thiazolidines has been researched along with proline in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (40.00) | 18.7374 |
| 1990's | 6 (10.91) | 18.2507 |
| 2000's | 8 (14.55) | 29.6817 |
| 2010's | 12 (21.82) | 24.3611 |
| 2020's | 7 (12.73) | 2.80 |
| Authors | Studies |
|---|---|
| Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K | 1 |
| Busiello, V; Cini, C; De Marco, C; di Girolamo, M | 1 |
| Arakawa, N; Otsuka, M; Sakashita, Y; Tsuda, M | 1 |
| Deutch, CE | 1 |
| Hara, H; Kurashima, Y; Miwa, M; Shinohara, K; Tanaka, Y; Tsuda, M | 1 |
| Higa, T; Kida, O; Kodama, K; Kondo, K; Morotomi, Y; Someya, N; Tanaka, K | 1 |
| Cho, T; Hagihara, Y; Hayashi, S; Kaminishi, H; Tsuno, N | 1 |
| Abe, K; Chiba, S; Goto, T; Kasai, Y; Omata, K; Sato, K; Seino, M; Tajima, J; Tanno, M; Yasujima, M | 1 |
| Abe, K; Tajima, J; Tanno, M; Yasujima, M; Yoshinaga, K | 1 |
| Funae, Y; Komori, T; Takada, T; Yamamoto, K | 1 |
| Fitzpatrick, PF; Massey, V | 1 |
| Hamilton, GA; Naber, N; Venkatesan, PP | 1 |
| Buckthal, DJ; Burns, CL; Hamilton, GA; Main, DE | 1 |
| Burdett, K; Elder, JB; Reed, PI; Smith, PL; Walters, CL | 1 |
| Csicsmann, J; Hutchinson, JS; Mendelsohn, FA | 1 |
| Di Nicolantonio, R; Hutchinson, JS; Takata, Y | 1 |
| DiNicolantonio, R; Doyle, AE; Hutchinson, JS; Mendelsohn, FA | 1 |
| Ganten, D; Lang, RE; Marin-Grez, M; Rascher, W; Unger, T; Yukimura, T | 1 |
| Abe, K; Omata, K; Tanno, M; Yasujima, M; Yoshinaga, K | 1 |
| Nakane, H; Nakane, Y; Ogihara, T; Saruta, T; Yasui, T; Yoshizawa, M | 1 |
| Bartsch, H; Crespi, M; Friesen, M; Lu, SH; Muñoz, N; O'Neill, I; Ohshima, H; Pignatelli, B | 1 |
| Díaz Gil, JJ; Trilla, C | 1 |
| Beames, DJ; Campbell, AJ; Edwards, SR; Montague, PE; Moore, RJ; Sheers, M | 1 |
| Kolodziej, SA; Lignon, MF; Marshall, GR; Martinez, J; Nikiforovich, GV; Skeean, R | 1 |
| Frederiks, WM; Gallagher, PT; Marx, F; Swann, BP; Van Noorden, CJ | 1 |
| Radomski, J; Wróbel, M; Włodek, L | 1 |
| Cutler, KO; Deutch, CE; Reese, LM | 1 |
| Arasappan, A; Chen, KX; Girijavallabhan, V; Njoroge, FG; Parekh, TN | 1 |
| LALLIER, R | 1 |
| BAVETTA, LA; BEKHOR, IJ; MOHSENI, Z | 1 |
| Carretero, OA; Cavasin, MA; Rhaleb, NE; Yang, XP | 1 |
| Che, Y; Marshall, GR | 1 |
| Cavelier, F; Marchand, D; Marraud, M; Martinez, J; Mbassi, P | 1 |
| Dalton, JT; Donkor, IO; Guan, N; Korukonda, R; Liu, J | 1 |
| Ban, M; Enomoto, H; Fujimura, K; Horiuchi, M; Miyake, Y; Mizuchi, M; Morikawa, Y; Suhara, H; Tsuji, F | 1 |
| Basra, S; Beavers, MP; Bennett, JS; Billings, PC; Choi, S; DeGrado, WF; Kahn, ML; Kulp, DW; McCarty, OJ; Miller, MW; Zou, Z | 1 |
| Ahn, IY; Magdaleno, A; Paes, LS; Silber, AM | 1 |
| Moeller, R; Reitz, G; Setlow, P; Wassmann, M | 1 |
| Alberts, J; Cantone, JL; Gao, M; Huang, XS; Leet, JE; Lemm, JA; Martin, SW; Meanwell, NA; Nower, PT; O'Boyle, DR; Romine, JL; Schroeder, DR; Serrano-Wu, MH; Snyder, LB; Sun, JH | 1 |
| Matsuda, T; Matsumura, E; Sakaguchi, M; Takaoka, M; Yoshimoto, T | 1 |
| Arisco, TM; Kumar, NN; Kutateladze, AG; Metzel, GA; Mukhina, OA; Valiulin, RA | 1 |
| Giulietti, AM; Perassolo, M; Quevedo, CV; Rodríguez Talou, J | 1 |
| Ahmed, M; Feyer, V; Ganesan, A; Plekan, O; Prince, KC; Wang, F | 1 |
| Akahoshi, F; Hayashi, Y; Kishida, H; Miyaguchi, I; Nabeno, M; Sakashita, H; Sonda, S; Takeuchi, M; Tanaka, Y; Yoshida, T | 1 |
| Sakaguchi, M; Suzuki, K; Takaoka, M; Tanaka, S; Yoshimoto, T | 1 |
| Kimura, AP; Maruyama, Y; Matsubara, S | 1 |
| Fu, P; Lai, J; Shen, YH; Sun, W; Zhang, Z | 1 |
| Kimura, AP; Maruyama, Y | 1 |
| Becker, DF; Campbell, AC; Gates, KS; Tanner, JJ | 1 |
| Bar-Even, A; Bruner, SD; Fiehn, O; Folz, JS; Hanson, AD; He, H; Li, Q; Patterson, JA; Wilson, MA | 1 |
| Fekri, LZ | 1 |
| Landmesser, A; Niessner, R; Pluym, N; Scherer, G; Scherer, M | 1 |
| Benz, CC; Ellerby, LM; Lopez-Ramirez, A; Loureiro, A; Mahoney, S; Scott, GK; Scott, M; Tanner, JJ | 1 |
| Bando, M; Ikeguchi, S; Kanazawa, M; Kikyo, F; Kondo, R; Mitsumori, M; Nishiuchi, R; Sakaguchi, M; Shiokawa, A; Tanaka, S; Yamada, Y | 1 |
| Becker, DF; Patel, SM; Seravalli, J; Stiers, KM; Tanner, JJ | 1 |
1 trial(s) available for thiazolidines and proline
| Article | Year |
|---|---|
A novel quantification method for sulfur-containing biomarkers of formaldehyde and acetaldehyde exposure in human urine and plasma samples.
Topics: Acetaldehyde; Biomarkers; Formaldehyde; Glycine; Humans; Limit of Detection; Methylation; Proline; Smoking; Sulfur; Tandem Mass Spectrometry; Thiazolidines | 2020 |
54 other study(ies) available for thiazolidines and proline
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2011 |
Action of thiazolidine-2-carboxylic acid, a proline analog, on protein synthesizing systems.
Topics: Amino Acids, Sulfur; Amino Acyl-tRNA Synthetases; Animals; Escherichia coli; Kinetics; Liver; Proline; Protein Biosynthesis; Puromycin; Rabbits; Rats; Reticulocytes; RNA, Transfer; Thiazolidines | 1979 |
Studies on endogenous formation of N-nitroso compounds in the guinea pig supplemented with proline or thioproline and sodium nitrate.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Gastric Acidity Determination; Guinea Pigs; Hydrogen-Ion Concentration; Male; Nitrates; Nitrosamines; Nitrosation; Nitroso Compounds; Proline; Thiazoles; Thiazolidines | 1992 |
Oxidation of L-thiazolidine-4-carboxylate by L-proline dehydrogenase in Escherichia coli.
Topics: Antioxidants; Cell Membrane; Escherichia coli; Kinetics; Oxidation-Reduction; Oxygen; Proline; Proline Oxidase; Spectrum Analysis; Thiazoles; Thiazolidines | 1992 |
Macrophage-mediated N-nitrosation of thioproline and proline.
Topics: Animals; Cell Line, Transformed; Macrophage Activation; Macrophages; Mice; Morpholines; Nitrosamines; Proline; Thiazoles; Thiazolidines | 1989 |
Comparison of the acute effects of three structurally different converting enzyme inhibitors (captopril, SA-446 and MK-421) on blood pressure, the renin-angiotensin system and the kallikrein-kinin system.
Topics: 3-Mercaptopropionic Acid; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Enalapril; Female; Humans; Kallikreins; Kinins; Male; Middle Aged; Oligopeptides; Proline; Renin-Angiotensin System; Sulfhydryl Compounds; Teprotide; Thiazolidines | 1985 |
[Effects of thiazolidine-4-carboxylic acid on germ tube formation and L-[14C(U)] proline uptake in Candida albicans].
Topics: Antineoplastic Agents; Candida albicans; Culture Media; Dose-Response Relationship, Drug; Proline; Thiazoles; Thiazolidines | 1985 |
Renal kallikrein-kinin system and the depressor effect of angiotensin converting enzyme inhibitors MK 421, SA 446, and captopril in rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diet, Sodium-Restricted; Dipeptides; Drug Evaluation, Preclinical; Enalapril; Hypertension; Kallikreins; Kinins; Male; Proline; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Thiazolidines | 1984 |
[Effects of 3 different angiotensin converting enzyme inhibitors, MK 421, SQ 14225 and SA 446 on renal function and blood pressure in patients with essential hypertension].
Topics: 3-Mercaptopropionic Acid; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dipeptides; Enalapril; Humans; Hypertension; Kidney; Middle Aged; Natriuresis; Potassium; Proline; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines | 1984 |
Effects of converting enzyme inhibitors on renin-angiotensin system in normal rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Kinetics; Lung; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines | 1984 |
Thiazolidine-2-carboxylic acid, an adduct of cysteamine and glyoxylate, as a substrate for D-amino acid oxidase.
Topics: Amino Acids, Sulfur; Animals; Cysteamine; D-Amino-Acid Oxidase; Glyoxylates; Kidney; Kinetics; Proline; Substrate Specificity; Swine; Thiazolidines | 1982 |
Inhibition of dopamine beta-hydroxylase by thiazoline-2-carboxylate, a suspected physiological product of D-amino acid oxidase.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Cattle; D-Amino-Acid Oxidase; Dopamine beta-Hydroxylase; Kinetics; Proline; Thiazolidines; Tyramine | 1982 |
Thiazolidine-2-carboxylate derivatives formed from glyoxylate and L-cysteine or L-cysteinylglycine as possible physiological substrates for D-aspartate oxidase.
Topics: Amino Acid Oxidoreductases; Animals; Aspartic Acid; Cattle; Cysteine; D-Aspartate Oxidase; Dipeptides; Glutamates; Glutamic Acid; Glyoxylates; Hydrogen-Ion Concentration; Proline; Substrate Specificity; Thiazolidines | 1984 |
Effect of H2 blockers on intragastric nitrosation as measured by 24-hour urinary secretion of N-nitrosoproline.
Topics: Adult; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Male; Middle Aged; Nitrosamines; Nitroso Compounds; Proline; Ranitidine; Thiazoles; Thiazolidines | 1984 |
Complex competitive and non-competitive inhibition of rat lung angiotensin-converting enzyme by inhibitors containing thiol groups: captopril and SA 446.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dipeptides; Enalapril; Lung; Proline; Rats; Sulfhydryl Compounds; Teprotide; Thiazolidines | 1981 |
A comparison of inhibition of angiotensin I conversion by three converting enzyme inhibitors in rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Enalapril; Female; Oligopeptides; Proline; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Teprotide; Thiazolidines | 1982 |
In vivo comparison of three orally active inhibitors of angiotensin-converting enzyme.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dipeptides; Enalapril; Female; Hypertension; Hypertension, Renovascular; Proline; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Thiazolidines | 1982 |
SA446, a new orally active converting enzyme inhibitor: antihypertensive action and comparison with captopril in stroke-prone spontaneously hypersensitive rats.
Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cerebrovascular Disorders; Hypertension; Kallikreins; Male; Natriuresis; Potassium; Proline; Rats; Renin; Sulfhydryl Compounds; Thiazolidines | 1982 |
Responses of the kallikrein-kinin system to angiotensin converting enzyme inhibitors in the rat.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Dipeptides; Enalapril; Kallikreins; Kinins; Male; Muscle, Smooth, Vascular; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sulfhydryl Compounds; Thiazolidines; Vasopressins | 1984 |
Effects of angiotensin I converting enzyme inhibitors on the renal excretory function, hemodynamics and renin release in isolated perfused rat kidney.
Topics: 3-Mercaptopropionic Acid; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Creatinine; Dipeptides; Enalapril; Hemodynamics; In Vitro Techniques; Kidney; Natriuresis; Perfusion; Potassium; Proline; Rats; Rats, Inbred Strains; Renin; Sulfhydryl Compounds; Thiazolidines; Vascular Resistance | 1983 |
Assessment of endogenous nitrosation in humans in relation to the risk of cancer of the digestive tract.
Topics: Ascorbic Acid; Dose-Response Relationship, Drug; Esophageal Neoplasms; Gastrointestinal Neoplasms; Humans; Kinetics; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Proline; Risk; Thiazoles; Thiazolidines | 1983 |
[Diminution of the rate of growth of HeLa cells caused by thioproline (Tp) and 2-aminothiazoline HCl (2-AT). Effect of L-proline].
Topics: Growth Inhibitors; HeLa Cells; Humans; Proline; Thiazoles; Thiazolidines | 1982 |
Fasciolicidal potential of proline analogues and proline biosynthesis inhibitors.
Topics: Animals; Azetidinecarboxylic Acid; Fasciola; Fascioliasis; Female; Hydroxylamine; Hydroxylamines; Proline; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1982 |
Ac-[3- and 4-alkylthioproline31]-CCK4 analogs: synthesis and implications for the CCK-B receptor-bound conformation.
Topics: Amino Acid Sequence; Animals; Cholecystokinin; Humans; Male; Models, Molecular; Molecular Sequence Data; Proline; Protein Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1995 |
In situ kinetic measurements of D-amino acid oxidase in rat liver with respect to its substrate specificity.
Topics: Animals; D-Amino-Acid Oxidase; Histocytochemistry; Kinetics; Liver; Male; Proline; Rats; Rats, Wistar; Substrate Specificity; Thiazolidines | 1993 |
The effect of 2-substituted thiazolidine-4(R)-carboxylic acids on non-protein sulphydryl levels and sulphurtransferase activities in mouse liver and brain.
Topics: Animals; Brain; Female; Liver; Mice; Proline; Sulfhydryl Compounds; Sulfurtransferases; Thiazoles; Thiazolidines; Thiosulfate Sulfurtransferase | 1993 |
Sensitivity of Escherichia coli to proline analogues during osmotic stress and anaerobiosis.
Topics: Anaerobiosis; Azetidinecarboxylic Acid; Betaine; Drug Resistance, Microbial; Drug Stability; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Osmotic Pressure; Proline; Thiazoles; Thiazolidines; Urinary Tract Infections | 1996 |
Novel dipeptide macrocycles from 4-oxo, -thio, and -amino-substituted proline derivatives.
Topics: Cyclization; Dipeptides; Drug Design; Proline; Thiazoles; Thiazolidines | 2002 |
[EFFECT OF THIAZOLIDINE-4-CARBOXYLIC ACID ON THE DEVELOPMENT OF THE EGG OF THE SEA URCHIN PARACENTROTUS LIVIDUS].
Topics: Animals; Echinodermata; Ovum; Paracentrotus; Pharmacology; Proline; Research; Sea Urchins; Thiazoles; Thiazolidines | 1964 |
INHIBITION OF PROLINE-C14 INCORPORATION INTO RAT LIVER RIBOSOMES BY THIAZOLIDINE-4-CARBOXYLIC ACID IN A CELL-FREE SYSTEM.
Topics: Carbon Isotopes; Cell-Free System; Hydroxyproline; Liver; Metabolism; Proline; Rats; Research; Ribosomes; RNA; Sulfur Isotopes; Thiazoles; Thiazolidines | 1965 |
Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dipeptides; Indoles; Kidney; Kidney Cortex; Male; Myocardium; Nitriles; Oligopeptides; Organ Specificity; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Thiazoles; Thiazolidines; Thymosin | 2004 |
Impact of cis-proline analogs on peptide conformation.
Topics: Binding Sites; Biopolymers; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Models, Statistical; Models, Theoretical; Molecular Conformation; Nitrogen; Normal Distribution; Peptides; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature; Tetrazoles; Thermodynamics; Thiazoles; Thiazolidines | 2006 |
Conformational studies of proline-, thiaproline- and dimethylsilaproline-containing diketopiperazines.
Topics: Diketopiperazines; Magnetic Resonance Spectroscopy; Molecular Conformation; Organosilicon Compounds; Piperazines; Proline; Protein Conformation; Thiazolidines | 2006 |
Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides.
Topics: Aldehydes; Calpain; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Activation; HeLa Cells; Humans; Molecular Structure; Proline; Pyrrolidinones; Stereoisomerism; Structure-Activity Relationship; Sulfones; Thiazoles; Thiazolidines | 2006 |
Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.
Topics: Animals; Carboxylic Acids; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Epoxide Hydrolases; Humans; Inhibitory Concentration 50; Leukotriene A4; Models, Chemical; Proline; Structure-Activity Relationship; Sulfhydryl Compounds; Thiazolidines | 2008 |
Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.
Topics: Allosteric Regulation; Animals; beta-Alanine; Fibrinolytic Agents; Humans; Integrin alpha2beta1; Mice; Mice, Inbred C57BL; Proline; Structure-Activity Relationship; Thiazolidines; Thrombosis | 2009 |
Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi.
Topics: Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Mice; Oxidative Stress; Proline; Temperature; Thiazolidines; Trypanosoma cruzi | 2009 |
Effect of radioprotective agents in sporulation medium on Bacillus subtilis spore resistance to hydrogen peroxide, wet heat and germicidal and environmentally relevant UV radiation.
Topics: Bacillus subtilis; Culture Media; Cysteine; Cystine; Hot Temperature; Hydrogen Peroxide; Proline; Radiation-Protective Agents; Spores, Bacterial; Thiazolidines; Ultraviolet Rays | 2011 |
Discovery of potent hepatitis C virus NS5A inhibitors with dimeric structures.
Topics: Alanine; Antiviral Agents; Carbamates; Cell Line; Chromatography, High Pressure Liquid; Diarrhea Viruses, Bovine Viral; Drug Discovery; Drug Resistance, Viral; Hepacivirus; Humans; Imidazoles; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Proline; Pyrrolidines; Stilbenes; Thiazolidines; Valine; Viral Nonstructural Proteins; Virus Replication | 2011 |
Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; Humans; Proline; Prolyl Oligopeptidases; RNA, Small Interfering; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazolidines | 2011 |
Rapid photoassisted access to N,O,S-polyheterocycles with benzoazocine and hydroquinoline cores: intramolecular cycloadditions of photogenerated azaxylylenes.
Topics: Azocines; Chemistry, Organic; Cyclization; Heterocyclic Compounds; Hydroquinones; Ketones; Nitrogen; Oxygen; Photochemistry; Proline; Stereoisomerism; Sulfur; Thiazolidines | 2011 |
Enhancement of anthraquinone production in Morinda citrifolia cell suspension cultures after stimulation of the proline cycle with two proline analogs.
Topics: Anthraquinones; Azetidinecarboxylic Acid; Cells, Cultured; Culture Media; Morinda; Phenols; Proline; Thiazolidines; Time Factors; Transcriptional Activation | 2012 |
Photoelectron spectra of some antibiotic building blocks: 2-azetidinone and thiazolidine-carboxylic acid.
Topics: Anti-Bacterial Agents; Azetidines; Photoelectron Spectroscopy; Proline; Quantum Theory; Thiazolidines | 2012 |
Fused bicyclic heteroarylpiperazine-substituted L-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group.
Topics: Animals; Bridged Bicyclo Compounds; Crystallography, X-Ray; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Humans; Male; Models, Molecular; Molecular Structure; Nitriles; Piperazines; Proline; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazolidines | 2012 |
Prolyl oligopeptidase inhibition-induced growth arrest of human gastric cancer cells.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Gene Deletion; Gene Knockdown Techniques; Humans; Proline; Prolyl Oligopeptidases; RNA Interference; Serine Endopeptidases; Stomach Neoplasms; Thiazolidines | 2014 |
Mouse prolyl oligopeptidase plays a role in trophoblast stem cell differentiation into trophoblast giant cell and spongiotrophoblast.
Topics: Animals; Cell Differentiation; Cell Survival; Female; Mice; Placenta; Pregnancy; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Stem Cells; Thiazolidines; Trophoblasts | 2017 |
Identification of two isoforms of Pop in the domestic silkworm, Bombyx mori: Cloning, characterization and expression analysis.
Topics: Angiotensin I; Animals; Bombyx; Cloning, Molecular; Gene Expression Profiling; Gene Expression Regulation, Developmental; Hydrogen-Ion Concentration; Indoles; Insect Proteins; Molting; Phylogeny; Proline; Prolyl Oligopeptidases; Protein Isoforms; Sequence Analysis, RNA; Serine Endopeptidases; Substrate Specificity; Temperature; Thiazolidines | 2018 |
A molecular mechanism of mouse placental spongiotrophoblast differentiation regulated by prolyl oligopeptidase.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; ErbB Receptors; Female; Gene Expression Regulation, Developmental; Mice; Placenta; Pregnancy; Proline; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazolidines; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1 | 2019 |
Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate.
Topics: Bacterial Proteins; Crystallography, X-Ray; Dinitrocresols; Enzyme Inhibitors; Kinetics; Models, Chemical; Oxidation-Reduction; Proline; Proline Oxidase; Sinorhizobium meliloti; Thiazolidines | 2020 |
Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli.
Topics: Aldehyde Oxidoreductases; Bacterial Proteins; Cysteine; Endopeptidases; Escherichia coli; Formaldehyde; Genes, Bacterial; Genome, Bacterial; Proline; Thiazolidines | 2020 |
s-Proline Covalented Silicapropyl Modified Magnetic Nanoparticles: Synthesis, Characterization, Biological and Catalytic Activity for the Synthesis of thiazolidin-4- ones.
Topics: Anti-Bacterial Agents; Bacteria; Catalysis; Magnetite Nanoparticles; Microbial Sensitivity Tests; Proline; Silicon Dioxide; Thiazolidines | 2020 |
N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
Topics: Alkynes; Animals; Antineoplastic Agents; ATPases Associated with Diverse Cellular Activities; Blood-Retinal Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Female; Glycine; Humans; Male; Mice; Mitochondria; Mitochondrial Proteins; Proline; Proline Oxidase; Thiazolidines; Transcriptome; Unfolded Protein Response | 2021 |
Prolyl oligopeptidase participates in the cytosine arabinoside-induced nuclear translocation of glyceraldehyde 3-phosphate dehydrogenase in a human neuroblastoma cell line.
Topics: Cell Death; Cell Nucleus; Cell Survival; Cytarabine; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Proline; Prolyl Oligopeptidases; Thiazolidines; Tumor Cells, Cultured | 2021 |
Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
Topics: Binding Sites; Cysteine; Humans; Kinetics; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Thiazolidines | 2021 |