thiazoles has been researched along with zankiren hydrochloride in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, WR; Barlow, J; Cohen, J; Kleinert, HD; Klinghofer, V; Kovar, P; Polakowski, J; Rosenberg, SH; Spina, K; Stein, HH | 1 |
| Fogal, SE; Loughnan, CL; Madwed, JB; Panzenbeck, MJ; Winquist, RJ | 1 |
| Fisher, ND; Hollenberg, N | 1 |
| Boger, RS; Glassman, HN; Guyene, TT; Kleinert, HD; Ménard, J; Moyse, DM | 1 |
| Dike, C; Fozailoff, A; Frishman, WH; Lin, C | 1 |
| Calzadilla, SV; Kleinert, HD; Kovar, PJ; Rosenberg, SH; Wessale, JL | 1 |
| Barlow, JL; Cohen, J; Condon, SL; Klinghofer, V; Kovar, P; Polakowski, J; Rosenberg, SH; Spina, KP; Stein, HH; Yao, Z | 1 |
| Cumin, F; Menard, J; Schnell, CR; Webb, RL; Wood, JM | 1 |
| Fisher, ND; Hollenberg, NK | 1 |
2 review(s) available for thiazoles and zankiren hydrochloride
| Article | Year |
|---|---|
Renin inhibition: a new approach to cardiovascular therapy.
Topics: Amides; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Hypertension; Imidazoles; Morpholines; Pharmacology, Clinical; Piperazines; Renin; Renin-Angiotensin System; Thiazoles | 1994 |
Renin inhibition: what are the therapeutic opportunities?
Topics: Dipeptides; Drug Design; Humans; Hypertension, Renal; Peptides; Piperazines; Renin; Renin-Angiotensin System; Thiazoles | 2005 |
2 trial(s) available for thiazoles and zankiren hydrochloride
| Article | Year |
|---|---|
Renal vascular responses to renin inhibition with zankiren in men.
Topics: Adult; Aldosterone; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Infusions, Intravenous; Male; Middle Aged; Natriuresis; Piperazines; Reference Values; Renal Plasma Flow; Renin; Thiazoles | 1995 |
Dose-dependent effects of the renin inhibitor zankiren HCl after a single oral dose in mildly sodium-depleted normotensive subjects.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Furosemide; Heart Rate; Humans; Hypotension, Orthostatic; Male; Piperazines; Renin; Renin-Angiotensin System; Thiazoles | 1995 |
5 other study(ies) available for thiazoles and zankiren hydrochloride
| Article | Year |
|---|---|
Discovery of a peptide-based renin inhibitor with oral bioavailability and efficacy.
Topics: Administration, Oral; Animals; Biological Availability; Hemodynamics; Peptides; Piperazines; Protease Inhibitors; Renin; Structure-Activity Relationship; Thiazoles | 1992 |
Captopril-induced hypotension is inhibited by the bradykinin blocker HOE-140 in Na(+)-depleted marmosets.
Topics: Administration, Oral; Animals; Blood Pressure; Bradykinin; Callithrix; Captopril; Female; Hypotension; Injections, Subcutaneous; Male; Piperazines; Renin; Sodium; Thiazoles | 1995 |
Effects of renin inhibitor A-72517 on hemodynamics and cardiac function in sodium-depleted dogs.
Topics: Animals; Blood Pressure; Diet, Sodium-Restricted; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Injections, Intravenous; Male; Piperazines; Protease Inhibitors; Radioimmunoassay; Renin; Thiazoles; Time Factors; Vasodilation | 1993 |
Studies directed toward the design of orally active renin inhibitors. 2. Development of the efficacious, bioavailable renin inhibitor (2S)-2-benzyl-3- [[(1-methylpiperazin-4-yl)sulfonyl]propionyl]-3-thiazol-4-yl-L-alanine amide of (2S,3R,4S)-2-amino-1-cyc
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Duodenum; Ferrets; Haplorhini; Humans; Intestinal Absorption; Liver; Molecular Structure; Piperazines; Rats; Renin; Structure-Activity Relationship; Thiazoles | 1993 |
Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats.
Topics: Administration, Oral; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Callithrix; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Female; Fumarates; Heart Rate; Imidazoles; Injections, Intravenous; Male; Piperazines; Rats; Rats, Inbred SHR; Renin; Telemetry; Tetrazoles; Thiazoles; Valine; Valsartan | 2005 |