thiazoles; Tissue Engineering; Transforming Growth Factor beta | 2008 |
Tumor necrosis factor receptor-associated death domain mediated neuronal death contributes to the glial activation and subsequent neuroinflammation in Japanese encephalitis.
Topics: Animals; Astrocytes; Blotting, Western; Cell Death; Cell Line; Cyclooxygenase 2; Cytokines; Encephalitis, Japanese; Female; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Male; Mice; Mice, Inbred BALB C; Microglia; Neurons; Nitric Oxide Synthase Type II; Receptors, Chemokine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; TNF Receptor-Associated Death Domain Protein; Vascular Cell Adhesion Molecule-1; Viral Load | 2008 |
N-Substituted piperazinyl quinolones as potential cytotoxic agents: structure-activity relationships study.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Colorimetry; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Quinolones; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2009 |
Lack of robust protective effect of quercetin in two types of 6-hydroxydopamine-induced parkinsonian models in rats and dopaminergic cell cultures.
Topics: Amphetamine; Animals; Antioxidants; Apomorphine; Behavior, Animal; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Male; Motor Activity; Neuroblastoma; Oxidopamine; Parkinson Disease; Quercetin; Rats; Rats, Wistar; Substantia Nigra; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2008 |
Isolation and characterization of new lactam compounds that inhibit lung and colon cancer cells from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) bran.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Coix; Colonic Neoplasms; HT29 Cells; Humans; Lactams; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; DNA Primers; Esophageal Neoplasms; Flavones; Flavonols; G2 Phase; Humans; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tetrazolium Salts; Thiazoles | 2008 |
Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kappaB-dependent iNOS and proinflammatory cytokines production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Line; Cytokines; Densitometry; Edema; Enzyme-Linked Immunosorbent Assay; Flavanones; Glycyrrhizic Acid; Hypolipidemic Agents; Interleukin-1beta; Interleukin-6; Luciferases; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Nitrites; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2.
Topics: Aminobutyrates; Angiogenesis Inhibitors; Benzopyrans; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cloning, Molecular; Cytoplasm; Endothelial Cells; Enzyme Activators; Genes, Reporter; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Luciferases; Procollagen-Proline Dioxygenase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Cytotoxicity of silica-glass fiber reinforced composites.
Topics: Acrylates; Animals; Cell Survival; Coloring Agents; Composite Resins; Cross-Linking Reagents; Dental Materials; Ethylene Glycols; Fibroblasts; Glass; Materials Testing; Methacrylates; Methylmethacrylate; Mice; Polymethacrylic Acids; Polymethyl Methacrylate; Polyvinyls; Silicon Dioxide; Surface Properties; Temperature; Tetrazolium Salts; Thiazoles | 2008 |
Neuromedin U inhibits inflammation-mediated memory impairment and neuronal cell-death in rodents.
Topics: Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; Data Interpretation, Statistical; DNA; Enzyme Inhibitors; Hippocampus; Inflammation; Lipopolysaccharides; Male; Memory Disorders; Memory, Short-Term; Mice; Neuroglia; Neurons; Neuropeptides; Proadifen; Psychomotor Performance; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2008 |
Stir-baked Fructus gardeniae (L.) extracts inhibit matrix metalloproteinases and alter cell morphology.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gardenia; Humans; Matrix Metalloproteinase Inhibitors; Plant Extracts; Protease Inhibitors; Tetrazolium Salts; Thiazoles | 2008 |
Anti-HIV-1 activities of compounds isolated from the medicinal plant Rhus chinensis.
Topics: Anti-HIV Agents; Cell Line; Enzyme-Linked Immunosorbent Assay; Giant Cells; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Stems; Rhus; Tetrazolium Salts; Thiazoles | 2008 |
Distinct H2O2 concentration promotes proliferation of tumour cells after transient oxygen/glucose deprivation.
Topics: Animals; Antioxidants; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glucose; Hydrogen Peroxide; Models, Biological; Neoplasms; Oxygen; Rats; Reperfusion Injury; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Inhibition by vitamin C of apoptosis induced by N-nitrosamines in HepG2 and HL-60 cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Carcinogens; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme System; Excitatory Amino Acid Agonists; HL-60 Cells; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Liver Neoplasms; N-Methylaspartate; N-Nitrosopyrrolidine; Nitrosamines; Tetrazolium Salts; Thiazoles | 2008 |
Microplate assay for detection of bacterial contamination in tissue culture media.
Topics: Bacteria; Bacteriological Techniques; Crystallization; Culture Media; Drug Contamination; Formazans; Tetrazolium Salts; Thiazoles | 1997 |
Suitability of macrophage inflammatory protein-1beta production by THP-1 cells in differentiating skin sensitizers from irritant chemicals.
Topics: Allergens; Animal Testing Alternatives; Animals; Biological Assay; Biomarkers; Cell Line; Cell Proliferation; Cells, Cultured; Chemokine CCL4; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Humans; Inhibitory Concentration 50; Irritants; Monocytes; Skin; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2008 |
Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment.
Topics: alpha-Synuclein; Alzheimer Disease; Amphotericin B; Amyloid; Amyloid beta-Peptides; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Molecular Weight; Neuroblastoma; Peptide Fragments; Ruthenium Red; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Patterned growth of neuronal cells on modified diamond-like carbon substrates.
Topics: Animals; Biocompatible Materials; Carbon; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Coated Materials, Biocompatible; Diamond; Embryo, Mammalian; Mice; Neuroblastoma; Neurons; Oxidation-Reduction; Phosphorus; Polylysine; Polystyrenes; Rats; Rats, Wistar; Spectrum Analysis, Raman; Substrate Specificity; Tetrazolium Salts; Thiazoles | 2008 |
Endothelin (ET)-1 and ET-3 promote expression of c-fos and c-jun in human choriocarcinoma via ET(B) receptor-mediated G(i)- and G(q)-pathways and MAP kinase activation.
Topics: Blotting, Western; Cell Count; Cell Line, Tumor; Cell Movement; Choriocarcinoma; DNA Primers; Endothelin-1; Endothelin-3; Gene Expression; Genes, fos; Genes, jun; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Mitogen-Activated Protein Kinases; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: implications for therapy.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Apoptosis; Autocrine Communication; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chemokine CCL19; Chemokine CCL21; Cisplatin; Disease Models, Animal; Disease Progression; ErbB Receptors; Female; Formazans; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Paracrine Communication; Receptors, CCR7; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles; Up-Regulation | 2008 |
Synthesis and evaluation of antitumor activity of novel 2-[Nmethyl-N-(4-methyl-1,3-benzothiazol-2-yl)aminomethyl]-5,8-diacyloxy-1,4-naphthoquinones.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Leukemia L1210; Leukemia P388; Male; Mice; Mice, Inbred ICR; Naphthoquinones; Neoplasm Transplantation; Sarcoma 180; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Non-specific anti-proliferative effect of FTY720, a derivative of fungal metabolite from Iscaria sinclarii.
Topics: Aniline Compounds; Animals; Antibiotics, Antineoplastic; Cell Proliferation; Crotonates; Cyclosporine; Fingolimod Hydrochloride; Fungi; Hydroxybutyrates; Immunity, Cellular; Immunosuppressive Agents; Interleukin-2; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Nitriles; Propylene Glycols; Sphingosine; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Toluidines; Tumor Necrosis Factor-alpha | 2008 |
The effects of isoimperatorin isolated from Angelicae dahuricae on cyclooxygenase-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.
Topics: Angelica; Animals; Arachidonate 5-Lipoxygenase; Bone Marrow Cells; Butanols; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Electrophoresis, Polyacrylamide Gel; Furocoumarins; Hexosaminidases; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mast Cells; Mice; Mice, Inbred BALB C; Plant Extracts; Plant Roots; Prostaglandin D2; Solvents; Tetrazolium Salts; Thiazoles | 2008 |
Modulation of the genomic estrogen receptor pathway by water extracts of Cirsium japonicum.
Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Cirsium; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Indicators and Reagents; Luciferases; Plant Extracts; Plasmids; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Solvents; Tetrazolium Salts; Thiazoles; Transfection; Water | 2008 |
Apoptosis induced by (di-isopropyloxyphoryl-Trp)2-Lys-OCH3 in K562 and HeLa cells.
Topics: Annexins; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; G2 Phase; HeLa Cells; Humans; Inhibitory Concentration 50; K562 Cells; Mitosis; Molecular Structure; Oligopeptides; Phosphopeptides; S Phase; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
An alternative therapy for graves' disease: clinical effects and mechanisms of an herbal remedy.
Topics: Animals; Cell Line; Cell Proliferation; Cyclic AMP; DNA; Drugs, Chinese Herbal; Graves Disease; Humans; Iodide Peroxidase; Phytotherapy; Plant Extracts; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Thyroglobulin; Thyrotropin; Thyroxine | 2008 |
Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma.
Topics: Angelica; Antineoplastic Agents, Phytogenic; Apoptosis; Benzimidazoles; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chalcone; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Fluorescent Dyes; Humans; Neoplasm Proteins; Neuroblastoma; Plant Stems; Proteomics; Reactive Oxygen Species; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2008 |
A recombinant peptide, hirudin, potentiates the inhibitory effects of stealthy liposomal vinblastine on the growth and metastasis of melanoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Line, Tumor; Cell Movement; Drug Carriers; Drug Screening Assays, Antitumor; Drug Synergism; Extracellular Matrix Proteins; Hirudins; Homeostasis; Humans; Liposomes; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Particle Size; Protease Inhibitors; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Vinblastine | 2008 |
Decreased expression of phospholipase C-beta 1 protein in endoplasmic reticulum stress-loaded neurons.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Caspase 12; Caspase 3; Cell Survival; Cells, Cultured; Endoplasmic Reticulum; Enzyme Inhibitors; Neurons; Phospholipase C beta; Phospholipase C gamma; Rats; Stress, Physiological; Tetrazolium Salts; Thapsigargin; Thiazoles; Tunicamycin | 2008 |
Design, synthesis and anti flaviviridae activity of N(6)-, 5',3'-O- and 5',2'-O-substituted adenine nucleoside analogs.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Antiviral Agents; Cattle; CD4-Positive T-Lymphocytes; Cell Line; Chromatography, Thin Layer; Computer Simulation; Cricetinae; Diarrhea Viruses, Bovine Viral; Drug Design; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Entropy; Flaviviridae; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; RNA-Dependent RNA Polymerase; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Preparation of 1,8-di-O-alkylaloe-emodins and 15-amino-, 15-thiocyano-, and 15-selenocyanochrysophanol derivatives from aloe-emodin and studying their cytotoxic effects.
Topics: Aloe; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Organoselenium Compounds; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment; Tetrazolium Salts; Thiazoles | 2008 |
Cytotoxic constituents from Podocarpus fasciculus.
Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Chromatography, High Pressure Liquid; Diterpenes; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tracheophyta | 2008 |
Two new bis-coumarin glycosides from Daphne giraldii NITSCHE.
Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Coumarins; Daphne; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glycosides; Humans; Hydrolysis; Macrophages; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Plant Bark; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa).
Topics: Anti-Bacterial Agents; Cell Line, Tumor; Chromatography, Thin Layer; Colorimetry; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Medicine, African Traditional; Microbial Sensitivity Tests; Mycobacterium; Plant Extracts; Plants, Medicinal; South Africa; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2008 |
Toxic effects of recombinant tissue plasminogen activator on cultured human corneal endothelial cells.
Topics: Annexin A5; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Corneal; Flow Cytometry; Humans; Immunoenzyme Techniques; Membrane Proteins; Phosphoproteins; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tissue Plasminogen Activator; Zonula Occludens-1 Protein | 2008 |
Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3.
Topics: Cell Line, Tumor; Cell Proliferation; Culture Media, Serum-Free; Disease Progression; Dose-Response Relationship, Drug; Flow Cytometry; Galectin 3; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasm Invasiveness; Pancreas; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles | 2008 |
New 3D hyaluronan-based scaffold for in vitro reconstruction of the rat sciatic nerve.
Topics: Animals; Animals, Newborn; Biocompatible Materials; Bromodeoxyuridine; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelial Cells; Fibronectins; Gene Expression; Guided Tissue Regeneration; Humans; Hyaluronic Acid; In Vitro Techniques; Nerve Growth Factor; Nerve Regeneration; Platelet Endothelial Cell Adhesion Molecule-1; Rats; S100 Proteins; Schwann Cells; Sciatic Nerve; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Another multiheme protein, hydroxylamine oxidoreductase, abundantly produced in an anammox bacterium besides the hydrazine-oxidizing enzyme.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacteria, Anaerobic; Bacterial Proteins; Dimerization; Heme-Binding Proteins; Hemeproteins; Hydrazines; Methylphenazonium Methosulfate; Molecular Sequence Data; Oxidoreductases; Sewage; Substrate Specificity; Tetrazolium Salts; Thiazoles | 2008 |
Olfactory ensheathing cells promote proliferation and inhibit neuronal differentiation of neural progenitor cells through activation of Notch signaling.
Topics: Animals; Animals, Newborn; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Culture Media, Conditioned; Immunohistochemistry; Male; Neurons; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Stem Cells; Tetrazolium Salts; Thiazoles | 2008 |
Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins.
Topics: Anticholesteremic Agents; Caspases; Cell Line, Tumor; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscular Diseases; Quinolines; Tetrazolium Salts; Thiazoles | 2008 |
Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts.
Topics: Animals; Anthracenes; Arsenites; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Genistein; Heme Oxygenase-1; Mice; NF-E2-Related Factor 2; src-Family Kinases; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation | 2008 |
Effect of using RNA interference to alter iNOS gene expression on the proliferation of tongue squamous cell carcinoma cell line Tca8113.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Histocytochemistry; Humans; Indicators and Reagents; Lipids; Nitric Oxide; Nitric Oxide Synthase Type II; Plasmids; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Transfection | 2008 |
Arsenic interferes with the signaling transduction pathway of T cell receptor activation by increasing basal and induced phosphorylation of Lck and Fyn in spleen cells.
Topics: Animals; Apoptosis; Arsenic; Body Weight; CD28 Antigens; CD3 Complex; Cell Proliferation; Cell Survival; Cytokines; Drinking; Eating; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred C57BL; Monocytes; Necrosis; Phosphorylation; Proto-Oncogene Proteins c-fyn; Receptors, Antigen, T-Cell; Signal Transduction; Spleen; Tetrazolium Salts; Thiazoles | 2008 |
Troglitazone, a peroxisome proliferator-activated receptor gamma ligand, induces growth inhibition and apoptosis of HepG2 human liver cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Nucleus; Chromans; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Ligands; Models, Biological; PPAR gamma; Protein Transport; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2008 |
A red wine polyphenolic extract reduces the activation phenotype of cultured human liver myofibroblasts.
Topics: Actins; Cell Proliferation; Cell Survival; Cells, Cultured; DNA; Fibroblasts; Fibrosis; Flavonoids; Humans; Liver; Myofibrils; Phenols; Phenotype; Phosphorylation; Polyphenols; Tetrazolium Salts; Thiazoles; Wine | 2008 |
Effects of simulated carbon dioxide and helium peumoperitoneum on proliferation and apoptosis of gastric cancer cells.
Topics: Annexin A5; Apoptosis; Carbon Dioxide; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gases; Helium; Humans; Hydrogen-Ion Concentration; Pneumoperitoneum, Artificial; Pressure; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Enhanced expression of Harvey ras induced by serum deprivation in cultured astrocytes.
Topics: Analysis of Variance; Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Cycloheximide; Enzyme Inhibitors; Fluoresceins; Gene Expression Regulation; Mice; Oncogene Protein p21(ras); Protein Synthesis Inhibitors; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species.
Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Cell Line, Tumor; Enzyme Activation; HeLa Cells; HL-60 Cells; Humans; Inhibitory Concentration 50; Iron; K562 Cells; Membrane Potentials; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Activities of DNA-PK and Ku86, but not Ku70, may predict sensitivity to cisplatin in human gliomas.
Topics: Adult; Antigens, Nuclear; Antineoplastic Agents; Biological Assay; Biomarkers, Tumor; Brain Neoplasms; Cell Death; Cisplatin; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Glioma; Humans; Ku Autoantigen; Male; Middle Aged; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2008 |
Orthodontic adhesives induce human gingival fibroblast toxicity and inflammation.
Topics: Adhesives; Blotting, Western; Cell Survival; Cells, Cultured; Child; Colorimetry; Coloring Agents; Compomers; Cyclooxygenase 2; Dental Cements; Female; Fibroblasts; Gingiva; Gingivitis; Glass Ionomer Cements; Humans; Materials Testing; Orthodontic Appliances; Resin Cements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
WST-1-based cell cytotoxicity assay as a substitute for MTT-based assay for rapid detection of toxigenic Bacillus species using CHO cell line.
Topics: Animals; Bacillus; Bacterial Toxins; Bacteriological Techniques; CHO Cells; Cricetinae; Cricetulus; Food Microbiology; Tetrazolium Salts; Thiazoles | 2008 |
Traditional Chinese drug ShuXueTong facilitates angiogenesis during wound healing following traumatic brain injury.
Topics: Angiogenesis Modulating Agents; Animals; Brain Injuries; Capillaries; Drugs, Chinese Herbal; Endothelium, Vascular; Male; Medicine, Chinese Traditional; Motor Activity; Neovascularization, Physiologic; Paralysis; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Serum Response Factor; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A; Wound Healing | 2008 |
Microstructural characterization and comparative evaluation of physical, mechanical and biological properties of three ceramics for metal-ceramic restorations.
Topics: Aluminum Silicates; Apatites; Biocompatible Materials; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Porcelain; Dental Prosthesis Design; Differential Thermal Analysis; Elasticity; Fibroblasts; Glass; Hardness; Hot Temperature; Humans; Materials Testing; Metal Ceramic Alloys; Microscopy, Electron, Scanning; Periodontium; Potassium Compounds; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thermogravimetry; Thiazoles; X-Ray Diffraction | 2008 |
Neuroprotective activities of catalpol on MPP+/MPTP-induced neurotoxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glucosides; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase | 2008 |
Sodium salicylate switches glucose depletion-induced necrosis to autophagy and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents; Autophagy; Benzimidazoles; Cell Line, Tumor; Cyclooxygenase Inhibitors; Gene Expression Regulation, Neoplastic; Glucose; HMGB1 Protein; Humans; Lung Neoplasms; Necrosis; Sodium Salicylate; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2008 |
Testing the hypothesis that amphiphilic antineoplastic lipid analogues act through reduction of membrane curvature elastic stress.
Topics: Antineoplastic Agents; Cell Membrane; Choline-Phosphate Cytidylyltransferase; Elasticity; HL-60 Cells; Humans; Micelles; Molecular Structure; Neoplasms; Phospholipid Ethers; Stress, Mechanical; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Assessment of cell viability in primary neuronal cultures.
Topics: Animals; Cell Culture Techniques; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Colorimetry; Culture Media, Conditioned; Fluorescent Dyes; L-Lactate Dehydrogenase; Microscopy, Fluorescence; Mitochondria; Neurons; Preservation, Biological; Propidium; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trypan Blue | 2001 |
Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system.
Topics: Action Potentials; Animals; Antineoplastic Agents; Auditory Pathways; Bromodeoxyuridine; Cell Line, Tumor; Central Nervous System; Fluorouracil; Humans; In Situ Nick-End Labeling; Indoles; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Myelin Sheath; Rats; Stem Cells; Tetrazolium Salts; Thiazoles | 2008 |
Ginsenoside Rg1 protects neurons from hypoxic-ischemic injury possibly by inhibiting Ca2+ influx through NMDA receptors and L-type voltage-dependent Ca2+ channels.
Topics: Animals; Calcium; Calcium Channels, L-Type; Cell Survival; Dose-Response Relationship, Drug; Ginsenosides; Glucose; Hippocampus; Hormone Antagonists; Hypoxia-Ischemia, Brain; Immunohistochemistry; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mifepristone; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Thiazoles | 2008 |
Development of novel polymeric micellar drug conjugates and nano-containers with hydrolyzable core structure for doxorubicin delivery.
Topics: Animals; Antibiotics, Antineoplastic; Cell Survival; Chromatography, Gel; Doxorubicin; Drug Compounding; Drug Delivery Systems; Electrochemistry; Hydrolysis; Melanoma, Experimental; Mice; Micelles; Nanoparticles; Particle Size; Polyesters; Polymers; Tetrazolium Salts; Thiazoles | 2008 |
Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1'-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human hepatoma cells.
Topics: Animals; Anisoles; Biotransformation; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Repair; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Ocimum basilicum; Plant Extracts; Rats; Risk Assessment; Spectrometry, Mass, Electrospray Ionization; Subcellular Fractions; Sulfotransferases; Tetrazolium Salts; Thiazoles | 2008 |
Protective effect of trihexyphenidyl on hydrogen peroxide-induced oxidative damage in PC12 cells.
Topics: Animals; Antioxidants; Antiparkinson Agents; Apoptosis; Flow Cytometry; Fluorescent Dyes; Hydrogen Peroxide; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potentials; Mitochondrial Membranes; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Trihexyphenidyl; Vitamin E | 2008 |
In vitro activity of terpenes against Candida biofilms.
Topics: Biofilms; Candida; Candidiasis; Microbial Sensitivity Tests; Oils, Volatile; Terpenes; Tetrazolium Salts; Thiazoles | 2008 |
Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia.
Topics: Animals; Antidepressive Agents, Second-Generation; Cell Line; Cell Survival; Colforsin; Corticotropin-Releasing Hormone; Fluoxetine; Furocoumarins; Gene Expression Regulation; Mice; Promoter Regions, Genetic; Psoralea; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seeds; Tetrazolium Salts; Thiazoles | 2008 |
A comparative study of a range of polymeric microspheres as potential carriers for the inhalation of proteins.
Topics: Administration, Inhalation; Aerosols; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cytokines; Desiccation; Drug Carriers; Drug Stability; Excipients; Fluorescein; Fluorescent Dyes; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polymers; Proteins; Tetrazolium Salts; Thiazoles; Water | 2008 |
Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Berberine; Caspases; Cisplatin; Cytochromes c; DNA Fragmentation; Drug Synergism; Enzyme Activation; HeLa Cells; Humans; Indicators and Reagents; Lipid Peroxidation; Membrane Potentials; Mitochondria; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Preparation, characterization and in vitro anticancer activity of platinum(II) complexes with N-Cyclohexyl-1,3-propanediamine as the carrier.
Topics: Antineoplastic Agents; Cell Line, Tumor; Crystallography, X-Ray; Cyclohexylamines; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Indicators and Reagents; Molecular Conformation; Organoplatinum Compounds; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis and HIV-1 integrase inhibition activity of some N-arylindoles.
Topics: Cell Line; Cell Survival; Chromatography, Thin Layer; Giant Cells; HIV Integrase Inhibitors; HIV-1; Humans; Indicators and Reagents; Indoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Zinc adaptation and resistance to cadmium toxicity in mammalian cells: molecular insight by proteomic analysis.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Cadmium; Cadmium Poisoning; Carbonic Anhydrases; Cell Survival; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Epithelial Cells; HeLa Cells; Humans; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Zinc | 2008 |
Fluorescein diacetate for determination of cell viability in tissue-engineered skin.
Topics: Animals; Biopsy; Cell Survival; Collagen; Eosine Yellowish-(YS); Fluoresceins; Fluorescent Dyes; Glycosaminoglycans; Keratinocytes; Oxazines; Skin; Skin, Artificial; Tetrazolium Salts; Thiazoles; Tissue Engineering; Ultraviolet Rays; Xanthenes | 2008 |
Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Breast; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Flavonoids; Humans; Inhibitory Concentration 50; Tetrazolium Salts; Thiazoles | 2008 |
20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells.
Topics: Annexin A5; Apoptosis; Benzimidazoles; Blotting, Western; Caspase 3; Caspase 9; Chromatin; Coloring Agents; Culture Media, Serum-Free; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondrial Membranes; Myocytes, Smooth Muscle; Propidium; Proto-Oncogene Proteins c-bcl-2; Pulmonary Artery; Tetrazolium Salts; Thiazoles | 2008 |
Protective effects of 7-nitroindazole on ketamine-induced neurotoxicity in rat forebrain culture.
Topics: Analysis of Variance; Animals; Animals, Newborn; bcl-2-Associated X Protein; bcl-X Protein; Cell Survival; Cells, Cultured; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hydro-Lyases; Indazoles; Ketamine; Neural Cell Adhesion Molecule L1; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Prosencephalon; Rats; Sialic Acids; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.
Topics: Animals; Antiparkinson Agents; Apoptosis; Aromatic-L-Amino-Acid Decarboxylases; Blotting, Northern; Calcium; Carbolines; Cell Survival; Cyclic AMP; Dopamine; Flow Cytometry; Harmine; In Situ Nick-End Labeling; Levodopa; Membrane Potentials; Mitochondrial Membranes; PC12 Cells; Rats; RNA; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2008 |
Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line.
Topics: Animals; Apoptosis; Atrazine; Cell Proliferation; CHO Cells; Coloring Agents; Cricetinae; Cricetulus; Herbicides; Microscopy, Fluorescence; Necrosis; Neutral Red; Organic Chemicals; Tetrazolium Salts; Thiazoles; Trypan Blue | 2008 |
Dendroflorin retards the senescence of MRC-5 cells.
Topics: Cell Cycle; Cell Line; Cellular Senescence; Dendrobium; Flow Cytometry; Free Radical Scavengers; G1 Phase; Humans; Oxidative Stress; Reactive Oxygen Species; S Phase; Tetrazolium Salts; Thiazoles | 2008 |
Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells.
Topics: Animals; Annexin A5; Autophagy; Caspases; Cell Death; Cell Survival; Cells, Cultured; Enzyme Activation; Flow Cytometry; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Ketocholesterols; Microscopy, Electron, Transmission; Mitochondria, Muscle; Myocytes, Smooth Muscle; NAD; NADP; Neutral Red; Plasmids; Rabbits; Tetrazolium Salts; Thiazoles | 2008 |
Apoptosis of HeLa cells induced by cisplatin and its mechanism.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole; Cisplatin; Female; Flow Cytometry; Fluorescent Dyes; HeLa Cells; Humans; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Uterine Cervical Neoplasms | 2008 |
Effect of p27Kip1 inhibition on proliferation of bovine corneal endothelial cells by RNA interference.
Topics: Animals; Cattle; Cell Proliferation; Cornea; Cyclin-Dependent Kinase Inhibitor p27; Endothelial Cells; Gene Expression Regulation; Models, Biological; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Effect of exogenous bFGF on the proliferation of human adenoid cystic carcinoma ACC-2 cells.
Topics: Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Salivary Gland Neoplasms; Tetrazolium Salts; Thiazoles | 2008 |
Endogenous dopamine (DA) renders dopaminergic cells vulnerable to challenge of proteasome inhibitor MG132.
Topics: alpha-Methyltyrosine; Animals; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine; Leupeptins; Malondialdehyde; Mice; Neurodegenerative Diseases; Neurons; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Tetrazolium Salts; Thiazoles | 2008 |
Evaluation of RGD- or EGF-immobilized chitosan scaffolds for chondrogenic activity.
Topics: Analysis of Variance; Chitosan; Epidermal Growth Factor; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Oligopeptides; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2008 |
Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cells, Cultured; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Lasers; Male; Microdissection; Middle Aged; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2008 |
Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.
Topics: Animals; Cells, Cultured; Curcumin; Deferoxamine; Epithelial Cells; Ferric Compounds; Inhibitory Concentration 50; Liver; Oxidative Stress; Quaternary Ammonium Compounds; Rats; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Role of melatonin receptors in the effects of melatonin on BDNF and neuroprotection in mouse cerebellar neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebellum; Melatonin; Mice; Mice, Inbred C3H; Mice, Knockout; Neurons; Neuroprotective Agents; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2008 |
Predictive value of MTT assay as an in vitro chemosensitivity testing for gastric cancer: one institution's experience.
Topics: Aged; Antineoplastic Agents; Cell Survival; Coloring Agents; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Patient Compliance; Patient Selection; Predictive Value of Tests; Retrospective Studies; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome; Tumor Cells, Cultured | 2008 |
Sensitivity of different resistant tumour cell lines to the two novel compounds (2Z,4E)-2-methylsulfanyl-5-(1-naphthyl)-4-nitro-2,4-pentadienoate and (1E,3E)-1,4-bis(2-naphthyl)-2,3-dinitro-1,3-butadiene.
Topics: Antineoplastic Agents; Butadienes; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Fatty Acids, Unsaturated; Fluorescent Antibody Technique; Humans; Microtubules; Naphthalenes; Tetrazolium Salts; Thiazoles | 2008 |
Isoflurane preconditioning reduces mouse microglial activation and injury induced by lipopolysaccharide and interferon-gamma.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Blotting, Western; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glutamic Acid; Guanidines; Interferon-gamma; Isoflurane; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase Type II; Nitrites; Protein Kinase C; Tetrazolium Salts; Thiazoles | 2008 |
Investigation of rifampicin-induced hepatotoxicity in rat hepatocytes maintained in gel entrapment culture.
Topics: Acetylcysteine; Albumins; Animals; Antitubercular Agents; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Drug Antagonism; Enzyme Inhibitors; Glutathione; Glycyrrhizic Acid; Hepatocytes; Lipid Metabolism; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rifampin; Tetrazolium Salts; Thiazoles | 2009 |
Anti-inflammatory effects of catechols in lipopolysaccharide-stimulated microglia cells: inhibition of microglial neurotoxicity.
Topics: Anti-Inflammatory Agents; Blotting, Western; Catechols; Cell Survival; Coculture Techniques; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Lipopolysaccharides; Microglia; Neurotoxicity Syndromes; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity.
Topics: Animals; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Calpain; Caspase 3; Cell Line, Tumor; Chymotrypsin; Copper; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Situ Nick-End Labeling; Kinetics; Proteasome Inhibitors; Pyrrolidines; Rabbits; Tetrazolium Salts; Thiazoles; Thiocarbamates; Time Factors; Zinc | 2008 |
Targeting of efavirenz loaded tuftsin conjugated poly(propyleneimine) dendrimers to HIV infected macrophages in vitro.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cell Survival; Cells, Cultured; Cyclopropanes; Dendrimers; Drug Delivery Systems; HIV Infections; Humans; Macrophages; Magnetic Resonance Spectroscopy; Monocytes; Phagocytosis; Polypropylenes; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Tuftsin | 2008 |
cAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons.
Topics: Adenine; Animals; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Motor Neurons; Neurites; Pregnancy; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetrazolium Salts; Thiazoles | 2008 |
Characterisation and controlled drug release from novel drug-loaded hydrogels.
Topics: Acrylamides; Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cell Survival; Cells, Cultured; Cross-Linking Reagents; Delayed-Action Preparations; Diclofenac; Humans; Hydrogels; Polymers; Povidone; Procaine; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2008 |
Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2).
Topics: Apoptosis; Biphenyl Compounds; Blotting, Western; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Imidazoles; Lignans; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Cell death and neuronal arborization upon quercetin treatment in rat neurons.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Neurons; Propidium; Quercetin; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2008 |
A functionally significant cross-talk between androgen receptor and ErbB2 pathways in estrogen receptor negative breast cancer.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Humans; Models, Biological; Phosphorylation; Receptor, ErbB-2; Receptors, Androgen; Receptors, Estrogen; Tetrazolium Salts; Thiazoles | 2008 |
Mechanical and in vitro performance of 13-93 bioactive glass scaffolds prepared by a polymer foam replication technique.
Topics: 3T3 Cells; Animals; Bone and Bones; Bone Regeneration; Cell Adhesion; Glass; Humans; Mice; Microscopy, Electron, Scanning; Osteoblasts; Polymers; Porosity; Pressure; Stress, Mechanical; Tetrazolium Salts; Thiazoles | 2008 |
Apoptosis-inducing effects of two anthraquinones from Hedyotis diffusa WILLD.
Topics: Annexin A5; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Bisbenzimidazole; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hedyotis; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Potentials; Mitochondrial Membranes; Prohibitins; Rhodamine 123; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; src-Family Kinases; Tetrazolium Salts; Thiazoles | 2008 |
BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells.
Topics: Actins; Amino Acid Transport Systems; Amino Acids, Cyclic; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspases; Cell Division; Cell Line, Tumor; DNA Fragmentation; Enzyme Activation; Humans; In Situ Nick-End Labeling; KB Cells; Large Neutral Amino Acid-Transporter 1; Leucine; Tetrazolium Salts; Thiazoles | 2008 |
Preventive effects of a Kampo medicine, Shosaikoto, on inflammatory responses in LPS-treated human gingival fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gingiva; Gingivitis; Humans; Indicators and Reagents; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Medicine, Kampo; Monocytes; Porphyromonas gingivalis; Tetrazolium Salts; Thiazoles | 2008 |
Reversal of P-glycoprotein and multidrug resistance-associated protein 1 mediated multidrug resistance in cancer cells by HZ08 Isomers, tetrataisohydroquinolin derivatives.
Topics: Annexin A5; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescein-5-isothiocyanate; Glutathione; Glutathione Transferase; Humans; Isoquinolines; K562 Cells; Rhodamine 123; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles | 2008 |
Design, synthesis and cytotoxicity of novel podophyllotoxin derivatives.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorimetry; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Podophyllotoxin; Rhodamines; Tetrazolium Salts; Thiazoles; Tubulin | 2008 |
Triterpenoidal saponins from the barks of Zygophyllum fabago L.
Topics: Animals; Cell Line; Hydrolysis; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; Nitric Oxide; Plant Bark; Plant Extracts; Saponins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Triterpenes; Zygophyllum | 2008 |
(-)-Anonaine induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Aporphines; bcl-2-Associated X Protein; Caspases; Cell Cycle; Cell Line, Tumor; Dioxoles; Flow Cytometry; Glutathione; HeLa Cells; Humans; In Situ Nick-End Labeling; Membrane Potentials; Mitochondrial Membranes; Nitric Oxide; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Domoic acid induced spinal cord lesions in adult mice: evidence for the possible molecular pathways of excitatory amino acids in spinal cord lesions.
Topics: Animals; Cell Death; Cell Line, Transformed; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Female; In Situ Nick-End Labeling; Kainic Acid; Mice; Mice, Inbred C57BL; Movement Disorders; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Severity of Illness Index; Signal Transduction; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles | 2008 |
Macrophage inflammatory protein-3alpha influences growth of K562 leukemia cells in co-culture with anticancer drug-pretreated HS-5 stromal cells.
Topics: Antineoplastic Agents; Blotting, Western; Cell Proliferation; Cell Survival; Chemokine CCL20; Coculture Techniques; Culture Media, Conditioned; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; K562 Cells; Stromal Cells; Tetrazolium Salts; Thiazoles | 2008 |
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.
Topics: Amides; Aniline Compounds; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzimidazoles; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; Glutathione Transferase; Hippocampus; Microtubule-Associated Proteins; Neurites; Neurons; Neuroprotective Agents; Pregnancy; Pyridines; Rats; rhoA GTP-Binding Protein; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Neurotoxicity of cadmium on immature hippocampus and a neuroprotective role for p38 MAPK.
Topics: Animals; Animals, Newborn; Cadmium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Hippocampus; Imidazoles; In Vitro Techniques; Male; Neurotoxins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Mechanisms of chromium (VI)-induced apoptosis in anterior pituitary cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspases; Catalase; Cells, Cultured; Chromium; DNA Primers; Male; Oxidative Stress; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2008 |
The immobilization of animal cells using the cysteine-modified RGD oligopeptide.
Topics: Amino Acid Sequence; Animals; Cell Division; Cell Survival; Cells; Cells, Immobilized; Cysteine; HeLa Cells; Humans; Image Processing, Computer-Assisted; Microscopy; Microscopy, Atomic Force; Oligopeptides; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis of azaisoflavones and their inhibitory activities of NO production in activated microglia.
Topics: Animals; Cell Line; Chemistry, Pharmaceutical; Drug Design; Inhibitory Concentration 50; Isoflavones; Mice; Microglia; Models, Chemical; Nitric Oxide; Nitric Oxide Synthase Type II; Quinolones; Temperature; Tetrazolium Salts; Thiazoles | 2008 |
Evaluation of tumour promoting potency of fish borne toxaphene residues, as compared to technical toxaphene and UV-irradiated toxaphene.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carcinogens; Cell Communication; Gadus morhua; Gap Junctions; Glutathione Peroxidase; Insecticides; Liver; Liver Neoplasms; Meat; Organ Size; Pesticide Residues; Rats; Tetrazolium Salts; Thiazoles; Thymus Gland; Toxaphene; Ultraviolet Rays | 2008 |
HBV X gene transfection upregulates IL-1beta and IL-6 gene expression and induces rat glomerular mesangial cell proliferation.
Topics: Animals; Cell Proliferation; Gene Expression Regulation, Viral; Glomerular Mesangium; Inflammation; Interleukin-1beta; Interleukin-6; Mesangial Cells; Plasmids; Rats; Tetrazolium Salts; Thiazoles; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Viral Regulatory and Accessory Proteins | 2008 |
Synthetic Smac peptide enhances chemo-sensitivity of bladder cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Models, Biological; Peptides; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Time Factors; Urinary Bladder Neoplasms; X-Linked Inhibitor of Apoptosis Protein | 2008 |
Induction of SiHa cells apoptosis by nanometer realgar suspension and its mechanism.
Topics: Apoptosis; Arsenicals; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Electron, Transmission; Nanotechnology; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Repressor Proteins; Sulfides; Tetrazolium Salts; Thiazoles; Time Factors; Uterine Cervical Neoplasms | 2008 |
Immune killing activity of lymphocytes on Hela cells expressing interleukin-12 in vitro.
Topics: Apoptosis; Cell Survival; Coculture Techniques; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Immune System; Interleukin-12; Killer Cells, Natural; Lymphocytes; T-Lymphocytes, Cytotoxic; Tetrazolium Salts; Thiazoles; Time Factors; Uterine Cervical Neoplasms | 2008 |
Effects of lutein on the growth and migration of bovine lens epithelial cells in vitro.
Topics: Animals; Cataract; Cattle; Cell Movement; Cell Proliferation; Cells, Cultured; Epithelial Cells; In Vitro Techniques; Lens, Crystalline; Lutein; Tetrazolium Salts; Thiazoles; Time Factors; Wound Healing | 2008 |
The active metabolite of leflunomide A771726 inhibits corneal neovascularization.
Topics: Aniline Compounds; Animals; Cell Nucleus; Cell Proliferation; Corneal Neovascularization; Crotonates; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Hydroxybutyrates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Nitriles; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors; Toluidines; Umbilical Veins | 2008 |
Effect of quercetin on proliferation and apoptosis of human nasopharyngeal carcinoma HEN1 cells.
Topics: Antioxidants; Apoptosis; Carcinoma; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Nasopharyngeal Neoplasms; Necrosis; Quercetin; Tetrazolium Salts; Thiazoles | 2008 |
Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering.
Topics: Cells, Cultured; Chitosan; Coculture Techniques; DNA; Genes, Reporter; Humans; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Periodontal Ligament; Plasmids; Platelet-Derived Growth Factor; Porosity; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2009 |
Human antimicrobial peptides' antifungal activity against Aspergillus fumigatus.
Topics: Amphotericin B; Animals; Antifungal Agents; Antimicrobial Cationic Peptides; Aspergillosis; Aspergillus fumigatus; Erythrocytes; Hemolysis; Humans; Hyphae; Mice; Microbial Sensitivity Tests; Microbial Viability; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2008 |
Parthenolide inhibits proliferation of fibroblast-like synoviocytes in vitro.
Topics: Animals; Arthritis, Rheumatoid; Bromodeoxyuridine; Cell Line; Cell Proliferation; Fibroblasts; Humans; Hyperplasia; Phytotherapy; Rabbits; Sesquiterpenes; Synovial Membrane; Tanacetum parthenium; Tetrazolium Salts; Thiazoles | 2008 |
Peroxisome proliferator-activated receptor-gamma and retinoid X receptor agonists synergistically suppress proliferation of immortalized endometrial stromal cells.
Topics: Cell Division; Cell Line; Endometrium; Estradiol; Female; Humans; Nicotinic Acids; PPAR gamma; Progesterone; Retinoid X Receptors; Stromal Cells; Tetrahydronaphthalenes; Tetrazolium Salts; Thiazoles; Thiazolidinediones | 2009 |
Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo.
Topics: Administration, Oral; Aged; Animals; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Nude; Middle Aged; Nitrobenzenes; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Pyrazoles; Radioligand Assay; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2008 |
Chronic treatment with electroconvulsive shock may modulate the immune function of macrophages.
Topics: Animals; Arginase; Cell Adhesion; Cell Survival; Electroshock; Immunity, Cellular; Lipopolysaccharides; Macrophages, Peritoneal; Male; Nitric Oxide; Nitroblue Tetrazolium; Oxazines; Pinocytosis; Rats; Tetrazolium Salts; Thiazoles; Xanthenes | 2008 |
Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Metals; PC12 Cells; Rats; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Gallic acid-based indanone derivatives as anticancer agents.
Topics: Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Erythrocytes; Gallic Acid; Hemolysis; Humans; Indans; Inhibitory Concentration 50; Models, Chemical; Osmosis; Tetrazolium Salts; Thiazoles | 2008 |
Pyrroloquinoline quinone prevents oxidative stress-induced neuronal death probably through changes in oxidative status of DJ-1.
Topics: Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Microtubule-Associated Proteins; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxidopamine; Pregnancy; Protein Binding; Protein Deglycase DJ-1; Pyrroles; Quinolines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E | 2008 |
Inhibitory effects of salvianolic acid B on the high glucose-induced mesangial proliferation via NF-kappaB-dependent pathway.
Topics: Antioxidants; Benzofurans; Blotting, Western; Cell Cycle; Cell Nucleus; Cell Proliferation; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fibronectins; Flow Cytometry; Glucose; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesangial Cells; NF-kappa B; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Amiodarone increases the accumulation of DEA in a human alveolar epithelium-derived cell line.
Topics: Adenosine Triphosphate; Amiodarone; Anti-Arrhythmia Agents; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Epithelial Cells; Humans; Pulmonary Alveoli; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
The herb medicine formula "Yang Wei Kang Liu" improves the survival of late stage gastric cancer patients and induces the apoptosis of human gastric cancer cell line through Fas/Fas ligand and Bax/Bcl-2 pathways.
Topics: Acridine Orange; Animals; Antigens, Nuclear; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Drugs, Chinese Herbal; Fas Ligand Protein; Flow Cytometry; Humans; Karnofsky Performance Status; Membrane Potentials; Mitochondrial Membranes; Proto-Oncogene Proteins c-bcl-2; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Survival; Tetrazolium Salts; Thiazoles | 2008 |
Antimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites.
Topics: Anti-Infective Agents; Anticoagulants; Bacteria; Escherichia coli; Gastrointestinal Tract; Heparin; Humans; Microbial Sensitivity Tests; Mouth; Neuropeptides; Respiratory System; Skin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles | 2008 |
Eupatilin inhibits H(2)O(2)-induced apoptotic cell death through inhibition of mitogen-activated protein kinases and nuclear factor-kappaB.
Topics: Apoptosis; Artemisia; Blotting, Western; Caspase 3; Cell Line; Electrophoretic Mobility Shift Assay; Epithelial Cells; Flavonoids; Flow Cytometry; Gastric Mucosa; Humans; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Necrosis; NF-kappa B; Nuclear Proteins; Oxidants; Tetrazolium Salts; Thiazoles | 2008 |
Functional hepatocyte-like cells derived from human bone marrow mesenchymal stem cells on a novel 3-dimensional biocompatible nanofibrous scaffold.
Topics: Alanine Transaminase; Albumins; Biocompatible Materials; Biomarkers; Cell Differentiation; Cells, Cultured; Flow Cytometry; Hepatocytes; Humans; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Nanotechnology; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Transferrin; Urea | 2008 |
Isolation and biological analysis of tumor stem cells from pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; CD24 Antigen; Cell Line, Tumor; Cell Proliferation; Cell Separation; Flow Cytometry; Humans; Hyaluronan Receptors; Male; Mice; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 2008 |
Structure-activity relationships for hepatocyte toxicity and electrophilic reactivity of alpha,beta-unsaturated esters, acrylates and methacrylates.
Topics: Acrylates; Animals; Butylamines; Chemistry, Physical; Esters; Glutathione; Hepatocytes; Male; Methacrylates; Models, Molecular; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Regression Analysis; Solubility; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
Increasing cell adhesion on plasma deposited fluorocarbon coatings by changing the surface topography.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Carbon; Cell Adhesion; Cell Membrane; Colloids; Extracellular Matrix; Fluorine; Fluorocarbons; Humans; Mice; Microscopy, Electron, Scanning; Surface Properties; Tetrazolium Salts; Thiazoles | 2009 |
Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.
Topics: Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebellum; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Interactions; Fatty Acids; Fluoresceins; Glutathione; Methylmercury Compounds; Mice; Neurons; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Neural differentiation arrest in embryonal carcinoma cells with forced expression of EWS-FLI1.
Topics: Animals; Apoptosis; Carcinoma, Embryonal; Cell Cycle; Cell Differentiation; Cell Proliferation; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Humans; Mice; Nerve Tissue Proteins; Neurons; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tretinoin | 2008 |
Cytotoxicity of oxidised lipids in cultured colonal human intestinal cancer cells (caco-2 cells).
Topics: Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Blotting, Western; Caco-2 Cells; Caspase 3; Catechin; Coloring Agents; DNA, Neoplasm; Fish Oils; Fluorescent Antibody Technique; Humans; Linoleic Acid; Lipid Peroxidation; Lipids; Oxidation-Reduction; Tea; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays | 2008 |
Application of structure-activity relationships to investigate the molecular mechanisms of hepatocyte toxicity and electrophilic reactivity of alpha,beta-unsaturated aldehydes.
Topics: Aldehyde Dehydrogenase; Aldehydes; Algorithms; Animals; Butylamines; Cell Survival; Glutathione; Hepatocytes; Male; Models, Molecular; Models, Statistical; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Regression Analysis; Tetrazolium Salts; Thiazoles | 2008 |
The expression and role of stromal cell-derived factor-1alpha-CXCR4 axis in human dental pulp.
Topics: Adolescent; Adult; Adult Stem Cells; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CXCL12; Dental Pulp; Dentin, Secondary; Humans; Immunohistochemistry; Pulpitis; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2008 |
Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications.
Topics: alpha-Amylases; Animals; Biocompatible Materials; Bone and Bones; Cell Adhesion; Cell Proliferation; Chitosan; Compressive Strength; Humans; Mice; Microscopy, Electron, Scanning; Muramidase; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2008 |
Effects of lactone derivatives on aromatase (CYP19) activity in H295R human adrenocortical and (anti)androgenicity in transfected LNCaP human prostate cancer cells.
Topics: Adrenal Cortex Neoplasms; Androgen Receptor Antagonists; Androgens; Aromatase Inhibitors; Cell Line, Tumor; Cyclic AMP; Data Interpretation, Statistical; Genes, Reporter; Humans; Lactones; Luciferases; Male; Prostatic Neoplasms; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
The in vitro biological activity of selected South African Commiphora species.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Commiphora; Drug Screening Assays, Antitumor; Free Radical Scavengers; Humans; Lipoxygenase Inhibitors; Microbial Sensitivity Tests; Picrates; Plant Bark; Plant Extracts; Plant Leaves; South Africa; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Diterpenes, Kaurane; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; HL-60 Cells; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2008 |
In vitro cytotoxicity of different desensitizers under simulated pulpal flow conditions.
Topics: Animals; Cattle; Cell Line; Coloring Agents; Dental Pulp; Dentin Sensitivity; Dentin-Bonding Agents; Fibroblasts; Glutaral; Hydrogen Peroxide; Materials Testing; Methacrylates; Mice; Oxidants; Perfusion; Resin Cements; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Dexamethasone reduced invasiveness of human malignant glioblastoma cells through a MAPK phosphatase-1 (MKP-1) dependent mechanism.
Topics: Antineoplastic Agents, Hormonal; Blotting, Western; Cell Line, Tumor; Chorioallantoic Membrane; Collagen; Dexamethasone; Drug Combinations; Dual Specificity Phosphatase 1; Glioblastoma; Humans; Immunohistochemistry; Laminin; Mitogen-Activated Protein Kinase 1; Neoplasm Invasiveness; Nitric Oxide; Nitric Oxide Synthase Type II; Plasmids; Proteoglycans; Tetrazolium Salts; Thiazoles | 2008 |
Naringenin-7-O-glucoside protects against doxorubicin-induced toxicity in H9c2 cardiomyocytes by induction of endogenous antioxidant enzymes.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Blotting, Western; Cell Nucleus; Cells, Cultured; Cytosol; Doxorubicin; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Flavanones; Glucosides; Glutathione; Malondialdehyde; Myocytes, Cardiac; Phosphorylation; Protein Transport; Quercetin; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2008 |
Liposome encapsulation reduces cantharidin toxicity.
Topics: Animals; Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Electrochemistry; Female; Humans; Hyperbaric Oxygenation; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Octreotide; Particle Size; Tetrazolium Salts; Thiazoles | 2008 |
SAR study of a novel triene-ansamycin group compound, quinotrierixin, and related compounds, as inhibitors of ER stress-induced XBP1 activation.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry, Physical; DNA-Binding Proteins; HeLa Cells; Humans; Luciferases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Rifabutin; Streptomyces; Stress, Physiological; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Transcription Factors; X-Box Binding Protein 1 | 2008 |
Blockade of anaesthetic-induced preconditioning in the hyperglycaemic myocardium: the regulation of different mitogen-activated protein kinases.
Topics: Anesthetics; Anesthetics, Inhalation; Animals; Blood Glucose; Blood Pressure; Blotting, Western; Desflurane; Electrocardiography; Gene Expression Regulation, Enzymologic; Heart Rate; Hyperglycemia; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2008 |
Disruption of LH-induced testosterone biosynthesis in testicular Leydig cells by triclosan: probable mechanism of action.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); Adenylyl Cyclases; Animals; Anti-Infective Agents, Local; Blotting, Western; Cell Separation; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic AMP; Dose-Response Relationship, Drug; Endocrine Disruptors; Leydig Cells; Luteinizing Hormone; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Tetrazolium Salts; Thiazoles; Triclosan | 2008 |
Increased apoptosis in HepG2.2.15 cells with hepatitis B virus expression by synergistic induction of interferon-gamma and tumour necrosis factor-alpha.
Topics: Apoptosis; Cell Line, Tumor; Gene Expression Profiling; Hepatitis B virus; Hepatocytes; Humans; Interferon-gamma; Oligonucleotide Array Sequence Analysis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2009 |
Effects of rosiglitazone on the proliferation of vascular smooth muscle cell induced by high glucose.
Topics: Animals; Aorta, Thoracic; Cattle; Cell Count; Cell Proliferation; Cells, Cultured; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Flow Cytometry; Glucose; Hypoglycemic Agents; Male; Mannose; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; S Phase; Skin; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Trypan Blue; Wound Healing | 2008 |
Neuroprotective effects of Yi-Gan San against beta amyloid-induced cytotoxicity on rat cortical neurons.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Embryo, Mammalian; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Tetrazolium Salts; Thiazoles | 2008 |
Attachment, proliferation and osteogenic response of osteoblast-like cells cultured on titanium treated by a novel multiphase anodic spark deposition process.
Topics: Alkaline Phosphatase; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Electrochemistry; Humans; Integrin-Binding Sialoprotein; Microscopy, Electron, Scanning; Osteoblasts; Osteopontin; Sialoglycoproteins; Surface Properties; Temperature; Tetrazolium Salts; Thiazoles; Titanium | 2009 |
Cell density-dependent alterations in tumorigenic potential of a murine T-cell lymphoma: implication in the evolution of multidrug resistance in tumor cells.
Topics: Animals; Ascitic Fluid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Count; Cytokines; Disease Progression; DNA Fragmentation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Indicators and Reagents; Lymphoma, T-Cell; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2008 |
9-nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; Injections, Intravenous; Lactones; Male; Nanoparticles; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2008 |
Accurate assessment of the bioactivities of redox-active polyphenolics in cell culture.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Flavonoids; Leukocytes, Mononuclear; Lipopolysaccharides; Oxidation-Reduction; Phenols; Polyphenols; Rabbits; Tannins; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Differentiation; Cell Survival; Cyclin-Dependent Kinase 3; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glucocorticoids; Green Fluorescent Proteins; Humans; Neurons; PC12 Cells; Phosphorylation; Rats; Signal Transduction; tau Proteins; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Impairment of mitochondrial energy metabolism in different regions of rat brain following chronic exposure to aluminium.
Topics: Adenosine Triphosphate; Aluminum; Animals; Brain Chemistry; Cytochromes; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Glutathione; Male; Microscopy, Electron; Mitochondria; NADH Dehydrogenase; Oxidative Phosphorylation; Phosphates; Rats; Rats, Wistar; Reactive Oxygen Species; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2008 |
Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Primers; Gene Expression Regulation, Neoplastic; Heme Oxygenase (Decyclizing); Hepacivirus; Humans; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Silymarin; Tetrazolium Salts; Thiazoles | 2009 |
Ginsenoside Rg1 attenuates beta-amyloid-induced apoptosis in mutant PS1 M146L cells.
Topics: Amyloid beta-Peptides; Animals; Annexin A5; Apoptosis; Caspase 3; Cell Survival; Central Nervous System Agents; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Flow Cytometry; Ginsenosides; In Situ Nick-End Labeling; Leucine; Methionine; Mutation; Peptide Fragments; Presenilin-1; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Acivicin with glutaminase regulates proliferation and invasion of human MCF-7 and OAW-42 cells--an in vitro study.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Combinations; Female; Glutaminase; Glutamine; Humans; In Vitro Techniques; Isoxazoles; Laminin; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Ovarian Neoplasms; Proteoglycans; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2008 |
Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells.
Topics: 3T3 Cells; Acanthaceae; Alkaline Phosphatase; Animals; Bone Density Conservation Agents; Calcium; Cell Differentiation; Chemical Phenomena; Chemistry, Physical; Collagen; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Conformation; Osteoblasts; Plant Extracts; Plant Leaves; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2008 |
Preparation and gene delivery of alkaline amino acids-based cationic liposomes.
Topics: Amino Acids; Arginine; Cations; Cell Line; Cholesterol; Deoxyribonuclease I; Drug Carriers; Electrophoresis, Agar Gel; Gene Transfer Techniques; Genes, Reporter; Histidine; Humans; Light; Liposomes; Luciferases; Lysine; Microscopy, Electron, Transmission; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Antioxidant effects of equol on bovine aortic endothelial cells.
Topics: Animals; Antioxidants; Aorta; Apoptosis; Cattle; Cytoprotection; Endothelium, Vascular; Equol; Hydrogen Peroxide; Imidazoles; Isoflavones; p38 Mitogen-Activated Protein Kinases; Phytoestrogens; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Lysophosphatidylcholine protects cerebellar granule neurons from apoptotic cell death.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbon Isotopes; Cell Survival; Cells, Cultured; Cerebellum; Choline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lysophosphatidylcholines; Lysophospholipids; Mice; Neurons; Neuroprotective Agents; Nicardipine; Potassium; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Globins; Glutathione; Hyperbaric Oxygenation; Hypoxia; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Nerve Tissue Proteins; Neuroglobin; Neurons; Oxidative Stress; Phenanthridines; Tetrazolium Salts; Thiazoles | 2009 |
Spontaneous formation of bilayers and vesicles in mixtures of single-chain alkyl carboxylates: effect of pH and aging and cytotoxicity studies.
Topics: Biocompatible Materials; Carboxylic Acids; Cryoelectron Microscopy; HeLa Cells; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Lauric Acids; Light; Lipid Bilayers; Microscopy, Electron, Transmission; Phase Transition; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
A new method to induce multi-drug resistance to carboplatin in a mouse model of human tongue squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Coloring Agents; Disease Models, Animal; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione Transferase; Humans; Immunohistochemistry; Injections, Intradermal; Mice; Mice, Inbred BALB C; Mice, Nude; Multidrug Resistance-Associated Proteins; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Transplantation, Heterologous; Tumor Cells, Cultured | 2008 |
A novel anti-cancer effect of genistein: reversal of epithelial mesenchymal transition in prostate cancer cells.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epithelial Cells; Genistein; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2008 |
Preliminary evaluation of the toxicity of some synthetic furan derivatives in two cell lines and Artemia salina.
Topics: Animals; Artemia; Biological Assay; Cell Line, Tumor; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Furans; Humans; Mesocricetus; Quantitative Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2009 |
Evaluation of toxicity of commercial ophthalmic fluoroquinolone antibiotics as assessed on immortalized corneal and conjunctival epithelial cells.
Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Cell Survival; Ciprofloxacin; Conjunctiva; Drug Evaluation, Preclinical; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Tetrazolium Salts; Thiazoles | 2008 |
Antioxidants prevent the cytotoxicity of manganese in RBE4 cells.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Cell Line, Transformed; Cell Survival; Chlorides; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Glutathione; L-Lactate Dehydrogenase; Manganese Compounds; Rats; Sulfates; Tetrazolium Salts; Thiazoles | 2008 |
Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzofurans; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cell Survival; Crystallography, X-Ray; DNA, Complementary; Dogs; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluoresceins; Humans; Indicators and Reagents; Mitoxantrone; Models, Molecular; Neoplasm Proteins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2008 |
Evaluation of the antiproliferative activity of 2-(monohalogenophenylamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Hydrocarbons, Halogenated; Tetrazolium Salts; Thiadiazoles; Thiazoles | 2008 |
Cytotoxicity effects induced by Zearalenone metabolites, alpha Zearalenol and beta Zearalenol, on cultured Vero cells.
Topics: Animals; Cell Survival; Chlorocebus aethiops; DNA; Estrogens, Non-Steroidal; Heat-Shock Proteins; Leucine; Lipid Peroxidation; Malondialdehyde; Tetrazolium Salts; Thiazoles; Thymidine; Vero Cells; Zearalenone; Zeranol | 2008 |
Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition.
Topics: Animals; Cell Survival; Cells, Cultured; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fibroblasts; Glutathione; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Mutagens; Nanoparticles; Nanotubes, Carbon; Oxidative Stress; Particle Size; Reactive Oxygen Species; Silicon Dioxide; Soot; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Zinc Oxide | 2009 |
Proteome profiling of U2OS cell line in response to a prenylphenol antibiotic isolated from a phytopathogenic fungus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Ascomycota; Blotting, Western; Cell Line; Cell Line, Tumor; Databases, Protein; Electrophoresis, Gel, Two-Dimensional; Gelatin; Humans; Hydrolysis; Image Processing, Computer-Assisted; Indicators and Reagents; Molecular Sequence Data; Proteome; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Trypsin | 2008 |
Preparation of propolis nanofood and application to human cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Chemistry, Physical; Drug Compounding; Humans; Kinetics; Light; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Nanoparticles; Pancreatic Neoplasms; Polymers; Propolis; Scattering, Radiation; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2008 |
Protective effects of sanjoinine A against N-methyl-D-aspartate-induced seizure.
Topics: Animals; Anticonvulsants; Calcium; Cell Survival; Cells, Cultured; Electroencephalography; Electroshock; Excitatory Amino Acid Agonists; Female; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Seizures; Tetrazolium Salts; Thiazoles; Ziziphus | 2008 |
Anti-metastatic potential of ginsenoside Rp1, a novel ginsenoside derivative.
Topics: Animals; Antineoplastic Agents, Phytogenic; Capillaries; Cell Adhesion; Cell Line, Tumor; Flow Cytometry; Ginsenosides; Humans; Injections, Intravenous; Integrin beta1; Male; Matrix Metalloproteinase 2; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Panax; Tetrazolium Salts; Thiazoles | 2008 |
Junceols D-H, new polyoxygenated briaranes from sea whip gorgonian coral Junceella juncea (Ellisellidae).
Topics: Animals; Anthozoa; Antioxidants; Cell Survival; Heterocyclic Compounds, 3-Ring; Humans; Lactones; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Neutrophils; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Superoxides; Tetrazolium Salts; Thiazoles | 2008 |
Benzaldehyde derivatives from Eurotium rubrum, an endophytic fungus derived from the mangrove plant Hibiscus tiliaceus.
Topics: Animals; Antibiotics, Antineoplastic; Ascomycota; Benzaldehydes; Cell Line, Tumor; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Fermentation; Hibiscus; Humans; Magnetic Resonance Spectroscopy; Mice; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2008 |
Effects of a hindered amine light stabilizer and a UV light absorber used in maxillofacial elastomers on human gingival epithelial cells and fibroblasts.
Topics: Cell Line; Cell Membrane; Cell Proliferation; Cell Survival; Colorimetry; Coloring Agents; Decanoic Acids; Epithelial Cells; Fibroblasts; Gingiva; Humans; L-Lactate Dehydrogenase; Materials Testing; Maxillofacial Prosthesis; Piperidines; Silicone Elastomers; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors; Triazoles | 2008 |
Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glucuronidase; Humans; Insulin; Insulin-Like Growth Factor I; Ki-67 Antigen; Klotho Proteins; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tissue Array Analysis | 2008 |
Toothpaste detergents: a potential source of oral soft tissue damage?
Topics: Betaine; Cell Death; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Coloring Agents; Detergents; Humans; Keratinocytes; Mouth Mucosa; Poloxamer; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Time Factors; Toothpastes | 2008 |
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Boronic Acids; Bortezomib; Brain Neoplasms; Carboplatin; Carmustine; Cell Line, Tumor; Dacarbazine; Dose-Response Relationship, Drug; ErbB Receptors; Flow Cytometry; Gefitinib; Glial Fibrillary Acidic Protein; Glioblastoma; Immunohistochemistry; Indicators and Reagents; Mice; Proteasome Inhibitors; Pyrazines; Quinazolines; Rats; Temozolomide; Tetrazolium Salts; Thiazoles | 2008 |
Embryotoxicity hazard assessment of cadmium and arsenic compounds using embryonic stem cells.
Topics: Algorithms; Animals; Arsenic; Arsenicals; BALB 3T3 Cells; Cadmium; Cell Differentiation; Embryonic Stem Cells; Endpoint Determination; Female; Methylmercury Compounds; Mice; Myocytes, Cardiac; Pregnancy; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2008 |
Non-viral dried powders for respiratory gene delivery prepared by cationic and chitosan loaded liposomes.
Topics: Aerosols; Biological Availability; Cations; Cell Line; Chitosan; Deoxyribonuclease I; Desiccation; DNA; Drug Carriers; Electrophoresis, Agar Gel; Excipients; Genetic Therapy; Humans; Liposomes; Luciferases; Microscopy, Electron, Scanning; Particle Size; Powders; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
Inhibition of rat glioma cell migration and proliferation by a calix[8]arene scaffold exposing multiple GlcNAc and ureido functionalities.
Topics: Analysis of Variance; Animals; Benzimidazoles; Bromodeoxyuridine; Calixarenes; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclopentanes; Enzyme Activation; Focal Adhesion Kinase 1; Glioma; N-Acetylgalactosaminyltransferases; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Wounds and Injuries | 2008 |
Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery.
Topics: Cell Line; Cell Survival; DNA; Drug Delivery Systems; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Ethidium; Fatty Acids; Fluorescent Dyes; Gene Amplification; Green Fluorescent Proteins; Humans; Indicators and Reagents; Liposomes; Microscopy, Confocal; Nanoparticles; RNA, Small Interfering; Spermine; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Protective effects of epigallocatechin gallate after UV irradiation of cultured human lens epithelial cells.
Topics: Antioxidants; Catechin; Cell Count; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Lens, Crystalline; Radiation Injuries; Radiation-Protective Agents; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2008 |
Cytotoxic constituents from the bark of Salix hulteni.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Lung Neoplasms; Mass Spectrometry; Plant Bark; Salix; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2008 |
The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter.
Topics: Analysis of Variance; Animals; Carbon Isotopes; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cysteine; Humans; L-Lactate Dehydrogenase; Large Neutral Amino Acid-Transporter 1; Methylmercury Compounds; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2008 |
c-Jun N-terminal kinase mediates lactacystin-induced dopamine neuron degeneration.
Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Line; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Cytochromes c; Dopamine; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Substantia Nigra; Tetrazolium Salts; Thiazoles | 2008 |
Abeta mediated diminution of MTT reduction--an artefact of single cell culture?
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Electrophysiology; Hippocampus; Long-Term Potentiation; Male; Microglia; Neurons; Rats; Rats, Wistar; Synapses; Tetrazolium Salts; Thiazoles | 2008 |
Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA.
Topics: Antineoplastic Agents; Capillary Electrochromatography; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Delivery Systems; Enzyme Inhibitors; Excipients; Fatty Acids, Monounsaturated; Humans; Indicators and Reagents; Liposomes; Lung Neoplasms; Microscopy, Confocal; Oligonucleotides; Oligonucleotides, Antisense; Quaternary Ammonium Compounds; RNA, Antisense; Telomerase; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Expression, purification, and functional characterization of recombinant human interleukin-7.
Topics: Bioreactors; Blotting, Western; Chromatography, Ion Exchange; Cloning, Molecular; Fermentation; Humans; Interleukin-7; Pichia; Protein Renaturation; Recombinant Proteins; Sepharose; Tetrazolium Salts; Thiazoles; Transformation, Genetic | 2009 |
Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression.
Topics: Adjuvants, Immunologic; Animals; Body Weight; C-Reactive Protein; Cell Proliferation; Cell Survival; Cyclophosphamide; Drug Synergism; Immunosuppressive Agents; Killer Cells, Natural; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Organ Size; Panax; Polysaccharides; Pyrrolidonecarboxylic Acid; Spleen; Tetrazolium Salts; Thiazoles; Thiazolidines | 2008 |
Continentalic acid from Aralia continentalis induces growth inhibition and apoptosis in HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aralia; Blotting, Western; Caspase 3; Cell Line, Tumor; Diterpenes; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; L-Lactate Dehydrogenase; Protein Synthesis Inhibitors; Tetrazolium Salts; Thiazoles | 2008 |
A comparative study of inhibitory effect of human calprotectin on the growth of human gingival fibroblast and foreskin fibroblast.
Topics: Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Fibroblasts; Foreskin; Gingiva; Humans; Leukocyte L1 Antigen Complex; Male; Models, Biological; Neutrophils; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Ginsenoside Rg1 promotes bone marrow stromal cells proliferation via the activation of the estrogen receptor-mediated signaling pathway.
Topics: Animals; Bone Marrow Cells; Cell Proliferation; Estrogen Receptor alpha; Ginsenosides; Male; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Stromal Cells; Tetrazolium Salts; Thiazoles; Thymidine | 2008 |
Evaluation of the toxicity of oligonucleotide/cationic nanoemulsion complexes on Hep G2 cells through MTT assay.
Topics: Cations; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Coloring Agents; Drug Screening Assays, Antitumor; Emulsions; Humans; Nanoparticles; Oligonucleotides; Tetrazolium Salts; Thiazoles; Viscosity | 2008 |
Effect of tacrolimus on activity and expression of P-glycoprotein and ATP-binding cassette transporter A5 (ABCA5) proteins in hematoencephalic barrier cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Blotting, Western; Caspase 3; Cells, Cultured; Endothelial Cells; Fluoresceins; Humans; Immunosuppressive Agents; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus; Tetrazolium Salts; Thiazoles | 2008 |
Possible involvement of long chain fatty acids in the spores of Ganoderma lucidum (Reishi Houshi) to its anti-tumor activity.
Topics: Animals; Annexin A5; Antibiotics, Antineoplastic; Fatty Acids; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HL-60 Cells; Humans; In Vitro Techniques; Macrophages; Mice; Reishi; Spores, Fungal; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factors | 2008 |
The putrescine analogue 1,4-diamino-2-butanone affects polyamine synthesis, transport, ultrastructure and intracellular survival in Leishmania amazonensis.
Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cells, Cultured; Leishmania; Lipid Peroxidation; Macrophages; Mice; Microscopy, Electron, Transmission; Mitochondria; Ornithine Decarboxylase; Polyamines; Putrescine; Tetrazolium Salts; Thiazoles | 2008 |
Leonurus sibiricus induces nitric oxide and tumor necrosis factor-alpha in mouse peritoneal macrophages.
Topics: Actins; Animals; Blotting, Western; Cell Nucleus; Cells, Cultured; Electrophoretic Mobility Shift Assay; Endotoxins; In Vitro Techniques; Interferon-gamma; Leonurus; Macrophages, Peritoneal; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Pyrrolidines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tetrazolium Salts; Thiazoles; Thiocarbamates; Tumor Necrosis Factor-alpha | 2008 |
Implication of the Akt2/survivin pathway as a critical target in paclitaxel treatment in human ovarian cancer cells.
Topics: Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cell Separation; Female; Flow Cytometry; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Molecular Sequence Data; Neoplasm Proteins; Ovarian Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-akt; RNA Interference; Survivin; Tetrazolium Salts; Thiazoles | 2009 |
Lumican affects actin cytoskeletal organization in human melanoma A375 cells.
Topics: Actins; Apoptosis; Blotting, Western; Cell Survival; Chondroitin Sulfate Proteoglycans; Collagen; Cytoskeleton; Cytosol; Fibronectins; Humans; Isomerism; Keratan Sulfate; Lumican; Melanoma; Microscopy, Confocal; Microscopy, Fluorescence; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Tetrazolium Salts; Thiazoles | 2008 |
The role of surface receptor stimulation on the cytotoxicity of resveratrol to macrophages.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Culture Media; DNA Fragmentation; Lipopolysaccharides; Macrophages; Mice; Microscopy, Electron, Scanning; Nitrites; Receptors, Cell Surface; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4 | 2008 |
Progesterone inhibits human endothelial cell proliferation through a p53-dependent pathway.
Topics: Analysis of Variance; Cell Proliferation; Chromatin Immunoprecipitation; Collagen; DNA Primers; Drug Combinations; Endothelial Cells; Gene Expression Regulation; Humans; Laminin; Neovascularization, Physiologic; Progesterone; Proteoglycans; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53; Umbilical Veins | 2008 |
Histone acetylation resulting in resistance to methotrexate in choroid plexus cells.
Topics: Acetylation; Animals; Antigens, Viral, Tumor; Apoptosis; Benzamides; Carcinoma; Cell Line, Transformed; Cell Line, Tumor; Choroid Plexus; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Gamma Rays; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Inhibitory Concentration 50; Methotrexate; Mice; Pyridines; Tetrazolium Salts; Thiazoles; Valproic Acid | 2009 |
The effects of six root-end filling materials and their leachable components on cell viability.
Topics: 3T3 Cells; Animals; Cell Survival; Chromatography, High Pressure Liquid; Fibroblasts; Materials Testing; Mice; Mice, Inbred BALB C; Retrograde Obturation; Root Canal Filling Materials; Spectrophotometry, Atomic; Tetrazolium Salts; Thiazoles | 2008 |
Neural precursor cells as a novel target for interferon-beta.
Topics: Animals; Caspase 3; Cell Count; Cell Differentiation; Cell Proliferation; Cells, Cultured; Embryo, Mammalian; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Immunologic Factors; Interferon-beta; Mice; Nerve Tissue Proteins; Neuroglia; Neurons; Receptors, Interferon; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Prophylactic neuroprotective property of Centella asiatica against 3-nitropropionic acid induced oxidative stress and mitochondrial dysfunctions in brain regions of prepubertal mice.
Topics: Analysis of Variance; Animals; Body Weight; Brain; Centella; Dose-Response Relationship, Drug; Eating; Edema; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mitochondria; Nitro Compounds; Oxidative Stress; Plant Extracts; Protein Carbonylation; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Triterpenes | 2008 |
Lanthanum chloride suppresses hydrogen peroxide-enhanced calcification in rat calcifying vascular cells.
Topics: Animals; Aorta; Apoptosis; Calcium; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Lanthanum; MAP Kinase Signaling System; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Rats; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Synthesis and characterization of PEGylated calcium phosphate nanoparticles for oral insulin delivery.
Topics: Administration, Oral; Animals; Calcium Phosphates; Diabetes Mellitus, Experimental; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Insulin; Intestines; Kinetics; Nanoparticles; Nanotechnology; Polyethylene Glycols; Rats; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxic and genotoxic effects of [Ru(phi)3]2+ evaluated by Ames/Salmonella and MTT methods.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Repair; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Frameshift Mutation; Glioma; Molecular Structure; Mutagenicity Tests; Organometallic Compounds; Rats; Salmonella typhimurium; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxicity evaluation of four endodontic sealers.
Topics: Animals; Cells, Cultured; Coloring Agents; Composite Resins; Epoxy Resins; Free Radical Scavengers; Hydrogen Peroxide; Macrophages, Peritoneal; Materials Testing; Mice; Nitric Oxide; Oxidants; Reactive Oxygen Species; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Zinc Oxide-Eugenol Cement | 2008 |
Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Cell Count; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Enzyme Inhibitors; Glutamic Acid; Microglia; Neurons; Rats; Rats, Wistar; Staurosporine; Tetrazolium Salts; Thiazoles | 2008 |
(5R)-5-hydroxytriptolide inhibits the immune response of human peripheral blood mononuclear cells.
Topics: Antigen-Presenting Cells; Blotting, Western; Cell Proliferation; Cytokines; Diterpenes; Flow Cytometry; Genes, MHC Class I; Genes, MHC Class II; Humans; Immunity, Cellular; Immunosuppressive Agents; In Vitro Techniques; Interferon-gamma; Killer Cells, Natural; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mitogen-Activated Protein Kinases; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2009 |
Bioactivity, pharmacokinetics, and immunogenicity assays in preclinical and clinical trials for recombinant human endostatin.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Endostatins; Endothelial Cells; Female; Humans; Macaca mulatta; Male; Mice; Recombinant Proteins; Sex Characteristics; Tetrazolium Salts; Thiazoles | 2008 |
Oroxylin A induces G2/M phase cell-cycle arrest via inhibiting Cdk7-mediated expression of Cdc2/p34 in human gastric carcinoma BGC-823 cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; CDC2 Protein Kinase; Cell Division; Cell Line, Tumor; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Flavonoids; Flow Cytometry; G2 Phase; Gene Expression Regulation; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2008 |
Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol.
Topics: Acetic Acid; Analgesics; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Capillary Permeability; Carrageenan; Cell Survival; Chorioallantoic Membrane; Macrophages; Male; Mice; Mice, Inbred ICR; Nitrites; Tetrazolium Salts; Thiazoles | 2008 |
Cytotoxic activities of diarylheptanoids from Alnus japonica.
Topics: Alnus; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Diarylheptanoids; Drug Screening Assays, Antitumor; Humans; Mice; Plant Bark; Tetrazolium Salts; Thiazoles | 2008 |
A new ferulic acid ester and other constituents from Dracocephalum peregrinum.
Topics: Animals; Chromatography, Thin Layer; Coumaric Acids; Dimethyl Sulfoxide; Lamiaceae; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Plant Extracts; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Imaging of viral thymidine kinase gene expression by replicating oncolytic adenovirus and prediction of therapeutic efficacy.
Topics: Adenoviridae; Cell Line, Transformed; Cell Line, Tumor; Ganciclovir; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Oncolytic Virotherapy; Oncolytic Viruses; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transgenes; Viral Proteins; Virus Replication | 2008 |
Potential anti-respiratory syncytial virus lead compounds from Aglaia species.
Topics: Aglaia; Antineoplastic Agents, Phytogenic; Antiviral Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Immunohistochemistry; Inflammation; Kinetics; Respiratory Syncytial Virus, Human; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 2008 |
Histone deacetylase inhibitors from the rhizomes of Zingiber zerumbet.
Topics: Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Magnetic Resonance Spectroscopy; Plant Roots; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Zingiber officinale | 2008 |
Effects of heparin-binding epidermal growth factor-like growth factor on cell repopulation and signal transduction in periodontal ligament cells after scratch wounding in vitro.
Topics: Cell Proliferation; Cells, Cultured; Coloring Agents; Enzyme Activation; ErbB Receptors; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Signal Transduction; Tetrazolium Salts; Thiazoles; Wound Healing | 2009 |
Dynasore, a dynamin inhibitor, induces PAI-1 expression in MeT-5A human pleural mesothelial cells.
Topics: Cell Line; Dynamins; Endocytosis; Epithelium; Gene Expression Regulation; Humans; Hydrazones; MAP Kinase Kinase 4; Matrix Metalloproteinase 2; Models, Biological; Oxidative Stress; Plasminogen Activator Inhibitor 1; Pleura; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2009 |
Flavonoid constituents from Spiranthes australis LINDL.
Topics: Cell Line, Tumor; Chromatography, Thin Layer; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Flavonoids; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Orchidaceae; Solvents; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2008 |
Medicinal flowers. XXIII. New taraxastane-type triterpene, punicanolic acid, with tumor necrosis factor-alpha inhibitory activity from the flowers of Punica granatum.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Cell Line, Tumor; Drug Screening Assays, Antitumor; Flowers; Humans; Lythraceae; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Triterpenes; Tumor Necrosis Factor-alpha | 2008 |
Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line.
Topics: Cell Line; Cell Survival; Drug Evaluation, Preclinical; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Keratinocytes; Light; Microscopy, Electron, Transmission; Nanoparticles; Oxazines; Quantum Dots; Scattering, Radiation; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Trypan Blue; Xanthenes | 2009 |
In vitro evaluation of cytotoxicity of soft lining materials on L929 cells by MTT assay.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Survival; Denture Liners; Mice; Tetrazolium Salts; Thiazoles | 2009 |
Novel anthraquinone derivatives: synthesis via click chemistry approach and their induction of apoptosis in BGC gastric cancer cells via reactive oxygen species (ROS)-dependent mitochondrial pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chemistry, Pharmaceutical; Cytoplasm; Drug Design; Flow Cytometry; Humans; Inhibitory Concentration 50; Membrane Potentials; Microscopy, Confocal; Mitochondria; Permeability; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2008 |
Synthesis of chiral 3-methyl- and 3-methyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline and prevention of MPP+ -induced cytotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Death; Data Interpretation, Statistical; Dopamine Agents; Dopamine Antagonists; Models, Molecular; PC12 Cells; Rats; Stereoisomerism; Structure-Activity Relationship; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles | 2008 |
Chlorpyrifos induces apoptosis in human T cells.
Topics: Annexin A5; Apoptosis; Caspase 3; Cell Death; Chlorpyrifos; DNA; DNA Fragmentation; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Indicators and Reagents; Insecticides; Jurkat Cells; L-Lactate Dehydrogenase; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2009 |
Paclitaxel induces up-regulation of tissue factor in human aortic endothelial cells.
Topics: Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Blotting, Western; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; In Vitro Techniques; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thrombin; Thromboplastin; Up-Regulation | 2009 |
First synthesis of N-[(aziridin-2-yl)methyl]benzimidazolequinone and analysis of toxicity towards normal and Fanconi anemia cells.
Topics: Aziridines; Benzimidazoles; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Fibroblasts; Humans; Molecular Structure; Quinolines; Skin; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2008 |
The CellScan technology for in vitro studies on novel platinum complexes with organoarsenic ligands.
Topics: Antineoplastic Agents; Arsenicals; Cell Line, Tumor; Comet Assay; Crystallography, X-Ray; Culture Media; Drug Screening Assays, Antitumor; Humans; Lasers; Ligands; Magnetic Resonance Spectroscopy; Microscopy, Fluorescence; Molecular Conformation; Mutagens; Organoplatinum Compounds; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2008 |
Effects of sodium fluoride treatment in vitro on cell proliferation, apoptosis and caspase-3 and caspase-9 mRNA expression by neonatal rat osteoblasts.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; Caspase 3; Caspase 9; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Osteoblasts; Rats; Rats, Wistar; RNA, Messenger; Skull; Sodium Fluoride; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Methylated N-(4-N,N-dimethylaminobenzyl) chitosan, a novel chitosan derivative, enhances paracellular permeability across intestinal epithelial cells (Caco-2).
Topics: Caco-2 Cells; Chitosan; Dextrans; Fluorescein-5-isothiocyanate; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Magnetic Resonance Spectroscopy; Methylation; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tight Junctions | 2008 |
Melatonin induces cell cycle arrest and apoptosis in hepatocarcinoma HepG2 cell line.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Flow Cytometry; Humans; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Melatonin; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2008 |
Glutamate and nitric oxide modulate ERK and CREB phosphorylation in the avian retina: evidence for direct signaling from neurons to Müller glial cells.
Topics: Animals; Cell Communication; Cell Survival; Cells, Cultured; Chick Embryo; CREB-Binding Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agents; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; In Vitro Techniques; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Phosphorylation; Retina; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Autoradiography; Benzoquinones; Caspase 3; Cell Line, Tumor; Copper; Cytochromes c; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; NAD; Neuroblastoma; Phenanthrolines; Phosphorus Isotopes; Salsoline Alkaloids; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Cytokine Receptor gp130; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Hydrogen Peroxide; Interleukin-6; Neuroglia; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2009 |
Reactive oxygen species production and MAPK activation are implicated in tetrahydrobiopterin-induced SH-SY5Y cell death.
Topics: Biopterins; Cell Death; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
2-Deoxy-d-glucose protects neural progenitor cells against oxidative stress through the activation of AMP-activated protein kinase.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cell Proliferation; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypoglycemic Agents; L-Lactate Dehydrogenase; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Ribonucleotides; Stem Cells; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells.
Topics: alpha-Synuclein; Analysis of Variance; Apoptosis; Cell Line, Tumor; Dopamine; Drug Combinations; Gene Expression Regulation, Neoplastic; Humans; Hydroxycholesterols; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neuroblastoma; Norepinephrine; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2008 |
Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells.
Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Endothelium, Vascular; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasm Metastasis; Neovascularization, Pathologic; Pregnenediones; Promoter Regions, Genetic; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2008 |
Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Doxorubicin; Drug Resistance, Multiple; Humans; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors; Vincristine | 2008 |
Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; Fluorouracil; Humans; Hyaluronan Receptors; In Vitro Techniques; Spheroids, Cellular; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Orotate Phosphoribosyltransferase; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stomach Neoplasms; Taxoids; Tetrazolium Salts; Thiazoles | 2008 |
AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Curcumin; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetrazolium Salts; Thiazoles | 2008 |
A new abietane diterpenoid from Isodon inflexus.
Topics: Abietanes; Animals; Cell Survival; Diterpenes; Isodon; Macrophages; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Nitric Oxide; Plant Extracts; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2008 |
Microencapsulation of antibiotic rifampicin in poly(3-hydroxybutyrate-co-3-hydroxyvalerate).
Topics: Animals; Antibiotics, Antitubercular; Cell Line; Cricetinae; Drug Compounding; Excipients; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Nanoparticles; Neutral Red; Nucleic Acid Synthesis Inhibitors; Particle Size; Polyesters; Rifampin; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2008 |
Development of highly stable and low toxic cationic liposomes for gene therapy.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Cations; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Compounding; Drug Stability; Excipients; Freeze Drying; Genetic Therapy; HeLa Cells; Humans; Liposomes; Mice; Quaternary Ammonium Compounds; Tetrazolium Salts; Thiazoles | 2008 |
Effects of the association between a calcium hydroxide paste and 0.4% chlorhexidine on the development of the osteogenic phenotype in vitro.
Topics: Alkaline Phosphatase; Animals; Bone Matrix; Calcification, Physiologic; Calcium Hydroxide; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Chlorhexidine; Coloring Agents; Drug Combinations; Fluorescent Dyes; Indoles; Integrin-Binding Sialoprotein; Organic Chemicals; Osteoblasts; Osteogenesis; Osteopontin; Proteins; Rats; Rats, Wistar; Root Canal Filling Materials; Root Canal Irrigants; Sialoglycoproteins; Tetrazolium Salts; Thiazoles | 2008 |
Ultrafine PEG-PLA fibers loaded with both paclitaxel and doxorubicin hydrochloride and their in vitro cytotoxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chemistry, Pharmaceutical; Doxorubicin; Drug Delivery Systems; Flow Cytometry; Humans; In Vitro Techniques; Lactic Acid; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Rats; Technology, Pharmaceutical; Tetrazolium Salts; Thiazoles | 2009 |
Activation of the FGF2/FGFR1 autocrine loop for cell proliferation and survival in uveal melanoma cells.
Topics: Apoptosis; Autocrine Communication; Blotting, Western; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotides, Antisense; Proto-Oncogene Proteins B-raf; Receptor, Fibroblast Growth Factor, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thionucleotides; Tumor Cells, Cultured; Uveal Neoplasms | 2009 |
RGD peptide-immobilized electrospun matrix of polyurethane for enhanced endothelial cell affinity.
Topics: Biocompatible Materials; Cell Proliferation; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Microscopy, Electron, Scanning; Models, Chemical; Oligopeptides; Peptides; Polyethylene Glycols; Polyurethanes; Porosity; Surface Properties; Tetrazolium Salts; Thiazoles | 2008 |
Reduction of beta-amyloid-induced neurotoxicity on hippocampal cell cultures by moderate acidosis is mediated by transforming growth factor beta.
Topics: Acidosis; Amyloid beta-Peptides; Analysis of Variance; Animals; Azides; Benzamides; Cell Size; Dioxoles; Embryo, Mammalian; Female; Hippocampus; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Neurons; Nitric Oxide; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta; Tubulin | 2009 |
Beta-ecdysterone induces osteogenic differentiation in mouse mesenchymal stem cells and relieves osteoporosis.
Topics: Alkaline Phosphatase; Animals; Azo Compounds; Bone and Bones; Bone Density; Bone Density Conservation Agents; Cell Differentiation; Coloring Agents; Ecdysterone; Genes, Reporter; Indicators and Reagents; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Osteogenesis; Osteoporosis; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection; Tretinoin | 2008 |
Establishment of a cell-based assay to screen regulators of the hypoxia-inducible factor-1-dependent vascular endothelial growth factor promoter.
Topics: Cell Line; Cell Survival; Cobalt; DNA; Drug Evaluation, Preclinical; Drug Resistance; Endothelial Cells; Humans; Hypoxia-Inducible Factor 1; Luciferases; Neomycin; Neovascularization, Physiologic; Plasmids; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Transfection; Vascular Endothelial Growth Factor A | 2008 |
Genotoxic and cytotoxic effects produced by acetogenins obtained from Annona cherimolia Mill.
Topics: Acetogenins; Animals; Annona; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Cell Survival; Drug Screening Assays, Antitumor; Erythrocytes; Humans; In Vitro Techniques; Isomerism; Lethal Dose 50; Mice; Micronucleus Tests; Mutagens; Seeds; Tetrazolium Salts; Thiazoles | 2008 |
Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier.
Topics: alpha-Tocopherol; Animals; Astrocytes; Astrocytoma; Biological Transport, Active; Blood-Brain Barrier; Blotting, Western; Capillaries; Carrier Proteins; Cerebrovascular Circulation; CHO Cells; Coculture Techniques; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Fluorescent Antibody Technique; Glycoproteins; Humans; Lipoproteins, HDL; Mice; Mice, Inbred C57BL; Recombinant Proteins; RNA; Serum Albumin; Serum Albumin, Human; Swine; Tetrazolium Salts; Thiazoles | 2009 |
Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Benzimidazoles; Cell Death; Chromatography, High Pressure Liquid; Cysteine; Dopamine; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Monophenol Monooxygenase; Mutation; Nerve Growth Factor; Oxidation-Reduction; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Effects of macrolides on proinflammatory epitopes on endothelial cells in vitro.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Antigens, CD34; Cell Death; Cell Line; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Endothelium, Vascular; Fibroblasts; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Inhibitory Concentration 50; Intercellular Adhesion Molecule-1; Macrolides; Mice; Phycoerythrin; Tetrazolium Salts; Thiazoles; Time Factors; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Virginiamycin | 2009 |
Mechanism of okadaic acid-induced neuronal death and the effect of estrogens.
Topics: Animals; Caspase 3; Caspase 7; Cell Death; Cells, Cultured; Cerebral Cortex; Cytosol; Enzyme Inhibitors; Estrogens; Female; Glutamic Acid; Lipid Peroxidation; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Okadaic Acid; Pregnancy; Protein Carbonylation; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
Oxygen consumption and blood flow distribution in perfused skeletal muscle of chinook salmon.
Topics: Analysis of Variance; Animals; Blood Pressure; Electric Stimulation; Microspheres; Mitochondria; Muscle, Skeletal; New Zealand; Oxygen; Oxygen Consumption; Regional Blood Flow; Salmon; Tail; Tetrazolium Salts; Thiazoles | 2009 |
Synthesis, characterization and biological activities of thymopentin ethyl ester.
Topics: Animals; Antioxidants; Cell Proliferation; Colorimetry; Esters; Half-Life; Hydrocortisone; Immunosuppressive Agents; Lipids; Lymphocytes; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thymopentin | 2008 |
Antiproliferative activity of the total saponin of Solanum lyratum Thunb in Hela cells by inducing apoptosis.
Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cell Death; Cell Proliferation; Cytochromes c; DNA Fragmentation; Flow Cytometry; HeLa Cells; Humans; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Saponins; Signal Transduction; Solanum; Tetrazolium Salts; Thiazoles | 2008 |
Evaluation the anti proliferative activity of structural proteins and fraction of supernatant from culture of Candida albicans.
Topics: Animals; Candida albicans; Cell Extracts; Cell Proliferation; Culture Media; Lymphocytes; Mice; Mice, Inbred BALB C; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2007 |
1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.
Topics: Animals; Benzhydryl Compounds; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Humans; Indoles; Ligands; Male; Mice; Mice, Nude; Models, Biological; Neoplasm Transplantation; Nuclear Receptor Subfamily 4, Group A, Member 2; RNA Interference; Tetrazolium Salts; Thiazoles; Transcription Factors; Urinary Bladder Neoplasms | 2008 |
15-HETE suppresses K(+) channel activity and inhibits apoptosis in pulmonary artery smooth muscle cells.
Topics: Apoptosis; Arachidonic Acid; Caspase 3; Humans; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Hypoxia; Mitochondria; Models, Biological; Myocytes, Smooth Muscle; Potassium; Potassium Channels; Proto-Oncogene Proteins c-bcl-2; Pulmonary Artery; Tetrazolium Salts; Thiazoles | 2009 |
Screen anticancer drug in vitro using resonance light scattering technique.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Colorimetry; Drug Screening Assays, Antitumor; Formazans; Humans; Inhibitory Concentration 50; Light; Mice; Neoplasms; Scattering, Radiation; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
The behavior of mesenchymal stem cells on micropatterned PLLA membranes.
Topics: Adult; Biocompatible Materials; Bone Marrow Cells; Cell Adhesion; Cell Survival; Dimethylpolysiloxanes; Elastomers; Flow Cytometry; Humans; Lactic Acid; Mesenchymal Stem Cells; Middle Aged; Polyesters; Polymers; Silicones; Surface Properties; Tetrazolium Salts; Thiazoles | 2009 |
Transport of mistletoe lectin by M cells in human intestinal follicle-associated epithelium (FAE) in vitro.
Topics: B-Lymphocytes; Blotting, Western; Caco-2 Cells; Cell Line; Coculture Techniques; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Galectins; Humans; Intestinal Mucosa; Lectins; Mistletoe; Tetrazolium Salts; Thiazoles | 2008 |
Isoliquiritigenin induces monocytic differentiation of HL-60 cells.
Topics: Antioxidants; CD11b Antigen; Cell Differentiation; Cell Proliferation; Cell Separation; Cell Survival; Chalcones; Flow Cytometry; Glycyrrhiza; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Monocytes; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
Antitumor efficiency of the cytosine deaminase/5-fluorocytosine suicide gene therapy system on malignant gliomas: an in vivo study.
Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine Deaminase; DNA Primers; Escherichia coli; Flucytosine; Fluorescent Antibody Technique; Fluorouracil; Genetic Therapy; Glioma; Immunoblotting; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2009 |
In vitro susceptibility of dermatophytes to conventional and alternative antifungal agents.
Topics: Antifungal Agents; Arthrodermataceae; Biomass; Cyclohexane Monoterpenes; Fluconazole; Humans; Lipopeptides; Microbial Sensitivity Tests; Microbial Viability; Microsporum; Monoterpenes; Mycoses; Tetrazolium Salts; Thiazoles; Trichophyton | 2009 |
Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica Thunb.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Crystallography, X-Ray; Dimerization; Humans; Inula; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Molecular Structure; Neoplasms; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sesquiterpenes, Guaiane; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2009 |
3-Oxoolean-12-en-27-oic acid isolated from Aceriphyllum rossii induces caspase-8-dependent apoptosis in human promyelocytic leukemia HL-60 cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 8; Cell Line, Transformed; Dose-Response Relationship, Drug; Fas Ligand Protein; Fas-Associated Death Domain Protein; HL-60 Cells; Humans; Neuroprotective Agents; RNA, Messenger; Saxifragaceae; Serine Endopeptidases; Tetrazolium Salts; Thiazoles; Time Factors; Triterpenes | 2009 |
Selective killing of leukemia and lymphoma cells ectopically expressing hCGbeta by a conjugate of curcumin with an antibody against hCGbeta subunit.
Topics: Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Separation; Chorionic Gonadotropin, beta Subunit, Human; Curcumin; Drug Design; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Lymphoma; Male; Middle Aged; Sialic Acid Binding Ig-like Lectin 3; Tetrazolium Salts; Thiazoles; U937 Cells | 2009 |
Advanced glycation end products increase transglutaminase activity in primary porcine tenocytes.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Lysine; RNA, Messenger; Stifle; Swine; Tendons; Tetrazolium Salts; Thiazoles; Transglutaminases | 2009 |
Lipocalin-2 is an autocrine mediator of reactive astrocytosis.
Topics: Amides; Analysis of Variance; Animals; Animals, Newborn; Annexin A2; Apoptosis; Astrocytes; Autocrine Communication; Brain; Cell Movement; Cells, Cultured; Embryo, Nonmammalian; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Inbred ICR; Nitrites; Nitroprusside; Penicillamine; Phagocytes; Propidium; Pyridines; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha; Zebrafish | 2009 |
Can MTT be used to quantify the antioxidant activity of plant extracts?
Topics: Antioxidants; Plant Extracts; Tetrazolium Salts; Thiazoles | 2009 |
Ceramidastin, a novel bacterial ceramidase inhibitor, produced by Penicillium sp. Mer-f17067.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Ceramidases; Cyclooctanes; Dermatitis, Atopic; Enzyme Inhibitors; Female; Fermentation; Humans; Magnetic Resonance Spectroscopy; Maleic Anhydrides; Mice; Mice, Inbred ICR; Molecular Conformation; Penicillium; Pseudomonas; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxicity of endodontic materials over 6-weeks ex vivo.
Topics: Animals; Cell Line; Cell Survival; Coloring Agents; Composite Resins; Dimethylpolysiloxanes; Drug Combinations; Epoxy Resins; Fibroblasts; Forecasting; Gutta-Percha; Materials Testing; Mice; Mitochondria; Polyesters; Resin Cements; Root Canal Filling Materials; Safety; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors; Zinc Oxide-Eugenol Cement | 2008 |
The biocompatibility of modified experimental Portland cements with potential for use in dentistry.
Topics: Aluminum; Aluminum Compounds; Biocompatible Materials; Calcium Compounds; Cell Line, Tumor; Cell Survival; Coloring Agents; Dental Cements; Fluorine; Glass Ionomer Cements; Humans; Humidity; Indicators and Reagents; Materials Testing; Oxazines; Sulfur Compounds; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2008 |
Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung ep
Topics: Apoptosis; Autophagy; Blotting, Western; Capsaicin; Cell Line; Cell Survival; Cytoplasm; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; Lung; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinases; Protein Folding; Tetrazolium Salts; Thiazoles; Transfection; Vacuoles | 2009 |
In vitro chemosensitivity of canine mast cell tumors grades II and III to all-trans-retinoic acid (ATRA).
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Male; Mast Cells; Mastocytosis; Tetrazolium Salts; Thiazoles; Tretinoin; Tumor Cells, Cultured | 2009 |
In vitro anti-biofilm activity of Boswellia spp. oleogum resin essential oils.
Topics: Bacterial Adhesion; Biofilms; Boswellia; Candida albicans; Growth Inhibitors; Microbial Sensitivity Tests; Microbial Viability; Oils, Volatile; Staining and Labeling; Staphylococcus aureus; Staphylococcus epidermidis; Tetrazolium Salts; Thiazoles | 2008 |
Histoculture drug response assay predicts the postoperative prognosis of patients with esophageal cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Coloring Agents; Combined Modality Therapy; Digestive System Surgical Procedures; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Humans; Kaplan-Meier Estimate; Postoperative Period; Prognosis; Radiotherapy; Retrospective Studies; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles | 2009 |
Different immunomodulatory effects associated with sub-micrometer particles in ambient air from rural, urban and industrial areas.
Topics: Air Pollutants; Air Pollutants, Occupational; Argentina; Cytokines; Dose-Response Relationship, Drug; Dust; Enzyme-Linked Immunosorbent Assay; Humans; Immunity, Cellular; Immunologic Factors; Interferon-gamma; Interleukin-4; Monocytes; Nanoparticles; Particle Size; Phytohemagglutinins; Polycyclic Aromatic Hydrocarbons; Rural Health; Spectrometry, Fluorescence; T-Lymphocytes, Helper-Inducer; Tetrazolium Salts; Thiazoles; Urban Health | 2009 |
Improvement of cytocompatibility of electrospinning PLLA microfibers by blending PVP.
Topics: Biocompatible Materials; Cell Proliferation; Cells, Cultured; Coloring Agents; Humans; Methylene Chloride; Microscopy, Confocal; Microscopy, Electron, Scanning; Molecular Weight; Muscle, Smooth, Vascular; Platelet Adhesiveness; Polyesters; Povidone; Solvents; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Hydrogel-magnetic nanoparticles with immobilized L-asparaginase for biomedical applications.
Topics: Animals; Biocompatible Materials; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Coloring Agents; Drug Delivery Systems; Enzyme Stability; Enzymes, Immobilized; Hydrogel, Polyethylene Glycol Dimethacrylate; Light; Magnetics; Nanoparticles; Nanotechnology; Particle Size; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Vero Cells | 2009 |
High cytotoxic sensitivity of the oligodendrocyte precursor cells to HSP90 inhibitors in cell cultures.
Topics: Animals; Benzoquinones; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Gangliosides; Glial Fibrillary Acidic Protein; HSP90 Heat-Shock Proteins; Inhibitory Concentration 50; Lactams, Macrocyclic; Macrolides; O Antigens; Oligodendroglia; Rats; Stem Cells; Tetrazolium Salts; Thiazoles; Tubulin | 2009 |
Effects of red light emitting diode on apoptosis of HeLa cells and suppression of implanted HeLa cells growth in mice.
Topics: Animals; Apoptosis; Calcium; Caspases; Cell Cycle; Flow Cytometry; HeLa Cells; Humans; Light; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Tetrazolium Salts; Thiazoles | 2009 |
Coumestrol promotes proliferation and osteoblastic differentiation in rat bone marrow stromal cells.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Coumestrol; Gene Expression Regulation; Osteoblasts; Osteogenesis; Osteoprotegerin; Phytoestrogens; RANK Ligand; Rats; Receptors, Estrogen; Stromal Cells; Tetrazolium Salts; Thiazoles | 2009 |
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Coloring Agents; Dendrimers; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Molecular Structure; Molecular Weight; Photochemotherapy; Photosensitizing Agents; Porphyrins; Protoporphyrins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Time Factors; Xenograft Model Antitumor Assays | 2009 |
Multiple endpoint analysis of the 3D-reconstituted corneal epithelium after treatment with benzalkonium chloride: early detection of toxic damage.
Topics: Benzalkonium Compounds; Cadherins; Caspase 3; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium, Corneal; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Ki-67 Antigen; Membrane Proteins; Microscopy, Confocal; Occludin; Preservatives, Pharmaceutical; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2009 |
Evaluation of the skin irritation using a DNA microarray on a reconstructed human epidermal model.
Topics: DNA; Epidermal Cells; Epidermis; Gene Expression; HSP70 Heat-Shock Proteins; Humans; Irritants; Myeloid Differentiation Factor 88; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; Receptors, Interleukin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA; Skin; Sodium Dodecyl Sulfate; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2009 |
Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells.
Topics: Animals; Blotting, Western; Cadmium; Caspase 9; Cell Line; Cell Survival; Drugs, Chinese Herbal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hair Cells, Auditory; Hearing Disorders; Humans; Indicators and Reagents; Mice; Organ Culture Techniques; Organ of Corti; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
Novel norhumulene and xeniaphyllane-derived terpenoids from a formosan soft coral Sinularia gibberosa.
Topics: Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Diterpenes; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Monocyclic Sesquiterpenes; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Taiwan; Terpenes; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxicity screening for the cyanobacterial toxin cylindrospermopsin.
Topics: Alkaloids; Animals; Bacterial Toxins; Cell Line; Cell Survival; Cyanobacteria; Cyanobacteria Toxins; Humans; Tetrazolium Salts; Thiazoles; Time Factors; Uracil | 2009 |
Initial osteoblast functions on Ti-5Zr-3Sn-5Mo-15Nb titanium alloy surfaces modified by microarc oxidation.
Topics: Alloys; Animals; Animals, Newborn; Biocompatible Materials; Cell Adhesion; Cell Survival; Cells, Cultured; Coloring Agents; Gene Expression Profiling; Microscopy, Electron, Scanning; Osteoblasts; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Surface Properties; Surface Tension; Tetrazolium Salts; Thiazoles | 2010 |
Newcastle disease virus represses the activation of human hepatic stellate cells and reverses the development of hepatic fibrosis in mice.
Topics: Actins; Animals; Apoptosis; Biomarkers; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Collagen Type I; Culture Media, Conditioned; Cytopathogenic Effect, Viral; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms; Mice; Newcastle disease virus; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Virus Replication | 2009 |
Determining the cytotoxicity of catanionic surfactant mixtures on HeLa cells.
Topics: Anions; Cations; Drug Delivery Systems; HeLa Cells; Humans; Inhibitory Concentration 50; Mitochondria; Polyethylene; Surface Properties; Surface Tension; Surface-Active Agents; Tetrazolium Salts; Thiazoles | 2009 |
Effects of Gingko Extract (EGb761) on oxidative damage under different conditions of serum supply.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Line, Tumor; Culture Media; Electron Transport Complex IV; Flow Cytometry; Ginkgo biloba; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Plant Extracts; Rats; Serum; Tetrazolium Salts; Thiazoles | 2009 |
The effect of extracellular calcium and inorganic phosphate on the growth and osteogenic differentiation of mesenchymal stem cells in vitro: implication for bone tissue engineering.
Topics: Alkaline Phosphatase; Bone and Bones; Calcium; Calcium Phosphates; Cell Differentiation; Cell Proliferation; Collagen; Humans; Mesenchymal Stem Cells; Osteocalcin; Osteogenesis; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2009 |
Porous bioactive scaffold of aliphatic polyurethane and hydroxyapatite for tissue regeneration.
Topics: Calorimetry, Differential Scanning; Cell Line, Tumor; Coculture Techniques; Durapatite; Humans; Microscopy, Electron, Scanning; Osteosarcoma; Polyurethanes; Porosity; Powders; Regeneration; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2009 |
Mechanical tensile stress effects on the expression of bone sialoprotein in bovine cementoblasts.
Topics: Animals; Animals, Newborn; Antibodies; Calcification, Physiologic; Cattle; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Coloring Agents; Dental Cementum; Dental Stress Analysis; Integrin-Binding Sialoprotein; Osteoblasts; Periodontal Ligament; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Root; Up-Regulation | 2009 |
In vitro antibacterial and cytotoxicity assessments of an orthodontic bonding agent containing benzalkonium chloride.
Topics: Anti-Bacterial Agents; Benzalkonium Compounds; Boron Compounds; Cells, Cultured; Colony Count, Microbial; Coloring Agents; Cytotoxins; Dental Bonding; Fibroblasts; Gingiva; Humans; Materials Testing; Methacrylates; Methylmethacrylates; Orthodontic Brackets; Resin Cements; Streptococcus mutans; Streptococcus sobrinus; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2009 |
Removal of red light minimizes methylene blue-stimulated DNA damage in oesophageal cells: implications for chromoendoscopy.
Topics: Analysis of Variance; Apoptosis; Barrett Esophagus; Cell Line, Tumor; Comet Assay; DNA Damage; Endoscopy, Digestive System; Humans; Light; Methylene Blue; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
(-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation.
Topics: Adrenergic Agents; Analysis of Variance; Catechin; Cell Death; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Neuroblastoma; Neuroprotective Agents; Oxidopamine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium; Tyrosine | 2009 |
nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing.
Topics: ADAM Proteins; ADAM10 Protein; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Antigens, Surface; Brain; Case-Control Studies; Cell Cycle; Cell Line, Tumor; Disease Progression; ELAV Proteins; ELAV-Like Protein 1; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Humans; Male; Membrane Proteins; Neuroblastoma; Peptide Fragments; Postmortem Changes; RNA-Binding Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2009 |
Induction of hepatocyte growth factor production in human dermal fibroblasts and their proliferation by the extract of bitter melon pulp.
Topics: Cell Proliferation; Cucurbitaceae; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Hepatocyte Growth Factor; Humans; Models, Biological; Phosphorylation; Plant Extracts; Skin; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Cytotoxicity of local anesthetics in human neuronal cells.
Topics: Anesthetics, Local; Apoptosis; Calcium; Carbachol; Caspases; Cell Line, Tumor; Cell Survival; Colorimetry; Enzyme Activation; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Muscarinic Agonists; Neurons; Potassium Channel Blockers; Tetraethylammonium; Tetrazolium Salts; Tetrodotoxin; Thiazoles | 2009 |
Porphyrins containing nitric oxide donors: Synthesis and cancer cell-oriented NO release.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Porphyrins; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Photo and pH stable, highly-luminescent silicon nanospheres and their bioconjugates for immunofluorescent cell imaging.
Topics: Biocompatible Materials; Cell Survival; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Light; Luminescence; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanospheres; Nanotechnology; Silicon; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Water | 2009 |
Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 production and activation.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Collagen; Cyclooxygenase 2 Inhibitors; Down-Regulation; Drug Combinations; Enzyme Activation; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Laminin; Matrix Metalloproteinase 2; Mouth Neoplasms; Neoplasm Invasiveness; Proteoglycans; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-2 | 2009 |
A new G6PD knockdown tumor-cell line with reduced proliferation and increased susceptibility to oxidative stress.
Topics: Antioxidants; Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Glucosephosphate Dehydrogenase; Humans; Lentivirus; Melanoma; Molecular Sequence Data; Oxidative Stress; Plasmids; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
The antitumor effects of CIK cells combined with docetaxel against drug-resistant lung adenocarcinoma cell line SPC-A1/DTX in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Immunotherapy; Killer Cells, Natural; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Taxoids; Tetrazolium Salts; Thiazoles | 2009 |
In-vitro bioactivity of Venda medicinal plants used in the treatment of respiratory conditions.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Bacteria; Chromans; Fungi; Medicine, African Traditional; Microbial Sensitivity Tests; Plant Extracts; Plants, Medicinal; Respiratory Tract Diseases; Tetrazolium Salts; Thiazoles | 2008 |
Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor.
Topics: Adenosine Triphosphate; Animals; Calcium; Caspases; Cell Death; Cell Differentiation; Cells, Cultured; Chelating Agents; Corpus Striatum; Egtazic Acid; Embryo, Mammalian; Embryonic Stem Cells; Enzyme Inhibitors; Extracellular Fluid; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neurons; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Fluorescent Dyes; Humans; Indicators and Reagents; Multidrug Resistance-Associated Proteins; Oncogene Protein v-akt; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA Interference; Tetrazolium Salts; Thiazoles | 2009 |
Study on the enhanced cellular uptake effect of daunorubicin on leukemia cells mediated via functionalized nickel nanoparticles.
Topics: Antineoplastic Agents; Biocompatible Materials; Cell Line, Tumor; Daunorubicin; Electrochemistry; Humans; K562 Cells; Leukemia; Metal Nanoparticles; Microscopy, Atomic Force; Microscopy, Fluorescence; Nanotechnology; Nickel; Permeability; Tetrazolium Salts; Thiazoles | 2009 |
Aqueous synthesis of gold nanoparticles and their cytotoxicity in human dermal fibroblasts-fetal.
Topics: Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Death; Cell Survival; Citrates; Fetus; Fibroblasts; Gold; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanotechnology; Sodium Citrate; Tetrazolium Salts; Thiazoles; Water | 2009 |
The effect of a cholesterol liquid crystalline structure on osteoblast cell behavior.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cell Proliferation; Cholesterol; Chromatography; Magnetic Resonance Spectroscopy; Mice; Microscopy, Polarization; Models, Chemical; Osteoblasts; Polymers; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2009 |
Des-gamma-carboxy prothrombin stimulates human vascular endothelial cell growth and migration.
Topics: Biomarkers; Cell Line; Cell Movement; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Endothelial Cells; ErbB Receptors; Gene Expression Regulation, Enzymologic; Humans; Laminin; Matrix Metalloproteinase 2; Neovascularization, Pathologic; Protein Precursors; Proteoglycans; Prothrombin; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor A | 2009 |
Bmf is upregulated by PS-341-mediated cell death of glioma cells through JNK phosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Antineoplastic Agents; Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; DNA Fragmentation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioma; Humans; MAP Kinase Kinase 4; Phosphorylation; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Rheological blends for drug delivery. II. Prolongation of nerve blockade, biocompatibility, and in vitro-in vivo correlations.
Topics: Anesthetics, Local; Animals; Biocompatible Materials; Bupivacaine; Cell Line; Coloring Agents; Drug Delivery Systems; Hyaluronic Acid; Hypromellose Derivatives; Inflammation; Male; Methylcellulose; Molecular Weight; Nerve Block; Rats; Rats, Sprague-Dawley; Rheology; Sciatic Nerve; Solutions; Tetrazolium Salts; Thiazoles; Viscosity | 2010 |
Pennicitrinone D, a new citrinin dimer from the halotolerant fungus Penicillium notatum B-52.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Citrinin; Culture Media; Dimerization; Fermentation; Humans; Magnetic Resonance Spectroscopy; Penicillium chrysogenum; Salts; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.
Topics: Acid Anhydride Hydrolases; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Hydrolysis; Mutation; Neoplasm Proteins; Phosphorylation; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Tetrazolium Salts; Thiazoles; Tumor Suppressor Proteins | 2009 |
Non-genomic inhibitory signaling of beta-carotene in squamous cell carcinoma of the lungs.
Topics: beta Carotene; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Neoplastic; Humans; Immunoassay; Lung Neoplasms; Models, Biological; Phosphorylation; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
The skin compatibility of distilled tall oils: evaluation with the bovine udder skin in vitro model system.
Topics: Animal Testing Alternatives; Animals; Cattle; Cell Survival; Dinoprostone; Female; Irritants; Mammary Glands, Animal; Models, Animal; Oils; Skin; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2009 |
Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer.
Topics: Adenoviridae; Animals; Apoptosis; Benzimidazoles; Cell Death; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Coloring Agents; Cytopathogenic Effect, Viral; Eosine Yellowish-(YS); Female; Fluorescent Dyes; Gene Expression; Genetic Therapy; Genetic Vectors; Gentian Violet; HCT116 Cells; Hematoxylin; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Oncolytic Virotherapy; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Transport evaluation of alendronate across Caco-2 cell monolayers.
Topics: Absorption; Alendronate; beta-Cyclodextrins; Biological Transport, Active; Bone Density Conservation Agents; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; Electric Impedance; Excipients; Humans; Taurocholic Acid; Tetrazolium Salts; Thiazoles | 2009 |
Octreotide inhibits growth of colonic cancer SW480 cells by modulating the Wnt/P-catenin pathway.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; beta Catenin; Blotting, Western; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indicators and Reagents; Octreotide; Oligonucleotide Array Sequence Analysis; Signal Transduction; Tetrazolium Salts; Thiazoles; Wnt Proteins | 2009 |
Involvement of protein trafficking in deprenyl-induced alpha-secretase activity regulation in PC12 cells.
Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Brefeldin A; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Neuroprotective Agents; PC12 Cells; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Selegiline; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Conjugation with alpha-linolenic acid improves cancer cell uptake and cytotoxicity of doxorubicin.
Topics: alpha-Linolenic Acid; Cell Line, Tumor; Chemistry, Pharmaceutical; Chromatography, Liquid; Doxorubicin; Drug Design; Endocytosis; Flow Cytometry; Humans; Inhibitory Concentration 50; Microscopy, Fluorescence; Models, Chemical; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2009 |
The novel anti-Propionibacterium acnes compound, Sargafuran, found in the marine brown alga Sargassum macrocarpum.
Topics: Anti-Bacterial Agents; Bacteria; Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media; Fibroblasts; Furans; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Conformation; Propionibacterium acnes; Sargassum; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Terpenes; Tetrazolium Salts; Thiazoles | 2009 |
5-hydroxytryptophan acts on the mitogen-activated protein kinase extracellular-signal regulated protein kinase pathway to modulate cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 cells.
Topics: 5-Hydroxytryptophan; Analgesics, Non-Narcotic; Animals; Blotting, Western; Cyclooxygenase 2; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase Type II; Pain Measurement; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
N/P ratio significantly influences the transfection efficiency and cytotoxicity of a polyethylenimine/chitosan/DNA complex.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Chromatography, Gel; DNA; Electrochemistry; Green Fluorescent Proteins; HeLa Cells; Humans; Luciferases; Particle Size; Plasmids; Polyethyleneimine; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Kaempferol attenuates 2-deoxy-d-ribose-induced oxidative cell damage in MC3T3-E1 osteoblastic cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Calcification, Physiologic; Calcium; Collagen; Deoxyribose; Kaempferols; Lipid Peroxidation; Malondialdehyde; Mice; Osteoblasts; Osteoprotegerin; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2009 |
Design and synthesis of a gossypol derivative with improved antitumor activities.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colony-Forming Units Assay; Drug Screening Assays, Antitumor; Gossypol; Humans; Indicators and Reagents; Models, Molecular; Tetrazolium Salts; Thiazoles | 2009 |
Phenotypic diversity of infectious red sea bream iridovirus isolates from cultured fish in Japan.
Topics: Animals; Capsid Proteins; Cell Survival; Cells, Cultured; Cluster Analysis; DNA Virus Infections; DNA, Viral; Fishes; Iridovirus; Japan; Molecular Sequence Data; Phylogeny; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Survival Analysis; Tetrazolium Salts; Thiazoles; Vaccines, Inactivated; Viral Vaccines; Virulence | 2009 |
Cellular toxicity of nanogenomedicine in MCF-7 cell line: MTT assay.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coloring Agents; Humans; Nanostructures; Spectrophotometry; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2009 |
Cytotoxic effects of different concentrations of a carbamide peroxide bleaching gel on odontoblast-like cells MDPC-23.
Topics: Carbamide Peroxide; Cell Line; Dental Enamel; Dose-Response Relationship, Drug; Drug Combinations; Gels; Humans; Hydrogen Peroxide; Microscopy, Electron, Scanning; Odontoblasts; Peroxides; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Bleaching; Tooth Discoloration; Urea | 2009 |
Herba leonurine attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells.
Topics: Animals; Apoptosis; Benzimidazoles; Bisbenzimidazole; Calcium; Carbocyanines; Cardiotonic Agents; Cell Nucleus; Cell Survival; Cells, Cultured; Coloring Agents; Doxorubicin; Fluorescent Dyes; Gallic Acid; Heart Ventricles; Malondialdehyde; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Rats; Tetrazolium Salts; Thiazoles | 2009 |
Rutin from Lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects H9c2 cells against hydrogen peroxide-mediated injury via ERK1/2 and PI3K/Akt signals in vitro.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Hemodynamics; Hydrogen Peroxide; In Situ Nick-End Labeling; Lonicera; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Reperfusion Injury; Oxidants; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rutin; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Neuroprotective effects of statins in an in vitro model of Alzheimer's disease.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Calcium; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; In Situ Nick-End Labeling; Lovastatin; Neurons; Neuroprotective Agents; Oncogene Protein v-akt; Peptide Fragments; Rats; Rats, Wistar; Reactive Oxygen Species; Simvastatin; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
In vitro effects of histone deacetylase inhibitors and mitomycin C on tenon capsule fibroblasts and conjunctival melanoma cells.
Topics: Apoptosis; Butyrates; Cell Cycle; Cell Proliferation; Cell Survival; Conjunctival Neoplasms; Connective Tissue Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Melanoma; Mitomycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2009 |
Targeted antitumoral dehydrocrotonin nanoparticles with L-ascorbic acid 6-stearate.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Ascorbic Acid; Caspases; Cell Line, Tumor; Chromatography, Thin Layer; Coloring Agents; Diterpenes, Clerodane; Drug Delivery Systems; Electrochemistry; Excipients; Flow Cytometry; HL-60 Cells; Humans; Kinetics; Nanoparticles; Particle Size; Spectrophotometry, Ultraviolet; Suspensions; Tetrazolium Salts; Thiazoles; Trypan Blue | 2009 |
Three-dimensional gastric cancer cell culture using nanofiber scaffold for chemosensitivity test.
Topics: Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Microscopy, Electron, Scanning; Nanostructures; Polyesters; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2009 |
Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.
Topics: Anemarrhena; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Interleukin-6; Lipopolysaccharides; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Plant Roots; Reverse Transcriptase Polymerase Chain Reaction; RNA; Saponins; Signal Transduction; Tetrazolium Salts; Thiazoles; Triterpenes; Tumor Necrosis Factor-alpha | 2009 |
Synthesis and screening of 1-methyl-4-substituted benzoyl piperazides against adult Setaria digitata for antifilarial activity.
Topics: Animals; Drug Evaluation, Preclinical; Filaricides; Filarioidea; Humans; Locomotion; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Viability; Piperazines; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2009 |
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells.
Topics: Adenosine; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cell Proliferation; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Etodolac; Humans; Indomethacin; Inhibitory Concentration 50; Ketoprofen; Kinetics; Mefenamic Acid; Muscle, Smooth, Vascular; Piroxicam; Sulindac; Temperature; Tetrazolium Salts; Thiazoles; Thioinosine | 2009 |
Glioma-associated endothelial cells are chemoresistant to temozolomide.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Temozolomide; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2009 |
Protective effect of memantine against Doxorubicin toxicity in primary neuronal cell cultures: influence a development stage.
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Brain; Calcium; Caspase 3; Caspase 8; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Embryo, Mammalian; Excitatory Amino Acid Antagonists; L-Lactate Dehydrogenase; Memantine; Mice; Neurons; Neuroprotective Agents; Oligopeptides; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Apoptosis; Brain; Cell Line, Tumor; Dexamethasone; Dose-Response Relationship, Drug; Glioblastoma; Humans; In Situ Nick-End Labeling; Indans; Monoamine Oxidase; Neuroblastoma; Neuroprotective Agents; Selegiline; Tetrazolium Salts; Thiazoles | 2009 |
Ectopic bone formation in adipose-derived stromal cell-seeded osteoinductive calcium phosphate scaffolds.
Topics: Adipose Tissue; Animals; Biocompatible Materials; Bone and Bones; Bone Development; Calcium Phosphates; Dogs; Male; Osteogenesis; Phosphates; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; X-Ray Microtomography | 2010 |
Thrombin enhances glioma growth.
Topics: Animals; Anticoagulants; Arginine; Behavior, Animal; Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Glioma; Hemostatics; Male; Neoplasm Transplantation; Pipecolic Acids; Rats; Rats, Inbred F344; Sulfonamides; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors | 2008 |
Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Damage; Female; Gene Expression; Genes, bcl-2; Genes, p53; Humans; NF-kappa B; Phaeophyceae; Phloroglucinol; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Evaluation of Tualang honey as a supplement to fetal bovine serum in cell culture.
Topics: Animals; Cattle; Cell Line; Cell Proliferation; Cells, Cultured; Chromosome Aberrations; Coloring Agents; Culture Media; Gene Expression; Honey; Humans; Mitotic Index; Osteoblasts; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serum; Tetrazolium Salts; Thiazoles | 2009 |
Nonmyofilament-associated troponin T fragments induce apoptosis.
Topics: Actin Cytoskeleton; Animals; Apoptosis; Blotting, Western; Cells, Cultured; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Mice; Myoblasts; Nucleosomes; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Transfection; Troponin T | 2009 |
MTT assays cannot be utilized to study the effects of STI571/Gleevec on the viability of solid tumor cell lines.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Melanoma; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Tetrazolium Salts; Thiazoles | 2009 |
Biologic assessment of antiseptic mouthwashes using a three-dimensional human oral mucosal model.
Topics: Cell Proliferation; Coloring Agents; Drug Combinations; Ethanol; Humans; Interleukin-1beta; Microscopy, Electron, Transmission; Models, Biological; Mouth Mucosa; Mouthwashes; Salicylates; Terpenes; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Survival | 2009 |
Neuroprotective effects of yokukansan, a traditional Japanese medicine, on glutamate-mediated excitotoxicity in cultured cells.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Cell Death; Cells, Cultured; Competitive Bidding; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamic Acid; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tetrazolium Salts; Thiamine Deficiency; Thiazoles | 2009 |
The natural diterpenoid ovatodiolide induces cell cycle arrest and apoptosis in human oral squamous cell carcinoma Ca9-22 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Diterpenes; Enzyme Activation; Genes, p53; Humans; Mouth Neoplasms; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
Comparison of calcium and silicate cement and mineral trioxide aggregate biologic effects and bone markers expression in MG63 cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Biocompatible Materials; Biomarkers; Blotting, Western; Calcium Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen Type I; Colorimetry; Coloring Agents; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Humans; Integrin-Binding Sialoprotein; Materials Testing; Mitogen-Activated Protein Kinases; Osteoblasts; Osteopontin; Oxides; Reverse Transcriptase Polymerase Chain Reaction; Root Canal Filling Materials; Sialoglycoproteins; Silicates; Tetrazolium Salts; Thiazoles; Time Factors; X-Ray Diffraction | 2009 |
Hypoglycaemic activity of four plant extracts traditionally used in South Africa for diabetes.
Topics: 3T3 Cells; alpha-Amylases; Animals; Cells, Cultured; Coloring Agents; Diabetes Mellitus; Dose-Response Relationship, Drug; Ferrocyanides; Glucose; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Liver; Medicine, African Traditional; Mice; Plant Extracts; Plants, Medicinal; South Africa; Tetrazolium Salts; Thiazoles | 2009 |
Inhibitory effects of chitooligosaccharides on tumor growth and metastasis.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Chitosan; Coloring Agents; Gelatin; Humans; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, SCID; Molecular Weight; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Tetrazolium Salts; Thiazoles | 2009 |
An in vitro study of bare and poly(ethylene glycol)-co-fumarate-coated superparamagnetic iron oxide nanoparticles: a new toxicity identification procedure.
Topics: Adsorption; Animals; Cell Line; Cell Survival; Culture Media; Ferric Compounds; Fumarates; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Polyethylene Glycols; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Proteome changes related to the anti-cancer activity of HT29 cells by the treatment of ginsenoside Rd.
Topics: Antineoplastic Agents, Phytogenic; Caspase 3; DNA Fragmentation; DNA Replication; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Ginsenosides; HT29 Cells; Humans; Hydrolysis; Image Interpretation, Computer-Assisted; Indicators and Reagents; Proteome; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Trypsin | 2009 |
Error assessment in recombinant baculovirus titration: evaluation of different methods.
Topics: Analysis of Variance; Animals; Baculoviridae; Cell Line; Cell Size; Endpoint Determination; Flow Cytometry; Indicators and Reagents; Oxazines; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Spodoptera; Tetrazolium Salts; Thiazoles; Titrimetry; Viral Plaque Assay; Xanthenes | 2009 |
Proteome response to ochratoxin A-induced apoptotic cell death in mouse hippocampal HT22 cells.
Topics: Analysis of Variance; Animals; Apoptosis; Calcium Channel Blockers; Cell Line, Transformed; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Hippocampus; Humans; L-Lactate Dehydrogenase; Mice; Mitochondria; Neuroblastoma; Nucleophosmin; Ochratoxins; Proteome; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles | 2009 |
Constitutive release of cytokines by human oral keratinocytes in an organotypic culture.
Topics: Cell Survival; Coloring Agents; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Humans; In Situ Hybridization; Interleukin-1alpha; Interleukin-6; Interleukin-8; Interleukins; Keratinocytes; Mouth Mucosa; Organ Culture Techniques; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering; Tissue Scaffolds; Vascular Endothelial Growth Factor A | 2009 |
A novel WD-40 repeat protein WDR26 suppresses H2O2-induced cell death in neural cells.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Antigens, Neoplasm; Caspase 3; Cell Death; Cell Line, Tumor; DNA, Single-Stranded; Electrophoretic Mobility Shift Assay; Flow Cytometry; Humans; Hydrogen Peroxide; Neuroblastoma; Oxidants; Oxidative Stress; Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation | 2009 |
Bilirubin as a determinant for altered neurogenesis, neuritogenesis, and synaptogenesis.
Topics: Analysis of Variance; Animals; Antioxidants; Bilirubin; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Green Fluorescent Proteins; Hippocampus; Mice; Nerve Tissue Proteins; Neurites; Neurogenesis; Neurons; Synapses; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2009 |
Doxorubicin augments rAAV-2 transduction in rat neuronal cells.
Topics: Animals; Capsid Proteins; Coloring Agents; Dependovirus; Doxorubicin; Fluorescent Dyes; In Situ Nick-End Labeling; Indicators and Reagents; Luciferases; Microscopy, Confocal; Neostriatum; Neurons; PC12 Cells; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2009 |
PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models.
Topics: Analysis of Variance; Animals; Annexin A5; Antineoplastic Agents; bcl-2-Associated X Protein; Brain Neoplasms; Bromodeoxyuridine; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioma; Humans; Ligands; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Pioglitazone; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Rats; Retinoid X Receptor gamma; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transfection; Tretinoin; Tumor Stem Cell Assay | 2009 |
Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Crocus; DNA Fragmentation; Female; Flow Cytometry; Humans; Indicators and Reagents; Plant Extracts; Tetrazolium Salts; Thiazoles | 2009 |
Alpha-tomatine inactivates PI3K/Akt and ERK signaling pathways in human lung adenocarcinoma A549 cells: effect on metastasis.
Topics: Carbohydrate Sequence; Cell Line, Tumor; Cell Movement; Cell Nucleus; Coloring Agents; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Signal Transduction; Tetrazolium Salts; Thiazoles; Tomatine; Urokinase-Type Plasminogen Activator; Wound Healing | 2009 |
Morphological and biochemical analysis of human cardiac valve allografts after an increment of the cryostorage temperature.
Topics: Animals; Aorta; Collagen; Colorimetry; Coloring Agents; Cryopreservation; Fibroblasts; Heart Valves; Humans; Immunohistochemistry; Organ Preservation; Swine; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Osteogenic induction and 1,25-dihydroxyvitamin D3 oppositely regulate the proliferation and expression of RANKL and the vitamin D receptor of human periodontal ligament cells.
Topics: Adolescent; Calcification, Physiologic; Calcitriol; Calcium Channel Agonists; Cell Proliferation; Cells, Cultured; Child; Coloring Agents; Down-Regulation; Humans; Keratins; Osteoclasts; Osteogenesis; Osteoprotegerin; Periodontal Ligament; RANK Ligand; Receptors, Calcitriol; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Up-Regulation; Vimentin; Young Adult | 2009 |
Effects of perfluorooctanoate and perfluorooctane sulfonate exposure on hepatoma Hep G2 cells.
Topics: Alkanesulfonic Acids; Apoptosis; Caprylates; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Interactions; Environmental Pollutants; Fluorocarbons; Gene Expression; Genes, bcl-2; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53 | 2009 |
In vitro toxicity of MTA compared with other primary teeth pulpotomy agents.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Calcium Compounds; Calcium Hydroxide; Cell Membrane; Cell Proliferation; Cell Survival; Coloring Agents; Drug Combinations; Ferric Compounds; Formocresols; Lethal Dose 50; Mice; Mitochondria; Neutral Red; Oxides; Pulpotomy; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles | 2009 |
Biofilm formation by Candida species on silicone surfaces and latex pacifier nipples: an in vitro study.
Topics: Biofilms; Candida; Cell Adhesion; Fomites; Humans; Infant; Latex; Microscopy, Electron, Scanning; Pacifiers; Silicones; Surface Properties; Tetrazolium Salts; Thiazoles | 2009 |
Fibroblast growth factor 9 prevents MPP+-induced death of dopaminergic neurons and is involved in melatonin neuroprotection in vivo and in vitro.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Antibodies; Cell Death; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 9; Fibroblast Growth Factors; Glial Fibrillary Acidic Protein; Herbicides; Male; Melatonin; Mesencephalon; Microtubule-Associated Proteins; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase | 2009 |
Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatment.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Homocysteine; Mass Spectrometry; Mitosis; Myocytes, Smooth Muscle; Oxidative Stress; Plant Extracts; Plant Roots; Protein Carbonylation; Proteomics; Rats; Reactive Oxygen Species; Salvia miltiorrhiza; Tetrazolium Salts; Thiazoles | 2009 |
Stearic acid-induced cardiac lipotoxicity is independent of cellular lipid and is mitigated by the fatty acids oleic and capric acid but not by the PPAR agonist troglitazone.
Topics: Animals; Cell Death; Chick Embryo; Chromans; Decanoic Acids; Lipid Metabolism; Myocytes, Cardiac; Oleic Acids; Stearic Acids; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2009 |
Design, synthesis and evaluation of tetrahydroisoquinolines as new kinesin spindle protein inhibitors.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Kinesins; Models, Molecular; Molecular Conformation; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles | 2009 |
Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly(ethylene glycol) and polyphosphoester.
Topics: Biocompatible Materials; Cell Line; Coloring Agents; Esters; Gold; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Nanoparticles; Nanostructures; Nanotechnology; Polyethylene Glycols; Polymers; Temperature; Tetrazolium Salts; Thiazoles | 2009 |
The effect of doxycycline hyclate, chlorhexidine gluconate, and minocycline hydrochloride on osteoblastic proliferation and differentiation in vitro.
Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biomarkers; Cell Adhesion; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Chlorhexidine; Coloring Agents; Doxycycline; Drug Carriers; Female; Gels; Humans; Male; Microscopy, Electron, Scanning; Microspheres; Middle Aged; Minocycline; Osteoblasts; Pseudopodia; Tetrazolium Salts; Thiazoles; Trypan Blue | 2009 |
Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2009 |
Anabolic effects of low-intensity pulsed ultrasound on human gingival fibroblasts.
Topics: Alkaline Phosphatase; Biomarkers; Cell Proliferation; Cell Survival; Chromogenic Compounds; Collagen Type I; Coloring Agents; Dental Cementum; DNA; Feasibility Studies; Fibroblasts; Gingiva; Humans; Odontoblasts; Osteogenesis; Osteopontin; Periodontal Ligament; Proliferating Cell Nuclear Antigen; Tetrazolium Salts; Thiazoles; Time Factors; Ultrasonics; Up-Regulation | 2009 |
Targeting epidermal growth factor receptor 1 signaling in human thyroid-stimulating hormone-independent thyroid carcinoma FRO cells results in a more chemosensitive and less angiogenic phenotype.
Topics: Antineoplastic Agents; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Microscopy, Confocal; Neovascularization, Pathologic; Phenotype; RNA, Neoplasm; S Phase; Signal Transduction; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Thyrotropin | 2009 |
Anti-inflammatory effect of coumarins isolated from Corydalis heterocarpa in HT-29 human colon carcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Survival; Coloring Agents; Corydalis; Coumarins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Furocoumarins; HT29 Cells; Humans; Inflammation Mediators; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Panax ginseng C.A. Meyer modulates the levels of MMP3 in S12 murine articular cartilage cell line.
Topics: Blotting, Western; Cartilage, Articular; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Collagen Type II; Coloring Agents; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Ginsenosides; Indicators and Reagents; Interleukin-1beta; Korea; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Medicine, East Asian Traditional; p38 Mitogen-Activated Protein Kinases; Panax; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2009 |
Identification of the protein components displaying immunomodulatory activity in aged garlic extract.
Topics: Animals; Chromatography, Ion Exchange; Coloring Agents; Electrophoresis, Polyacrylamide Gel; Garlic; Glycoproteins; Hemagglutination Tests; Immunologic Factors; Mice; Mice, Inbred BALB C; Plant Extracts; Plant Proteins; Protein Binding; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2009 |
In vitro cytotoxicity of orthodontic primers.
Topics: Animals; BALB 3T3 Cells; Cell Death; Cell Membrane; Cell Survival; Coloring Agents; Dentin-Bonding Agents; Dose-Response Relationship, Drug; Ethanol; Flow Cytometry; Materials Testing; Methacrylates; Mice; Mitochondria; Necrosis; Oxidoreductases; Resin Cements; Tetrazolium Salts; Thiazoles | 2009 |
Improved adherence and spreading of Saos-2 cells on polypropylene surfaces achieved by surface texturing and carbon nitride coating.
Topics: Biocompatible Materials; Carbon; Cell Adhesion; Cell Line, Tumor; Humans; Hydrophobic and Hydrophilic Interactions; Lasers; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Nitriles; Nitrogen; Osteoblasts; Polypropylenes; Silicon; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Mitochondrial Na+/Ca2+-exchanger blocker CGP37157 protects against chromaffin cell death elicited by veratridine.
Topics: Animals; Calcium Channels; Calcium Signaling; Cattle; Cell Death; Cells, Cultured; Chromaffin Cells; Clonazepam; Coloring Agents; Cytochromes c; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Patch-Clamp Techniques; Reactive Oxygen Species; Sodium Channels; Sodium-Calcium Exchanger; Tetrazolium Salts; Thiazepines; Thiazoles; Veratridine | 2009 |
Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells.
Topics: Animals; Apoptosis; Benzothiazoles; Cell Death; Dopamine Agonists; Dopamine Antagonists; Endoplasmic Reticulum; L-Lactate Dehydrogenase; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Pramipexole; Rats; Spiperone; Tetrazolium Salts; Thiazoles; Tunicamycin | 2009 |
Design, synthesis and biological evaluation of 2H-benzo[b][1,4] oxazine derivatives as hypoxia targeted compounds for cancer therapeutics.
Topics: Antineoplastic Agents; Benzoxazines; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitory Concentration 50; Models, Chemical; Neoplasms; Oxazines; Polymerase Chain Reaction; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A | 2009 |
Neuronal response of peroxisomal and peroxisome-related proteins to chronic and acute Abeta injury.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Benzothiazoles; Cell Survival; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Gene Expression Regulation, Enzymologic; Glutathione S-Transferase pi; Indoles; Insulysin; Nerve Tissue Proteins; Neurons; Peptide Fragments; Peroxidases; PPAR alpha; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Bioactive responses of Hep-G2 cells to soyasaponin extracts differs with respect to extraction conditions.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Hepatocytes; Humans; Liver Neoplasms; Oleanolic Acid; Plant Extracts; Saponins; Soybean Proteins; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2009 |
Synthesis and antimultidrug resistance evaluation of icariin and its derivatives.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonoids; Humans; Inhibitory Concentration 50; Models, Chemical; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake.
Topics: Analysis of Variance; Animals; Atorvastatin; Cell Death; Complex Mixtures; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Mice; Oncogene Protein v-akt; Phosphorylation; Pyrroles; Quinolinic Acid; Seizures; Tetrazolium Salts; Thiazoles; Tritium | 2009 |
Nitric oxide-mediated toxicity in paraquat-exposed SH-SY5Y cells: a protective role of 7-nitroindazole.
Topics: Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Death; Cell Line, Tumor; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Herbicides; Humans; Indazoles; NADPH Dehydrogenase; Neuroblastoma; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nuclear Proteins; Paraquat; Peroxynitrous Acid; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2009 |
Aphyllin, the first isoferulic acid glycoside and other phenolics from Tamarix aphylla flowers.
Topics: Antioxidants; Biphenyl Compounds; Cell Differentiation; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cinnamates; Coloring Agents; Coumaric Acids; Flowers; Free Radical Scavengers; Glucosides; Humans; Keratinocytes; Methanol; Phenols; Picrates; Plant Extracts; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tamaricaceae; Tetrazolium Salts; Thiazoles | 2009 |
A mechanistically relevant cytotoxicity assay based on the detection of cellular GFP.
Topics: Animals; Biological Assay; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Coloring Agents; Cytotoxins; Flow Cytometry; Green Fluorescent Proteins; Image Cytometry; Image Processing, Computer-Assisted; Ribosomes; Ricin; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles; Transfection; Vero Cells | 2009 |
The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells.
Topics: Animals; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Isoflavones; Leukemia, Myeloid, Acute; Mice; Oxidation-Reduction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2009 |
Hydrogen sulfide inhibits MPP(+)-induced apoptosis in PC12 cells.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Survival; Cytoprotection; Flow Cytometry; Hydrogen Sulfide; Matrix Metalloproteinases; Membrane Potential, Mitochondrial; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2009 |
Intracellular oxidative stress and cadmium ions release induce cytotoxicity of unmodified cadmium sulfide quantum dots.
Topics: Animals; Biomimetics; Cadmium Compounds; Cells, Cultured; Cricetinae; Cricetulus; Glutathione; Lung; Nanoparticles; Oxidative Stress; Quantum Dots; Reactive Oxygen Species; Spectrophotometry, Atomic; Sulfides; Tetrazolium Salts; Thiazoles | 2009 |
Paeoniflorin protects RAW 264.7 macrophages from LPS-induced cytotoxicity and genotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Cell Line; Cell Survival; Comet Assay; Dinoprostone; DNA Breaks; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Glucosides; Lipopolysaccharides; Macrophages; Mice; Monoterpenes; Nitric Oxide; Tetrazolium Salts; Thiazoles | 2009 |
Relationship between microstructure, cytotoxicity and corrosion properties of a Cu-Al-Ni shape memory alloy.
Topics: Alloys; Aluminum; Animals; Apoptosis; Biocompatible Materials; Cell Survival; Copper; Corrosion; Dental Alloys; Male; Mice; Nickel; Oxygen; Rats; Spleen; Surface Properties; Tetrazolium Salts; Thiazoles; Thymus Gland | 2010 |
Inhibition of mitochondria-dependent apoptosis by 635-nm irradiation in sodium nitroprusside-treated SH-SY5Y cells.
Topics: Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Humans; Light; Mitochondria; Neurons; Nitric Oxide; Nitroprusside; Peroxynitrous Acid; Superoxides; Tetrazolium Salts; Thiazoles | 2009 |
Prokaryotic expression, purification and functional characterization of human FHL3.
Topics: Cell Line; Cell Proliferation; Cloning, Molecular; DNA, Complementary; Escherichia coli; Gene Expression; Gene Library; Hepatocytes; Humans; Inclusion Bodies; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Recombinant Proteins; Spleen; Tetrazolium Salts; Thiazoles | 2009 |
A dual-fluorescence high-throughput cell line system for probing multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescence; Genotype; Humans; Laser Scanning Cytometry; Microscopy, Confocal; Mitoxantrone; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Selective NTPDase2 expression modulates in vivo rat glioma growth.
Topics: Adenosine Triphosphatases; Animals; Apyrase; Bacterial Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Fluorescent Dyes; Glioma; Immunohistochemistry; Luminescent Proteins; Models, Biological; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Vascular Endothelial Growth Factor A | 2009 |
Cytogenotoxicity induced by PBDE-47 combined with PCB153 treatment in SH-SY5Y cells.
Topics: Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Environmental Pollutants; Halogenated Diphenyl Ethers; Humans; Micronucleus Tests; Polychlorinated Biphenyls; Tetrazolium Salts; Thiazoles | 2010 |
The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Glioma; Humans; Membrane Potentials; Microscopy, Fluorescence; Mitochondrial Membranes; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2009 |
Expression of CXCR4 in oral squamous cell carcinoma: correlations with clinicopathology and pivotal role of proliferation.
Topics: Adult; Aged; Antibodies, Monoclonal; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL12; Coloring Agents; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Immunohistochemistry; Lymphatic Metastasis; Male; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Receptors, CXCR4; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Oligomycin induced the proteasomal degradation of cyclin D1 protein.
Topics: Adenoviridae; Blotting, Western; Cell Line; Cyclin D1; Flow Cytometry; Gene Expression; Genes, bcl-1; Genetic Vectors; Humans; Indicators and Reagents; Oligomycins; Plasmids; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Chondrogenesis on BMP-6 loaded chitosan scaffolds in stationary and dynamic cultures.
Topics: Animals; Bone Morphogenetic Protein 6; Cell Survival; Chitosan; Chondrocytes; Chondrogenesis; Collagen Type II; DNA; Glycosaminoglycans; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2009 |
Guanosine-5'-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition.
Topics: Animals; Cell Death; Cell Survival; Coloring Agents; Dipyridamole; Excitatory Amino Acid Agonists; Glutamic Acid; Guanosine Monophosphate; Hippocampus; Indicators and Reagents; Male; Organ Culture Techniques; Propidium; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Purinergic P1; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxicity and estrogenicity of Invisalign appliances.
Topics: Adenocarcinoma; Benzhydryl Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Materials; Endocrine Disruptors; Estradiol; Estrogens, Non-Steroidal; Female; Fibroblasts; Gingiva; Humans; Materials Testing; Orthodontic Appliance Design; Phenols; Receptors, Estrogen; Sodium Chloride; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Movement Techniques | 2009 |
Induction of cells differentiation and ABC transporters expression by a myco-estrogen, zearalenone, in human choriocarcinoma cell line (BeWo).
Topics: ATP-Binding Cassette Transporters; Cell Differentiation; Cell Line, Tumor; Cell Survival; Choriocarcinoma; Colforsin; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Estrogens, Non-Steroidal; Female; Fluorescent Antibody Technique, Indirect; Humans; Pregnancy; Tetrazolium Salts; Thiazoles; Time Factors; Trophoblasts; Zearalenone | 2009 |
Influence of ADAM28 on biological characteristics of human dental follicle cells.
Topics: ADAM Proteins; Alkaline Phosphatase; Annexin A5; Apoptosis; Cell Cycle; Cell Differentiation; Cell Proliferation; Child; Collagen Type III; Coloring Agents; Dental Sac; Disintegrins; Enzyme Inhibitors; Extracellular Matrix Proteins; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Integrin-Binding Sialoprotein; Membrane Glycoproteins; Oligodeoxyribonucleotides, Antisense; Osteopontin; Phosphoproteins; Plasmids; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts, dermal prekeratinocytes, preadipocytes, and maxillofacial osteoblasts in primary cultures.
Topics: Adipocytes; Alkaline Phosphatase; Biomarkers; Blood Platelets; Calcification, Physiologic; Cell Count; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniques; Coloring Agents; Dose-Response Relationship, Drug; Fibrin; Fibroblasts; Gingiva; Humans; Keratinocytes; Leukocytes; Male; Mandible; Microscopy, Electron, Scanning; Middle Aged; Osteoblasts; Skin; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Cytotoxic, mutagenic and genotoxic effects of new anti-T. cruzi 5-phenylethenylbenzofuroxans. Contribution of phase I metabolites on the mutagenicity induction.
Topics: Animals; Benzoxazoles; Biotransformation; Cell Survival; Coloring Agents; Comet Assay; Cricetinae; Cytosol; Female; Humans; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Rats, Wistar; Salmonella typhimurium; Tetrazolium Salts; Thiazoles; Trypanocidal Agents | 2009 |
Blockade of connexin 43 hemichannels reduces neointima formation after vascular injury by inhibiting proliferation and phenotypic modulation of smooth muscle cells.
Topics: Animals; Carbenoxolone; Carotid Artery Injuries; Cell Proliferation; Coloring Agents; Connexin 43; Endothelium, Vascular; Fluorescence Recovery After Photobleaching; Fluorescent Antibody Technique, Indirect; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptides; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection; Tunica Intima | 2009 |
INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors.
Topics: Adenoviridae; Animals; Antiviral Agents; beta-Galactosidase; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Ganciclovir; Gene Expression Regulation, Neoplastic; Genetic Therapy; Genetic Vectors; Humans; Male; Mice; Mice, Nude; Neuroectodermal Tumors, Primitive; Promoter Regions, Genetic; Repressor Proteins; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Viral Proteins | 2009 |
Development and characterization of rhVEGF-loaded poly(HEMA-MOEP) coatings electrosynthesized on titanium to enhance bone mineralization and angiogenesis.
Topics: Biocompatible Materials; Calcification, Physiologic; Calcium; Cell Line, Tumor; Cell Survival; Humans; Methacrylates; Neovascularization, Physiologic; Osteoblasts; Phosphorus; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Titanium; Vascular Endothelial Growth Factor A | 2010 |
Cytotoxicity of polymerized resin cements on human dental pulp cells in vitro.
Topics: Adolescent; Adult; Boron Compounds; Cell Count; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Child; Coloring Agents; Culture Media, Serum-Free; Dental Cements; Dental Pulp; Humans; Materials Testing; Methacrylates; Methylmethacrylates; Polymers; Resin Cements; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2009 |
Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Chemokine CCL19; Chromones; Cisplatin; Coloring Agents; Enzyme Inhibitors; Flow Cytometry; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptors, CCR7; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2010 |
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Topics: Animals; Blood Pressure; Brain Infarction; Cells, Cultured; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Neuroprotective Agents; Nitrites; Nitrogen Oxides; Oxidative Stress; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
The effects of fluoride on cell migration, cell proliferation, and cell metabolism in GH4C1 pituitary tumour cells.
Topics: Actins; Animals; Blotting, Western; Cell Adhesion; Cell Count; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cytoskeleton; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorides; Neoplasm Proteins; Phosphorylation; Prolactin; Rats; Tetrazolium Salts; Thiazoles | 2009 |
Endogenous Aβ causes cell death via early tau hyperphosphorylation.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antibodies; Axonal Transport; Caspase 3; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Hippocampus; Humans; Microtubules; Nerve Growth Factor; Neurons; Phosphorylation; Pregnancy; Protein Binding; Rats; Rats, Wistar; Signal Transduction; tau Proteins; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2: I. Taxonomy, fermentation, isolation and biological properties.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Cell Line, Tumor; Coloring Agents; Drug Synergism; Fermentation; Humans; Imipenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oryza; Penicillium; Tetrazolium Salts; Thiazoles | 2009 |
In-vitro effects of the tyrosine kinase inhibitor imatinib on glioblastoma cell proliferation.
Topics: Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Size; Cell Survival; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Flow Cytometry; Glioblastoma; Humans; Imatinib Mesylate; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Tetrazolium Salts; Thiazoles | 2010 |
Comparison of motility, recovery, and methyl-thiazolyl-tetrazolium reduction assays for use in screening plant products for anthelmintic activity.
Topics: Animals; Anthelmintics; Caenorhabditis elegans; Combretaceae; Drug Evaluation, Preclinical; Locomotion; Plant Extracts; Survival Analysis; Tetrazolium Salts; Thiazoles | 2009 |
An effort to test the embryotoxicity of benzene, toluene, xylene, and formaldehyde to murine embryonic stem cells using airborne exposure technique.
Topics: Air Pollutants, Occupational; Air Pollution, Indoor; Algorithms; Animals; Atmosphere Exposure Chambers; Cells, Cultured; Coloring Agents; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Embryonic Stem Cells; Mice; Solvents; Tetrazolium Salts; Thiazoles | 2009 |
In vitro comparison of the cytotoxicity of acetal resin, heat-polymerized resin, and auto-polymerized resin as denture base materials.
Topics: Animals; Cell Line; Cell Survival; Coloring Agents; Culture Media; Dental Materials; Dentures; Fibroblasts; Formaldehyde; Mice; Polymers; Resins, Synthetic; Tetrazolium Salts; Thiazoles | 2009 |
Comparison of in vitro hormone activities of selected phthalates using reporter gene assays.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Cell Line; Chlorocebus aethiops; Coloring Agents; Dibutyl Phthalate; Diethylhexyl Phthalate; Endocrine Disruptors; Estradiol; Genes, Reporter; Hormones; Ligands; Mice; Phthalic Acids; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Thyroid Hormone; Tetrazolium Salts; Thiazoles; Triiodothyronine | 2009 |
Cilnidipine mediates a neuroprotective effect by scavenging free radicals and activating the phosphatidylinositol 3-kinase pathway.
Topics: Analysis of Variance; Animals; Apoptosis; Calcium Channel Blockers; Cell Differentiation; Cell Survival; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Indoles; Neurons; omega-Conotoxins; Oxidants; Oxidative Stress; PC12 Cells; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Line, Transformed; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation; Herbicides; Hydrogen Peroxide; Mesencephalon; Neurons; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Paraquat; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tyrosine; Vitamin E | 2009 |
Induction of apoptotic cell death preferentially in reactive astrocytes by concanavalin A.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Cell Survival; Cells, Cultured; Concanavalin A; Glycoproteins; Mannose; Neuroglia; Neurons; Rats; Rats, Wistar; Regeneration; Tetrazolium Salts; Thiazoles | 2009 |
The antioxidant, taurine reduced lipopolysaccharide (LPS)-induced generation of ROS, and activation of MAPKs and Bax in cultured pneumocytes.
Topics: Alveolar Epithelial Cells; Antioxidants; bcl-2-Associated X Protein; Calcium Signaling; Cell Survival; Cells, Cultured; Coloring Agents; Enzyme Activation; Fibroblasts; Humans; Lipopolysaccharides; Lung; Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Taurine; Tetrazolium Salts; Thiazoles | 2009 |
A plasmacytoid dendritic cell (CD123+/CD11c-) based assay system to predict contact allergenicity of chemicals.
Topics: Allergens; Animal Testing Alternatives; Animals; Antibodies, Monoclonal; Biological Assay; CD11 Antigens; Cells, Cultured; Coloring Agents; Cosmetics; Dendritic Cells; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fetal Blood; Flow Cytometry; Humans; Interleukin-3 Receptor alpha Subunit; Lipopolysaccharides; Local Lymph Node Assay; Mice; Pharmaceutical Vehicles; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 2009 |
In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Cells, Cultured; Inhibitory Concentration 50; Mice; Microscopy, Electron, Transmission; Myocytes, Cardiac; Tetrazolium Salts; Thiazoles; Trypanosoma cruzi | 2009 |
Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Central Nervous System Depressants; Coloring Agents; Culture Media, Conditioned; Ethanol; Female; Hippocampus; Immunohistochemistry; Muscarinic Agonists; Neurites; Neurons; Parasympathetic Nervous System; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Intensity and duration of chronic ethanol exposure is critical for subsequent escalation of voluntary ethanol drinking in mice.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Carbachol; Cells, Cultured; Central Nervous System Depressants; Coloring Agents; Culture Media, Conditioned; Ethanol; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Immunohistochemistry; Male; Mice; Muscarinic Agonists; Neurons; Pregnancy; Protein Kinase C; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazolium Salts; Thiazoles | 2009 |
Alcoholism and dampened temporal limbic activation to emotional faces.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Carbachol; Cells, Cultured; Central Nervous System Depressants; Culture Media, Conditioned; Ethanol; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Immunohistochemistry; Muscarinic Agonists; Neurons; Pregnancy; Protein Kinase C; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazolium Salts; Thiazoles | 2009 |
Early effects of lasonolide a on pancreatic cancer cells.
Topics: Actins; Animals; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytoskeleton; Enzyme Activation; Humans; L-Lactate Dehydrogenase; Macrolides; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Porifera; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Tetrazolium Salts; Thiazoles; Tubulin | 2009 |
Epirubicin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Delivery Systems; Epirubicin; Female; Glioma; Humans; Polymers; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Immunostimulatory activities of a low molecular weight antitumoral polysaccharide isolated from Agaricus blazei Murill (LMPAB) in Sarcoma 180 ascitic tumor-bearing mice.
Topics: Adjuvants, Immunologic; Agaricus; Animals; Cell Proliferation; Coloring Agents; Cytokines; Female; Immunity, Cellular; Immunohistochemistry; Indicators and Reagents; Interferon-gamma; Interleukin-12; Interleukin-18; Killer Cells, Natural; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Polysaccharides; Sarcoma 180; Spleen; Tetrazolium Salts; Thiazoles; Thymus Gland; Tumor Necrosis Factor-alpha | 2009 |
Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: involvement of extracellular matrix and cell adhesion.
Topics: Apoptosis; Cell Adhesion; Cell Survival; Cluster Analysis; Coloring Agents; DNA; Extracellular Matrix; Gene Expression; Gene Expression Profiling; Humans; Keratinocytes; Matrix Metalloproteinases; Nanoparticles; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Particle Size; Tetrazolium Salts; Thiazoles; Titanium | 2009 |
Design of improved permeation enhancers for transdermal drug delivery.
Topics: Administration, Cutaneous; Algorithms; Animals; Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Design; Embryo, Mammalian; Fibroblasts; Melatonin; Menthol; Mice; Molecular Structure; Neural Networks, Computer; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Pyrrolidinones; Reproducibility of Results; Skin; Skin Absorption; Swine; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2009 |
RACK-1 overexpression protects against goniothalamin-induced cell death.
Topics: Animals; Apoptosis; Blotting, Western; Cell Death; Cell Line; Cell Survival; Clone Cells; Colony-Forming Units Assay; Coloring Agents; Comet Assay; Culture Media; DNA Damage; Humans; Jurkat Cells; Mice; Neuropeptides; Pyrones; Receptors for Activated C Kinase; Tetrazolium Salts; Thiazoles | 2009 |
Peroxotitanates for biodelivery of metals.
Topics: Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Fibroblasts; Humans; Metals; Metals, Heavy; Mitochondria; Oxides; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Titanium | 2009 |
NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Avoidance Learning; Cell Line, Tumor; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flurbiprofen; Humans; Immunoprecipitation; Lipopolysaccharides; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroblastoma; Neuroprotective Agents; Nitric Oxide Synthase Type II; Peptide Fragments; Prostaglandins; Rats; Rats, Long-Evans; Scopolamine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Overexpression of the nuclear factor-κB subunit c-Rel protects against human islet cell death in vitro.
Topics: Adenoviridae; Animals; Apoptosis Regulatory Proteins; Blotting, Western; Cell Death; Cell Survival; Coloring Agents; Electrophoretic Mobility Shift Assay; Female; Gene Expression; Genetic Vectors; Humans; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Microscopy, Confocal; NF-kappa B; Nuclear Proteins; Perfusion; Protein Subunits; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2009 |
FRET quenching of photosensitizer singlet oxygen generation.
Topics: Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Fluorescence Resonance Energy Transfer; Humans; Lysine; Models, Chemical; Oxygen; Photochemistry; Photosensitizing Agents; Protein Structure, Tertiary; Singlet Oxygen; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways.
Topics: Animals; Apoptosis; Cell Nucleus; Cell Survival; Coloring Agents; Epithelial Cells; Glycogen Synthase Kinase 3; Hydrogen Peroxide; In Situ Nick-End Labeling; Janus Kinase 2; Kidney; Kidney Tubules, Proximal; Mice; Oxidants; Plasmids; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Transglutaminases | 2009 |
Cytotoxic effect of a 35% hydrogen peroxide bleaching gel on odontoblast-like MDPC-23 cells.
Topics: Animals; Cattle; Cell Line; Cell Survival; Cells, Cultured; Coloring Agents; Dental Enamel; Dentin; Diffusion; Gels; Hydrogen Peroxide; Light; Microscopy, Electron, Scanning; Odontoblasts; Oxidants; Random Allocation; Tetrazolium Salts; Thiazoles; Tooth Bleaching | 2009 |
A comparative in vitro evaluation of cytotoxic effects of EDTA and maleic acid: root canal irrigants.
Topics: Aldehyde Reductase; Animals; Cell Count; Cell Death; Cell Line; Cell Survival; Chelating Agents; Clone Cells; Coloring Agents; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Fibroblasts; Maleates; Materials Testing; Root Canal Irrigants; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flame Retardants; Halogenated Diphenyl Ethers; Humans; Lipid Peroxidation; Models, Statistical; Neuroblastoma; Neurons; Oxidative Stress; Polybrominated Biphenyls; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Trypan Blue | 2010 |
Photodynamic properties of ZnTPPS(4), ClAlPcS(2) and ALA in human melanoma G361 cells.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Radiation; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Humans; Indoles; Light; Melanoma, Experimental; Membrane Potentials; Metalloporphyrins; Microscopy, Fluorescence; Mitochondrial Membranes; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Propidium; Reactive Oxygen Species; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2010 |
A cobalt-based tetrazolium salts reduction test to assay polyphenols.
Topics: Antioxidants; Bacteria; Chelating Agents; Cobalt; Flavonoids; Luminescent Measurements; Nitroblue Tetrazolium; Oxidation-Reduction; Phenols; Polyphenols; Tetrazolium Salts; Thiazoles | 2009 |
Endocytic mechanisms and toxicity of a functionalized fullerene in human cells.
Topics: Adenosine Triphosphate; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Drug Delivery Systems; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Fullerenes; Humans; Lysosomes; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Models, Molecular; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Occludin gene expression as an early in vitro sign for mild eye irritation assessment.
Topics: Cell Survival; Coloring Agents; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Eye Diseases; Fluorescent Antibody Technique; Gene Expression; Genetic Markers; Humans; In Vitro Techniques; Interleukin-8; Irritants; Membrane Proteins; Occludin; Ophthalmic Solutions; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2010 |
Comparative antidotal efficacy of benzylpenicillin, ceftazidime and rifamycin in cultured human hepatocytes intoxicated with α-amanitin.
Topics: Alpha-Amanitin; Anti-Bacterial Agents; Antidotes; Ceftazidime; Cell Survival; Cells, Cultured; Hepatocytes; Humans; L-Lactate Dehydrogenase; Mushroom Poisoning; Penicillin G; Rifamycins; Tetrazolium Salts; Thiazoles | 2009 |
Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure.
Topics: Acetylation; Arsenicals; Blotting, Western; Chromatin; Coloring Agents; Dose-Response Relationship, Drug; Epithelial Cells; Gene Silencing; Histone Acetyltransferases; Humans; Mass Spectrometry; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae; Tetrazolium Salts; Thiazoles; Urinary Bladder | 2009 |
Assessment of the optimized SkinEthic Reconstructed Human Epidermis (RHE) 42 bis skin irritation protocol over 39 test substances.
Topics: Animal Testing Alternatives; Cell Survival; Coloring Agents; Epidermis; Humans; Irritants; Quality Control; Reproducibility of Results; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles; Toxicology | 2010 |
A catch-up validation study on reconstructed human epidermis (SkinEthic RHE) for full replacement of the Draize skin irritation test.
Topics: Animal Testing Alternatives; Animals; Cell Survival; Cells, Cultured; Coloring Agents; Epidermis; Humans; Interleukin-1alpha; Irritants; Keratinocytes; Predictive Value of Tests; Rabbits; Reference Standards; Skin Irritancy Tests; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Toxicology | 2010 |
C-terminal mechano growth factor protects dopamine neurons: a novel peptide that induces heme oxygenase-1.
Topics: Animals; Cell Line; DNA Fragmentation; Dopamine; Enzyme Induction; Heme Oxygenase-1; Insulin-Like Growth Factor I; Membrane Potentials; Mitochondrial Membranes; Neostriatum; Neurons; Neuroprotective Agents; Oxidopamine; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; STAT5 Transcription Factor; Substantia Nigra; Sympatholytics; Tetrazolium Salts; Thiazoles; Tumor Suppressor Proteins; Up-Regulation | 2009 |
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Cell Proliferation; Circular Dichroism; Dose-Response Relationship, Drug; Humans; Mice; Microscopy, Electron, Transmission; Molecular Conformation; Molecular Structure; Neuroblastoma; Peptide Fragments; Protein Structure, Quaternary; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Tetrazolium Salts; Thiazoles | 2009 |
Effect of cinnamon oil on icaA expression and biofilm formation by Staphylococcus epidermidis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Microbial Viability; Oils, Volatile; Staphylococcal Infections; Staphylococcus epidermidis; Tetrazolium Salts; Thiazoles | 2009 |
Membrane sterol depletion impairs miltefosine action in wild-type and miltefosine-resistant Leishmania donovani promastigotes.
Topics: Animals; Antiprotozoal Agents; Cell Membrane; Drug Resistance; Leishmania donovani; Lipid Metabolism; Microbial Viability; Mitochondria; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Phosphorylcholine; Sterols; Tetrazolium Salts; Thiazoles | 2009 |
Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells.
Topics: Adenomatous Polyposis Coli Protein; Antineoplastic Agents; beta Catenin; Cadherins; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Line, Tumor; Coloring Agents; Culture Media, Serum-Free; Cyclin D1; Fluorescent Antibody Technique, Direct; Fluorouracil; Heat-Shock Proteins; Humans; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2009 |
Carbon dioxide laser irradiation stimulates mineralization in rat dental pulp cells.
Topics: Animals; Anthraquinones; Ascorbic Acid; Calcification, Physiologic; Cell Survival; Cells, Cultured; Collagen; Collagen Type I; Coloring Agents; Culture Media; Dental Pulp; Female; Glycerophosphates; HSP47 Heat-Shock Proteins; Lasers, Gas; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel.
Topics: Anilides; Animals; Benzamides; Biological Transport; Cell Survival; CHO Cells; Chromans; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Epithelial Sodium Channels; Hypoglycemic Agents; Insulin; Membrane Potentials; Pioglitazone; PPAR gamma; Pyridines; Rosiglitazone; Sodium; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2009 |
Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Drosophila; Glutamine; Humans; Microscopy, Confocal; Microscopy, Electron; Mitochondria; Phenotype; Phosphotransferases; Recombinant Proteins; RNA Interference; Selenium; Tetrazolium Salts; Thiazoles | 2009 |
Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects.
Topics: Annexin A5; Apoptosis; Cell Extracts; Cell Line; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coloring Agents; Enzyme Inhibitors; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Humans; Immunoblotting; Immunomodulation; Intercellular Adhesion Molecule-1; Interferon-gamma; Ligands; Nitriles; Phenols; Propidium; Propionates; Protein Isoforms; Pyrazoles; Salivary Glands, Minor; Tetrazolium Salts; Thiazoles; Vascular Cell Adhesion Molecule-1 | 2009 |
Cytotoxic clerodane diterpenoids from the leaves of Polyalthia longifolia.
Topics: Cell Line, Tumor; Cell Proliferation; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Humans; India; Inhibitory Concentration 50; Molecular Structure; Plant Extracts; Plant Leaves; Polyalthia; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2010 |
Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.
Topics: Acetylation; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylases; HSP70 Heat-Shock Proteins; Immunoglobulins; Neurons; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Valproic Acid | 2009 |
Protection against free radicals (UVB irradiation) of a water-soluble enzymatic extract from rice bran. Study using human keratinocyte monolayer and reconstructed human epidermis.
Topics: Antioxidants; Cell Survival; Coloring Agents; Cosmetics; Epidermal Cells; Epidermis; Free Radical Scavengers; Free Radicals; Humans; Irritants; Keratinocytes; Lipid Peroxidation; Malondialdehyde; Oryza; Peptide Hydrolases; Plant Extracts; Radiation-Protective Agents; Sunscreening Agents; Tetrazolium Salts; Thiazoles; Ultraviolet Rays; Vitamin E | 2010 |
Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity.
Topics: Antineoplastic Agents; Blotting, Western; Cell Nucleus; Chemokine CCL2; Coloring Agents; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Humans; Luciferases; NF-kappa B; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; U937 Cells | 2010 |
Effect of purple sweet potato anthocyanins on beta-amyloid-mediated PC-12 cells death by inhibition of oxidative stress.
Topics: Amyloid beta-Peptides; Animals; Anthocyanins; Antioxidants; Apoptosis; Calcium; Caspase 3; Cell Survival; Coloring Agents; Flow Cytometry; Ipomoea batatas; Lipid Peroxidation; Membrane Potentials; Mitochondria; Mitochondrial Membranes; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line.
Topics: Air Pollutants; Animals; Cell Line; Cell Survival; Chemokines; Coloring Agents; Cytokines; Europe; Inflammation; Macrophages; Mice; Nitric Oxide; Particle Size; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Water | 2009 |
Protective effects of myricetin against ultraviolet-B-induced damage in human keratinocytes.
Topics: Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; DNA; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Lipid Peroxidation; Male; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Sunscreening Agents; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2010 |
In vitro mammalian cytotoxicological study of PAMAM dendrimers - towards quantitative structure activity relationships.
Topics: Biocompatible Materials; Cell Line; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Dendrimers; Electrochemistry; Humans; Indicators and Reagents; Keratinocytes; Neutral Red; Oxazines; Particle Size; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Xanthenes | 2010 |
[MTT assay for detecting osteosarcoma cell apoptosis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Humans; Osteosarcoma; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2009 |
Lactacystin requires reactive oxygen species and Bax redistribution to induce mitochondria-mediated cell death.
Topics: Acetylcysteine; Apoptosis; bcl-2-Associated X Protein; Cell Death; Cell Line, Tumor; Cell Survival; Coloring Agents; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Membrane Potential, Mitochondrial; Mitochondria, Liver; Neuroblastoma; Reactive Oxygen Species; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles | 2009 |
Effects of enamel matrix derivative on proliferation/viability, migration, and expression of angiogenic factor and adhesion molecules in endothelial cells in vitro.
Topics: Angiogenesis Inducing Agents; Angiopoietin-2; Cell Count; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Conditioned; Culture Media, Serum-Free; Dental Enamel Proteins; E-Selectin; Endothelial Cells; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta1; Umbilical Veins | 2009 |
Effect of laser-induced dentin modifications on periodontal fibroblasts and osteoblasts: a new in vitro model.
Topics: Alveolar Process; Animals; Cell Adhesion; Cell Line; Cell Proliferation; Cell Shape; Coloring Agents; Dentin; Fibroblasts; Humans; Lasers, Solid-State; Microscopy, Electron, Scanning; Osteoblasts; Periodontal Ligament; Pseudopodia; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway.
Topics: Animals; Antioxidants; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Hydroquinones; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; NF-E2-Related Factor 2; Quinolinic Acid; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Extract from the leaf of nucifera reduced the development of atherosclerosis via inhibition of vascular smooth muscle cell proliferation and migration.
Topics: Animals; Apoptosis; Arecaceae; Atherosclerosis; bcl-2-Associated X Protein; Blotting, Western; Cell Line; Cell Movement; Cell Proliferation; Coloring Agents; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; In Vitro Techniques; Indoles; Myocytes, Smooth Muscle; Plant Extracts; Plant Leaves; Rabbits; Rats; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53; Wound Healing | 2010 |
Glimepiride induces proliferation and differentiation of rat osteoblasts via the PI3-kinase/Akt pathway.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Blotting, Western; Cell Differentiation; Cell Proliferation; Chromones; Coloring Agents; Enzyme Inhibitors; Hypoglycemic Agents; Morpholines; Oncogene Protein v-akt; Osteoblasts; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Sulfonylurea Compounds; Tetrazolium Salts; Thiazoles | 2010 |
A direct cross-talk between interferon-gamma and sonic hedgehog signaling that leads to the proliferation of neuronal precursor cells.
Topics: Animals; Antimetabolites; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; Coloring Agents; Hedgehog Proteins; Humans; Interferon-gamma; Mice; Mice, Inbred C57BL; Mitosis; Neurons; Nuclease Protection Assays; Receptor Cross-Talk; Ribonucleases; RNA; Signal Transduction; STAT1 Transcription Factor; Tetrazolium Salts; Thiazoles | 2010 |
Radiosensitization effect of STI-571 on pancreatic cancer cells in vitro.
Topics: Analysis of Variance; Apoptosis; Benzamides; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Formazans; Genes, ras; Humans; Imatinib Mesylate; Mutation; Pancreatic Neoplasms; Phospholipase C gamma; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Pyrimidines; Radiation Tolerance; Radiation-Sensitizing Agents; Receptor, Platelet-Derived Growth Factor beta; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8-(4-chlorophenylthio)-modified cAMP analogs and their hydrolytic products.
Topics: Amino Acid Motifs; Animals; Apoptosis; Cell Line; Coloring Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Equilibrative Nucleoside Transporter 1; Humans; Hydrolysis; PC12 Cells; Phosphorylation; Rats; Receptor, Adenosine A2A; Tetrazolium Salts; Thiazoles | 2009 |
Fibril fragmentation enhances amyloid cytotoxicity.
Topics: Amyloid; Amyloidosis; Animals; Benzothiazoles; Cell Survival; Chickens; HeLa Cells; Humans; Kinetics; Liposomes; Mice; Microscopy, Atomic Force; Models, Biological; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2009 |
Relationship of mRNA expressions of RanBP2 and topoisomerase II isoforms to cytotoxicity of amrubicin in human lung cancer cell lines.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Biomarkers; Blotting, Western; Cell Line, Tumor; Cell Survival; Chromosomal Instability; Coloring Agents; DNA Topoisomerases, Type II; Humans; Isoenzymes; Lung Neoplasms; Molecular Chaperones; Nuclear Pore Complex Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2010 |
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carotenoids; Catalase; Coloring Agents; Electron Transport Complex IV; Huntington Disease; Lipid Peroxidation; Lycopene; Male; Motor Activity; NADH Dehydrogenase; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide; Nitrites; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Signal Transduction; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2009 |
Reciprocal effects of conditioned medium on cultured glioma cells and neural stem cells.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Corpus Striatum; Culture Media, Conditioned; Embryo, Mammalian; Glioma; Hippocampus; Humans; Mice; Nerve Tissue Proteins; Neurons; Stem Cells; Tetrazolium Salts; Thiazoles | 2009 |
Endodontic antimicrobial photodynamic therapy: safety assessment in mammalian cell cultures.
Topics: Apoptosis; Blotting, Western; Cell Line; Cell Survival; Coloring Agents; Dental Pulp Cavity; Disinfection; Fibroblasts; Gingiva; Humans; Lasers, Semiconductor; Materials Testing; Methylene Blue; Mitochondria; Neutral Red; Osteoblasts; Photochemotherapy; Photosensitizing Agents; Root Canal Therapy; Safety; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Evaluation of the effects of endodontic materials on fibroblast viability and cytokine production.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Calcium Hydroxide; Cell Line; Cell Survival; Coloring Agents; Drug Combinations; Fibroblasts; Interleukin-1beta; Interleukin-6; Interleukins; Materials Testing; Mice; Oxides; Root Canal Filling Materials; Salicylates; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10).
Topics: Antineoplastic Agents; Benzamides; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Models, Chemical; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Piperazines; Pyrimidines; Tetrazolium Salts; Thiazoles | 2009 |
Ibuprofen upregulates expressions of matrix metalloproteinase-1, -8, -9, and -13 without affecting expressions of types I and III collagen in tendon cells.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Count; Cell Survival; Cells, Cultured; Collagen Type I; Collagen Type III; Coloring Agents; Electrophoresis, Gel, Two-Dimensional; Gene Expression; Ibuprofen; Immunoenzyme Techniques; Matrix Metalloproteinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Diallyl sulfide inhibits murine WEHI-3 leukemia cells in BALB/c mice in vitro and in vivo.
Topics: Allyl Compounds; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Indicators and Reagents; Leukemia; Liver; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Spleen; Sulfides; Tetrazolium Salts; Thiazoles | 2009 |
D-beta-hydroxybutyrate prevents MPP+-induced neurotoxicity in PC12 cells.
Topics: 3-Hydroxybutyric Acid; Acridine Orange; Animals; Apoptosis; Cell Survival; Coloring Agents; Dopamine beta-Hydroxylase; Flow Cytometry; Fluorescent Dyes; Glutathione; Lipid Peroxidation; Malondialdehyde; MPTP Poisoning; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Protective effects of acetyl-L-carnitine on cisplatin cytotoxicity and oxidative stress in neuroblastoma.
Topics: Acetylcarnitine; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cisplatin; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Glutathione; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Neuroblastoma; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Proto-Oncogene Proteins c-myc; Tetrazolium Salts; Thiazoles | 2010 |
Cytotoxicity and degree of conversion of orthodontic adhesives.
Topics: Acetone; Acrylic Resins; Aluminum Silicates; Animals; Cell Survival; Chlorocebus aethiops; Coloring Agents; Glass Ionomer Cements; Materials Testing; Orthodontic Appliances; Oxygen; Polymers; Resin Cements; Solvents; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors; Vero Cells | 2009 |
A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI.
Topics: Adenoviridae; Animals; Anti-Bacterial Agents; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Comet Assay; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Breaks, Double-Stranded; DNA Damage; Dose-Response Relationship, Drug; Doxycycline; Embryo, Mammalian; Enzyme Activation; Fibroblasts; Fluorescent Antibody Technique, Direct; Genetic Vectors; Immunohistochemistry; Mice; Mice, Inbred C57BL; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Transgenes | 2009 |
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells.
Topics: Animals; Animals, Newborn; Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Enzyme Inhibitors; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Green Fluorescent Proteins; Humans; Mutation; Nerve Tissue Proteins; Neurons; Oxidative Stress; Quinazolines; Signal Transduction; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrphostins | 2010 |
Alpha-lipoic acid prevents bupivacaine-induced neuron injury in vitro through a PI3K/Akt-dependent mechanism.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Annexin A5; Apoptosis; Bupivacaine; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Neuroblastoma; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thioctic Acid; Time Factors; Vitamin B Complex | 2010 |
Allium sativum L. extract prevents methyl mercury-induced cytotoxicity in peripheral blood leukocytes (LS).
Topics: Acetylglucosamine; Adenosine Deaminase; Allium; Antioxidants; Cell Survival; Coloring Agents; Humans; Immunity, Cellular; In Vitro Techniques; Leukocytes; Methylmercury Compounds; Oxazines; Plant Extracts; Tetrazolium Salts; Thiazoles; Xanthenes | 2010 |
Inhibition of prostate cancer by suicide gene targeting the FCY1 and HSV-TK genes.
Topics: Cell Line, Tumor; Female; Genes, Transgenic, Suicide; Genetic Therapy; HeLa Cells; Humans; Male; Models, Genetic; Neoplasm Metastasis; Promoter Regions, Genetic; Prostatic Neoplasms; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Treatment Outcome | 2009 |
Down-regulation of Egr-1 by siRNA inhibits growth of human prostate carcinoma cell line PC-3.
Topics: Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Early Growth Response Protein 1; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2009 |
CD4+ T cell-derived IL-2 signals during early priming advances primary CD8+ T cell responses.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Colorimetry; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Models, Biological; S Phase; Signal Transduction; Spleen; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Up-regulation of the type 3 ryanodine receptor is neuroprotective in the TgCRND8 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; Mutation; Neurons; Peptide Fragments; Phosphopyruvate Hydratase; Potassium; Presenilin-1; RNA, Messenger; RNA, Small Interfering; Ryanodine Receptor Calcium Release Channel; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Improved biological performance of microarc-oxidized low-modulus Ti-24Nb-4Zr-7.9Sn alloy.
Topics: Alkaline Phosphatase; Alloys; Animals; Biocompatible Materials; Bone Development; Cell Survival; Coloring Agents; Male; Materials Testing; Mice; Microscopy, Electron, Scanning; Osteoblasts; Oxidation-Reduction; Rabbits; Rats; Stress, Mechanical; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles | 2010 |
Stable knockdown of heparanase expression in gastric cancer cells in vitro.
Topics: Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronidase; Humans; In Vitro Techniques; Neoplasm Invasiveness; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2009 |
Hypoxia protects neuronal cells from human prion protein fragment-induced apoptosis.
Topics: Analysis of Variance; Apoptosis; Caspase 3; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial; Neuroblastoma; Oncogene Protein v-akt; Peptide Fragments; Prions; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2010 |
Dynamic cytotoxic response to microcystins using microelectronic sensor arrays.
Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Humans; Mice; Microcystins; Microelectrodes; Organic Anion Transporters, Sodium-Independent; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2009 |
JNK/ATF2 pathway is involved in iodinated contrast media-induced apoptosis.
Topics: Activating Transcription Factor 2; Animals; Apoptosis; Cell Survival; Contrast Media; Diatrizoate; Humans; In Situ Nick-End Labeling; Iodine; Kidney; MAP Kinase Kinase 4; Models, Biological; Phosphorylation; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2010 |
Optimization of a new non-viral vector for transfection: Eudragit nanoparticles for the delivery of a DNA plasmid.
Topics: Adsorption; Cell Line, Tumor; DNA; Drug Delivery Systems; Genetic Vectors; Humans; Lipids; Methacrylates; Mitochondria; Nanoparticles; Nanotechnology; Neoplasms; Plasmids; Polymers; Polymethacrylic Acids; Recombination, Genetic; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
In vitro biological response to a self-adhesive resin cement under different curing strategies.
Topics: Animals; Cell Survival; Culture Media; Light; Lipopolysaccharides; Macrophages, Alveolar; Nitric Oxide; Rats; Resin Cements; Tetrazolium Salts; Thiazoles; Tissue Adhesives | 2010 |
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity.
Topics: Adenosine Triphosphate; Cell Survival; DNA, Mitochondrial; Fibroblasts; Haplotypes; Hexanones; Humans; Mitochondria; Models, Genetic; Mutation; Optic Atrophy, Hereditary, Leber; Polymerase Chain Reaction; Sequence Analysis, DNA; Tetrazolium Salts; Thiazoles; Toluene | 2009 |
Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7, 22-diene-3 beta, 5 alpha, 6 beta-triol, with new activities from the marine-derived fungus Trichoderma sp.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; China; Cyclopentanes; Drug Evaluation, Preclinical; Geologic Sediments; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Tetrazolium Salts; Thiazoles; Trichoderma | 2010 |
Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway.
Topics: Cell Line, Tumor; Cell Proliferation; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2009 |
Actions of redox-active compound resveratrol under hydrogen peroxide insult in C6 astroglial cells.
Topics: Animals; Antioxidants; Ascorbic Acid; Astrocytes; Cell Line; Cell Survival; Coloring Agents; DNA Damage; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Lipids; Micronucleus Tests; Oxidants; Oxidation-Reduction; Rats; Resveratrol; Stilbenes; Tars; Tetrazolium Salts; Thiazoles | 2010 |
Inhibitory effects of pharmacological doses of dexamethasone on mineralization of mesenchymal progenitor cells in vitro.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Calcification, Physiologic; Cell Line; Cell Proliferation; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Insulin-Like Growth Factor I; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Sp7 Transcription Factor; Tetrazolium Salts; Thiazoles; Transcription Factors | 2009 |
High-level expression and purification of heparin-binding epidermal growth factor (HB-EGF) with SUMO fusion.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cloning, Molecular; Coloring Agents; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression; Genetic Vectors; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mitosis; Molecular Sequence Data; Plasmids; Protein Binding; Recombinant Fusion Proteins; Small Ubiquitin-Related Modifier Proteins; Solubility; Tetrazolium Salts; Thiazoles | 2010 |
Investigation of the immunosuppressive activity of Physalin H on T lymphocytes.
Topics: Animals; Blotting, Western; Cell Proliferation; Coloring Agents; Concanavalin A; Dinitrofluorobenzene; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heme Oxygenase-1; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppressive Agents; Indicators and Reagents; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Ovalbumin; Reverse Transcriptase Polymerase Chain Reaction; Secosteroids; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2010 |
Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.
Topics: Animals; Bacterial Proteins; Bronchoalveolar Lavage Fluid; Humans; Inflammation; Kidney; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Streptococcus pneumoniae; Streptolysins; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 2; Toll-Like Receptor 4; Virulence Factors | 2009 |
Na+/H+ exchanger blockade inhibits the expression of vascular endothelial growth factor in SGC7901 cells.
Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; K562 Cells; Neovascularization, Pathologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Hydrogen Exchangers; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor A | 2010 |
Enhanced tumor radiosensitivity by a survivin dominant-negative mutant.
Topics: Animals; Apoptosis; Carcinoma, Lewis Lung; Cholesterol; Combined Modality Therapy; Fatty Acids, Monounsaturated; Genes, Dominant; Inhibitor of Apoptosis Proteins; Liposomes; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Plasmids; Platelet Endothelial Cell Adhesion Molecule-1; Quaternary Ammonium Compounds; Radiation Tolerance; Radiotherapy; Repressor Proteins; Survivin; Tetrazolium Salts; Thiazoles | 2010 |
Imatinib mesylate (STI571) enhances amrubicin-induced cytotoxic activity through inhibition of the phosphatidylinositol 3-kinase/Akt pathway in small cell lung cancer cells.
Topics: Anthracyclines; Benzamides; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Imatinib Mesylate; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Piperazines; Proto-Oncogene Proteins c-akt; Pyrimidines; Small Cell Lung Carcinoma; Tetrazolium Salts; Thiazoles | 2010 |
Synthesis and bioimmunological efficiency of poly(2-oxazolines) containing a free amino group.
Topics: Animals; Biocompatible Materials; Cell Survival; Macrophages; Materials Testing; Mice; Oxazoles; Phagocytosis; Polymers; Polysaccharides; Proteins; Respiratory Burst; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Novel ceramic bone replacement material CeraBall seeded with human mesenchymal stem cells.
Topics: Biocompatible Materials; Bone Substitutes; Calcium Phosphates; Cell Adhesion; Cell Proliferation; Cell Shape; Cells, Cultured; Coloring Agents; Compressive Strength; Dental Stress Analysis; Humans; Materials Testing; Mesenchymal Stem Cells; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2010 |
An in vitro drug-induced hepatotoxicity screening system using CYP3A4-expressing and gamma-glutamylcysteine synthetase knockdown cells.
Topics: Adenoviridae; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Coloring Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Gentian Violet; Glutamate-Cysteine Ligase; Glutathione; Hepatocytes; Kinetics; Microsomes, Liver; Nucleic Acid Conformation; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
[Expression and biological roles of heat shock protein 25 in rat dental follicle cells].
Topics: Alkaline Phosphatase; Animals; Cell Proliferation; Cells, Cultured; Dental Sac; Flow Cytometry; Fluorescent Antibody Technique, Indirect; HSP27 Heat-Shock Proteins; Immunohistochemistry; Rats; Tetrazolium Salts; Thiazoles; Up-Regulation | 2009 |
Antimicrobial compounds from the endophytic fungus Fusarium sp. Ppf4 isolated from the medicinal plant Paris polyphylla var. yunnanensis.
Topics: Anti-Bacterial Agents; Bacteria; Chromatography, Thin Layer; Colorimetry; Coloring Agents; Fusarium; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Roots; Plants, Medicinal; Spores, Bacterial; Steroids; Tetrazolium Salts; Thiazoles | 2009 |
Secondary metabolites from the mangrove endophytic fungus Penicillium sp. (SBE-8).
Topics: Antibiotics, Antineoplastic; Coloring Agents; Fermentation; Heterocyclic Compounds, 3-Ring; Humans; KB Cells; Magnetic Resonance Spectroscopy; Penicillium; Rhizophoraceae; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Cytotoxic activity of seco-entkaurenes from Croton caracasana on human cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Coloring Agents; Croton; Diterpenes; Drug Screening Assays, Antitumor; Flowers; Humans; Tetrazolium Salts; Thiazoles | 2009 |
Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.
Topics: Adult; Apoptosis; Benzazepines; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Division; Cell Proliferation; Cells, Cultured; Coloring Agents; Cyclin B1; Endometrium; Female; Flow Cytometry; G2 Phase; Humans; In Vitro Techniques; Indoles; Progesterone; Tetrazolium Salts; Thiazoles | 2009 |
Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biotransformation; Blotting, Western; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Coloring Agents; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Humans; Melanoma, Experimental; NF-kappa B; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Plant Extracts; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Signal Transduction; Tetrazolium Salts; Thiazoles; Ubiquitin | 2010 |
Oleanolic acid and ursolic acid induce apoptosis in four human liver cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Adhesion; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA Fragmentation; Humans; Intercellular Adhesion Molecule-1; Liver Neoplasms; Membrane Potentials; Mitochondrial Membranes; Neoplasm Metastasis; Oleanolic Acid; Sodium-Potassium-Exchanging ATPase; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid; Vascular Endothelial Growth Factor A | 2010 |
Evaluation of WLBU2 peptide and 3-O-octyl-sn-glycerol lipid as active ingredients for a topical microbicide formulation targeting Chlamydia trachomatis.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antimicrobial Cationic Peptides; Cell Line; Chlamydia trachomatis; Drug Synergism; Female; Glyceryl Ethers; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Male; Mice; Microbial Sensitivity Tests; Penicillin G; Polymyxin B; Tetrazolium Salts; Thiazoles | 2010 |
Effect of bacterial wax esters in sensitized (A) and non-sensitized (NA) human blood cell incubates.
Topics: Adult; Bacteria; Blood Cells; Cell Proliferation; Coloring Agents; Desensitization, Immunologic; Esters; Female; Gram-Negative Bacteria; Histamine Release; Humans; Hypersensitivity; In Vitro Techniques; Interferon-gamma; Interleukin-4; Lymphocyte Activation; Tetrazolium Salts; Thiazoles; Waxes; Young Adult | 2010 |
Assessment of buffalo semen with the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide reduction assay.
Topics: Animals; Buffaloes; Coloring Agents; Male; Semen; Semen Analysis; Spermatozoa; Tetrazolium Salts; Thiazoles | 2010 |
The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Dacarbazine; DNA Mutational Analysis; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Genes, p53; Humans; Melanoma; O(6)-Methylguanine-DNA Methyltransferase; Pyrazoles; Quinazolines; Temozolomide; Tetrazolium Salts; Thiazoles | 2010 |
Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 2; Caspase Inhibitors; Comet Assay; Cytochromes c; DNA Damage; DNA Topoisomerases, Type II; Enzyme Inhibitors; Flow Cytometry; Glutathione; Goniothalamus; Humans; Jurkat Cells; Oligopeptides; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Pyrones; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Biodistribution of humanized anti-VEGF monoclonal antibody/bevacizumab on peritoneal metastatic models with subcutaneous xenograft of gastric cancer in mice.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Bevacizumab; Blotting, Western; Cell Line, Tumor; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Female; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Paclitaxel; Peritoneal Neoplasms; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tissue Distribution; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Inhibitory effect of Angelicae Tenuissimae Radix on expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells.
Topics: Angelica; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Drugs, Chinese Herbal; Immunoassay; Intramolecular Oxidoreductases; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Nitric Oxide Synthase Type II; Prostaglandin-E Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2010 |
Protective effect of quercetin on the reproductive toxicity of 4-nitrophenol in diesel exhaust particles on male embryonic chickens.
Topics: Animal Feed; Animals; Antioxidants; Cell Count; Cells, Cultured; Chick Embryo; Chickens; Drug Interactions; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Nitrophenols; Oxidative Stress; Quercetin; Reproduction; Spermatogonia; Superoxide Dismutase; Testis; Tetrazolium Salts; Thiazoles; Vehicle Emissions | 2010 |
Bing De Ling, a Chinese herbal formula, inhibits cancer cells growth via p53.
Topics: Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Luciferases; Nuclear Proteins; Proto-Oncogene Proteins; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2010 |
Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro: a preliminary study.
Topics: Adult Stem Cells; Aphanizomenon; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Complex Mixtures; Humans; In Vitro Techniques; Tetrazolium Salts; Thiazoles | 2010 |
Synergistic action of doxorubicin and sulindac in human cervix carcinoma cells - studies on possible mechanisms.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclooxygenase Inhibitors; DNA Primers; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; In Situ Nick-End Labeling; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulindac; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2010 |
Cytocompatibility of regenerated silk fibroin film: a medical biomaterial applicable to wound healing.
Topics: Animals; Biocompatible Materials; Bombyx; Cell Adhesion; Cell Line; Enzyme-Linked Immunosorbent Assay; Fibroins; Flow Cytometry; Humans; Mice; Models, Biological; Silk; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A; Wound Healing | 2010 |
Neuroprotection by baicalein in ischemic brain injury involves PTEN/AKT pathway.
Topics: Analysis of Variance; Animals; Animals, Newborn; Annexin A5; Brain Infarction; Caspase 3; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Flavanones; Glucose; Hypoxia; Immunoprecipitation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Male; Neurologic Examination; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Chitosan-mediated siRNA delivery in vitro: effect of polymer molecular weight, concentration and salt forms.
Topics: Animals; Cell Survival; Chitosan; Cricetinae; Electrophoresis, Agar Gel; Gene Silencing; Genetic Vectors; Glutamates; Green Fluorescent Proteins; HeLa Cells; Humans; Molecular Weight; Particle Size; Polymers; RNA, Small Interfering; Salts; Sodium Chloride; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
Purification, characterization and immunostimulating activity of water-soluble polysaccharide isolated from Capsosiphon fulvescens.
Topics: Adjuvants, Immunologic; Animals; Chlorophyta; Coloring Agents; Cyclooxygenase 2; Cytokines; Dose-Response Relationship, Drug; Interleukin-6; Korea; Macrophages; Mice; Molecular Weight; Monosaccharides; Nitric Oxide Synthase Type II; Polysaccharides; Reverse Transcriptase Polymerase Chain Reaction; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2010 |
In vitro biocompatibility of chitosan porous skin regenerating templates (PSRTs) using primary human skin keratinocytes.
Topics: Biocompatible Materials; Cell Survival; Cells, Cultured; Chitosan; Coloring Agents; Comet Assay; Humans; Interleukin-8; Keratinocytes; Materials Testing; Mutagenicity Tests; Mutagens; Porosity; Regeneration; Skin, Artificial; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2010 |
Development of an in vitro model for radiation-induced effects on oral keratinocytes.
Topics: Biocompatible Materials; Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Proliferation; Cell Shape; Cell Survival; Collagen; Coloring Agents; Dose-Response Relationship, Radiation; Female; Humans; Inflammation Mediators; Interleukin-1alpha; Interleukin-8; Keratinocytes; Ki-67 Antigen; Male; Mouth Mucosa; Radiation Dosage; Stomatitis; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2010 |
Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (-)-gossypol.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Contraceptive Agents, Male; Gossypol; Humans; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Microvilli; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2010 |
Storage correction in cells of patients suffering from mucopolysaccharidoses types IIIA and VII after treatment with genistein and other isoflavones.
Topics: Bone Marrow Transplantation; Chondroitin Sulfates; Dose-Response Relationship, Drug; Fibroblasts; Genistein; Glycosaminoglycans; Humans; Isoflavones; Lysosomes; Models, Biological; Models, Chemical; Mucopolysaccharidosis III; Mucopolysaccharidosis VII; Tetrazolium Salts; Thiazoles | 2010 |
The pyruvic acid analog 3-bromopyruvate interferes with the tetrazolium reagent MTS in the evaluation of cytotoxicity.
Topics: Adenosine Triphosphate; Animals; Annexin A5; Biological Assay; Cell Line; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Pyruvates; Rabbits; Tetrazolium Salts; Thiazoles | 2010 |
Metabotropic glutamate receptor 3 activation prevents nitric oxide-induced death in cultured rat astrocytes.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Animals; Animals, Newborn; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gene Expression Regulation; In Situ Nick-End Labeling; Interferon-gamma; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Donors; Phosphatidylserines; Phosphodiesterase Inhibitors; Polyamines; Polysaccharides; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tetrazolium Salts; Thiazoles | 2010 |
A porous scaffold for bone tissue engineering/45S5 Bioglass derived porous scaffolds for co-culturing osteoblasts and endothelial cells.
Topics: Biocompatible Materials; Bone Substitutes; Ceramics; Coculture Techniques; Coloring Agents; Endothelial Cells; Glass; Humans; Hydrogen-Ion Concentration; Osteoblasts; Oxazines; Porosity; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering; Xanthenes | 2010 |
Antitumor activity and pharmacokinetics of oral gimatecan on pediatric cancer xenografts.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cell Line, Tumor; Cell Proliferation; Child; Chromatography, High Pressure Liquid; Half-Life; Humans; Irinotecan; Male; Mice; Mice, Nude; Neuroblastoma; Rhabdomyosarcoma; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2010 |
Antiviral activities of diarylheptanoids against influenza virus in vitro.
Topics: Alpinia; Antiviral Agents; Diarylheptanoids; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Inhibitory Concentration 50; Microbial Sensitivity Tests; Tetrazolium Salts; Thiazoles | 2010 |
The protective effect of trihexyphenidyl on the beta-amyloid peptide (25-35)-induced cytotoxicity in PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Antimetabolites; Calcium; Cell Survival; Cytosol; Glutathione Peroxidase; Malondialdehyde; Membrane Potential, Mitochondrial; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Trihexyphenidyl | 2010 |
Antimetastatic effects of Terminalia catappa L. on oral cancer via a down-regulation of metastasis-associated proteases.
Topics: Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Peptide Hydrolases; Plant Extracts; Terminalia; Tetrazolium Salts; Thiazoles; Tongue Neoplasms | 2010 |
MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; ErbB Receptors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Inhibitory Concentration 50; MicroRNAs; Models, Biological; Paclitaxel; Phosphorylation; PTEN Phosphohydrolase; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles | 2010 |
The radiation response of androgen-refractory prostate cancer cell line C4-2 derived from androgen-sensitive cell line LNCaP.
Topics: Adenocarcinoma; Androgens; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Repair; DNA, Neoplasm; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, cdc; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Radiation Tolerance; Tetrazolium Salts; Thiazoles | 2010 |
Rosmarinus officinalis extract inhibits human melanoma cell growth.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Coloring Agents; Comet Assay; DNA Damage; Humans; L-Lactate Dehydrogenase; Melanoma; Methanol; Plant Extracts; Rosmarinus; Solvents; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2009 |
Cancer chemopreventive and anticancer evaluation of extracts and fractions from marine macro- and microorganisms collected from Twilight Zone waters around Guam.
Topics: Animals; Anthozoa; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Aromatase Inhibitors; Bacteria; Biphenyl Compounds; Chromatography, High Pressure Liquid; Coloring Agents; Drug Screening Assays, Antitumor; Guam; Marine Biology; NAD(P)H Dehydrogenase (Quinone); NF-kappa B; Picrates; Porifera; Retinoid X Receptors; Seawater; Tetrazolium Salts; Thiazoles; Water Microbiology | 2009 |
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Humans; Neoplasms; Nucleic Acid Synthesis Inhibitors; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2010 |
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway.
Topics: Adenosine Diphosphate Ribose; Animals; Anthraquinones; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Breast Neoplasms; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Female; Humans; In Situ Nick-End Labeling; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Nude; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles | 2010 |
Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; DNA Fragmentation; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Oxidants; Oxidative Stress; Propidium; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
A new C29-sterol with a cyclopropane ring at C-25 and 26 from the Vietnamese marine sponge lanthella sp.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chromatography, Ion Exchange; Chromatography, Thin Layer; Coloring Agents; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Conformation; Porifera; Spectrophotometry, Infrared; Sterols; Tetrazolium Salts; Thiazoles; Vietnam | 2009 |
Grb2-mediated alteration in the trafficking of AbetaPP: insights from Grb2-AICD interaction.
Topics: Amyloid beta-Protein Precursor; Cell Line, Tumor; Centrosome; Exosomes; Gene Expression Regulation; GRB2 Adaptor Protein; Humans; Immunoprecipitation; Luminescent Proteins; Lysosomal-Associated Membrane Protein 2; Neuroblastoma; Protein Interaction Domains and Motifs; Protein Transport; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; rab7 GTP-Binding Proteins; RNA Interference; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2010 |
AMPA receptors serum-dependently mediate GABAA receptor alpha1 and alpha6 subunit down-regulation in cultured mouse cerebellar granule cells.
Topics: Alanine; Animals; Cells, Cultured; Cerebellum; Coloring Agents; Culture Media, Serum-Free; Down-Regulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GluK2 Kainate Receptor; Kainic Acid; Mice; Neurons; Protein Binding; Pyrimidinones; Quinoxalines; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2010 |
Protein adsorption and cell adhesion on polyurethane/Pluronic surface with lotus leaf-like topography.
Topics: Adsorption; Animals; Cattle; Cell Survival; Culture Techniques; Drug Design; Fibrinogen; Mice; Microscopy, Electron, Scanning; Poloxamer; Polyurethanes; Proteins; Serum Albumin; Surface Properties; Tetrazolium Salts; Thiazoles | 2010 |
Choukroun's platelet-rich fibrin (PRF) stimulates in vitro proliferation and differentiation of human oral bone mesenchymal stem cell in a dose-dependent way.
Topics: Alkaline Phosphatase; Biocompatible Materials; Blood Platelets; Calcification, Physiologic; Cell Count; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniques; Coloring Agents; Cytotoxicity Tests, Immunologic; Dose-Response Relationship, Drug; Fibrin; Humans; Leukocytes; Male; Maxilla; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Middle Aged; Osteoblasts; Osteotomy; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors; Tissue and Organ Harvesting; Trypan Blue | 2010 |
Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice.
Topics: Animals; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coculture Techniques; Gene Expression Regulation, Neoplastic; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Neoplasms; Receptor, Angiotensin, Type 2; Signal Transduction; Tetrazolium Salts; Thiazoles; von Willebrand Factor | 2010 |
The anti-cancer peptide, PNC-27, induces tumor cell lysis as the intact peptide.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Coloring Agents; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Green Fluorescent Proteins; Humans; L-Lactate Dehydrogenase; Microscopy, Confocal; Necrosis; Neoplasms; Rhodamines; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2010 |
One new guaiane-type sesquiterpene glycoside from the fruits of Daucus carota L.
Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Coloring Agents; Daucus carota; Drug Screening Assays, Antitumor; Fruit; Glucosides; Glycosides; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Sesquiterpenes, Guaiane; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2010 |
Anticancer drugs exert differential apoptotic and cytotoxic effects on glioblastoma primary cultures with various EGFR and bcl-2 profiles.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coloring Agents; ErbB Receptors; Flow Cytometry; Genes, bcl-2; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Immunohistochemistry; Middle Aged; Tetrazolium Salts; Thiazoles | 2009 |
Evaluation of the MTT lymphocyte proliferation assay for the diagnosis of neurocysticercosis.
Topics: Animals; Cell Proliferation; Female; Humans; Immunoassay; Lymphocytes; Male; Neurocysticercosis; Sensitivity and Specificity; Taenia solium; Tetrazolium Salts; Thiazoles | 2010 |
Reversal of mdr1-mediated multidrug resistance in human leukemia cells by a new spin-labeled derivative of podophyllotoxin.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Cell Line, Tumor; DNA Fragmentation; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; G2 Phase; Humans; K562 Cells; Leukemia; Podophyllotoxin; Spin Labels; Tetrazolium Salts; Thiazoles | 2010 |
Chemical composition of the essential oils of two Citrus species and their biological activities.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Chromatography, Gas; Citrus; Coloring Agents; Distillation; Ethers; Fruit; Hexanes; Humans; Lipoxygenase Inhibitors; Mass Spectrometry; Oils, Volatile; Tetrazolium Salts; Thiazoles; Trypanocidal Agents; Trypanosoma brucei brucei | 2010 |
Assessing cytotoxicity of boron nitride nanotubes: Interference with the MTT assay.
Topics: Boron Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Humans; Nanotubes; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2010 |
Design, synthesis and antimalarial/anticancer evaluation of spermidine linked artemisinin conjugates designed to exploit polyamine transporters in Plasmodium falciparum and HL-60 cancer cell lines.
Topics: Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Artemisinins; Biogenic Polyamines; Carrier Proteins; Coloring Agents; Drug Design; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Plasmodium falciparum; Spermidine; Tetrazolium Salts; Thiazoles | 2010 |
An evaluation of a cultured human corneal epithelial tissue model for the determination of the ocular irritation potential of pharmaceutical process materials.
Topics: Animal Testing Alternatives; Cell Survival; Cells, Cultured; Drug-Related Side Effects and Adverse Reactions; Epithelium, Corneal; Humans; Irritants; Necrosis; Pharmaceutical Preparations; Tetrazolium Salts; Thiazoles; Xenobiotics | 2010 |
Decontamination of tetramethylammonium hydroxide (TMAH) splashes: promising results with Diphoterine in vitro.
Topics: Burns, Chemical; Cell Line; Cell Survival; Coloring Agents; Epidermis; Humans; Occupational Exposure; Ophthalmic Solutions; Organic Chemicals; Quaternary Ammonium Compounds; Skin; Skin Diseases; Tetrazolium Salts; Therapeutic Irrigation; Thiazoles; Water | 2010 |
The novel multifunctional, iron-chelating drugs M30 and HLA20 protect pancreatic beta-cell lines from oxidative stress damage.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Catalase; Cell Line; Cell Survival; Coloring Agents; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hydrogen Peroxide; Hydroxyquinolines; Insulin-Secreting Cells; Iron Chelating Agents; Membrane Potentials; Mitochondria; Monoamine Oxidase Inhibitors; Oxidants; Oxidative Stress; Piperazines; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Transdentinal protective role of sodium ascorbate against the cytopathic effects of H2O2 released from bleaching agents.
Topics: Antioxidants; Ascorbic Acid; Carbamide Peroxide; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Survival; Coloring Agents; Dentin; Dentin Permeability; Diffusion; Humans; Hydrogen Peroxide; Materials Testing; Microscopy, Electron, Scanning; Odontoblasts; Oxidants; Peroxides; Protective Agents; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Bleaching; Urea | 2010 |
Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Lipids; Naphthalenes; Naphthoquinones; Solubility; Styrenes; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2010 |
Despite its role in assembly, methionine 35 is not necessary for amyloid beta-protein toxicity.
Topics: Amino Acid Substitution; Amyloid beta-Peptides; Animals; Cells, Cultured; Circular Dichroism; Coloring Agents; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Light; Methionine; Microscopy, Electron, Transmission; Neurons; Peptides; Protein Conformation; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2010 |
Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Calpain; Coloring Agents; Cyclin-Dependent Kinase 5; Glutamic Acid; Humans; Immunohistochemistry; MAP Kinase Kinase 6; Mice; Mice, Transgenic; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Unmethylated CpG oligodeoxynucleotides activate head kidney leukocytes of Atlantic cod, Gadus morhua.
Topics: Acid Phosphatase; Aeromonas salmonicida; Analysis of Variance; Animals; Gadus morhua; In Vitro Techniques; Kidney; Leukocytes; Oligodeoxyribonucleotides; Peroxidase; Respiratory Burst; Tetrazolium Salts; Thiazoles; Vibrio | 2010 |
Vanadate affects proliferation of healing fibroblasts, cellular production of collagen, and expression of alpha-SMA in vitro.
Topics: Actins; Animals; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression Regulation; In Vitro Techniques; Ligaments; Male; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Vanadates | 2010 |
Abeta20-29 peptide blocking apoE/Abeta interaction reduces full-length Abeta42/40 fibril formation and cytotoxicity in vitro.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Benzothiazoles; Cell Survival; Cells, Cultured; Fluorescent Dyes; Humans; Microscopy, Electron; Neurofibrils; Peptide Fragments; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2010 |
Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Calcineurin inhibitor tacrolimus does not interfere with the suppression of hepatitis C virus infection by interferon-alpha.
Topics: Antiviral Agents; Calcineurin Inhibitors; Cell Proliferation; Cell Survival; Gene Expression Regulation; Hepacivirus; Hepatitis C; Humans; Immunosuppressive Agents; Interferon-alpha; T-Lymphocytes; Tacrolimus; Tetrazolium Salts; Thiazoles | 2010 |
Evaluation of cytotoxicity of two root canal filling materials by MTT assay.
Topics: Animals; Dimethylpolysiloxanes; Drug Combinations; Fibroblasts; Gutta-Percha; L Cells; Materials Testing; Mice; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Bortezomib induces apoptosis in human neuroblastoma CHP126 cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boronic Acids; Bortezomib; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression; Humans; Indicators and Reagents; Neuroblastoma; NF-kappa B; Oncogene Protein p21(ras); Poly(ADP-ribose) Polymerases; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Endotoxin promotes adverse effects of amorphous silica nanoparticles on lung epithelial cells in vitro.
Topics: Cell Line; Cell Membrane; Cell Survival; DNA Damage; Drug Combinations; Drug Therapy, Combination; Glutathione; Humans; Lipopolysaccharides; Lung; Nanoparticles; Nitrates; Nitrites; Oxidative Stress; Reactive Oxygen Species; Respiratory Mucosa; Silicon Dioxide; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2010 |
Antioxidant and cytotoxic effect of oxidized lutein in human cervical carcinoma cells (HeLa).
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Cell Proliferation; Chromatography, High Pressure Liquid; Coloring Agents; Glutathione; HeLa Cells; Humans; Lutein; Malondialdehyde; Mass Spectrometry; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2010 |
The modified high-density survival assay is the useful tool to predict the effectiveness of fractionated radiation exposure.
Topics: Animals; Cell Line, Tumor; Cell Survival; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Humans; K562 Cells; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Radiation Tolerance; Radiotherapy; Tetrazolium Salts; Thiazoles; U937 Cells; X-Rays | 2010 |
Effects of adenoviral-mediated coexpression of bone morphogenetic protein-7 and insulin-like growth factor-1 on human periodontal ligament cells.
Topics: Adenoviridae; Alkaline Phosphatase; Animals; Biomarkers; Bone Morphogenetic Protein 7; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Coculture Techniques; Collagen Type I; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Escherichia coli; Gene Transfer Techniques; Humans; Insulin-Like Growth Factor I; Mice; Osteogenesis; Periodontal Ligament; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Subcutaneous Tissue; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Transfection; Transgenes; Up-Regulation | 2010 |
Liv.52 attenuate copper induced toxicity by inhibiting glutathione depletion and increased antioxidant enzyme activity in HepG2 cells.
Topics: Antioxidants; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Copper; DNA Fragmentation; Drug Combinations; Glutathione; Humans; Lipid Peroxidation; Medicine, Ayurvedic; Plant Extracts; Tetrazolium Salts; Thiazoles | 2010 |
Magnesium modulates amyloid-beta protein precursor trafficking and processing.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Blotting, Western; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Extracellular Space; Immunoprecipitation; Magnesium; Mass Spectrometry; Mice; Microscopy, Confocal; Protein Processing, Post-Translational; Receptors, Cell Surface; Tetrazolium Salts; Thiazoles | 2010 |
shRNA interference for extracellular signal-regulated kinase 2 can inhibit the growth of esophageal cancer cell line Eca109.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Esophageal Neoplasms; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 2; Microscopy, Fluorescence; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
AF-2364 is a prospective spermicide candidate.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Survival; Cyclosporine; Drug Therapy, Combination; Humans; Hydrazines; Indazoles; Male; Mice; Mitochondria; Permeability; Seminal Plasma Proteins; Sperm Motility; Spermatocidal Agents; Spermatozoa; Tetrazolium Salts; Thiazoles | 2010 |
Limitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenols.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Female; Flavonoids; Humans; Inhibitory Concentration 50; Male; Phenols; Polyphenols; Reagent Kits, Diagnostic; Tea; Tetrazolium Salts; Thiazoles | 2010 |
The mechanism of vitexin-4''-O-glucoside protecting ECV-304 cells against tertbutyl hydroperoxide induced injury.
Topics: Analysis of Variance; Cell Line; Cell Survival; Crataegus; Drugs, Chinese Herbal; Flavones; Glucosides; Humans; In Situ Nick-End Labeling; Isoflavones; Lipid Peroxidation; Membrane Potential, Mitochondrial; Microscopy, Phase-Contrast; Molecular Structure; Plant Extracts; Plant Leaves; Rhodamine 123; Superoxide Dismutase; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles | 2010 |
Hydroxylation of diosgenin by Absidia coerulea.
Topics: Absidia; Antineoplastic Agents, Phytogenic; Biotransformation; Carbohydrate Sequence; Coloring Agents; Diosgenin; Drug Screening Assays, Antitumor; Humans; Hydroxylation; Indicators and Reagents; K562 Cells; KB Cells; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Tetrazolium Salts; Thiazoles | 2010 |
Water-retentive and anti-inflammatory properties of organic and inorganic substances from Korean sea mud.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Balneology; Body Water; Cell Line; Cell Survival; Coloring Agents; Dinoprostone; Geologic Sediments; Humans; Humic Substances; Inorganic Chemicals; Korea; Mass Spectrometry; Organic Chemicals; Radiation-Protective Agents; Skin; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2010 |
Sensitivity of morphological change of Vero cells exposed to lipophilic compounds and its mechanism.
Topics: Animals; Carbon; Cell Membrane; Cell Proliferation; Cell Shape; Chlorocebus aethiops; Chlorophenols; DNA; Environmental Pollutants; Flow Cytometry; Lipids; Membrane Proteins; Organic Chemicals; Phospholipids; Tetrazolium Salts; Thiazoles; Vero Cells; Water Pollutants, Chemical | 2010 |
A modulatory effect of novel kojic acid derivatives on cancer cell proliferation and macrophage activation.
Topics: Animals; Antineoplastic Agents; Antioxidants; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Coloring Agents; DNA Fragmentation; Glioma; Immunoprecipitation; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Nitric Oxide; Pyrones; Rats; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4 | 2010 |
Platelet-rich fibrin membranes as scaffolds for periosteal tissue engineering.
Topics: Adult; Alveolar Ridge Augmentation; Biocompatible Materials; Blood Platelets; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Collagen; Cytological Techniques; Fibrin; Fluoresceins; Humans; L-Lactate Dehydrogenase; Membranes, Artificial; Microscopy, Electron, Scanning; Periosteum; Propidium; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2010 |
Recombinant human midkine stimulates proliferation of articular chondrocytes.
Topics: Animals; Bromodeoxyuridine; Cartilage, Articular; Cell Proliferation; Cells, Cultured; Chondrocytes; Coloring Agents; Humans; Male; Mice; Mice, Inbred C57BL; Midkine; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2010 |
In-vitro study of cellular viability and nitric oxide production by J774 macrophages stimulated by interferon gamma with ceramic, polycarbonate, and polyoxymethylene brackets.
Topics: Animals; Cell Line; Cell Survival; Ceramics; Coloring Agents; Dental Materials; Interferon-gamma; Macrophage Activation; Macrophages; Materials Testing; Mice; Nitric Oxide; Orthodontic Brackets; Polycarboxylate Cement; Resins, Synthetic; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chalcones; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Humans; Male; Membrane Potentials; Mitochondrial Membranes; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Cytotoxic effects of White-MTA and MTA-Bio cements on odontoblast-like cells (MDPC-23).
Topics: Aluminum Compounds; Calcium Compounds; Cell Count; Cell Culture Techniques; Cell Line; Cell Shape; Cell Survival; Coloring Agents; Culture Media; Dental Cements; Drug Combinations; Humans; Materials Testing; Microscopy, Electron, Scanning; Odontoblasts; Oxides; Porosity; Root Canal Filling Materials; Silicates; Spectrophotometry; Succinate Dehydrogenase; Surface Properties; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Proliferation and differentiation potential of pluripotent mesenchymal precursor C2C12 cells on resin-based restorative materials.
Topics: Alkaline Phosphatase; Animals; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Composite Resins; Dental Restoration, Permanent; Glass Ionomer Cements; Hydroxybenzoate Ethers; Hydroxybenzoates; Mesenchymal Stem Cells; Mice; Mice, Inbred C3H; Pluripotent Stem Cells; Regeneration; Resin Cements; Tetrazolium Salts; Thiazoles; Tissue Scaffolds; Zinc Oxide-Eugenol Cement | 2010 |
Comparison of Er,Cr:YSGG laser and hand instrumentation on the attachment of periodontal ligament fibroblasts to periodontally diseased root surfaces: an in vitro study.
Topics: Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Proliferation; Coloring Agents; Curettage; Dental Cementum; Dental Scaling; Fibroblasts; Humans; Lasers, Solid-State; Microscopy, Confocal; Microscopy, Electron, Scanning; Periodontal Diseases; Periodontal Ligament; Root Planing; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Root | 2010 |
Effects of enamel matrix derivative on the viability, cytokine secretion, and phagocytic activity of human monocytes.
Topics: Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coloring Agents; Cytokines; Dental Enamel Proteins; Escherichia coli; Humans; Interleukin-1beta; Lipopolysaccharides; Monocytes; Phagocytosis; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Anticancer effect and structure-activity analysis of marine products isolated from metabolites of mangrove fungi in the South China Sea.
Topics: Antineoplastic Agents; Cell Line, Tumor; China; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fungi; Humans; Neoplasms; Rhizophoraceae; Seawater; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2010 |
Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay.
Topics: Anthralin; Anti-Infective Agents, Local; Caspase 3; Caspase 7; Cell Line; Cell Proliferation; Colorimetry; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; Fluorometry; Humans; Keratinocytes; Methotrexate; Psoriasis; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Thymidine | 2010 |
Up-regulation of heme oxygenase-1 protects against cold injury-induced brain damage: a laboratory-based study.
Topics: Adenoviridae; Animals; Behavior, Animal; Blood-Brain Barrier; Blotting, Western; Brain Damage, Chronic; Brain Edema; Cell Survival; Cold Temperature; Coloring Agents; Endothelial Cells; Fluorescent Antibody Technique; Heme Oxygenase-1; Humans; Male; Mice; Mice, Inbred ICR; Neutrophil Infiltration; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Dura in the pathogenesis of syndromic craniosynostosis: fibroblast growth factor receptor 2 mutations in dural cells promote osteogenic proliferation and differentiation of osteoblasts.
Topics: Acrocephalosyndactylia; Adenoviridae; Alkaline Phosphatase; Animals; Arginine; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coculture Techniques; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Craniofacial Dysostosis; Craniosynostoses; Cysteine; Dura Mater; Genetic Vectors; Mice; Osteoblasts; Osteogenesis; Osteopontin; Phenylalanine; Point Mutation; Receptor, Fibroblast Growth Factor, Type 2; Syndrome; Tetrazolium Salts; Thiazoles | 2010 |
DOX-loaded PEG-PLGA and Pluronic copolymer composite micelles enhances cytotoxicity and the intracellular accumulation of drug in DOX-resistant tumor cells.
Topics: Antibiotics, Antineoplastic; Cell Survival; Chemistry, Pharmaceutical; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Humans; K562 Cells; Micelles; Microscopy, Electron, Transmission; Particle Size; Poloxamer; Polyethylene Glycols; Polyglactin 910; Tetrazolium Salts; Thiazoles | 2010 |
miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1.
Topics: beta Catenin; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; High Mobility Group Proteins; Humans; MicroRNAs; Neoplasm Invasiveness; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Wnt Proteins | 2011 |
P2Y2 receptor-Gq/11 signaling at lipid rafts is required for UTP-induced cell migration in NG 108-15 cells.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Blotting, Western; Cell Line; Cell Movement; Cholesterol; Coloring Agents; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; L-Lactate Dehydrogenase; Membrane Microdomains; Peptides, Cyclic; Phosphatidylinositols; Phosphorylation; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; rho GTP-Binding Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Uridine Triphosphate | 2010 |
The establishment and characterization of adriamycin-resistant cell lines derived from Saos-2.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Inhibitory Concentration 50; Methotrexate; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2010 |
Adenovirus-mediated delivery of shRNA against bFGF mRNA suppresses growth of cultured human primary prostatic stromal cells.
Topics: Apoptosis; Base Sequence; Caspase 3; Cell Proliferation; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Male; Molecular Sequence Data; Prostate; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stromal Cells; Tetrazolium Salts; Thiazoles | 2011 |
Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.
Topics: Animals; Azabicyclo Compounds; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Indoles; Lung; Male; Mice; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Telemetry; Tetrazolium Salts; Thiazoles; Thymidine; Treatment Outcome | 2010 |
Ex vivo cytotoxicity of a new calcium silicate-based canal filling material.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Cell Culture Techniques; Cell Death; Cell Line; Coloring Agents; Diffusion; Drug Combinations; Epoxy Resins; Fibroblasts; Mice; Micropore Filters; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
The neuroprotective effect of erythropoietin-transduced human mesenchymal stromal cells in an animal model of ischemic stroke.
Topics: Animals; Antigens, CD; Brain Infarction; Caspase 3; Cell Death; Cell Line; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Flow Cytometry; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Lentivirus; Magnetic Resonance Imaging; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Nerve Growth Factors; Nervous System Diseases; Rats; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2010 |
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
Topics: Antioxidants; Coloring Agents; Formazans; Free Radical Scavengers; Mitochondria; Molecular Structure; NADP; Oxidation-Reduction; Plant Extracts; Singlet Oxygen; Tetrazolium Salts; Thiazoles | 2010 |
Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury.
Topics: Analysis of Variance; Animals; Astrocytoma; Brain; Cell Line, Tumor; Creatine Kinase; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Male; Methylmercury Compounds; Mice; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Effect of temperature and storage media on human periodontal ligament fibroblast viability.
Topics: Animals; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media; Fibroblasts; Humans; Isotonic Solutions; Milk; Organ Preservation Solutions; Periodontal Ligament; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Preservation; Trypan Blue; Water | 2010 |
Neuroprotective effects of emodin in rat cortical neurons against beta-amyloid-induced neurotoxicity.
Topics: Amyloid beta-Peptides; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Emodin; Enzyme Activation; Enzyme Inhibitors; Female; Flow Cytometry; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Targeted killing effects of double CD and TK suicide genes controlled by survivin promoter on gastric cancer cell.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosine Deaminase; Genes, Reporter; Genetic Therapy; Genetic Vectors; Humans; Inhibitor of Apoptosis Proteins; Plasmids; Promoter Regions, Genetic; Stomach Neoplasms; Survivin; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transgenes | 2011 |
Involvement of p300 in constitutive and HIV-1 Tat-activated expression of glial fibrillary acidic protein in astrocytes.
Topics: Astrocytes; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; E1A-Associated p300 Protein; Early Growth Response Protein 1; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; HIV Infections; Humans; RNA, Small Interfering; tat Gene Products, Human Immunodeficiency Virus; Tetrazolium Salts; Thiazoles; Thymidine; Transcriptional Activation; Transfection; Tritium; Up-Regulation | 2010 |
Cytotoxic effects of resin-modified orthodontic band adhesives. Are they safe?
Topics: Animals; Biocompatible Materials; Bisphenol A-Glycidyl Methacrylate; Cell Count; Cell Line; Cell Shape; Cell Survival; Coloring Agents; Composite Resins; Fibroblasts; Glass Ionomer Cements; Materials Testing; Mice; Mitochondria; Orthodontic Brackets; Resin Cements; Safety; Succinate Dehydrogenase; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Synthesis and antileishmanial activity of 5-(5-nitroaryl)-2-substituted-thio-1,3,4-thiadiazoles.
Topics: Antiprotozoal Agents; Cell Culture Techniques; Humans; Inhibitory Concentration 50; Leishmania major; Leishmaniasis; Nitro Compounds; Structure-Activity Relationship; Tetrazolium Salts; Thiadiazoles; Thiazoles | 2011 |
Synthesis and antiproliferative activities against Hep-G2 of salicylanide derivatives: potent inhibitors of the epidermal growth factor receptor (EGFR) tyrosine kinase.
Topics: Aniline Compounds; Antineoplastic Agents; ErbB Receptors; Fluorouracil; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Binding; Salicylanilides; Salicylates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2011 |
Online monitoring of cellular metabolism in the MCF-7 carcinoma cell line treated with phytoestrogen extracts.
Topics: Biosensing Techniques; Cell Adhesion; Cell Line, Tumor; Computational Biology; Equipment Design; Flax; Gene Expression Regulation; Humans; Metabolism; Oligonucleotide Array Sequence Analysis; Oxygen Consumption; Phytoestrogens; Plant Extracts; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Antioxidant and pro-oxidant properties of acylated pelargonidin derivatives extracted from red radish (Raphanus sativus var. niger, Brassicaceae).
Topics: Acylation; Anthocyanins; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Benzothiazoles; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; DNA Damage; Free Radical Scavengers; Humans; Iron Chelating Agents; Plant Extracts; Plant Roots; Plasmids; Raphanus; Reactive Oxygen Species; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2010 |
The compound cis-(dichloro)tetrammineruthenium(III) chloride induces caspase-mediated apoptosis in K562 cells.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle; Cell Survival; Cyclosporine; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Ruthenium Compounds; Tetrazolium Salts; Thiazoles; Trypan Blue; Tumor Stem Cell Assay | 2010 |
The roles of the thioredoxin system and peroxiredoxins in 1-methyl-4-phenyl-pyridinium ion-induced cytotoxicity in rat pheochromocytoma cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Lipid Peroxidation; Membrane Potential, Mitochondrial; Oxidation-Reduction; PC12 Cells; Peroxiredoxins; Pheochromocytoma; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Superoxides; Tetrazolium Salts; Thiazoles; Thioredoxins; Tumor Stem Cell Assay | 2010 |
In vitro behavior of MC3T3-E1 preosteoblast with different annealing temperature titania nanotubes.
Topics: 3T3 Cells; Animals; Anthraquinones; Biocompatible Materials; Calcification, Physiologic; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cell Shape; Cell Survival; Coloring Agents; Crystallization; Crystallography; Fluorine; Hot Temperature; Materials Testing; Mice; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanotubes; Osteoblasts; Photoelectron Spectroscopy; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; X-Ray Diffraction | 2010 |
Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi.
Topics: Animals; Brugia malayi; Coloring Agents; Disease Models, Animal; Elephantiasis, Filarial; Female; Filaricides; Flavanones; Flavonoids; Gerbillinae; Hesperidin; Humans; Male; Murinae; Rutin; Survival Analysis; Tetrazolium Salts; Thiazoles | 2010 |
Andrographolide sensitizes Ras-transformed cells to radiation in vitro and in vivo.
Topics: Animals; Annexin A5; Apoptosis; Caspase 3; Cell Line, Transformed; Coloring Agents; Diterpenes; DNA Fragmentation; Down-Regulation; Genes, ras; Mice; Mice, Nude; NF-kappa B; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; ras Proteins; Rats; RNA Nucleotidyltransferases; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous | 2010 |
D-Maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue.
Topics: Animals; Calcium Channels; Cell Membrane; CHO Cells; Circular Dichroism; Cricetinae; Cricetulus; Fluoresceins; Magnetic Resonance Spectroscopy; Microscopy, Confocal; Peptide Hydrolases; Peptides; Ryanodine; Scorpion Venoms; Tetrazolium Salts; Thiazoles | 2010 |
An improved 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction assay for evaluating the viability of Escherichia coli cells.
Topics: Bacteriological Techniques; Coloring Agents; Escherichia coli; Microbial Viability; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2010 |
The non-core regions of human lysozyme amyloid fibrils influence cytotoxicity.
Topics: Amyloid; Cell Line; Cell Survival; Humans; Microscopy, Electron, Transmission; Muramidase; Neurons; Protein Stability; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2010 |
Effect of bioaggregate on mineral-associated gene expression in osteoblast cells.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Calcium Hydroxide; Cell Count; Cell Proliferation; Cell Survival; Collagen Type I; Coloring Agents; Drug Combinations; Durapatite; Materials Testing; Mice; Minerals; Osteoblasts; Osteocalcin; Osteopontin; Oxides; Polymerase Chain Reaction; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles | 2010 |
Toxicity of Flow Line, Durafill VS, and Dycal to dental pulp cells: effects of growth factors.
Topics: Adult; Amino Acid Chloromethyl Ketones; Antioxidants; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Calcium Hydroxide; Caspase Inhibitors; Cell Death; Cell Survival; Cells, Cultured; Chromans; Coloring Agents; Composite Resins; Dental Materials; Dental Pulp; Drug Tolerance; Epidermal Growth Factor; Fibroblast Growth Factor 2; Humans; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Materials Testing; Minerals; Oxidative Stress; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta | 2010 |
In vitro osteogenic potential of an experimental calcium silicate-based root canal sealer.
Topics: 3T3 Cells; Alkaline Phosphatase; Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Cell Survival; Coloring Agents; Culture Media, Conditioned; Drug Combinations; Epoxy Resins; Extracellular Matrix; Materials Testing; Mice; Microscopy, Electron, Transmission; Minerals; Osteoblasts; Osteogenesis; Oxides; Root Canal Filling Materials; Silicates; Silver Staining; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors; Zinc Oxide-Eugenol Cement | 2010 |
Somatostatin receptor activation (sst(1) -sst(5) ) differentially influences human retinal pigment epithelium cell viability.
Topics: Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Growth Hormone; Humans; Ligands; Necrosis; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Receptors, Somatostatin; Retinal Pigment Epithelium; Tetrazolium Salts; Thiazoles; Trypan Blue; Vanadates | 2010 |
Association of dopamine DA-D2 receptor in rotenone-induced cytotoxicity in PC12 cells.
Topics: Animals; Glutathione; Insecticides; L-Lactate Dehydrogenase; PC12 Cells; Rats; Receptors, Dopamine D2; Rotenone; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2010 |
Dental pulp fibroblasts express neuropeptide Y Y1 receptor but not neuropeptide Y.
Topics: Blotting, Western; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Caries; Dental Pulp; Fibroblasts; Humans; Interleukin-1beta; Membrane Proteins; Neuroimmunomodulation; Neuropeptide Y; Receptors, Neuropeptide Y; Reverse Transcriptase Polymerase Chain Reaction; Substance P; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 2010 |
Biological effects and comparative cytotoxicity of thermal transformed asbestos-containing materials in a human alveolar epithelial cell line.
Topics: Alveolar Epithelial Cells; Apoptosis; Asbestos, Serpentine; Cell Line, Transformed; Cell Proliferation; Cell Survival; Ceramics; Construction Materials; Hot Temperature; Humans; Ki-67 Antigen; Microscopy, Electron, Scanning; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Lycopene prevents 3-nitropropionic acid-induced mitochondrial oxidative stress and dysfunctions in nervous system.
Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; Behavior, Animal; Brain Chemistry; Carotenoids; Coloring Agents; Female; Lipid Peroxidation; Lycopene; Maze Learning; Mitochondria; Nervous System; Nitrites; Nitro Compounds; Oxidative Stress; Permeability; Postural Balance; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2010 |
The role of heme oxygenase-1 in the proliferation and odontoblastic differentiation of human dental pulp cells.
Topics: Alkaline Phosphatase; Anthraquinones; Calcification, Physiologic; Carbon Monoxide; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Coloring Agents; Dental Pulp; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix Proteins; Free Radical Scavengers; Heme Oxygenase-1; Humans; Integrin-Binding Sialoprotein; Iron Chelating Agents; Metalloporphyrins; Odontoblasts; Osteopontin; Phosphoproteins; Protoporphyrins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Transforming growth factor beta1-induced heat shock protein 27 activation promotes migration of mouse dental papilla-derived MDPC-23 cells.
Topics: Animals; Blotting, Western; Cell Count; Cell Line; Cell Movement; Cell Proliferation; Chemotaxis; Coloring Agents; Dental Papilla; Enzyme Inhibitors; HSP27 Heat-Shock Proteins; Imidazoles; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2010 |
Differential and stereoselective in vitro cytotoxicity of eremophilane sesquiterpenes of Petasites hybridus rhizomes in rat hepatocytes.
Topics: Animals; Cell Membrane; Cell Respiration; Cytotoxins; Energy Metabolism; Hepatocytes; Naphthalenes; Petasites; Polycyclic Sesquiterpenes; Rats; Rhizome; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2011 |
Antimycobacterial screening of traditional medicinal plants using the microplate resazurin assay.
Topics: Antitubercular Agents; Drug Evaluation, Preclinical; Humans; Microbial Sensitivity Tests; Microbial Viability; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; Oxazines; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Xanthenes | 2010 |
Effect of in vitro exposure to zinc on immunological parameters of haemocytes from the marine gastropod Haliotis tuberculata.
Topics: Acid Phosphatase; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Environmental Pollutants; Esterases; Flow Cytometry; France; Gastropoda; Hemocytes; In Vitro Techniques; Lethal Dose 50; Models, Immunological; Monophenol Monooxygenase; Phagocytosis; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Zinc | 2010 |
Activity of the julocrotine, a glutarimide alkaloid from Croton pullei var. glabrior, on Leishmania (L.) amazonensis.
Topics: Alkaloids; Animals; Antiprotozoal Agents; Colorimetry; Croton; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Leishmania; Macrophages; Mice; Microbial Viability; Microscopy, Electron, Transmission; Organelles; Parasitology; Piperidones; Tetrazolium Salts; Thiazoles | 2010 |
Synthesis, antitumor, and DNA binding behavior of novel 4-(2-hydroxyquinolin-3-yl)-6-phenyl-5, 6 dihydropyrimidin derivatives in aqueous medium.
Topics: Absorption; Aldehydes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chalcones; DNA; Female; Humans; Hydroxyquinolines; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nucleic Acid Denaturation; Pyrimidines; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Tetrazolium Salts; Thiazoles; Viscosity; Water | 2010 |
Characterization and in vitro cellular uptake of PEG coated iron oxide nanoparticles as MRI contrast agent.
Topics: Animals; Cell Survival; Contrast Media; Ferric Compounds; Humans; KB Cells; Macrophages; Magnetic Resonance Imaging; Mice; Molecular Weight; Nanoparticles; Oleic Acid; Pharmaceutic Aids; Polyethylene Glycols; Tetrazolium Salts; Thiazoles | 2010 |
Study of the effectiveness of propolis extract as a storage medium for avulsed teeth.
Topics: Animals; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Dogs; Humans; Incisor; Isotonic Solutions; Male; Milk; Organ Preservation Solutions; Periodontal Ligament; Plant Extracts; Propolis; Radiography; Root Resorption; Saliva; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Apex; Tooth Avulsion; Tooth Replantation; Water | 2010 |
Effect of phloroglucinol on oxidative stress and inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blotting, Western; Cell Line; Coloring Agents; DNA Damage; Glutathione; Humans; Inflammation Mediators; Macrophages; Membrane Proteins; Mice; Nuclear Proteins; Oxidation-Reduction; Oxidative Stress; Phloroglucinol; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Upregulation of peripubertal rat Leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine.
Topics: Androgens; Animals; Atrazine; Cell Survival; Cells, Cultured; Cyclic AMP; Gonadal Steroid Hormones; Herbicides; Leydig Cells; Male; Phosphoproteins; Progesterone; Rats; Rats, Wistar; Sexual Maturation; Steroid 17-alpha-Hydroxylase; Steroidogenic Factor 1; Testosterone; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K/Akt and ERK1/2 pathways.
Topics: Animals; Apoptosis; Extracellular Signal-Regulated MAP Kinases; HSP90 Heat-Shock Proteins; Hypoxia; Male; Mesenchymal Stem Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Tetrazolium Salts; Thiazoles | 2010 |
Analysis of glial secretome: the long pentraxin PTX3 modulates phagocytic activity of microglia.
Topics: Acute-Phase Proteins; Animals; Animals, Newborn; Apoptosis; C-Reactive Protein; Cell Survival; Cells, Cultured; Chromatography, Liquid; Coculture Techniques; Computational Biology; Cricetinae; Cricetulus; Gene Expression Regulation; Green Fluorescent Proteins; Interferon-gamma; Lipocalin-2; Lipocalins; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microglia; Neuroblastoma; Oncogene Proteins; Phagocytes; Prosencephalon; Proteomics; Serum Amyloid P-Component; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
Long-acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway.
Topics: Aldehydes; Animals; Antioxidants; Blotting, Western; Cell Death; Cell Line; Chromatin; Coloring Agents; Cysteine Proteinase Inhibitors; Heme Oxygenase-1; Humans; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Iridoid Glycosides; Iridoids; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Response Elements; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
HSP25 affects the proliferation and differentiation of rat dental follicle cells.
Topics: Alkaline Phosphatase; Ameloblasts; Animals; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Coloring Agents; Cytoplasm; Dental Sac; Flow Cytometry; Fluorescent Antibody Technique, Indirect; HSP27 Heat-Shock Proteins; Odontoblasts; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tooth Germ; Up-Regulation | 2009 |
Manufacture and cytotoxicity of a lead-free piezoelectric ceramic as a bone substitute-consolidation of porous lithium sodium potassium niobate by cold isostatic pressing.
Topics: Animals; Biocompatible Materials; Bone Substitutes; Cell Adhesion; Cell Proliferation; Cells, Cultured; Ceramics; Coloring Agents; Electrochemistry; Materials Testing; Microscopy, Electron, Scanning; Niobium; Osteoblasts; Oxides; Porosity; Potassium; Pressure; Rats; Rats, Sprague-Dawley; Skull; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thiazoles | 2009 |
Effects of sangre de drago in an in vitro model of cutaneous neurogenic inflammation.
Topics: Animals; Capsaicin; Cells, Cultured; Coculture Techniques; Croton; Dermatitis; Drug Evaluation, Preclinical; Immunoenzyme Techniques; Keratinocytes; Male; Neurogenic Inflammation; Phytotherapy; Plant Extracts; Sensory Receptor Cells; Sensory System Agents; Substance P; Swine; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2010 |
Mo(II) complexes: a new family of cytotoxic agents?
Topics: 1-Octanol; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Molybdenum; Neoplasms; Neuroblastoma; Nucleic Acid Conformation; Phenanthrolines; Tetrazolium Salts; Thiazoles; Water | 2010 |
Potentiation of bortezomib-induced apoptosis by TGF-beta in cultured human Tenon's fibroblasts: contribution of the PI3K/Akt signaling pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Boronic Acids; Bortezomib; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flow Cytometry; Gene Expression Regulation; Genes, bcl-2; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tenon Capsule; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2010 |
Apoptosis of human lung adenocarcinoma A549 cells induced by prodigiosin analogue obtained from an entomopathogenic bacterium Serratia marcescens.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bombyx; Cell Line, Tumor; Cell Survival; Cluster Analysis; DNA, Bacterial; DNA, Ribosomal; Humans; Inhibitory Concentration 50; Lung Neoplasms; Molecular Sequence Data; Phylogeny; Prodigiosin; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Serratia marcescens; Tetrazolium Salts; Thiazoles; Time Factors | 2010 |
Platelets enhance activity of antimycotic substances against non-Aspergillus fumigatus Aspergillus species in vitro.
Topics: Antifungal Agents; Aspergillosis; Aspergillus; Blood Platelets; Humans; Microbial Viability; Tetrazolium Salts; Thiazoles | 2011 |
Melt processing of chitosan-based fibers and fiber-mesh scaffolds for the engineering of connective tissues.
Topics: Butylene Glycols; Cell Adhesion; Cell Line, Tumor; Cell Survival; Chitosan; Connective Tissue Cells; Freezing; Humans; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Porosity; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; X-Ray Microtomography | 2010 |
Microbicidal and cytotoxic effects of functional water in vitro.
Topics: Alkalies; Alkaline Phosphatase; Candida albicans; Cell Culture Techniques; Cell Proliferation; Cell Survival; Colony Count, Microbial; Coloring Agents; Dental Pulp; Disinfectants; Enterococcus faecalis; Humans; Hydrogen Peroxide; Hypochlorous Acid; Root Canal Irrigants; Sodium Hypochlorite; Tetrazolium Salts; Thiazoles; Water | 2010 |
Induction of arginase II mRNA by nitric oxide using an in vitro model of gyrate atrophy of choroid and retina.
Topics: Animals; Arginase; Boronic Acids; Cell Line; Enzyme Inhibitors; Gyrate Atrophy; Humans; Models, Biological; Nitric Oxide; Ornithine; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Swine; Tetrazolium Salts; Thiazoles; Up-Regulation | 2011 |
Protective effect of montelukast against quinolinic acid/malonic acid induced neurotoxicity: possible behavioral, biochemical, mitochondrial and tumor necrosis factor-α level alterations in rats.
Topics: Acetates; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Catalase; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Gene Expression Regulation; Lipid Peroxidation; Male; Malonates; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrites; Quinolines; Quinolinic Acid; Rats; Rats, Wistar; Sulfides; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2010 |
Protective effects of transduced PEP-1-Frataxin protein on oxidative stress-induced neuronal cell death.
Topics: Animals; Astrocytes; Blood-Brain Barrier; CA1 Region, Hippocampal; Cell Death; Cell Line, Tumor; Coloring Agents; Cysteamine; Dose-Response Relationship, Drug; Frataxin; Genetic Vectors; Gerbillinae; Humans; Iron-Binding Proteins; Ischemic Attack, Transient; Microscopy, Fluorescence; Neurons; Neuroprotective Agents; Oxidative Stress; Peptides; Rats; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2010 |
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2010 |
Multiresponse strategies to modulate burst degradation and release from nanoparticles.
Topics: Animals; Cell Line; Cells, Cultured; Esters; Hydrogen-Ion Concentration; Inflammation; Light; Materials Testing; Mice; Models, Chemical; Nanoparticles; Nanotechnology; Polymers; Scattering, Radiation; Solubility; Surface Properties; Tetrazolium Salts; Thiazoles | 2010 |
Composition, antimicrobial activity and in vitro cytotoxicity of essential oil from Cinnamomum zeylanicum Blume (Lauraceae).
Topics: Acrolein; Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Apoptosis; Benzaldehydes; Cell Line; Cell Survival; Cinnamates; Cinnamomum zeylanicum; Fibroblasts; Gas Chromatography-Mass Spectrometry; Microbial Sensitivity Tests; Oils, Volatile; Plant Bark; Plant Oils; Rats; Tetrazolium Salts; Thiazoles | 2010 |
Novel rhodanine derivatives induce growth inhibition followed by apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; L-Lactate Dehydrogenase; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Rhodanine; Tetrazolium Salts; Thiazoles; Trypan Blue | 2010 |
A new CoFe(2)O(4)-Cr(2)O(3)-SiO(2) fluorescent magnetic nanocomposite.
Topics: Cell Survival; Chromium; Cobalt; Drug Delivery Systems; Ferric Compounds; Fluorescent Dyes; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanocomposites; Nanotechnology; Silicon Dioxide; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2010 |
Susceptibility of Mycobacterium tuberculosis to first-line antimycobacterial agents in a Brazilian hospital: assessing the utility of the tetrazolium (MTT) microplate assay.
Topics: Adult; Anti-Bacterial Agents; Coloring Agents; Cross-Sectional Studies; Female; Humans; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Retrospective Studies; Tetrazolium Salts; Thiazoles; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2010 |
A novel method for establishment and characterization of extrahepatic bile duct epithelial cells from mice.
Topics: Animals; Bile Ducts, Extrahepatic; Cell Culture Techniques; Epithelial Cells; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Tetrazolium Salts; Thiazoles | 2010 |
Cytotoxicity of denture adhesives.
Topics: Actins; Adhesives; Animals; Biocompatible Materials; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Coloring Agents; Culture Media; Cytoskeleton; Dental Cements; Denture Retention; Dosage Forms; Dose-Response Relationship, Drug; Fibroblasts; Fluorescent Dyes; Hydrogen-Ion Concentration; Maleates; Materials Testing; Mice; Microscopy, Confocal; Polyethylenes; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo.
Topics: Animals; Apoptosis; Behavior, Animal; Cell Death; Cells, Cultured; Coloring Agents; Fluorescent Dyes; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Matrix Metalloproteinases; Neurons; Neuroprotective Agents; Oxidants; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rhodamine 123; Tetrazolium Salts; Thiazoles; Xanthophylls | 2010 |
Delivering a hydrophobic anticancer drug for photodynamic therapy by amorphous formulation.
Topics: Benzimidazoles; Cell Death; Chemistry, Pharmaceutical; Coloring Agents; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Delivery Systems; Fluorescent Dyes; HeLa Cells; Humans; Micelles; Mitochondria; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Polysorbates; Quinones; Spectrometry, Fluorescence; Surface-Active Agents; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2010 |
Antimycin A-induced mitochondrial apoptotic cascade is mitigated by phenolic constituents of Phyllanthus amarus aqueous extract in Hep3B cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anti-Bacterial Agents; Antimycin A; Apoptosis; Apoptosis Inducing Factor; Bromodeoxyuridine; Cell Line; Coloring Agents; Cytochromes c; Deoxyguanosine; DNA, Mitochondrial; Flow Cytometry; Humans; In Vitro Techniques; Indicators and Reagents; Lipid Peroxidation; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Phenols; Phyllanthus; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2010 |
P2X7 receptors mediate deleterious renal epithelial-fibroblast cross talk.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Apoptosis; Cells, Cultured; Coculture Techniques; Fibroblasts; Kidney; Kidney Tubules, Proximal; Necrosis; Purinergic P2X Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P2X7; Signal Transduction; Tetrazoles; Tetrazolium Salts; Thiazoles | 2011 |
Comparison of MTT assay, flow cytometry, and RT-PCR in the evaluation of cytotoxicity of five prosthodontic materials.
Topics: Animals; Apoptosis; Base Sequence; bcl-2-Associated X Protein; Cell Line; Dental Materials; DNA Primers; Flow Cytometry; Mice; Prosthodontics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2010 |
Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.
Topics: Adult; Aspirin; Cell Proliferation; Collagen; Dinoprostone; Electromagnetic Fields; Enzyme Inhibitors; Female; Humans; Intervertebral Disc; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Tetrazolium Salts; Thiazoles | 2010 |
Cytotoxicity of Vibrio cholerae on Madin Darby Bovine Kidney cells.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cattle; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Coloring Agents; Culture Media; Enzyme-Linked Immunosorbent Assay; Kidney; Polymyxin B; Tetrazolium Salts; Thiazoles; Vero Cells; Vibrio cholerae | 2010 |
Synthesis, characterization and cytotoxicity studies of chitosan-coated tea polyphenols nanoparticles.
Topics: Chitosan; Chlorides; Flavonoids; Hep G2 Cells; Humans; Ions; Light; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Phenols; Polyphenols; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Tea; Tetrazolium Salts; Thiazoles | 2011 |
Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures.
Topics: Animals; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation; Granulins; Humans; Hydrogen Peroxide; Indoles; Intercellular Signaling Peptides and Proteins; Mice; N-Methylaspartate; Neurons; Oxidants; Pregnancy; Progranulins; Protein Transport; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
Knockdown of glycogen synthase kinase 3 beta attenuates 6-hydroxydopamine-induced apoptosis in SH-SY5Y cells.
Topics: Adrenergic Agents; Analysis of Variance; Apoptosis; Caspases; Cell Count; Cell Line, Tumor; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neuroblastoma; Oxidopamine; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Anti-cariogenic and anti-biofilms activity of Tunisian propolis extract and its potential protective effect against cancer cells proliferation.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Biofilms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Child, Preschool; Humans; Inhibitory Concentration 50; Mouth; Propolis; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2010 |
Early proliferation alteration and differential gene expression in human periodontal ligament cells subjected to cyclic tensile stress.
Topics: Adolescent; Apoptosis Regulatory Proteins; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Chemokine CCL2; Child; Cyclooxygenase 2; Early Growth Response Transcription Factors; Female; Flow Cytometry; Gene Expression; GTP-Binding Protein Regulators; Homeodomain Proteins; Humans; Intracellular Signaling Peptides and Proteins; Kruppel-Like Transcription Factors; Male; Membrane Proteins; Microarray Analysis; Periodontal Ligament; Reverse Transcriptase Polymerase Chain Reaction; Tensile Strength; Tetrazolium Salts; Thiazoles; Up-Regulation | 2011 |
Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction.
Topics: Acrolein; Antioxidants; Calcium; Cell Line; Cell Survival; Coloring Agents; DNA Damage; Glutathione; Glutathione Transferase; Humans; Indicators and Reagents; Macular Degeneration; Mitochondria; Neuroprotective Agents; NF-E2-Related Factor 1; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Protein Carbonylation; Retinal Pigment Epithelium; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2007 |
PCB congeners induced mitochondrial dysfunction in Vero cells.
Topics: Animals; Apoptosis; Cell Death; Cell Size; Chlorocebus aethiops; Coloring Agents; Environmental Pollutants; Indicators and Reagents; Membrane Potentials; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Membranes; Polychlorinated Biphenyls; Tetrazolium Salts; Thiazoles; Vero Cells | 2011 |
Expression of osteoclastogenesis inducers in a tissue model of periodontal ligament under compression.
Topics: Adolescent; Biocompatible Materials; Biomechanical Phenomena; Cell Culture Techniques; Cell Survival; Coloring Agents; Fibroblast Growth Factor 2; Fibroblasts; Gingiva; Humans; Interleukin-11; Interleukin-8; Lactic Acid; Microscopy, Fluorescence; Osteoclasts; Parathyroid Hormone-Related Protein; Periodontal Ligament; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RANK Ligand; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Scaffolds; Tooth Movement Techniques; Up-Regulation | 2011 |
Effect of HBSS storage time on human periodontal ligament fibroblast viability.
Topics: Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Culture Media; Drug Storage; Fibroblasts; Humans; Isotonic Solutions; Organ Preservation Solutions; Periodontal Ligament; Spectrophotometry; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Avulsion; Water | 2010 |
Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells.
Topics: Animals; Cell Line; Cell Survival; Culicidae; Dengue Virus; Humans; Membrane Glycoproteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; RNA, Viral; Tetrazolium Salts; Thiazoles; Viral Proteins; Virus Replication | 2010 |
Honey promotes angiogeneic activity in the rat aortic ring assay.
Topics: Administration, Cutaneous; Animals; Aorta; Biomass; Cytotoxicity Tests, Immunologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Honey; Humans; Neovascularization, Physiologic; Ointments; Osmosis; Rats; Skin Care; Tetrazolium Salts; Thiazoles; Umbilical Veins; Wound Healing; Wounds and Injuries | 2010 |
Mimicking disinfection and drying of biofilms in contaminated endoscopes.
Topics: Biofilms; Candida; Disinfectants; Disinfection; Endoscopes; Humans; Microbial Viability; Models, Biological; Peracetic Acid; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; Tetrazolium Salts; Thiazoles | 2010 |
In vitro anti-influenza virus activities of sulfated polysaccharide fractions from Gracilaria lemaneiformis.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dogs; Gracilaria; Humans; Influenza, Human; Orthomyxoviridae; Plant Extracts; Polysaccharides; Sulfates; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 2010 |
Pharmacologic concentrations of melatonin have diverse influence on differential expressions of angiogenic chemokine genes in different hepatocellular carcinoma cell lines.
Topics: Amidohydrolases; Amphotericin B; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line, Tumor; Chemokines; Coloring Agents; Down-Regulation; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Liver Neoplasms; Melatonin; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Up-Regulation | 2010 |
Experimental diabetes attenuates calcium mobilization and proliferative response in splenic lymphocytes from mice.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels, L-Type; Concanavalin A; Diabetes Mellitus, Experimental; Fura-2; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Male; Mice; Spleen; Tetrazolium Salts; Thiazoles; Verapamil | 2011 |
A cardiac glucoside with in vitro anti-HIV activity isolated from Elaeodendron croceum.
Topics: Anti-HIV Agents; Cardiac Glycosides; Celastraceae; Cell Line; Digitoxigenin; Humans; Inhibitory Concentration 50; South Africa; Tetrazolium Salts; Thiazoles; Transcription Factors | 2010 |
Shikonin inhibits tumor invasion via down-regulation of NF-κB-mediated MMP-9 expression in human ACC-M cells.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Adenoid Cystic; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Electrophoresis, Polyacrylamide Gel; Humans; I-kappa B Proteins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Naphthoquinones; Neoplasm Invasiveness; NF-kappa B; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Enhancement of DNA vaccine (P12A3C-pcDNA) efficacy against foot-and-mouth disease by coadministration of interleukin-18-expressing (IL18 pcDNA) plasmid in guinea-pigs.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Neutralizing; Antibodies, Viral; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Guinea Pigs; Interleukin-18; Leukocytes, Mononuclear; Male; Neutralization Tests; Plasmids; T-Lymphocyte Subsets; Tetrazolium Salts; Thiazoles; Vaccines, DNA; Viral Vaccines | 2010 |
Novel ceramic bone replacement material Osbone® in a comparative in vitro study with osteoblasts.
Topics: Alkaline Phosphatase; Bone Substitutes; Calcium Phosphates; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Ceramics; Coloring Agents; DNA; Durapatite; Humans; Integrin-Binding Sialoprotein; L-Lactate Dehydrogenase; Materials Testing; Microscopy, Electron, Scanning; Minerals; Osteoblasts; Osteogenesis; Osteonectin; Osteopontin; Porosity; Reverse Transcriptase Polymerase Chain Reaction; Surface Properties; Tetrazolium Salts; Thiazoles | 2011 |
Effects of sub-sonic vibration on the proliferation and maturation of 3T3-L1 cells.
Topics: 3T3-L1 Cells; Animals; Bromodeoxyuridine; Cell Proliferation; DNA Primers; Gene Expression Regulation; L-Lactate Dehydrogenase; Mice; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Triglycerides; Vibration | 2011 |
Unconjugated bilirubin modulates nitric oxide production via iNOS regulation.
Topics: Analysis of Variance; Animals; Bilirubin; DNA Primers; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Enzymologic; In Vitro Techniques; L-Lactate Dehydrogenase; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thiocarbamates; Tumor Necrosis Factor-alpha | 2010 |
Oligomeric proanthocyanidins from Rumex acetosa L. inhibit the attachment of herpes simplex virus type-1.
Topics: Adenoviridae; Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organ Culture Techniques; Plant Extracts; Proanthocyanidins; Rumex; Skin; Tetrazolium Salts; Thiazoles; Vero Cells; Viral Plaque Assay; Virus Attachment | 2011 |
Comparison of methods for measuring viable E. coli cells during cultivation: great differences in the early and late exponential growth phases.
Topics: Bacteriological Techniques; Colony Count, Microbial; Escherichia coli; Microbial Viability; Oxygen; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2011 |
Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation.
Topics: Animals; Antioxidants; Benzimidazoles; Blotting, Western; Cell Survival; Coloring Agents; Extracellular Signal-Regulated MAP Kinases; Fluorescent Dyes; Ginsenosides; Hydrogen Peroxide; I-kappa B Proteins; Neuroprotective Agents; NF-kappa B; PC12 Cells; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
Antiplasmodial activity of botanical extracts against Plasmodium falciparum.
Topics: Animals; Antimalarials; Cell Line; Cell Survival; Humans; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plant Extracts; Plants; Plasmodium falciparum; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2011 |
Protection of CHO cells by transfer of survivin driven by ovarian-specific promoter OSP-2.
Topics: Analysis of Variance; Animals; Apoptosis; Apoptosis Regulatory Proteins; CHO Cells; Cricetinae; Cricetulus; Drug-Related Side Effects and Adverse Reactions; Flow Cytometry; Gene Targeting; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Neoplasms; Promoter Regions, Genetic; Survivin; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Spectroscopic characterization and antiproliferative activity on HepG2 human hepatoblastoma cells of flavonoid C-glycosides from Petrorhagia velutina.
Topics: Antineoplastic Agents, Phytogenic; Caryophyllaceae; Drug Screening Assays, Antitumor; Flavonoids; Gas Chromatography-Mass Spectrometry; Glycosides; Hep G2 Cells; Humans; Italy; Luteolin; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plant Roots; Tetrazolium Salts; Thiazoles | 2010 |
Effect of N-acetyl cysteine on orthodontic primers cytotoxicity.
Topics: Acetylcysteine; Antioxidants; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Dentin-Bonding Agents; Dose-Response Relationship, Drug; Ethanol; Fibroblasts; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Gingiva; Humans; Hydrophobic and Hydrophilic Interactions; Methacrylates; Propidium; Reactive Oxygen Species; Resin Cements; Tetrazolium Salts; Thiazoles | 2011 |
Effects of iRoot SP on mineralization-related genes expression in MG63 cells.
Topics: Analysis of Variance; Calcification, Physiologic; Calcium Compounds; Cell Line; Collagen Type I; Coloring Agents; Epoxy Resins; Gene Expression; Humans; Integrin-Binding Sialoprotein; Osteoblasts; Osteocalcin; Osteopontin; RNA, Messenger; Root Canal Filling Materials; Silicate Cement; Silicates; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2010 |
Aripiprazole protects cortical neurons from glutamate toxicity.
Topics: Animals; Aripiprazole; Benzodiazepines; Cell Nucleus; Cerebral Cortex; Cytoprotection; Dopamine D2 Receptor Antagonists; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Molecular Imaging; Neurons; Neuroprotective Agents; Olanzapine; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolones; Rats; Receptor, Serotonin, 5-HT1A; Risperidone; Serotonin 5-HT1 Receptor Antagonists; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
A transmembrane glycoprotein, gp38, is a novel marker for immature hepatic progenitor cells in fetal mouse livers.
Topics: alpha-Fetoproteins; Animals; Biomarkers; Bromodeoxyuridine; DNA Primers; Fetus; Flow Cytometry; Keratin-19; Liver; Membrane Glycoproteins; Mice; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Tetrazolium Salts; Thiazoles; Wnt Proteins; Wnt3 Protein; Wnt3A Protein | 2011 |
Ethosomes for the delivery of anti-HSV-1 molecules: preparation, characterization and in vitro activity.
Topics: Acyclovir; Antiviral Agents; Cell Survival; Diffusion; Drug Compounding; Electrochemistry; Freeze Drying; Herpesvirus 1, Human; Microscopy, Electron, Scanning; Microsomes; Particle Size; Pharmaceutical Vehicles; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 2010 |
Albumin modulates docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma cell lines.
Topics: Albumins; Antineoplastic Agents; Antioxidants; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Coloring Agents; DNA, Neoplasm; Docosahexaenoic Acids; Free Radical Scavengers; Humans; Indicators and Reagents; Iron Chelating Agents; Oxidation-Reduction; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Induction of fetal hemoglobin and ABCB1 gene expression in 9-β-D-arabinofuranosylguanine-resistant MOLT-4 cells.
Topics: Antineoplastic Agents; Arabinonucleosides; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Resistance, Neoplasm; Enzyme Activation; Fetal Hemoglobin; Humans; Microarray Analysis; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tetrazolium Salts; Thiazoles | 2011 |
ERK mediates anti-apoptotic effect through phosphorylation and cytoplasmic localization of p21Waf1/Cip1/Sdi in response to DNA damage in normal human embryonic fibroblast (HEF) cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Fractionation; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Immunoprecipitation; Phosphorylation; Tetrazolium Salts; Thiazoles | 2011 |
A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro.
Topics: Apoptosis; Asbestos; Cell Death; Cell Proliferation; Cell Survival; Comet Assay; Dose-Response Relationship, Drug; Endocytosis; Epithelial Cells; Humans; Immunohistochemistry; Jurkat Cells; Lung; Micronucleus Tests; Microscopy, Electron, Transmission; Nanotubes, Carbon; Reactive Oxygen Species; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2011 |
Biocompatibility of tissue engineering constructions from porous polylactide carriers obtained by the method of selective laser sintering and bone marrow-derived multipotent stromal cells.
Topics: Animals; Bone Marrow Cells; Cell Adhesion; Flow Cytometry; Guided Tissue Regeneration; Hot Temperature; Humans; Immunophenotyping; Lasers; Male; Materials Testing; Microscopy, Electron, Scanning; Multipotent Stem Cells; Polyesters; Porosity; Rats; Stem Cell Transplantation; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2010 |
Effects of photodynamic exposure on endothelial cells in vitro.
Topics: Cell Survival; Endothelial Cells; Humans; In Vitro Techniques; Indoles; Laser Therapy; Microscopy, Fluorescence; Organometallic Compounds; Photochemotherapy; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2010 |
PKGIα inhibits the proliferation of cerebral arterial smooth muscle cell induced by oxyhemoglobin after subarachnoid hemorrhage.
Topics: Analysis of Variance; Animals; Cell Count; Cell Proliferation; Cells, Cultured; Cerebral Arteries; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Muscle Cells; Muscle, Smooth; Oxyhemoglobins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Ghrelin inhibits apoptosis induced by palmitate in rat aortic endothelial cells.
Topics: Analysis of Variance; Animals; Aorta; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Cell Survival; Chromones; Endothelial Cells; Fluorescence; Ghrelin; Morpholines; Oligopeptides; Palmitates; Rats; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2010 |
Analysis of osteoblastic gene expression in the early human mesenchymal cell response to a chemically modified implant surface: an in vitro study.
Topics: Acid Etching, Dental; Bone Marrow Cells; Cell Adhesion; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Etching; Dental Implants; Dental Materials; Extracellular Matrix; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Mesenchymal Stem Cells; Neovascularization, Physiologic; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteogenesis; Signal Transduction; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Titanium; Transcription, Genetic; Up-Regulation | 2011 |
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways.
Topics: Analysis of Variance; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glutamic Acid; Hypoxia; Interleukin-10; Neurons; Neurotoxins; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-18; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tyrosine | 2011 |
Differential effects of platelet rich plasma and washed platelets on the proliferation of mouse MSC cells.
Topics: Alkaline Phosphatase; Animals; Blood Platelets; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cyclooxygenase 2; DNA Primers; Enzyme-Linked Immunosorbent Assay; Humans; Mesenchymal Stem Cells; Mice; Platelet-Rich Plasma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2011 |
Sesquiterpenes from Chloranthus japonicus.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Humans; Magnoliopsida; Molecular Structure; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2011 |
The HIV type 1 protease L10I minor mutation decreases replication capacity and confers resistance to protease inhibitors.
Topics: Amino Acid Substitution; Cell Line; Cell Proliferation; Cell Survival; Drug Resistance, Viral; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation, Missense; Protein Conformation; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Virus Replication | 2011 |
Rad52 inactivation is synthetically lethal with BRCA2 deficiency.
Topics: BRCA2 Protein; Cell Line, Tumor; Cell Nucleus; Chromosomal Instability; Chromosome Aberrations; DNA Damage; Gene Expression Regulation, Neoplastic; Genetic Complementation Test; HeLa Cells; Humans; Microscopy, Fluorescence; Rad51 Recombinase; Rad52 DNA Repair and Recombination Protein; Tetrazolium Salts; Thiazoles | 2011 |
Lysophosphatidic acid acyltransferase β (LPAATβ) promotes the tumor growth of human osteosarcoma.
Topics: Acyltransferases; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; Gentian Violet; Humans; Lipids; Neoplasm Metastasis; Osteosarcoma; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2010 |
Biodegradable microfibers deliver the antitumor drug temozolomide to glioma C6 cells in vitro.
Topics: Antineoplastic Agents, Alkylating; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Delivery Systems; Excipients; Glioma; Humans; Microscopy, Electron, Scanning; Particle Size; Polypropylenes; Temozolomide; Tetrazolium Salts; Thiazoles | 2010 |
Effects of citalopram on serum deprivation induced PC12 cell apoptosis and BDNF expression.
Topics: Animals; Apoptosis; Bisbenzimidazole; Blotting, Western; Brain-Derived Neurotrophic Factor; Cell Cycle; Cell Survival; Citalopram; Coloring Agents; Culture Media, Serum-Free; Flow Cytometry; PC12 Cells; Rats; Reverse Transcriptase Polymerase Chain Reaction; Selective Serotonin Reuptake Inhibitors; Tetrazolium Salts; Thiazoles | 2010 |
Synthesis, electronic structure, DNA and protein binding, DNA cleavage, and anticancer activity of fluorophore-labeled copper(II) complexes.
Topics: Antineoplastic Agents; Binding, Competitive; Cell Death; Computational Biology; Copper; DNA; DNA Cleavage; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Protein Binding; Ribonucleases; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2011 |
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.
Topics: Adenosine Triphosphate; Age Factors; Aldehydes; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Glutamic Acid; Humans; Huntingtin Protein; Huntington Disease; Imaging, Three-Dimensional; In Situ Nick-End Labeling; Indoles; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Masoprocol; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria; Neostriatum; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Oxidative Stress; Synapses; Tetrazolium Salts; Thiazoles; Trinucleotide Repeat Expansion | 2011 |
Inhibition of NF-κB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cerebellum; Flow Cytometry; Humans; Lipopolysaccharides; Medulloblastoma; Neurons; NF-kappa B; Proline; Protein Array Analysis; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tetrazolium Salts; Thiazoles; Thiocarbamates; Time Factors | 2011 |
The protective effects of chitooligosaccharides against glucose deprivation-induced cell apoptosis in cultured cortical neurons through activation of PI3K/Akt and MEK/ERK1/2 pathways.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glucose; In Situ Nick-End Labeling; Membrane Potentials; Mitochondrial Membranes; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Oligosaccharides; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
Effect of platelet-rich plasma on dental stem cells derived from human impacted third molars.
Topics: Antigens, Surface; CD146 Antigen; Cell Proliferation; Cells, Cultured; Chemokine CCL5; Culture Media, Conditioned; Dental Pulp; Humans; Intercellular Adhesion Molecule-1; Molar; Periodontal Ligament; Platelet-Rich Plasma; Stem Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tooth, Impacted | 2011 |
Large-scale production, purification and bioactivity assay of recombinant human interleukin-6 in the methylotrophic yeast Pichia pastoris.
Topics: Cell Proliferation; Chemical Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dextrans; Gene Expression; Humans; Interleukin-6; Lymphocytes; Mass Spectrometry; Molecular Weight; Pichia; Polyethylene Glycols; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2011 |
A novel class of geldanamycin derivatives as HCV replication inhibitors targeting on Hsp90: synthesis, structure-activity relationships and anti-HCV activity in GS4.3 replicon cells.
Topics: Antiviral Agents; Benzoquinones; Cell Line; Cell Survival; Hepacivirus; Humans; Inhibitory Concentration 50; Lactams, Macrocyclic; Microbial Sensitivity Tests; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Virus Replication | 2011 |
Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Cytosol; Deoxyglucose; Hexokinase; Humans; Isoenzymes; Mitochondria; Neurons; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytosol; Dose-Response Relationship, Drug; Fluoresceins; Histocytochemistry; L-Lactate Dehydrogenase; Macrophages; Magnetite Nanoparticles; Mice; Microscopy, Electron, Transmission; Oxidative Stress; Particle Size; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2010 |
Analysis of coal tar pitch and smoke extract components and their cytotoxicity on human bronchial epithelial cells.
Topics: Bronchi; Cell Line; Cell Survival; Coal Tar; Coloring Agents; Dimethyl Sulfoxide; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Humans; Polycyclic Aromatic Hydrocarbons; Smoke; Tetrazolium Salts; Thiazoles | 2011 |
EPO attenuates inflammatory cytokines by Muller cells in diabetic retinopathy.
Topics: Animals; Cell Line; Cytokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Gene Expression Regulation; In Situ Nick-End Labeling; Interleukin-1beta; Interleukin-6; Luciferases; NF-kappa B; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
The effect of coptis chinensis on the signaling network in the squamous carcinoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Berberine; Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Computational Biology; Coptis; Cytoskeletal Proteins; Humans; Mice; Mice, Nude; Plant Extracts; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
Sodium thiosulfate exposure disrupts in vitro and in vivo heart development.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Line; Chick Embryo; Dose-Response Relationship, Drug; Embryonic Development; Environmental Exposure; Heart; In Situ Nick-End Labeling; Myocytes, Cardiac; Rats; Tetrazolium Salts; Thiazoles; Thiosulfates | 2011 |
Fatty acids derived from royal jelly are modulators of estrogen receptor functions.
Topics: Cell Line, Tumor; Estrogen Receptor alpha; Estrogen Receptor beta; Fatty Acids; HeLa Cells; Humans; Ligands; Models, Biological; Models, Molecular; Osteoblasts; Receptors, Estrogen; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Two-Hybrid System Techniques | 2010 |
miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress.
Topics: Analysis of Variance; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Feedback, Physiological; Female; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Luciferases; MicroRNAs; Plasmids; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2011 |
Long-term cultivation of primmorphs from freshwater Baikal sponges Lubomirskia baikalensis.
Topics: Animals; Aquaculture; Cell Culture Techniques; DNA Primers; Fresh Water; Models, Animal; Porifera; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Russia; Tetrazolium Salts; Thiazoles | 2011 |
Antiviral activity of recombinant cyanovirin-N against HSV-1.
Topics: Animals; Antiviral Agents; Bacterial Proteins; Biological Products; Carrier Proteins; Cell Survival; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Disease Models, Animal; DNA, Viral; Encephalitis, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Male; Mice; Recombinant Proteins; Survival Analysis; Tetrazolium Salts; Thiazoles; Vero Cells | 2010 |
Toxic effects of low alcohol and nicotine combinations in SH-SY5Y cells are apoptotically mediated.
Topics: Analysis of Variance; Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Combinations; Ethanol; Humans; Neuroblastoma; Nicotine; Nicotinic Agonists; Salsoline Alkaloids; Tetrazolium Salts; Thiazoles | 2011 |
The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study.
Topics: Apoptosis; Bone Density Conservation Agents; Cell Culture Techniques; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Clodronic Acid; Coloring Agents; Diphosphonates; Fluoresceins; Fluorescent Dyes; Humans; Ibandronic Acid; Imidazoles; In Situ Nick-End Labeling; Keratinocytes; Mouth Mucosa; Pamidronate; Tetrazolium Salts; Thiazoles; Zoledronic Acid | 2012 |
Atrazine exposure leads to altered growth of HepG2 cells.
Topics: Atrazine; Cell Cycle; Cell Proliferation; Cell Survival; Cyclins; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Herbicides; Humans; Tetrazolium Salts; Thiazoles | 2011 |
Standardization of biochemical profile of mesenchymal cell materials by probing the level of dehydrogenase activity.
Topics: Bone Marrow Cells; Cell Culture Techniques; Cells, Cultured; Female; Formazans; Humans; Mesenchymal Stem Cells; Oxidoreductases; Pregnancy; Tetrazolium Salts; Thiazoles | 2010 |
Antibacterial properties and human gingival fibroblast cell compatibility of TiO2/Ag compound coatings and ZnO films on titanium-based material.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Load; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Coated Materials, Biocompatible; Coloring Agents; Fibroblasts; Fluorescent Dyes; Gingiva; Humans; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Scanning; Organic Chemicals; Silver; Spectrometry, X-Ray Emission; Streptococcus mutans; Tetrazolium Salts; Thiazoles; Titanium; Wettability; Zinc Oxide | 2012 |
Upregulation of heme oxygenase-1 as an adaptive mechanism for protection against crotonaldehyde in human umbilical vein endothelial cells.
Topics: Adaptation, Physiological; Aldehydes; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Endothelial Cells; Female; Fluorescent Antibody Technique; Heme Oxygenase-1; Humans; In Vitro Techniques; Luciferases; NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Kinase C-delta; Reactive Oxygen Species; RNA; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Umbilical Veins; Up-Regulation | 2011 |
LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancer via death receptor pathway.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Morpholines; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Death Domain; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus.
Topics: Antiviral Agents; Cell Line; Cell Survival; Hepacivirus; Hepatocytes; Humans; Inhibitory Concentration 50; Pakistan; Plant Extracts; Seeds; Solanum nigrum; Tetrazolium Salts; Thiazoles | 2011 |
Correlation between the pharmacological efficacy of cyclosporine and tacrolimus as evaluated by the lymphocyte immunosuppressant sensitivity test (LIST) and the MTT assay procedure in patients before and after renal transplantation.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Lymphocytes; Tacrolimus; Tetrazolium Salts; Thiazoles | 2011 |
Effect of rare earth elements on beef cattle growth performance, blood clinical chemical parameters and mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro and ex vivo.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Chemical Analysis; Body Weight; Cattle; Cell Proliferation; Cell Separation; Coloring Agents; Growth; In Vitro Techniques; Male; Metals, Rare Earth; Mitogens; Monocytes; Tetrazolium Salts; Thiazoles; Weight Gain | 2011 |
Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell proliferation of pterygium fibroblasts.
Topics: Adult; Aged; Animals; Bromodeoxyuridine; Cyclin-Dependent Kinase Inhibitor p27; Female; Fibroblasts; Humans; Male; Middle Aged; Pterygium; Rabbits; RNA, Small Interfering; S-Phase Kinase-Associated Proteins; Tetrazolium Salts; Thiazoles | 2011 |
Phosphatidylinositol 3-kinase inhibitor LY294002 suppresses proliferation and sensitizes doxorubicin chemotherapy in bladder cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Doxorubicin; Humans; Inhibitory Concentration 50; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms | 2011 |
CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1.
Topics: Analysis of Variance; Astrocytes; Brain; CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fetus; Gene Expression Regulation; Glial Fibrillary Acidic Protein; HIV Infections; HIV-1; Humans; Promoter Regions, Genetic; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-1; Transfection | 2011 |
Synthesis and characterization of ionic charged water soluble arginine-based poly(ester amide).
Topics: Amides; Animals; Biocompatible Materials; Carboxylic Acids; DNA; Hydrogels; Hydrophobic and Hydrophilic Interactions; Ions; Models, Chemical; Myocytes, Smooth Muscle; Polyesters; Polymers; Rats; Solubility; Solvents; Tetrazolium Salts; Thiazoles; Transfection; Water | 2011 |
Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Catatonia; Cyclooxygenase 2 Inhibitors; Inflammation; Isoxazoles; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mitochondria; Motor Activity; MPTP Poisoning; NADH Dehydrogenase; Neuroprotective Agents; Nitrites; Nitrobenzenes; Oxidative Stress; Signal Transduction; Sulfhydryl Compounds; Sulfonamides; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Transcription Factor RelA | 2011 |
A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug.
Topics: Animals; Antihypertensive Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Cornea; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Glaucoma; Polyesters; Polymers; Porosity; Rabbits; Regression Analysis; Sulfonamides; Tetrazolium Salts; Thiazoles; Thiophenes; X-Ray Diffraction | 2011 |
Effect of curcumin and irradiation in PE/CA-PJ15 oral squamous cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Colorimetry; Coloring Agents; Curcumin; Humans; Mouth Neoplasms; Neoadjuvant Therapy; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase.
Topics: Adsorption; Butyrates; Catalysis; Chemistry, Pharmaceutical; Hydroxybutyrates; Ion Exchange Resins; Kinetics; L-Lactate Dehydrogenase; Pseudomonas; Tetrazolium Salts; Thiazoles | 2011 |
Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun.
Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Survival; Cells, Cultured; Epithelium, Corneal; Humans; Hypertonic Solutions; JNK Mitogen-Activated Protein Kinases; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Proteins | 2011 |
Cell activity analysis by capillary zone electrophoresis combined with specific cell staining.
Topics: Azo Compounds; Cell Proliferation; Colorimetry; Electrophoresis, Capillary; HeLa Cells; Humans; Methylmercury Compounds; Microscopy, Confocal; Neutral Red; Rhodamine 123; Staining and Labeling; Tetrazolium Salts; Thiazoles; Trypan Blue | 2011 |
Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit.
Topics: Alkaline Phosphatase; Amino Acid Transport System y+; Animals; Calcium; Cell Differentiation; Cell Proliferation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Gene Expression; Glutathione; Mice; Osteoblasts; Osteogenesis; Promoter Regions, Genetic; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2011 |
Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells.
Topics: Annexin A5; Antibodies, Monoclonal, Humanized; Apoptosis; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Flow Cytometry; Glioma; Humans; Platelet Endothelial Cell Adhesion Molecule-1; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor C; Vascular Endothelial Growth Factor D | 2011 |
Dynamic oxidoreductive potential of astringent retraction agents.
Topics: Alum Compounds; Aluminum Chloride; Aluminum Compounds; Astringents; Cell Survival; Cells, Cultured; Chlorides; Coloring Agents; Ferric Compounds; Fibroblasts; Gingiva; Humans; Oxidation-Reduction; Tetrazolium Salts; Thiazoles | 2010 |
ADAM28 manipulates proliferation, differentiation, and apoptosis of human dental pulp stem cells.
Topics: ADAM Proteins; Adolescent; Adult; Alkaline Phosphatase; Annexin A5; Apoptosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Pulp; Disintegrins; Extracellular Matrix Proteins; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Genetic Vectors; Humans; Integrin-Binding Sialoprotein; Lipids; Male; Membrane Glycoproteins; Oligodeoxyribonucleotides, Antisense; Phosphoproteins; Plasmids; Propidium; Sialoglycoproteins; Stem Cells; Tetrazolium Salts; Thiazoles; Transfection; Young Adult | 2011 |
Effect of novel chitosan-fluoroaluminosilicate glass ionomer cement with added transforming growth factor beta-1 on pulp cells.
Topics: Adolescent; Alkaline Phosphatase; Aluminum Compounds; Biocompatible Materials; Calcification, Physiologic; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Coloring Agents; Dental Pulp; Drug Carriers; Fluorides; Glass Ionomer Cements; Humans; Materials Testing; Serum Albumin, Bovine; Silicon Compounds; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2011 |
Cytotoxicity comparison of mineral trioxide aggregates and EndoSequence bioceramic root repair materials.
Topics: Aluminum Compounds; Anti-Infective Agents, Local; Biocompatible Materials; Calcium Compounds; Calcium Phosphates; Cell Death; Cell Survival; Cells, Cultured; Chlorhexidine; Coloring Agents; Culture Media; Drug Combinations; Fibroblasts; Humans; Materials Testing; Oxides; Root Canal Filling Materials; Silicates; Skin; Tantalum; Tetrazolium Salts; Thiazoles; Time Factors; Zirconium | 2011 |
The effect of substrate topography on hFOB cell behavior and initial cell adhesion evaluated by a cytodetacher.
Topics: Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cell Survival; Cytological Techniques; Equipment Design; Humans; Microscopy, Electron, Scanning; Osteoblasts; Shear Strength; Silicon; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2011 |
Pro-apoptotic role of integrin β3 in glioma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Etoposide; Flow Cytometry; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glioma; Humans; Integrin beta3; Nitric Oxide; Rats; RNA, Messenger; Signal Transduction; Statistics as Topic; Tetrazolium Salts; Thiazoles; Vitronectin | 2011 |
Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001.
Topics: Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Eukaryotic Initiation Factor-4E; Everolimus; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; Jurkat Cells; Lymphoma; Models, Biological; Phosphorylation; Proto-Oncogene Proteins c-akt; Sirolimus; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2011 |
Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate.
Topics: Autophagy; Blotting, Western; Cell Line; Coloring Agents; Diphosphonates; DNA; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Imidazoles; Immunoprecipitation; Octoxynol; Polyethylene Glycols; Polyisoprenyl Phosphates; Protein Prenylation; Tetrazolium Salts; Thiazoles; Zoledronic Acid | 2011 |
Impairment of oxidative stress-induced heme oxygenase-1 expression by the defect of Parkinson-related gene of PINK1.
Topics: 1-Methyl-4-phenylpyridinium; Adenoviridae; Benzimidazoles; Blotting, Western; Cell Line; Cell Survival; Cloning, Molecular; Coloring Agents; Dopamine; Fluorescent Antibody Technique; Fluorescent Dyes; Gene Expression Regulation; Genetic Vectors; Heme Oxygenase-1; HSP90 Heat-Shock Proteins; Humans; L-Lactate Dehydrogenase; Mutation; Oxidative Stress; Parkinson Disease, Secondary; Protein Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2011 |
Optimizing PANi doped electroactive substrates as patches for the regeneration of cardiac muscle.
Topics: Aniline Compounds; Biocompatible Materials; Cell Survival; Electric Conductivity; Electrochemistry; Humans; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Models, Chemical; Myocardium; Polyesters; Polymers; Regeneration; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2011 |
Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspase 9; Cell Death; Cell Line; Coloring Agents; Ferric Compounds; Glutathione; Humans; Indicators and Reagents; Inhibitor of Apoptosis Proteins; L-Lactate Dehydrogenase; Nanoparticles; Neutral Red; Nickel; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Survivin; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2011 |
Potential of the propolis as storage medium to preserve the viability of cultured human periodontal ligament cells: an in vitro study.
Topics: Animals; Cell Culture Techniques; Cell Survival; Coloring Agents; Culture Media; Humans; Isotonic Solutions; Materials Testing; Milk; Neutral Red; Organ Preservation Solutions; Periodontal Ligament; Propolis; Saliva, Artificial; Specimen Handling; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2011 |
Inhibition of cytokine expression by a butanol extract from Cordyceps bassiana.
Topics: Animals; Blotting, Western; Butanols; Coloring Agents; Cordyceps; Cytokines; Genes, Reporter; Humans; Interferon-gamma; Interleukin-12; Interleukin-4; Lipopolysaccharides; Lymphocytes; Macrophages; Mice; p38 Mitogen-Activated Protein Kinases; Plant Extracts; RNA, Messenger; Signal Transduction; Solvents; Spleen; Tetrazolium Salts; Thiazoles; Transcription Factors; Tumor Necrosis Factor-alpha | 2011 |
The osteogenetic effect of astragaloside IV with centrifugating pressure on the OCT-1 cells.
Topics: Alkaline Phosphatase; Animals; Cell Line; Centrifugation; Collagen Type I; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Fluorescent Antibody Technique; Osteocalcin; Osteogenesis; Posture; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes | 2011 |
Biological effects of lentivirus-mediated shRNA targeting collagen type I on the mesangial cells of rats.
Topics: Animals; Apoptosis; Cell Cycle; Collagen Type I; Genetic Vectors; Green Fluorescent Proteins; Lentivirus; Male; Mesangial Cells; Nephrosclerosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Light filtering in a retinal pigment epithelial cell culture model.
Topics: Cell Line; Colorimetry; Coloring Agents; Filtration; Humans; Light; Polycarboxylate Cement; Radiation Injuries; Retinal Pigment Epithelium; Tetrazolium Salts; Thiazoles | 2011 |
AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers.
Topics: alpha-Synuclein; Animals; Astrocytes; Cell Death; Cell Survival; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Electrophysiological Phenomena; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Hippocampus; Humans; Iron; Mice; Microscopy, Confocal; Patch-Clamp Techniques; Receptors, AMPA; Recombinant Proteins; Synaptic Transmission; Tetrazolium Salts; Thiazoles | 2011 |
The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress.
Topics: Antineoplastic Agents; Autophagy; Benzoquinones; Cell Line, Tumor; Culture Media, Serum-Free; Electron Transport; Gene Knockout Techniques; Glycolysis; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; RNA Interference; Sirtuin 1; Stress, Physiological; Superoxides; Tetrazolium Salts; Thiazoles | 2011 |
Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Arachidonic Acid; Calcium; Catechin; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Glycoproteins; L-Lactate Dehydrogenase; N-Methylaspartate; NADPH Oxidases; Neurons; Neuroprotective Agents; Oxazines; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2011 |
Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells.
Topics: Anti-Bacterial Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Endoplasmic Reticulum; Glycosylation; HeLa Cells; Humans; Mitochondria; Mouth Neoplasms; Oxidative Stress; Prions; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tunicamycin | 2011 |
Green tea polysaccharide-conjugates protect human umbilical vein endothelial cells against impairments triggered by high glucose.
Topics: Amino Acid Sequence; Cell Survival; Chemical Fractionation; Chromatography, Gel; Dose-Response Relationship, Drug; Endothelial Cells; Free Radical Scavengers; Glucose; Humans; Plant Extracts; Plant Proteins; Polysaccharides; Reactive Oxygen Species; Tea; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2011 |
Optimization of sulfated modification conditions of tremella polysaccharide and effects of modifiers on cellular infectivity of NDV.
Topics: Animals; Basidiomycota; Chick Embryo; Fibroblasts; Newcastle disease virus; Polysaccharides; Specific Pathogen-Free Organisms; Sulfates; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Virus Integration | 2011 |
The underlying biological mechanisms of biocompatibility differences between bare and TiN-coated NiTi alloys.
Topics: Alloys; Anti-Inflammatory Agents; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Endothelial Cells; Flow Cytometry; Humans; Ions; Materials Testing; Microscopy, Electron, Scanning; Nickel; Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Titanium; Umbilical Veins | 2011 |
Design and synthesis of novel camptothecin/5-fluorouracil conjugates as cytotoxic agents.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Fluorouracil; Humans; Inhibitory Concentration 50; Lactones; Mice; Molecular Structure; Tetrazolium Salts; Thiazoles | 2011 |
Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway.
Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebral Cortex; Coumarins; Drug Interactions; Enzyme Inhibitors; Glucose; Hypoxia; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Rats; Reperfusion; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
The high expression level of programmed death-1 ligand 2 in oral lichen planus and the possible costimulatory effect on human T cells.
Topics: Antibodies; Antigen Presentation; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniques; Coloring Agents; Epithelium; Humans; Immunohistochemistry; Interferon-gamma; Interleukin-2; Keratinocytes; Lichen Planus, Oral; Lymphocyte Activation; Mouth Mucosa; Phytohemagglutinins; Programmed Cell Death 1 Ligand 2 Protein; Real-Time Polymerase Chain Reaction; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2011 |
Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Collagen Type VI; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Hippocampus; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Neurites; Neurons; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Signal Transduction; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2011 |
Statins regulate interleukin-1β-induced RANKL and osteoprotegerin production by human gingival fibroblasts.
Topics: Atorvastatin; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Serum-Free; Fibroblasts; Gingiva; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Osteoprotegerin; Pyrroles; RANK Ligand; Simvastatin; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Molecular structure, expression and bioactivity characterization of TNF13B (BAFF) gene in mefugu, Takifugu obscurus.
Topics: Amino Acid Sequence; Animals; B-Cell Activating Factor; B-Lymphocytes; Base Sequence; Blotting, Western; Cluster Analysis; Computational Biology; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flow Cytometry; Gene Components; Green Fluorescent Proteins; Mice; Microscopy, Confocal; Models, Molecular; Molecular Sequence Data; Organ Specificity; Phylogeny; Polymerase Chain Reaction; Protein Conformation; Sequence Analysis, DNA; Spleen; Takifugu; Tetrazolium Salts; Thiazoles | 2011 |
In vitro inhibitory effect of trichostatin A on canine grade 3 mast cell tumor.
Topics: Acetylation; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dogs; Female; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mast-Cell Sarcoma; Mice; Mice, Nude; Tetrazolium Salts; Thiazoles; Trypan Blue | 2011 |
Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway.
Topics: Amyloid beta-Peptides; Animals; Annexin A5; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation; Isoflavones; Neuroprotective Agents; Oncogene Protein v-akt; PC12 Cells; Peptide Fragments; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2011 |
In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
Topics: Amidines; Animals; Antiprotozoal Agents; Cell Survival; Cells, Cultured; Humans; Inhibitory Concentration 50; Mice; Microscopy; Myocytes, Cardiac; Parasitic Sensitivity Tests; Tetrazolium Salts; Thiazoles; Trypanosoma cruzi | 2011 |
Involvement of endoplasmic reticulum stress in adenosine-induced human hepatoma HepG2 cell apoptosis.
Topics: Adenosine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases, Initiator; Cell Proliferation; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Hep G2 Cells; Humans; Liver Neoplasms; Tetrazolium Salts; Thiazoles; Transcription Factor CHOP | 2011 |
Amphotericin B is cytotoxic at locally delivered concentrations.
Topics: Amphotericin B; Animals; Antifungal Agents; BALB 3T3 Cells; Biofilms; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Mice; Osteoblasts; Tetrazolium Salts; Thiazoles | 2011 |
Synthesis of a natural gamma-butyrolactone from nerylacetone by Acremonium roseum and Fusarium oxysporum cultures.
Topics: 4-Butyrolactone; Acetone; Acremonium; Biotransformation; Cell Line, Tumor; Chromatography, Gas; Drug Screening Assays, Antitumor; Fusarium; Humans; Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2011 |
Celecoxib inhibits interleukin-6/interleukin-6 receptor-induced JAK2/STAT3 phosphorylation in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; DNA; Humans; Immunohistochemistry; Interleukin-6; Janus Kinase 2; Liver Neoplasms; Microscopy, Fluorescence; Phosphorylation; Pyrazoles; Receptors, Interleukin-6; STAT3 Transcription Factor; Sulfonamides; Tetrazolium Salts; Thiazoles | 2011 |
Identification of ELAVL4 as a modulator of radiation sensitivity in A549 non-small cell lung cancer cells.
Topics: Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Separation; DNA Damage; ELAV Proteins; ELAV-Like Protein 4; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Radiation Tolerance; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2011 |
Changes in 2-fluoro-2-deoxy-D-glucose incorporation, hexokinase activity and lactate production by breast cancer cells responding to treatment with the anti-HER-2 antibody trastuzumab.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Trastuzumab; Tumor Stem Cell Assay | 2011 |
Setting properties and cytotoxicity evaluation of a premixed bioceramic root canal sealer.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Calcium Phosphates; Cell Survival; Ceramics; Coloring Agents; Drug Combinations; Epoxy Resins; Hardness; Materials Testing; Mice; Osteoblasts; Oxides; Polytetrafluoroethylene; Root Canal Filling Materials; Silicates; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2011 |
Effects of nicotine on apoptosis in human gingival fibroblasts.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Culture Techniques; Cell Nucleus; Cell Survival; Coloring Agents; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fluoresceins; Fluorescent Dyes; Gingiva; Humans; In Situ Nick-End Labeling; Indoles; JNK Mitogen-Activated Protein Kinases; Nicotine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Inhibition of TNF-α/IFN-γ induced RANTES expression in HaCaT cell by naringin.
Topics: Anti-Inflammatory Agents; Cell Proliferation; Chemokine CCL5; Citrus; Epithelial Cells; Flavanones; Humans; Inflammation; Interferon-gamma; Keratinocytes; NF-kappa B; Phytotherapy; Plant Preparations; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2011 |
Sodium fluoride affects proliferation and apoptosis through insulin-like growth factor I receptor in primary cultured mouse osteoblasts.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Apoptosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Mice; Mice, Inbred BALB C; Osteoblasts; Real-Time Polymerase Chain Reaction; Receptor, IGF Type 1; RNA Interference; RNA, Messenger; Sodium Fluoride; Tetrazolium Salts; Thiazoles | 2011 |
Apatite forming ability and cytocompatibility of pure and Zn-doped bioactive glasses.
Topics: Apatites; Biocompatible Materials; Calcium; Cell Proliferation; Cell Survival; Glass; Hot Temperature; Humans; Ions; Kinetics; Magnetic Resonance Spectroscopy; Phosphates; Powders; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; X-Ray Diffraction; Zinc | 2011 |
Leishmania tropica: the effect of darkness and light on biological activities in vitro.
Topics: Animals; Carbohydrate Metabolism; Cell Cycle; Cell Line; Darkness; Flow Cytometry; Formazans; Leishmania tropica; Light; Macrophages; Mice; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles | 2011 |
Increased transforming growth factor-β2 in epidermal growth factor receptor variant III-positive glioblastoma.
Topics: Adult; Aged; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Interleukin-10; Male; Middle Aged; Neoplasm Invasiveness; RNA, Messenger; Sequence Deletion; Tetrazolium Salts; Thiazoles; Transfection; Transforming Growth Factor beta2 | 2011 |
Layer-by-layer nanoparticles with a pH-sheddable layer for in vivo targeting of tumor hypoxia.
Topics: Animals; Cell Line, Tumor; Electrolytes; Female; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hypoxia; Mice; Mice, Nude; Nanoparticles; Nanotechnology; Neoplasm Transplantation; Neoplasms; Particle Size; Polyethylene Glycols; Surface Properties; Tetrazolium Salts; Thiazoles | 2011 |
Cell sensitivity assays: the MTT assay.
Topics: Cell Culture Techniques; Cell Line; Cytotoxins; Drug-Related Side Effects and Adverse Reactions; Formazans; Humans; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2011 |
Amoebicidal activity and chemical composition of Pterocaulon polystachyum (Asteraceae) essential oil.
Topics: Acanthamoeba castellanii; Animals; Antiprotozoal Agents; Asteraceae; Cell Survival; Chlorocebus aethiops; Gas Chromatography-Mass Spectrometry; Oils, Volatile; Parasitic Sensitivity Tests; Plant Leaves; Staining and Labeling; Tetrazolium Salts; Thiazoles; Vero Cells | 2011 |
The effects of the iodinated X-ray contrast media iodixanol, iohexol, iopromide, and ioversol on the rat kidney epithelial cell line NRK 52-E.
Topics: Animals; Cell Death; Cell Line; Coloring Agents; Contrast Media; Epithelial Cells; Iohexol; Kidney; Rats; Tetrazolium Salts; Thiazoles; Triiodobenzoic Acids; Trypan Blue | 2011 |
Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse.
Topics: Animals; Apoptosis; Benzofurans; Caspase 3; Cells, Cultured; Cerebellum; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Environmental Pollutants; Indoles; Mice; Mice, Knockout; Neurons; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tetrazolium Salts; Thiazoles; Trypan Blue | 2011 |
Comprehensive comparison of two new biodegradable gene carriers.
Topics: Absorbable Implants; Aldehydes; Animals; Cross-Linking Reagents; Deoxyribonuclease I; Drug Carriers; Excipients; Female; Genetic Vectors; HEK293 Cells; Hep G2 Cells; Humans; Imines; Mice; Mice, Inbred BALB C; Particle Size; Plasmids; Polyethylene Glycols; Polyethylenes; Polymers; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
In vitro cytotoxic evaluation of processed natural coral in human osteoblasts.
Topics: Animals; Anthozoa; Apoptosis; Biocompatible Materials; Cell Adhesion; Cell Line; Flow Cytometry; Humans; Materials Testing; Neutral Red; Osteoblasts; Tetrazolium Salts; Thiazoles | 2011 |
Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cytochromes c; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Glutathione; Humans; Neuroblastoma; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Ubiquinone | 2011 |
Caudatin induces cell cycle arrest and caspase-dependent apoptosis in HepG2 cell.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cell Cycle Checkpoints; Cell Proliferation; Cynanchum; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Gene Expression Regulation; Glycosides; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Plant Roots; Proto-Oncogene Proteins c-bcl-2; Steroids; Tetrazolium Salts; Thiazoles | 2012 |
PDE4 inhibitor suppresses PGE2-induced osteoclast formation via COX-2-mediated p27(KIP1) expression in RAW264.7 cells.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Dinoprostone; Flow Cytometry; Indicators and Reagents; Macrophages; Mice; Osteoclasts; Phosphodiesterase 4 Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2011 |
Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Naphthoquinones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2011 |
Mineral trioxide aggregate promotes odontoblastic differentiation via mitogen-activated protein kinase pathway in human dental pulp stem cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Blotting, Western; Calcium Compounds; Cell Differentiation; Collagen Type I; Dental Pulp; Drug Combinations; Extracellular Matrix Proteins; Humans; Integrin-Binding Sialoprotein; Mitogen-Activated Protein Kinases; Odontoblasts; Osteocalcin; Oxides; Phosphoproteins; Phosphorylation; Real-Time Polymerase Chain Reaction; Sialoglycoproteins; Signal Transduction; Silicates; Stem Cells; Tetrazolium Salts; Thiazoles | 2012 |
Influence of nicotine on the biological activity of rabbit osteoblasts.
Topics: Animals; Bone Morphogenetic Protein 2; Cell Culture Techniques; Cell Proliferation; Coloring Agents; Neovascularization, Physiologic; Nicotine; Osteoblasts; Osteogenesis; Phenotype; Platelet-Derived Growth Factor; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2011 |
Endostar down-regulates HIF-1 and VEGF expression and enhances the radioresponse to human lung adenocarcinoma cancer cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cell Cycle; Cell Line, Tumor; Endostatins; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1; Lung Neoplasms; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2012 |
Downregulation of NIN/RPN12 binding protein inhibit the growth of human hepatocellular carcinoma cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Flow Cytometry; Genetic Vectors; Humans; Lentivirus; Liver Neoplasms; Mice; Mice, Nude; Nuclear Proteins; RNA-Binding Proteins; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2012 |
Hepatitis B virus induces G1 phase arrest by regulating cell cycle genes in HepG2.2.15 cells.
Topics: Animals; Cell Cycle Proteins; Cell Line; Cell Survival; Female; G1 Phase; Hepatitis B virus; Hepatocytes; Humans; Mice; Mice, Nude; Neoplasms; Staining and Labeling; Stem Cells; Tetrazolium Salts; Thiazoles | 2011 |
Electrochemical sensors, MTT and immunofluorescence assays for monitoring the proliferation effects of cissus populnea extracts on Sertoli cells.
Topics: Animals; Biosensing Techniques; Cell Proliferation; Cells, Cultured; Cissus; Electrochemistry; Fertility Agents, Male; Fluorescent Antibody Technique; Male; Plant Extracts; Rats; Sertoli Cells; Spermatogenesis; Tetrazolium Salts; Thiazoles | 2011 |
Organ-specific scaffolds for in vitro expansion, differentiation, and organization of primary lung cells.
Topics: Animals; Cell Differentiation; Cell Proliferation; Coculture Techniques; Hepatocytes; Humans; Liver; Lung; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Lew; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2011 |
The down-regulation of galectin-1 expression is a specific biomarker of arsenic toxicity.
Topics: 3T3 Cells; Animals; Antimony; Arsenic; Arsenic Poisoning; Biomarkers; Blotting, Western; Cadmium; Cell Cycle; Down-Regulation; Flow Cytometry; Galectin 1; Humans; KB Cells; Mice; Nickel; RNA Interference; Spectrophotometry, Atomic; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
Topics: Animals; Calcium; Cell Hypoxia; Cells, Cultured; Creatine Kinase; Dose-Response Relationship, Drug; Homeostasis; L-Lactate Dehydrogenase; Rats; Reperfusion Injury; Sarcoplasmic Reticulum; Sirolimus; Sodium-Calcium Exchanger; Tetrazolium Salts; Thiazoles; Thiourea; Time Factors | 2011 |
S100A4 mediated cell invasion and metastasis of esophageal squamous cell carcinoma via the regulation of MMP-2 and E-cadherin activity.
Topics: Blotting, Western; Cadherins; Carcinoma, Squamous Cell; DNA Primers; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Metastasis; Real-Time Polymerase Chain Reaction; S100 Calcium-Binding Protein A4; S100 Proteins; Tetrazolium Salts; Thiazoles | 2012 |
Gadolinium inhibits prostate cancer PC3 cell migration and suppresses osteoclast differentiation in vitro.
Topics: Animals; Apoptosis; Blotting, Western; Calcium; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Survival; Gadolinium; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Microscopy, Confocal; Osteoclasts; Phosphorylation; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Wound Healing | 2011 |
The combined effects of oncolytic reovirus plus Newcastle disease virus and reovirus plus parvovirus on U87 and U373 cells in vitro and in vivo.
Topics: Animals; Brain; Brain Neoplasms; Cell Death; Cell Line, Tumor; Culture Media; Disease Models, Animal; Female; Flow Cytometry; Glioma; Humans; Mice; Mice, SCID; Newcastle disease virus; Oncolytic Viruses; Parvovirus; Tetrazolium Salts; Thiazoles; Viral Load; Xenograft Model Antitumor Assays | 2011 |
Fluorescent gold nanoclusters as a biocompatible marker for in vitro and in vivo tracking of endothelial cells.
Topics: Animals; Aorta; Biocompatible Materials; Biomarkers; Cell Survival; Endothelial Cells; Fluorescent Dyes; Gene Expression Profiling; Gold; Humans; In Vitro Techniques; Ischemia; Metal Nanoparticles; Mice; Microscopy, Fluorescence; Neovascularization, Physiologic; Quantum Dots; Stem Cells; Tetrazolium Salts; Thiazoles | 2011 |
In vitro and in vivo evaluation of sanguinarine liposomes prepared by a remote loading method with three different ammonium salts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Compounding; Drug Screening Assays, Antitumor; Indicators and Reagents; Isoquinolines; Liposomes; Male; Microscopy, Electron, Transmission; Particle Size; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2011 |
Stavudine entrapped lipid nanoparticles for targeting lymphatic HIV reservoirs.
Topics: Animals; Anti-HIV Agents; Calorimetry, Differential Scanning; Cell Survival; Coloring Agents; Drug Compounding; Electrochemistry; Fluorescent Dyes; HIV; HIV Seropositivity; In Vitro Techniques; Lymphatic System; Macrophages; Male; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Particle Size; Rats; Rats, Wistar; Rhodamine 123; Stavudine; Tetrazolium Salts; Thiazoles; Tissue Distribution | 2011 |
The TRIF/TBK1/IRF-3 activation pathway is the primary inhibitory target of resveratrol, contributing to its broad-spectrum anti-inflammatory effects.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Nucleus; Cells, Cultured; Coloring Agents; Genes, Reporter; Inflammation; Interferon Regulatory Factor-3; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Plasmids; Protein Serine-Threonine Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Tetrazolium Salts; Thiazoles | 2011 |
Arbutin inhibits TCCSUP human bladder cancer cell proliferation via up-regulation of p21.
Topics: Actins; Arbutin; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Extracellular Signal-Regulated MAP Kinases; Gentian Violet; Humans; Neoplasm Proteins; Tetrazolium Salts; Thiazoles; Up-Regulation; Urinary Bladder Neoplasms | 2011 |
Novel scaffold design with multi-grooved PLA fibers.
Topics: Animals; Biocompatible Materials; Cell Survival; Fibroblasts; Lactic Acid; Materials Testing; Mice; Microscopy, Electron, Scanning; NIH 3T3 Cells; Photoelectron Spectroscopy; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tetrazolium Salts; Textiles; Thiazoles; Tissue Engineering | 2011 |
In vivo effect of three fractions of Larrea divaricata Cav. (jarilla) on the innate immune system: macrophage response against Candida albicans.
Topics: Animals; Apoptosis; Candida albicans; Cell Survival; Cells, Cultured; DNA Fragmentation; Ethidium; Female; Immunologic Factors; Larrea; Macrophages, Peritoneal; Male; Mice; Nitrites; Nitroblue Tetrazolium; Plant Extracts; Respiratory Burst; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2011 |
Inhibition activities of polysaccharide (RG4-1) from Gentiana rigescens against RSV.
Topics: Animals; Antiviral Agents; Child; Chlorocebus aethiops; Dose-Response Relationship, Drug; Gentiana; Humans; Infant; Polysaccharides; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Tetrazolium Salts; Thiazoles; Time Factors; Vero Cells; Virus Replication | 2011 |
Establishment of a primary pleomorphic xanthoastrocytoma cell line: in vitro responsiveness to some chemotherapeutics.
Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Count; Cell Proliferation; Drug Screening Assays, Antitumor; Glial Fibrillary Acidic Protein; Humans; Magnetic Resonance Imaging; Male; Primary Cell Culture; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Tumor Cells, Cultured | 2012 |
An in-vitro evaluation of the polo-like kinase inhibitor GW843682X against paediatric malignancies.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Benzimidazoles; Blotting, Western; Camptothecin; Caspases; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Child; Coloring Agents; Enzyme Activation; Enzyme Inhibitors; Humans; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thiophenes; Topoisomerase I Inhibitors | 2011 |
Polybrominated diphenyl ethers and polychlorinated dibenzo-p-dioxins and dibenzofurans in surface dust at an E-waste processing site in Southeast China.
Topics: Analysis of Variance; Benzofurans; Biological Assay; China; Computers; Cytochrome P-450 CYP1A1; Dioxins; Dust; Environmental Pollutants; Halogenated Diphenyl Ethers; Refuse Disposal; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2011 |
Nucleofection induces non-specific changes in the metabolic activity of transfected cells.
Topics: Analysis of Variance; Animals; Cell Line; Cell Nucleus; Cell Proliferation; Electroporation; Energy Metabolism; Flow Cytometry; Humans; Mice; Microscopy, Fluorescence; Oxazines; Oxidation-Reduction; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection; Xanthenes | 2012 |
Influence of carboxylic acid functionalization on the cytotoxic effects induced by single wall carbon nanotubes on human endothelial cells (HUVEC).
Topics: Carboxylic Acids; Cell Survival; Coloring Agents; Human Umbilical Vein Endothelial Cells; Humans; Nanotubes, Carbon; Neutral Red; Proteins; Tetrazolium Salts; Thiazoles | 2011 |
Curcumin attenuates aluminum-induced oxidative stress and mitochondrial dysfunction in rat brain.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aluminum; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Curcumin; Electron Transport Complex IV; Gene Expression Regulation; Glutathione; HSP72 Heat-Shock Proteins; Mitochondria; NADH Dehydrogenase; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2011 |
Analysis for the potential of polystyrene and TiO2 nanoparticles to induce skin irritation, phototoxicity, and sensitization.
Topics: 3T3 Cells; Animals; Cell Line; Cell Survival; Coloring Agents; Dermatitis, Phototoxic; Female; Fibroblasts; Humans; Hypersensitivity; In Vitro Techniques; Keratinocytes; Local Lymph Node Assay; Mice; Mice, Inbred CBA; Microscopy, Electron, Transmission; Nanoparticles; Neutral Red; Polystyrenes; Rabbits; Skin; Tetrazolium Salts; Thiazoles; Titanium; Toxicity Tests | 2011 |
siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Fluorescent Antibody Technique; Gene Expression Regulation; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Receptor, Notch1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
Down-regulation of β3-integrin inhibits bone metastasis of small cell lung cancer.
Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Colony-Forming Units Assay; Drug Combinations; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Integrin beta3; Laminin; Proteoglycans; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Small Cell Lung Carcinoma; Tetrazolium Salts; Thiazoles | 2012 |
Cytotoxic and antitumor effects of brucine on Ehrlich ascites tumor and human cancer cell line.
Topics: Animals; Antineoplastic Agents; Antioxidants; bcl-2-Associated X Protein; Blood Cell Count; Carcinoma, Ehrlich Tumor; Caspases; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Immunohistochemistry; Interleukin-12; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Oxidative Stress; Strychnine; Survival Analysis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
Natural resistance to apoptosis correlates with resistance to chemotherapy in colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Colorimetry; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
Treatment of experimental cerebral vasospasm by protein transduction of heme oxygenase 1 (HO-1) conjugated to a residue of 11 arginines.
Topics: Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Vasospasm, Intracranial | 2011 |
Aroclor1254 interferes with estrogen receptor-mediated neuroprotection against beta-amyloid toxicity in cholinergic SN56 cells.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Chlorodiphenyl (54% Chlorine); Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Fulvestrant; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Luciferases; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Neuroprotective Agents; Parasympathetic Nervous System; Phosphorylation; tau Proteins; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Atrazine induces transcriptional changes in marker genes associated with steroidogenesis in primary cultures of rat Leydig cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Atrazine; Cell Survival; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Coloring Agents; Estrogen Receptor alpha; Gene Expression Regulation; Herbicides; Insulin; Leydig Cells; Male; Neutral Red; Phosphoproteins; Proteins; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2011 |
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway.
Topics: Adenine Nucleotides; Amyloid beta-Peptides; Antineoplastic Agents, Phytogenic; Autophagy; Blotting, Western; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Electron Transport Complex IV; Enzyme Activation; Humans; Lysosomes; Microscopy, Confocal; Microtubules; Mitochondrial Diseases; Mitochondrial Membranes; NAD; Paclitaxel; Peptide Fragments; Signal Transduction; Tetrazolium Salts; Thiazoles; Tubulin | 2011 |
Zinc oxide nanoparticles as selective killers of proliferating cells.
Topics: Algorithms; Analysis of Variance; Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Finite Element Analysis; Flow Cytometry; Humans; Mesenchymal Stem Cells; Metal Nanoparticles; Microscopy, Electron, Scanning; Particle Size; Rats; Rats, Inbred WF; Reactive Oxygen Species; Spectrometry, X-Ray Emission; Tetrazolium Salts; Thiazoles; Zinc Oxide | 2011 |
Isothiocyanates from Broccolini seeds induce apoptosis in human colon cancer cells: proteomic and bioinformatic analyses.
Topics: Amino Acid Sequence; Antineoplastic Agents, Phytogenic; Apoptosis; Brassica; Cell Line, Tumor; Colonic Neoplasms; Coloring Agents; Computational Biology; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Humans; Image Processing, Computer-Assisted; Isothiocyanates; Molecular Sequence Data; Protein Hydrolysates; Proteins; Proteomics; Seeds; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Trypsin | 2011 |
Nevirapine nanosuspensions for HIV reservoir targeting.
Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; Chelating Agents; Coloring Agents; Disease Reservoirs; Electrochemistry; HIV-1; In Vitro Techniques; Infusions, Parenteral; Isotope Labeling; Kidney; Macrophages; Male; Mice; Microscopy, Atomic Force; Nanoparticles; Nevirapine; Particle Size; Permeability; Radionuclide Imaging; Rats; Solubility; Suspensions; Tetrazolium Salts; Thiazoles; Tissue Distribution; Urinary Bladder; X-Ray Diffraction | 2011 |
Inhibition of thioredoxin reductase by auranofin induces apoptosis in adriamycin-resistant human K562 chronic myeloid leukemia cells.
Topics: Antibiotics, Antineoplastic; Antirheumatic Agents; Apoptosis; Auranofin; Caspase 3; Cell Survival; Coloring Agents; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Humans; K562 Cells; Leukemia, Myeloid; Tetrazolium Salts; Thiazoles; Thioredoxin-Disulfide Reductase | 2011 |
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Blood Platelets; Brefeldin A; Caspase 3; Cell Death; Cell Fusion; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heat-Shock Proteins; Humans; Hybrid Cells; In Situ Nick-End Labeling; Male; Middle Aged; Mitochondria; Peptide Fragments; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Tetrazolium Salts; Thapsigargin; Thiazoles | 2012 |
Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from INCL patients.
Topics: Apoptosis; Cells, Cultured; Chromatography, Thin Layer; Codon, Nonsense; Codon, Terminator; Dose-Response Relationship, Drug; Enzyme Induction; Fluorescent Antibody Technique; Humans; Membrane Proteins; Microscopy, Electron, Transmission; Neuronal Ceroid-Lipofuscinoses; Oxadiazoles; Tetrazolium Salts; Thiazoles; Thiolester Hydrolases; Time Factors | 2011 |
Functional identification of a non-fusion TRAIL extracellular protein and preparation of its polyclonal antibody.
Topics: Animals; Antibodies; Apoptosis; Blotting, Western; Cell Proliferation; Chromatography, Ion Exchange; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flow Cytometry; Genetic Vectors; Humans; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand | 2011 |
A novel system for rapid screening of effective siRNA target sites by one step transfection with a single vector.
Topics: DNA Polymerase III; Genetic Vectors; Green Fluorescent Proteins; HeLa Cells; Humans; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Secretion of IL-1β triggered by dynasore in murine peritoneal macrophages.
Topics: Adenosine Triphosphate; Animals; Calcium; Caspase 1; Cells, Cultured; Coloring Agents; Hydrazones; Interleukin-1beta; L-Lactate Dehydrogenase; Macrophages, Peritoneal; Male; Mice; Mice, Knockout; Potassium; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Tetrazolium Salts; Thiazoles | 2012 |
Molecular mechanism of silymarin-induced apoptosis in a highly metastatic lung cancer cell line anip973.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mitochondria; Neoplasm Metastasis; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Silymarin; Tetrazolium Salts; Thiazoles | 2011 |
The tight junction, intercellular seal as a cell signaling player: protocols for examination of its status.
Topics: Apoptosis; Blotting, Western; Cell Culture Techniques; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Claudins; Colony-Forming Units Assay; Female; Humans; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Microarray Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Tight Junctions | 2011 |
Growth-inhibitory effect of neurotrophin-3-secreting adipose tissue-derived mesenchymal stem cells on the D283-MED human medulloblastoma cell line.
Topics: Adipose Tissue; Autophagy; beta-Galactosidase; Blotting, Western; Brain Neoplasms; Cell Differentiation; Cell Movement; Cell Separation; Coculture Techniques; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; In Situ Nick-End Labeling; Medulloblastoma; Mesenchymal Stem Cells; Neurotrophin 3; Plasmids; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2012 |
Cytotoxicity of 45S5 bioglass paste used for dentine hypersensitivity treatment.
Topics: Animals; Biocompatible Materials; Calcium Sulfate; Cell Count; Cell Line; Cell Survival; Ceramics; Coloring Agents; Dental Cements; Dental Pulp; Dentin Desensitizing Agents; Glass; Glass Ionomer Cements; Hydrogen-Ion Concentration; Materials Testing; Oxalic Acid; Phosphoric Acids; Rats; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Vinyl Compounds; Zinc Oxide | 2011 |
Role of vimentin in the inhibitory effects of low-molecular-weight heparin on PC-3M cell adhesion to, and migration through, endothelium.
Topics: Blotting, Western; Calcium; Cell Adhesion; Cell Movement; Cell Survival; Cells, Cultured; Coloring Agents; Electrophoresis, Gel, Two-Dimensional; Endothelium, Vascular; Fluorescent Antibody Technique; Heparin, Low-Molecular-Weight; Humans; Male; Microscopy, Electron, Scanning; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Vimentin | 2011 |
Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Cell Line, Tumor; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Doxycycline; Drug Interactions; Gene Expression Regulation; Green Fluorescent Proteins; Heme Oxygenase-1; Herbicides; Humans; Levodopa; Membrane Potentials; Mice; Nerve Tissue Proteins; Neuroblastoma; Paraquat; Patch-Clamp Techniques; Permeability; Tetrazolium Salts; Thiazoles; Transfection; Tubulin; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2011 |
Cytotoxicity of composite resins before and after expiration date. Preliminary report.
Topics: Animals; Coloring Agents; Composite Resins; Drug Storage; Fibroblasts; L Cells; Mice; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Simultaneous administration of fluoride and selenite regulates proliferation and apoptosis in murine osteoblast-like MC3T3-E1 cells by altering osteoprotegerin.
Topics: 3T3 Cells; Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Proliferation; Coloring Agents; Flow Cytometry; Fluorides; Mice; Osteoblasts; Osteoprotegerin; RANK Ligand; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Sodium Selenite; Tetrazolium Salts; Thiazoles | 2011 |
A polypeptide from shark troponin I can inhibit angiogenesis and tumor growth.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chromatography, Affinity; Cloning, Molecular; DNA Primers; Endothelial Cells; Escherichia coli; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neovascularization, Physiologic; Peptides; Sequence Analysis, DNA; Sequence Homology; Sharks; Species Specificity; Tetrazolium Salts; Thiazoles; Troponin I | 2012 |
Cellular response to the deposition of diesel exhaust particle aerosols onto human lung cells grown at the air-liquid interface by inertial impaction.
Topics: Aerosols; Air Pollutants; Atmosphere Exposure Chambers; Cell Line, Tumor; Cell Survival; Equipment Design; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; L-Lactate Dehydrogenase; Lung; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Toxicity Tests; Vehicle Emissions | 2011 |
Effect of Fasciola hepatica proteins on the functioning of rat hepatocytes.
Topics: Animals; Cell Membrane Permeability; Cell Survival; Culture Media; Enzymes; Fasciola hepatica; Helminth Proteins; Hepatocytes; Male; Metabolic Networks and Pathways; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2012 |
Improving the interferences of methyl thiazolyl tetrazolium and IL-8 assays in assessing the cytotoxicity of nanoparticles.
Topics: 2-Propanol; Adsorption; Biological Assay; Cell Line, Tumor; Cell Survival; Dimethyl Sulfoxide; Humans; Interleukin-8; Metal Nanoparticles; Spectrophotometry; Tetrazolium Salts; Thiazoles; Titanium; Toxicity Tests; Zinc Oxide | 2011 |
The cytotoxicity and anticancer mechanisms of alterporriol L, a marine bianthraquinone, against MCF-7 human breast cancer cells.
Topics: Alternaria; Anthraquinones; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
H2S releasing aspirin protects amyloid beta induced cell toxicity in BV-2 microglial cells.
Topics: Amyloid beta-Peptides; Animals; Aspirin; Cell Line, Transformed; Cell Survival; Cyclooxygenase 2; Dose-Response Relationship, Drug; Hydrogen Sulfide; Lactate Dehydrogenases; Membrane Potential, Mitochondrial; Mice; Microglia; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protective Agents; Tetrazolium Salts; Thiazoles; Transcription Factor CHOP; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Biocompatibility of two novel root repair materials.
Topics: Aluminum Compounds; Biocompatible Materials; Calcium Compounds; Calcium Phosphates; Cell Adhesion; Cell Survival; Cells, Cultured; Coloring Agents; Crystallography; Dental Cements; Drug Combinations; Fibroblasts; Gingiva; Humans; Materials Testing; Methylmethacrylates; Microscopy, Electron, Scanning; Oxides; Polyvinyls; Retrograde Obturation; Root Canal Filling Materials; Silicates; Spectrometry, X-Ray Emission; Surface Properties; Tantalum; Tetrazolium Salts; Thiazoles; Time Factors; Zinc Oxide; Zinc Oxide-Eugenol Cement; Zirconium | 2011 |
Hypoxia promotes mineralization of human dental pulp cells.
Topics: Adolescent; Adult; Anthraquinones; Calcification, Physiologic; Cell Count; Cell Hypoxia; Cell Survival; Cells, Cultured; Coloring Agents; Dental Pulp; Dentin, Secondary; Extracellular Matrix Proteins; Humans; Integrin-Binding Sialoprotein; Osteocalcin; Phosphoproteins; Real-Time Polymerase Chain Reaction; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Young Adult | 2011 |
Effects of a novel hydration accelerant on the biological and mechanical properties of white mineral trioxide aggregate.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Anti-Bacterial Agents; Biocompatible Materials; Calcium; Calcium Compounds; Cell Survival; Coloring Agents; Drug Combinations; Gluconates; Hydrogen-Ion Concentration; Materials Testing; Mice; Microscopy, Electron, Scanning; Osteoblasts; Oxides; Root Canal Filling Materials; Silicates; Streptococcus mutans; Stress, Mechanical; Temperature; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2011 |
Effects of paraoxon on neuronal and lymphocytic cholinergic systems.
Topics: Acetylcholinesterase; Blotting, Western; Cell Line; Cell Survival; Cholinesterase Inhibitors; Coloring Agents; Genes, fos; Humans; Indicators and Reagents; Lymphocytes; Muscarinic Agonists; Neurons; Paraoxon; Parasympathetic Nervous System; Real-Time Polymerase Chain Reaction; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Tetrazolium Salts; Thiazoles | 2011 |
Protective effect of the glial cell line-derived neurotrophic factor (GDNF) on human mesencephalic neuron-derived cells against neurotoxicity induced by paraquat.
Topics: Analysis of Variance; Bucladesine; Cell Differentiation; Cell Line; Cell Survival; Coloring Agents; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Mesencephalon; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Paraquat; Tetrazolium Salts; Thiazoles | 2011 |
Anthocyanins isolated from the purple-fleshed sweet potato attenuate the proliferation of hepatic stellate cells by blocking the PDGF receptor.
Topics: Actins; Animals; Anthocyanins; Blotting, Western; Cell Proliferation; Cell Survival; Coloring Agents; Extracellular Signal-Regulated MAP Kinases; Hepatic Stellate Cells; Ipomoea batatas; L-Lactate Dehydrogenase; Oncogene Protein v-akt; Platelet-Derived Growth Factor; Rats; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
Mitochondria protection of baicalein against oxidative damage via induction of manganese superoxide dismutase.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Fractionation; Cell Survival; Cell-Free System; Coloring Agents; Cricetinae; DNA Fragmentation; Electrophoretic Mobility Shift Assay; Flavanones; Hydroxyl Radical; Indicators and Reagents; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 2011 |
In Salvia miltiorrhiza, phenolic acids possess protective properties against amyloid β-induced cytotoxicity, and tanshinones act as acetylcholinesterase inhibitors.
Topics: Abietanes; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzofurans; Calcium; Cell Survival; Cholinesterase Inhibitors; Hydroxybenzoates; L-Lactate Dehydrogenase; Male; Neuroprotective Agents; PC12 Cells; Phosphatidylinositols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Tetrazolium Salts; Thiazoles | 2011 |
[Effect of decontaminating solutions on titanium surface: an in vitro study of human epithelial cell culture].
Topics: Anti-Infective Agents, Local; Cell Proliferation; Cells, Cultured; Chlorhexidine; Citric Acid; Coloring Agents; Decontamination; Disinfectants; Epithelial Cells; Gels; Humans; Hydrogen Peroxide; Indicators and Reagents; Microscopy, Atomic Force; Photoelectron Spectroscopy; Quinolines; Solutions; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2011 |
The expression and significance of MRP1, LRP, TOPOIIβ, and BCL2 in tongue squamous cell carcinoma.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Shape; Cisplatin; Coloring Agents; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Antibody Technique; Humans; Lymphatic Metastasis; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Grading; Neoplasm Staging; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Tongue; Tongue Neoplasms; Vault Ribonucleoprotein Particles | 2012 |
Combination of docetaxel and vandetanib in docetaxel-sensitive or resistant PC3 cell line.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Male; Piperidines; Prostatic Neoplasms, Castration-Resistant; Quinazolines; Taxoids; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Limitation of the MTT and XTT assays for measuring cell viability due to superoxide formation induced by nano-scale TiO2.
Topics: Animals; Cell Survival; CHO Cells; Coloring Agents; Cricetinae; Cricetulus; Nanoparticles; Superoxides; Tetrazolium Salts; Thiazoles; Titanium; Toxicity Tests | 2011 |
Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters.
Topics: Animals; ATP-Binding Cassette Transporters; Biological Transport; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Multiple; Flow Cytometry; Fluorescent Dyes; Humans; Substrate Specificity; Tetrazolium Salts; Thiazoles | 2011 |
Antidepressant-like effect of hyperoside isolated from Apocynum venetum leaves: possible cellular mechanisms.
Topics: Animals; Antidepressive Agents; Apocynum; Brain-Derived Neurotrophic Factor; Calcium; Cell Survival; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cytoprotection; Fura-2; L-Lactate Dehydrogenase; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Plant Leaves; Quercetin; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2012 |
Anti-Müllerian hormone inhibits growth of AMH type II receptor-positive human ovarian granulosa cell tumor cells by activating apoptosis.
Topics: Analysis of Variance; Animals; Anti-Mullerian Hormone; Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; DNA Primers; Female; Granulosa Cell Tumor; Humans; Immunohistochemistry; Mice; Ovarian Neoplasms; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Signal Transduction; Tetrazolium Salts; Thiazoles | 2011 |
Lipid nanoemulsions loaded with doxorubicin-oleic acid ionic complex: characterization, in vitro and in vivo studies.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Doxorubicin; Drug Carriers; Drug Compounding; Electrochemistry; Emulsions; Flow Cytometry; Humans; Male; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles; Octanols; Oleic Acid; Particle Size; Solubility; Tetrazolium Salts; Thiazoles; Tissue Distribution; Water | 2011 |
Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-α.
Topics: Animals; Benzhydryl Compounds; Blotting, Western; Caspase 3; Cell Line; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Cyclic GMP-Dependent Protein Kinases; DNA Primers; Dose-Response Relationship, Drug; ErbB Receptors; Estrogen Receptor alpha; Luciferases; Male; Mice; Oligodeoxyribonucleotides, Antisense; Phenols; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Receptors, G-Protein-Coupled; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Spermatogonia; Tetrazolium Salts; Thiazoles | 2011 |
Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses.
Topics: Aged; Analysis of Variance; Animals; Cells, Cultured; Dendrites; Disks Large Homolog 4 Protein; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Female; Frontotemporal Dementia; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Humans; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Luminescent Proteins; Male; Membrane Proteins; Microscopy, Electron, Transmission; Mutation; Neurons; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, AMPA; RNA, Small Interfering; Synapses; Synaptic Vesicles; Synaptophysin; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Aerosol deposition of hydroxyapatite and 4-hexylresorcinol coatings on titanium alloys for dental implants.
Topics: Aerosols; Aggregatibacter actinomycetemcomitans; Alkaline Phosphatase; Animals; Anti-Infective Agents, Local; Cell Adhesion; Cell Line, Tumor; Coated Materials, Biocompatible; Coloring Agents; Dental Alloys; Dental Implants; Durapatite; Equipment Contamination; Hexanes; Hexylresorcinol; Materials Testing; Microscopy, Electron, Scanning; Osseointegration; Osteoblasts; Osteocalcin; Osteogenesis; Porphyromonas gingivalis; Prevotella intermedia; Rabbits; Resorcinols; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tibia; Titanium; Torque; X-Ray Diffraction | 2011 |
Quercetin both partially attenuates hydrogen peroxide-induced toxicity and decreases viability of rat glial cells.
Topics: Animals; Antioxidants; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Hydrogen Peroxide; Models, Biological; Neuroglia; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Nickel nanowires induced and reactive oxygen species mediated apoptosis in human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Analysis of Variance; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Fluorescent Dyes; Humans; Microscopy, Phase-Contrast; Nanotechnology; Nanowires; Nickel; Pancreatic Neoplasms; Particle Size; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2011 |
Arecoline induced cell cycle arrest, apoptosis, and cytotoxicity to human endothelial cells.
Topics: Apoptosis; Arecoline; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Cholinergic Agonists; Coloring Agents; DNA; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; G1 Phase; Humans; Interphase; Propidium; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
The nonsteroidal anti-inflammatory drug celecoxib suppresses the growth and induces apoptosis of human glioblastoma cells via the NF-κB pathway.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Brain Neoplasms; Celecoxib; Cell Line, Tumor; Cell Nucleus; Cell Survival; Colony-Forming Units Assay; Coloring Agents; Cyclooxygenase 2 Inhibitors; Cytosol; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Fluorescent Antibody Technique; Glioblastoma; Humans; I-kappa B Proteins; In Situ Nick-End Labeling; NF-kappa B; Protein Transport; Pyrazoles; Signal Transduction; Sulfonamides; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Reversal effects of traditional Chinese herbs on multidrug resistance in cancer cells.
Topics: Acetates; Cassia; Cell Line, Tumor; Chrysanthemum; Curcuma; Doxorubicin; Drug Resistance, Multiple; Drugs, Chinese Herbal; Humans; Ligusticum; Medicine, Chinese Traditional; Methylene Chloride; Plant Extracts; Plants, Medicinal; Salvia; Tetrazolium Salts; Thiazoles | 2011 |
A study of the mechanism of in vitro cytotoxicity of metal oxide nanoparticles using catfish primary hepatocytes and human HepG2 cells.
Topics: Animals; Catfishes; Cell Line; Environmental Health; Flow Cytometry; Hepatocytes; Humans; Metals, Heavy; Nanoparticles; Oxides; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2011 |
Octyl and dodecyl gallates induce oxidative stress and apoptosis in a melanoma cell line.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Catalase; Cell Line, Tumor; Coloring Agents; DNA; fas Receptor; Gallic Acid; L-Lactate Dehydrogenase; Melanoma; Membrane Potential, Mitochondrial; Mice; Neutral Red; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2011 |
Nicotine reduces VEGF-secretion and phagocytotic activity in porcine RPE.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Phagocytosis; Retinal Pigment Epithelium; Swine; Tetrazolium Salts; Thiazoles; Trypan Blue; Vascular Endothelial Growth Factor A | 2012 |
Photodynamic therapy (PDT) - Initiation of apoptosis via activation of stress-activated p38 MAPK and JNK signal pathway in H460 cell lines.
Topics: Aminolevulinic Acid; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Coloring Agents; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Photochemotherapy; Photosensitizing Agents; Prodrugs; Protoporphyrins; Signal Transduction; Tetrazolium Salts; Thiazoles; Up-Regulation | 2011 |
Cytocompatibility of new bioceramic-based materials on human fibroblast cells (MRC-5).
Topics: Biocompatible Materials; Calcium Compounds; Calcium Hydroxide; Calcium Phosphates; Cell Line; Cell Proliferation; Cell Survival; Ceramics; Coloring Agents; Culture Media; Durapatite; Fibroblasts; Humans; Humidity; Hydroxyapatites; Nanocomposites; Root Canal Filling Materials; Silicates; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
C5a contributes to intraocular inflammation by affecting retinal pigment epithelial cells and immune cells.
Topics: Apoptosis; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Complement C5a; Cytokines; Electrophoresis, Polyacrylamide Gel; Eye; Eye Diseases; Gene Expression; Humans; Immunologic Factors; Inflammation; Leukocytes, Mononuclear; Pigment Epithelium of Eye; Real-Time Polymerase Chain Reaction; Receptor, Anaphylatoxin C5a; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta2; Tumor Necrosis Factor-alpha | 2011 |
Sunitinib induces apoptosis in pheochromocytoma tumor cells by inhibiting VEGFR2/Akt/mTOR/S6K1 pathways through modulation of Bcl-2 and BAD.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Coloring Agents; In Situ Nick-End Labeling; Indicators and Reagents; Indoles; Microarray Analysis; Oncogene Protein v-akt; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Rats; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Signal Transduction; Sunitinib; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Metallic ions released from stainless steel, nickel-free, and titanium orthodontic alloys: toxicity and DNA damage.
Topics: Cell Line; Cell Survival; Chromium Alloys; Comet Assay; Culture Media; Dental Alloys; DNA Damage; Fibroblasts; Humans; Ions; Mass Spectrometry; Metals; Orthodontic Brackets; Stainless Steel; Tetrazolium Salts; Thiazoles; Titanium | 2011 |
Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Annexin A5; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Antibody Technique; Humans; Mitochondria; Motor Neurons; Mutation; Neuroprotective Agents; Niacinamide; Propidium; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tetrazolium Salts; Thiazoles; Up-Regulation | 2011 |
Overexpression of interleukin-6 and -8, cell growth inhibition and morphological changes in 2-hydroxyethyl methacrylate-treated human dental pulp mesenchymal stem cells.
Topics: Adolescent; Cell Culture Techniques; Cell Proliferation; Cell Shape; Cell Survival; Coloring Agents; Cytoplasmic Granules; Dental Materials; Dental Pulp; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Methacrylates; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2012 |
Effect of heat stress on the expression levels of receptor activator of NF-κB ligand and osteoprotegerin in human periodontal ligament cells.
Topics: Cell Survival; Cells, Cultured; Coloring Agents; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Heat-Shock Response; Humans; Osteoprotegerin; Periodontal Ligament; RANK Ligand; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation | 2012 |
Anti-inflammatory cembranoids from the Formosan soft coral Sinularia discrepans.
Topics: Animals; Anthozoa; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cnidaria; Cyclooxygenase 2; Diterpenes; Drug Screening Assays, Antitumor; Humans; Macrophages; Molecular Structure; Nitric Oxide Synthase Type II; Tetrazolium Salts; Thiazoles | 2011 |
1-oxoeudesm-11(13)-ene-12,8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Fractionation; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Female; Hepatocytes; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Sesquiterpenes, Eudesmane; Tetrazolium Salts; Thiazoles | 2011 |
Regulation of histone acetylation by NDRG2 in glioma cells.
Topics: Acetylation; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioma; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Proteins | 2012 |
Immunosuppressive proteins isolated from spiral and coccoid cytoplasmic solutions of Helicobacter pylori.
Topics: Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Proteins; Cell Proliferation; Cell Survival; Chromatography; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Helicobacter Infections; Helicobacter pylori; Humans; Immune System; Immunosuppressive Agents; Jurkat Cells; Tetrazolium Salts; Thiazoles | 2011 |
Beta amyloid effects on expression of multidrug efflux transporters in brain endothelial cells.
Topics: Amyloid beta-Peptides; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; beta Catenin; Biological Transport; Brain; Cell Line, Transformed; Endothelial Cells; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Rhodamine 123; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Wnt Proteins | 2011 |
A new FRET nanoprobe for trypsin using a bridged β-cyclodextrin dimer-dye complex and its biological imaging applications.
Topics: beta-Cyclodextrins; Cell Line, Tumor; Coloring Agents; Dimerization; Fluorescence Resonance Energy Transfer; Gold; Humans; Mercaptoethylamines; Metal Nanoparticles; Microscopy, Confocal; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Trypsin | 2011 |
Gene transport and expression by arginine-rich cell-penetrating peptides in Paramecium.
Topics: Arginine; Biological Transport; Carrier Proteins; Cell Membrane; Cell Physiological Phenomena; Cell-Penetrating Peptides; DNA, Protozoan; Genes, Protozoan; Green Fluorescent Proteins; Microscopy, Fluorescence; Paramecium caudatum; Plasmids; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Endocrine effects of methoxylated brominated diphenyl ethers in three in vitro models.
Topics: Analysis of Variance; Androgen Receptor Antagonists; Animals; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Endocrine Disruptors; Genes, Reporter; Halogenated Diphenyl Ethers; Humans; In Vitro Techniques; Inhibitory Concentration 50; Luciferases; Mice; Molecular Structure; Plasmids; Rats; Receptors, Estrogen; Receptors, Thyroid Hormone; Tetrazolium Salts; Thiazoles | 2011 |
A comparison of BGM and LLC-PK1 cells for the evaluation of nephrotoxicity.
Topics: Animals; Apoptosis; Cell Line; Chlorocebus aethiops; Gentamicins; Kidney; Mitochondria; Neutral Red; Sus scrofa; Tetrazolium Salts; Thiazoles | 2012 |
Small interfering RNA against the 2C genomic region of coxsackievirus B3 exerts potential antiviral effects in permissive HeLa cells.
Topics: Antiviral Agents; Biological Products; Carrier Proteins; Cell Survival; Cytopathogenic Effect, Viral; Enterovirus B, Human; HeLa Cells; Humans; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Viral Nonstructural Proteins; Virus Replication | 2012 |
Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
Topics: Adolescent; Adult; Aged; Butadienes; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Corneal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Confocal; Middle Aged; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Threonine; Tissue Donors; Transfection; Young Adult | 2011 |
Areca nut extracts suppress the differentiation and functionality of human monocyte-derived dendritic cells.
Topics: Areca; B7-1 Antigen; B7-2 Antigen; CD11c Antigen; CD40 Antigens; Cell Culture Techniques; Cell Differentiation; Coloring Agents; Dendritic Cells; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-DR Antigens; Humans; Interleukin-12; Interleukin-4; Lipopolysaccharides; Monocytes; Nuts; Phenotype; Plant Extracts; Tetrazolium Salts; Thiazoles | 2012 |
The first BAFF gene cloned from the cartilaginous fish.
Topics: Amino Acid Sequence; Animals; B-Cell Activating Factor; Base Sequence; Blotting, Western; Cluster Analysis; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Models, Molecular; Molecular Sequence Data; Nucleic Acid Amplification Techniques; Open Reading Frames; Phylogeny; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sharks; Species Specificity; Spleen; Tetrazolium Salts; Thiazoles | 2011 |
Seasonal changes in activities of human neutrophils in vitro.
Topics: Anti-Infective Agents; CD11b Antigen; CD18 Antigens; Cell Adhesion; Coloring Agents; Escherichia coli; Humans; Immune System; Male; Neutrophils; Reactive Oxygen Species; Retrospective Studies; Seasons; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.
Topics: 3T3 Cells; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Calcium; Cardiotonic Agents; Cell Culture Techniques; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Losartan; Male; Mice; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptides; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Tetrazolium Salts; Thiazoles; Type C Phospholipases; Vasoconstrictor Agents | 2011 |
Aglycon of rhizochalin from the Rhizochalina incrustata induces apoptosis via activation of AMP-activated protein kinase in HT-29 colon cancer cells.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; DNA Fragmentation; Drug Evaluation, Preclinical; Extracellular Signal-Regulated MAP Kinases; Fatty Alcohols; Glycosphingolipids; HT29 Cells; Humans; Mice; Mitogen-Activated Protein Kinases; Molecular Targeted Therapy; Oceans and Seas; Phosphorylation; Phytotherapy; Plant Preparations; Poly(ADP-ribose) Polymerases; Porifera; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
Propolis protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity in rat hepatocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cell Separation; Cells, Cultured; Coloring Agents; Deoxyguanosine; DNA Damage; Hepatocytes; L-Lactate Dehydrogenase; Male; Micronucleus Tests; Polychlorinated Dibenzodioxins; Propolis; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 2012 |
Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway.
Topics: Animals; Calcium; Caspase 3; Cell Death; CHO Cells; Cricetinae; Germanium; Membrane Potential, Mitochondrial; Metal Nanoparticles; Necrosis; Reactive Oxygen Species; Signal Transduction; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2011 |
Comparison of in vitro biocompatibility of NanoBone(®) and BioOss(®) for human osteoblasts.
Topics: Animals; Biocompatible Materials; Bone Matrix; Bone Substitutes; Bromodeoxyuridine; Cattle; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Drug Combinations; Durapatite; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Materials Testing; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Minerals; Osteoblasts; Silicon Dioxide; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2011 |
In vitro & in vivo estrogenic activity of glycoside fractions of Solanum nigrum fruit.
Topics: Analysis of Variance; Animals; Cell Survival; Chemical Fractionation; Dose-Response Relationship, Drug; Durapatite; Estrogens; Female; Fruit; Glycosides; Histological Techniques; India; Methanol; Mice; Microscopy, Fluorescence; Plant Extracts; Solanum nigrum; Tetrazolium Salts; Thiazoles; Tritium | 2011 |
A role for c-Myc in regulating anti-mycobacterial responses.
Topics: Analysis of Variance; Antibodies, Monoclonal; Blotting, Western; Cell Line; Colony Count, Microbial; Cytoplasm; DNA Primers; Humans; Immunity, Innate; Immunohistochemistry; Interleukin-1 Receptor-Associated Kinases; Leukocytes, Mononuclear; MAP Kinase Signaling System; Mycobacterium; Mycobacterium Infections; Plasmids; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Species Specificity; Tetrazolium Salts; Thiazoles | 2011 |
Periodontal ligament fibroblast response to root perforations restored with different materials: a laboratory study.
Topics: Aluminum Compounds; Boron Compounds; Calcium Compounds; Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Survival; Collagen Type I; Coloring Agents; Compomers; Core Binding Factor Alpha 1 Subunit; Dental Amalgam; Drug Combinations; Fibroblasts; Humans; Materials Testing; Methacrylates; Methylmethacrylates; Microscopy, Confocal; Oxides; Periodontal Ligament; Real-Time Polymerase Chain Reaction; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Tooth Root; Zinc Oxide-Eugenol Cement | 2012 |
Activation of erythropoietin-producing hepatocellular receptor A2 attenuates cell adhesion of human fallopian tube epithelial cells via focal adhesion kinase dephosphorylation.
Topics: Adult; Cell Adhesion; Cells, Cultured; Ephrin-A1; Epithelial Cells; Fallopian Tubes; Female; Focal Adhesion Kinase 1; Humans; Immunoglobulin Fc Fragments; Middle Aged; Phosphorylation; Receptor, EphA2; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles | 2012 |
Real-time monitoring of extracellular matrix-mediated PC12 cell attachment and proliferation using an electronic biosensing device.
Topics: Animals; Biosensing Techniques; Cell Adhesion; Cell Proliferation; Electric Impedance; Extracellular Matrix; PC12 Cells; Rats; Staining and Labeling; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Mutagenic and morphologic impacts of 1.8GHz radiofrequency radiation on human peripheral blood lymphocytes (hPBLs) and possible protective role of pre-treatment with Ginkgo biloba (EGb 761).
Topics: Cell Proliferation; Cell Survival; Ginkgo biloba; Humans; Lymphocytes; Microscopy, Electron, Transmission; Microwaves; Plant Extracts; Radiation Tolerance; Radiation-Protective Agents; Sister Chromatid Exchange; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Glutaminase dysregulation in HIV-1-infected human microglia mediates neurotoxicity: relevant to HIV-1-associated neurocognitive disorders.
Topics: Analysis of Variance; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain; Caspase 3; Cells, Cultured; Chromatography, High Pressure Liquid; Disintegrins; Dizocilpine Maleate; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation, Viral; Glutamic Acid; Glutaminase; Glutamine; HIV Infections; HIV-1; Humans; Microglia; Microtubule-Associated Proteins; Receptors, Cell Surface; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Influence of the activation mode of a self-etch resin-based luting cement upon the metabolism of odontoblast-like cells.
Topics: Alkaline Phosphatase; Apatites; Cell Line; Cell Shape; Cell Survival; Coloring Agents; Culture Media, Conditioned; Dental Porcelain; Dental Pulp; Dentin-Bonding Agents; Humans; Light-Curing of Dental Adhesives; Lithium Compounds; Microscopy, Electron, Scanning; Odontoblasts; Proteins; Resin Cements; Self-Curing of Dental Resins; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2011 |
Ketamine and propofol in combination induce neuroapoptosis and down-regulate the expression of N-methyl-D-aspartate glutamate receptor NR2B subunit in rat forebrain culture.
Topics: Anesthetics, Intravenous; Animals; Apoptosis; Blotting, Western; Caspase 3; DNA, Complementary; Drug Synergism; Excitatory Amino Acid Antagonists; Ketamine; Neurons; Organ Culture Techniques; Propofol; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles | 2011 |
Inhibitory effect of YQHYRJ recipe on osteoblast differentiation induced by BMP-2 in fibroblasts from posterior longitudinal ligament of mice.
Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Separation; Chromatography, High Pressure Liquid; Collagen Type I; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Drugs, Chinese Herbal; Fibroblasts; Immunohistochemistry; In Vitro Techniques; Longitudinal Ligaments; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Ossification of Posterior Longitudinal Ligament; Osteoblasts; Osteocalcin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad1 Protein; Smad5 Protein; Tetrazolium Salts; Thiazoles | 2011 |
Ibrolipim attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
Topics: Benzamides; Blotting, Western; Cell Survival; Cells, Cultured; Coloring Agents; Endothelial Cells; Endothelin-1; Female; Gene Expression; Glucose; Humans; Hypolipidemic Agents; Indicators and Reagents; Oncogene Protein v-akt; Organophosphorus Compounds; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Umbilical Veins; von Willebrand Factor | 2011 |
Activity of ozonated water and ozone against Staphylococcus aureus and Pseudomonas aeruginosa biofilms.
Topics: Biofilms; Oxygen; Ozone; Pseudomonas aeruginosa; Staphylococcus aureus; Survival Analysis; Tetrazolium Salts; Thiazoles; Water | 2011 |
Gene expression signatures and ex vivo drug sensitivity profiles in children with acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Biopsy; Bone Marrow Cells; Child; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Genes, Neoplasm; Humans; Male; Oligonucleotide Array Sequence Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tetrazolium Salts; Thiazoles | 2012 |
A novel mechanism of increased infections in contact lens wearers.
Topics: Blotting, Western; CA-125 Antigen; Cell Line; Contact Lens Solutions; Epithelium, Corneal; Gene Expression Regulation; Humans; Membrane Proteins; Metalloproteases; Phagocytosis; Pseudomonas aeruginosa; Real-Time Polymerase Chain Reaction; RNA, Messenger; Rose Bengal; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2011 |
Protective efficacy of Anopheles minimus CYP6P7 and CYP6AA3 against cytotoxicity of pyrethroid insecticides in Spodoptera frugiperda (Sf9) insect cells.
Topics: Animals; Anopheles; Cell Line; Cell Survival; Cloning, Molecular; Cytochrome P-450 Enzyme System; Cytological Techniques; Gene Expression; Insecticides; Pyrethrins; Spodoptera; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2011 |
Immunocytochemical studies on the effect of 405-nm low-power laser irradiation on human-derived A-172 glioblastoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Glioblastoma; Humans; Immunohistochemistry; Low-Level Light Therapy; Microscopy, Fluorescence; Necrosis; Tetrazolium Salts; Thiazoles | 2012 |
Implantable polyimide cable for multichannel high-data-rate neural recording microsystems.
Topics: Absorption; Cell Line, Tumor; Cell Survival; Equipment Design; Humans; Implants, Experimental; Materials Testing; Neural Prostheses; Resins, Synthetic; Surface Properties; Tetrazolium Salts; Thiazoles; Water | 2012 |
Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds.
Topics: Biocompatible Materials; Calcium Phosphates; Cell Adhesion; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Chemical Phenomena; Coloring Agents; Compressive Strength; Computer-Aided Design; Hot Temperature; Humans; Imaging, Three-Dimensional; Materials Testing; Mechanical Phenomena; Microscopy, Electron, Scanning; Osteoblasts; Porosity; Silicon Dioxide; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; X-Ray Diffraction; Zinc Oxide | 2012 |
Growth inhibition of malignant glioblastoma by DING protein.
Topics: Animals; CDC2 Protein Kinase; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cyclin B; Cyclin E; Cyclin-Dependent Kinases; DNA-Binding Proteins; E2F Transcription Factors; Endopeptidase K; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; Green Fluorescent Proteins; Humans; Hypericum; Mice; Plant Preparations; Polycomb Repressive Complex 1; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Ubiquitin-Protein Ligases | 2012 |
Histone deacetylase inhibition by sodium valproate regulates polarization of macrophage subsets.
Topics: Animals; Cell Line; Cell Polarity; DNA Primers; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Expression Regulation; Histone Deacetylase Inhibitors; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Valproic Acid | 2012 |
High transfection efficiency of porcine peripheral blood T cells via nucleofection.
Topics: Animals; Cell Survival; DNA; Electroporation; Flow Cytometry; Green Fluorescent Proteins; Real-Time Polymerase Chain Reaction; RNA, Messenger; Swine; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Hemin-coupled iron(III)-hydroxide nanoparticles show increased uptake in Caco-2 cells.
Topics: Caco-2 Cells; Colorimetry; Coloring Agents; Culture Media; Ferric Compounds; Ferrozine; Hemin; Humans; Iron Chelating Agents; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Scattering, Radiation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2011 |
Monascus purpureus-fermented rice inhibits tumor necrosis factor-α-induced upregulation of matrix metalloproteinase 2 and 9 in human aortic smooth muscle cells.
Topics: Aorta, Thoracic; Atherosclerosis; Basement Membrane; Biological Products; Blotting, Western; Cells, Cultured; Coloring Agents; Electrophoretic Mobility Shift Assay; Extracellular Matrix; Graft Occlusion, Vascular; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Smooth Muscle; Polymerase Chain Reaction; Reactive Oxygen Species; RNA; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
In vitro evaluation of cytotoxicity of permanent prosthetic materials.
Topics: Aluminum Silicates; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Chromium Alloys; Colorimetry; Coloring Agents; Dental Materials; Dental Porcelain; Dental Prosthesis; Fibroblasts; Gingiva; Gold Alloys; Humans; Materials Testing; Potassium Compounds; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2011 |
Optimization of macroporous 3-D silk fibroin scaffolds by salt-leaching procedure in organic solvent-free conditions.
Topics: Animals; Biotechnology; Bombyx; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Fibroins; Humans; Microscopy, Electron, Scanning; Models, Chemical; Organic Chemicals; Porosity; Salts; Solvents; Tetrazolium Salts; Thiazoles; Tissue Engineering; X-Ray Diffraction | 2012 |
A new furostanol saponin from Asparagus cochinchinensis.
Topics: Antineoplastic Agents, Phytogenic; Asparagus Plant; Cell Line, Tumor; Chromatography, Gas; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Roots; Saponins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Steroids; Tetrazolium Salts; Thiazoles | 2011 |
Anti-inflammatory activity on LPS-stimulated dendritic cells of lupanetype triterpenoids from the leaves of Acanthopanax koreanum.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Cells, Cultured; Cytokines; Dendritic Cells; Eleutherococcus; Interleukin-12; Interleukin-6; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Plant Extracts; Plant Leaves; Tetrazolium Salts; Thiazoles; Triterpenes; Tumor Necrosis Factor-alpha | 2011 |
Effect of pluronic P123 and F127 block copolymer on P-glycoprotein transport and CYP3A metabolism.
Topics: Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Cytochrome P-450 CYP3A; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Microsomes; Midazolam; Poloxalene; Poloxamer; Rats; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2011 |
Three-dimensional culture of mouse bone marrow cells on stroma formed within a porous scaffold: influence of scaffold shape and cryopreservation of the stromal layer on expansion of haematopoietic progenitor cells.
Topics: Animals; Bone Marrow Cells; Cell Count; Cell Culture Techniques; Cell Separation; Cells, Cultured; Coloring Agents; Cryopreservation; Flow Cytometry; Hematopoietic Stem Cells; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Porosity; Stem Cells; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2013 |
The cytotoxic effects of three different bisphosphonates in-vitro on human gingival fibroblasts, osteoblasts and osteogenic sarcoma cells.
Topics: Alendronate; Alkaline Phosphatase; Bone Density Conservation Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen Type I; Coloring Agents; Diphosphates; Diphosphonates; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Follow-Up Studies; Gingiva; Humans; Imidazoles; Osteoblasts; Osteocalcin; Osteosarcoma; Pamidronate; Tetrazolium Salts; Thiazoles; Zoledronic Acid | 2012 |
A combined chitosan/nano-size hydroxyapatite system for the controlled release of icariin.
Topics: Alkaline Phosphatase; Animals; Bone Marrow Cells; Chitosan; Drug Carriers; Drug Delivery Systems; Durapatite; Flavonoids; Hydrolysis; Kinetics; Mice; Mice, Inbred BALB C; Nanoparticles; Nanotechnology; Porosity; Stress, Mechanical; Stromal Cells; Technology, Pharmaceutical; Tetrazolium Salts; Thiazoles | 2012 |
Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells.
Topics: Animals; Cell Line; Cell Survival; Coloring Agents; Comet Assay; Culture Media; Cytokines; Cytotoxins; DNA Damage; DNA Glycosylases; Germ Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagens; Nanoparticles; Particle Size; Reproduction; Silver; Testis; Tetrazolium Salts; Thiazoles; Titanium | 2012 |
NSC 74859-mediated inhibition of STAT3 enhances the anti-proliferative activity of cetuximab in hepatocellular carcinoma.
Topics: Aminosalicylic Acids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cetuximab; Drug Screening Assays, Antitumor; Drug Synergism; Hepatocytes; Humans; Liver Neoplasms; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
Ammonia-containing dimethyl sulfoxide: an improved solvent for the dissolution of formazan crystals in the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay.
Topics: Ammonia; Animals; Cell Survival; Colorimetry; Coloring Agents; Dimethyl Sulfoxide; Escherichia coli; Formazans; Solubility; Solvents; Tetrazolium Salts; Thiazoles | 2012 |
A new approach with less damage: intranasal delivery of tetracycline-inducible replication-defective herpes simplex virus type-1 vector to brain.
Topics: Analysis of Variance; Animals; beta-Galactosidase; Brain; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Viral; Genetic Vectors; Herpesvirus 1, Human; In Situ Nick-End Labeling; Male; Microscopy, Electron, Transmission; Neurons; Rats; Rats, Sprague-Dawley; Tetracycline; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2012 |
Synthesis, anticancer activity and apoptosis inducing ability of bisindole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Topics: Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Cycle; Cell Line, Tumor; Cell Separation; Chemistry, Pharmaceutical; Diet; Drug Design; Flow Cytometry; Histone Deacetylase Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Models, Chemical; Poly(ADP-ribose) Polymerases; Pyrroles; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Altholactone induces apoptotic cell death in human colorectal cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase Inhibitors; Caspases, Initiator; Cell Death; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Enzyme Activation; Fibroblasts; Furans; Goniothalamus; HCT116 Cells; HT29 Cells; Humans; Oxidative Stress; Propidium; Pyrones; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
Anti-apoptotic effect of HCV core gene of genotype 3a in Huh-7 cell line.
Topics: Apoptosis; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Gene Expression Profiling; Genotype; Hepacivirus; Hepatocytes; Humans; Oncogene Protein v-akt; Pakistan; Phosphorylation; Protein Processing, Post-Translational; Real-Time Polymerase Chain Reaction; Staining and Labeling; Tetrazolium Salts; Thiazoles; Viral Core Proteins | 2011 |
Annonacin in Asimina triloba fruit: implication for neurotoxicity.
Topics: Animals; Animals, Newborn; Asimina; Cell Count; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Fruit; Furans; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2012 |
Control of cell nucleus shapes via micropillar patterns.
Topics: Animals; Animals, Newborn; Bone Marrow Cells; Cell Differentiation; Cell Nucleus; Cell Nucleus Shape; Cell Proliferation; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Stromal Cells; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Synthesis and in vitro and in vivo anticancer activity of novel phenylmethylene bis-isoxazolo[4,5-b]azepines.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Line, Tumor; Chemistry, Pharmaceutical; Cisplatin; Drug Design; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Inhibitory Concentration 50; Isoxazoles; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Mice; Models, Chemical; Neoplasms; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles | 2012 |
Effects of polysaccharides from Morchella conica on nitric oxide production in lipopolysaccharide-treated macrophages.
Topics: Animals; Ascomycota; Cell Line; Heme Oxygenase-1; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Polysaccharides; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
Effects of four types of hydroxyapatite nanoparticles with different nanocrystal morphologies and sizes on apoptosis in rat osteoblasts.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Crystallization; Cytochromes c; Dose-Response Relationship, Drug; Durapatite; Nanoparticles; Osteoblasts; Oxidative Stress; Particle Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2012 |
Biosynthesis of gold nanoparticles using chloroplasts.
Topics: Biotechnology; Cell Line, Tumor; Cell Survival; Chloroplasts; Gold; Green Chemistry Technology; Humans; Metal Nanoparticles; Particle Size; Rhodamines; Tetrazolium Salts; Thiazoles; Trifolium | 2011 |
Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Baculoviridae; Cell Line, Tumor; Colonic Neoplasms; Cross-Linking Reagents; DNA Mismatch Repair; DNA-Binding Proteins; Fluorouracil; Humans; Microsatellite Repeats; Oligonucleotides; Recombinant Proteins; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2011 |
Crosstalk between JNK and SUMO signaling pathways: deSUMOylation is protective against H2O2-induced cell injury.
Topics: Cell Death; Cell Line, Tumor; Cell Survival; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Immunohistochemistry; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Oxidative Stress; Plasmids; Proto-Oncogene Proteins c-jun; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Nanoformulation of siRNA silencing Bcl-2 gene and its implication in cancer therapy.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Coloring Agents; Drug Compounding; Drug Delivery Systems; Electrochemistry; Female; Fluorescent Antibody Technique; Gene Silencing; Genes, bcl-2; Genetic Therapy; Humans; Lactic Acid; Male; Mice; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reverse Transcriptase Polymerase Chain Reaction; Rhodamines; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
Hypoxic preconditioning enhances survival of human adipose-derived stem cells and conditions endothelial cells in vitro.
Topics: Adipose Tissue; Cell Hypoxia; Cell Shape; Cell Survival; Chromones; Culture Media, Conditioned; Culture Media, Serum-Free; Cytoprotection; Endothelial Cells; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Middle Aged; Morpholines; Neovascularization, Physiologic; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor A | 2012 |
Imidazo [4,5f][1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-κB pathway.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Inhibitory Concentration 50; Lung Neoplasms; Models, Chemical; Necrosis; NF-kappa B; Phenanthrolines; Proto-Oncogene Proteins c-myc; Tetrazolium Salts; Thiazoles | 2012 |
Exposure to dibenzofuran triggers autophagy in lung cells.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Autophagy; Benzofurans; Blotting, Western; Cell Death; Cell Line; Cell Nucleus; Cell Proliferation; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Energy Metabolism; Environmental Pollutants; Humans; L-Lactate Dehydrogenase; Lung; Lysosomes; Membrane Potential, Mitochondrial; Mice; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
HIF-1α is neuroprotective during the early phases of mild hypoxia in rat cortical neurons.
Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 1; Cytochromes c; Dose-Response Relationship, Drug; Free Radical Scavengers; Gene Expression Regulation; Glutathione; Green Fluorescent Proteins; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Membrane Proteins; Metalloporphyrins; Neurons; Oxygen; Phenanthridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA Interference; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Propidium iodide staining method for testing the cytotoxicity of 2,4,6-trichlorophenol and perfluorooctane sulfonate at low concentrations with Vero cells.
Topics: Alkanesulfonic Acids; Animals; Cell Membrane; Cell Proliferation; Cell Survival; Chlorocebus aethiops; Chlorophenols; Coloring Agents; Environmental Pollutants; Fluorocarbons; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Phospholipids; Propidium; Tetrazolium Salts; Thiazoles; Vero Cells | 2011 |
Treatment effects of the multikinase inhibitor sorafenib on hepatoblastoma cell lines and xenografts in NMRI-Foxn1 nu mice.
Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique, Indirect; Forkhead Transcription Factors; Hepatoblastoma; In Situ Nick-End Labeling; Mice; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Sorafenib; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous; Transplants | 2012 |
The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Apoptosis; Aspartic Acid Endopeptidases; Blotting, Western; Brain; Cell Death; Coloring Agents; Fluorescent Antibody Technique; Gene Expression Regulation; In Situ Nick-End Labeling; MicroRNAs; Necrosis; PC12 Cells; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
G0/G1 phase arrest and apoptosis induced by manganese chloride on cultured rat astrocytes and protective effects of riluzole.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Cell Cycle; Cell Cycle Checkpoints; Cell Survival; Cells, Cultured; Chlorides; Coloring Agents; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; L-Lactate Dehydrogenase; Manganese Compounds; Manganese Poisoning; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resting Phase, Cell Cycle; Riluzole; Tetrazolium Salts; Thiazoles | 2011 |
Deoxyactein Isolated from Cimicifuga racemosa protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antifungal Agents; Antimycin A; Calcium; Cardiolipins; Cimicifuga; Coloring Agents; Cyclic AMP Response Element-Binding Protein; Electron Transport Complex IV; Membrane Potential, Mitochondrial; Mice; Mitochondria; Oncogene Protein v-akt; Osteoblasts; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Saponins; Tetrazolium Salts; Thiazoles; Thioredoxin-Disulfide Reductase; Triterpenes; Tyrosine | 2013 |
In Vitro effect of low-level laser therapy on typical oral microbial biofilms.
Topics: Bacteriological Techniques; Biofilms; Candida albicans; Coloring Agents; Dose-Response Relationship, Radiation; Humans; Hyphae; Lasers, Semiconductor; Low-Level Light Therapy; Materials Testing; Microbial Interactions; Microbial Viability; Microscopy, Electron, Scanning; Mouth; Mycology; Radiation Dosage; Streptococcus mutans; Succinate Dehydrogenase; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2011 |
Occurrence of thyroid hormone activities in drinking water from eastern China: contributions of phthalate esters.
Topics: Analysis of Variance; Animals; Cell Line; China; Chlorocebus aethiops; Dibutyl Phthalate; Drinking Water; Endocrine Disruptors; Esters; Humans; In Vitro Techniques; Receptors, Thyroid Hormone; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical; Water Purification | 2012 |
Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Embryo, Mammalian; Gene Expression Regulation, Developmental; Interleukin-18 Receptor alpha Subunit; Interleukin-1beta; Mesencephalon; Nerve Tissue Proteins; Neural Stem Cells; Rats; Receptors, Interleukin-1; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
RNAi mediated silencing of ATPase RNA helicase gene in adult filarial parasite Brugia malayi impairs in vitro microfilaria release and adult parasite viability.
Topics: Adenosine Triphosphatases; Analysis of Variance; Animals; DNA Primers; Electroporation; Female; Gene Knockdown Techniques; Male; Microfilariae; Reverse Transcriptase Polymerase Chain Reaction; RNA Helicases; RNA Interference; RNA, Small Interfering; Spirurida; Tetrazolium Salts; Thiazoles | 2012 |
Prostaglandin E2 receptor 1 activity regulates cell survival following hypoxia in cultured rat cortical neurons.
Topics: Analysis of Variance; Animals; Annexin A5; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclin D1; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Hydrazines; Hypoxia; Neurons; Oxazepines; Oxygen; Rats; Rats, Wistar; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2012 |
Inhibition of human tumor xenograft growth in nude mice by a novel monoclonal anti-HSPG isolated from human liver.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Cell Proliferation; Hep G2 Cells; Heparan Sulfate Proteoglycans; Humans; Immunohistochemistry; Immunotherapy; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Proteoglycans; Tetrazolium Salts; Thiazoles | 2011 |
Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells.
Topics: Acetylcysteine; Apoptosis; Arsenic; Ascorbic Acid; Benzimidazoles; Buthionine Sulfoximine; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Leukocytes, Mononuclear; Models, Chemical; Organic Chemicals; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2011 |
Differential cytotoxic effects of sodium meta-arsenite on human cancer cells, dental papilla stem cells and somatic cells correlate with telomeric properties and gene expression.
Topics: Arsenites; Cell Line, Tumor; Dental Papilla; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Models, Statistical; Sodium Compounds; Stem Cells; Telomerase; Telomere; Tetrazolium Salts; Thiazoles | 2011 |
Neuromelanin enhances the toxicity of α-synuclein in SK-N-SH cells.
Topics: Adult; Aged; alpha-Synuclein; Apoptosis; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Survival; Coloring Agents; Dopaminergic Neurons; Female; Humans; Hydroxyl Radical; In Situ Nick-End Labeling; Iron; Lipid Peroxidation; Male; Melanins; Middle Aged; Oxidative Stress; Risk Factors; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blotting, Western; C-Reactive Protein; Coloring Agents; Complement C1; Enzyme-Linked Immunosorbent Assay; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Mice, Transgenic; PC12 Cells; Presenilin-1; Presenilin-2; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
A PKC-beta inhibitor prompts the HUVECs apoptosis-induced by advanced glycation end products.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-Associated Death Protein; Coloring Agents; Endothelial Cells; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Indoles; Maleimides; Microscopy, Fluorescence; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2011 |
Research on an in vitro cell system for testing the neurotoxicity of kynurenine pathway metabolites.
Topics: Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Survival; Coloring Agents; Fluorescent Antibody Technique; Humans; Hydroxydopamines; Isoquinolines; Kynurenine; Neuroblastoma; Neurotoxins; Quinolinic Acid; Tetrazolium Salts; Thiazoles; Tretinoin | 2011 |
Chlorin-based photodynamic therapy enhances the effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in bladder cancer cells.
Topics: Analysis of Variance; Annexin A5; Apoptosis; Cell Line, Tumor; Flow Cytometry; Humans; L-Lactate Dehydrogenase; Photochemotherapy; Porphyrins; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Urinary Bladder Neoplasms | 2012 |
Disruption of tubulin polymerization and cell proliferation by 1-naphthylarsonic acid.
Topics: Animals; Apoptosis; Arsenicals; Binding Sites; Brain; Cell Proliferation; Fibroblasts; HeLa Cells; Humans; In Situ Nick-End Labeling; Microscopy, Electron, Transmission; Microtubules; Models, Molecular; Polymerization; Protein Binding; Sheep; Tetrazolium Salts; Thiazoles; Tissue Extracts; Tubulin; Tubulin Modulators | 2012 |
Macrophage immunomodulating and antitumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms.
Topics: Agaricus; Animals; Antineoplastic Agents; Biological Products; Cell Line, Tumor; Cell Proliferation; Female; Humans; Immunologic Factors; Immunomodulation; Inflammation Mediators; Macrophages; Male; Mice; Mice, Inbred C57BL; Molecular Weight; Neoplasms; NF-kappa B; Polysaccharides; Tetrazolium Salts; Thiazoles | 2012 |
Soy peptide-induced stem cell proliferation: involvement of ERK and TGF-β1.
Topics: Cell Line; Cell Proliferation; Deoxyuridine; Eukaryotic Initiation Factor-4E; Gene Expression Regulation; Humans; Interleukin-6; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 3; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Soybean Proteins; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2012 |
Influence of recasting different types of dental alloys on gingival fibroblast cytotoxicity.
Topics: Adult; Cell Survival; Cells, Cultured; Chromium; Chromium Alloys; Cobalt; Colorimetry; Coloring Agents; Culture Media, Conditioned; Dental Alloys; Dental Casting Technique; Diffusion; Equipment Reuse; Fibroblasts; Gingiva; Gold; Gold Alloys; Humans; Materials Testing; Microscopy, Electron, Scanning; Nickel; Platinum; Spectrometry, X-Ray Emission; Spectrophotometry, Atomic; Tetrazolium Salts; Thiazoles | 2012 |
Effect of antisense oligodeoxynucleotide targeted against NF-κB/P65 on cell proliferation and tumorigenesis of gastric cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Humans; Mice; Mice, Nude; Oligodeoxyribonucleotides, Antisense; Staining and Labeling; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transcription Factor RelA | 2013 |
The combined influence of surface modification, size distribution, and interaction time on the cytotoxicity of CdTe quantum dots in PANC-1 cells.
Topics: Cadmium Compounds; Carcinoma; Cell Line, Tumor; Cell Survival; Chemistry, Physical; Fluorescent Dyes; Humans; Microscopy, Confocal; Nanotechnology; Pancreatic Neoplasms; Quantum Dots; Surface Properties; Tellurium; Tetrazolium Salts; Thiazoles | 2012 |
Differential effects of LY294002 and wortmannin on inducible nitric oxide synthase expression in glomerular mesangial cells.
Topics: Androstadienes; Animals; Blotting, Western; Cell Line; Chromones; Coloring Agents; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Lipopolysaccharides; Mesangial Cells; Mice; Morpholines; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection; Wortmannin | 2012 |
Pro-apoptotic effects of tepoxalin, a cyclooxygenase/lipoxygenase dual inhibitor, on canine synovial fibroblasts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azure Stains; Benzimidazoles; Benzoquinones; Carbazoles; Cells, Cultured; Colorimetry; Cyclooxygenase Inhibitors; Dogs; Fibroblasts; Lipoxygenase Inhibitors; Meloxicam; Pyrazoles; Synovial Fluid; Tetrazolium Salts; Thiazines; Thiazoles | 2012 |
Mn-doped ZnSe d-dots-based α-methylacyl-CoA racemase probe for human prostate cancer cell imaging.
Topics: Androgens; Biomarkers, Tumor; Cadmium; Cell Line, Tumor; Cell Survival; Humans; Male; Manganese; Prostatic Neoplasms; Quantum Dots; Racemases and Epimerases; Selenium Compounds; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Zinc Compounds | 2012 |
The role of surface implant treatments on the biological behavior of SaOS-2 osteoblast-like cells. An in vitro comparative study.
Topics: Acid Etching, Dental; Alkaline Phosphatase; Aluminum Oxide; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Coloring Agents; Dental Etching; Dental Implants; Dental Materials; Dental Prosthesis Design; Electrochemical Techniques; Electron Probe Microanalysis; Humans; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2013 |
Minocycline protects oligodendroglial precursor cells against injury caused by oxygen-glucose deprivation.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Cells, Cultured; Embryo, Mammalian; Embryonic Stem Cells; Female; Gangliosides; Gene Expression Regulation; Glucose; Hypoxia; Ki-67 Antigen; Minocycline; Myelin Basic Protein; O Antigens; Oligodendroglia; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2012 |
In vitro efficacy of fosfomycin-containing regimens against methicillin-resistant Staphylococcus aureus in biofilms.
Topics: Anti-Bacterial Agents; Biofilms; Drug Interactions; Fosfomycin; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Rifampin; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
Clinical impact of in vitro cellular drug resistance on childhood acute lymphoblastic leukemia in Taiwan.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Recurrence; Sex Factors; Taiwan; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2012 |
DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging.
Topics: Base Sequence; Cell Survival; Fluorescent Dyes; G-Quadruplexes; HeLa Cells; Humans; Microscopy, Fluorescence; Molecular Imaging; Molecular Sequence Data; Nanocomposites; Nucleolin; Phosphoproteins; Protein Binding; RNA-Binding Proteins; Silver; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles | 2012 |
Inhibitory effects of Ginsenoside Rb1 on apoptosis caused by HSV-1 in human glioma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Ginsenosides; Herpesvirus 1, Human; Humans; Neuroglia; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
Biocompatibility evaluation of cigarette and carbon papers used in repair of traumatic tympanic membrane perforations: experimental study.
Topics: Animals; Biocompatible Materials; Carbon; Cell Adhesion; Cell Proliferation; Fibroblasts; In Vitro Techniques; Mice; Microscopy, Electron, Scanning; Paper; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Turkey; Tympanic Membrane Perforation | 2013 |
Multi-walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells.
Topics: Alveolar Epithelial Cells; Cell Line; Cell Membrane; Cell Survival; Comet Assay; DNA Damage; Humans; L-Lactate Dehydrogenase; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microvilli; Mutagens; Nanotubes, Carbon; Tetrazolium Salts; Thiazoles | 2012 |
Evaluation of the neurotoxic/neuroprotective role of organoselenides using differentiated human neuroblastoma SH-SY5Y cell line challenged with 6-hydroxydopamine.
Topics: Antioxidants; Antiparkinson Agents; Cell Differentiation; Cell Line, Tumor; Cell Survival; Coloring Agents; Free Radical Scavengers; Glutathione; Humans; Neurites; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Organoselenium Compounds; Oxidopamine; Sympatholytics; Tetrazolium Salts; Thiazoles | 2012 |
Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain Injuries; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cells, Cultured; Cerebral Cortex; Cerebral Infarction; Disease Models, Animal; Electroacupuncture; Embryo, Mammalian; Gene Expression Regulation; Glucose; HMGB1 Protein; Hypoxia; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Injections, Intraventricular; L-Lactate Dehydrogenase; Male; Neurons; Neuroprotective Agents; Phosphopyruvate Hydratase; Protein Binding; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2012 |
Synthesis, characterization and cytotoxic activity of new salicylaldehyde benzoylhydrazone derivatives as potential anti-proliferative agents.
Topics: Antineoplastic Agents; Benzaldehydes; Cell Line, Tumor; Coloring Agents; HL-60 Cells; Humans; Hydrazones; Indicators and Reagents; K562 Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Quantum Theory; Solubility; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2011 |
Comparative study of toxicological and cell cycle effects of okadaic acid and dinophysistoxin-2 in primary rat hepatocytes.
Topics: Analysis of Variance; Animals; Blotting, Western; Caspase 3; Cell Cycle; Cell Proliferation; Flow Cytometry; Hepatocytes; L-Lactate Dehydrogenase; Microscopy, Confocal; Okadaic Acid; Pyrans; Rats; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2012 |
Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems.
Topics: Adjuvants, Pharmaceutic; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility; Humans; Imidazoles; Keratinocytes; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2012 |
Three new steroidal glycosides from roots of Reineckia carnea.
Topics: Antineoplastic Agents; Glycosides; Hep G2 Cells; Humans; Liliaceae; Magnetic Resonance Spectroscopy; Mass Spectrometry; MCF-7 Cells; Molecular Structure; Plant Extracts; Plant Roots; Spirostans; Sterols; Tetrazolium Salts; Thiazoles | 2013 |
Cytotoxic effects exerted by Tritrichomonas foetus pseudocysts.
Topics: Animals; Cell Line; Cell Survival; Colorimetry; Dogs; Epithelial Cells; Microscopy, Electron; Spores, Protozoan; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tritrichomonas foetus | 2012 |
MiR-122 increases sensitivity of drug-resistant BEL-7402/5-FU cells to 5-fluorouracil via down-regulation of bcl-2 family proteins.
Topics: Antimetabolites; bcl-X Protein; Blotting, Western; Cell Death; Cell Line, Tumor; Coloring Agents; Down-Regulation; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Genetic Vectors; Humans; Microarray Analysis; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Protein p53 | 2011 |
Effect of matrigel on the osteogenic potential of canine adipose tissue-derived mesenchymal stem cells.
Topics: Adipose Tissue; Animals; Calcium Phosphates; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Collagen; Dogs; Drug Combinations; Laminin; Mesenchymal Stem Cells; Osteogenesis; Proteoglycans; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2012 |
Hijikia fusiforme protects against ovariectomy-induced bone loss in rats.
Topics: Acid Phosphatase; Administration, Oral; Alkaline Phosphatase; Animals; Biomarkers; Bone Density; Bone Resorption; Cell Differentiation; Cell Line; Cell Proliferation; Collagen Type I; Female; Humans; Isoenzymes; Mice; Osteocalcin; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Peptides; Phaeophyceae; RANK Ligand; Rats; Rats, Sprague-Dawley; Tartrate-Resistant Acid Phosphatase; Tetrazolium Salts; Thiazoles | 2012 |
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Survival; Citric Acid; D-Amino-Acid Oxidase; Electrophoresis, Polyacrylamide Gel; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Immunoblotting; Lactic Acid; Oxidative Stress; Pyruvates; Pyruvic Acid; Tetrazolium Salts; Thiazoles | 2012 |
Protective effect of recombinant hirudin variant III against galactose-mediated rat lens epithelial cell damage.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Survival; Cells, Cultured; DNA Fragmentation; Epithelial Cells; Fibrinolytic Agents; Flow Cytometry; Galactose; Glutathione; Hirudins; Lens, Crystalline; Male; Malondialdehyde; Oxidoreductases; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2012 |
Apoptosis of rat ovarian granulosa cells by 2,5-hexanedione in vitro and its relevant gene expression.
Topics: Analysis of Variance; Animals; Apoptosis; Apoptosis Regulatory Proteins; Coloring Agents; Female; Fluorescent Antibody Technique; Gene Expression; Gonadotropins, Equine; Granulosa Cells; Hexanones; In Situ Nick-End Labeling; Microscopy, Fluorescence; Neurotoxins; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transcription Factor RelA | 2013 |
Antimicrobial properties and cytotoxicity of an antimicrobial monomer for application in prosthodontics.
Topics: Acrylic Resins; Animals; Anti-Infective Agents; Anti-Infective Agents, Local; Bacterial Adhesion; Bacterial Load; Candida; Candida albicans; Candida glabrata; Cetylpyridinium; Colony Count, Microbial; Coloring Agents; Denture Bases; Fibroblasts; L Cells; Lacticaseibacillus casei; Materials Testing; Methacrylates; Methylmethacrylate; Mice; Microbial Sensitivity Tests; Polymerization; Pyridinium Compounds; Quaternary Ammonium Compounds; Staphylococcus aureus; Streptococcus mutans; Tetrazolium Salts; Thiazoles | 2012 |
Attenuation of influenza virus infectivity with herbal-marine compound (HESA-A): an in vitro study in MDCK cells.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Dogs; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Immunologic Factors; Interleukin-6; Orthomyxoviridae; Plant Preparations; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Viral Load; Virulence | 2012 |
Cytotoxicity comparison of three current direct pulp-capping agents with a new bioceramic root repair putty.
Topics: Adult; Calcium Fluoride; Calcium Hydroxide; Calcium Phosphates; Cell Culture Techniques; Cell Line; Cell Survival; Colorimetry; Coloring Agents; Culture Media, Conditioned; Drug Combinations; Fibroblasts; Humans; Minerals; Organic Chemicals; Oxides; Pulp Capping and Pulpectomy Agents; Silicates; Skin; Tantalum; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Zirconium | 2012 |
Effects of simvastain and enamel matrix derivative on Portland cement with bismuth oxide-induced growth and odontoblastic differentiation in human dental pulp cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Anthraquinones; Biocompatible Materials; Bismuth; Calcification, Physiologic; Calcium Compounds; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Dental Cements; Dental Enamel Proteins; Dental Pulp; Drug Combinations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Materials Testing; Odontoblasts; Odontogenesis; Osteocalcin; Osteopontin; Oxides; Pulp Capping and Pulpectomy Agents; Reverse Transcriptase Polymerase Chain Reaction; Silicates; Simvastatin; Sp7 Transcription Factor; Tetrazolium Salts; Thiazoles; Transcription Factors | 2012 |
MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets.
Topics: Cell Survival; Cytoplasmic Vesicles; Fluorescent Dyes; Formazans; HeLa Cells; Humans; Lipids; Molecular Structure; Particle Size; Quantitative Structure-Activity Relationship; Solubility; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
MDM2 antagonism by nutlin-3 induces death in human medulloblastoma cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Coloring Agents; Doxorubicin; Humans; Imidazoles; Medulloblastoma; Piperazines; Proto-Oncogene Proteins c-mdm2; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2012 |
The multidrug resistant modulator HZ08 reverses multidrug resistance via P-glycoprotein inhibition and apoptosis sensitization in human epidermoid carcinoma cell line KBV200.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Isoquinolines; KB Cells; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles | 2012 |
PCL films incorporated with paclitaxel/5-fluorouracil: Effects of formulation and spacial architecture on drug release.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coloring Agents; Delayed-Action Preparations; Diffusion; Drug-Eluting Stents; Female; Fluorouracil; Mice; Microscopy, Electron, Scanning; Paclitaxel; Polyesters; Polyethylene Glycols; Solubility; Spectrophotometry, Ultraviolet; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2012 |
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Butyrates; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvates; Tetrazolium Salts; Thiazoles | 2012 |
A cell-based assay for screening spindle checkpoint inhibitors.
Topics: Antineoplastic Agents; Aurora Kinases; Blotting, Western; Cell Cycle; Cell Cycle Checkpoints; Cell Line; Coloring Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorescent Antibody Technique; HeLa Cells; High-Throughput Screening Assays; Humans; Mitotic Index; Nocodazole; Protein Serine-Threonine Kinases; Purines; Roscovitine; Spindle Apparatus; Tetrazolium Salts; Thiazoles | 2012 |
Lysozyme-loaded, electrospun chitosan-based nanofiber mats for wound healing.
Topics: Animals; Bandages; Calorimetry, Differential Scanning; Cell Survival; Chitosan; Coloring Agents; Edetic Acid; Fibroblasts; Humans; Male; Micrococcus; Microscopy, Electron, Scanning; Muramidase; Nanofibers; Polyvinyl Alcohol; Rats; Rats, Wistar; Solubility; Tetrazolium Salts; Thiazoles; Wound Healing | 2012 |
Regulation of cell proliferation of human induced pluripotent stem cell-derived mesenchymal stem cells via ether-à-go-go 1 (hEAG1) potassium channel.
Topics: Cell Proliferation; Cells, Cultured; Coloring Agents; Ether-A-Go-Go Potassium Channels; Humans; Induced Pluripotent Stem Cells; Membrane Potentials; Mesenchymal Stem Cells; Tetrazolium Salts; Thiazoles | 2012 |
Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Female; Gene Expression Regulation; Humans; In Vitro Techniques; Janus Kinase 2; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Pentacyclic Triterpenes; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Triterpenes; Vanadates | 2012 |
Tetrahydrofuran as solvent in dental adhesives: cytotoxicity and dentin bond stability.
Topics: Acetone; Adhesiveness; Animals; Cattle; Colorimetry; Coloring Agents; Dental Bonding; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Ethanol; Fibroblasts; Furans; Materials Testing; Methacrylates; Mice; NIH 3T3 Cells; Random Allocation; Solvents; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2013 |
Endoplasmic reticulum stress impairs insulin signaling through mitochondrial damage in SH-SY5Y cells.
Topics: Adenosine Triphosphate; Apoptosis; Atrazine; Blotting, Western; Cell Line; Coloring Agents; Endoplasmic Reticulum Stress; Fluoresceins; Herbicides; Humans; Insulin; Microarray Analysis; Mitochondria; Mitochondrial Membranes; Neurons; Oxygen Consumption; Real-Time Polymerase Chain Reaction; Receptor Cross-Talk; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma.
Topics: Acetone; Amines; Antineoplastic Agents; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Delayed-Action Preparations; Disaccharides; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Fluorouracil; Galactose; Glycerides; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Nanoparticles; Oleic Acid; Particle Size; Polysorbates; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2012 |
A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Cyanates; Glucose; Hippocampus; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Peptide Fragments; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2012 |
In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Leishmania infantum; Macrophages; Mice; Nanoparticles; Polyesters; Polymers; Quinolones; Tetrazolium Salts; Thiazoles | 2012 |
Bioactive component, cantharidin from Mylabris cichorii and its antitumor activity against Ehrlich ascites carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cantharidin; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Coleoptera; Drug Screening Assays, Antitumor; Kidney; L-Lactate Dehydrogenase; Lethal Dose 50; Methanol; Mice; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Tetrazolium Salts; Thiazoles | 2012 |
Facile synthesis of triterpenoid saponins bearing β-Glu/Gal-(1→3)-β-GluA methyl ester and their cytotoxic activities.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Disaccharides; Flow Cytometry; Glycyrrhetinic Acid; Humans; Membrane Potential, Mitochondrial; Molecular Structure; Neoplasms; Reactive Oxygen Species; Saponins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid | 2012 |
A comparison of biocompatibility and osseointegration of ceramic and titanium implants: an in vivo and in vitro study.
Topics: Animals; Biocompatible Materials; Bone Matrix; Bromodeoxyuridine; Cell Culture Techniques; Cell Proliferation; Cell Survival; Ceramics; Coloring Agents; Dental Implants; Dental Materials; Dental Prosthesis Design; Female; Fluoresceins; Fluorescent Dyes; Frontal Bone; Humans; L-Lactate Dehydrogenase; Materials Testing; Microscopy, Electron, Scanning; Models, Animal; Osseointegration; Osteoblasts; Osteocalcin; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Titanium; Zirconium | 2012 |
Inhibition of transient receptor potential melastain 7 channel increases HSCs apoptosis induced by TRAIL.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Boron Compounds; Caspase 3; DNA Primers; Extracellular Matrix; Flow Cytometry; Gadolinium; Hepatic Stellate Cells; Liver Cirrhosis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; TRPM Cation Channels | 2012 |
Photothermal effects of folate-conjugated Au nanorods on HepG2 cells.
Topics: Cell Survival; Flow Cytometry; Folic Acid; Gold; Hep G2 Cells; Hepatocytes; Hot Temperature; Humans; Light; Microscopy, Atomic Force; Nanotubes; Phototherapy; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
17β-estradiol attenuates neural cell apoptosis through inhibition of JNK phosphorylation in SCI rats and excitotoxicity induced by glutamate in vitro.
Topics: Analysis of Variance; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Estradiol; Female; Glutamic Acid; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Cytotoxicity and genotoxicity of root canal sealers based on mineral trioxide aggregate.
Topics: Aluminum Compounds; Animals; Biocompatible Materials; Calcium Compounds; Cell Line; Cell Survival; Coloring Agents; Cricetinae; Cytotoxins; Dose-Response Relationship, Drug; Drug Combinations; Epoxy Resins; Fibroblasts; Materials Testing; Micronucleus Tests; Mutagens; Oxides; Root Canal Filling Materials; Silicates; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.
Topics: Adenine; Adjuvants, Immunologic; Aldehydes; Analysis of Variance; Animals; Asparagine; Autophagy; Brain; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Lithium Chloride; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphorylation; Serine; Sirolimus; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds; Vacuoles | 2012 |
Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Everolimus; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Nude; Sirolimus; Stem Cells; Taxoids; Tetrazolium Salts; Thiazoles | 2012 |
Chemical constituents of Euphorbia tangutica.
Topics: Analysis of Variance; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Ergosterol; Euphorbia; HL-60 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phorbol Esters; Plant Extracts; Tetrazolium Salts; Thiazoles | 2012 |
A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Cloning, Molecular; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Humans; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Nitric Oxide; Peptide Fragments; Peptide Library; Peptides; Phagocytosis; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
The differential proliferative ability of satellite cells in Lantang and Landrace pigs.
Topics: Animals; Blotting, Western; Cell Cycle; Cell Proliferation; Flow Cytometry; Muscle, Skeletal; MyoD Protein; Myogenic Regulatory Factor 5; Myogenin; Myostatin; PAX7 Transcription Factor; Real-Time Polymerase Chain Reaction; Satellite Cells, Skeletal Muscle; Smad3 Protein; Species Specificity; Sus scrofa; Tetrazolium Salts; Thiazoles | 2012 |
Prevention and therapy of hepatocellular carcinoma by vaccination with TM4SF5 epitope-CpG-DNA-liposome complex without carriers.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Carcinoma, Hepatocellular; CD4-Positive T-Lymphocytes; Cell Line, Tumor; DNA Primers; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunization; Immunoglobulin G; Immunohistochemistry; Immunotherapy; Interleukin-12; Kaplan-Meier Estimate; Liposomes; Liver Neoplasms; Membrane Proteins; Mice; Oligodeoxyribonucleotides; Tetrazolium Salts; Thiazoles | 2012 |
α-Mangostin induces apoptosis and suppresses differentiation of 3T3-L1 cells via inhibiting fatty acid synthase.
Topics: 3T3-L1 Cells; Analysis of Variance; Animals; Apoptosis; Azo Compounds; Bisbenzimidazole; Cell Differentiation; Cell Membrane Permeability; Chromatin Assembly and Disassembly; Fatty Acid Synthases; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Mice; Palmitic Acids; Tetrazolium Salts; Thiazoles; Xanthones | 2012 |
Activation of PI3K/AKT and MAPK pathway through a PDGFRβ-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Immunohistochemistry; Liver Neoplasms; Male; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Sirolimus; Tetrazolium Salts; Thiazoles | 2012 |
Phage display against corneal epithelial cells produced bioactive peptides that inhibit Aspergillus adhesion to the corneas.
Topics: Analysis of Variance; Animals; Aspergillus; Cell Adhesion; Computational Biology; DNA Primers; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Epithelium, Corneal; Host-Pathogen Interactions; Humans; Interleukin-17; Keratitis; Mice; Myeloid Differentiation Factor 88; Peptide Library; Peptides; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Stromal Cells; Tetrazolium Salts; Thiazoles | 2012 |
Dexrazoxane shows cytoprotective effects in zoledronic acid-treated human cells in vitro and in the rabbit tibia model in vivo.
Topics: Animals; Apoptosis; Bone Density Conservation Agents; Bone Resorption; Cell Culture Techniques; Cell Line; Cell Shape; Cell Survival; Collagen; Coloring Agents; Cytoprotection; Diphosphonates; Drug Carriers; Durapatite; Female; Fibroblasts; Fluoresceins; Fluorescent Dyes; Gingiva; Humans; Imidazoles; Models, Animal; Osteoblasts; Osteogenesis; Protective Agents; Rabbits; Razoxane; Tetrazolium Salts; Thiazoles; Tibia; Zoledronic Acid | 2012 |
Chi-square analysis of the reduction of ATP levels in L-02 hepatocytes by hexavalent chromium.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Carcinogens, Environmental; Cell Culture Techniques; Cell Survival; Chi-Square Distribution; China; Chromium; Coloring Agents; Hepatocytes; Humans; Mitochondria, Liver; Tetrazolium Salts; Thiazoles | 2012 |
Jeju ground water containing vanadium induced immune activation on splenocytes of low dose γ-rays-irradiated mice.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cobalt Radioisotopes; Coloring Agents; Comet Assay; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluoresceins; Free Radical Scavengers; Gamma Rays; Groundwater; Interferon-gamma; Mice; Reactive Oxygen Species; Republic of Korea; Spleen; Tetrazolium Salts; Thiazoles; Thymidine; Vanadates; Vanadium | 2012 |
Evaluation of cytotoxicity and up-regulation of gelatinases in fibroblast cells by three root repair materials.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Calcium Compounds; Calcium Hydroxide; Cell Culture Techniques; Cell Survival; Coloring Agents; Drug Combinations; Fibroblasts; Materials Testing; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2012 |
Validation of a new metabolic marker to assess the vascular viability of vitrified whole sheep ovaries.
Topics: Animals; Coloring Agents; Cryopreservation; Cryoprotective Agents; Deoxyglucose; Female; Glucose; Muscle, Smooth, Vascular; Ovary; Pentose Phosphate Pathway; Sheep; Tetrazolium Salts; Thiazoles | 2012 |
The renal v-ATPase a4 subunit is expressed in specific subtypes of human gliomas.
Topics: Adenosine Triphosphatases; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Epilepsy; Gene Expression Regulation, Neoplastic; Glioma; Humans; RNA Interference; RNA, Messenger; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Transfection; Vacuolar Proton-Translocating ATPases | 2012 |
Rapid assessment of antiviral activity and cytotoxicity of silver nanoparticles using a novel application of the tetrazolium-based colorimetric assay.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Colorimetry; HIV-1; Humans; Microbial Sensitivity Tests; Nanoparticles; Silver; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
Phencyclidine-induced decrease of synaptic connectivity via inhibition of BDNF secretion in cultured cortical neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Patch-Clamp Techniques; Phencyclidine; Rats; Rats, Wistar; Receptor, trkB; Receptors, Glutamate; RNA, Messenger; Signal Transduction; Synapses; Synaptic Potentials; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
An evaluation of the safety and feasibility of convection-enhanced delivery of carboplatin into the white matter as a potential treatment for high-grade glioma.
Topics: Animals; Antineoplastic Agents; Brain; Carboplatin; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Feasibility Studies; Glial Fibrillary Acidic Protein; Glioma; Half-Life; Humans; Magnetic Resonance Imaging; Male; Nerve Fibers, Myelinated; Rats; Rats, Wistar; Spectrophotometry, Atomic; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2012 |
Gas-filled phospholipid nanoparticles conjugated with gadolinium play a role as a potential theragnostics for MR-guided HIFU ablation.
Topics: Animals; Biocompatible Materials; Contrast Media; Gadolinium; Gadolinium DTPA; Gases; High-Intensity Focused Ultrasound Ablation; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phantoms, Imaging; Phospholipids; Phosphorus; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2012 |
Effect of triethylene glycol dimethacrylate on the cytotoxicity, cyclooxygenase-2 expression and prostanoids production in human dental pulp cells.
Topics: Annexin A5; Apoptosis; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Culture Techniques; Cell Cycle; Cell Death; Cell Proliferation; Cell Shape; Coloring Agents; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclooxygenase 2; Dental Materials; Dental Pulp; Dinoprost; Dinoprostone; Enzyme Inhibitors; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Necrosis; Polyethylene Glycols; Polymethacrylic Acids; Propidium; Prostaglandins; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Molecular combination of the dopamine and serotonin scaffolds yield in novel antipsychotic drug candidates - characterization by in vivo experiments.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Biological Availability; Calcium; Catalepsy; Cells, Cultured; Dopamine; Female; Haloperidol; Humans; Motor Activity; Neuroglia; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Serotonin; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2012 |
Extracellular heat shock protein 72 protects schwann cells from hydrogen peroxide-induced apoptosis.
Topics: Animals; Annexin A5; Apoptosis; Caspase 3; Caspase 9; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; HSP72 Heat-Shock Proteins; Hydrogen Peroxide; In Situ Nick-End Labeling; Oxidants; Proto-Oncogene Proteins c-bcl-2; Rats; Schwann Cells; Tetrazolium Salts; Thiazoles; Up-Regulation | 2012 |
Essential role of interleukin-6 in post-stroke angiogenesis.
Topics: Analysis of Variance; Angiogenic Proteins; Animals; Bone Marrow Transplantation; Brain; Calcium-Binding Proteins; Cells, Cultured; Cerebral Cortex; Cytokine Receptor gp130; Cytokines; Disease Models, Animal; Embryo, Mammalian; Endothelial Cells; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Gait Disorders, Neurologic; Gene Expression Profiling; Gene Expression Regulation; Glucose; Green Fluorescent Proteins; Hypoxia; Infarction, Middle Cerebral Artery; Interleukin-6; Mice; Mice, Knockout; Microfilament Proteins; Neovascularization, Pathologic; Neuroglia; Neurons; Oligonucleotide Array Sequence Analysis; Perfusion Imaging; Receptor, trkB; Rotarod Performance Test; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles | 2012 |
Microstructure, mechanical properties, biocorrosion behavior, and cytotoxicity of as-extruded Mg-Nd-Zn-Zr alloy with different extrusion ratios.
Topics: Alloys; Animals; Biocompatible Materials; Body Fluids; Cell Survival; Corrosion; Electrons; Humans; Magnesium; Materials Testing; Mice; Microscopy, Electron, Scanning; Neodymium; Stress, Mechanical; Temperature; Tetrazolium Salts; Thiazoles; Zinc; Zirconium | 2012 |
Self-assembled human serum albumin-coated complexes for gene delivery with improved transfection.
Topics: Adsorption; Cell Line; Cell Survival; Coloring Agents; Dendrimers; DNA; Electrochemistry; Electrophoresis, Agar Gel; Flow Cytometry; Gene Transfer Techniques; Green Fluorescent Proteins; Hemolysis; Humans; Light; Microscopy, Electron, Transmission; Particle Size; Plasmids; Scattering, Radiation; Serum Albumin; Tetrazolium Salts; Thiazoles; Transfection | 2012 |
The proteasome inhibitor bortezomib reverses P-glycoprotein-mediated leukemia multi-drug resistance through the NF-kappaB pathway.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Boronic Acids; Bortezomib; Cell Survival; Coloring Agents; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; I-kappa B Proteins; Indicators and Reagents; K562 Cells; NF-kappa B; Polymerase Chain Reaction; Proteasome Inhibitors; Pyrazines; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor RelA | 2012 |
The effects of Syzygium aromaticum-derived oleanolic acid on kidney function of male Sprague-Dawley rats and on kidney and liver cell lines.
Topics: Analysis of Variance; Animals; Cell Line; Comet Assay; Creatinine; Diabetes Mellitus, Experimental; Electrophoresis, Agar Gel; Glomerular Filtration Rate; Kidney Tubules, Proximal; Liver; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Sprague-Dawley; Sodium; Syzygium; Tetrazolium Salts; Thiazoles | 2012 |
Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells.
Topics: Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Cell Line; Cell Proliferation; Cell Survival; Cytoskeleton; Dose-Response Relationship, Drug; Endocannabinoids; Epithelial Cells; Gene Expression Regulation; Glycerides; Humans; Lipids; Models, Biological; Necrosis; Polyunsaturated Alkamides; Receptors, Cannabinoid; RNA Interference; Sweat Glands; Tetrazolium Salts; Thiazoles | 2012 |
Proliferation and multilineage potential of CXCR4-positive human dental pulp cells in vitro.
Topics: Adipogenesis; Alkaline Phosphatase; Anthraquinones; Azo Compounds; Calcification, Physiologic; Calcium; Cell Count; Cell Culture Techniques; Cell Lineage; Cell Proliferation; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Collagen Type I; Coloring Agents; Culture Media; Dental Pulp; Extracellular Matrix Proteins; Humans; Mesenchymal Stem Cells; Odontogenesis; Osteocalcin; Phosphoproteins; PPAR gamma; Receptors, CXCR4; Sialoglycoproteins; Stem Cells; Tetrazolium Salts; Thiazoles | 2012 |
Cytotoxic effects of cadmium in mammary epithelial cells: protective role of the macrocycle [15]pyN5.
Topics: Antimetabolites; Bromodeoxyuridine; Cadmium Chloride; Cell Line, Tumor; Cell Survival; Chelating Agents; Coloring Agents; Dose-Response Relationship, Drug; Epithelial Cells; Female; Fluorometry; Gentian Violet; Humans; Macrocyclic Compounds; Mammary Glands, Human; Reactive Oxygen Species; Tetrazolium Salts; Thermodynamics; Thiazoles | 2012 |
Hyaluronic acid L-cysteine conjugate exhibits controlled-release potential for mucoadhesive drug delivery.
Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Survival; Chymotrypsin; Coloring Agents; Cysteine; Delayed-Action Preparations; Dogs; Drug Delivery Systems; Excipients; Hyaluronic Acid; Intestines; Mucous Membrane; Protease Inhibitors; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tissue Adhesives; Trypsin Inhibitors | 2012 |
Overexpression of cellular prion protein (PrP(C)) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ₁₋₄₀) administration in mice.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Cognition Disorders; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Peptide Fragments; Prion Proteins; Prions; Propidium; Proto-Oncogene Proteins c-bcl-2; Reaction Time; Tetrazolium Salts; Thiazoles | 2012 |
In vitro skin corrosion: Human skin model test - A validation study.
Topics: Animal Testing Alternatives; Cell Survival; Coloring Agents; Humans; In Vitro Techniques; Irritants; Oxidation-Reduction; Skin; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles | 2012 |
Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling.
Topics: Blotting, Western; Cell Count; Cell Division; Cell Line; Coloring Agents; DNA Damage; Epithelial Cells; Flow Cytometry; G2 Phase; Genetic Vectors; Glutathione; Humans; Kidney; Lentivirus; Micronucleus Tests; Nanoparticles; NF-E2-Related Factor 2; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Silver; Tetrazolium Salts; Thiazoles | 2012 |
Effects of cadmium chloride on the cultured human lens epithelial cells.
Topics: Apoptosis; Cadmium Chloride; Caspase 8; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Lens, Crystalline; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
Effects of cerium oxide nanoparticles to fish and mammalian cell lines: An assessment of cytotoxicity and methodology.
Topics: Animals; Cell Line; Cell Survival; Cerium; L-Lactate Dehydrogenase; Nanoparticles; Neutral Red; Oncorhynchus mykiss; Particle Size; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2012 |
The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Blotting, Western; Cell Line, Tumor; Circular Dichroism; Electron Spin Resonance Spectroscopy; Fluorenes; Fluorescent Antibody Technique; Free Radical Scavengers; Humans; Microscopy, Atomic Force; Models, Biological; Molecular Structure; Nitrogen Oxides; Spin Labels; Tetrazolium Salts; Thiazoles | 2012 |
Immobilisation of heparin on bacterial cellulose-chitosan nano-fibres surfaces via the cross-linking technique.
Topics: Animals; Biocompatible Materials; Cell Line; Cellulose; Chitosan; Gluconacetobacter xylinus; Heparin; Humans; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanofibers; Porosity; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; X-Ray Diffraction | 2012 |
Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Camptothecin; Cell Line, Tumor; Coloring Agents; Dimethyl Sulfoxide; Drug Screening Assays, Antitumor; Emodin; Gene Expression; Humans; Lignans; Naphthoquinones; Rotenone; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Tumor Suppressor Protein p53; Zebrafish | 2012 |
Salusin-β accelerates inflammatory responses in vascular endothelial cells via NF-κB signaling in LDL receptor-deficient mice in vivo and HUVECs in vitro.
Topics: Animals; Blood Pressure; Cell Adhesion; Cholesterol, Dietary; Coloring Agents; DNA Primers; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Mice; Mice, Knockout; Monocytes; NADPH Oxidases; NF-kappa B; Oxidative Stress; Real-Time Polymerase Chain Reaction; Receptors, LDL; Signal Transduction; Tetrazolium Salts; Thiazoles; Vascular Cell Adhesion Molecule-1; Vasculitis | 2012 |
Uranyl nitrate-exposed rat alveolar macrophages cell death: influence of superoxide anion and TNF α mediators.
Topics: Animals; Apoptosis; Azo Compounds; Caspase 3; Cell Death; Cell Nucleus; Cells, Cultured; Coloring Agents; Immunohistochemistry; Inflammation Mediators; Macrophages, Alveolar; Male; Phagocytosis; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Signal Transduction; Superoxides; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Uranyl Nitrate | 2012 |
The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons.
Topics: Abietanes; Amyloid beta-Peptides; Animals; Blotting, Western; Calpain; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytoplasm; Female; Immunohistochemistry; Mice; Microscopy, Electron, Transmission; Neurons; Neuroprotective Agents; Peptide Fragments; Phosphorylation; Phosphotransferases; Pregnancy; Protein Transport; Signal Transduction; tau Proteins; Tetrazolium Salts; Thiazoles | 2012 |
Apoptosis-inducing effect of the DR5 monoclonal antibody, D-6, alone or in combination with cisplatin, on A2780 ovarian cancer cells.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caspase 8; Cell Line, Tumor; Cisplatin; Culture Media; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Mice; Ovarian Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand | 2012 |
Kale extract increases glutathione levels in V79 cells, but does not protect them against acute toxicity induced by hydrogen peroxide.
Topics: Animals; Antioxidants; Brassica; Butterflies; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Complex Mixtures; Cricetinae; Feces; Fibroblasts; Flavonoids; Glutathione; Glycosides; Hydrogen Peroxide; Larva; Oxidative Stress; Phenols; Plant Extracts; Tetrazolium Salts; Thiazoles | 2012 |
Virosecurinine induces apoptosis by affecting Bcl-2 and Bax expression in human colon cancer SW480 cells.
Topics: Actins; Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Azepines; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Coloring Agents; Euphorbiaceae; Gene Expression; Humans; Lactones; Piperidines; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2012 |
Cytotoxicity induced by exposure to natural and synthetic tremolite asbestos: an in vitro pilot study.
Topics: Actins; Apoptosis; Asbestos; Asbestos, Amphibole; Asbestos, Crocidolite; beta Catenin; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Survival; Cytoskeleton; Humans; Immunohistochemistry; Iron; Microscopy, Electron; Mitosis; Necrosis; Phalloidine; Pilot Projects; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor A; X-Rays | 2013 |
Use of the quorum sensing inhibitor furanone C-30 to interfere with biofilm formation by Streptococcus mutans and its luxS mutant strain.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Colorimetry; Furans; Gene Expression Profiling; Microbial Sensitivity Tests; Microscopy, Confocal; Quorum Sensing; Real-Time Polymerase Chain Reaction; Staining and Labeling; Streptococcus mutans; Tetrazolium Salts; Thiazoles | 2012 |
The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells.
Topics: Apoptosis; Benzalkonium Compounds; Caspase 3; Cell Line; Cell Membrane Permeability; Cell Survival; Cloprostenol; Cornea; Epithelial Cells; Humans; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Latanoprost; NF-kappa B; Ophthalmic Solutions; Polymers; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Tetrazolium Salts; Thiazoles; Travoprost | 2012 |
Myoglobin-induced apoptosis: two pathways related to endoplasmic reticulum stress.
Topics: Acute Kidney Injury; Apoptosis; Blotting, Western; Caspases; Cell Survival; Cells, Cultured; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Flow Cytometry; Humans; Lactose; Microscopy, Fluorescence; Myoglobin; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
Scopararanes C-G: new oxygenated pimarane diterpenes from the marine sediment-derived fungus Eutypella scoparia FS26.
Topics: Abietanes; Antibiotics, Antineoplastic; Cell Line, Tumor; Circular Dichroism; Coloring Agents; Culture Media; Drug Screening Assays, Antitumor; Fermentation; Geologic Sediments; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Seawater; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles; Xylariales | 2012 |
Activation of the dormant secondary metabolite production by introducing gentamicin-resistance in a marine-derived Penicillium purpurogenum G59.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Aquatic Organisms; Bioengineering; Cell Proliferation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Coloring Agents; Drug Resistance, Bacterial; Fermentation; Gentamicins; Humans; K562 Cells; Microbial Sensitivity Tests; Multigene Family; Mutation; Penicillium; Phenotype; Ribosomes; Spores, Fungal; Tetrazolium Salts; Thiazoles | 2012 |
Cellular and transcriptional responses of Crassostrea gigas hemocytes exposed in vitro to brevetoxin (PbTx-2).
Topics: Animals; Antioxidants; Apoptosis; Cell Separation; Cell Survival; Coloring Agents; Crassostrea; DNA, Complementary; Hemocytes; Hemolymph; Inactivation, Metabolic; Marine Toxins; Neutral Red; Oxocins; Real-Time Polymerase Chain Reaction; RNA; Stress, Physiological; Tetrazolium Salts; Thiazoles; Transcription, Genetic | 2012 |
Locally released small (non-protein) ninhydrin-reacting molecules underlie developmental differences of cultured medullary versus spinal dorsal horn neurons.
Topics: Animals; Animals, Newborn; Cell Death; Cell Growth Processes; Cells, Cultured; Cerebral Cortex; Chromatography, Gel; Coculture Techniques; Culture Media, Conditioned; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Glutamic Acid; In Situ Nick-End Labeling; Medulla Oblongata; Neural Inhibition; Neurofibromin 1; Neurofibromin 2; Neurons; Ninhydrin; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Spinal Cord; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Cytotoxic effects of denture adhesives on primary human oral keratinocytes, fibroblasts and permanent L929 cell lines.
Topics: Adhesives; Alginates; Animals; Carboxymethylcellulose Sodium; Cell Line; Cell Survival; Cells, Cultured; Coloring Agents; Denture Retention; Fibroblasts; Gingiva; Glucuronic Acid; Hexuronic Acids; Humans; Keratinocytes; Maleates; Mice; Mouth Mucosa; Polyethylenes; Tetrazolium Salts; Thiazoles | 2014 |
Isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/m cell cycle arrest and apoptosis.
Topics: Apoptosis; Aporphines; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Flow Cytometry; Humans; Liver Neoplasms; Papaveraceae; Phosphorylation; Phytotherapy; Plant Extracts; Protein Kinases; Protein Serine-Threonine Kinases; RNA Interference; Tetrazolium Salts; Thiazoles | 2012 |
Transthyretin aggregates induce production of reactive nitrogen species.
Topics: Acetophenones; Antioxidants; Carcinoma; Cell Line, Tumor; Humans; Prealbumin; Reactive Nitrogen Species; Tetrazolium Salts; Thiazoles | 2013 |
Comparative cyto-genotoxicity assessment of functionalized and pristine multiwalled carbon nanotubes on human lung epithelial cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Epithelial Cells; Humans; Hydroxylation; L-Lactate Dehydrogenase; Lung; Microscopy, Electron, Transmission; Nanotubes, Carbon; Tetrazolium Salts; Thiazoles | 2012 |
TFF1 inhibits proliferation and induces apoptosis of gastric cancer cells in vitro.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Down-Regulation; Epithelial Cells; Flow Cytometry; Gastric Mucosa; Humans; Immunohistochemistry; Plasmids; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Trefoil Factor-1; Tumor Suppressor Proteins | 2012 |
Growth inhibition by caffeic acid, one of the phenolic constituents of honey, in HCT 15 colon cancer cells.
Topics: Apoptosis; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Honey; Humans; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Generic delivery of payload of nanoparticles intracellularly via hybrid polymer capsules for bioimaging applications.
Topics: Capsules; Drug Delivery Systems; Flow Cytometry; HeLa Cells; Humans; Metal Nanoparticles; Microscopy, Confocal; Microscopy, Electron, Transmission; Polyamines; Polymers; Polystyrenes; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2012 |
Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites.
Topics: Aminoquinolines; Animals; Antimalarials; Cell Line, Tumor; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Hemeproteins; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Malaria; Mice; Models, Molecular; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Protein Conformation; Tetrazolium Salts; Thiazoles | 2012 |
Random/aligned electrospun PCL/PCL-collagen nanofibrous membranes: comparison of neural differentiation of rat AdMSCs and BMSCs.
Topics: Animals; Bone Marrow Cells; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cell Survival; Collagen; Culture Media; Epidermal Growth Factor; Fibroblast Growth Factor 2; Flow Cytometry; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanofibers; Neurons; Polyesters; Rats; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2012 |
Involvement of dopaminergic neuronal cystatin C in neuronal injury-induced microglial activation and neurotoxicity.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Conditioned; Cystatin C; Cytokines; Dieldrin; Dopaminergic Neurons; Fluorescent Antibody Technique; Glycosylation; Inflammation; Macrophage Activation; Microglia; MPTP Poisoning; Mutagens; Neurons; Neurotoxicity Syndromes; Nitrites; Proteomics; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
The effects of low dose X-irradiation on osteoblastic MC3T3-E1 cells in vitro.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Apoptosis; Bromodeoxyuridine; Calcification, Physiologic; Calcium; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 1 Subunit; Dose-Response Relationship, Radiation; Gene Expression; Mice; Osteoblasts; Osteocalcin; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2012 |
The inhibitory effect of CIL-102 on the growth of human astrocytoma cells is mediated by the generation of reactive oxygen species and induction of ERK1/2 MAPK.
Topics: Antineoplastic Agents; Astrocytoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Enzyme Induction; Glioblastoma; Humans; Mitogen-Activated Protein Kinase Kinases; Quinolines; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
[Comparison and analysis of in vitro cytotoxocity of different shengmai injections].
Topics: Animals; Cell Proliferation; Drugs, Chinese Herbal; Injections; Mice; Tetrazolium Salts; Thiazoles | 2012 |
REST controls self-renewal and tumorigenic competence of human glioblastoma cells.
Topics: Analysis of Variance; Animals; Annexin A5; Apoptosis; Blotting, Western; Cell Transformation, Neoplastic; Colorimetry; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Mice, SCID; MicroRNAs; Real-Time Polymerase Chain Reaction; Repressor Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2012 |
TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.
Topics: Animals; Cell Line; Cell Movement; Cell Polarity; Cell Proliferation; DNA Primers; Dogs; Epithelial-Mesenchymal Transition; Flow Cytometry; Gene Expression Regulation; Gene Knockdown Techniques; Immunoblotting; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors | 2012 |
CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells.
Topics: Apoptosis; Binding Sites; Breast Neoplasms; Calorimetry; Cell Line, Tumor; Cell Proliferation; Humans; Kinetics; Spectrometry, Fluorescence; Tetrazolium Salts; Thermodynamics; Thiazoles; Tubulin | 2012 |
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
Topics: Adenine; Alanine; alpha-Synuclein; Animals; Autophagy; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Lysosomes; Microscopy, Electron, Transmission; PC12 Cells; Phagosomes; Phosphoinositide-3 Kinase Inhibitors; Point Mutation; Proteasome Inhibitors; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Threonine; Transduction, Genetic; Trehalose; Up-Regulation | 2012 |
β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Analysis of Variance; Aspartic Acid Endopeptidases; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; MAP Kinase Kinase 4; Microscopy, Electron, Transmission; Neuroblastoma; Peptide Fragments; Reactive Oxygen Species; RNA Interference; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2012 |
A novel multifunctional nanocomposite C225-conjugated Fe3O4/Ag enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy.
Topics: Carcinoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Ferrosoferric Oxide; Humans; Microscopy, Electron, Transmission; Molecular Targeted Therapy; Nanocomposites; Nanotechnology; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Radiation-Sensitizing Agents; Silver; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Therapeutic efficacy of silibinin on human neuroblastoma cells: Akt and NF-κB expressions may play an important role in silibinin-induced response.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lethal Dose 50; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuroblastoma; NF-kappa B; Oncogene Protein v-akt; Protective Agents; Real-Time Polymerase Chain Reaction; Signal Transduction; Silybin; Silymarin; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 2012 |
Application of immunohistochemical staining to detect antigen destruction as a measure of tissue damage.
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Coloring Agents; Cross Reactions; Eosine Yellowish-(YS); Fixatives; Formaldehyde; Hematoxylin; Hot Temperature; Immunohistochemistry; Paraffin Embedding; Protein Denaturation; Protein Folding; Receptor, ErbB-2; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles; Tyrosine | 2012 |
ATP induces the death of developing avian retinal neurons in culture via activation of P2X7 and glutamate receptors.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Aspartic Acid; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Chick Embryo; Coloring Agents; Dose-Response Relationship, Drug; Ethidium; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Macrophages; Neuroglia; Receptors, Glutamate; Receptors, Purinergic P2X7; Retina; Retinal Neurons; Tetrazolium Salts; Thiazoles | 2013 |
Laser-induced modifications of gold nanoparticles and their cytotoxic effect.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Equipment Design; Gold; Kidney; Lasers; Metal Nanoparticles; Microscopy, Electron; Microscopy, Electron, Transmission; Nanotechnology; Phototherapy; Rats; Tetrazolium Salts; Thiazoles; Trypan Blue | 2012 |
Bone repair using periodontal ligament progenitor cell-seeded constructs.
Topics: Alkaline Phosphatase; Animals; Biomimetic Materials; Bone Regeneration; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Coloring Agents; Culture Media; Durapatite; Extracellular Matrix; Flow Cytometry; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Periodontal Ligament; Phenotype; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Skull; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering; Tissue Scaffolds; Up-Regulation | 2012 |
Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization.
Topics: Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Crystallization; Dimerization; Fluorescence Resonance Energy Transfer; Humans; Hydantoins; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2012 |
Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Cell Communication; Cell Differentiation; Cells, Cultured; Coculture Techniques; Dendrites; Dose-Response Relationship, Drug; Endocytosis; Exocytosis; Female; Green Fluorescent Proteins; Heterocyclic Compounds, 3-Ring; Hippocampus; Humans; Lysosomal-Associated Membrane Protein 2; Male; Membrane Glycoproteins; Microinjections; Microscopy, Electron, Transmission; Neocortex; Nerve Degeneration; Nerve Tissue Proteins; Neuroblastoma; Neuroglia; Neurons; Patch-Clamp Techniques; Peptide Fragments; rab5 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Rhodamines; Synaptic Transmission; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2012 |
Cytotoxicity of esthetic, metallic, and nickel-free orthodontic brackets: cellular behavior and viability.
Topics: Aluminum; Animals; Benzhydryl Compounds; Biocompatible Materials; Carbon Dioxide; Cell Culture Techniques; Cell Proliferation; Cell Survival; Ceramics; Chromium Alloys; Coloring Agents; Dental Alloys; Dental Materials; Esthetics, Dental; Fibroblasts; Mice; Nickel; NIH 3T3 Cells; Orthodontic Brackets; Phenols; Polycarboxylate Cement; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2012 |
Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells.
Topics: Carcinoma; Cell Line, Tumor; Disease Progression; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Lipids; Models, Chemical; Pancreatic Neoplasms; Phenotype; Phosphatidylethanolamines; RNA, Messenger; Telomerase; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2012 |
Ultraviolet A regulates the stemness of human adipose tissue-derived mesenchymal stem cells through downregulation of the HIF-1α via activation of PGE(2)-cAMP signaling.
Topics: Adipose Tissue; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Culture Media, Serum-Free; Cyclic AMP; Cysteine; Dinoprostone; Down-Regulation; Gene Expression Regulation; Homeodomain Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Nanog Homeobox Protein; NF-kappa B; Octamer Transcription Factor-3; Radiation-Protective Agents; RNA, Messenger; Signal Transduction; SOXB1 Transcription Factors; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2012 |
Mullerian inhibiting substance induces apoptosis of human endometrial stromal cells in endometriosis.
Topics: Annexin A5; Anti-Mullerian Hormone; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cells, Cultured; E2F Transcription Factors; Endometriosis; Endometrium; Female; Humans; Immunohistochemistry; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Retinoblastoma-Like Protein p107; Retinoblastoma-Like Protein p130; Stromal Cells; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2012 |
Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes.
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Cell Line; Coloring Agents; DNA; Doxorubicin; Drug Carriers; Female; Gene Expression; Liposomes; Macrophages; Mice; Mice, Inbred BALB C; NF-kappa B; Particle Size; Polyethylene Glycols; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcriptional Activation | 2012 |
Enhanced pulmonary absorption of recombinant human insulin by pulmonary surfactant and phospholipid hexadecanol tyloxapol through Calu-3 monolayers.
Topics: Absorption; Cell Line; Cell Line, Tumor; Epithelial Cells; Fluorescent Dyes; Humans; Insulin; L-Lactate Dehydrogenase; Lung; Microscopy, Electron, Transmission; Permeability; Phospholipids; Pulmonary Surfactants; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tight Junctions | 2012 |
4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte cultures.
Topics: Aged, 80 and over; Aldehydes; Alzheimer Disease; Animals; Astrocytes; Biological Transport, Active; Blotting, Western; Brain Chemistry; Cells, Cultured; Cognitive Dysfunction; Coloring Agents; Excitatory Amino Acid Transporter 2; Female; Glutamate Plasma Membrane Transport Proteins; Glutamates; Humans; Immunoprecipitation; Lipid Peroxidation; Male; Parahippocampal Gyrus; Rats; Tetrazolium Salts; Thiazoles | 2012 |
Ethanol influences on Bax associations with mitochondrial membrane proteins in neonatal rat cerebellum.
Topics: Administration, Inhalation; Animals; Animals, Newborn; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Central Nervous System Depressants; Cerebellum; Coculture Techniques; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hexokinase; Male; Mitochondrial ADP, ATP Translocases; Mitochondrial Proteins; Pregnancy; Protein Conformation; Rats; Rats, Long-Evans; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Voltage-Dependent Anion Channels | 2013 |
Effect of Mitofusin 2 on smooth muscle cells proliferation in hypoxic pulmonary hypertension.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Cyclin A; DNA; GTP Phosphohydrolases; Hypertension, Pulmonary; Hypoxia; Lung; Male; Membrane Proteins; Mitochondrial Proteins; Myocytes, Smooth Muscle; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2012 |
Effects of melatonin and its receptor antagonist on retinal pigment epithelial cells against hydrogen peroxide damage.
Topics: Antioxidants; Apoptosis; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hydrogen Peroxide; Male; Melatonin; Middle Aged; Oxidative Stress; Primary Cell Culture; Receptors, Melatonin; Retinal Pigment Epithelium; Tetrazolium Salts; Thiazoles; Tryptamines | 2012 |
In vitro antioxidant and antiproliferative potential of medicinal plants used in traditional Indian medicine to treat cancer.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; India; Magnoliopsida; MCF-7 Cells; Medicine, East Asian Traditional; Neoplasms; Nitric Oxide; Picrates; Plant Extracts; Tetrazolium Salts; Thiazoles | 2012 |
Hepatoprotective potential of astaxanthin against 2,3,7,8-tetrachlorodibenzo-p-dioxin in cultured rat hepatocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Cell Survival; Cells, Cultured; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Hepatocytes; L-Lactate Dehydrogenase; Liver; Male; Micronucleus Tests; Oxidative Stress; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Xanthophylls | 2014 |
Manganese accumulates within golgi apparatus in dopaminergic cells as revealed by synchrotron X-ray fluorescence nanoimaging.
Topics: Animals; Brefeldin A; Cell Survival; Dopaminergic Neurons; Endoplasmic Reticulum; Golgi Apparatus; Green Fluorescent Proteins; Homeostasis; Iron; Manganese; Neuroimaging; PC12 Cells; Protein Synthesis Inhibitors; Rats; Spectrometry, X-Ray Emission; Synchrotrons; Tetrazolium Salts; Thiazoles; Trace Elements | 2010 |
Generation of an adenovirus-parvovirus chimera with enhanced oncolytic potential.
Topics: Adenoviridae; Animals; Base Sequence; Cell Proliferation; Cell Survival; Cloning, Molecular; Fibroblasts; Gene Deletion; HEK293 Cells; HeLa Cells; Humans; Mice; Molecular Sequence Data; Oncolytic Viruses; Parvovirus; Promoter Regions, Genetic; Tetrazolium Salts; Thiazoles; Virology | 2012 |
Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.
Topics: Amphetamine; Analysis of Variance; Animals; Atorvastatin; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Malondialdehyde; Mitochondria; Motor Activity; NADH Dehydrogenase; Nitrites; Oxidopamine; Parkinsonian Disorders; Pyrroles; Rats; Rats, Wistar; Simvastatin; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
SOX9 gene plus heparinized TGF-β 3 coated dexamethasone loaded PLGA microspheres for inducement of chondrogenesis of hMSCs.
Topics: Animals; Cell Adhesion; Cell Survival; Chondrocytes; Dexamethasone; Female; Gene Expression Regulation; Glycosaminoglycans; Heparin; Humans; Lactic Acid; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; SOX9 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta3 | 2012 |
Osteogenesis induced by a bone forming peptide from the prodomain region of BMP-7.
Topics: Amino Acid Sequence; Biomarkers; Bone and Bones; Bone Morphogenetic Protein 7; Bone Regeneration; Calcium; CD47 Antigen; Cell Survival; Dose-Response Relationship, Drug; Humans; Hyaluronan Receptors; Integrin alphaV; Molecular Sequence Data; Osteogenesis; Osteoporosis; Peptide Fragments; Peptides; Protein Structure, Tertiary; Regeneration; Stem Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2012 |
Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: synthesis, characterization and in vitro cytotoxicity evaluation.
Topics: Annexin A5; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chitosan; DNA Fragmentation; DNA, Neoplasm; Drug Carriers; Drug Compounding; Drug Delivery Systems; Electrophoresis, Agar Gel; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Necrosis; Particle Size; Polyesters; Polymers; Tetrazolium Salts; Thiazoles | 2013 |
Particle-induced artifacts in the MTT and LDH viability assays.
Topics: Air Pollutants; Artifacts; Biological Assay; Cell Line; Cell Survival; Humans; L-Lactate Dehydrogenase; Nanoparticles; Particulate Matter; Sensitivity and Specificity; Soot; Tetrazolium Salts; Thiazoles; Titanium | 2012 |
The synergistic effect of beta-boswellic acid and Nurr1 overexpression on dopaminergic programming of antioxidant glutathione peroxidase-1-expressing murine embryonic stem cells.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Cell Differentiation; Chromatography, High Pressure Liquid; Dopamine; Dopaminergic Neurons; Embryonic Stem Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Immunohistochemistry; Induced Pluripotent Stem Cells; Lentivirus; Mice; Nuclear Receptor Subfamily 4, Group A, Member 2; Phenotype; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Triterpenes | 2012 |
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advanced; Glycine; Humans; Lactic Acid; Lactoylglutathione Lyase; Neutral Red; Oxidation-Reduction; Propidium; Pyruvaldehyde; Tetrazolium Salts; Thiazoles; Thiolester Hydrolases | 2012 |
The effect of titanium with electrochemical anodization on the response of the adherent osteoblast-like cell.
Topics: Acid Etching, Dental; Alkaline Phosphatase; Aluminum Oxide; Carbon Compounds, Inorganic; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Dental Etching; Dental Materials; Electrochemical Techniques; Humans; Hydrochloric Acid; Materials Testing; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanostructures; Osteoblasts; Photoelectron Spectroscopy; Silicon Compounds; Sulfuric Acids; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; Wettability | 2012 |
Pleurotus giganteus (Berk.) Karunarathna & K.D. Hyde: Nutritional value and in vitro neurite outgrowth activity in rat pheochromocytoma cells.
Topics: Animals; Biological Products; Dietary Carbohydrates; Dietary Fiber; Dose-Response Relationship, Drug; Fruiting Bodies, Fungal; Malaysia; MAP Kinase Signaling System; Nerve Growth Factor; Neurites; Neurodegenerative Diseases; Nutritive Value; Oncogene Protein v-akt; PC12 Cells; Phenols; Pheochromocytoma; Phosphatidylinositol 3-Kinases; Phytotherapy; Pleurotus; Potassium; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles; Triterpenes | 2012 |
Modulation of adenosine receptors by [60]fullerene hydrosoluble derivative in SK-N-MC cells.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Survival; Coloring Agents; DNA, Complementary; Fullerenes; Humans; Isomerism; Microscopy, Electron; Real-Time Polymerase Chain Reaction; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA; Solubility; Tetrazolium Salts; Thiazoles | 2011 |
Stronger and faster degradable biobased poly(propylene sebacate) as shape memory polymer by incorporating boehmite nanoplatelets.
Topics: Aluminum Hydroxide; Aluminum Oxide; Animals; Biocompatible Materials; Biodegradation, Environmental; Cell Survival; Humans; Materials Testing; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Molecular Weight; Nanostructures; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Temperature; Tensile Strength; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2012 |
MicroRNA155 in the growth and invasion of salivary adenoid cystic carcinoma.
Topics: Animals; Carcinoma, Adenoid Cystic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Coloring Agents; Disease Models, Animal; Electrophoretic Mobility Shift Assay; ErbB Receptors; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Neoplasm Invasiveness; NF-kappa B; Parotid Gland; Polymerase Chain Reaction; Salivary Gland Neoplasms; Tetrazolium Salts; Thiazoles; Transcription Factor RelA | 2013 |
Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product.
Topics: Animals; Cell Line; Cell Survival; Dextrans; Ethanol; Humans; Hydrogen-Ion Concentration; Immune System; Kinetics; Magnetic Resonance Spectroscopy; Mice; Microspheres; Models, Chemical; Particle Size; Polymers; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Vaccines | 2012 |
Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway.
Topics: Animals; Anticonvulsants; Antimetabolites; beta Catenin; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Female; Flow Cytometry; Glycogen Synthase Kinase 3; Immunohistochemistry; Megalencephaly; Neural Stem Cells; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Valproic Acid | 2012 |
Angiopoietin-1 preconditioning enhances survival and functional recovery of mesenchymal stem cell transplantation.
Topics: Angiopoietin-1; Animals; Apoptosis; Cell Survival; Chromones; Culture Media; Echocardiography; Enzyme Inhibitors; In Situ Nick-End Labeling; Mesenchymal Stem Cell Transplantation; Morpholines; Myocardial Infarction; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Transplantation Conditioning; Treatment Outcome | 2012 |
Comparative proteomic analysis of drug sodium iron chlorophyllin addition to Hep 3B cell line.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chlorophyllides; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Humans; Liver Neoplasms; Peroxiredoxins; Proteins; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles | 2012 |
Biological microdosimetry based on radiation cytotoxicity data.
Topics: Cell Nucleus; Cell Survival; Cells, Cultured; Cesium Radioisotopes; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Electromagnetic Radiation; Epithelial Cells; Gamma Rays; Humans; Models, Theoretical; Photons; Radiometry; Relative Biological Effectiveness; Stochastic Processes; Tetrazolium Salts; Thiazoles; X-Rays | 2013 |
Antifibrotic effects of quercetin in primary orbital fibroblasts and orbital fat tissue cultures of Graves' orbitopathy.
Topics: Actins; Adipose Tissue; Adult; Antioxidants; Biomarkers; Blotting, Western; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Fibronectins; Fibrosis; Graves Ophthalmopathy; Humans; L-Lactate Dehydrogenase; Male; Matrix Metalloproteinases; Middle Aged; Orbit; Orbital Diseases; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Wound Healing | 2012 |
Bmi-1 siRNA inhibited ovarian cancer cell line growth and decreased telomerase activity.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Primers; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Nuclear Proteins; Ovarian Neoplasms; Plasmids; Polycomb Repressive Complex 1; Proto-Oncogene Proteins; Repressor Proteins; RNA, Small Interfering; Telomerase; Tetrazolium Salts; Thiazoles | 2012 |
Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Benzenesulfonates; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dactinomycin; Homeostasis; Humans; Interleukin-1beta; Luminescent Measurements; Periodontal Ligament; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; Suramin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2013 |
Preparation, characterization and anti-angiogenesis activity of endostatin covalently modified by polysulfated heparin.
Topics: Amino Acids; Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Proliferation; Chick Embryo; Choroid; Circular Dichroism; Drug Stability; Electrophoresis, Polyacrylamide Gel; Endostatins; Eye Proteins; Heparin; Hot Temperature; Indicators and Reagents; Lasers; Neovascularization, Physiologic; Nerve Growth Factors; Serpins; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2012 |
Carnosic acid prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells via mediation of glutathione synthesis.
Topics: Abietanes; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Line; Down-Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidopamine; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
Reconstruction of tissue-engineered bone with bone marrow mesenchymal stem cells and partially deproteinized bone in vitro.
Topics: Animals; Bone and Bones; Bone Marrow Cells; Cell Adhesion; Cell Count; Cell Proliferation; Cells, Cultured; Culture Media, Conditioned; Mesenchymal Stem Cells; Osteogenesis; Primary Cell Culture; Rabbits; Swine; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2012 |
Identification of novel piperazinylquinoxaline derivatives as potent phosphoinositide 3-kinase (PI3K) inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Quinoxalines; Tetrazolium Salts; Thiazoles | 2012 |
Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability.
Topics: Adenosine Triphosphate; Aquaporins; Blotting, Western; Cell Survival; Cyclosporine; Hep G2 Cells; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria, Liver; Oxidants; Permeability; Reactive Oxygen Species; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Trypan Blue | 2012 |
The effects of 5-fluorouracil alone and in combination with 13-cis retinoic acid and vitamin D3 on human oral squamous cell carcinoma lines.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Combinations; Drug Synergism; Fluorouracil; Humans; In Situ Nick-End Labeling; Isotretinoin; Mouth Neoplasms; Tetrazolium Salts; Thiazoles | 2012 |
Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Leptin; Mice; Mitogen-Activated Protein Kinase 1; Neurons; Neuroprotective Agents; Organ Culture Techniques; Patch-Clamp Techniques; Peptide Fragments; Rats; Receptors, AMPA; Signal Transduction; STAT3 Transcription Factor; Synapses; Synaptic Potentials; tau Proteins; Tetrazolium Salts; Thiazoles | 2013 |
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Chymotrypsin; Citrate (si)-Synthase; Electron Transport Complex I; Female; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Neuroblastoma; Parkinson Disease; Plasma; Proteasome Endopeptidase Complex; RNA, Small Interfering; Statistics as Topic; Tetrazolium Salts; Thiazoles; Transfection; Ubiquitin; Ubiquitination; Up-Regulation | 2012 |
Two new triterpene saponins from Gynostemma pentaphyllum.
Topics: Antineoplastic Agents, Phytogenic; Dammaranes; Drugs, Chinese Herbal; Gynostemma; HL-60 Cells; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes | 2012 |
Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome.
Topics: Animals; Calcium-Binding Proteins; Cell Line, Tumor; Cell Movement; Disease Progression; DNA Primers; Extracellular Matrix Proteins; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunohistochemistry; Male; Mice; Mice, Mutant Strains; Microarray Analysis; Models, Biological; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rhoC GTP-Binding Protein; Tetrazolium Salts; Thiazoles | 2012 |
Acromyrmex octospinosus (Hymenoptera: Formicidae) management: effects of TRAMILs fungicidal plant extracts.
Topics: Alkaloids; Animals; Ants; Basidiomycota; Fungicides, Industrial; Inhibitory Concentration 50; Insect Control; Phenols; Plant Extracts; Symbiosis; Terpenes; Tetrazolium Salts; Thiazoles | 2012 |
Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis--an in vitro efficacy study.
Topics: Antineoplastic Agents, Phytogenic; Bone and Bones; Bone Marrow Cells; Cell Differentiation; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Endothelial Cells; Flavonoids; Humans; In Vitro Techniques; Neovascularization, Pathologic; Osteoblasts; Osteogenesis; Phenotype; Stem Cells; Tetrazolium Salts; Thiazoles | 2012 |
The heat shock protein 90 inhibitor 17-AAG suppresses growth and induces apoptosis in human cholangiocarcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholangiocarcinoma; Flow Cytometry; Formazans; Gene Expression Profiling; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cisplatin; Comet Assay; DNA Damage; Doxorubicin; Etoposide; Female; Histone Deacetylase 6; Histone Deacetylases; Humans; Immunoblotting; Immunohistochemistry; Inhibitory Concentration 50; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles | 2012 |
Preparation and characterization of polymeric nanoparticles for siRNA delivery to down-regulate the expressions of exogenous and endogenous target genes.
Topics: Cell Line, Tumor; Cell Survival; Coloring Agents; Down-Regulation; Drug Delivery Systems; Gene Expression; Gene Silencing; Gene Targeting; Gene Transfer Techniques; Humans; Nanoparticles; Plasmids; Polyesters; Polyethylene Glycols; Polymers; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2012 |
Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences.
Topics: beta-Galactosidase; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Computational Biology; Cyclin-Dependent Kinase Inhibitor p21; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Medicine, Ayurvedic; Models, Molecular; Molecular Structure; NF-E2-Related Factor 2; Plant Extracts; Plant Leaves; Tetrazolium Salts; Thiazoles; Triterpenes; Tumor Suppressor Protein p53; Withania; Withanolides | 2012 |
A new cytotoxic steroidal saponin from the rhizomes and roots of Smilax scobinicaulis.
Topics: Cell Line, Tumor; Cell Proliferation; Cytotoxins; Ethanol; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Extracts; Plant Roots; Rhizome; Saponins; Smilax; Steroids; Tetrazolium Salts; Thiazoles | 2013 |
N(1)-(quinolin-2-ylmethyl)butane-1,4-diamine, a polyamine analogue, attenuated injury in in vitro and in vivo models of cerebral ischemia.
Topics: Animals; Brain Ischemia; Calcium; Cells, Cultured; Cerebral Cortex; Coloring Agents; Glucose; Glutathione Peroxidase; Hypoxia; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nitric Oxide; PC12 Cells; Polyamines; Quinolines; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Peri-infarct flow transients predict outcome in rat focal brain ischemia.
Topics: Anesthesia; Anesthesia, Inhalation; Animals; Basal Ganglia; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Infarction; Cerebrovascular Circulation; Coloring Agents; Halothane; Hydrogen-Ion Concentration; Isoflurane; Laser-Doppler Flowmetry; Logistic Models; Male; Oxygen; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2012 |
Regulation of glycogen synthase kinase-3 beta (GSK-3β) by the Akt pathway in gliomas.
Topics: Blotting, Western; Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; ErbB Receptors; Gene Expression Regulation, Enzymologic; Glioma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lithium Chloride; Oncogene Protein v-akt; Phosphorylation; Tetrazolium Salts; Thiazoles; Wnt Proteins | 2012 |
Over-expression of human endosulfatase-1 exacerbates cadmium-induced injury to transformed human lung cells in vitro.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Cadmium; Cell Count; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Coloring Agents; Down-Regulation; Heparan Sulfate Proteoglycans; Humans; In Situ Nick-End Labeling; Lac Operon; Lung; Polymerase Chain Reaction; Respiratory Mucosa; Sulfotransferases; Tetrazolium Salts; Thiazoles; Transduction, Genetic; Up-Regulation | 2012 |
Exendin-4 improved rat cortical neuron survival under oxygen/glucose deprivation through PKA pathway.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Brain Ischemia; Cell Survival; Cerebral Cortex; Coloring Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum; Exenatide; Flow Cytometry; Fluorescent Antibody Technique; Glucagon-Like Peptide 1; Glucose; Hypoxia; Neurons; Neuroprotective Agents; PC12 Cells; Peptides; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles; Venoms | 2012 |
Recombinant human leptin induces growth inhibition and apoptosis in human gastric cancer MGC-803 cells.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Biological Products; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Flow Cytometry; Formazans; Gene Expression Profiling; Humans; Leptin; Reverse Transcriptase Polymerase Chain Reaction; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Colloidal formulations of etoposide based on poly(butyl cyanoacrylate) nanoparticles: preparation, physicochemical properties and cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzimidazoles; Cell Line, Tumor; Chemistry, Pharmaceutical; Colloids; Coloring Agents; Enbucrilate; Etoposide; Fluorescent Dyes; Humans; Indicators and Reagents; Light; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2013 |
Influence of TiN coating on the biocompatibility of medical NiTi alloy.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line; Cell Proliferation; Cell Survival; Coated Materials, Biocompatible; Coloring Agents; Flow Cytometry; Materials Testing; Mechanical Phenomena; Mice; Microscopy, Electron, Scanning; Nickel; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; X-Ray Diffraction | 2013 |
A nano complex of hydrophilic phthalocyanine and polyethylenimine for improved cellular internalization efficiency and phototoxicity.
Topics: Colorimetry; Coloring Agents; Dermatitis, Phototoxic; Drug Stability; Electrochemistry; Fluorescence; HeLa Cells; Humans; Indoles; Isoindoles; Light; Microscopy, Confocal; Microscopy, Fluorescence; Nanoparticles; Particle Size; Polyethyleneimine; Radiation-Sensitizing Agents; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2013 |
PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells.
Topics: Anti-Inflammatory Agents; Biomarkers; Brain Neoplasms; Carnosine; Cell Line, Tumor; Cell Survival; Coloring Agents; Down-Regulation; Fluorescent Antibody Technique; Glioblastoma; Humans; Isoquinolines; L-Lactate Dehydrogenase; Microscopy, Confocal; Nitrites; Phenanthrenes; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Tetrazolium Salts; Thiazoles; Trehalose | 2013 |
Cytotoxicity test of dentin bonding agents using millipore filters as dentin substitutes in a dentin barrier test.
Topics: Animals; Cattle; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Survival; Coloring Agents; Dentin; Dentin Permeability; Dentin-Bonding Agents; Diffusion Chambers, Culture; Fibroblasts; Materials Testing; Methacrylates; Mice; Micropore Filters; Nylons; Perfusion; Phenol; Resin Cements; Spectrophotometry; Surface Properties; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2013 |
DNA damage in human skin keratinocytes caused by multiwalled carbon nanotubes with carboxylate functionalization.
Topics: Cell Line; Comet Assay; DNA Damage; Humans; Keratinocytes; Nanotubes, Carbon; Oxidative Stress; Skin; Tetrazolium Salts; Thiazoles | 2014 |
The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells.
Topics: Animals; Blotting, Western; Carrier Proteins; Cell Proliferation; Electrophoresis, Polyacrylamide Gel; Endosomal Sorting Complexes Required for Transport; Exosomes; HEK293 Cells; Humans; Immunohistochemistry; Immunoprecipitation; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron; Nedd4 Ubiquitin Protein Ligases; Oncogene Protein v-akt; Phosphorylation; PTEN Phosphohydrolase; Tetrazolium Salts; Thiazoles; Trypan Blue; Ubiquitin-Protein Ligases | 2012 |
Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blotting, Western; Cell Survival; Cells, Cultured; Chromans; Congo Red; Female; Free Radical Scavengers; Mutation; Neurons; Neurotoxins; Oxidative Stress; Peptide Fragments; Pregnancy; Protein Conformation; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Vitamin E | 2012 |
The effects of silver nanoparticles and doxorubicin combination on DNA structure and its antiproliferative effect against T47D and MCF7 cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Circular Dichroism; DNA; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Kinetics; Metal Nanoparticles; Microscopy, Fluorescence; Nucleic Acid Conformation; Silver; Stem Cells; Tetrazolium Salts; Thermodynamics; Thiazoles | 2012 |
Phospholipase D participates in H(2)O(2)-induced A549 alveolar epithelial cell migration.
Topics: 1-Butanol; Alveolar Epithelial Cells; Antioxidants; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Antagonism; Humans; Hydrogen Peroxide; Lung Neoplasms; Oxidants; Phosphatidic Acids; Phospholipase D; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Trojan-horse nanotube on-command intracellular drug delivery.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Ceramides; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Materials Testing; Nanomedicine; Nanotechnology; Nanotubes; Paclitaxel; Pancreatic Neoplasms; RNA, Small Interfering; Solubility; Tetrazolium Salts; Thiazoles | 2012 |
Hemocyte responses of Dreissena polymorpha following a short-term in vivo exposure to titanium dioxide nanoparticles: preliminary investigations.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Dreissena; France; Hemocytes; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinases; Nanoparticles; Phagocytosis; Phosphorylation; Tetrazolium Salts; Thiazoles; Titanium; X-Ray Diffraction | 2012 |
Phycocyanin may suppress D-galactose-induced human lens epithelial cell apoptosis through mitochondrial and unfolded protein response pathways.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Cell Survival; Cells, Cultured; DNA Fragmentation; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Epithelial Cells; Galactose; Humans; Lens, Crystalline; Microscopy, Fluorescence; Mitochondria; Phycocyanin; Tetrazolium Salts; Thiazoles; Unfolded Protein Response | 2012 |
Effect of polymer degree of conversion on Streptococcus mutans biofilms.
Topics: Analysis of Variance; Biofilms; Cell Culture Techniques; Magnetic Resonance Spectroscopy; Methacrylates; Polymerization; Spectrophotometry, Ultraviolet; Streptococcus mutans; Surface Properties; Tetrazolium Salts; Thiazoles | 2012 |
Melatonin modulates apoptosis and TRPM2 channels in transfected cells activated by oxidative stress.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Boron Compounds; Calcium; CHO Cells; Clusterin; Cricetinae; Dose-Response Relationship, Drug; Electric Stimulation; Hydrogen Peroxide; Melatonin; Membrane Potentials; Oxidants; Oxidative Stress; Patch-Clamp Techniques; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2012 |
Further evidence for the anti-inflammatory activity of oleocanthal: inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes.
Topics: Aldehydes; Analysis of Variance; Animals; Anti-Inflammatory Agents; Benzothiazoles; Blotting, Western; Chemokine CCL3; Chondrocytes; Cyclopentane Monoterpenes; Diamines; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Interleukin-6; Macrophages; Mice; Molecular Structure; Organic Chemicals; Phenols; Quinolines; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2012 |
Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons.
Topics: Amygdala; Animals; Biotinylation; Brain; Cell Death; Cell Survival; Cerebral Cortex; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Membrane Proteins; Mitochondria; Models, Biological; Neurons; Nimodipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Surface Properties; Tetrazolium Salts; Thiazoles; Zinc | 2012 |
A covalently crosslinked polysaccharide hydrogel for potential applications in drug delivery and tissue engineering.
Topics: Alginates; Animals; Cattle; Chitosan; Cross-Linking Reagents; Diffusion; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; Hydrogels; Mice; Microscopy, Electron, Scanning; NIH 3T3 Cells; Polysaccharides; Serum Albumin, Bovine; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2012 |
Effect of annexin A2 on hepatopulmonary syndrome rat serum-induced proliferation of pulmonary arterial smooth muscle cells.
Topics: Animals; Annexin A2; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hepatopulmonary Syndrome; Male; MAP Kinase Signaling System; Muscle, Smooth; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Serum; Signal Transduction; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Thymidine; Transfection | 2013 |
A new triterpenoid from Verbena officinalis L.
Topics: Cell Line, Tumor; Cell Proliferation; China; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Extracts; Plant Leaves; Tetrazolium Salts; Thiazoles; Triterpenes; Verbena | 2013 |
Alteration in glutathione content and associated enzyme activities in the synaptic terminals but not in the non-synaptic mitochondria from the frontal cortex of Parkinson's disease brains.
Topics: Adult; Aged; Biomarkers; Blotting, Western; Citrate (si)-Synthase; Coloring Agents; Electrophoresis, Polyacrylamide Gel; Female; Frontal Lobe; Glutathione; Glutathione Reductase; Glutathione Transferase; Humans; Immunohistochemistry; Malate Dehydrogenase; Male; Middle Aged; Mitochondria; Neuropil; Nitrates; Oxidants; Parkinson Disease, Secondary; Presynaptic Terminals; Protein Carbonylation; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2013 |
MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; DNA Primers; Electrophoretic Mobility Shift Assay; Growth Hormone; Immunoprecipitation; Janus Kinase 2; Luciferases; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Sulfones; Tetrazolium Salts; Thiazoles | 2012 |
Suppressive effect of PARP-1 inhibitor on JC virus replication in vitro.
Topics: Antiviral Agents; Benzamides; Cell Line; Cell Survival; Enzyme Inhibitors; Humans; JC Virus; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Staining and Labeling; Tetrazolium Salts; Thiazoles; Viral Load; Virus Replication | 2013 |
Initial attachment, subsequent cell proliferation/viability and gene expression of epithelial cells related to attachment and wound healing in response to different titanium surfaces.
Topics: Acid Etching, Dental; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Coloring Agents; Dental Etching; Dental Implants; Dental Materials; Epithelial Cells; Gene Expression Regulation; Humans; Hydrophobic and Hydrophilic Interactions; Integrin alpha6; Integrin beta4; Keratin-14; Membrane Proteins; Mouth Mucosa; Mouth Neoplasms; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; Transforming Growth Factor beta; Vinculin; Wound Healing | 2012 |
Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells.
Topics: Adaptation, Physiological; Alcohol Oxidoreductases; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Blotting, Western; Cell Line, Tumor; Coloring Agents; Enzyme Induction; Humans; Hydroquinones; Inactivation, Metabolic; Nerve Tissue Proteins; Pyruvaldehyde; RNA Interference; Tetrazolium Salts; Thiazoles | 2013 |
Interleukin-1β inhibits the differentiation of hippocampal neural precursor cells into serotonergic neurons.
Topics: Animals; Animals, Newborn; Cell Count; Cell Differentiation; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Hippocampus; Interleukin-1beta; Neural Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Serotonergic Neurons; Serotonin; Tetrazolium Salts; Thiazoles | 2013 |
Knockdown of MMP-7 inhibits cell proliferation and enhances sensitivity to 5-Fluorouracil and X-ray irradiation in colon cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Epithelial Cells; Flow Cytometry; Fluorouracil; Gene Knockdown Techniques; Humans; Matrix Metalloproteinase 7; Staining and Labeling; Tetrazolium Salts; Thiazoles; X-Rays | 2014 |
Interaction of 5-amino-1,3,4-thiadiazole-2-thiol and its violuric acid adduct with Pt(II) - crystals structures, spectroscopic properties and cytotoxic activity.
Topics: Antineoplastic Agents; Barbiturates; Cell Line, Tumor; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Humans; Hydrogen Bonding; Indicators and Reagents; Models, Molecular; Molecular Conformation; Platinum; Spectrophotometry, Infrared; Tetrazolium Salts; Thiadiazoles; Thiazoles; X-Ray Diffraction | 2012 |
Nelfinavir is effective in inhibiting the multiplication and aspartic peptidase activity of Leishmania species, including strains obtained from HIV-positive patients.
Topics: Antiprotozoal Agents; Aspartic Acid Proteases; Colorimetry; Fluorometry; HIV Infections; Humans; Leishmania; Leishmaniasis; Microbial Viability; Nelfinavir; Oligopeptides; Saquinavir; Tetrazolium Salts; Thiazoles | 2013 |
Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation.
Topics: Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Polarity; Cell Proliferation; Collagen; Cytoskeletal Proteins; Drug Combinations; Epithelial Cells; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Image Processing, Computer-Assisted; Laminin; Mammary Glands, Human; Microscopy, Fluorescence; Proteoglycans; Tetrazolium Salts; Thiazoles | 2012 |
CaMKKβ is involved in AMP-activated protein kinase activation by baicalin in LKB1 deficient cell lines.
Topics: Acetyl-CoA Carboxylase; Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Benzimidazoles; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Energy Metabolism; Enzyme Activation; Flavonoids; HeLa Cells; Humans; Luciferases; Naphthalimides; Phosphorylation; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles | 2012 |
Neuroprotective action and free radical scavenging activity of Guttiferone-A, a naturally occurring prenylated benzophenone.
Topics: Animals; Benzophenones; Biphenyl Compounds; Cell Survival; Cerebral Cortex; Coloring Agents; Electrochemistry; Free Radical Scavengers; Fruit; Garcinia; Glutamic Acid; Humans; Hydrogen Peroxide; Iron; Lipid Peroxidation; Neurons; Neuroprotective Agents; PC12 Cells; Picrates; Prenylation; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways.
Topics: Animals; Antimalarials; Artemisinins; Blotting, Western; Cell Survival; Coloring Agents; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Data Interpretation, Statistical; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Neurites; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
In vitro and in vivo investigation of the biological and mechanical behaviour of resin-modified glass-ionomer cement containing chlorhexidine.
Topics: Actinomyces; Anti-Infective Agents, Local; Cell Culture Techniques; Cell Line; Cell Shape; Cell Survival; Child; Child, Preschool; Chlorhexidine; Coloring Agents; Compressive Strength; Dental Caries; Dental Cavity Lining; Dentin; Glass Ionomer Cements; Humans; Lactobacillus acidophilus; Materials Testing; Mechanical Phenomena; Microbial Viability; Microscopy, Electron, Scanning; Odontoblasts; Resin Cements; Streptococcus mutans; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
N-isopropylacrylamide-modified polyethylenimines as effective gene carriers.
Topics: Acrylamides; DNA; Electrophoretic Mobility Shift Assay; Endocytosis; Flow Cytometry; Gene Transfer Techniques; Genetic Therapy; HeLa Cells; Humans; Microscopy, Confocal; Molecular Structure; Particle Size; Plasmids; Polyethyleneimine; Tetrazolium Salts; Thiazoles | 2012 |
Psoriasis is associated with low serum levels of hydrogen sulfide, a potential anti-inflammatory molecule.
Topics: Anti-Inflammatory Agents; Blotting, Western; Cell Line; DNA Primers; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydrogen Sulfide; Interleukin-6; Interleukin-8; Keratinocytes; Nitric Oxide; Nitrites; Psoriasis; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
2-Hydroxyoleic acid induces ER stress and autophagy in various human glioma cell lines.
Topics: Antineoplastic Agents; Autophagy; Brain Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Fatty Acids; Fibroblasts; Glioma; Humans; Lung; Oleic Acids; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
A peptide binding to the β-site of APP improves spatial memory and attenuates Aβ burden in Alzheimer's disease transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzothiazoles; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Maze Learning; Memory; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Peptide Library; Peptides; Protein Binding; Protein Structure, Tertiary; Sequence Analysis, DNA; Spatial Behavior; Tetrazolium Salts; Thiazoles | 2012 |
Factors related to unstained areas in whole ewe ovaries perfused with a metabolic marker.
Topics: Animals; Biomarkers; Cryopreservation; Female; Fertility Preservation; Logistic Models; Multivariate Analysis; Ovary; Perfusion; Sheep; Staining and Labeling; Tetrazolium Salts; Thiazoles; Tissue Preservation | 2013 |
Macrophage migration inhibitory factor (MIF) enhances palmitic acid- and glucose-induced murine beta cell dysfunction and destruction in vitro.
Topics: Animals; Apoptosis; Caspase 3; Cell Line; Cytokines; Diabetes Mellitus, Type 2; DNA Fragmentation; Gene Expression Profiling; Glucose; In Vitro Techniques; Insulin-Secreting Cells; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Palmitic Acid; Tetrazolium Salts; Thiazoles | 2012 |
Genotoxic effects of copper oxide nanoparticles in Neuro 2A cell cultures.
Topics: Animals; Cell Line; Cell Survival; Copper; Cytochalasin B; DNA Damage; DNA Fragmentation; DNA Methylation; Lipid Peroxidation; Metal Nanoparticles; Mice; Micronucleus Tests; Mitochondria; Tetrazolium Salts; Thiazoles | 2012 |
Hepatoprotective and cytoprotective properties of Hyptis suaveolens against oxidative stress-induced damage by CCl(4) and H(2)O(2).
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatocytes; Histocytochemistry; Humans; Hydrogen Peroxide; Hyptis; Liver; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2012 |
Influence of Ginkgo biloba extract on the proliferation, apoptosis of ACC-2 cell and Survivin gene expression in adenoid cystic carcinoma of lacrimal gland.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Survival; Flow Cytometry; Gene Expression; Ginkgo biloba; Humans; Inhibitor of Apoptosis Proteins; Lacrimal Apparatus; Plant Extracts; Staining and Labeling; Survivin; Tetrazolium Salts; Thiazoles | 2012 |
Dietary β-carotene regulates interleukin-1β-induced expression of apolipoprotein E in astrocytes isolated from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Apolipoproteins E; Astrocytes; beta Carotene; Blotting, Western; Cell Hypoxia; Cell Survival; Cholesterol; Coloring Agents; Diet; Fibroblast Growth Factor 1; Fluorescent Antibody Technique; Gene Expression; Interleukin-1beta; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 1; Species Specificity; Stroke; Tetrazolium Salts; Thiazoles | 2013 |
Evaluation of in vitro antioxidant potency of exopolysaccharide from endophytic Fusarium solani SD5.
Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Cell Survival; Cells, Cultured; Endophytes; Free Radical Scavengers; Free Radicals; Fungal Polysaccharides; Fusarium; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Macrophages, Peritoneal; Male; Malondialdehyde; Mice; Picrates; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2013 |
p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity.
Topics: 1-Methyl-4-phenylpyridinium; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Cycle Proteins; Cell Survival; Chlorocebus aethiops; Chromobox Protein Homolog 5; COS Cells; Cyclin-Dependent Kinase 5; Immunohistochemistry; Microscopy, Fluorescence; Nerve Tissue Proteins; Neurons; Peptide Fragments; Peptides; Peroxiredoxins; Phosphorylation; Proteolysis; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2012 |
Adaptation of stem cells to 96-well plate assays: use of human embryonic and mouse neural stem cells in the MTT assay.
Topics: Animals; Cell Count; Embryonic Stem Cells; Humans; Mice; Neural Stem Cells; Spectrophotometry; Stem Cell Transplantation; Stem Cells; Tetrazolium Salts; Thiazoles | 2012 |
HPLC analysis and cytotoxic activity of Vernonia cinerea.
Topics: Antineoplastic Agents, Phytogenic; Cambodia; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methanol; Methylene Chloride; Sesquiterpenes; Solvents; Tetrazolium Salts; Thiazoles; Vernonia; Water | 2012 |
Two new naphthoquinone derivatives from the stem bark of Callicarpa maingayi.
Topics: Antineoplastic Agents, Phytogenic; Callicarpa; Chloroform; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Naphthoquinones; Plant Bark; Plant Extracts; Plant Stems; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2012 |
Novel sorbicillin analogues from the marine fungus Trichoderma sp. associated with the seastar Acanthaster planci.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Chromans; Circular Dichroism; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Starfish; Tetrazolium Salts; Thiazoles; Trichoderma | 2012 |
HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.
Topics: Cell Dedifferentiation; Chromatin Immunoprecipitation; DNA Primers; Embryonic Stem Cells; Gene Expression Regulation; Gene Regulatory Networks; HMGA1a Protein; Humans; Kruppel-Like Factor 4; Pluripotent Stem Cells; Promoter Regions, Genetic; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles; Transcription Factors; Transduction, Genetic | 2012 |
Toxicity evaluation of individual and mixed enniatins using an in vitro method with CHO-K1 cells.
Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Depsipeptides; Mycotoxins; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2013 |
Setting a colorimetric assay with MTT for assessment of trichomonicidal activity.
Topics: Antitrichomonal Agents; Colorimetry; Culture Media; Female; Humans; Metronidazole; Parasitic Sensitivity Tests; Tetrazolium Salts; Thiazoles; Trichomonas Infections; Trichomonas vaginalis | 2014 |
Analysis of the transport of and cytotoxic effects for nalbuphine solution in corneal cells.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Cells, Cultured; Corneal Stroma; Dogs; Epithelium, Corneal; Eye Enucleation; Fibroblasts; Humans; Nalbuphine; Tetrazolium Salts; Thiazoles; Wound Healing | 2012 |
Interest of designed cyclodextrin-tools in gene delivery.
Topics: Carbohydrate Sequence; Coloring Agents; Cyclodextrins; DNA; Drug Carriers; Drug Delivery Systems; Gene Transfer Techniques; Models, Molecular; Molecular Sequence Data; Tetrazolium Salts; Thiazoles | 2012 |
Impregnation of silver sulfadiazine into bacterial cellulose for antimicrobial and biocompatible wound dressing.
Topics: Animals; Anti-Infective Agents; Bandages; Biocompatible Materials; Cell Proliferation; Cellulose; Epidermis; Escherichia coli; Hydrogen-Ion Concentration; Materials Testing; Microbial Sensitivity Tests; Microscopy; Microscopy, Electron, Scanning; Pseudomonas aeruginosa; Rats; Silver Sulfadiazine; Staphylococcus aureus; Tetrazolium Salts; Thiazoles; Time Factors; Wound Healing; X-Ray Diffraction | 2012 |
The CREB-miR-9 negative feedback minicircuitry coordinates the migration and proliferation of glioma cells.
Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation, Neoplastic; Glioma; Glucose; HeLa Cells; Humans; MicroRNAs; Neurofibromin 1; Tetrazolium Salts; Thiazoles; Transfection; Wound Healing | 2012 |
Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, Liquid; Collagen; Colon; Comet Assay; Digestion; Drug Combinations; Fermentation; Fruit; Gallic Acid; Gastrointestinal Tract; Humans; Laminin; Mass Spectrometry; Mutation; Phenol; Plant Extracts; Proteoglycans; Tetrazolium Salts; Thiazoles | 2012 |
Cell-mediated degradation of strontium-doped calcium polyphosphate scaffold for bone tissue engineering.
Topics: Animals; Biocompatible Materials; Bone and Bones; Bone Substitutes; Calcium; Calcium Phosphates; Cell Line; Inflammation; Macrophages; Mice; Microscopy, Electron, Scanning; Monocytes; Osteoblasts; Osteoclasts; Phosphates; Polyphosphates; Rabbits; Strontium; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2012 |
A novel root-end filling material based on hydroxyapatite, tetracalcium phosphate and polyacrylic acid.
Topics: Acrylic Resins; Animals; Calcium Phosphates; Cell Culture Techniques; Cell Line; Cell Survival; Citrates; Citric Acid; Coloring Agents; Compressive Strength; Dental Cements; Durapatite; Fibroblasts; Gentian Violet; Glass Ionomer Cements; Hydrogen-Ion Concentration; Materials Testing; Mice; Root Canal Filling Materials; Sodium Citrate; Solubility; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors; X-Ray Diffraction | 2013 |
Cytosolic protection against ultraviolet induced DNA damage by blueberry anthocyanins and anthocyanidins in hepatocarcinoma HepG2 cells.
Topics: Anthocyanins; Blueberry Plants; Cell Survival; Comet Assay; DNA Damage; Gene Expression Profiling; Hep G2 Cells; Humans; Radiation-Protective Agents; Reactive Oxygen Species; Staining and Labeling; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2013 |
Overexpression of human Argonaute2 inhibits cell and tumor growth.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Argonaute Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Nude; MicroRNAs; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.
Topics: Animals; Animals, Newborn; Cardiomegaly; Coloring Agents; Echocardiography; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Immunohistochemistry; Leucine; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NFATC Transcription Factors; Nicotinamide Phosphoribosyltransferase; Rats; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Ventricular Remodeling | 2013 |
Evaluation of the cytotoxicity of different root canal sealers on L929 cell line by MTT assay.
Topics: Animals; Cell Survival; Fibroblasts; L Cells; Mice; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Zinc Oxide-Eugenol Cement | 2012 |
Influence of thicknesses of smear layer on the transdentinal cytotoxicity and bond strength of a resin-modified glass-ionomer cement.
Topics: Cell Culture Techniques; Cell Line; Cell Shape; Cell Survival; Coloring Agents; Curing Lights, Dental; Dental Bonding; Dental Pulp; Dental Stress Analysis; Dentin; Dentin Permeability; Glass Ionomer Cements; Humans; Light-Curing of Dental Adhesives; Microscopy, Electron, Scanning; Resin Cements; Shear Strength; Smear Layer; Stress, Mechanical; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2012 |
Novel wound dressing based on nanofibrous PHBV-keratin mats.
Topics: Animals; Bandages; Electrophoresis, Polyacrylamide Gel; Keratins; Mice; Mice, Nude; Microscopy, Atomic Force; Nanofibers; NIH 3T3 Cells; Polyesters; Spectrum Analysis, Raman; Tetrazolium Salts; Thiazoles; Wound Healing | 2015 |
Photocrosslinked alginate with hyaluronic acid hydrogels as vehicles for mesenchymal stem cell encapsulation and chondrogenesis.
Topics: Alginates; Animals; Bone Marrow Cells; Cell Differentiation; Cell Survival; Cells, Cultured; Chondrocytes; Chondrogenesis; Cross-Linking Reagents; Dogs; Fluorescent Dyes; Genetic Markers; Hyaluronic Acid; Hydrogels; Magnetic Resonance Spectroscopy; Mesenchymal Stem Cell Transplantation; Pharmaceutical Vehicles; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Camphorquinone inhibits odontogenic differentiation of dental pulp cells and triggers release of inflammatory cytokines.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Anthraquinones; Blotting, Western; Camphor; Cell Differentiation; Cell Survival; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Dental Materials; Dental Pulp; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Materials Testing; Matrix Metalloproteinase 3; Methacrylates; Mice; Odontogenesis; Photoinitiators, Dental; Tetrazolium Salts; Thiazoles; Tooth Calcification; Tumor Suppressor Protein p53 | 2013 |
The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity.
Topics: Animals; Animals, Newborn; Brain; Caveolin 1; Cell Survival; Chemokine CXCL2; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; L-Lactate Dehydrogenase; Lipopolysaccharides; Membrane Microdomains; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neurons; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Delivery of short interfering ribonucleic acid-complexed magnetic nanoparticles in an oscillating field occurs via caveolae-mediated endocytosis.
Topics: Animals; Caveolae; Endocytosis; Flow Cytometry; Gene Transfer Techniques; Green Fluorescent Proteins; HeLa Cells; Humans; Magnetic Fields; Magnetite Nanoparticles; Rats; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2012 |
Assessment of Spirulina-PCL nanofiber for the regeneration of dermal fibroblast layers.
Topics: Animals; Cell Culture Techniques; Dermis; Fibroblasts; Humans; Mice; Microscopy, Electron, Scanning; Nanofibers; Oxidative Stress; Polyesters; Rats; Reactive Oxygen Species; Regeneration; Spirulina; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2013 |
Effects of mercury on the steroidogenesis of human adrenocarcinoma (NCI-H295R) cell line.
Topics: Adrenal Glands; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Gonads; Humans; Mercuric Chloride; Progesterone; Spectrophotometry; Testosterone; Tetrazolium Salts; Thiazoles | 2013 |
Evaluation of the effects of transient or continuous PTH administration to odontoblast-like cells.
Topics: Alkaline Phosphatase; Animals; Anthraquinones; Biglycan; Calcification, Physiologic; Cell Culture Techniques; Cell Line; Cell Survival; Collagen Type I; Colorimetry; Coloring Agents; Drug Administration Schedule; Extracellular Matrix Proteins; Matrix Metalloproteinase 2; Mice; Odontoblasts; Parathyroid Hormone; Phosphoproteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Tetrazolium Salts; Thiazoles | 2013 |
Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone.
Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Cytokines; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Glioma; Glutathione; Haloperidol; Hippocampus; Immunohistochemistry; Interleukin-1beta; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Nerve Growth Factors; Neuroglia; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Risperidone; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2013 |
Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.
Topics: Animal Feed; Animals; Cell Line, Tumor; Cell Survival; Diet; Humans; Immunohistochemistry; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Multiprotein Complexes; Mutation; Phosphorylation; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Resveratrol; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors; TOR Serine-Threonine Kinases | 2013 |
Caffeine alters mitochondrial dehydrogenase and alkaline phosphatase activity of human gingival fibroblasts in vitro.
Topics: Alkaline Phosphatase; Caffeine; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Shape; Cell Survival; Central Nervous System Stimulants; Coloring Agents; Fibroblasts; Gingiva; Humans; Mitochondria; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
Comparison of proliferative capacity of genetically-engineered pig and human corneal endothelial cells.
Topics: Adult; Animals; Animals, Genetically Modified; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Endothelial Cells; Endothelium, Corneal; Female; Humans; Male; Middle Aged; Swine; Tetrazolium Salts; Thiazoles | 2013 |
L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the 'collusion' hypothesis for increased extracellular L-glutamate concentration in neuroinflammation.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Benzopyrans; Carbenoxolone; Cell Death; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Transporter 1; Extracellular Fluid; Gene Expression Regulation; Glutamic Acid; L-Lactate Dehydrogenase; Lipopolysaccharides; Microglia; Neurons; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2012 |
Novel SN38 conjugate-forming nanoparticles as anticancer prodrug: in vitro and in vivo studies.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Micelles; Nanoparticles; Prodrugs; Solubility; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2013 |
The MTT assay is a rapid and reliable quantitative method to assess Staphylococcus aureus induced endothelial cell damage.
Topics: Cell Survival; Cells, Cultured; Chromium Radioisotopes; Cytological Techniques; Endothelial Cells; Humans; Staining and Labeling; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2013 |
Novel dental adhesive containing antibacterial agents and calcium phosphate nanoparticles.
Topics: Ammonium Compounds; Anti-Bacterial Agents; Biofilms; Calcium Phosphates; Cell Survival; Dental Caries; Dental Cements; Dentin; Humans; Lactic Acid; Metal Nanoparticles; Methacrylates; Microscopy, Electron, Transmission; Saliva; Silver; Stem Cells; Tetrazolium Salts; Thiazoles | 2013 |
Basal splicing factors regulate the stability of mature mRNAs in trypanosomes.
Topics: Animals; DNA-Binding Proteins; Gene Expression; Leishmania; Models, Genetic; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Poly A; Ribonucleoproteins; RNA Interference; RNA Splicing; RNA Splicing Factors; RNA-Binding Proteins; RNA, Messenger; Splicing Factor U2AF; Tetrazolium Salts; Thiazoles; Trans-Splicing; Transcription Factors; Transcription, Genetic; Trypanosoma brucei brucei | 2013 |
Observations on the viability of C6-glioma cells after sonoporation with low-intensity ultrasound and microbubbles.
Topics: Acridine Orange; Animals; Annexin A5; Carbocyanines; Cell Line, Tumor; Cell Membrane; Cell Survival; Fluoresceins; Fluorescent Dyes; Glioma; Microbubbles; Microscopy, Fluorescence; Rats; Sonication; Tetrazolium Salts; Thiazoles | 2013 |
Screening for cytotoxic activity of ovotransferrin and its enzyme hydrolysates.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chickens; Conalbumin; DNA Damage; Dose-Response Relationship, Drug; Egg White; Humans; Tetrazolium Salts; Thiazoles | 2013 |
Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity.
Topics: Agar; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Chemotaxis; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B p52 Subunit; NF-kappaB-Inducing Kinase; Pancreatic Neoplasms; Proteasome Endopeptidase Complex; Protein Binding; Protein Serine-Threonine Kinases; Tetrazolium Salts; Thiazoles; TNF Receptor-Associated Factor 2 | 2013 |
Characterization and cellular interaction of fluorescent-labeled PHEMA nanoparticles.
Topics: Acridine Orange; Animals; Cell Line; Cell Survival; Drug Carriers; Emulsions; Fibroblasts; Fluorescent Dyes; Mice; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyhydroxyethyl Methacrylate; Polymerization; Spectroscopy, Fourier Transform Infrared; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Enzyme based cleavage strategy of Bacillus lentus BI377 in response to metabolism of azoic recalcitrant.
Topics: Animals; Bacillus; Cell Line; Coloring Agents; Mice; Naphthalenesulfonates; Spectrophotometry; Tetrazolium Salts; Thiazoles; Triazines; Water Pollutants, Chemical | 2013 |
The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor.
Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Imidazoles; Lung Neoplasms; Mice; Mice, SCID; Mutation; Neoplasm Transplantation; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines; Quinolines; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Treatment Outcome | 2013 |
Usefulness of controlled release of growth factors in investigating the early events of dentin-pulp regeneration.
Topics: Adolescent; Antigens, Surface; Cell Culture Techniques; Cell Migration Assays; Cell Movement; Cell Proliferation; Cell Survival; Chemotactic Factors; Coloring Agents; Delayed-Action Preparations; Dental Pulp; Dentin; Diffusion Chambers, Culture; Drug Carriers; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Regeneration; Stem Cells; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2013 |
Evaluation of cytotoxicity and physicochemical properties of calcium silicate-based endodontic sealer MTA Fillapex.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Calcium Compounds; Cell Survival; Chemical Phenomena; Coloring Agents; Contrast Media; Drug Combinations; Epoxy Resins; Fibroblasts; Hydrogen-Ion Concentration; Materials Testing; Mice; Mice, Inbred BALB C; Oxides; Rheology; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
Expression and clinical relevance of MET and ALK in Ewing sarcomas.
Topics: Adolescent; Adult; Anaplastic Lymphoma Kinase; Anilides; Child; Child, Preschool; Chromosome Aberrations; Crizotinib; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Inhibitory Concentration 50; Male; Middle Aged; Neoplasm Metastasis; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Receptor Protein-Tyrosine Kinases; Recurrence; Sarcoma, Ewing; Tetrazolium Salts; Thiazoles; Treatment Outcome; Young Adult | 2013 |
Biological characteristics of adult degenerative nucleus pulposus cells in a three-dimensional microcarrier stirring culture system.
Topics: Adult; Aged; Bioreactors; Cell Culture Techniques; Cell Cycle; Collagen Type I; Collagen Type II; Extracellular Matrix; Female; Flow Cytometry; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Male; Middle Aged; Proteoglycans; Sulfur Radioisotopes; Tetrazolium Salts; Thiazoles; Thymidine; Tritium; Young Adult | 2013 |
Fluoride modulates preosteoblasts viability and matrix metalloproteinases-2 and -9 activities.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Carbon Dioxide; Cariostatic Agents; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cell Survival; Colorimetry; Coloring Agents; Culture Media; Dose-Response Relationship, Drug; Extracellular Matrix; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Osteoblasts; Sodium Fluoride; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Reduced toxicity and superior cellular response of preosteoblasts to Ti-6Al-7Nb alloy and comparison with Ti-6Al-4V.
Topics: 3T3 Cells; Actins; Alloys; Animals; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cell Survival; Coloring Agents; Fibronectins; Fluorescent Antibody Technique; Materials Testing; Mice; Microscopy, Electron, Scanning; Osteoblasts; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium; Vinculin | 2013 |
Fabrication of FITC-doped silica nanoparticles and study of their cellular uptake in the presence of lectins.
Topics: Carbohydrates; Cell Line; Cell Survival; Electrochemistry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Galactose; Hepatocytes; Humans; Light; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles; Ricin; Scattering, Radiation; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thermogravimetry; Thiazoles | 2013 |
S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway.
Topics: Animals; Calgranulin B; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Random Allocation; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2013 |
Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Pancreatic Ducts; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Bombesin; Cell Line; Cell Proliferation; Cell Size; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gastrin-Releasing Peptide; Gene Expression Profiling; Humans; Male; NF-kappa B; Peptide Fragments; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Hyperplasia; Rats; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Testosterone; Tetrazolium Salts; Thiazoles | 2013 |
New alkylated benzoquinone from Iris nepalensis.
Topics: Benzoquinones; Cell Line, Tumor; Chloroform; Humans; India; Inhibitory Concentration 50; Iris Plant; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Rhizome; Tetrazolium Salts; Thiazoles | 2013 |
Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Desert Climate; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases.
Topics: Animals; Animals, Newborn; Annexin A5; Antioxidants; Blotting, Western; Brain; Cell Survival; Coloring Agents; Fluorescent Dyes; In Vitro Techniques; L-Lactate Dehydrogenase; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2013 |
A Serum-Resistant Low-Generation Polyamidoamine with PEI 423 Outer Layer for Gene Delivery Vector.
Topics: Dendrimers; Electrophoresis, Agar Gel; Gene Transfer Techniques; Genetic Engineering; Genetic Vectors; Green Fluorescent Proteins; HEK293 Cells; Humans; Macromolecular Substances; Microscopy, Atomic Force; Microscopy, Confocal; Models, Molecular; Particle Size; Polyamines; Tetrazolium Salts; Thiazoles | 2013 |
The brominated compound aeroplysinin-1 inhibits proliferation and the expression of key pro- inflammatory molecules in human endothelial and monocyte cells.
Topics: Acetonitriles; Angiogenesis Inhibitors; Animals; Cell Proliferation; Chemokine CCL2; Cyclohexenes; Cyclooxygenase 2 Inhibitors; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Monocytes; Porifera; Tetrazolium Salts; Thiazoles; Thrombospondin 1 | 2013 |
Targeted delivery of immunotoxin by antibody to ganglioside GD3: a novel drug delivery route for tumor cells.
Topics: Animals; Antibodies; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Delivery Systems; Endosomes; Gangliosides; Humans; Immunotoxins; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Ribosome Inactivating Proteins, Type 1; Saporins; Tetrazolium Salts; Thiazoles | 2013 |
Reductase-like activity of silicon nanowire arrays.
Topics: Animals; Biochemistry; Cell Line; Cell Survival; Coloring Agents; Fibroblasts; Mice; Nanowires; Oxidoreductases; Silicon; Tetrazolium Salts; Thiazoles | 2013 |
Synthesis and biological evaluation of some pyrazoline derivatives bearing a dithiocarbamate moiety as new cholinesterase inhibitors.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cell Culture Techniques; Cell Survival; Cholinesterase Inhibitors; Drug Design; Inhibitory Concentration 50; Mice; Molecular Structure; NIH 3T3 Cells; Pyrazoles; Tetrazolium Salts; Thiazoles; Thiocarbamates | 2013 |
Evaluation of methods for testing the susceptibility of clinical Mycobacterium tuberculosis isolates to pyrazinamide.
Topics: Amidohydrolases; Antitubercular Agents; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Pyrazinamide; Tetrazolium Salts; Thiazoles; Xanthenes | 2013 |
Fourier transform infrared spectroscopy imaging of live epithelial cancer cells under non-aqueous media.
Topics: Caco-2 Cells; Calcium Fluoride; Cell Adhesion; Cell Survival; Epirubicin; Epithelial Cells; Equipment Design; Humans; Mineral Oil; Neoplasms, Glandular and Epithelial; Oils; Paraffin; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: hirsutanol A inhibits tumor growth through ROS production.
Topics: Agaricales; Animals; Apoptosis; Cell Death; Cell Line, Tumor; Cytochromes c; Cytosol; Flow Cytometry; Humans; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasm Transplantation; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Enhanced cytotoxicity for colon 26 cells using doxorubicin-loaded sorbitan monooleate (Span 80) vesicles.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Drug Delivery Systems; Female; Flow Cytometry; Hexoses; Liposomes; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Tetrazolium Salts; Thiazoles; Transport Vesicles | 2013 |
Biruloquinone, an acetylcholinesterase inhibitor produced by lichen-forming fungus Cladonia macilenta.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Ascomycota; Cell Line; Cell Survival; Cholinesterase Inhibitors; Hydrogen Peroxide; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neuroprotective Agents; Quinones; Rats; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Cucurbitane-type triterpenoids from the fruit pulp of Momordica charantia.
Topics: Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Diterpenes; Fruit; Humans; Magnetic Resonance Spectroscopy; Momordica; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Triterpenes | 2012 |
Ochnaflavone and ochnaflavone 7-O-methyl ether two antibacterial biflavonoids from Ochna pretoriensis (Ochnaceae).
Topics: Animals; Anti-Bacterial Agents; Bacteria; Chlorocebus aethiops; Coloring Agents; Drug Screening Assays, Antitumor; Flavonoids; Humans; Microbial Sensitivity Tests; Mutagens; Ochnaceae; Plant Extracts; Plant Leaves; Rats; Salmonella typhimurium; Tetrazolium Salts; Thiazoles; Vero Cells | 2012 |
HPLC-MTT assay: anticancer activity of aqueous garlic extract is from allicin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colonic Neoplasms; Coloring Agents; Disulfides; Garlic; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Plant Extracts; Sulfinic Acids; Tetrazolium Salts; Thiazoles | 2013 |
Rapid screening of potential autophagic inductor agents using mammalian cell lines.
Topics: Animals; Autophagy; Cell Line; Cell Survival; Drug Discovery; Gentian Violet; Humans; Hydrogen Peroxide; Indicators and Reagents; Mice; Microscopy, Fluorescence; Neutral Red; Reproducibility of Results; Statistics, Nonparametric; Staurosporine; Tetrazolium Salts; Thiazoles | 2013 |
[Triiodothyronine does not increase osteogenic differentiation reduced by age in bone marrow mesenchymal stem cells of female rats].
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Bone Marrow Cells; Calcification, Physiologic; Cell Differentiation; Cells, Cultured; Collagen; Female; Mesenchymal Stem Cells; Models, Animal; Osteogenesis; Phenotype; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Triiodothyronine | 2013 |
Lectin from Canavalia brasiliensis (ConBr) protects hippocampal slices against glutamate neurotoxicity in a manner dependent of PI3K/Akt pathway.
Topics: Animals; Blotting, Western; Canavalia; Carbohydrate Metabolism; Cell Survival; Chromones; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Mice; Mitogen-Activated Protein Kinases; Morpholines; Neuroprotective Agents; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Lectins; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Inhibition of connective tissue growth factor suppresses hepatic stellate cell activation in vitro and prevents liver fibrosis in vivo.
Topics: Animals; Blotting, Western; Cell Line; Cell Proliferation; Connective Tissue Growth Factor; Disease Models, Animal; Flow Cytometry; Gene Silencing; Hepatic Stellate Cells; Histocytochemistry; Humans; Lentivirus; Liver Cirrhosis; Male; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2014 |
AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration.
Topics: Angiotensin II; Blotting, Western; Calcium; Cations, Divalent; Cell Line; Cell Proliferation; Cytoplasm; Gene Expression Profiling; Humans; Losartan; Mesangial Cells; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Staining and Labeling; Tetrazolium Salts; Thiazoles; TRPC Cation Channels; TRPC6 Cation Channel; Trypan Blue | 2014 |
Protective effects of resveratrol on glutamate-induced damages in murine brain cultures.
Topics: Animals; Antioxidants; Biphenyl Compounds; Brain; Cells, Cultured; Coloring Agents; Copper; Ethidium; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; Iron; Mesencephalon; Mice; Mice, Inbred C57BL; Neurites; Neurons; Organ Culture Techniques; Picrates; Pregnancy; Propidium; Resveratrol; Spectrophotometry, Atomic; Stilbenes; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2013 |
Unraveling the mechanisms behind the enhanced MTT conversion by irradiated breast cancer cells.
Topics: Breast Neoplasms; Cadherins; Cell Communication; Cell Count; Cell Line, Tumor; Female; Humans; Nitroblue Tetrazolium; Permeability; Tetrazolium Salts; Thiazoles | 2013 |
Anticancer effect of arsenic trioxide on cholangiocarcinoma: in vitro experiments and in vivo xenograft mouse model.
Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholangiocarcinoma; Disease Models, Animal; Heterografts; Humans; Mice, Inbred BALB C; Mice, Nude; Oxides; Staining and Labeling; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2014 |
Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Cell Line, Tumor; Checkpoint Kinase 2; Coloring Agents; Drug Resistance, Multiple; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Flavonoids; Fluorescent Dyes; G2 Phase; Genes, p53; Humans; NF-kappa B; Propidium; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2013 |
Identification of CD44+ cancer stem cells in human gastric cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Flow Cytometry; Fluorouracil; Humans; Hyaluronan Receptors; Mice; Mice, SCID; Neoplastic Stem Cells; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2013 |
A segment of 97 amino acids within the translocation domain of Clostridium difficile toxin B is essential for toxicity.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Bacterial Toxins; Biological Assay; Cell Fractionation; Cysteine Proteases; DNA Primers; Fluorescence; Glucosyltransferases; Immunoprecipitation; Kaplan-Meier Estimate; Mice; Polymerase Chain Reaction; Protein Structure, Tertiary; Tetrazolium Salts; Thiazoles; Vero Cells | 2013 |
Role of HMGB1 in proliferation and migration of human gingival and periodontal ligament fibroblasts.
Topics: Cell Count; Cell Culture Techniques; Cell Movement; Cell Proliferation; Chemotactic Factors; Chemotaxis; Coloring Agents; Fibroblasts; Gentian Violet; Gingiva; HMGB1 Protein; Humans; Periodontal Ligament; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
The role of autophagy in Parkinson's disease: rotenone-based modeling.
Topics: Apoptosis; Autophagy; Blotting, Western; Cell Death; Cell Line; Cell Proliferation; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Parkinson Disease, Secondary; Reactive Oxygen Species; Rotenone; Tetrazolium Salts; Thiazoles; Uncoupling Agents | 2013 |
HYS-32, a novel analogue of combretastatin A-4, enhances connexin43 expression and gap junction intercellular communication in rat astrocytes.
Topics: 4-Butyrolactone; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Astrocytes; Blotting, Western; Cell Communication; Cells, Cultured; Coloring Agents; Connexin 43; Enzyme Inhibitors; Female; Gap Junctions; Image Processing, Computer-Assisted; Male; Microscopy, Fluorescence; Naphthalenes; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Signal Transduction; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
Insulinotropic and β-cell protective action of cuminaldehyde, cuminol and an inhibitor isolated from Cuminum cyminum in streptozotocin-induced diabetic rats.
Topics: Alkanes; Animals; Benzaldehydes; Benzyl Alcohols; Blood Glucose; Calcium; Cells, Cultured; Cuminum; Cymenes; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Glucose Tolerance Test; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Plant Extracts; Rats; Spectroscopy, Fourier Transform Infrared; Streptozocin; Tetrazolium Salts; Thiazoles | 2013 |
Antiangiogenic activity and direct antitumor effect from a sulfated polysaccharide isolated from seaweed.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aorta; Apoptosis; Cell Cycle; Cell Line; Chick Embryo; Chorioallantoic Membrane; Collagen; Drug Combinations; Endothelial Cells; Flow Cytometry; HeLa Cells; Humans; Laminin; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Plant Extracts; Polysaccharides; Proteoglycans; Rabbits; Seaweed; Tetrazolium Salts; Thiazoles | 2013 |
The protective effect of silybin against lasalocid cytotoxic exposure on chicken and rat cell lines.
Topics: Animals; Antioxidants; Cell Line; Chickens; Cytoprotection; Dose-Response Relationship, Drug; Ionophores; L-Lactate Dehydrogenase; Lasalocid; Myoblasts; Rats; Rosaniline Dyes; Silybin; Silymarin; Tetrazolium Salts; Thiazoles | 2013 |
Cytotoxic effect of ethanol extract of microalga, Chaetoceros calcitrans, and its mechanisms in inducing apoptosis in human breast cancer cell line.
Topics: Annexin A5; Apoptosis; Biological Products; Breast Neoplasms; Cell Cycle; Cell Proliferation; Ethanol; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; MCF-7 Cells; Microalgae; Propidium; Regression Analysis; Tamoxifen; Tetrazolium Salts; Thiazoles | 2013 |
Use of MTT assay for determination of the biofilm formation capacity of microorganisms in metalworking fluids.
Topics: Biofilms; Biomedical Research; Disinfectants; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Metallurgy; Microbial Viability; Occupational Diseases; Occupational Exposure; Tetrazolium Salts; Thiazoles | 2013 |
Diazepam inhibits proliferation of human glioblastoma cells through triggering a G0/G1 cell cycle arrest.
Topics: Antimetabolites; Benzimidazoles; Blotting, Western; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Diazepam; Fluorescent Dyes; G1 Phase; G1 Phase Cell Cycle Checkpoints; GABA Modulators; Glioblastoma; Humans; L-Lactate Dehydrogenase; Resting Phase, Cell Cycle; S Phase; Tetrazolium Salts; Thiazoles | 2013 |
Six1 promotes proliferation of pancreatic cancer cells via upregulation of cyclin D1 expression.
Topics: Analysis of Variance; Animals; Blotting, Western; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin D1; DNA Primers; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Mice; Mice, Inbred BALB C; Microarray Analysis; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2013 |
Effect of nifedipine on the expression of keratinocyte growth factor and its receptor in cocultured/monocultured fibroblasts and keratinocytes.
Topics: Calcium Channel Blockers; Cell Communication; Cell Culture Techniques; Cell Membrane; Cell Proliferation; Coculture Techniques; Coloring Agents; Fibroblast Growth Factor 7; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Keratinocytes; Nifedipine; Receptor, Fibroblast Growth Factor, Type 2; Tetrazolium Salts; Thiazoles | 2013 |
Use of the tetrazolium salt MTT to measure cell viability effects of the bacterial antagonist Lysobacter enzymogenes on the filamentous fungus Cryphonectria parasitica.
Topics: Antibiosis; Antifungal Agents; Cell Count; Lysobacter; Microbial Viability; Saccharomycetales; Tetrazolium Salts; Thiazoles | 2013 |
Influence of the surface coating on the cytotoxicity, genotoxicity and uptake of gold nanoparticles in human HepG2 cells.
Topics: Cell Survival; Citric Acid; Coated Materials, Biocompatible; Comet Assay; DNA Damage; Fatty Acids; Genomic Instability; Gold; Hep G2 Cells; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Particle Size; Sulfhydryl Compounds; Surface Properties; Tetrazolium Salts; Thiazoles | 2013 |
The noncellular reduction of MTT tetrazolium salt by TiO₂ nanoparticles and its implications for cytotoxicity assays.
Topics: Animals; Biological Assay; Catalysis; Cell Line; Cell Line, Tumor; Cell Survival; Coloring Agents; Cricetulus; HeLa Cells; Humans; Metal Nanoparticles; Mice; Oxidation-Reduction; Tetrazolium Salts; Thiazoles; Titanium; Toxicity Tests; Ultraviolet Rays | 2013 |
Stimulatory effects of glucose and Porphyromonas gingivalis lipopolysaccharide on the secretion of inflammatory mediators from human macrophages.
Topics: Calcium; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chelating Agents; Coloring Agents; Dinoprostone; Egtazic Acid; Glucose; Humans; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Mitochondria; Oxidoreductases; Porphyromonas gingivalis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-dependent pathway.
Topics: Acidosis; Amiloride; Animals; Blotting, Western; Cell Cycle; Cell Proliferation; Disease Progression; Flow Cytometry; Fluoresceins; Hydrogen-Ion Concentration; Mesangial Cells; Rats; Renal Insufficiency, Chronic; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Influence of serum and albumin on the in vitro anandamide cytotoxicity toward C6 glioma cells assessed by the MTT cell viability assay: implications for the methodology of the MTT tests.
Topics: Albumins; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media; Drug Screening Assays, Antitumor; Endocannabinoids; Glioma; Polyunsaturated Alkamides; Rats; Serum; Tetrazolium Salts; Thiazoles | 2013 |
Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Flow Cytometry; Gene Expression Regulation; Homeostasis; L-Lactate Dehydrogenase; Neurodegenerative Diseases; Neurons; PC12 Cells; Peptide Fragments; Rats; Resveratrol; rho-Associated Kinases; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
In vitro assessment of the cytotoxic, apoptotic, and mutagenic potentials of isatin.
Topics: Animals; Apoptosis; Cell Division; Cell Nucleus; Cell Survival; CHO Cells; Cricetinae; Cricetulus; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Isatin; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles | 2013 |
Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines.
Topics: Animals; Benzalkonium Compounds; Cattle; Cell Line; Cell Survival; Coloring Agents; Conjunctiva; Epithelial Cells; Epithelium, Corneal; Humans; Neutral Red; Preservatives, Pharmaceutical; Rabbits; Tetrazolium Salts; Thiazoles | 2013 |
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
Topics: Analysis of Variance; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Genetic Vectors; HEK293 Cells; Humans; Immunoblotting; Immunoprecipitation; Lentivirus; Male; Mutation, Missense; Nuclear Proteins; Nuclear Receptor Coactivator 3; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Novel ferrocenyl-containing N-acetyl-2-pyrazolines inhibit in vitro angiogenesis and human lung cancer growth by interfering with F-actin stress fiber polimeryzation.
Topics: Actins; Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Collagen; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Combinations; Ferrous Compounds; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Laminin; Lung Neoplasms; Neovascularization, Pathologic; Polymerization; Proteoglycans; Pyrazoles; Tetrazolium Salts; Thiazoles; Thiophenes | 2013 |
Simvastatin induces apoptosis and disruption of the actin cytoskeleton in human dental pulp cells and periodontal ligament fibroblasts.
Topics: Actin Cytoskeleton; Adolescent; Adult; Apoptosis; Cell Culture Techniques; Cell Nucleus; Cell Shape; Cell Survival; Cells, Cultured; Coloring Agents; Dental Pulp; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Periodontal Ligament; Phalloidine; Simvastatin; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2013 |
Imidazoacridinone derivatives as efficient sensitizers in photoantimicrobial chemotherapy.
Topics: Analysis of Variance; Candida albicans; Cell Death; Cell Line; Heterocyclic Compounds, 4 or More Rings; Humans; Keratinocytes; Light; Microscopy, Fluorescence; Molecular Structure; Photosensitizing Agents; Tetrazolium Salts; Thiazoles | 2013 |
Synthesis of new quinolinequinone derivatives and preliminary exploration of their cytotoxic properties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coloring Agents; Cytochromes c; Drug Screening Assays, Antitumor; Electrochemistry; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microwaves; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Oxygen Consumption; Quinolines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2013 |
Rattle-structured multifunctional nanotheranostics for synergetic chemo-/radiotherapy and simultaneous magnetic/luminescent dual-mode imaging.
Topics: Antineoplastic Agents; Cell Survival; Chemoradiotherapy; Cisplatin; Coloring Agents; Contrast Media; Drug Delivery Systems; Gadolinium; HeLa Cells; Humans; Light; Luminescence; Magnetic Resonance Imaging; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Neoplasms; Particle Size; Porosity; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2013 |
Development of a new cell culture-based method and optimized protocol for the detection of enteric viruses.
Topics: Animals; Cell Line; Clinical Laboratory Techniques; Colorimetry; DNA Viruses; Gastrointestinal Tract; Humans; RNA Viruses; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Virus Cultivation; Virus Diseases | 2013 |
A new isobenzofuranone from the mangrove endophytic fungus Penicillium sp. (ZH58).
Topics: Benzofurans; Cell Line; China; Complex Mixtures; Fermentation; Humans; Inhibitory Concentration 50; Molecular Structure; Penicillium; Rhizophoraceae; Tetrazolium Salts; Thiazoles | 2013 |
Annexin A1 protein regulates the expression of PMVEC cytoskeletal proteins in CBDL rat serum-induced pulmonary microvascular remodeling.
Topics: Animals; Annexin A1; Cell Nucleus; Cell Proliferation; Common Bile Duct; Cytokines; Cytoplasm; Cytoskeleton; Gene Expression Regulation; Hepatopulmonary Syndrome; Humans; Lung; Microcirculation; Phenotype; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Toxicity of allyl esters in insect cell lines and in Spodoptera littoralis larvae.
Topics: Animals; Cell Line; Coleoptera; Drosophila melanogaster; Esters; Insecticides; Larva; Moths; Species Specificity; Spodoptera; Tetrazolium Salts; Thiazoles; Trypan Blue | 2012 |
Inhibition of autophagy enhances cisplatin cytotoxicity in human adenoid cystic carcinoma cells of salivary glands.
Topics: Adenine; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carcinoma, Adenoid Cystic; Cell Culture Techniques; Cell Death; Cell Line, Tumor; Cell Survival; Chloroquine; Cisplatin; Coloring Agents; Drug Resistance, Neoplasm; Green Fluorescent Proteins; Humans; Luminescent Agents; Membrane Proteins; Microtubule-Associated Proteins; Salivary Gland Neoplasms; Tetrazolium Salts; Thiazoles | 2013 |
Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding.
Topics: Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Discovery; Humans; Immunoblotting; Neoplasms; Piperazines; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Tetrazolium Salts; Thiazoles | 2013 |
Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells.
Topics: Annexin A5; Apoptosis; Artemether; Artemisinins; Blotting, Western; Cell Line, Tumor; Cell Movement; Drugs, Chinese Herbal; Fluorescein-5-isothiocyanate; Glioma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Vascular Cell Adhesion Molecule-1 | 2013 |
Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasis.
Topics: Animals; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; Drug Design; Drug Discovery; ErbB Receptors; Humans; Indicators and Reagents; Lapatinib; Morpholines; Neglected Diseases; Phosphotransferases; Quinazolines; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2013 |
Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Coloring Agents; Computer Simulation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; High-Throughput Screening Assays; Humans; Indicators and Reagents; Male; Models, Molecular; Phosphorylation; Structure-Activity Relationship; Testicular Neoplasms; Tetrazolium Salts; Thiazoles | 2013 |
The FUS1 gene inhibits EC109 cell growth mediated by a lentivirus vector.
Topics: Carcinoma; Cell Line, Tumor; Cell Proliferation; Esophageal Neoplasms; Gene Expression; Genes, Tumor Suppressor; Genetic Vectors; Humans; Lentivirus; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Proteins | 2013 |
Two new vinblastine-type N-oxide alkaloids from Catharanthus roseus.
Topics: Catharanthus; Cell Proliferation; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; MCF-7 Cells; Molecular Structure; Plant Leaves; Tetrazolium Salts; Thiazoles; Vinblastine | 2013 |
Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Coloring Agents; Cross-Linking Reagents; Darkness; Dermatitis, Phototoxic; Fluorescent Dyes; Light; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Porphyrins; Prodrugs; Stilbenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tubulin | 2013 |
Splice variants DNMT3B4 and DNMT3B7 overexpression inhibit cell proliferation in 293A cell line.
Topics: Blotting, Western; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA Primers; Flow Cytometry; Gene Expression Regulation; Gene Silencing; Gentamicins; HEK293 Cells; Humans; Plasmids; Protein Isoforms; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.
Topics: Adenoviridae; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Chlorocebus aethiops; DNA Primers; Elafin; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Fluorescent Antibody Technique; Gene Knockdown Techniques; Genetic Vectors; Herpes Genitalis; Herpesvirus 2, Human; Humans; Interferon Regulatory Factor-3; Interleukin-8; Mice; Mice, Transgenic; NF-kappa B; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Vero Cells; Viral Load; Virus Attachment; Virus Replication | 2013 |
Synthesis and cytotoxicity of brefeldin A conjugated monomethoxy-poly(ethylene glycol)-b-poly(L-lactide) polymeric micelles.
Topics: Antineoplastic Agents; Brefeldin A; Drug Carriers; Hep G2 Cells; Humans; Micelles; Molecular Weight; Particle Size; Polyesters; Polyethylene Glycols; Tetrazolium Salts; Thiazoles | 2013 |
Nonlinear optical response and biological applications of a series of pyrimidine-based molecules for copper(II) ion probe.
Topics: Biosensing Techniques; Computer Simulation; Copper; Electrons; Hep G2 Cells; Humans; Ions; Magnetic Resonance Spectroscopy; Metals; Nonlinear Dynamics; Optics and Photonics; Pyrimidines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2013 |
[Comparison of four cytotoxicity assays for determining the acute toxicity of diesel exhaust particulate extracts].
Topics: Air Pollutants; Bronchi; Cell Line; Epithelial Cells; Humans; L-Lactate Dehydrogenase; Neutral Red; Particle Size; Tetrazolium Salts; Thiazoles; Toxicity Tests, Acute; Vehicle Emissions | 2013 |
Uniform magnesium silicate hollow spheres as high drug-loading nanocarriers for cancer therapy with low systemic toxicity.
Topics: Animals; Antineoplastic Agents; Drug Carriers; Endocytosis; Female; Fluorescein-5-isothiocyanate; Hemolysis; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Lysosomes; Magnesium Silicates; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Nanoparticles; Neoplasm Transplantation; Neoplasms; Particle Size; Tetrazolium Salts; Thiazoles | 2013 |
Cancer targeting gene-viro-therapy for pancreatic cancer using oncolytic adenovirus ZD55-IL-24 in immune-competent mice.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cytokines; Flow Cytometry; Genes, Reporter; Genetic Therapy; Gentian Violet; In Situ Nick-End Labeling; Interferon-gamma; Interleukins; Mice; Oncolytic Virotherapy; Pancreatic Neoplasms; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2013 |
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Female; Humans; Microscopy, Confocal; Phosphorylation; Proto-Oncogene Proteins c-fos; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Trans-Activators; Viral Regulatory and Accessory Proteins | 2013 |
Effects of allogenous periosteal-derived cells transfected with adenovirus-mediated BMP-2 on repairing defects of the mandible in rabbits.
Topics: Adenoviridae; Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Bone Substitutes; Cell Culture Techniques; Cell Proliferation; Cell Transplantation; Ceramics; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Guided Tissue Regeneration; Humans; In Situ Hybridization; Mandibular Diseases; Osteogenesis; Periosteum; Rabbits; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Transfection; Transforming Growth Factor beta; Transplantation, Homologous | 2013 |
Activation of the B cell antigen receptor triggers reactivation of latent Kaposi's sarcoma-associated herpesvirus in B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line, Tumor; Chlorocebus aethiops; Chromatin Immunoprecipitation; DNA Primers; DNA-Binding Proteins; Fluorescent Antibody Technique; HEK293 Cells; Herpesvirus 8, Human; Humans; Immunoblotting; Phosphatidylinositol 3-Kinase; Polymerase Chain Reaction; Receptors, Antigen, B-Cell; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription Factors; Vero Cells; Virus Activation; Virus Latency; X-Box Binding Protein 1 | 2013 |
Cytotoxicity of TiO₂ nanoparticles and their detoxification in a freshwater system.
Topics: Adsorption; Biodegradation, Environmental; Cell Count; Cell Membrane Permeability; Cell Survival; Environmental Pollutants; Fresh Water; Metal Nanoparticles; Microscopy, Electron, Scanning; Particle Size; Reactive Oxygen Species; Scenedesmus; Tetrazolium Salts; Thiazoles; Titanium; Toxicity Tests; Ultraviolet Rays | 2013 |
Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Berberine; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Flow Cytometry; Humans; L-Lactate Dehydrogenase; Medicine, Chinese Traditional; Microscopy, Fluorescence; Prohibitins; Repressor Proteins; RNA, Messenger; S Phase; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Vimentin | 2012 |
High levels of circulating HMGB1 as a biomarker of acute liver failure in patients with viral hepatitis E.
Topics: Adult; Biomarkers; Colorimetry; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Hepatitis E; HMGB1 Protein; Humans; Leukocytes, Mononuclear; Liver Failure, Acute; Male; Real-Time Polymerase Chain Reaction; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles | 2013 |
Cobalt triggers necrotic cell death and atrophy in skeletal C2C12 myotubes.
Topics: Atrophy; Autophagy; Blotting, Western; Cell Death; Cell Line; Cobalt; Coloring Agents; Fluorometry; Immunohistochemistry; Indicators and Reagents; Muscle Fibers, Skeletal; Myoblasts; Necrosis; NF-kappa B; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Prostheses and Implants; Proteasome Endopeptidase Complex; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Multilayer scaffold of electrospun PLA-PCL-collagen nanofibers as a dural substitute.
Topics: Absorption; Acridine Orange; Animals; Cell Adhesion; Cell Proliferation; Cell Survival; Collagen; Dura Mater; Female; Humans; Male; Materials Testing; Microscopy, Electron, Scanning; Nanofibers; Polyesters; Rabbits; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Water | 2013 |
Structural insights into Aβ42 oligomers using site-directed spin labeling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Circular Dichroism; Electron Spin Resonance Spectroscopy; HeLa Cells; Humans; Microscopy, Electron, Transmission; PC12 Cells; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Rats; Spin Labels; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2013 |
Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells.
Topics: Analysis of Variance; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; DNA Primers; Luciferases; Mice; Myosin Heavy Chains; Pluripotent Stem Cells; Repressor Proteins; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2013 |
Activation of the kinin B1 receptor attenuates melanoma tumor growth and metastasis.
Topics: Analysis of Variance; Blotting, Western; Cell Line, Tumor; Fluorescent Dyes; Gene Expression Profiling; Humans; Immunohistochemistry; Kisspeptins; Melanoma; Neoplasm Metastasis; Receptor, Bradykinin B1; Tetrazolium Salts; Thiazoles | 2013 |
Critical role of TRPC6 channels in the development of human renal cell carcinoma.
Topics: Blotting, Western; Carcinoma, Renal Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Primers; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles; TRPC Cation Channels; TRPC6 Cation Channel | 2013 |
N-Epsilon-(carboxymethyl)lysine is unable to induce endothelial dysfunction but is able to attenuate Ages-induced endothelium damage in human umbilical vein endothelial cells.
Topics: Acridine Orange; Adult; Algorithms; Apoptosis; Data Interpretation, Statistical; Endothelial Cells; Endothelium, Vascular; Ethidium; Female; Fluorescence Polarization; Glycation End Products, Advanced; Humans; Intercellular Adhesion Molecule-1; Lysine; Pregnancy; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1; Umbilical Veins | 2013 |
MicroRNA-98 sensitizes cisplatin-resistant human lung adenocarcinoma cells by up-regulation of HMGA2.
Topics: Antineoplastic Agents; bcl-X Protein; Blotting, Western; Cell Line, Tumor; Cisplatin; Coloring Agents; Drug Resistance, Neoplasm; Flow Cytometry; Genetic Vectors; HMGA2 Protein; Humans; In Situ Hybridization; Luciferases; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection | 2013 |
Homocysteine-induced hypermethylation of DDAH2 promoter contributes to apoptosis of endothelial cells.
Topics: Amidohydrolases; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Survival; Coloring Agents; Endothelial Cells; Homocysteine; Methylation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Repressor Proteins; Tetrazolium Salts; Thiazoles | 2013 |
Electrospun biodegradable calcium containing poly(ester-urethane)urea: synthesis, fabrication, in vitro degradation, and biocompatibility evaluation.
Topics: Absorbable Implants; Absorption; Amines; Animals; Biocompatible Materials; Calcium; Cell Survival; Elastomers; Hydrogen-Ion Concentration; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Scanning; Molecular Weight; Polyurethanes; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Water | 2013 |
Expression and role of miR-34a in bladder cancer.
Topics: Adult; Aged; Apoptosis; Biomarkers, Tumor; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Prognosis; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Urinary Bladder Neoplasms | 2013 |
Amyloid-β peptide-induced extracellular S100A9 depletion is associated with decrease of antimicrobial peptide activity in human THP-1 monocytes.
Topics: Amyloid beta-Peptides; Antimicrobial Cationic Peptides; Blotting, Western; Calcium; Calgranulin B; Cells, Cultured; Colony-Forming Units Assay; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Immunity, Innate; Microscopy, Fluorescence; Monocytes; Recombinant Proteins; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2013 |
The induction expression of human β-defensins in gingival epithelial cells and fibroblasts.
Topics: beta-Defensins; Biopsy; Cells, Cultured; Fibroblasts; Gingiva; Humans; Interleukin-1beta; Keratinocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.
Topics: Animals; Biomarkers; Brain Chemistry; Cell Survival; Cerebrovascular Disorders; Coloring Agents; Cytokines; Genes, MHC Class II; Glutamic Acid; Hydrogen Peroxide; Inflammation; Male; Microarray Analysis; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phycobilins; Phycocyanin; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Spirulina; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2013 |
Inhibition of hepatitis B virus production in vitro by proteasome inhibitor MG132.
Topics: Blotting, Western; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hepatitis B virus; Humans; In Vitro Techniques; Leupeptins; Polymerase Chain Reaction; Proteasome Inhibitors; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2013 |
New insights into mycotoxin mixtures: the toxicity of low doses of Type B trichothecenes on intestinal epithelial cells is synergistic.
Topics: Algorithms; Caco-2 Cells; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Humans; Intestinal Mucosa; Mycotoxins; Tetrazolium Salts; Thiazoles; Trichothecenes | 2013 |
Silencing of ghrelin receptor expression inhibits endometrial cancer cell growth in vitro and in vivo.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Disease Progression; Endometrial Neoplasms; Female; Flow Cytometry; Gene Silencing; Genetic Vectors; Ghrelin; Humans; Immunohistochemistry; Lentivirus; Mice; Mice, Inbred NOD; Microarray Analysis; Real-Time Polymerase Chain Reaction; Receptors, Ghrelin; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2013 |
(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.
Topics: Annexins; Antimetabolites; Apoptosis; Benzophenones; Bromodeoxyuridine; Caspases; Cell Death; Cell Division; Cell Membrane; Cell Survival; Coloring Agents; Comet Assay; DNA Fragmentation; G2 Phase; HL-60 Cells; Humans; Membrane Potential, Mitochondrial; Models, Molecular; Polymerization; Tetrazolium Salts; Thiazoles; Tubulin; Tubulin Modulators | 2013 |
Adhesion and biofilm formation by oral streptococci on different commercial brackets.
Topics: Aluminum Oxide; Bacterial Adhesion; Bacteriological Techniques; Biofilms; Ceramics; Coloring Agents; Composite Resins; Culture Media; Dental Materials; Dental Plaque; Gold Alloys; Humans; Materials Testing; Mouth; Orthodontic Brackets; Polycarboxylate Cement; Saliva; Stainless Steel; Streptococcus; Streptococcus gordonii; Streptococcus mutans; Streptococcus oralis; Streptococcus sanguis; Streptococcus sobrinus; Tetrazolium Salts; Thiazoles; Titanium | 2013 |
In vitro cellular detoxification of triethylene glycol dimethacrylate by adduct formation with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Cell Culture Techniques; Cell Survival; Chromatography, High Pressure Liquid; Coloring Agents; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Electrophoresis, Capillary; Extracellular Space; Fibroblasts; Methacrylates; Mice; Polyethylene Glycols; Polymethacrylic Acids; Protective Agents; Swiss 3T3 Cells; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2013 |
NVP-BEZ235, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, prominently enhances radiosensitivity of prostate cancer cell line PC-3.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Flow Cytometry; Humans; Imidazoles; Male; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms; Quinolines; Radiation Tolerance; Radiation, Ionizing; Radiopharmaceuticals; Receptors, Androgen; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2013 |
New immunological investigations on Helicobacter pylori-induced gastric ulcer in patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Female; Helicobacter Infections; Helicobacter pylori; Humans; Interleukin-1beta; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Staining and Labeling; Stomach Ulcer; Tetrazolium Salts; Thiazoles; Young Adult | 2013 |
Concentration-dependent induction of reactive oxygen species, cell cycle arrest and apoptosis in human liver cells after nickel nanoparticles exposure.
Topics: Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line; Cell Survival; Coloring Agents; DNA Fragmentation; Glutathione; Humans; Membrane Potential, Mitochondrial; Metal Nanoparticles; Neutral Red; Nickel; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2015 |
In vitro cytotoxicity of white MTA, MTA Fillapex® and Portland cement on human periodontal ligament fibroblasts.
Topics: Aluminum Compounds; Calcium Compounds; Cell Count; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dental Cements; Drug Combinations; Ferric Compounds; Fibroblasts; Humans; Materials Testing; Nitric Oxide; Nitrites; Oxides; Periodontal Ligament; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2013 |
Evaluation of a β-calcium metaphosphate bone Graft containing bone morphogenetic protein-7 in rabbit maxillary defects.
Topics: Absorbable Implants; Alkaline Phosphatase; Animals; Bone Density; Bone Morphogenetic Protein 7; Calcium Phosphates; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Diffusion; Female; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Maxillary Diseases; Mesenchymal Stem Cells; Osteocalcin; Osteogenesis; Rabbits; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Scaffolds; X-Ray Microtomography | 2014 |
Low-power laser irradiation promotes the proliferation and osteogenic differentiation of human periodontal ligament cells via cyclic adenosine monophosphate.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Alkaline Phosphatase; Anthraquinones; Bone Morphogenetic Protein 2; Calcium; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Proliferation; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Cyclic AMP; Gene Expression; Humans; L-Lactate Dehydrogenase; Lasers, Semiconductor; Low-Level Light Therapy; Osteocalcin; Osteogenesis; Periodontal Ligament; Radiation Dosage; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Development of a new model system to study microbial colonization on dentures.
Topics: Acrylic Resins; Antifungal Agents; Biofilms; Borates; Candida albicans; Colorimetry; Coloring Agents; Dental Materials; Denture Bases; Denture Cleansers; Dentures; Gentian Violet; Humans; Microbial Viability; Microscopy, Confocal; Microscopy, Electron, Scanning; Polystyrenes; Porosity; Sulfates; Surface Properties; Tetrazolium Salts; Thiazoles; Tooth, Artificial | 2013 |
HIF1 regulates WSB-1 expression to promote hypoxia-induced chemoresistance in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Hypoxia; DNA Damage; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteins; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2013 |
Assessment of the hemolytic activity and cytotoxicity of different PEG-based solubilizing agents.
Topics: Caco-2 Cells; Cell Survival; Coloring Agents; Erythrocytes; Excipients; Hemolysis; Humans; In Vitro Techniques; Polyethylene Glycols; Solvents; Tetrazolium Salts; Thiazoles | 2013 |
Radiation up-regulates the expression of VEGF in a canine oral melanoma cell line.
Topics: Animals; Apoptosis; Cell Line, Tumor; Dogs; Dose-Response Relationship, Radiation; Enzyme-Linked Immunosorbent Assay; Melanoma; Mouth Neoplasms; Radiation Tolerance; Tetrazolium Salts; Thiazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
In vitro and in vivo characterization of porcine acellular dermal matrix for gingival augmentation procedures.
Topics: Acellular Dermis; Adenylate Kinase; Animals; Cell Culture Techniques; Cell Line; Cell Survival; Cell Transplantation; Colorimetry; Coloring Agents; Female; Fibroblasts; Gingiva; Gingivoplasty; Guided Tissue Regeneration, Periodontal; Human Umbilical Vein Endothelial Cells; Humans; Indicators and Reagents; Keratinocytes; Mice; Mice, Nude; Osteoblasts; Subcutaneous Tissue; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering; Tissue Scaffolds | 2014 |
Green synthetic, multifunctional hybrid micelles with shell embedded magnetic nanoparticles for theranostic applications.
Topics: Antineoplastic Agents; Doxycycline; Drug Carriers; Drug Design; Ferric Compounds; Green Chemistry Technology; HeLa Cells; Humans; Magnetic Resonance Imaging; Magnetics; Mass Spectrometry; Micelles; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Peptides; Poloxamer; Polymers; Solvents; Tetrazolium Salts; Thiazoles | 2013 |
An insight into the hepatocellular death induced by amphetamines, individually and in combination: the involvement of necrosis and apoptosis.
Topics: Adenosine Triphosphate; Amphetamines; Apoptosis; Blotting, Western; Caspase 3; Caspase 7; Cell Death; Cell Line; Cell Survival; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Energy Metabolism; Flow Cytometry; Humans; Membranes; Mitochondria; Necrosis; Neutral Red; Real-Time Polymerase Chain Reaction; Reverse Transcription; RNA; Tetrazolium Salts; Thiazoles | 2013 |
Multi-shell structured fluorescent-magnetic nanoprobe for target cell imaging and on-chip sorting.
Topics: Cell Line, Tumor; Cell Separation; Cell Survival; Fluorescent Dyes; HeLa Cells; HL-60 Cells; Humans; Indoles; K562 Cells; Magnetics; Microfluidics; Nanostructures; Neoplasms; Polyethylene Glycols; Polymers; Quantum Dots; Tetrazolium Salts; Thiazoles | 2013 |
In vitro cytotoxicity assessment of two heavy metal salts in a fish cell line (RF).
Topics: Animals; Cadmium; Carps; Cell Line; Dose-Response Relationship, Drug; Environmental Monitoring; Maximum Tolerated Dose; Neutral Red; Rosaniline Dyes; Tetrazolium Salts; Thiazoles; Toxicity Tests; Zinc | 2014 |
Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Transformation, Neoplastic; DNA Primers; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Flow Cytometry; Fluorouracil; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Tumor Cells, Cultured | 2014 |
Aptamer-directed synthesis of multifunctional lanthanide-doped porous nanoprobes for targeted imaging and drug delivery.
Topics: Cell Line; Cell Line, Tumor; Contrast Media; DNA; Drug Delivery Systems; Humans; Lanthanoid Series Elements; MCF-7 Cells; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Neoplasms; Oligonucleotides; Porosity; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2013 |
Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Synergism; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2014 |
Arsanilic acid causes apoptosis and oxidative stress in rat kidney epithelial cells (NRK-52e cells) by the activation of the caspase-9 and -3 signaling pathway.
Topics: Animals; Apoptosis; Arsanilic Acid; Blotting, Western; Caspase 3; Caspase 9; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Kidney; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2014 |
Antidermatophytic and antileishmanial activities of essential oils from Lippia gracilis Schauer genotypes.
Topics: Antifungal Agents; Antiprotozoal Agents; Brazil; Cell Survival; Colorimetry; Gas Chromatography-Mass Spectrometry; Genotype; Humans; Inhibitory Concentration 50; Leishmania; Lippia; Oils, Volatile; Plant Extracts; Plant Leaves; Tetrazolium Salts; Thiazoles; Trichophyton | 2013 |
Bengalin initiates autophagic cell death through ERK-MAPK pathway following suppression of apoptosis in human leukemic U937 cells.
Topics: Apoptosis; Autophagy; Blotting, Western; Caspase 3; Cell Death; Chromatography, High Pressure Liquid; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Organelles; RNA, Small Interfering; Scorpion Venoms; Tetrazolium Salts; Thiazoles; U937 Cells | 2013 |
A uniaxial cell stretcher in vitro model simulating tissue expansion of plastic surgery.
Topics: Biomechanical Phenomena; Blotting, Western; Cell Culture Techniques; Cell Cycle Proteins; Cell Proliferation; Cell Shape; Cells, Cultured; Coloring Agents; Fibroblasts; Humans; Membranes, Artificial; Polymethyl Methacrylate; Proliferating Cell Nuclear Antigen; Silicone Elastomers; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Expansion | 2013 |
Knockdown of PLA2G2A sensitizes gastric cancer cells to 5-FU in vitro.
Topics: Animals; Antimetabolites; Apoptosis; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Genetic Vectors; Group II Phospholipases A2; Humans; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection | 2013 |
Propofol inhibits invasion and enhances paclitaxel- induced apoptosis in ovarian cancer cells through the suppression of the transcription factor slug.
Topics: Anesthetics, Intravenous; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; In Situ Nick-End Labeling; Neoplasm Invasiveness; Ovarian Neoplasms; Paclitaxel; Propofol; Snail Family Transcription Factors; Tetrazolium Salts; Thiazoles; Transcription Factors | 2013 |
Determining if low dose hyper-radiosensitivity (HRS) can be exploited to provide a therapeutic advantage: a cell line study in four glioblastoma multiforme (GBM) cell lines.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; DNA Repair; Dose Fractionation, Radiation; G2 Phase Cell Cycle Checkpoints; Glioblastoma; Humans; Models, Theoretical; Radiation Tolerance; Tetrazolium Salts; Thiazoles; X-Rays | 2013 |
Reactive oxygen species involvement in apoptosis and mitochondrial damage in Caco-2 cells induced by enniatins A, A₁, B and B₁.
Topics: Apoptosis; Caco-2 Cells; Cell Cycle; Cell Survival; Coloring Agents; Comet Assay; Depsipeptides; Flow Cytometry; Humans; Indicators and Reagents; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria; Organometallic Compounds; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2013 |
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death.
Topics: 4-Butyrolactone; Annexin A5; Apoptosis; BRCA2 Protein; Cell Death; Cell Line, Tumor; Cell Proliferation; Comet Assay; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; K562 Cells; Pyrones; Tetrazolium Salts; Thiazoles | 2013 |
Multi-platform genotoxicity analysis of silver nanoparticles in the model cell line CHO-K1.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Cell Cycle; CHO Cells; Coloring Agents; Cricetinae; Cricetulus; Deoxyguanosine; DNA Adducts; Flow Cytometry; Mass Spectrometry; Micronucleus Tests; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mutagenicity Tests; Mutagens; Nanoparticles; Necrosis; Reactive Oxygen Species; Silver; Tetrazolium Salts; Thiazoles | 2013 |
Functional regulatory role of STAT3 in HPV16-mediated cervical carcinogenesis.
Topics: Carcinogenesis; Caspase 3; Cell Line, Tumor; Curcumin; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Gene Expression Regulation, Viral; Human papillomavirus 16; Humans; Immunoblotting; Immunohistochemistry; Oncogene Proteins, Viral; RNA, Small Interfering; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tyrphostins; Uterine Cervical Neoplasms | 2013 |
Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Flow Cytometry; Humans; Indicators and Reagents; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Prostatic Neoplasms; Reactive Oxygen Species; Spleen; Tetrazolium Salts; Thiazoles; Vitamin K 3 | 2013 |
A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury.
Topics: Amides; Animals; Blotting, Western; Cell Survival; Coloring Agents; Cyclooxygenase 2; Drug Combinations; Endocannabinoids; Ethanolamines; Inflammation; Luteolin; Mice; Nanoparticles; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Organ Culture Techniques; Palmitic Acids; Pharmaceutical Solutions; Spinal Cord Injuries; Tetrazolium Salts; Thiazoles | 2013 |
Glycol chitin-based thermoresponsive hydrogel scaffold supplemented with enamel matrix derivative promotes odontogenic differentiation of human dental pulp cells.
Topics: Body Temperature; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Chitin; Collagen; Coloring Agents; Dental Enamel Proteins; Dental Pulp; Extracellular Matrix Proteins; Humans; Hydrogels; Microscopy, Electron, Scanning; Odontogenesis; Osteonectin; Osteopontin; Phase Transition; Phosphoproteins; Porosity; Rheology; Sialoglycoproteins; Stem Cells; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2013 |
Dermal cell damage induced by topical application of non-steroidal anti-inflammatory drugs is suppressed by trehalose co-lyophilization in ex vivo analysis.
Topics: Administration, Topical; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Freeze Drying; Humans; Rats; Skin; Tetrazolium Salts; Thiazoles; Trehalose | 2013 |
A cocaine-regulated and amphetamine-regulated transcript inhibits oxidative stress in neurons deprived of oxygen and glucose.
Topics: Animals; Apoptosis; Cell Hypoxia; Cerebral Cortex; Coloring Agents; Flow Cytometry; Glucose; Membrane Potential, Mitochondrial; Mice; Mitochondria; Nerve Tissue Proteins; Neurons; Oxidative Stress; Peptide Fragments; Primary Cell Culture; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Combined effect of PLGA and curcumin on wound healing activity.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Survival; Collagen; Curcumin; Female; Glutathione Peroxidase; Keratinocytes; L-Lactate Dehydrogenase; Lactic Acid; Mice; Nanoparticles; NF-kappa B; Peroxidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Tetrazolium Salts; Thiazoles; Wound Healing | 2013 |
Structure-activity relationships of saponins enhancing the cytotoxicity of ribosome-inactivating proteins type I (RIP-I).
Topics: Cell Line, Tumor; Colorimetry; Epithelial Cells; Fluorescence; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Ribosome Inactivating Proteins, Type 1; Saponins; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2013 |
Tetracycline-encapsulated P(3HB) microsphere-coated 45S5 Bioglass(®)-based scaffolds for bone tissue engineering.
Topics: Animals; Anti-Bacterial Agents; Bone and Bones; Bone Substitutes; Ceramics; Coated Materials, Biocompatible; Drug Carriers; Drug Delivery Systems; Fibroblasts; Glass; Materials Testing; Mice; Microspheres; Tetracycline; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2013 |
Additive effect of sirolimus and anti-death receptor 5 agonistic antibody against hepatocellular carcinoma.
Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sirolimus; Tetrazolium Salts; Thiazoles | 2013 |
Cellular toxicity and apoptosis studies in osteocarcinoma cells, a comparison of 177Lu-EDTMP and Lu-EDTMP.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Humans; L-Lactate Dehydrogenase; Organometallic Compounds; Organophosphorus Compounds; Osteosarcoma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Radionuclide Imaging; Radiopharmaceuticals; Tetrazolium Salts; Thiazoles; Trypan Blue | 2013 |
CHL1 is involved in human breast tumorigenesis and progression.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2013 |
Cylindroside A, a new triterpenoid saponin from Cylindrokelupha dalatensis and its cytotoxic activity.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; MCF-7 Cells; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Seeds; Tetrazolium Salts; Thiazoles; Triterpenes | 2013 |
Antibacterial and physical properties of EGCG-containing glass ionomer cements.
Topics: Anti-Bacterial Agents; Biofilms; Cariostatic Agents; Catechin; Chemical Phenomena; Chlorhexidine; Chromatography; Colorimetry; Coloring Agents; Dental Stress Analysis; Fluorides; Glass Ionomer Cements; Hardness; Humans; Light; Materials Testing; Microscopy, Electron, Scanning; Pliability; Spectrophotometry; Streptococcus mutans; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thiazoles | 2013 |
Mesoporous iron oxide nanoparticles prepared by polyacrylic acid etching and their application in gene delivery to mesenchymal stem cells.
Topics: Animals; Biocompatible Materials; Cell Survival; Ferric Compounds; Gene Transfer Techniques; Genes, Reporter; Green Fluorescent Proteins; Materials Testing; Mesenchymal Stem Cells; Microscopy, Electron; Nanoparticles; Rats; Recombinant Fusion Proteins; Staining and Labeling; Tetrazolium Salts; Thiazoles; Transfection; Vascular Endothelial Growth Factor A | 2013 |
Nanog attenuates lipopolysaccharide-induced inflammatory responses by blocking nuclear factor-κB transcriptional activity in BV-2 cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cytokines; Homeodomain Proteins; Inflammation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Mice; Nanog Homeobox Protein; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Plasmids; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2013 |
Magnesium-enhanced enzymatically mineralized platelet-rich fibrin for bone regeneration applications.
Topics: Alkaline Phosphatase; Biocompatible Materials; Bone Regeneration; Bone Substitutes; Cell Line, Tumor; Fibrin; Glycerophosphates; Humans; Hydrogels; Magnesium; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2013 |
Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cells.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cardiovascular Agents; Cell Line; Coloring Agents; Cytochromes c; Diosgenin; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2014 |
Hydrogen peroxide induces apoptosis in human dental pulp cells via caspase-9 dependent pathway.
Topics: Actins; Adolescent; Adult; Annexin A5; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dental Pulp; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Hydrogen Peroxide; Oxidants; Propidium; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2013 |
2-Hydroxyethyl methacrylate inhibits migration of dental pulp stem cells.
Topics: Blotting, Western; Cell Culture Techniques; Cell Movement; Cell Survival; Coloring Agents; Dental Materials; Dental Pulp; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Kinase 1; Glycogen Synthase Kinase 3; Humans; Imidazoles; MAP Kinase Signaling System; Methacrylates; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Stem Cells; Tetrazolium Salts; Thiazoles | 2013 |
PKCɛ mediates serine phosphorylation of connexin43 induced by lysophosphatidylcholine in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Survival; Coloring Agents; Connexin 43; Female; Fluorescent Antibody Technique; Heart Rate; Immunoprecipitation; Indoles; Lysophosphatidylcholines; Male; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles | 2013 |
Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice.
Topics: Animals; Apoptosis; Blotting, Western; Bone Marrow Cells; Cell Separation; Cell Survival; Coloring Agents; Culture Media, Conditioned; Dietary Fats; Fatty Acids; Glucose; Hepatocytes; In Situ Nick-End Labeling; Inflammation; Lipid Metabolism; Lipogenesis; Macrophages; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Triglycerides | 2013 |
B19, a novel monocarbonyl analogue of curcumin, induces human ovarian cancer cell apoptosis via activation of endoplasmic reticulum stress and the autophagy signaling pathway.
Topics: Analysis of Variance; Apoptosis; Autophagy; Blotting, Western; Cell Line, Tumor; Curcumin; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Microscopy, Electron; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Folic acid conjugated δ-valerolactone-poly(ethylene glycol) based triblock copolymer as a promising carrier for targeted doxorubicin delivery.
Topics: Annexin A5; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Esters; Female; Folic Acid; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Micelles; Polyethylene Glycols; Pyrones; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2013 |
Electrospun poly(L-lactide)/poly(ε-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells.
Topics: Adipocytes; Adipose Tissue; Adult; Animals; Biocompatible Materials; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Survival; Female; Humans; Immunohistochemistry; Male; Microscopy, Electron, Scanning; Nanofibers; Polyesters; Porosity; Rats; Rats, Sprague-Dawley; Regeneration; Spectroscopy, Fourier Transform Infrared; Stem Cells; Tensile Strength; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2013 |
RNA-mediated gene silencing of nicotinamide N-methyltransferase is associated with decreased tumorigenicity in human oral carcinoma cells.
Topics: Agar; Animals; Biomarkers, Tumor; Blotting, Western; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Female; Gene Silencing; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Nicotinamide N-Methyltransferase; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2013 |
Properties of a proline-containing glass ionomer dental cement.
Topics: Acrylic Resins; Adsorption; Animals; Cariostatic Agents; Cell Line; Cell Proliferation; Cell Survival; Chemical Phenomena; Coloring Agents; Diffusion; Fluorides; Glass Ionomer Cements; Hardness; Materials Testing; Mice; Molecular Weight; Muscle Cells; Proline; Succinates; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Viscosity; Water | 2013 |
Epidermal growth factor can optimize a serum-free culture system for bone marrow stem cell proliferation in a miniature pig model.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Proliferation; Culture Media, Serum-Free; DNA Primers; Dose-Response Relationship, Drug; Epidermal Growth Factor; Mesenchymal Stem Cells; Real-Time Polymerase Chain Reaction; Swine; Swine, Miniature; Tetrazolium Salts; Thiazoles | 2013 |
Sodium arsenite and arsenic trioxide differently affect the oxidative stress, genotoxicity and apoptosis in A549 cells: an implication for the paradoxical mechanism.
Topics: Annexin A5; Apoptosis; Arsenic Trioxide; Arsenicals; Arsenites; Cell Cycle; Cell Line, Tumor; Coloring Agents; Comet Assay; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; In Situ Nick-End Labeling; Micronucleus Tests; Mutagens; Oxidative Stress; Oxides; Reactive Oxygen Species; Sodium Compounds; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2013 |
Cytotoxic, pro-apoptotic, pro-oxidant, and non-genotoxic activities of a novel copper(II) complex against human cervical cancer.
Topics: Animals; Annexins; Apoptosis; Brain Chemistry; Caspase 3; Caspase 7; Cell Line, Tumor; Coloring Agents; Coordination Complexes; Copper; Cytochromes c; Cytosol; DNA Fragmentation; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; HeLa Cells; Humans; In Situ Nick-End Labeling; Lipid Peroxidation; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Oxidants; Phosphatidylserines; Rats; Salmonella typhimurium; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2013 |
Preparation and in vitro anti-tumor properties of toad venom extract-loaded solid lipid nanoparticles.
Topics: Administration, Intravaginal; Amphibian Venoms; Antineoplastic Agents; Cell Cycle; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Drug Design; Female; HeLa Cells; Humans; Microscopy, Electron, Transmission; Nanoparticles; Ovarian Neoplasms; Particle Size; Suspensions; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2013 |
Particle-size-dependent cytokine responses and cell damage induced by silica particles and macrophages-derived mediators in endothelial cell.
Topics: Cell Line; Cell Survival; Coloring Agents; Cytokines; Dust; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; L-Lactate Dehydrogenase; Macrophages; Particle Size; Silicon Dioxide; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2013 |
In vitro comparative assessment of different viability assays in Acanthamoeba castellanii and Acanthamoeba polyphaga trophozoites.
Topics: Acanthamoeba; Acanthamoeba castellanii; Acanthamoeba Keratitis; Antiprotozoal Agents; Chlorhexidine; Contact Lenses; Humans; Indicators and Reagents; Oxazines; Tetrazolium Salts; Thiazoles; Trophozoites; Xanthenes | 2013 |
Effects of COREXIT dispersants on cytotoxicity parameters in a cultured human bronchial airway cells, BEAS-2B.
Topics: Apoptosis; Autophagy; Bronchi; Caspase 3; Cell Line; Cell Survival; Coloring Agents; Environmental Restoration and Remediation; Humans; Oxidative Stress; Oxidoreductases; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Respiratory Mucosa; Surface-Active Agents; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 2013 |
Enhanced apoptotic effects of dihydroartemisinin-aggregated gelatin and hyaluronan nanoparticles on human lung cancer cells.
Topics: Absorbable Implants; Antineoplastic Agents, Phytogenic; Apoptosis; Artemisinins; Cell Line, Tumor; Cell Survival; Coloring Agents; Drug Carriers; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gelatin; Humans; Hyaluronic Acid; Lung Neoplasms; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Tetrazolium Salts; Thiazoles | 2014 |
Biocompatibility of a conventional glass ionomer, ceramic reinforced glass ionomer, giomer and resin composite to fibroblasts: in vitro study.
Topics: Animals; Biocompatible Materials; Cell Survival; Coloring Agents; Composite Resins; Dental Cements; Fibroblasts; Glass Ionomer Cements; L Cells; Mice; Resin Cements; Tetrazolium Salts; Thiazoles | 2013 |
Transferrin as a drug carrier: Cytotoxicity, cellular uptake and transport kinetics of doxorubicin transferrin conjugate in the human leukemia cells.
Topics: Algorithms; Antibiotics, Antineoplastic; Biological Transport, Active; Cell Line, Tumor; Cell Survival; Coloring Agents; Doxorubicin; Drug Carriers; Flow Cytometry; Humans; K562 Cells; Kinetics; Leukemia; Lymphocytes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transferrin | 2014 |
Cytotoxic properties of sunitinib and sorafenib on human corneal epithelial cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biomarkers; Cell Line; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Humans; Immunohistochemistry; Indoles; Membrane Proteins; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Neoplasm Proteins; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Sorafenib; Sunitinib; Tetrazolium Salts; Thiazoles | 2014 |
MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K.
Topics: Apoptosis; Computational Biology; Flow Cytometry; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Immunohistochemistry; Intervertebral Disc; Intervertebral Disc Degeneration; Luciferases; MicroRNAs; Phosphatidylinositol 3-Kinases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
Interleukin-13/Interleukin-4-induced oxidative stress contributes to death of prothrombinkringle-2 (pKr-2)-activated microglia.
Topics: Acetophenones; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebral Cortex; Cyclooxygenase 2; Enzyme Inhibitors; In Situ Nick-End Labeling; Interleukin-13; Interleukin-4; Kringles; Microglia; NADPH Oxidases; Nitrobenzenes; Oxidative Stress; Prothrombin; Rats; Sulfonamides; Tetrazolium Salts; Thiazoles | 2013 |
A small volatile bacterial molecule triggers mitochondrial dysfunction in murine skeletal muscle.
Topics: Acetophenones; Adenosine Triphosphate; Animals; Blotting, Western; Gene Expression Regulation; Humans; Insulin Resistance; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Microarray Analysis; Mitochondrial Diseases; Muscle, Skeletal; Pseudomonas aeruginosa; Quorum Sensing; Tetrazolium Salts; Thiazoles | 2013 |
Isoalantolactone inhibits UM-SCC-10A cell growth via cell cycle arrest and apoptosis induction.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin D; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; Head and Neck Neoplasms; Humans; Mitochondria; rho GTP-Binding Proteins; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2013 |
Edaravone protected human brain microvascular endothelial cells from methylglyoxal-induced injury by inhibiting AGEs/RAGE/oxidative stress.
Topics: Antipyrine; Blotting, Western; Brain; Diabetes Complications; Edaravone; Endothelial Cells; Glycation End Products, Advanced; Humans; Microvessels; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2013 |
Hypoxia pathways and cellular stress activate pancreatic stellate cells: development of an organotypic culture model of thick slices of normal human pancreas.
Topics: Apoptosis; Cell Differentiation; Cell Proliferation; Cellular Microenvironment; France; Humans; Hyperoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Pancreas; Pancreatic Stellate Cells; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Culture Techniques | 2013 |
Mechanism of cadmium induced apoptosis in human peripheral blood lymphocytes: the role of p53, Fas and Caspase-3.
Topics: Apoptosis; Cadmium; Caspase 3; Cell Death; Coloring Agents; DNA Fragmentation; fas Receptor; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Lymphocytes; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Suppressor Protein p53 | 2013 |
Screening and antiviral analysis of phages that display peptides with an affinity to subunit C of porcine aminopeptidase.
Topics: Amino Acid Sequence; Animals; Binding Sites; CD13 Antigens; Cell Surface Display Techniques; Enzyme-Linked Immunosorbent Assay; Gastroenteritis, Transmissible, of Swine; Male; Molecular Sequence Data; Oligopeptides; Peptide Library; Protein Subunits; Swine; Testis; Tetrazolium Salts; Thiazoles; Transmissible gastroenteritis virus; Virus Internalization | 2013 |
In-vitro analysis of rhBMP-2 effects in human osteogenic cells.
Topics: Adult; Blotting, Western; Bone Morphogenetic Protein 2; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Female; Fibronectins; Fluorescent Antibody Technique; Humans; Osteoblasts; Osteogenesis; Osteonectin; Osteopontin; Pregnancy; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tubulin | 2013 |
The influence of polymeric component of bioactive glass-based nanocomposite paste on its rheological behaviors and in vitro responses: hyaluronic acid versus sodium alginate.
Topics: Alginates; Alkaline Phosphatase; Animals; Apatites; Biocompatible Materials; Calcium; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Glass; Glucuronic Acid; Hexuronic Acids; Hyaluronic Acid; Injections; Materials Testing; Mice; Microscopy, Electron, Scanning; Nanocomposites; Polymers; Rheology; Silicones; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2014 |
Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells.
Topics: Acetylcholinesterase; Animals; Arsanilic Acid; Cell Differentiation; Embryonic Stem Cells; Environmental Pollutants; Fluorescent Antibody Technique; Fluoroquinolones; Gene Expression Regulation; Methylmercury Compounds; Mice; Nerve Tissue Proteins; Neurons; Tetrazolium Salts; Thiazoles | 2014 |
Regulation of matrix metalloproteinase-9 protein expression by 1α, 25-(OH)₂D₃ during osteoclast differentiation.
Topics: Acid Phosphatase; Animals; Blotting, Western; Calcitriol; Calcium Channel Agonists; Cell Differentiation; Cell Line; Cell Proliferation; Gene Expression Regulation, Enzymologic; Isoenzymes; Matrix Metalloproteinase 9; Mice; Osteoclasts; Tartrate-Resistant Acid Phosphatase; Tetrazolium Salts; Thiazoles | 2014 |
Preparation and degradation study of photocurable oligolactide-HA composite: a potential resin for stereolithography application.
Topics: Algorithms; Animals; Biodegradable Plastics; Cell Survival; Coloring Agents; Composite Resins; Dioxanes; Gels; Hot Temperature; Hyaluronic Acid; Magnetic Resonance Spectroscopy; Materials Testing; Mechanical Phenomena; Mice; Microscopy, Electron, Scanning; Molecular Weight; NIH 3T3 Cells; Tetrazolium Salts; Thermogravimetry; Thiazoles | 2014 |
Synergistic effect of static magnetic field and HA-Fe3O4 magnetic composites on viability of S. aureus and E. coli bacteria.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biocompatible Materials; Cell Membrane; Cell Membrane Permeability; Coloring Agents; Durapatite; Escherichia coli; Ferric Compounds; Magnetic Fields; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Reactive Oxygen Species; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2014 |
Chemotherapy stimulates syndecan-1 shedding: a potentially negative effect of treatment that may promote tumor relapse.
Topics: ADAM Proteins; Animals; Antineoplastic Agents; Blotting, Western; Bone Marrow; Caspase Inhibitors; DNA Primers; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Matrix Metalloproteinase Inhibitors; Mice; Multiple Myeloma; Real-Time Polymerase Chain Reaction; Recurrence; Syndecan-1; Tetrazolium Salts; Thiazoles; Tumor Microenvironment | 2014 |
Magnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Biphenyl Compounds; Bisbenzimidazole; Breast Neoplasms; Caspases; Cell Division; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cytochromes c; Female; Flow Cytometry; G2 Phase; Genes, bcl-2; Humans; Indicators and Reagents; Lignans; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2013 |
Borrelidin has limited anti-cancer effects in bcl-2 overexpressing breast cancer and leukemia cells and reveals toxicity in non-malignant breast epithelial cells.
Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; Blotting, Western; Breast; Breast Neoplasms; Cell Line, Tumor; Epithelial Cells; Fatty Alcohols; Female; Genes, bcl-2; Human Umbilical Vein Endothelial Cells; Humans; Leukemia; Tetrazolium Salts; Thiazoles | 2014 |
Platelet activating factor induces transient blood-brain barrier opening to facilitate edaravone penetration into the brain.
Topics: Animals; Antipyrine; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Blotting, Western; Brain; Brain Edema; Capillaries; Cerebrospinal Fluid; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Coloring Agents; E-Selectin; Edaravone; Endothelial Cells; Evans Blue; Flow Cytometry; Infusions, Intravenous; Male; Matrix Metalloproteinase 9; Microdialysis; Neuroprotective Agents; Platelet Activating Factor; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated; Tetrazolium Salts; Thiazoles | 2014 |
Liposomes as carriers of the lipid soluble antioxidant resveratrol: evaluation of amelioration of oxidative stress by additional antioxidant vitamin.
Topics: Amidines; Antioxidants; Area Under Curve; Ascorbic Acid; Cell Survival; Coloring Agents; Drug Carriers; Free Radical Scavengers; Humans; Indicators and Reagents; Leukocytes; Liposomes; Luminescence; Luminol; Oxidative Stress; Particle Size; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Vitamins | 2013 |
Photoswitchable nanoparticles for in vivo cancer chemotherapy.
Topics: Antineoplastic Agents; Benzopyrans; Drug Delivery Systems; HeLa Cells; Humans; Indoles; Nanoparticles; Neoplasms; Nitro Compounds; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays | 2013 |
Epstein-Barr Virus_Encoded LMP1 upregulates microRNA-21 to promote the resistance of nasopharyngeal carcinoma cells to cisplatin-induced Apoptosis by suppressing PDCD4 and Fas-L.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinoma; Cell Line; Cisplatin; Colony-Forming Units Assay; Drug Resistance, Neoplasm; Fas Ligand Protein; Fluorescent Antibody Technique; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Luciferases; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Viral Matrix Proteins | 2013 |
Effect of gold nanoparticles on photodynamic efficiency of 5-aminolevolenic acid photosensitiser in epidermal carcinoma cell line: an in vitro study.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Nanotechnology; Particle Size; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Tetrazolium Salts; Thiazoles | 2013 |
Sub-categorisation of skin corrosive chemicals by the EpiSkin™ reconstructed human epidermis skin corrosion test method according to UN GHS: revision of OECD Test Guideline 431.
Topics: Animal Testing Alternatives; Caustics; Coloring Agents; Epidermis; Guidelines as Topic; Humans; Reproducibility of Results; Skin Diseases; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles | 2014 |
Dieckol, a phlorotannin isolated from a brown seaweed, Ecklonia cava, inhibits adipogenesis through AMP-activated protein kinase (AMPK) activation in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Azo Compounds; Benzofurans; Blotting, Western; Cell Differentiation; Coloring Agents; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Freeze Drying; Mice; Phaeophyceae; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2013 |
A novel liposomal nanomedicine for nitric oxide delivery and breast cancer treatment.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Lipids; Liposomes; Mannitol; Nanoparticles; Nitric Oxide; Pressure; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Effects of ambroxol on Candida albicans growth and biofilm formation.
Topics: Ambroxol; Antifungal Agents; Biofilms; Candida albicans; Humans; Microbial Sensitivity Tests; Microbial Viability; Microscopy, Fluorescence; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2014 |
Effect of vasoactive intestinal peptide (VIP) on NKG2D signal pathway and its contribution to immune escape of MKN45 cells.
Topics: Analysis of Variance; Cell Line, Tumor; Cytotoxicity Tests, Immunologic; DNA Primers; Humans; Immunohistochemistry; Killer Cells, Natural; NF-kappa B; NK Cell Lectin-Like Receptor Subfamily K; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles; Tumor Escape; Vasoactive Intestinal Peptide | 2013 |
Boldine induces cell cycle arrest and apoptosis in T24 human bladder cancer cell line via regulation of ERK, AKT, and GSK-3β.
Topics: Antineoplastic Agents; Apoptosis; Aporphines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Peumus; Plant Extracts; Proto-Oncogene Proteins c-akt; Rhodamines; Signal Transduction; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms | 2014 |
Human epithelial tissue culture study on restorative materials.
Topics: Adolescent; Adult; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chromium Alloys; Coloring Agents; Dental Materials; Dental Porcelain; Epithelial Cells; Humans; Indicators and Reagents; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mouth Mucosa; Oxazines; Spectrometry, X-Ray Emission; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes; Young Adult; Yttrium; Zirconium | 2014 |
Construction and application of double-transfected cells expressing the human transporter P-glycoprotein and cytochrome P450 3A4.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cell Survival; Clone Cells; Coloring Agents; Cytochrome P-450 CYP3A; Dogs; Genetic Vectors; Humans; Plasmids; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles; Transfection | 2013 |
In vitro study of the cytotoxicities of two mixed-ligand oxovanadium complexes on human hepatoma cells.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Coloring Agents; Drug Screening Assays, Antitumor; Fluorescein-5-isothiocyanate; Fluorescent Dyes; G1 Phase; Humans; Liver Neoplasms, Experimental; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Organometallic Compounds; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Vanadium | 2013 |
Characterization of polyethylene glycol-polyethyleneimine as a vector for alpha-synuclein siRNA delivery to PC12 cells for Parkinson's disease.
Topics: alpha-Synuclein; Animals; Apoptosis; Cell Nucleus Shape; Cell Survival; Down-Regulation; Endosomes; Gene Transfer Techniques; Genetic Therapy; Intracellular Space; Neurotoxins; Parkinson Disease; Particle Size; PC12 Cells; Polyethylene Glycols; Polyethyleneimine; Rats; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2014 |
Protective effect of chlorophyllin and lycopene from water spinach extract on cytotoxicity and oxidative stress induced by heavy metals in human hepatoma cells.
Topics: Antioxidants; Carotenoids; Chlorophyllides; Chromatography, Liquid; Fluoresceins; Hep G2 Cells; Humans; Ipomoea; Lycopene; Metals; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2013 |
Anticancer metal complexes: synthesis and cytotoxicity evaluation by the MTT assay.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Colorimetry; Coloring Agents; Coordination Complexes; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Tetrazolium Salts; Thiazoles; Titanium; Vanadium | 2013 |
The inhibition effect of non-protein thiols on dentinal matrix metalloproteinase activity and HEMA cytotoxicity.
Topics: Acetylcysteine; Animals; Anti-Infective Agents, Local; Cell Line; Cell Survival; Chlorhexidine; Coloring Agents; Dental Materials; Dental Pulp; Dentin; Glutathione; Humans; Materials Testing; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Methacrylates; Phosphoric Acids; Rats; Tetrazolium Salts; Thiazoles | 2014 |
Palladium nanosheets as highly stable and effective contrast agents for in vivo photoacoustic molecular imaging.
Topics: Acoustics; Animals; Cell Line, Tumor; Cell Survival; Contrast Media; Gold; Metal Nanoparticles; Mice; Nanostructures; Neoplasm Transplantation; Neoplasms; Optics and Photonics; Palladium; Perfusion; Photochemistry; Tetrazolium Salts; Thiazoles; Tissue Distribution; Tomography; Transducers | 2014 |
Reversing P-glycoprotein-mediated multidrug resistance in vitro by α-asarone and β-asarone, bioactive cis-trans isomers from Acorus tatarinowii.
Topics: Acorus; Allylbenzene Derivatives; Anisoles; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Drug Resistance, Multiple; Epithelial Cells; Humans; Plant Extracts; Rhodamine 123; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2014 |
Ionic extraction of a novel nano-sized bioactive glass enhances differentiation and mineralization of human dental pulp cells.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anthraquinones; Calcification, Physiologic; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cells, Cultured; Ceramics; Chemical Fractionation; Collagen Type I; Coloring Agents; Dental Pulp; Extracellular Matrix Proteins; Glass; Humans; Nanoparticles; Odontogenesis; Osteocalcin; Particle Size; Phosphoproteins; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Young Adult | 2014 |
In vitro regulation of CCL3 and CXCL12 by bacterial by-products is dependent on site of origin of human oral fibroblasts.
Topics: Adolescent; Adult; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chemokine CCL3; Chemokine CXCL12; Child; Coloring Agents; Dental Pulp; Enterococcus faecalis; Escherichia coli; Fibroblasts; Gingiva; Humans; Lipopolysaccharides; MicroRNAs; Periodontal Ligament; Phenotype; Teichoic Acids; Tetrazolium Salts; Thiazoles; Tooth, Deciduous; Young Adult | 2014 |
Cytotoxicity evaluation of a new resin-based hybrid root canal sealer: an in vitro study.
Topics: Animals; Cell Count; Cell Death; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Composite Resins; Epoxy Resins; Fibroblasts; Materials Testing; Methacrylates; Mice; Neutral Red; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Humanin attenuated the change of voltage-dependent potassium currents in hippocampal neurons induced by anoxia.
Topics: Animals; Cell Hypoxia; Cell Survival; Cells, Cultured; Central Nervous System Agents; Dithionite; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Neurons; Neurotoxins; Patch-Clamp Techniques; Potassium; Potassium Channels, Voltage-Gated; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrazolium Salts; Tetrodotoxin; Thiazoles | 2014 |
Comparison of the cytotoxicity of high-level disinfectants by the MTT assay and direct contact assay.
Topics: Cell Adhesion; Cell Culture Techniques; Cell Survival; Disinfectants; Epithelial Cells; Equipment and Supplies; Glutaral; HeLa Cells; Humans; o-Phthalaldehyde; Peracetic Acid; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2013 |
Oral epithelial cell reaction after exposure to Invisalign plastic material.
Topics: Cell Adhesion; Cell Culture Techniques; Cell Death; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Movement; Cell Survival; Colorimetry; Coloring Agents; Culture Media; Dental Materials; Electric Impedance; Epithelial Cells; Flow Cytometry; Gingiva; Humans; Keratinocytes; Materials Testing; Orthodontic Appliances; Plastics; Polyurethanes; Saliva; Saliva, Artificial; Sodium Chloride; Tetrazolium Salts; Thiazoles; Time Factors; Tooth Movement Techniques | 2014 |
Exploring bioactive properties of marine cyanobacteria isolated from the Portuguese coast: high potential as a source of anticancer compounds.
Topics: Antineoplastic Agents; Atlantic Ocean; Biological Products; Cell Line, Tumor; Coloring Agents; Cyanobacteria; Drug Screening Assays, Antitumor; Humans; L-Lactate Dehydrogenase; Marine Toxins; Portugal; Species Specificity; Tetrazolium Salts; Thiazoles | 2013 |
Comparative characteristics of porous bioceramics for an osteogenic response in vitro and in vivo.
Topics: Adipose Tissue; Animals; Biocompatible Materials; Calcium Phosphates; Cell Culture Techniques; Ceramics; Culture Media; Durapatite; Immunoblotting; Immunohistochemistry; Mice; Osteoblasts; Osteogenesis; Porosity; Rabbits; Rats; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Atomic; Stem Cells; Tetrazolium Salts; Thiazoles | 2013 |
Ultrasound-triggered phase transition sensitive magnetic fluorescent nanodroplets as a multimodal imaging contrast agent in rat and mouse model.
Topics: Animals; Contrast Media; Fluorocarbons; Hemolysis; Mice; Microscopy, Electron, Transmission; Multimodal Imaging; Nanoparticles; Phase Transition; Rats; Tetrazolium Salts; Thiazoles; Ultrasonography | 2013 |
Bifunctional nanoparticles with magnetism and NIR fluorescence: controlled synthesis from combination of AGET ATRP and 'click' reaction.
Topics: Animals; Biocompatible Materials; Click Chemistry; Contrast Media; Dopamine; Epoxy Compounds; Female; Ferric Compounds; HeLa Cells; Humans; Iron; Magnetic Resonance Imaging; Magnetics; Metal Nanoparticles; Methacrylates; Mice; Mice, Nude; Microscopy, Confocal; Nanoparticles; Nanotechnology; Polyethylene Glycols; Polymethacrylic Acids; Silicon Dioxide; Solubility; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2014 |
Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Survival; Chick Embryo; Chorioallantoic Membrane; Coloring Agents; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiabendazole; Thiazoles; Vascular Endothelial Growth Factor A; Wound Healing | 2013 |
Induced marine fungus Chondrostereum sp. as a means of producing new sesquiterpenoids chondrosterins I and J by using glycerol as the carbon source.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Culture Media; Drug Screening Assays, Antitumor; Glycerol; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Polyporaceae; Sesquiterpenes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2014 |
Effects of different scaffolds on rat adipose tissue derived stroma cells.
Topics: Adipogenesis; Adipose Tissue; Animals; Biocompatible Materials; Bromodeoxyuridine; Cell Culture Techniques; Cell Differentiation; Cell Lineage; Cell Proliferation; Cell Survival; Chondrogenesis; Collagen; Coloring Agents; Fluorescent Dyes; Hyaluronic Acid; L-Lactate Dehydrogenase; Membranes, Artificial; Microscopy, Electron, Scanning; Osteogenesis; Rats; Stem Cells; Stromal Cells; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2014 |
Methylation of SFRP5 is related to multidrug resistance in leukemia cells.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; beta Catenin; Blotting, Western; Cell Line, Tumor; DNA Methylation; Doxorubicin; Drug Resistance, Multiple; Eye Proteins; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Leukemia; Membrane Proteins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Wnt Signaling Pathway | 2014 |
Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Disease-Free Survival; Endothelial Cells; Erythropoietin; Female; Gene Expression Regulation; Humans; Hypoxia; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplastic Stem Cells; Recurrence; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Effect of Biodentine™ on the proliferation, migration and adhesion of human dental pulp stem cells.
Topics: Adolescent; Adult; Biocompatible Materials; Bromodeoxyuridine; Calcium Compounds; Cell Adhesion; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chemokine CCL2; Chemokine CXCL12; Coloring Agents; Dental Cements; Dental Pulp; Fibroblast Growth Factor 2; Humans; Integrin beta1; Intercellular Adhesion Molecule-1; Materials Testing; Receptors, CXCR4; Silicates; Stem Cells; Tetrazolium Salts; Thiazoles; Vascular Cell Adhesion Molecule-1; Young Adult | 2014 |
Modified composites based on mesostructured iron oxyhydroxide and synthetic minerals: a potential material for the treatment of various toxic heavy metals and its toxicity.
Topics: Adsorption; Alginates; Cell Line; Cell Survival; Ferric Compounds; Humans; Indicators and Reagents; Kinetics; Metals, Heavy; Microscopy, Electron, Scanning; Minerals; Particle Size; Powders; Solutions; Tetrazolium Salts; Thermodynamics; Thiazoles; Water Pollutants, Chemical; X-Ray Diffraction; Zeolites | 2014 |
Preparation, blood coagulation and cell compatibility evaluation of chitosan-graft-polylactide copolymers.
Topics: Adsorption; Animals; Biocompatible Materials; Blood Coagulation; Carbodiimides; Cell Line; Cell Survival; Chitosan; Diffusion; Enzyme-Linked Immunosorbent Assay; Hemolysis; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Materials Testing; Methylamines; Mice; Polyesters; Succinimides; Tetrazolium Salts; Thiazoles | 2014 |
Alkaloids from the mangrove-derived actinomycete Jishengella endophytica 161111.
Topics: Actinobacteria; Alkaloids; Antiviral Agents; Chromatography, High Pressure Liquid; Coloring Agents; Fermentation; Humans; Influenza A Virus, H1N1 Subtype; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Roots; Rhizophoraceae; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2014 |
Generation and characterization of immortalized rat retinal microglial cell lines.
Topics: Animals; Animals, Newborn; Calcium-Binding Proteins; CD11b Antigen; Cell Line, Transformed; Cell Proliferation; Chemokine CCL2; Chemotaxis; Cytokines; Ectodysplasins; Gene Expression Regulation; Genetic Vectors; Microfilament Proteins; Microglia; Nitric Oxide; Phenotype; Rats; Rats, Sprague-Dawley; Retina; Tetrazolium Salts; Thiazoles; Transduction, Genetic | 2014 |
Anticancer activity of ferulic acid-inorganic nanohybrids synthesized via two different hybridization routes, reconstruction and exfoliation-reassembly.
Topics: Antineoplastic Agents; Coumaric Acids; HeLa Cells; Humans; Hydroxides; Nanostructures; Particle Size; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2013 |
A novel GuttaFlow sealer supports cell survival and attachment.
Topics: Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media; Dimethylpolysiloxanes; Drug Combinations; Epoxy Resins; Fibroblasts; Fluoresceins; Fluorescent Dyes; Gutta-Percha; Humans; Humidity; Materials Testing; Periodontal Ligament; Root Canal Filling Materials; Temperature; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
The role of integrin-α5 in the proliferation and odontogenic differentiation of human dental pulp stem cells.
Topics: Anthraquinones; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coloring Agents; Dental Pulp; Deoxyuridine; Extracellular Matrix Proteins; Gene Knockdown Techniques; Genetic Vectors; Humans; Integrin alpha5; Lentivirus; Odontogenesis; Phosphoproteins; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Sialoglycoproteins; Stem Cells; Tetrazolium Salts; Thiazoles | 2014 |
Radiopacity and cytotoxicity of Portland cement containing zirconia doped bismuth oxide radiopacifiers.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Biocompatible Materials; Bismuth; Calcium Compounds; Calcium Sulfate; Cell Survival; Ceramics; Coloring Agents; Contrast Media; Drug Combinations; Hot Temperature; Materials Testing; Mice; Osteoblasts; Oxides; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors; X-Ray Diffraction; Yttrium; Zirconium | 2014 |
Schisandra chinensis peptidoglycan-assisted transmembrane transport of lignans uniquely altered the pharmacokinetic and pharmacodynamic mechanisms in human HepG2 cell model.
Topics: Analysis of Variance; Biological Transport; Fruit; Hep G2 Cells; Humans; In Situ Nick-End Labeling; Lignans; Membrane Transport Modulators; Peptidoglycan; Plant Extracts; Schisandra; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2014 |
Evaluating the potential bioactivity of a novel compound ER1626.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Movement; Cell Proliferation; Chick Embryo; Endometrial Neoplasms; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Indenes; Isoquinolines; Ketones; MCF-7 Cells; Molecular Structure; Quinolones; Receptors, Estrogen; Tetrazolium Salts; Thiazoles | 2014 |
Oct4 mediates tumor initiating properties in oral squamous cell carcinomas through the regulation of epithelial-mesenchymal transition.
Topics: Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Primers; Epithelial-Mesenchymal Transition; Genetic Vectors; Humans; Mice; Mice, Nude; Mouth Neoplasms; Octamer Transcription Factor-3; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2014 |
Survival of neural stem cells undergoing DNA damage-induced astrocytic differentiation in self-renewal-promoting conditions in vitro.
Topics: Animals; Apoptosis; Astrocytes; Benzothiazoles; Cell Differentiation; Cell Survival; Diamines; DNA Breaks, Double-Stranded; DNA Primers; Mice; Microarray Analysis; Neural Stem Cells; Organic Chemicals; Quinolines; Tetrazolium Salts; Thiazoles | 2014 |
Response of human periodontal ligament cells to baicalin.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Female; Flavonoids; Gene Expression Regulation; Glucuronidase; Humans; Male; Osteocalcin; Osteoprotegerin; Periodontal Ligament; RANK Ligand; Real-Time Polymerase Chain Reaction; Scutellaria; Tetrazolium Salts; Thiazoles; Young Adult | 2014 |
Low toxic effects of a whitening strip to cultured pulp cells.
Topics: Animals; Cattle; Cell Culture Techniques; Cell Shape; Cell Survival; Coloring Agents; Dental Enamel Permeability; Dental Pulp; Dentin Permeability; Diffusion; Hydrogen Peroxide; Microscopy, Electron, Scanning; Odontoblasts; Saliva, Artificial; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Culture Techniques; Tooth Bleaching; Tooth Bleaching Agents | 2013 |
Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Hep G2 Cells; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Maleic Hydrazide; Organophosphorus Compounds; Plant Growth Regulators; Tetrazolium Salts; Thiazoles; Vero Cells | 2014 |
Cytotoxicity and enhancement activity of essential oil from Zanthoxylum bungeanum Maxim. as a natural transdermal penetration enhancer.
Topics: Administration, Cutaneous; Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Fluorouracil; Humans; Indomethacin; Inhibitory Concentration 50; Keratinocytes; Male; Oils, Volatile; Plant Oils; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Zanthoxylum | 2014 |
Mycotoxins' activity at toxic and sub-toxic concentrations: differential cytotoxic and genotoxic effects of single and combined administration of sterigmatocystin, ochratoxin A and citrinin on the hepatocellular cancer cell line Hep3B.
Topics: Cell Cycle; Cell Line, Tumor; Citrinin; Humans; Mitotic Index; Mutagenicity Tests; Ochratoxins; Sister Chromatid Exchange; Sterigmatocystin; Tetrazolium Salts; Thiazoles | 2014 |
Differential uptake of nanoparticles by endothelial cells through polyelectrolytes with affinity for caveolae.
Topics: Animals; Blotting, Western; Caveolae; Cell Line; Chemical Engineering; Drug Delivery Systems; Electrolytes; Endothelial Cells; Flow Cytometry; Fluorescent Antibody Technique; Humans; Mice; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Polymers; Real-Time Polymerase Chain Reaction; Static Electricity; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2014 |
Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids.
Topics: Acrolein; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cinnamomum zeylanicum; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Embryonic Stem Cells; Fibroblasts; Flavoring Agents; Gas Chromatography-Mass Spectrometry; Humans; Lung; Neural Stem Cells; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Tobacco Products | 2014 |
Differentially expressed genes and signalling pathways are involved in mouse osteoblast-like MC3T3-E1 cells exposed to 17-β estradiol.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Apoptosis; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Collagen; Coloring Agents; Cytokines; Estradiol; Estrogens; Gene Expression Profiling; Mice; Oligonucleotide Array Sequence Analysis; Osteoblasts; Signal Transduction; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 2014 |
Fucoidan reduces secretion and expression of vascular endothelial growth factor in the retinal pigment epithelium and reduces angiogenesis in vitro.
Topics: Antibodies, Monoclonal, Humanized; Bevacizumab; Cell Line; Collagen; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Immunohistochemistry; Laminin; Macular Degeneration; Microscopy, Confocal; Neovascularization, Physiologic; Polysaccharides; Proteoglycans; Retinal Pigment Epithelium; Tetrazolium Salts; Thiazoles; Trypan Blue; Vascular Endothelial Growth Factor A | 2014 |
Down-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathway.
Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytochromes c; DNA Primers; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitochondria; Nicotinamide N-Methyltransferase; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2014 |
Identification of microRNA-18a as a novel regulator of the insulin-like growth factor-1 in the proliferation and regeneration of deer antler.
Topics: 3' Untranslated Regions; Animals; Antlers; Blotting, Western; Cell Proliferation; Deer; Gene Expression Profiling; Gene Expression Regulation; Microarray Analysis; MicroRNAs; Real-Time Polymerase Chain Reaction; Regeneration; Somatomedins; Tetrazolium Salts; Thiazoles | 2014 |
Silicate esters of paclitaxel and docetaxel: synthesis, hydrophobicity, hydrolytic stability, cytotoxicity, and prodrug potential.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Coloring Agents; Docetaxel; Drug Delivery Systems; Drug Design; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Indicators and Reagents; Kinetics; Models, Molecular; Molecular Conformation; Nanoparticles; Paclitaxel; Prodrugs; Silicates; Taxoids; Tetrazolium Salts; Thiazoles | 2014 |
Regenerative capacity of human dental pulp and apical papilla cells after treatment with a 3-antibiotic mixture.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anthraquinones; Anti-Bacterial Agents; Calcification, Physiologic; Cell Culture Techniques; Cell Death; Cell Differentiation; Cell Proliferation; Cells, Cultured; Ciprofloxacin; Coloring Agents; Dental Papilla; Dental Pulp; Dentinogenesis; Extracellular Matrix Proteins; Humans; Integrin-Binding Sialoprotein; Metronidazole; Minocycline; Osteogenesis; Phosphoproteins; Regeneration; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2014 |
Antimicrobial activity and cytotoxicity of 3 photosensitizers activated with blue light.
Topics: Animals; Anti-Infective Agents; Cell Line; Cell Survival; Coloring Agents; Curcumin; Dental Pulp; Embryonic Stem Cells; Eosine Yellowish-(YS); Humans; Lactobacillus; Light; Mice; Microbial Viability; Mitochondria; Odontoblasts; Photosensitizing Agents; Rose Bengal; Tetrazolium Salts; Thiazoles | 2014 |
Cytotoxic and antimicrobial activities of Emex spinosa (L.) Campd. extract.
Topics: Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Coloring Agents; Drug Screening Assays, Antitumor; Egypt; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Extracts; Plant Leaves; Plant Roots; Polygonaceae; Tetrazolium Salts; Thiazoles | 2014 |
Resistance to mTOR kinase inhibitors in lymphoma cells lacking 4EBP1.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Benzoxazoles; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Drug Resistance; Gene Knockdown Techniques; Humans; Lymphoma; Phosphoproteins; Pyrimidines; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2014 |
Development and antimicrobial susceptibility studies of in vitro monomicrobial and polymicrobial biofilm models with Aspergillus fumigatus and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aspergillus fumigatus; Biofilms; Colony Count, Microbial; Microbial Sensitivity Tests; Microbial Viability; Microscopy; Pseudomonas aeruginosa; Spectrophotometry; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2014 |
The effect of ethylene oxide sterilization on the surface chemistry and in vitro cytotoxicity of several kinds of chitosan.
Topics: Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitin; Chitosan; Culture Media; Ethylene Oxide; Fourier Analysis; Humans; L-Lactate Dehydrogenase; Spectroscopy, Fourier Transform Infrared; Sterilization; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2013 |
Combination of dendrimer-nanovector-mediated small interfering RNA delivery to target Akt with the clinical anticancer drug paclitaxel for effective and potent anticancer activity in treating ovarian cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Death; Cells, Cultured; Coloring Agents; Dendrimers; Drug Delivery Systems; Female; Gene Silencing; Genetic Vectors; Humans; Mice; Mice, Nude; Models, Molecular; Nanotechnology; Nuclease Protection Assays; Oncogene Protein v-akt; Ovarian Neoplasms; Paclitaxel; Phosphatidylinositol 3-Kinases; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
Estrogen regulates the tumour suppressor MiRNA-30c and its target gene, MTA-1, in endometrial cancer.
Topics: Analysis of Variance; Blotting, Western; Cell Movement; DNA Primers; Endometrial Neoplasms; Estrogens; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; MicroRNAs; Real-Time Polymerase Chain Reaction; Repressor Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Trans-Activators | 2014 |
Near infrared radiation rescues mitochondrial dysfunction in cortical neurons after oxygen-glucose deprivation.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cerebral Cortex; Female; Glucose; Hypoxia, Brain; Infrared Rays; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondrial Diseases; Neurons; Primary Cell Culture; Tetrazolium Salts; Thiazoles | 2015 |
In vitro chemosensitivity assay of ascites in epithelial ovarian cancer.
Topics: Antineoplastic Agents; Ascites; Carboplatin; Carcinoma, Ovarian Epithelial; Coloring Agents; Deoxycytidine; Disease Progression; Drug Screening Assays, Antitumor; Epirubicin; Etoposide; Female; Fluorouracil; Gemcitabine; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Predictive Value of Tests; Retrospective Studies; Survival Rate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2013 |
Sinomenine reverses multidrug resistance in bladder cancer cells via P-glycoprotein-dependent and independent manners.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Coloring Agents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; Indicators and Reagents; Morphinans; Real-Time Polymerase Chain Reaction; Rhodamine 123; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms | 2014 |
Doxorubicin-conjugated PLA-PEG-Folate based polymeric micelle for tumor-targeted delivery: synthesis and in vitro evaluation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Micelles; Ovarian Neoplasms; Particle Size; Polyethylene Glycols; Tetrazolium Salts; Thiazoles | 2014 |
Validity of SW982 synovial cell line for studying the drugs against rheumatoid arthritis in fluvastatin-induced apoptosis signaling model.
Topics: Apoptosis; Arthritis, Rheumatoid; Cell Line; Cell Survival; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Membrane Potential, Mitochondrial; Polyisoprenyl Phosphates; Signal Transduction; Synovial Fluid; Tetrazolium Salts; Thiazoles | 2014 |
Interactions of manufactured silver nanoparticles of different sizes with normal human dermal fibroblasts.
Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Coloring Agents; Fibroblasts; Glutathione; Humans; L-Lactate Dehydrogenase; Metal Nanoparticles; Oxidative Stress; Particle Size; Reactive Oxygen Species; Silver Compounds; Skin; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2016 |
Anti-inflammatory potential of monogalactosyl diacylglycerols and a monoacylglycerol from the edible brown seaweed Fucus spiralis Linnaeus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Coloring Agents; Dexamethasone; Diglycerides; Enzyme Inhibitors; Fucus; Glycerides; Indicators and Reagents; L-Lactate Dehydrogenase; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2014 |
In vitro comparison of commercial oral rinses on bacterial adhesion and their detachment from biofilm formed on hydroxyapatite disks.
Topics: Actinomyces; Actinomyces viscosus; Anti-Infective Agents, Local; Bacterial Adhesion; Bacterial Load; Biofilms; Cells, Cultured; Cetylpyridinium; Chlorhexidine; Citrates; Coloring Agents; Dental Pellicle; Drug Combinations; Durapatite; Enterococcus faecalis; Epithelial Cells; Fusobacterium nucleatum; Humans; Hydrogen Peroxide; Materials Testing; Microbial Viability; Mouthwashes; Porphyromonas gingivalis; Streptococcus gordonii; Streptococcus mutans; Sulfates; Surface Properties; Tetrazolium Salts; Thiazoles; Zinc Compounds | 2014 |
CS5931, a novel polypeptide in Ciona savignyi, represses angiogenesis via inhibiting vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs).
Topics: Alkaline Phosphatase; Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Coloring Agents; Embryo, Nonmammalian; Female; Granulins; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Pregnancy; Real-Time Polymerase Chain Reaction; Recombinant Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles; Umbilical Cord; Urochordata; Vascular Endothelial Growth Factor A; Zebrafish | 2014 |
A novel electrochemical method to evaluate the cytotoxicity of heavy metals.
Topics: Cell Survival; Electrochemical Techniques; Electrodes; Graphite; HeLa Cells; Humans; Metals, Heavy; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2014 |
P21-driven multifusion gene system for evaluating the efficacy of histone deacetylase inhibitors by in vivo molecular imaging and for transcription targeting therapy of cancer mediated by histone deacetylase inhibitor.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Gene Fusion; Histone Deacetylase Inhibitors; Humans; Indicators and Reagents; Luciferases; Luminescence; Mice; Mice, Nude; Microscopy, Confocal; Molecular Imaging; Neoplasms; Plasmids; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transfection | 2014 |
Cyclooxygenase-2 inhibitor celecoxib suppresses invasion and migration of nasopharyngeal carcinoma cell lines through a decrease in matrix metalloproteinase-2 and -9 activity.
Topics: Carcinoma; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coloring Agents; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Indicators and Reagents; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrazoles; Sulfonamides; Tetrazolium Salts; Thiazoles; Wound Healing | 2014 |
The supercritical CO₂ extract from the skin of Bufo bufo gargarizans Cantor blocks hepatitis B virus antigen secretion in HepG2.2.15 cells.
Topics: Analysis of Variance; Animals; Antigens, Viral; Bufo bufo; Carbon Dioxide; Chromatography, High Pressure Liquid; DNA Primers; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Humans; Immunoenzyme Techniques; Real-Time Polymerase Chain Reaction; Skin; Tetrazolium Salts; Thiazoles; Tissue Extracts | 2014 |
Effect of bacterial growth period on the sensitivity of the MTT assay for silver.
Topics: Biological Assay; Oxygen Consumption; Rhizobium; Sensitivity and Specificity; Silver; Tetrazolium Salts; Thiazoles; Water Pollutants, Chemical | 2014 |
Bispidine analogues of cisplatin, carboplatin, and oxaliplatin. synthesis, structures, and cytotoxicity.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carboplatin; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; Humans; Models, Molecular; Molecular Conformation; Organoplatinum Compounds; Oxaliplatin; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2014 |
Setting time affects in vitro biological properties of root canal sealers.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Survival; Coloring Agents; Comet Assay; Composite Resins; Cricetinae; Cricetulus; Dental Cements; DNA Damage; Epoxy Resins; Fibroblasts; Materials Testing; Mutagens; Root Canal Filling Materials; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Streptococcus mutans biofilm formation and release of fluoride from experimental resin-based composites depending on surface treatment and S-PRG filler particle fraction.
Topics: Acrylic Resins; Biofilms; Biomass; Bisphenol A-Glycidyl Methacrylate; Cariostatic Agents; Coloring Agents; Composite Resins; Dental Enamel; Dental Materials; Dental Plaque; Dental Polishing; Diffusion; Fluorides; Light-Curing of Dental Adhesives; Materials Testing; Polyethylene Glycols; Polymethacrylic Acids; Saliva; Silicon Dioxide; Streptococcus mutans; Surface Properties; Surface Tension; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
A rapid thin-layer chromatography bioautographic method for detecting the monoamine oxidase inhibitors in plants.
Topics: Animals; Chromatography, Thin Layer; Drugs, Chinese Herbal; Fruit; Liquidambar; Liver; Male; Monoamine Oxidase Inhibitors; Plants, Medicinal; Rats; Rats, Wistar; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Tryptamines | 2014 |
Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner.
Topics: Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Methylation; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; HEK293 Cells; Histone Demethylases; Humans; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Snail Family Transcription Factors; Tetrazolium Salts; Thiazoles; Transcription Factors | 2014 |
Cytotoxicity of QMix™ endodontic irrigating solution on human bone marrow mesenchymal stem cells.
Topics: Acridine Orange; Biguanides; Cell Culture Techniques; Cell Death; Cell Line; Cell Membrane; Cell Shape; Cell Survival; Coloring Agents; Ethidium; Fluorescent Dyes; Humans; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Oxazines; Polymers; Root Canal Irrigants; Sodium Hypochlorite; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2014 |
The protective effects of erythropoietin on rat glomerular podocytes in culture are modulated by extracellular matrix proteins.
Topics: Animals; Cells, Cultured; Coloring Agents; Erythropoietin; Extracellular Matrix; Extracellular Matrix Proteins; Kidney Glomerulus; Podocytes; Primary Cell Culture; Rats; Receptors, Erythropoietin; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2013 |
Composition and biological activities of hogweed [Heracleum sphondylium L. subsp. ternatum (Velen.) Brummitt] essential oil and its main components octyl acetate and octyl butyrate.
Topics: Acetates; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Benzothiazoles; Biphenyl Compounds; Drug Screening Assays, Antitumor; Enterococcus faecalis; Escherichia coli; Fruit; Gas Chromatography-Mass Spectrometry; HCT116 Cells; Heracleum; Humans; Inhibitory Concentration 50; Italy; Microbial Sensitivity Tests; Molecular Structure; Oils, Volatile; Picrates; Pseudomonas aeruginosa; Staphylococcus aureus; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2014 |
Compounds used to produce cloned animals are genotoxic and mutagenic in mammalian assays in vitro and in vivo.
Topics: Adenine; Animals; Cell Culture Techniques; Cell Survival; Cloning, Organism; Coloring Agents; Comet Assay; Cycloheximide; Cytokinesis; Hep G2 Cells; Humans; Male; Mammals; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Nuclear Transfer Techniques; Tetrazolium Salts; Thiazoles; Trypan Blue | 2014 |
Syntheses of tanshinone anhydrides and their suppression on oxidized LDL uptake in macrophages and foam cell formation.
Topics: Abietanes; Anhydrides; Animals; Antineoplastic Agents, Phytogenic; Azo Compounds; Catalysis; Cell Line, Tumor; Cholesterol, LDL; Coloring Agents; Foam Cells; Indicators and Reagents; Lipoproteins, LDL; Macrophages; Magnetic Resonance Spectroscopy; Mice; Tetrazolium Salts; Thiazoles | 2014 |
Neuroprotective effects of ginsenoside Rg1 on oxygen-glucose deprivation reperfusion in PC12 cells.
Topics: Animals; Cell Hypoxia; Cell Survival; Coloring Agents; Ginsenosides; Glucose; Immunohistochemistry; In Situ Nick-End Labeling; Neuroprotective Agents; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles | 2014 |
Curcumin induces apoptosis via simultaneously targeting AKT/mTOR and RAF/MEK/ERK survival signaling pathways in human leukemia THP-1 cells.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Curcumin; Enzyme Activation; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Leukemia, Myeloid, Acute; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Oncogene Protein v-akt; raf Kinases; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2014 |
Effects of fluoroquinolone eye solutions without preservatives on human corneal epithelial cells in vitro.
Topics: Anti-Bacterial Agents; Cell Line; Cell Movement; Cell Survival; Epithelial Cells; Epithelium, Corneal; Fluoroquinolones; Humans; L-Lactate Dehydrogenase; Ophthalmic Solutions; Preservatives, Pharmaceutical; Tetrazolium Salts; Thiazoles | 2014 |
Comparison of some antioxidant properties of plant extracts from Origanum vulgare, Salvia officinalis, Eleutherococcus senticosus and Stevia rebaudiana.
Topics: Antioxidants; Cell Line, Tumor; Colorimetry; Drug Discovery; Eleutherococcus; Glutathione; Humans; Nitric Oxide; Origanum; Oxidation-Reduction; Phenols; Plant Extracts; Salvia officinalis; Stevia; Tetrazolium Salts; Thiazoles | 2014 |
Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia.
Topics: Breast Neoplasms; Cell Nucleus; Cell Proliferation; Cell Survival; Female; Fluorescent Dyes; Hot Temperature; Humans; Hyperthermia, Induced; MCF-7 Cells; Metal Nanoparticles; Microscopy, Confocal; Nanotechnology; Ribosomes; Tetrazolium Salts; Thiazoles | 2014 |
A TGF-β receptor 1 inhibitor for prevention of proliferative vitreoretinopathy.
Topics: Animals; Cell Proliferation; Cell Transdifferentiation; Disease Models, Animal; Fibroblasts; Humans; Intravitreal Injections; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Rabbits; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Retinal Pigment Epithelium; Tenon Capsule; Tetrazolium Salts; Thiazoles; Vitreoretinopathy, Proliferative | 2014 |
Biogenic silica-metal phosphate (metal = Ca, Fe or Zn) nanocomposites: fabrication from rice husk and their biomedical applications.
Topics: Bone and Bones; Calcium; Crystallization; Humans; Iron; Mesenchymal Stem Cells; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanocomposites; Nanotechnology; Oryza; Oxygen; Phosphates; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; X-Ray Diffraction; Zinc | 2014 |
LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G(2)/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo.
Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Coloring Agents; Flavonoids; Free Radical Scavengers; G2 Phase; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mitochondria; Reactive Oxygen Species; Signal Transduction; Subcellular Fractions; Tetrazolium Salts; Thiazoles | 2014 |
[Methotrexate as inducer of proinflammatory cytokines by epithelial cells].
Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Laryngeal Neoplasms; Methotrexate; Stomatitis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Arecoline is cytotoxic for human endothelial cells.
Topics: Arecoline; Autophagy; Cell Count; Cell Culture Techniques; Cell Survival; Cholinergic Agonists; Coloring Agents; Endoplasmic Reticulum; Fibroblasts; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Mitochondria; Mitochondrial Size; Necrosis; Oral Submucous Fibrosis; Ribosomes; Tetrazolium Salts; Thiazoles; Time Factors; Vacuoles | 2014 |
Synthesis of silver nanoparticles from Melia dubia leaf extract and their in vitro anticancer activity.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorocebus aethiops; Female; Green Chemistry Technology; Humans; MCF-7 Cells; Melia; Metal Nanoparticles; Microscopy, Electron, Scanning; Plant Extracts; Plant Leaves; Silver; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Vero Cells; X-Ray Diffraction | 2014 |
Oxidative damage repair by glutamine in fish enterocytes.
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Carps; Cell Proliferation; Cells, Cultured; Enterocytes; Glutamine; Hydrogen Peroxide; Oxidative Stress; Sodium-Potassium-Exchanging ATPase; Tetrazolium Salts; Thiazoles | 2014 |
Efficient gene carriers composed of 2-hydroxypropyl-β-cyclodextrin, ethanolamine-functionalized poly(glycidyl methacrylate), and poly((2-dimethyl amino)ethyl methacrylate) by combination of ATRP and click chemistry.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cell Survival; Chlorocebus aethiops; Click Chemistry; COS Cells; Electrophoretic Mobility Shift Assay; Ethanolamine; Genetic Vectors; Hep G2 Cells; Humans; Magnetic Resonance Spectroscopy; Methacrylates; Nylons; Plasmids; Polymerization; Polymethacrylic Acids; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
2,4-Dihydroxychalcone derivatives as novel potent cell division cycle 25B phosphatase inhibitors and protein tyrosine phosphatase 1B inhibitors.
Topics: Animals; Antineoplastic Agents; cdc25 Phosphatases; Cell Cycle; Cell Line, Tumor; Cell Survival; Chalcones; Coloring Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indicators and Reagents; Mice; Mice, Inbred BALB C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2014 |
Let-7 g microRNA sensitizes fluorouracil-resistant human hepatoma cells.
Topics: Antimetabolites, Antineoplastic; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Coloring Agents; Cyclin A; Down-Regulation; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Genetic Vectors; HMGA2 Protein; Humans; Liver Neoplasms; MicroRNAs; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
The suppressive role of SOX7 in hepatocarcinogenesis.
Topics: Blotting, Western; Carcinogenesis; Cell Line, Tumor; Colony-Forming Units Assay; DNA Primers; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Ki-67 Antigen; Liver Neoplasms; SOXF Transcription Factors; Tetrazolium Salts; Thiazoles | 2014 |
MicroRNA-21 regulates hTERT via PTEN in hypertrophic scar fibroblasts.
Topics: Blotting, Western; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Gene Expression Regulation; Humans; Immunohistochemistry; Luciferases; MicroRNAs; Oligonucleotides; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Signal Transduction; Telomerase; Tetrazolium Salts; Thiazoles | 2014 |
Netrin-1 ameliorates myocardial infarction-induced myocardial injury: mechanisms of action in rats and diabetic mice.
Topics: Analysis of Variance; Animals; Blotting, Western; DNA Primers; Genetic Vectors; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myocardial Infarction; Nerve Growth Factors; Netrin-1; Nitric Oxide; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2014 |
Cellular toxicity of calf blood extract on human corneal epithelial cells in vitro.
Topics: Actihaemyl; Animals; Cattle; Cell Line; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Epithelium, Corneal; Humans; L-Lactate Dehydrogenase; Microscopy, Phase-Contrast; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
Sensitive and selective determination of NO(2)(-) ion in aqueous samples using modified gold nanoparticle as a colorimetric probe.
Topics: Anions; Biosensing Techniques; Color; Colorimetry; Gold; Ions; Metal Nanoparticles; Nitrogen Dioxide; Particle Size; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Water; Water Pollutants, Chemical | 2014 |
The MEK1/2 inhibitor U0126 reverses imatinib resistance through down-regulating activation of Lyn/ERK signaling pathway in imatinib-resistant K562R leukemia cells.
Topics: Antineoplastic Agents; Benzamides; Blotting, Western; Butadienes; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Humans; Imatinib Mesylate; Indicators and Reagents; K562 Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Pyrimidines; Real-Time Polymerase Chain Reaction; src-Family Kinases; STAT5 Transcription Factor; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2014 |
Anticancer effects of celecoxib through inhibiton of STAT3 phosphorylation and AKT phosphorylation in nasopharyngeal carcinoma cell lines.
Topics: Antineoplastic Agents; Blotting, Western; Celecoxib; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclooxygenase 2 Inhibitors; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; STAT3 Transcription Factor; Sulfonamides; Tetrazolium Salts; Thiazoles | 2014 |
Necrosis factor-alpha (TNF-alpha) response in human hepatoma HepG2 cells treated with hepatotoxic agents.
Topics: Acetaldehyde; Acetaminophen; Cell Line; Cell Survival; Central Nervous System Depressants; Chemical and Drug Induced Liver Injury; Coloring Agents; Ethanol; Humans; Liver; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Ergosterol reverses multidrug resistance in SGC7901/Adr cells.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Coloring Agents; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ergosterol; Gene Expression Regulation, Neoplastic; Humans; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2014 |
Fluorescent dye labeled iron oxide/silica core/shell nanoparticle as a multimodal imaging probe.
Topics: Animals; Cell Survival; Contrast Media; Ferric Compounds; Fluorescent Dyes; HeLa Cells; Humans; Magnetic Resonance Imaging; Mice; Multimodal Imaging; Nanoparticles; Particle Size; Polyethylene Glycols; Silicon Dioxide; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2014 |
Cytotoxic and antigenotoxic activities of phosvitin from egg yolk.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chickens; DNA Damage; Dose-Response Relationship, Drug; Egg Yolk; HeLa Cells; Hep G2 Cells; Humans; Leukocytes, Mononuclear; MCF-7 Cells; Phosvitin; Tetrazolium Salts; Thiazoles | 2014 |
Rapid assays for lectin toxicity and binding changes that reflect altered glycosylation in mammalian cells.
Topics: Animals; Biological Assay; Cell Line; Cell Survival; CHO Cells; Coloring Agents; Cricetulus; Flow Cytometry; Glycoconjugates; Glycosylation; Lectins; Polysaccharides; Tetrazolium Salts; Thiazoles | 2014 |
Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders.
Topics: Animals; Behavior, Animal; Disks Large Homolog 4 Protein; Erythropoiesis; Female; Gene Expression Regulation; Gene Order; Gene Targeting; Glutamate Decarboxylase; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mental Disorders; Mice; Mice, Transgenic; Protein Biosynthesis; Quinone Reductases; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; RNA, Long Noncoding; Scotland; Tetrazolium Salts; Thiazoles; White People | 2014 |
Inosine strongly enhances proliferation of human C32 melanoma cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K pathways.
Topics: Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Humans; Inosine; Melanoma; Melanoma, Cutaneous Malignant; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Signal Transduction; Skin Neoplasms; Tetrazolium Salts; Thiazoles | 2015 |
A low cytotoxic cationic metal-organic framework carrier for controllable drug release.
Topics: Animals; Cations; Cell Survival; Drug Carriers; Drug Delivery Systems; Ferric Compounds; Ferrous Compounds; Ibuprofen; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles | 2014 |
miR-137 regulates the migration of human umbilical vein endothelial cells by targeting ephrin-type A receptor 7.
Topics: 3' Untranslated Regions; Binding Sites; Cell Movement; Cell Survival; Computational Biology; Gene Expression Regulation; Gene Targeting; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; Neovascularization, Pathologic; Neovascularization, Physiologic; Receptor, EphA7; Tetrazolium Salts; Thiazoles | 2014 |
Preparation and in vitro evaluation of strontium-doped calcium silicate/gypsum bioactive bone cement.
Topics: Absorbable Implants; Apatites; Biocompatible Materials; Bone Cements; Buffers; Calcium Compounds; Calcium Sulfate; Cell Proliferation; Cell Survival; Culture Media; Humans; Hydrogen-Ion Concentration; Ions; Materials Testing; Osteoblasts; Powders; Silicates; Stress, Mechanical; Strontium; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2014 |
An integrated study of natural hydroxyapatite-induced osteogenic differentiation of mesenchymal stem cells using transcriptomics, proteomics and microRNA analyses.
Topics: Alkaline Phosphatase; Animals; Bone Marrow Cells; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Durapatite; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Profiling; Gene Expression Regulation; Male; Mesenchymal Stem Cells; Mice; MicroRNAs; Microscopy, Electron, Scanning; Osteogenesis; Powders; Proteome; Proteomics; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Transcriptome | 2014 |
In vitro inhibition of the bovine viral diarrhoea virus by the essential oil of Ocimum basilicum (basil) and monoterpenes.
Topics: Antiviral Agents; Cell Survival; Colorimetry; Inhibitory Concentration 50; Microbial Sensitivity Tests; Monoterpenes; Ocimum basilicum; Oils, Volatile; Pestivirus; Plant Extracts; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Inactivation | 2014 |
Exposure of hepatocellular carcinoma cells to low-level As₂O₃ causes an extra toxicity pathway via L1 retrotransposition induction.
Topics: Animals; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Survival; Coloring Agents; Deoxyribonuclease I; DNA; Flow Cytometry; Green Fluorescent Proteins; Humans; Indicators and Reagents; Liver Neoplasms; Liver Neoplasms, Experimental; Microscopy, Fluorescence; Oxides; Plasmids; Real-Time Polymerase Chain Reaction; Retroelements; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
Perfluorooctanoic acid stimulates breast cancer cells invasion and up-regulates matrix metalloproteinase-2/-9 expression mediated by activating NF-κB.
Topics: Blotting, Western; Breast Neoplasms; Caprylates; Cell Line, Tumor; Coloring Agents; Female; Fluorocarbons; Humans; Indicators and Reagents; Luciferases; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Up-Regulation | 2014 |
Optimization of direct currents to enhance dentine bonding of simplified one-step adhesive.
Topics: Adolescent; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Composite Resins; Dental Bonding; Dental Leakage; Dental Materials; Dental Pulp; Dentin; Dentin-Bonding Agents; Electric Stimulation; Electricity; Electrochemical Techniques; Humans; Microscopy, Electron, Scanning; Resin Cements; Stress, Mechanical; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Piperazine designer drugs induce toxicity in cardiomyoblast h9c2 cells through mitochondrial impairment.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcium; Caspase 3; Cell Line; Cell Survival; Coloring Agents; Designer Drugs; Energy Metabolism; Flow Cytometry; Glutathione; Glutathione Reductase; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myoblasts, Cardiac; Necrosis; Neutral Red; Piperazines; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2014 |
Effects of the mycotoxin patulin at the level of nuclear receptor transcriptional activity and steroidogenesis in vitro.
Topics: Adrenal Glands; Cell Line; Cell Survival; Endocrine Disruptors; Estradiol; Genes, Reporter; Humans; In Vitro Techniques; Mycotoxins; Oxazines; Patulin; Progesterone; Receptors, Cytoplasmic and Nuclear; Testosterone; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Xanthenes | 2014 |
Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ.
Topics: Binding, Competitive; Carboxylic Acids; Cell Line; Cell Survival; Cells, Cultured; Circular Dichroism; Coloring Agents; Fluorocarbons; Humans; Models, Molecular; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Protein Binding; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
Real-time cell analysis: sensitivity of different vertebrate cell cultures to copper sulfate measured by xCELLigence(®).
Topics: Animals; Cell Survival; Cells, Cultured; Colorimetry; Copper Sulfate; Electric Impedance; Endpoint Determination; Humans; Mice; NIH 3T3 Cells; Oncorhynchus mykiss; Rats; Skin; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2014 |
Enhanced osteoblast proliferation and corrosion resistance of commercially pure titanium through surface nanostructuring by ultrasonic shot peening and stress relieving.
Topics: Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Proliferation; Coloring Agents; Corrosion; Crystallization; Dental Materials; Dental Polishing; Hot Temperature; Humans; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Nanostructures; Nitrites; Osteoblasts; Oxides; Potentiometry; Stainless Steel; Stress, Mechanical; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Titanium; Ultrasonics | 2014 |
In vitro toxicity of grey MTA in comparison to white MTA on human periodontal ligament fibroblasts.
Topics: Aluminum Compounds; Biocompatible Materials; Bismuth; Calcium Compounds; Cell Culture Techniques; Cell Survival; Cells, Cultured; Child; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Fibroblasts; Humans; Materials Testing; Oxides; Periodontal Ligament; Root Canal Filling Materials; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2014 |
Suppression of tumor growth by Pleurotus ferulae ethanol extract through induction of cell apoptosis, and inhibition of cell proliferation and migration.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Complex Mixtures; DNA Primers; Ethanol; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Medicine, Chinese Traditional; Mice; Neoplasm Invasiveness; Neoplasms; Pleurotus; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2014 |
The effects of caffeine on wound healing.
Topics: Caffeine; Cell Movement; Cell Proliferation; Humans; Keratinocytes; Tetrazolium Salts; Thiazoles; Wound Healing | 2016 |
Mechanisms of benzalkonium chloride toxicity in a human trabecular meshwork cell line and the protective role of preservative-free tafluprost.
Topics: Apoptosis; Benzalkonium Compounds; Cell Survival; Cells, Cultured; Connexin 43; Cytoprotection; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Microscopy, Confocal; Preservatives, Pharmaceutical; Prostaglandins F; Tetrazolium Salts; Thiazoles; Time Factors; Trabecular Meshwork | 2015 |
Rosmarinic acid mediated neuroprotective effects against H2O2-induced neuronal cell damage in N2A cells.
Topics: Animals; Antioxidants; Brain; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cinnamates; Comet Assay; Depsides; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Rosmarinic Acid; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2014 |
Effects of deferoxamine on the repair ability of dental pulp cells in vitro.
Topics: Adolescent; Alkaline Phosphatase; Calcification, Physiologic; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Deferoxamine; Dental Pulp; Fluorescent Dyes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Odontoblasts; Osteocalcin; Regeneration; Siderophores; Tetrazolium Salts; Thiazoles; Young Adult | 2014 |
Effects of SSd combined with radiation on inhibiting SMMC-7721 hepatoma cell growth.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; In Vitro Techniques; Liver Neoplasms; Microscopy, Electron, Transmission; Oleanolic Acid; Radiation-Sensitizing Agents; Saponins; Tetrazolium Salts; Thiazoles | 2014 |
Esculentin-1a(1-21)NH2: a frog skin-derived peptide for microbial keratitis.
Topics: Amphibian Proteins; Analysis of Variance; Animals; Antimicrobial Cationic Peptides; Anura; Contact Lenses; Cornea; Epithelial Cells; Humans; Keratitis; Pseudomonas aeruginosa; Skin; Tetrazolium Salts; Thiazoles | 2015 |
Experimental titanium alloys for dental applications.
Topics: Alloys; Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Dental Alloys; Dental Casting Technique; Dental Materials; Dental Stress Analysis; Elastic Modulus; Humans; Materials Testing; Mechanical Phenomena; Microscopy, Electron, Scanning; Plasma Gases; Pliability; Tantalum; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Titanium | 2014 |
Detection of increased 64Cu uptake by human copper transporter 1 gene overexpression using PET with 64CuCl2 in human breast cancer xenograft model.
Topics: Animals; Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Cisplatin; Copper; Copper Radioisotopes; Copper Transporter 1; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Kinetics; Mice; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2014 |
Conserved C-terminal nascent peptide binding domain of HYPK facilitates its chaperone-like activity.
Topics: Amino Acid Sequence; Carrier Proteins; Cluster Analysis; Conserved Sequence; DNA Primers; Humans; Microscopy, Confocal; Models, Genetic; Molecular Chaperones; Molecular Sequence Data; Phylogeny; Protein Conformation; Protein Structure, Tertiary; Sequence Analysis, Protein; Sequence Homology; Tetrazolium Salts; Thiazoles | 2014 |
Interfacial and biological properties of the gradient coating on polyamide substrate for bone substitute.
Topics: Animals; Bone Substitutes; Cell Adhesion; Durapatite; Materials Testing; Microscopy, Electron, Scanning; Nanostructures; Nylons; Osteoblasts; Porosity; Rabbits; Shear Strength; Spectrometry, X-Ray Emission; Surface Properties; Tetrazolium Salts; Thiazoles | 2014 |
[60]Fullerene derivative modulates adenosine and metabotropic glutamate receptors gene expression: a possible protective effect against hypoxia.
Topics: Adenosine; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Fullerenes; Gene Expression Regulation, Neoplastic; Humans; Protective Agents; Receptors, Metabotropic Glutamate; Tetrazolium Salts; Thiazoles | 2014 |
Cytotoxic constituents from the rhizomes of Curcuma zedoaria.
Topics: Analysis of Variance; Breast Neoplasms; Cell Proliferation; Chromatography, Thin Layer; Curcuma; Female; Human Umbilical Vein Endothelial Cells; Humans; Indonesia; Malaysia; MCF-7 Cells; Microscopy, Fluorescence; Molecular Structure; Phytotherapy; Plant Extracts; Rhizome; Tetrazolium Salts; Thiazoles | 2014 |
C-Myc participates in β-catenin-mediated drug resistance in A549/DDP lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Lung Neoplasms; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2014 |
Transport of ginkgolides with different lipophilicities based on an hCMEC/D3 cell monolayer as a blood-brain barrier cell model.
Topics: Analysis of Variance; Biological Transport; Blood-Brain Barrier; Cell Line; Chromatography, High Pressure Liquid; Ginkgo biloba; Ginkgolides; Humans; Molecular Structure; Plant Extracts; Tetrazolium Salts; Thiazoles | 2014 |
The influence of antibacterial toothpastes on in vitro Streptococcus mutans biofilm formation: a continuous culture study.
Topics: Adult; Anti-Bacterial Agents; Bacterial Load; Bacteriological Techniques; Biofilms; Biopsy; Cariostatic Agents; Coloring Agents; Dental Enamel; Diamines; Durapatite; Fluorides; Humans; Materials Testing; Microbial Viability; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Streptococcus mutans; Tetrazolium Salts; Thiazoles; Time Factors; Toothpastes; Triclosan | 2014 |
Cytotoxicity of four denture adhesives on human gingival fibroblast cells.
Topics: Adhesives; Apoptosis; Cell Culture Techniques; Cell Line; Cell Membrane; Cell Shape; Cell Survival; Denture Retention; Fibroblasts; Flow Cytometry; Gingiva; Humans; Maleates; Microscopy, Electron, Scanning; Polyethylenes; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
Hydroxyapatite and silk combination-coated dental implants result in superior bone formation in the peri-implant area compared with hydroxyapatite and collagen combination-coated implants.
Topics: Acid Etching, Dental; Aerosols; Alkaline Phosphatase; Animals; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Movement; Coated Materials, Biocompatible; Collagen Type I; Coloring Agents; Dental Implants; Dental Materials; Dental Prosthesis Design; Durapatite; Microscopy, Electron, Scanning; Osseointegration; Osteoblasts; Osteogenesis; Rabbits; Silk; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2014 |
Novel protein-repellent dental adhesive containing 2-methacryloyloxyethyl phosphorylcholine.
Topics: Adsorption; Bacterial Adhesion; Bacterial Load; Bacterial Proteins; Biofilms; Coloring Agents; Dental Bonding; Dental Plaque; Dentin; Humans; Indicators and Reagents; Materials Testing; Methacrylates; Microbial Viability; Phosphorylcholine; Quinolines; Resin Cements; Saliva; Shear Strength; Streptococcus mutans; Surface Properties; Tetrazolium Salts; Thiazoles | 2014 |
Dental pulp stem cells' secretome enhances pulp repair processes and compensates TEGDMA-induced cytotoxicity.
Topics: Adolescent; Anthraquinones; Autocrine Communication; Calcification, Physiologic; Cell Culture Techniques; Cell Movement; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Conditioned; Dental Materials; Dental Pulp; Fibroblast Growth Factor 2; Humans; Polyethylene Glycols; Polymethacrylic Acids; Stem Cells; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2014 |
In vitro biocompatibility, inflammatory response, and osteogenic potential of 4 root canal sealers: Sealapex, Sankin apatite root sealer, MTA Fillapex, and iRoot SP root canal sealer.
Topics: Alkaline Phosphatase; Aluminum Compounds; Anthraquinones; Biocompatible Materials; Calcium Compounds; Calcium Hydroxide; Cell Differentiation; Cell Line; Cell Survival; Coloring Agents; Drug Combinations; Durapatite; Focal Adhesion Kinase 1; Humans; Inflammation Mediators; Materials Testing; Mitogen-Activated Protein Kinases; Nanoparticles; NF-kappa B; Osteoblasts; Osteogenesis; Oxides; Paxillin; Periodontal Ligament; Proto-Oncogene Proteins c-akt; Root Canal Filling Materials; Salicylates; Signal Transduction; Silicates; Tetrazolium Salts; Thiazoles | 2014 |
New semi-biodegradable materials from semi-interpenetrated networks of poly(ϵ-caprolactone) and poly(ethyl acrylate).
Topics: Acrylic Resins; Animals; Biodegradable Plastics; Biotechnology; Calorimetry, Differential Scanning; Cell Line; Dioxanes; Immunohistochemistry; Mice; Microscopy, Electron, Scanning; Polyesters; Sheep; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tetrazolium Salts; Thermogravimetry; Thiazoles; Wettability | 2015 |
The effects of the natural enzyme, Pectinex Ultra SP-L, on human cell cultures and bacterial biofilms in vitro.
Topics: Adult; Anti-Bacterial Agents; Biofilms; Cell Culture Techniques; Cell Survival; Enzymes; HeLa Cells; Humans; Lymphocytes; Microbial Sensitivity Tests; Microbial Viability; Microscopy; Neutrophils; Pseudomonas aeruginosa; Spectrophotometry; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2014 |
MicroRNA-378 inhibits cell growth and enhances L-OHP-induced apoptosis in human colorectal cancer.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Computational Biology; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Kaplan-Meier Estimate; Luciferases; MicroRNAs; Organoplatinum Compounds; Oxaliplatin; Real-Time Polymerase Chain Reaction; RNA Splicing Factors; RNA-Binding Proteins; Tetrazolium Salts; Thiazoles | 2014 |
Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1 and AcrAP2, from the venom of the scorpion, Androctonus crassicauda, display potent growth modulation effects on human cancer cell lines.
Topics: Animals; Antimicrobial Cationic Peptides; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA Primers; DNA, Complementary; Drug Discovery; Hemolysis; Horses; Humans; Mass Spectrometry; Molecular Sequence Data; Scorpion Venoms; Tetrazolium Salts; Thiazoles | 2014 |
Membrane active phenylalanine conjugated lipophilic norspermidine derivatives with selective antibacterial activity.
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Drug Design; Drug Resistance, Bacterial; Enterococcus faecium; Humans; Kinetics; Klebsiella pneumoniae; Methicillin-Resistant Staphylococcus aureus; Micelles; Microbial Sensitivity Tests; Molecular Conformation; Phenylalanine; Plasma; Serum; Spermidine; Tetrazolium Salts; Thiazoles; Vancomycin | 2014 |
Cytotoxicity, DNA damage, and apoptosis induced by titanium dioxide nanoparticles in human non-small cell lung cancer A549 cells.
Topics: Analysis of Variance; Apoptosis; Carcinogens, Environmental; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Humans; Indoles; Metal Nanoparticles; Micronucleus Tests; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Titanium | 2015 |
Multiassay analysis of the toxic potential of hydrogen peroxide on cultured neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Extracellular Fluid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lactic Acid; Neurons; Oxidants; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2015 |
Protection or cytotoxicity mediated by a novel quinonoid-polyphenol compound?
Topics: Aging; Antioxidants; Apoptosis; Cells, Cultured; Flavonoids; Hormesis; Humans; Hydrogen Peroxide; Immunohistochemistry; Models, Molecular; Naphthoquinones; Necrosis; Neutral Red; Oxidants; Oxidative Stress; Polyphenols; Quinones; Tetrazolium Salts; Thiazoles | 2015 |
Role of resveratrol on the cytotoxic effects and DNA damages of iododeoxyuridine and megavoltage radiation in spheroid culture of U87MG glioblastoma cell line.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Glioblastoma; Humans; Idoxuridine; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Trypan Blue; X-Rays | 2015 |
β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.
Topics: Apoptosis; beta-Lactams; Cell Division; Chemistry, Pharmaceutical; Computer Simulation; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Estrogen Receptor beta; Estrogens; G2 Phase; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Ligands; MCF-7 Cells; Models, Molecular; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Software; Tetrazolium Salts; Thiazoles; Tubulin | 2014 |
Knockdown of EGFR inhibits growth and invasion of gastric cancer cells.
Topics: Blotting, Western; Cell Proliferation; ErbB Receptors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genetic Vectors; Humans; Immunohistochemistry; Lentivirus; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2014 |
Cell population kinetics of collagen scaffolds in ex vivo oral wound repair.
Topics: Becaplermin; Cell Count; Collagen; Connective Tissue Growth Factor; Cysteine-Rich Protein 61; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Gingiva; Humans; In Vitro Techniques; Integrin alpha2; Intercellular Signaling Peptides and Proteins; Microscopy, Electron, Scanning; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-sis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Tetrazolium Salts; Thiazoles; Tissue Scaffolds; Wound Healing | 2014 |
Effects of polychlorinated biphenyls 28, 30 and 118 on bovine spermatozoa in vitro.
Topics: Animals; Cattle; Cell Survival; Dose-Response Relationship, Drug; Endocrine Disruptors; Lethal Dose 50; Male; Polychlorinated Biphenyls; Semen Analysis; Sperm Motility; Spermatozoa; Tetrazolium Salts; Thiazoles | 2015 |
Design, synthesis and biological evaluation of nitro oxide donating N-hydroxycinnamamide derivatives as histone deacetylase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cinnamates; Drug Design; Drug Screening Assays, Antitumor; Free Radical Scavengers; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indicators and Reagents; Nitric Oxide Donors; Quantitative Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2014 |
Alternariol-induced cytotoxicity in Caco-2 cells. Protective effect of the phenolic fraction from virgin olive oil.
Topics: Analysis of Variance; Caco-2 Cells; Cell Proliferation; Humans; Lactones; Olive Oil; Phenols; Plant Extracts; Plant Oils; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2015 |
Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer.
Topics: Animals; Blotting, Western; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Diphosphonates; Drug Repositioning; ErbB Receptors; Female; Flow Cytometry; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Molecular Dynamics Simulation; Protein Binding; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2014 |
Bisphosphonates inactivate human EGFRs to exert antitumor actions.
Topics: Anisotropy; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Crystallography; Diphosphonates; ErbB Receptors; Fluorescence; Humans; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Tetrazolium Salts; Thiazoles | 2014 |
Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassays.
Topics: Androgen Antagonists; Cell Survival; Estrogen Receptor alpha; Estrogens, Non-Steroidal; Genes, Reporter; Humans; Luciferases; MCF-7 Cells; Receptors, Androgen; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Zearalenone | 2014 |
Induction of GADD45α protects M17 neuroblastoma cells against MPP*.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Anthracenes; Blotting, Western; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Imidazoles; In Situ Nick-End Labeling; Nuclear Proteins; Parkinson Disease; Pyridines; Real-Time Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles | 2014 |
Liposomes and MTT cell viability assay: an incompatible affair.
Topics: Biological Assay; Cell Survival; Formazans; HeLa Cells; Humans; Liposomes; Tetrazolium Salts; Thiazoles | 2015 |
Diosmin induces genotoxicity and apoptosis in DU145 prostate cancer cell line.
Topics: Apoptosis; Bromodeoxyuridine; Cell Line, Tumor; Comet Assay; Diosmin; DNA Methylation; Humans; Male; Membrane Potential, Mitochondrial; Micronucleus Tests; Mutagens; Oxidative Stress; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles | 2015 |
Mechanisms of cell death induced by infusion sets leachables in in vitro experimental settings.
Topics: Animals; Caspase 3; Caspase 7; Cell Death; Cell Line; Cell Membrane Permeability; Cell Survival; Disposable Equipment; Endothelial Cells; Fibroblasts; Infusions, Intravenous; Mice; Rubber; Tetrazolium Salts; Thiazoles | 2015 |
Uric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4.
Topics: Analysis of Variance; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Kidney Tubules, Proximal; Male; Mitochondrial Membranes; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Uric Acid | 2014 |
In vitro antimicrobial activities of 1-methoxyficifolinol, licorisoflavan A, and 6,8-diprenylgenistein against Streptococcus mutans.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Benzofurans; Benzopyrans; Biofilms; Chlorhexidine; Fibroblasts; Flavonoids; Genistein; Gentian Violet; Gingiva; Glycyrrhiza uralensis; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Confocal; Plant Extracts; Plant Roots; Streptococcus mutans; Streptococcus sobrinus; Tetrazolium Salts; Thiazoles | 2015 |
Evaluation of antileishmanial activity and cytotoxicity of the extracts of Berberis vulgaris and Nigella sativa against Leishmania tropica.
Topics: Animals; Antiprotozoal Agents; Berberis; Cell Survival; Cells, Cultured; Colorimetry; Inhibitory Concentration 50; Leishmania tropica; Macrophages; Male; Mice, Inbred BALB C; Nigella sativa; Plant Extracts; Staining and Labeling; Survival Analysis; Tetrazolium Salts; Thiazoles | 2014 |
Coenzyme Q10 protects astrocytes from ROS-induced damage through inhibition of mitochondria-mediated cell death pathway.
Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Cell Respiration; Cell Survival; Dose-Response Relationship, Drug; Immunohistochemistry; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors; Ubiquinone; Ultraviolet Rays | 2015 |
Directed interactions of block copolypept(o)ides with mannose-binding receptors: PeptoMicelles targeted to cells of the innate immune system.
Topics: Anhydrides; Animals; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Dendritic Cells; Drug Delivery Systems; Immunity, Innate; Immunomodulation; Magnetic Resonance Spectroscopy; Mannose-Binding Lectin; Mice; Micelles; Nanomedicine; Peptides; Sarcosine; Tetrazolium Salts; Thiazoles | 2015 |
An in vitro evaluation of the cytotoxicity of varying concentrations of sodium hypochlorite on human mesenchymal stem cells.
Topics: Acridine Orange; Cell Culture Techniques; Cell Death; Cell Line; Cell Shape; Cell Survival; Coloring Agents; Ethidium; Fluorescent Dyes; Humans; Indicators and Reagents; Materials Testing; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Oxazines; Root Canal Irrigants; Sodium Hypochlorite; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2014 |
eIF2 kinases mediate β-lapachone toxicity in yeast and human cancer cells.
Topics: Antineoplastic Agents; Dicumarol; eIF-2 Kinase; Enzyme Activation; Humans; Immunoblotting; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Oligonucleotide Array Sequence Analysis; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA, Small Interfering; Saccharomyces cerevisiae Proteins; Saccharomycetales; Tetrazolium Salts; Thiazoles; Transcriptome | 2015 |
Radiosensitization to X-ray radiation by telomerase inhibitor MST-312 in human hepatoma HepG2 cells.
Topics: Analysis of Variance; Apoptosis; Benzamides; Benzimidazoles; Bisbenzimidazole; Blotting, Western; Carbocyanines; Cell Proliferation; DNA Damage; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Hep G2 Cells; Humans; Membrane Potential, Mitochondrial; Radiation-Sensitizing Agents; Real-Time Polymerase Chain Reaction; Telomerase; Tetrazolium Salts; Thiazoles; X-Rays | 2015 |
Effect of organic-ligands on the toxicity profiles of CdS nanoparticles and functional properties.
Topics: Animals; Cadmium Compounds; Cell Survival; Chlorocebus aethiops; Cysteine; Dose-Response Relationship, Drug; Ligands; Nanoparticles; Particle Size; Povidone; Structure-Activity Relationship; Sulfides; Surface Properties; Tetrazolium Salts; Thiazoles; Vero Cells | 2015 |
High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis.
Topics: Alendronate; Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Clodronic Acid; Coloring Agents; Diphosphonates; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Humans; Ibandronic Acid; Necrosis; Osteoblasts; Pamidronate; Resting Phase, Cell Cycle; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
Glycolytic inhibitors 2-deoxyglucose and 3-bromopyruvate synergize with photodynamic therapy respectively to inhibit cell migration.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Deoxyglucose; Drug Synergism; Fluorescent Antibody Technique; Glycolysis; Humans; Microscopy, Electron, Scanning; Photochemotherapy; Pyruvates; Tetrazolium Salts; Thiazoles; Triple Negative Breast Neoplasms | 2015 |
MicroRNA-410 functions as a tumor suppressor by targeting angiotensin II type 1 receptor in pancreatic cancer.
Topics: Animals; Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Primers; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; MAP Kinase Signaling System; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Oligonucleotides, Antisense; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Wound Healing | 2015 |
Micheliolide derivative DMAMCL inhibits glioma cell growth in vitro and in vivo.
Topics: Analysis of Variance; Animals; Brain; Cell Line; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Glioma; Inhibitory Concentration 50; Molecular Structure; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes, Guaiane; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles | 2015 |
Biochemical characterization and antioxidant and antiproliferative activities of different Ganoderma collections.
Topics: Antineoplastic Agents; Antioxidants; Cell Line; Chromatography, High Pressure Liquid; Cluster Analysis; DNA, Fungal; DNA, Ribosomal Spacer; Flavonoids; Formazans; Ganoderma; Humans; Molecular Sequence Data; Monocytes; Mycological Typing Techniques; Phylogeny; Proteome; Sequence Analysis, DNA; Tetrazolium Salts; Thiazoles | 2015 |
An in vitro comparison of the cytotoxic potential of selected dehydropyrrolizidine alkaloids and some N-oxides.
Topics: Animals; Cattle; Cell Line, Tumor; Cell Survival; Chickens; Cyclic N-Oxides; Cytotoxins; HEK293 Cells; Hep G2 Cells; Humans; In Vitro Techniques; Molecular Structure; Monocrotaline; Pilot Projects; Pyrrolizidine Alkaloids; Tetrazolium Salts; Thiazoles | 2015 |
A fast Resazurin-based live viability assay is equivalent to the MTT-test in the KeratinoSens assay.
Topics: Animal Testing Alternatives; Cell Survival; Dose-Response Relationship, Drug; False Positive Reactions; Genes, Reporter; Humans; Indicators and Reagents; Irritants; Oxazines; Skin Diseases; Tetrazolium Salts; Thiazoles; Toxicity Tests; Xanthenes | 2015 |
[Effects of biogenic and abiogenic disulphides upon endothelial cells in culture: comparison of three methods of viability assessment].
Topics: Adenosine Triphosphate; Allyl Compounds; Artifacts; Cell Membrane; Cell Survival; Diethylamines; Disulfides; Glutathione Disulfide; Human Umbilical Vein Endothelial Cells; Humans; Neutral Red; Oxidation-Reduction; Oxidoreductases; Sulfides; Tetrazolium Salts; Thiazoles | 2014 |
Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals.
Topics: Animal Testing Alternatives; Chromatography, High Pressure Liquid; Coloring Agents; Cosmetics; Eye Diseases; Formazans; Humans; Irritants; Reproducibility of Results; Skin Diseases; Skin Irritancy Tests; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2015 |
Cytotoxicity of elastomeric power chains in artificial saliva: an in vitro study.
Topics: Cell Line, Tumor; Cell Survival; Coloring Agents; Culture Media, Conditioned; Dental Materials; Elasticity; Elastomers; Humans; Hydrogen-Ion Concentration; Immersion; Materials Testing; Orthodontic Appliances; Polyurethanes; Saliva, Artificial; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Autophagy; BH3 Interacting Domain Death Agonist Protein; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cytochromes c; Humans; Indoles; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Mitochondria; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Wasabia; Xenograft Model Antitumor Assays | 2016 |
Diospyros perigrena bark extract induced apoptosis in filarial parasite Setaria cervi through generation of reactive oxygen species.
Topics: 1-Butanol; Animals; Apoptosis; Bisbenzimidazole; Coloring Agents; Diospyros; DNA; Filariasis; Filaricides; In Situ Nick-End Labeling; Plant Bark; Plant Extracts; Reactive Oxygen Species; Setaria Nematode; Solvents; Tetrazolium Salts; Thiazoles | 2015 |
Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells.
Topics: Apoptosis; Cameroon; Cell Proliferation; Chromatography, High Pressure Liquid; Flow Cytometry; Fruit; G1 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Inhibitory Concentration 50; Mass Spectrometry; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Plant Bark; Plant Extracts; Polyphenols; Reactive Oxygen Species; Spices; Tetrazolium Salts; Thiazoles; Zanthoxylum | 2014 |
The protective effect of pyrimidine nucleosides on human HaCaT keratinocytes treated with 5-FU.
Topics: Antimetabolites, Antineoplastic; Cells, Cultured; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Keratinocytes; Pyrimidine Nucleosides; Tetrazolium Salts; Thiazoles; Thymidylate Synthase | 2015 |
A new indole-alkaloid and a new phenolic-glycoside with cytotoxic activity from Strychnos fendleri.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glycosides; Humans; Indoles; Magnetic Resonance Spectroscopy; Phenols; Plant Bark; Plant Extracts; Plant Leaves; Strychnos; Tetrazolium Salts; Thiazoles | 2016 |
Nano-Targeted Delivery of Toremifene, an Estrogen Receptor-α Blocker in Prostate Cancer.
Topics: Animals; Antineoplastic Agents, Hormonal; Cell Differentiation; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Delivery Systems; Estrogen Receptor alpha; Humans; Male; Mice; Mice, Nude; Necrosis; Particle Size; Prostate-Specific Antigen; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tissue Distribution; Toremifene | 2015 |
Role of the luxS gene in initial biofilm formation by Streptococcus mutans.
Topics: Bacterial Adhesion; Bacterial Proteins; Biofilms; Carbon-Sulfur Lyases; Gene Deletion; Gene Expression Profiling; Hydrophobic and Hydrophilic Interactions; Microscopy, Confocal; Staining and Labeling; Streptococcus mutans; Tetrazolium Salts; Thiazoles | 2015 |
Effect of sample preparation on components and liver toxicity of Polygonum multiflorum.
Topics: Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Ethanol; Hepatocytes; Humans; Limit of Detection; Plant Extracts; Polygonum; Reproducibility of Results; Solvents; Tetrazolium Salts; Thiazoles; Water | 2015 |
Effect of fatty acids on human bone marrow mesenchymal stem cell energy metabolism and survival.
Topics: Analysis of Variance; Blotting, Western; Cell Differentiation; Cell Proliferation; Energy Metabolism; Fatty Acids; Fluorescent Antibody Technique; Glycolysis; Humans; Mesenchymal Stem Cells; Mitochondria; Oxidation-Reduction; Palmitates; Tetrazolium Salts; Thiazoles | 2015 |
Effects of silver and gold nanoparticles of different sizes in human pulmonary fibroblasts.
Topics: Acetylcysteine; Antioxidants; Cardiotonic Agents; Cells, Cultured; Fibroblasts; Gold; Humans; Lung; Metal Nanoparticles; Oxidative Stress; Particle Size; Reactive Oxygen Species; Silver; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2015 |
Characterization of potent fusion inhibitors of influenza virus.
Topics: Animals; Dogs; Electrophoresis, Polyacrylamide Gel; Fluorescence; HeLa Cells; Humans; Hydrogen-Ion Concentration; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Microscopy, Electron; Norbornanes; Tetrazolium Salts; Thiazoles; Thiazolidines; Trypsin; Viral Fusion Protein Inhibitors; Viral Plaque Assay; Virion; Virus Internalization | 2015 |
The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides.
Topics: Analysis of Variance; Antineoplastic Agents; Carbon; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Decanoic Acids; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Peptides; Polyhydroxyalkanoates; Regression Analysis; Tetrazolium Salts; Thiazoles | 2015 |
Sodium nitrite provides angiogenic and proliferative effects in vivo and in vitro.
Topics: Animals; Cell Proliferation; Cell Survival; Chick Embryo; Chorioallantoic Membrane; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Neovascularization, Physiologic; Sodium Nitrite; Tetrazolium Salts; Thiazoles; Time Factors | 2015 |
Intracellular EP2 prostanoid receptor promotes cancer-related phenotypes in PC3 cells.
Topics: Analysis of Variance; Blotting, Western; Bromodeoxyuridine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Neovascularization, Pathologic; Phenotype; Prostatic Neoplasms; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Tetrazolium Salts; Thiazoles | 2015 |
Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma.
Topics: Analysis of Variance; APOBEC-1 Deaminase; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; China; Class I Phosphatidylinositol 3-Kinases; CREB-Binding Protein; Cytidine Deaminase; DNA Copy Number Variations; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Gene Knockdown Techniques; Genetic Predisposition to Disease; Genome, Human; Humans; Immunoblotting; Immunohistochemistry; In Situ Hybridization, Fluorescence; Ligases; LIM Domain Proteins; Molecular Sequence Data; Mutation; Patched Receptors; Patched-1 Receptor; Phosphatidylinositol 3-Kinases; Polycomb Repressive Complex 1; Polycomb-Group Proteins; Real-Time Polymerase Chain Reaction; Receptors, Cell Surface; Sequence Analysis, DNA; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Ubiquitin-Protein Ligases | 2015 |
Transcriptional profile of the human pathogenic fungus Paracoccidioides lutzii in response to sulfamethoxazole.
Topics: Anti-Infective Agents; Expressed Sequence Tags; Gene Expression Profiling; Gene Expression Regulation, Fungal; Metabolic Networks and Pathways; Microbial Viability; Mitochondria; Oxidation-Reduction; Paracoccidioides; Real-Time Polymerase Chain Reaction; Sulfamethoxazole; Tetrazolium Salts; Thiazoles | 2015 |
Mechanical Force-induced TGFB1 Increases Expression of SOST/POSTN by hPDL Cells.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Benzamides; Biomechanical Phenomena; Blotting, Western; Bone Morphogenetic Proteins; Cell Adhesion Molecules; Cell Culture Techniques; Cells, Cultured; Coloring Agents; Dioxoles; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Genetic Markers; Humans; Mechanotransduction, Cellular; Periodontal Ligament; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta1; Young Adult | 2015 |
Chemical characterisation of the coarse and fine particulate matter in the environment of an underground railway system: cytotoxic effects and oxidative stress-a preliminary study.
Topics: Air Pollutants; Air Pollution, Indoor; Cell Line, Tumor; Cell Survival; Humans; Italy; Metals; Oxidative Stress; Particle Size; Particulate Matter; Railroads; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2015 |
The surfactant dipalmitoylphophatidylcholine modifies acute responses in alveolar carcinoma cells in response to low-dose silver nanoparticle exposure.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adenocarcinoma, Bronchiolo-Alveolar; Cell Line, Tumor; Cell Survival; Coloring Agents; Humans; Inflammation; Lung Neoplasms; Metal Nanoparticles; Oxazines; Reactive Oxygen Species; Silver; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Xanthenes | 2015 |
Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays.
Topics: Artifacts; Biological Assay; Cell Count; Cell Line, Tumor; Cell Survival; Deoxyglucose; Glycolysis; Humans; Indazoles; Neutral Red; Observer Variation; Oxazines; Oxidation-Reduction; Pyruvates; Reproducibility of Results; Rhodamines; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Xanthenes | 2015 |
Diketopiperazines, inhibitors of sterol O-acyltransferase, produced by a marine-derived Nocardiopsis sp. KM2-16.
Topics: Actinomycetales; Animals; CHO Cells; Cricetinae; Cricetulus; Diketopiperazines; Endoplasmic Reticulum; Enzyme Inhibitors; Molecular Conformation; Sterol O-Acyltransferase; Tetrazolium Salts; Thiazoles | 2015 |
miR-128 modulates chemosensitivity and invasion of prostate cancer cells through targeting ZEB1.
Topics: Antineoplastic Agents; Blotting, Western; Coloring Agents; Disease Progression; Down-Regulation; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Immunoprecipitation; Male; MicroRNAs; Neoplasm Invasiveness; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques; Transcription Factors; Zinc Finger E-box-Binding Homeobox 1; Zinc Fingers | 2015 |
Protective effect of sulfurous water in peripheral blood mononuclear cells of Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Cell Survival; Comet Assay; DNA Damage; Drug Evaluation, Preclinical; Female; Humans; Hydrogen Sulfide; In Vitro Techniques; Leukocytes, Mononuclear; Male; Tetrazolium Salts; Thiazoles; Water | 2015 |
Genotoxic potential of selected cytostatic drugs in human and zebrafish cells.
Topics: Acridine Orange; Animals; Cell Line; Cell Survival; Cisplatin; Cytostatic Agents; Ethidium; Etoposide; Fluorouracil; Hep G2 Cells; Humans; Lymphocytes; Tetrazolium Salts; Thiazoles; Zebrafish | 2016 |
Interference of Phenylethanoid Glycosides from Cistanche tubulosa with the MTT Assay.
Topics: Cell Line; Cell Survival; Cistanche; Glycosides; Humans; Tetrazolium Salts; Thiazoles | 2015 |
In vivo Tracking of Dendritic Cell using MRI Reporter Gene, Ferritin.
Topics: Analysis of Variance; Animals; Blotting, Western; Cell Proliferation; Dendritic Cells; Ferritins; Ferrocyanides; Flow Cytometry; Genes, Reporter; Green Fluorescent Proteins; Humans; Immunotherapy; Interleukin-2 Receptor alpha Subunit; Lentivirus; Lymph Nodes; Magnetic Resonance Imaging; Mice; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2015 |
Synergistic antitumor activity of vitamin D3 combined with metformin in human breast carcinoma MDA-MB-231 cells involves m-TOR related signaling pathways.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Synergism; Female; Humans; Hypoglycemic Agents; Metformin; Signal Transduction; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Vitamins | 2015 |
Vitamin D3 enhances antitumor activity of metformin in human bladder carcinoma SW-780 cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Synergism; Female; Humans; Hypoglycemic Agents; Metformin; Signal Transduction; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms; Vitamins | 2015 |
XPD Functions as a Tumor Suppressor and Dysregulates Autophagy in Cultured HepG2 Cells.
Topics: Annexin A5; Apoptosis; Autophagy; Blotting, Western; Cell Proliferation; Colony-Forming Units Assay; Hep G2 Cells; Humans; In Vitro Techniques; Tetrazolium Salts; Thiazoles; Tumor Suppressor Proteins; Xeroderma Pigmentosum Group D Protein | 2015 |
A new cyclic bisdesmoside from Actinostemma lobatum Maxim.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cisplatin; Coloring Agents; Cucurbitaceae; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Saponins; Tetrazolium Salts; Thiazoles; Triterpenes | 2015 |
Synthesis, crystal structure and biological activity of two Mn complexes with 4-acyl pyrazolone derivatives.
Topics: Animals; Antineoplastic Agents; Cattle; Coordination Complexes; DNA; HeLa Cells; Humans; Intercalating Agents; Ligands; Manganese; Pyrazoles; S Phase Cell Cycle Checkpoints; Schiff Bases; Serum Albumin, Bovine; Spectrometry, Fluorescence; Tetrazolium Salts; Thiazoles | 2015 |
Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autophagy; Cell Line; DNA-Binding Proteins; Endoplasmic Reticulum Stress; Flow Cytometry; Immunoblotting; Mice; Neurons; Peptide Fragments; Tetrazolium Salts; Thiazoles; Valproic Acid | 2015 |
Trans-Resveratrol Induces Apoptosis through ROS-Triggered Mitochondria-Dependent Pathways in A549 Human Lung Adenocarcinoma Epithelial Cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Survival; Epithelial Cells; Fluoresceins; Humans; Lung Neoplasms; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2015 |
Insulin Effects on Survival of Human Multiple Myeloma Cells.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Survival; DNA Primers; Electrophoresis, Agar Gel; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Insulin; Intercellular Signaling Peptides and Proteins; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2015 |
Comparative Metabolomic Profiling of Hepatocellular Carcinoma Cells Treated with Sorafenib Monotherapy vs. Sorafenib-Everolimus Combination Therapy.
Topics: Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Synergism; Everolimus; Fluorescein-5-isothiocyanate; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolomics; Multivariate Analysis; Niacinamide; Phenylurea Compounds; Sorafenib; Tetrazolium Salts; Thiazoles | 2015 |
Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Antineoplastic Agents; Basidiomycota; Drug Screening Assays, Antitumor; Female; Humans; Isoenzymes; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2016 |
MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition.
Topics: alpha Catenin; Animals; Antigens, CD; Blotting, Western; Cadherins; Cell Adhesion; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Luciferases; Lung Neoplasms; Mice; Mice, Inbred BALB C; MicroRNAs; Oligonucleotide Array Sequence Analysis; RNA Interference; Snail Family Transcription Factors; Tetrazolium Salts; Thiazoles; Transcription Factors; Tumor Stem Cell Assay; Vimentin; Zonula Occludens-1 Protein | 2015 |
Therapeutic Potential of Umbilical Cord Mesenchymal Stem Cells for Inhibiting Myofibroblastic Differentiation of Irradiated Human Lung Fibroblasts.
Topics: Analysis of Variance; Blotting, Western; Cell Culture Techniques; Cell Differentiation; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunophenotyping; Lung; Mesenchymal Stem Cells; Radiation Injuries; Tetrazolium Salts; Thiazoles; Umbilical Cord | 2015 |
Oleanolic acid induces mitochondrial-dependent apoptosis and G0/G1 phase arrest in gallbladder cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; G1 Phase; Gallbladder Neoplasms; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Oleanolic Acid; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2015 |
Synthesis of Carbohydrate Capped Silicon Nanoparticles and their Reduced Cytotoxicity, In Vivo Toxicity, and Cellular Uptake.
Topics: Carbohydrates; Cell Line, Tumor; Cell Proliferation; Humans; MCF-7 Cells; Nanoparticles; Particle Size; Silicon; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2015 |
On the photocatalytic reduction of MTT tetrazolium salt on the surface of TiO2 nanoparticles: Formazan production kinetics and mechanism.
Topics: Catalysis; Formazans; Kinetics; Molecular Structure; Nanoparticles; Oxidation-Reduction; Particle Size; Photochemical Processes; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2015 |
Cytotoxicity of Fast-set Conventional and Resin-modified Glass Ionomer Cement Polymerized at Different Times on SHED.
Topics: Cell Culture Techniques; Cell Survival; Coloring Agents; Glass Ionomer Cements; Humans; Materials Testing; Polymerization; Resin Cements; Resins, Synthetic; Stem Cells; Tetrazolium Salts; Thiazoles; Time Factors; Tooth, Deciduous | 2015 |
Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies.
Topics: Acetamides; Animals; Anti-Infective Agents; Bacteria; Biological Availability; Drug Design; Ether-A-Go-Go Potassium Channels; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Models, Molecular; Oxazoles; Oxazolidinones; Potassium Channel Blockers; Staphylococcal Infections; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2015 |
Geleganidines A-C, Unusual Monoterpenoid Indole Alkaloids from Gelsemium elegans.
Topics: Animals; Crystallography, X-Ray; Drugs, Chinese Herbal; Gelsemium; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; PC12 Cells; Plant Roots; Rats; Secologanin Tryptamine Alkaloids; Tetrazolium Salts; Thiazoles | 2015 |
2-Arylquinazolin-4(3H)-ones: Inhibitory Activities Against Xanthine Oxidase.
Topics: 3T3 Cells; alpha-Glucosidases; Animals; Enzyme Assays; Free Radical Scavengers; Glucuronidase; Glycoside Hydrolase Inhibitors; Iron Chelating Agents; Kinetics; Mice; Quinazolinones; Tetrazolium Salts; Thiazoles; Xanthine Oxidase | 2016 |
Cytotoxicity assays as tools to assess water quality in the Sinos River basin.
Topics: Brazil; Cell Culture Techniques; Cell Line, Tumor; Environmental Monitoring; Humans; Neutral Red; Rivers; Tetrazolium Salts; Thiazoles; Toxicity Tests; Water Quality | 2015 |
General Cytotoxicity Assessment by Means of the MTT Assay.
Topics: Animals; BALB 3T3 Cells; Cell Culture Techniques; Cell Survival; Colorimetry; Hepatocytes; Mice; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2015 |
Lentivirus-mediated RNA interference of myostatin gene affects MyoD and Myf5 gene expression in duck embryonic myoblasts.
Topics: Animals; Avian Proteins; Cell Proliferation; Ducks; Embryo, Nonmammalian; Gene Expression Regulation; Genetic Vectors; Lentivirus; Myoblasts; MyoD Protein; Myogenic Regulatory Factor 5; Myostatin; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2015 |
Shotgun proteomic analysis of tiger milk mushroom (Lignosus rhinocerotis) and the isolation of a cytotoxic fungal serine protease from its sclerotium.
Topics: Agaricales; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Databases, Genetic; Drug Screening Assays, Antitumor; Humans; Immunologic Factors; Lectins; Medicine, East Asian Traditional; Proteomics; Serine Proteases; Tetrazolium Salts; Thiazoles | 2015 |
Modulation of quorum sensing-controlled virulence factors by Nymphaea tetragona (water lily) extract.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biofilms; Cell Survival; Chromobacterium; Dose-Response Relationship, Drug; Mice; Microbial Sensitivity Tests; Nymphaea; Plant Extracts; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Rats; Staphylococcus aureus; Tetrazolium Salts; Thiazoles; Virulence Factors | 2015 |
Evidence of ATP assay as an appropriate alternative of MTT assay for cytotoxicity of secondary effluents from WWTPs.
Topics: Adenosine Triphosphate; Apoptosis; Biological Assay; Cell Cycle; Cell Proliferation; Cell Survival; Flow Cytometry; Hep G2 Cells; Humans; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Wastewater; Water Pollutants, Chemical; Water Purification | 2015 |
Antioxidant and anticancer effection of the volatile oil from various habitats of Selaginella doederleinii Hieron.
Topics: Antineoplastic Agents; Antioxidants; Ascorbic Acid; Benzothiazoles; Biphenyl Compounds; Butylated Hydroxytoluene; Cell Line, Tumor; Cell Proliferation; Cisplatin; Ecosystem; Humans; Oils, Volatile; Picrates; Selaginellaceae; Sulfonic Acids; Tetrazolium Salts; Thiazoles | 2015 |
Expression of functional recombinant human fibroblast growth factor 8b and its protective effects on MPP⁺-lesioned PC12 cells.
Topics: Animals; Apoptosis; Baculoviridae; Cell Proliferation; Cell Survival; Chromatography, Affinity; Endoplasmic Reticulum Stress; Fibroblast Growth Factor 8; Humans; Mice; Neuroprotective Agents; NIH 3T3 Cells; Parkinson Disease; PC12 Cells; Rats; Recombinant Proteins; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2016 |
Determination of cytotoxicity of traditional Chinese medicine herbs, Rhizoma coptidis, Radix scutellariae, and Cortex phellodendri, by three methods.
Topics: Annexin A5; Cell Line; Cell Survival; Coloring Agents; Coptis; Drugs, Chinese Herbal; Epithelium, Corneal; Flow Cytometry; Humans; Medicine, Chinese Traditional; Phellodendron; Plant Extracts; Scutellaria baicalensis; Staining and Labeling; Tetrazolium Salts; Thiazoles; Toxicity Tests; Trypan Blue | 2016 |
HMGB-1 as a Potential Target for the Treatment of Diabetic Retinopathy.
Topics: Blood Glucose; Cell Line; Cell Survival; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Humans; Inflammation; NF-kappa B p50 Subunit; Peripheral Nervous System Diseases; Real-Time Polymerase Chain Reaction; Retinal Ganglion Cells; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4; Transfection; Up-Regulation | 2015 |
[Bufalin reverses hepatocyte growth factor-induced resistance to afatinib in H1975 lung cancer cells].
Topics: Afatinib; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bufanolides; Cadherins; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Hepatocyte Growth Factor; Humans; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Quinazolines; Signal Transduction; Tetrazolium Salts; Thiazoles | 2015 |
Comparing Viability of Periodontal Ligament Stem Cells Isolated From Erupted and Impacted Tooth Root.
Topics: Adolescent; Adult; Bicuspid; Cell Culture Techniques; Cell Differentiation; Cell Shape; Cell Survival; Colorimetry; Coloring Agents; Fibroblasts; Humans; Mesenchymal Stem Cells; Molar, Third; Osteogenesis; Periodontal Ligament; Stem Cells; Tetrazolium Salts; Thiazoles; Tooth Eruption; Tooth Root; Tooth, Impacted; Young Adult | 2015 |
Anti-PRRSV effect and mechanism of tetrahydroaltersolanol C in vitro.
Topics: Animals; Anthraquinones; Antiviral Agents; Cell Line; Molecular Structure; Polymerase Chain Reaction; Porcine respiratory and reproductive syndrome virus; Swine; Tetrazolium Salts; Thiazoles; Virus Replication | 2016 |
Cytotoxicity evaluation of large cyanobacterial strain set using selected human and murine in vitro cell models.
Topics: Animals; BALB 3T3 Cells; Cell Line; Complex Mixtures; Cyanobacteria; Cytotoxins; Fibroblasts; HeLa Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Mice; Tetrazolium Salts; Thiazoles | 2016 |
Effect of Ocimum sanctum on Oral Cancer Cell Line: An in vitro Study.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatin; Coloring Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Mouth Neoplasms; Ocimum sanctum; Phytotherapy; Plant Extracts; Plant Leaves; Tetrazolium Salts; Thiazoles | 2015 |
[Indirubin inhibits the proliferation of prostate cancer PC-3 cells].
Topics: Antibiotics, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Cyclin D1; Dose-Response Relationship, Drug; Genes, myc; Humans; Indoles; Male; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Tetrazolium Salts; Thiazoles | 2015 |
Therapeutic targeting of BET protein BRD4 delays murine lupus.
Topics: Animals; Azepines; Disease Progression; DNA; Humans; Kidney; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; Monocytes; Nerve Tissue Proteins; Nuclear Proteins; Proteinuria; Receptors, Cell Surface; Spleen; Tetrazolium Salts; Thiazoles; Transcription Factors; Triazoles | 2015 |
Protective effects of melatonin on lipopolysaccharide-induced mastitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Female; Lipopolysaccharides; Mammary Glands, Animal; Mastitis; Melatonin; Mice; NF-kappa B; Peroxidase; PPAR gamma; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4 | 2015 |
Effects of Hypericum perforatum extract and its main bioactive compounds on the cytotoxicity and expression of CYP1A2 and CYP2D6 in hepatic cells.
Topics: Anthracenes; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Hypericum; Perylene; Phloroglucinol; Plant Extracts; RNA, Neoplasm; Terpenes; Tetrazolium Salts; Thiazoles | 2016 |
Effects of kinase insert domain receptor (KDR) gene silencing on the sensitivity of A549 cells to erlotinib.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Cell Proliferation; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Gene Silencing; Humans; Lung Neoplasms; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Phospholipid Scramblase 1 Interacts with Midkine and Regulates Hepatic Cancer Cell Proliferation and Migration.
Topics: Cell Movement; Cell Nucleolus; Cell Nucleus; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Microscopy, Fluorescence; Midkine; Neoplasm Metastasis; Nerve Growth Factors; Phospholipid Transfer Proteins; Tetrazolium Salts; Thiazoles; Two-Hybrid System Techniques; Wound Healing | 2015 |
Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes.
Topics: Animal Testing Alternatives; Cell Line; Cell Survival; Dermatitis, Allergic Contact; Humans; Interleukin-1alpha; Interleukin-6; Irritants; Keratinocytes; Local Lymph Node Assay; Skin; Tetrazolium Salts; Thiazoles; Xenobiotics | 2016 |
[Effect of estrogen or progesterone combined with paclitaxel on human ovarian cancer cell growth and Drosha expression].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Coloring Agents; Drug Therapy, Combination; Estrogens; Female; Humans; In Vitro Techniques; Ovarian Neoplasms; Paclitaxel; Progesterone; Receptors, Estrogen; Ribonuclease III; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation | 2015 |
Cytotoxicity of Thirdhand Smoke and Identification of Acrolein as a Volatile Thirdhand Smoke Chemical That Inhibits Cell Proliferation.
Topics: A549 Cells; Acrolein; Animals; Cell Cycle; Cell Proliferation; Cell Survival; Fibroblasts; Humans; Mice; Neural Stem Cells; Tetrazolium Salts; Thiazoles; Tobacco Smoke Pollution; Volatile Organic Compounds | 2016 |
Repeated exposure to whole cigarette smoke promotes primary human gingival epithelial cell growth and modulates keratin expression.
Topics: Adolescent; Adult; Apoptosis; bcl-2-Associated X Protein; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Epithelial Cells; Epithelium; Gene Expression Regulation; Gingiva; Humans; Keratins; Nicotiana; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Smoke; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2016 |
[Effect of zoledronic acid on cell proliferation and apoptosis of human periodontal fibroblasts].
Topics: Apoptosis; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Proliferation; Coloring Agents; Diphosphonates; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Gingiva; Humans; Imidazoles; Tetrazolium Salts; Thiazoles; Time Factors; Zoledronic Acid | 2015 |
The hypoxia-mimetic agent CoCl₂ induces chemotherapy resistance in LOVO colorectal cancer cells.
Topics: bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cobalt; Colorectal Neoplasms; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2016 |
NPs/NPRs Signaling Pathways May Be Involved in Depression-Induced Loss of Gastric ICC by Decreasing the Production of mSCF.
Topics: Animals; Body Weight; Cell Proliferation; Depression; Down-Regulation; Gastric Mucosa; Gene Expression Regulation; Interstitial Cells of Cajal; Male; Myocytes, Smooth Muscle; Natriuretic Peptides; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Signal Transduction; Stem Cell Factor; Tetrazolium Salts; Thiazoles; Up-Regulation | 2016 |
Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay.
Topics: Biological Assay; Cell Survival; Chromatography, High Pressure Liquid; Cosmetics; Epidermis; Humans; In Vitro Techniques; Oxidation-Reduction; Skin Irritancy Tests; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2016 |
Determination of Cytotoxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bioprospecting; Cell Survival; Colorimetry; Coloring Agents; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microscopy; Neoplasms; Phytochemicals; Phytotherapy; Plant Extracts; Plants, Medicinal; Tetrazolium Salts; Thiazoles; Trypan Blue | 2016 |
In vitro evaluation of inorganic and methyl mercury mediated cytotoxic effect on neural cells derived from different animal species.
Topics: Animals; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Mercuric Chloride; Methylmercury Compounds; Mice; Neurons; Neutral Red; Rosaniline Dyes; Tetrazolium Salts; Thiazoles; Turtles | 2016 |
Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Drug Synergism; Formazans; Gas Chromatography-Mass Spectrometry; Imipramine; Leishmania mexicana; Macrophages, Peritoneal; Mice; Miconazole; Parasitic Sensitivity Tests; Sterols; Tetrazolium Salts; Thiazoles | 2016 |
Anti-Inflammatory Effect of Dexamethasone Controlled Released From Anterior Suprachoroidal Polyurethane Implants on Endotoxin-Induced Uveitis in Rats.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Ciliary Body; Coloring Agents; Cytokines; Dexamethasone; Disease Models, Animal; Drug Delivery Systems; Drug Implants; Extracellular Space; Female; Humans; Iris; Lipopolysaccharides; Polyurethanes; Rats; Rats, Inbred Lew; Retinal Pigment Epithelium; Salmonella typhimurium; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Uveitis | 2016 |
In Vitro and In Vivo Toxicity Evaluation of Colloidal Silver Nanoparticles Used in Endodontic Treatments.
Topics: Ammonia; Animals; Cell Line; Cell Survival; Connective Tissue; Dental Materials; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibrin; Fibroblasts; Inflammation; Interleukin-1beta; Interleukin-6; Male; Materials Testing; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Neutrophils; Particle Size; Porifera; Povidone; Rats; Rats, Wistar; Silver; Stem Cell Factor; Subcutaneous Tissue; Tetrazolium Salts; Thiazoles; Time Factors; Toxicity Tests | 2016 |
The Comparison of MTT and CVS Assays for the Assessment of Anticancer Agent Interactions.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Drug Interactions; Drug Screening Assays, Antitumor; Drug Synergism; Gentian Violet; HT29 Cells; Humans; Inhibitory Concentration 50; Isothiocyanates; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondria; Reactive Oxygen Species; Reproducibility of Results; Selenium Compounds; Software; Tetrazolium Salts; Thiazoles | 2016 |
The MTT and Crystal Violet Assays: Potential Confounders in Nanoparticle Toxicity Testing.
Topics: Biological Assay; Cadmium Compounds; Cell Line; Gentian Violet; Gold; Humans; Nanoparticles; Organosilicon Compounds; Silicon Dioxide; Soot; Sulfides; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2016 |
Possible neuroprotective mechanisms of clove oil against icv-colchicine induced cognitive dysfunction.
Topics: Acetylcholinesterase; Animals; Brain; Clove Oil; Cognition Disorders; Colchicine; Drug Synergism; Electron Transport Complex IV; Infusions, Intraventricular; Male; Minocycline; Mitochondria; NADH Dehydrogenase; Neuroprotective Agents; Oxidative Stress; Rats; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles | 2016 |
Curcumin hampers the antitumor effect of vinblastine via the inhibition of microtubule dynamics and mitochondrial membrane potential in HeLa cervical cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Survival; Curcumin; Drug Synergism; Female; HeLa Cells; Humans; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Microtubules; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Vinblastine | 2016 |
Effects of Er,Cr:YSGG Laser Treatment on Human Gingival Fibroblast Attachment, Viability and Morphology of Root Surface: An In Vitro Study.
Topics: Apoptosis; Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Coloring Agents; Curettage; Dental Scaling; Fibroblasts; Gingiva; Humans; Lasers, Solid-State; Microscopy, Electron, Scanning; Piezosurgery; Tetrazolium Salts; Thiazoles; Tooth Root | 2016 |
Inhibitory effects of bevacizumab monoclonal antibodies in combination with chemotherapy in different time sequences on a human gastric carcinoma cell line.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevacizumab; Cell Cycle; Cell Line, Tumor; Fluorouracil; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2017 |
The cytotoxicity study of praziquantel enantiomers.
Topics: Cell Line, Tumor; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Praziquantel; Schistosomiasis; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2016 |
In vitro evaluation of osteoblast responses to carbon nanotube-coated titanium surfaces.
Topics: Alkaline Phosphatase; Animals; Anthraquinones; Calcification, Physiologic; Cell Differentiation; Cell Line; Cell Proliferation; Cells, Cultured; Collagen; Materials Testing; Mice; Microscopy, Electron, Scanning; Nanotubes, Carbon; Osteoblasts; Surface Properties; Tetrazolium Salts; Thiazoles; Titanium | 2016 |
Troglitazone Enhances the Apoptotic Response of DLD-1 Colon Cancer Cells to Photodynamic Therapy.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Photochemotherapy; PPAR gamma; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Troglitazone | 2016 |
Apple ethanol extract promotes proliferation of human adult stem cells, which involves the regenerative potential of stem cells.
Topics: Adipose Tissue; Adult; Adult Stem Cells; Cell Differentiation; Cell Proliferation; Deoxyuridine; Eukaryotic Initiation Factors; Fetal Blood; Humans; Interleukin-6; Malus; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plant Extracts; Regeneration; Ribosomal Protein S6 Kinases, 70-kDa; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2016 |
Chemical constituents and antitumor activity from Paris polyphylla Smith var. yunnanensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Gas Chromatography-Mass Spectrometry; Liliaceae; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Molecular Conformation; Rhizome; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2017 |
Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Diosgenin; DNA Fragmentation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2016 |
Cytotoxicity of Odorous Compounds from Poultry Manure.
Topics: Air Pollutants; Animals; Cell Line, Tumor; Chickens; Inhibitory Concentration 50; Manure; Odorants; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2016 |
Palmitic acid triggers cell apoptosis in RGC-5 retinal ganglion cells through the Akt/FoxO1 signaling pathway.
Topics: Animals; Apoptosis; Cell Line; Gene Knockdown Techniques; Malondialdehyde; Nerve Tissue Proteins; Oncogene Protein v-akt; Palmitic Acid; Rats; Reactive Oxygen Species; Retinal Ganglion Cells; RNA, Small Interfering; Signal Transduction; Tetrazolium Salts; Thiazoles | 2017 |
A novel therapy for ovarian cancer using real‑time imaging.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coloring Agents; Doxorubicin; Female; Flow Cytometry; Folic Acid; Humans; Microscopy, Confocal; Optical Imaging; Ovarian Neoplasms; Ovary; Prodrugs; Tetrazolium Salts; Thiazoles | 2017 |
Preparation and characterization of a silk fibroin/calcium sulfate bone cement.
Topics: Animals; Bone Cements; Calcium Sulfate; Cell Proliferation; Compressive Strength; Fibroins; Materials Testing; Mesenchymal Stem Cells; Rats; Silk; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2018 |
Magnolol and honokiol from Magnolia officinalis enhanced antiviral immune responses against grass carp reovirus in Ctenopharyngodon idella kidney cells.
Topics: Animals; Biphenyl Compounds; Carps; Cell Line; Colorimetry; Cytopathogenic Effect, Viral; Fish Diseases; Immunity, Innate; Lignans; Magnolia; Reoviridae; Reoviridae Infections; Tetrazolium Salts; Thiazoles | 2017 |
Substrate-Specific Reduction of Tetrazolium Salts by Isolated Mitochondria, Tissues, and Leukocytes.
Topics: Animals; Humans; Leukocytes; Male; Mitochondria, Liver; Nitroblue Tetrazolium; Oxidation-Reduction; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2017 |
Immune responses to highly conserved influenza A virus matrix 1 peptides.
Topics: Cell Proliferation; Cross Reactions; Epitopes, T-Lymphocyte; Healthy Volunteers; Humans; Immunogenicity, Vaccine; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Interferon-gamma; Leukocytes, Mononuclear; Lymphocytes; Tetrazolium Salts; Thiazoles; Viral Matrix Proteins; Viral Proteins | 2017 |
A novel epidermal growth factor receptor inhibitor for treating lung cancer.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Proliferation; ErbB Receptors; Humans; Lung Neoplasms; Phenyl Ethers; Piperazines; Protein Kinase Inhibitors; Signal Transduction; Tetrazolium Salts; Thiazoles | 2017 |
Design and Synthesis of New Anticancer Glycyrrhetinic Acids and Oleanolic Acids.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Glycyrrhetinic Acid; Hep G2 Cells; Humans; MCF-7 Cells; Oleanolic Acid; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2017 |
Basic Colorimetric Proliferation Assays: MTT, WST, and Resazurin.
Topics: Biological Assay; Calibration; Cell Count; Cell Proliferation; Cell Survival; Colorimetry; HeLa Cells; Humans; Indicators and Reagents; NAD; NADP; Oxazines; Tetrazolium Salts; Thiazoles; Xanthenes | 2017 |
Airborne particulate matter (PM2.5) triggers autophagy in human corneal epithelial cell line.
Topics: Air Pollutants; Apoptosis; Autophagy; Cell Line; Cell Proliferation; Cell Survival; Deoxyuridine; Epithelial Cells; Humans; Particulate Matter; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2017 |
Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caco-2 Cells; Caspase 3; Caspase 8; Caspase 9; Cell Proliferation; Colorectal Neoplasms; Fluorouracil; HT29 Cells; Humans; Indoles; Pichia; Probiotics; Tetrazoles; Tetrazolium Salts; Thiazoles | 2017 |
MicroRNA-200c represses migration and invasion of gastric cancer SGC-7901 cells by inhibiting expression of fibronectin 1.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Cytokines; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2017 |
[Cancer-associated-fibroblasts regulate the chemoresistance of lung cancer cell line A549 via SDF-1 secretion].
Topics: A549 Cells; Apoptosis; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Chemokine CXCL12; Coloring Agents; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Lung Neoplasms; Receptors, CXCR4; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Microenvironment | 2017 |
Development of a novel bioactive glass suitable for osteosarcoma-related bone grafts.
Topics: Bone Neoplasms; Bone Substitutes; Borates; Cell Line, Tumor; Cell Proliferation; Gallium; Glass; Humans; Osteoblasts; Osteosarcoma; Powders; Tetrazolium Salts; Thiazoles; Zinc Compounds | 2018 |
Enhanced antitumor activity in A431 cells via encapsulation of 20(R)-ginsenoside Rg3 in PLGA nanoparticles.
Topics: Antineoplastic Agents; Cell Proliferation; Ginsenosides; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles | 2017 |
Effects of drinking desalinated seawater on cell viability and proliferation.
Topics: Animals; Annexin A5; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Drinking Water; Fluorescein-5-isothiocyanate; Mice; Minerals; NIH 3T3 Cells; Propidium; Seawater; Staining and Labeling; Tetrazolium Salts; Thiazoles; Water Purification | 2017 |
Disruption of Functional Activity of Mitochondria during MTT Assay of Viability of Cultured Neurons.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Electron Transport Complex I; Electron Transport Complex III; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Neurites; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2017 |
Heme oxygenase-1 derived carbon monoxide suppresses Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Antioxidants; Astrocytes; Carbon Monoxide; Heme Oxygenase (Decyclizing); Homeostasis; Neurons; Nitric Oxide; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2017 |
Functional characterization of a soluble NADPH-cytochrome P450 reductase from Fusarium graminearum.
Topics: Cloning, Molecular; Cytochromes c; Enzyme Assays; Escherichia coli; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Fungal Proteins; Fusarium; Gene Expression; Genetic Vectors; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; NADPH-Ferrihemoprotein Reductase; Oligopeptides; Oxidation-Reduction; Recombinant Fusion Proteins; Substrate Specificity; Temperature; Tetrazolium Salts; Thiazoles; Trichothecenes | 2017 |
Polyphenolic contents, antioxidant activities and UPLC-ESI-MS analysis of Haplophyllum tuberculatum A. Juss leaves extracts.
Topics: Alkaloids; Antioxidants; beta Carotene; Chromatography, Liquid; Flavonoids; Plant Extracts; Plant Leaves; Polyphenols; Rutaceae; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2018 |
Screening for the presence of lipophilic marine biotoxins in shellfish samples using the neuro-2a bioassay.
Topics: Animals; Biological Assay; Marine Toxins; Mice; Shellfish; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2018 |
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
Topics: Anti-Inflammatory Agents; Antioxidants; Coumarins; Cyclooxygenase Inhibitors; Lipid Peroxidation; Molecular Structure; Plant Extracts; Tetrazoles; Tetrazolium Salts; Thiazoles | 2017 |
Synthesis and evaluation of coumarin derivatives against human lung cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Coumarins; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Reference Values; Reproducibility of Results; Tetrazolium Salts; Thiazoles | 2017 |
Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial Cells; Gene Expression Profiling; Glycoproteins; Humans; Newcastle disease virus; Peptide Fragments; Staining and Labeling; Tetrazolium Salts; Thiazoles; Viral Proteins | 2017 |
Production and mechanical properties of Ti-5Al-2.5Fe-xCu alloys for biomedical applications.
Topics: Alloys; Anti-Bacterial Agents; Biocompatible Materials; Compressive Strength; Copper; Corrosion; Escherichia coli; Hardness; HeLa Cells; Hot Temperature; Humans; Materials Testing; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Particle Size; Powders; Staphylococcus aureus; Stress, Mechanical; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2018 |
Esculetin Attenuates the Growth of Lung Cancer by Downregulating Wnt Targeted Genes and Suppressing NF-κB.
Topics: Animals; Apoptosis; beta Catenin; Carcinoma, Lewis Lung; Cell Proliferation; Coloring Agents; Cyclin D1; Down-Regulation; Female; Heterografts; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; NF-kappa B; Salivary alpha-Amylases; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Umbelliferones; Wnt Proteins | 2018 |
Effects of atmospheric non-thermal argon/oxygen plasma on biofilm viability and hydrophobicity of oral bacteria.
Topics: Argon; Atmospheric Pressure; Biofilms; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Microbial Viability; Microbiota; Oxygen; Plasma Gases; Streptococcus mutans; Streptococcus sanguis; Tetrazolium Salts; Thiazoles | 2017 |
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells.
Topics: A549 Cells; Alstonia; Antineoplastic Agents; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Phytosterols; Plant Extracts; Plant Leaves; Sterols; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid | 2017 |
Cell Enumeration Assays: Application of the MTT and Sulforhodamine B Assays to Lipopolysaccharide-Stimulated Neonatal Rodent Microglia.
Topics: Animals; Animals, Newborn; Calorimetry; Cell Count; Cells, Cultured; Lipopolysaccharides; Mice; Microglia; Rats; Rhodamines; Tetrazolium Salts; Thiazoles | 2018 |
Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy.
Topics: Analysis of Variance; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; beta Catenin; Blotting, Western; Cell Migration Assays; Cell Proliferation; Cisplatin; Colonic Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Long Noncoding; Signal Transduction; Tetrazolium Salts; Thiazoles | 2017 |
Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition.
Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Cytological Techniques; Formazans; Humans; Metabolism; Mice; Organelle Biogenesis; Radiation; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2018 |
Novel ethanocycloheptono [3,4,5-kl]benzo[a]xanthene induces apoptosis in BEL-7402 cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Caspase 7; Cell Line, Tumor; Comet Assay; Crystallography, X-Ray; DNA Damage; Down-Regulation; Enzyme Activation; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Molecular Structure; Protein Binding; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; S Phase; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles; Xanthenes | 2018 |
Culture of human dental pulp cells at variable times post-tooth extraction.
Topics: Analysis of Variance; Cell Count; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media; Dental Pulp; Humans; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Preservation; Tooth Extraction | 2018 |
Determination of the Selection Capacity of Antibiotics for Gene Selection.
Topics: Anti-Bacterial Agents; Cell Count; Cell Culture Techniques; Genetic Techniques; Genetic Vectors; HeLa Cells; Humans; Linear Models; Tetrazolium Salts; Thiazoles; Transfection | 2018 |
Synthetic Dibenzoxanthene Derivatives Induce Apoptosis Through Mitochondrial Pathway in Human Hepatocellular Cancer Cells.
Topics: Apoptosis; Blotting, Western; Carbon-13 Magnetic Resonance Spectroscopy; Caspases; Cell Proliferation; Chromatography, Liquid; Comet Assay; DNA Damage; Hep G2 Cells; Humans; Mass Spectrometry; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Proton Magnetic Resonance Spectroscopy; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Xanthenes | 2018 |
Anti-Candida activity of antidepressants sertraline and fluoxetine: effect upon pre-formed biofilms.
Topics: Antidepressive Agents; Antifungal Agents; Biofilms; Candida; Drug Repositioning; Fluoxetine; Formazans; Gentian Violet; Humans; Microbial Sensitivity Tests; Microbial Viability; Sertraline; Staining and Labeling; Tetrazolium Salts; Thiazoles | 2018 |
In vitro cytotoxic evaluation of novel fast-setting calcium silicate cement compositions and dental materials using colorimetric methyl-thiazolyl-tetrazolium assay.
Topics: Animals; Calcium Compounds; Cell Line; Cell Survival; Colorimetry; Dental Cements; In Vitro Techniques; Mice; Silicates; Tetrazolium Salts; Thiazoles | 2018 |
Colorimetric method for determining viability of sea urchin sperm applied in toxicity tests.
Topics: Ammonium Compounds; Animals; Cell Survival; Colorimetry; Formazans; Lytechinus; Male; Metals, Heavy; Sodium Dodecyl Sulfate; Spermatozoa; Tetrazolium Salts; Thiazoles; Toxicity Tests; Water Pollutants, Chemical | 2018 |
Diosgenin induces genotoxic and mutagenic effects on HepG2 cells.
Topics: Cell Survival; Comet Assay; Dioscorea; Diosgenin; Hep G2 Cells; Humans; Micronucleus Tests; Mutagens; Tetrazolium Salts; Thiazoles | 2018 |
Inhibitory effect of selenomethionine on carcinogenesis in the model of human colorectal cancer in vitro and its link to the Wnt/β-catenin pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; beta Catenin; Blotting, Western; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Genes, myc; Glycogen Synthase Kinase 3 beta; HT29 Cells; Humans; Models, Biological; Phosphorylation; Real-Time Polymerase Chain Reaction; RNA, Messenger; Selenomethionine; Tetrazolium Salts; Thiazoles; Wnt Signaling Pathway | 2018 |
Ovicidal in vitro activity of 2-aryl-3-(2-morpholinoethyl)thiazolidin-4-ones and 2-aryl-3-(3-morpholinopropyl)thiazolidin-4-ones against Fasciola hepatica (Linnaeus, 1758).
Topics: Animals; Anthelmintics; Brazil; Cattle; Cell Line; Fasciola hepatica; Inhibitory Concentration 50; Kidney; Liver; Ovum; Parasite Egg Count; Tetrazolium Salts; Thiazoles; Thiazolidines | 2018 |
Enhancing the Cancer Cell Growth Inhibitory Effects of Table Grape Anthocyanins.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caco-2 Cells; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Female; Fruit; Glucosides; HT29 Cells; Humans; Methylation; Nitriles; Oxidative Stress; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles; Vitis | 2018 |
Electrochemical Detection of Viable Bacterial Cells Using a Tetrazolium Salt.
Topics: Bacteria; Bacteriological Techniques; Electrochemical Techniques; Electrodes; Equipment Design; Microbial Viability; Oxidation-Reduction; Solubility; Tetrazolium Salts; Thiazoles | 2018 |
Topics: Acanthaceae; Animals; Anti-Inflammatory Agents; Chromatography, Liquid; Interferon-gamma; Least-Squares Analysis; Lipopolysaccharides; Macrophage Activation; Metabolomics; Mice; Multivariate Analysis; Nitric Oxide; Phenols; Plant Extracts; Plant Leaves; Principal Component Analysis; Proton Magnetic Resonance Spectroscopy; RAW 264.7 Cells; Reference Standards; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles; Water | 2019 |
Comprehensive characterisation of polyphenols in leaves and stems of three anti-dengue virus type-2 active Brazilian Faramea species (Rubiaceae) by HPLC-DAD-ESI-MS/MS.
Topics: Animals; Antiviral Agents; Brazil; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cricetinae; Dengue Virus; Flavonoids; Hep G2 Cells; Humans; Plant Leaves; Plant Stems; Polyphenols; Rubiaceae; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrazolium Salts; Thiazoles | 2019 |
On the prediction of cytotoxicity of diverse chemicals for topminnow (Poeciliopsis lucida) hepatoma cell line, PLHC-1
Topics: Animals; Cell Line, Tumor; Cytotoxins; Fundulidae; Models, Molecular; Phenazines; Quantitative Structure-Activity Relationship; Tetrazoles; Tetrazolium Salts; Thiazoles; Toxicity Tests | 2018 |
Cryotherapy: biochemical alterations involved in reduction of damage induced by exhaustive exercise.
Topics: Acetylcholinesterase; Animals; Antioxidants; Cell Survival; Cold Temperature; Cryotherapy; Fluoresceins; Immersion; Male; Mice; Muscle, Skeletal; Myositis; Physical Conditioning, Animal; Reactive Oxygen Species; Reproducibility of Results; Swimming; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome; Water | 2018 |
Evaluation of Cytotoxic Effect and Antioxidant Activity of Grape Seed Extract, Crocin, and Phenytoin.
Topics: Carotenoids; Free Radical Scavengers; Grape Seed Extract; Humans; MCF-7 Cells; Phenytoin; Tetrazolium Salts; Thiazoles | 2017 |
Phytochemical Content, Antioxidant and Cytotoxic Activities of Sedum spurium.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Cell Survival; Erythrocytes; Free Radicals; Humans; Hydrogen Peroxide; Phytochemicals; Plant Extracts; Plants, Medicinal; Sedum; Tetrazolium Salts; Thiazoles | 2016 |
Investigation of the antimicrobial activity of a short cationic peptide against promastigote and amastigote forms of Leishmania major (MHRO/IR/75/ER): An in vitro study.
Topics: Animals; Antimicrobial Cationic Peptides; Antiprotozoal Agents; Coloring Agents; DNA, Protozoan; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Leishmania major; Leishmaniasis, Cutaneous; Macrophages; Meglumine Antimoniate; Mice; RAW 264.7 Cells; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Trypan Blue | 2019 |
Deferoxamine but Not Dimethyloxalylglycine, L-Mimosine, or Cobalt Dichloride Can Interfere with the MTT Assay.
Topics: 3T3 Cells; Amino Acids, Dicarboxylic; Animals; Biocompatible Materials; Cell Line; Cell Survival; Cobalt; Deferoxamine; Dimethyl Sulfoxide; Mice; Mimosine; Tetrazolium Salts; Thiazoles | 2018 |
Fabrication and Cytocompatibility Evaluation of Psyllium Husk (Isabgol)/Gelatin Composite Scaffolds.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Survival; Gelatin; In Vitro Techniques; Mechanical Phenomena; Mice; Microscopy, Electron, Scanning; Psyllium; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2019 |
Anti-parasitic effect on Toxoplasma gondii induced by a spider peptide lycosin-I.
Topics: Animals; Antimicrobial Cationic Peptides; Cell Count; Cell Membrane; Cells, Cultured; Coccidiostats; Female; Fibroblasts; Humans; Interleukin-6; Interleukin-8; Male; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Real-Time Polymerase Chain Reaction; Spider Venoms; Tetrazolium Salts; Thiazoles; Toxoplasma; Trypan Blue | 2019 |
Inhibition of didscoidin domain receptor 1 reduces epithelial-mesenchymal transition and induce cell-cycle arrest and apoptosis in prostate cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Discoidin Domain Receptor 1; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 2; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 7; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetrazolium Salts; Thiazoles | 2019 |
PELI3 mediates pro-tumor actions of down-regulated miR-365a-5p in non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Coloring Agents; Disease Models, Animal; Down-Regulation; Humans; Lung Neoplasms; MicroRNAs; Tetrazolium Salts; Thiazoles; Ubiquitin-Protein Ligases | 2019 |
Use of a colorimetric assay to evaluate the proliferation of canine mammary tumor cells exposed to propofol.
Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cell Proliferation; Colorimetry; Coloring Agents; Dog Diseases; Dogs; Female; Hypnotics and Sedatives; Mammary Neoplasms, Animal; Propofol; Tetrazolium Salts; Thiazoles | 2019 |
Fucosylated umbilical cord blood hematopoietic stem cell expansion on selectin-coated scaffolds.
Topics: Cell Line; Cell Survival; Fetal Blood; Fucose; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Nanostructures; Selectins; Surface Properties; Tetrazolium Salts; Thiazoles; Tissue Scaffolds | 2019 |
Hormonal modulation of Toxoplasma gondii infection: Regulation of hormonal receptors and cytokine production in THP-1 cells.
Topics: Animals; Coloring Agents; Cytokines; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Mice; Progesterone; Prolactin; Protein Isoforms; Receptors, Prolactin; Tetrazolium Salts; Thiazoles; THP-1 Cells; Toxoplasma | 2019 |
Nesfatin-1 protects PC12 cells against high glucose-induced cytotoxicity via inhibiting oxidative stress, autophagy and apoptosis.
Topics: Animals; Apoptosis; Autophagy; Cell Survival; Diabetic Neuropathies; Glucose; Membrane Potential, Mitochondrial; Necrosis; Neuroprotective Agents; Nucleobindins; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2019 |
A novel thymol-doped enamel bonding system: Physico-mechanical properties, bonding strength, and biological activity.
Topics: Acid Etching, Dental; Anti-Bacterial Agents; Bicuspid; Colorimetry; Composite Resins; Dentin-Bonding Agents; Elasticity; Fibroblasts; Humans; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Resin Cements; Resins, Synthetic; Shear Strength; Spectroscopy, Fourier Transform Infrared; Streptococcus mutans; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles; Thymol; Viscosity | 2019 |
Fabrication and biological activity of polycaprolactone/phlorotannin endotracheal tube to prevent tracheal stenosis: An in vitro and in vivo study.
Topics: Animals; Biocompatible Materials; Cell Line; Fibrosis; Humans; In Vitro Techniques; Intubation, Intratracheal; Male; Materials Testing; Mucous Membrane; Polyesters; Rabbits; Tetrazolium Salts; Thiazoles; Trachea; Tracheal Stenosis; Transforming Growth Factor beta1 | 2020 |
Effect of growth media on the MTT colorimetric assay in bacteria.
Topics: Anaerobiosis; Colorimetry; Culture Media; Escherichia coli; Formazans; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2019 |
Assessment of Sertoli Cell Proliferation by 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide and Sulforhodamine B Assays.
Topics: Animals; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Male; Rhodamines; Sertoli Cells; Tetrazolium Salts; Thiazoles | 2019 |
Designing and optimization of an electrochemical substitute for the MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cell viability assay.
Topics: Biosensing Techniques; Cost-Benefit Analysis; Electrochemistry; Formazans; Hydrogen-Ion Concentration; Oxidation-Reduction; Potentiometry; Reproducibility of Results; Saccharomyces cerevisiae; Sensitivity and Specificity; Solvents; Tetrazolium Salts; Thiazoles | 2019 |
Caveats to the use of MTT, neutral red, Hoechst and Resazurin to measure silver nanoparticle cytotoxicity.
Topics: Animals; Biological Assay; Cell Line; Cell Survival; Coloring Agents; Metal Nanoparticles; Mice; Neutral Red; Oxazines; Particle Size; Povidone; Silver; Surface Properties; Tetrazolium Salts; Thiazoles; Xanthenes | 2020 |
Prdx6 is required to protect human corneal epithelial cells against ultraviolet B injury.
Topics: Animals; Apoptosis; Cell Survival; Coloring Agents; Epithelium, Corneal; Gene Expression Regulation; Humans; Malondialdehyde; Peroxidase; Peroxiredoxin VI; Phospholipases A2; Plasmids; Radiation Injuries, Experimental; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Ultraviolet Rays | 2021 |
Protective effect of cholecystokinin octapeptide on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells.
Topics: Angiotensin II; Animals; Apoptosis; Benzimidazoles; Cell Line; Cell Survival; Cholecystokinin; Gene Expression Profiling; Gene Expression Regulation; Myocardium; Myocytes, Cardiac; Peptides; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2020 |
Evaluation of veterinary autogenous vaccines safety by an MTT in-vitro cytotoxicity assay.
Topics: Animals; Autovaccines; Cell Line; Fibroblasts; Guinea Pigs; In Vitro Techniques; Italy; Mice; Tetrazolium Salts; Thiazoles | 2019 |
Tumor-targeting and redox-sensitive micelles based on hyaluronic acid conjugate for delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disulfides; Drug Delivery Systems; Hemolysis; Humans; Hyaluronic Acid; In Vitro Techniques; MCF-7 Cells; Mice; Micelles; Microscopy, Electron, Transmission; Neoplasms; Oxidation-Reduction; Paclitaxel; Polyethylene Glycols; Polymers; Rabbits; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2020 |
Structural Doubling Time Predicts Overall Survival in Patients with Medullary Thyroid Cancer in Patients with Rapidly Progressive Metastatic Medullary Thyroid Cancer Treated with Molecular Targeted Therapies.
Topics: Adolescent; Adult; Aged; Calcitonin; Carcinoembryonic Antigen; Carcinoma, Neuroendocrine; Cell Proliferation; Disease Progression; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Liver Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Prognosis; Retrospective Studies; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2020 |
3-Hydroxyhexanoate-based polycationic nanoparticle system for delivering reprogramming factors.
Topics: Caproates; Cellular Reprogramming; Gene Expression; Green Fluorescent Proteins; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Nanoparticles; Octamer Transcription Factor-3; Particle Size; Paxillin; SOXB1 Transcription Factors; Tetrazolium Salts; Thiazoles; Transfection | 2020 |
Fabrication and characterization of a novel compliant small-diameter PET/PU/PCL triad-hybrid vascular graft.
Topics: Animals; Biocompatible Materials; Biomechanical Phenomena; Blood Vessel Prosthesis; Calorimetry, Differential Scanning; Cells, Cultured; Chlorocebus aethiops; Extracellular Matrix; Immune System; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polyethylene Terephthalates; Polyurethanes; Porosity; Pressure; Rats; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Vero Cells | 2020 |
Monomeric C-reactive protein affects cell injury and apoptosis through activation of p38 mitogen-activated protein kinase in human coronary artery endothelial cells.
Topics: Antigens, CD; Apoptosis; Atherosclerosis; C-Reactive Protein; Cell Adhesion; Cell Adhesion Molecules; Cell Proliferation; Cells, Cultured; Coronary Vessels; Cyclooxygenase 2; Endothelial Cells; Humans; Imidazoles; Inflammation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors; Vascular Endothelial Growth Factor A | 2020 |
Synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as possible anticancer agents.
Topics: A549 Cells; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Survival; Cisplatin; Drug Design; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mice; NIH 3T3 Cells; Structure-Activity Relationship; Tetrazolium Salts; Thiadiazoles; Thiazoles | 2020 |
Development of osteogenic chitosan/alginate scaffolds reinforced with silicocarnotite containing apatitic fibers.
Topics: Alginates; Apatites; Biocompatible Materials; Calcium Phosphates; Cell Line, Tumor; Cell Proliferation; Chitosan; Compressive Strength; Humans; Materials Testing; Microscopy, Electron, Scanning; Osteogenesis; Polymers; Porosity; Regeneration; Silicates; Spectroscopy, Fourier Transform Infrared; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; X-Ray Diffraction | 2020 |
Zirconia-containing wollastonite ceramics derived from biowaste resources for bone tissue engineering.
Topics: Biocompatible Materials; Buffers; Calcium Compounds; Cell Line, Tumor; Cell Survival; Ceramics; Durapatite; Humans; In Vitro Techniques; Materials Testing; Microscopy, Electron, Scanning; Osteosarcoma; Silicates; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thermogravimetry; Thiazoles; Tissue Engineering; X-Ray Diffraction; Zirconium | 2020 |
Oxidovanadium(IV) Complex Disrupts Mitochondrial Membrane Potential and Induces Apoptosis in Pancreatic Cancer Cells.
Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Ligands; Membrane Potential, Mitochondrial; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vanadium | 2021 |
Precise engineering of neutrophil membrane coated with polymeric nanoparticles concurrently absorbing of proinflammatory cytokines and endotoxins for management of sepsis.
Topics: Animals; Biomimetics; CD40 Antigens; Cell Membrane; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cytokines; Endotoxins; Female; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Nanoparticles; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Polymers; Sepsis; Spleen; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2020 |
Development of fibrous PLGA/fibrin scaffolds as a potential skin substitute.
Topics: Animals; Cell Adhesion; Cell Survival; Cells, Cultured; Fibrin; Formates; Lactic Acid; Male; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Skin, Artificial; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2020 |
Modulatory Activities of Plant Extracts on Jellyfish Cytotoxicity.
Topics: Ananas; Animals; Antivenins; Carica; Cnidarian Venoms; Mice; Plant Extracts; Rubiaceae; Scyphozoa; Tetrazolium Salts; Thiazoles | 2020 |
Basic information for the development of a toxicity assay in inactivated bacterial vaccines.
Topics: Animals; Bacterial Vaccines; In Vitro Techniques; Macrophages; Sus scrofa; Tetrazolium Salts; Thiazoles; Toxicity Tests; Vaccines, Inactivated | 2020 |
Anti-Inflammatory and Antioxidant Effects of
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asteraceae; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Proteins; Methanol; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; RAW 264.7 Cells; Reactive Oxygen Species; Sepsis; Tetrazolium Salts; Thiazoles | 2020 |
High-Throughput Rapid Yeast Chronological Lifespan Assay.
Topics: Biological Assay; Cellular Senescence; Data Analysis; High-Throughput Screening Assays; Longevity; Saccharomyces cerevisiae; Tetrazolium Salts; Thiazoles; Yeasts | 2021 |
Cisplatin-loaded albumin nanoparticle and study their internalization effect by using β-cyclodextrin.
Topics: Albumins; Animals; Antineoplastic Agents; beta-Cyclodextrins; Cattle; Cell Death; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Delivery Systems; Endocytosis; Flow Cytometry; Humans; MCF-7 Cells; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanomedicine; Nanoparticles; Particle Size; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2021 |
Comparison of antifungal and cytotoxicity activities of titanium dioxide and zinc oxide nanoparticles with amphotericin B against different Candida species: In vitro evaluation.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida; Cell Line; Cell Survival; Metal Nanoparticles; Mice; Microbial Sensitivity Tests; Tetrazolium Salts; Thiazoles; Titanium; Zinc Oxide | 2021 |
Fabrication, optimisation and
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cobalt; Curcumin; Docetaxel; Drug Delivery Systems; Drug Screening Assays, Antitumor; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lipids; Lung Neoplasms; Microspheres; Nanostructures; Particle Size; Temperature; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2020 |
Evaluation of a novel biodegradable ureteral stent produced from polyurethane and magnesium alloys.
Topics: Alloys; Animals; Biocompatible Materials; Cell Survival; Female; Magnesium; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Polyurethanes; Pressure; Rabbits; Stents; Swine; Tetrazolium Salts; Thiazoles; Ureter | 2021 |
Exploring the Therapeutic Efficacy of Zingerone Nanoparticles in Treating Biofilm-Associated Pyelonephritis Caused by Pseudomonas aeruginosa in the Murine Model.
Topics: Animals; Biofilms; Disease Models, Animal; Guaiacol; HEK293 Cells; Humans; Inflammation; Malondialdehyde; Mice; Microscopy, Electron, Scanning; Nanoparticles; Peroxidase; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Pyelonephritis; Stem Cells; Tetrazolium Salts; Thiazoles | 2020 |
Chemical Composition, Antioxidant and Cytotoxic Activities of
Topics: Antioxidants; Burkina Faso; Cations; Cell Line, Tumor; Female; Flow Cytometry; Free Radicals; Gas Chromatography-Mass Spectrometry; HeLa Cells; Humans; Hyptis; In Vitro Techniques; Inhibitory Concentration 50; Male; Monoterpenes; Oils, Volatile; Plant Extracts; Prostatic Neoplasms; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2020 |
DRAQ7 as an Alternative to MTT Assay for Measuring Viability of Glioma Cells Treated With Polyphenols.
Topics: Anthracyclines; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glioma; Humans; Inhibitory Concentration 50; Polyphenols; Tetrazolium Salts; Thiazoles | 2020 |
CAD/CAM scaffolds for bone tissue engineering: investigation of biocompatibility of selective laser melted lightweight titanium.
Topics: Biocompatible Materials; Bone and Bones; Bone Resorption; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Computer-Aided Design; Fibroblasts; Humans; In Vitro Techniques; Lasers; Materials Testing; Microscopy, Electron, Scanning; Osteoblasts; Osteosarcoma; Porosity; Regenerative Medicine; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Titanium | 2020 |
EPZ015666, a selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an antitumour effect in retinoblastoma.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunohistochemistry; Isoquinolines; Male; Mice; Mice, Nude; Protein-Arginine N-Methyltransferases; Pyrimidines; Real-Time Polymerase Chain Reaction; Retinal Neoplasms; Retinoblastoma; Tetrazolium Salts; Thiazoles; Time Factors; Transplantation, Heterologous | 2021 |
Gerardiins A-L and Structurally Related Phenanthrenes from the Halophyte Plant
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Magnoliopsida; Mice; Molecular Structure; Phenanthrenes; Plant Extracts; Salt-Tolerant Plants; Tetrazolium Salts; Thiazoles; Triple Negative Breast Neoplasms | 2020 |
Evaluation of 3D PLLA scaffolds coated with nano-thick collagen as carrier for hepatocytes.
Topics: Animals; Cell Line; Collagen; Extracellular Matrix; Fibroblasts; Hepatocytes; Male; Microscopy, Electron, Scanning; Nanostructures; Polyesters; Porosity; Rats; Rats, Sprague-Dawley; Swine; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2021 |
Liver Cancer Cells Uptake Labile Iron via L-type Calcium Channel to Facilitate the Cancer Cell Proliferation.
Topics: Biological Transport; Biophysics; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Cycle; Cell Proliferation; Chlorides; Disease Progression; Ferric Compounds; Hep G2 Cells; Hepatocytes; Humans; Iron; Kinetics; Liver Neoplasms; Neoplasm Metastasis; Signal Transduction; Tetrazolium Salts; Thiazoles | 2021 |
Paper-supported co-culture system for dynamic investigations of the lung-tropic migration of breast cancer cells.
Topics: Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Cell Survival; Coculture Techniques; Disease Progression; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Humans; Lung; Lung Neoplasms; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Paper; Signal Transduction; Stromal Cells; Tetrazolium Salts; Thiazoles; Tumor Microenvironment | 2021 |
Cytotoxicity of bismuth nanoparticles in the murine macrophage cell line RAW 264.7.
Topics: Animals; Bismuth; Cell Adhesion; Cell Cycle; Cell Proliferation; Cell Survival; DNA; DNA Damage; DNA Repair; Formazans; Lasers; Macrophages; Metal Nanoparticles; Mice; Phagocytosis; RAW 264.7 Cells; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2020 |
Bone tissue engineering gelatin-hydroxyapatite/graphene oxide scaffolds with the ability to release vitamin D: fabrication, characterization, and in vitro study.
Topics: Biocompatible Materials; Body Fluids; Bone and Bones; Bone Regeneration; Cell Adhesion; Cell Proliferation; Cell Survival; Diffusion; Drug Liberation; Durapatite; Gelatin; Graphite; Humans; In Vitro Techniques; Kinetics; Models, Theoretical; Osteogenesis; Porosity; Powders; Spectroscopy, Fourier Transform Infrared; Stem Cells; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Vitamin D | 2020 |
Dipeptidyl nitrile derivatives suppress the Trypanosoma cruzi in vitro infection.
Topics: Analysis of Variance; Animals; Antiparasitic Agents; Area Under Curve; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Haplorhini; Kidney; Nitriles; Proteolysis; Stereoisomerism; Tetrazolium Salts; Thiazoles; Trypanosoma cruzi | 2020 |
Design and evaluation of ciprofloxacin loaded collagen chitosan oxygenating scaffold for skin tissue engineering.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Survival; Chitosan; Ciprofloxacin; Collagen; Drug Carriers; Drug Delivery Systems; Erythrocytes; Fibroblasts; Humans; Male; Oxygen; Peroxides; Rats; Skin; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds; Wound Healing; X-Ray Diffraction | 2021 |
Expression of Estrogen Receptor-alpha in Nasal Polyps and the Effects of Dexamethasone on Estrogen Receptor-alpha Expression in RPMI 2650 Cells.
Topics: Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cell Survival; Dexamethasone; Endoscopy; Estrogen Receptor alpha; Fulvestrant; Humans; Immunohistochemistry; Keratins; Nasal Polyps; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Turbinates | 2020 |
GINS2 was regulated by lncRNA XIST/miR-23a-3p to mediate proliferation and apoptosis in A375 cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chromosomal Proteins, Non-Histone; Down-Regulation; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Silencing; HEK293 Cells; Humans; Melanocytes; Melanoma; MicroRNAs; RNA, Long Noncoding; Signal Transduction; Tetrazolium Salts; Thiazoles | 2021 |
MiR-182 inhibits proliferation, migration, invasion and inflammation of endometrial stromal cells through deactivation of NF-κB signaling pathway in endometriosis.
Topics: Cell Movement; Cell Proliferation; Computational Biology; Endometriosis; Endometrium; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Humans; Inflammation; Interleukin-6; Interleukin-8; MicroRNAs; Neoplasm Invasiveness; NF-kappa B p50 Subunit; Signal Transduction; Stromal Cells; Tetrazolium Salts; Thiazoles; Transcription Factor RelA; Transfection; Treatment Outcome; Wound Healing | 2021 |
LncRNA TP73-AS1 regulates miR-495 expression to promote migration and invasion of nasopharyngeal carcinoma cells through junctional adhesion molecule A.
Topics: Biopsy; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Disease Progression; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Protein Binding; Receptors, Cell Surface; RNA, Long Noncoding; Tetrazolium Salts; Thiazoles | 2021 |
MTT Test and Time-lapse Microscopy to Evaluate the Antitumor Potential of Nucleoside Analogues.
Topics: Antineoplastic Agents; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Microscopy; Nucleosides; Tetrazolium Salts; Thiazoles; Time-Lapse Imaging | 2021 |
Characterization and cytocompatibility of 3D porous biomimetic scaffold derived from rabbit nucleus pulposus tissue in vitro.
Topics: Animals; Biocompatible Materials; Biomimetics; Bone Marrow Cells; Cell Culture Techniques; Cell Proliferation; Cell Survival; Extracellular Matrix; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nucleus Pulposus; Porosity; Pressure; Rabbits; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2021 |
A simple "turn-on" fluorescence sensor for salicylaldehyde skeleton based on switch of PET-AIE effect.
Topics: Aldehydes; Chromatography, Thin Layer; Fluorescence; Fluorescent Dyes; Humans; Hydrogen Bonding; Hydroxyl Radical; Imines; Limit of Detection; Magnetic Resonance Spectroscopy; Mass Spectrometry; MCF-7 Cells; Medicine, Chinese Traditional; Microscopy, Fluorescence; Optical Imaging; Plant Bark; Plant Roots; Schiff Bases; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2021 |
Near-infrared fluorogenic receptor for selective detection of cysteine in blood serum and living cells.
Topics: Amino Acids; Cysteine; Fluorescent Dyes; HeLa Cells; Humans; Limit of Detection; Magnetic Resonance Spectroscopy; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Near-Infrared; Tetrazolium Salts; Thiazoles | 2021 |
Gelatin/carboxymethyl cellulose based stimuli-responsive hydrogels for controlled delivery of 5-fluorouracil, development, in vitro characterization, in vivo safety and bioavailability evaluation.
Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Cattle; Chlorocebus aethiops; Cross-Linking Reagents; Drug Delivery Systems; Drug Liberation; Fluorouracil; Gelatin; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; In Vitro Techniques; Microscopy, Electron, Scanning; Nanoparticles; Polymerization; Polymers; Porosity; Rabbits; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Vero Cells; X-Ray Diffraction | 2021 |
Co-delivery of cisplatin and oleanolic acid by silica nanoparticles-enhanced apoptosis and reverse multidrug resistance in lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Transplantation; Oleanolic Acid; Silicon Dioxide; Tetrazolium Salts; Thiazoles | 2021 |
Microwave-Assisted Rapid Green Synthesis of Gold Nanoparticles Using Seed Extract of
Topics: Anisotropy; Anti-Bacterial Agents; Antineoplastic Agents; Apiaceae; Biofilms; Cell Survival; Glutathione Transferase; Gold; Green Chemistry Technology; Hep G2 Cells; Humans; Light; Lipid Peroxidation; Listeria monocytogenes; Metal Nanoparticles; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Microwaves; Plant Extracts; Polysaccharides, Bacterial; Reactive Oxygen Species; Scattering, Radiation; Seeds; Serratia marcescens; Tetrazolium Salts; Thiazoles; X-Ray Diffraction | 2021 |
Synthesis of functionalized silk-coated chitosan-gold nanoparticles and microparticles for target-directed delivery of antitumor agents.
Topics: Antineoplastic Agents; Cell Survival; Chitosan; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Fibroins; Fluorescein; Folic Acid; Gold; Green Chemistry Technology; HeLa Cells; Humans; Hydrogels; Metal Nanoparticles; Microscopy, Fluorescence; Microspheres; Molecular Weight; Particle Size; Silk; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tetrazolium Salts; Thiazoles | 2021 |
Apigenin suppresses proliferation, invasion, and epithelial-mesenchymal transition of cervical carcinoma cells by regulation of miR-152/BRD4 axis.
Topics: Apigenin; Carcinoma; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; MicroRNAs; Neoplasm Invasiveness; Nuclear Proteins; Tetrazolium Salts; Thiazoles; Transcription Factors; Uterine Cervical Neoplasms | 2021 |
Cigarette smoke extract promotes DNA methyltransferase 3a expression in dendritic cells, inducing Th-17/Treg imbalance via the c-Jun/allograft inflammatory factor 1 axis.
Topics: Allografts; Animals; Anthracenes; Calcium-Binding Proteins; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Dendritic Cells; Disease Models, Animal; DNA Methyltransferase 3A; Enzyme Inhibitors; Male; Mice; Mice, Inbred BALB C; Microfilament Proteins; Proto-Oncogene Proteins c-jun; Pulmonary Disease, Chronic Obstructive; Signal Transduction; Smoke; Smoking; T-Lymphocytes, Regulatory; Tetrazolium Salts; Th17 Cells; Thiazoles | 2021 |
The use of a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide-based colorimetric assay in the viability analysis of the filamentous cyanobacterium Arthrospira platensis.
Topics: Biological Assay; Colorimetry; Spirulina; Tetrazolium Salts; Thiazoles | 2021 |
Comparison of Virosome vs. Liposome as drug delivery vehicle using HepG2 and CaCo2 cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Movement; Curcumin; Drug Delivery Systems; Excipients; Hep G2 Cells; Humans; Liposomes; Microbial Sensitivity Tests; Neoplasms; Nitric Oxide; Tetrazolium Salts; Thiazoles; Virosomes; Wound Healing | 2021 |
Nobiletin promotes the pyroptosis of breast cancer via regulation of miR-200b/JAZF1 axis.
Topics: Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Co-Repressor Proteins; DNA-Binding Proteins; Female; Flavones; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; NF-kappa B; Pyroptosis; Signal Transduction; Tetrazolium Salts; Thiazoles; Transfection | 2021 |
Lithium Chloride Protects against Sepsis-Induced Skeletal Muscle Atrophy and Cancer Cachexia.
Topics: Animals; Body Weight; Cachexia; Cell Differentiation; Cell Proliferation; Culture Media, Conditioned; Glycogen Synthase Kinase 3 beta; Inflammation; Lipopolysaccharides; Lithium Chloride; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Neoplasms; RAW 264.7 Cells; RNA, Small Interfering; Sepsis; SKP Cullin F-Box Protein Ligases; Tetrazolium Salts; Thiazoles | 2021 |
High cytotoxicity of betulin towards fish and murine fibroblasts: Is betulin safe for nonneoplastic cells?
Topics: 3T3 Cells; Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cytotoxins; Dimethyl Sulfoxide; Fibroblasts; Fishes; L-Lactate Dehydrogenase; Mice; Neutral Red; Solubility; Tetrazolium Salts; Thiazoles; Triterpenes | 2021 |
Inhibitory effect of Salvia coccinea on inflammatory responses through NF-κB signaling pathways in THP-1 cells and acute rat diabetes mellitus.
Topics: Active Transport, Cell Nucleus; Administration, Oral; Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Free Radicals; Glucose Tolerance Test; Glutathione; Glutathione Peroxidase; Glyburide; Humans; Inflammation; Lipid Peroxidation; NF-kappa B; Oxidative Stress; Pancreas; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Reactive Oxygen Species; Salvia; Signal Transduction; Tetrazolium Salts; Thiazoles; THP-1 Cells | 2021 |
A novel strategy of nanosized herbal Plectranthus amboinicus, Phyllanthus niruri and Euphorbia hirta treated TiO
Topics: Agar; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cell Line; Cell Survival; Euphorbia; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Mice; Microbial Sensitivity Tests; Models, Chemical; Nanotechnology; Phyllanthus; Plant Extracts; Plant Leaves; Plant Preparations; Plectranthus; Powders; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Titanium; X-Ray Diffraction | 2021 |
Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells.
Topics: Alternative Splicing; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Computational Biology; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Pyridines; Pyrimidines; RNA, Messenger; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor CHOP; Tumor Microenvironment; Up-Regulation | 2021 |
Bio-corrosion impacts on mechanical integrity of ZM21 Mg for orthopaedic implant application processed by equal channel angular pressing.
Topics: Absorbable Implants; Alloys; Bone Substitutes; Cell Line, Tumor; Cell Survival; Corrosion; Humans; Magnesium; Materials Testing; Orthopedics; Prostheses and Implants; Prosthesis Design; Scattering, Radiation; Stress, Mechanical; Tensile Strength; Tetrazolium Salts; Thiazoles | 2021 |
Salvia plebeia R. Br. polysaccharides (SPP) against RSV (respiratory syncytial virus) infection: Antiviral effect and mechanisms of action.
Topics: Animals; Antiviral Agents; Body Weight; Cell Line; Cytokines; Eating; Humans; Lung; Mice; Mice, Inbred BALB C; Plant Extracts; Polysaccharides; Respiratory Function Tests; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Ribavirin; Salvia; Tetrazolium Salts; Thiazoles; Toll-Like Receptors | 2021 |
SN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma.
Topics: Calorimetry, Differential Scanning; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Excipients; Glioblastoma; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Irinotecan; Lipids; Microscopy, Confocal; Nanoparticles; Nanostructures; Particle Size; Solubility; Solvents; Tetrazolium Salts; Thiazoles | 2021 |
Biological evaluation of antiproliferative and anti-invasive properties of an androstadiene derivative on human cervical cancer cell lines.
Topics: Androstadienes; Animals; Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Mice; Neoplasm Invasiveness; NIH 3T3 Cells; Propidium; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms; Wound Healing | 2021 |
MP-SeNPs; A Promising Cytokines Suppressor in Benzo[a]pyrene-Induced Mammal Tissue Injury in Rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Benzo(a)pyrene; Emulsions; Female; Humans; Lung; Magnetic Resonance Imaging; MCF-7 Cells; Moringa; Nanoparticles; Oxidative Stress; Phytochemicals; Rats; Reactive Oxygen Species; Temperature; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; X-Ray Diffraction | 2021 |
Biotransformation of the Phenolic Constituents from Licorice and Cytotoxicity Evaluation of Their Metabolites.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Aspergillus niger; Biotransformation; Cell Line, Tumor; Fermentation; Fungi; Glycyrrhiza; HT29 Cells; Humans; Hydrolysis; Inhibitory Concentration 50; MCF-7 Cells; Phenol; Phenols; Plant Extracts; Plant Roots; Powders; Rhizome; Spectrophotometry; Tetrazolium Salts; Thiazoles | 2021 |
In vitro phytochemical and anticancer activity of Misopates orontium L. and Dicliptera bupleuroides Nees.
Topics: Acanthaceae; Alkaloids; Carbohydrates; Cell Survival; Drug Screening Assays, Antitumor; Flavonoids; Glycosides; Hep G2 Cells; Humans; In Vitro Techniques; Indicators and Reagents; L-Lactate Dehydrogenase; Neutral Red; Oxazines; Plant Extracts; Plant Proteins; Plantaginaceae; Saponins; Tannins; Terpenes; Tetrazolium Salts; Thiazoles; Xanthenes | 2021 |
Electroceutical fabric lowers zeta potential and eradicates coronavirus infectivity upon contact.
Topics: Animals; Anti-Infective Agents; Body Fluids; Cell Line; Cell Survival; COVID-19; Electrochemistry; Fluoresceins; Humans; Hydrogen Peroxide; Kinetics; Nanoparticles; Propidium; SARS-CoV-2; Swine; Temperature; Tetrazolium Salts; Textiles; Thiazoles; Virion; Wound Healing | 2021 |
Comparative assessment of antimicrobial, antiradical and cytotoxic activities of cannabidiol and its propyl analogue cannabidivarin.
Topics: A549 Cells; Anti-Bacterial Agents; Anti-Infective Agents; Caco-2 Cells; Cannabidiol; Cannabinoids; Cannabis; Cell Line, Tumor; Cell Membrane; DNA; DNA Damage; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Free Radicals; Hep G2 Cells; Humans; Inhibitory Concentration 50; Neoplasms; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2021 |
Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment.
Topics: Actins; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytoskeleton; Drug Screening Assays, Antitumor; Humans; Minerals; Resins, Plant; Tetrazolium Salts; Thiazoles; Urinary Bladder Neoplasms | 2021 |
Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts.
Topics: Animals; Cell Survival; Cells, Cultured; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Homeostasis; Intercellular Signaling Peptides and Proteins; Lung; Mass Spectrometry; Mice; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-akt; Receptors, Aryl Hydrocarbon; Smoke; Tetrazolium Salts; Thiazoles; Tobacco Products | 2021 |
Pyrazoline derivatives as promising novel antischistosomal agents.
Topics: Animals; Antiparasitic Agents; Chalcones; Chemistry, Pharmaceutical; Chlorocebus aethiops; Computer Simulation; Drug Discovery; Haplorhini; Humans; Mice; Praziquantel; Pyrazoles; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Solvents; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vero Cells | 2021 |