Page last updated: 2024-08-21

thiazoles and xanthine

thiazoles has been researched along with xanthine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's5 (45.45)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Couch, RC; Griffin, TB; Hasegawa, M; Horiuchi, H; Komoriya, K; Kondo, S; Osada, Y1
Inoue, I; Katayama, S; Komoda, T; Miyazaki, T; Negishi, K; Sonoda, M; Takahashi, K1
Fujimura, Y; Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsui, T; Tsutsumi, Z; Yamamoto, T1
Horiuchi, H; Kaneko, H; Kasahara, Y; Kobayashi, M; Komoriya, K; Kondo, S; Nishimura, S; Ota, M1
Cao, Z; Li, Y; Tsang, M; Zhao, H1
MorĂ¡n, J; Valencia, A1
Grabowski, BA; Joseph-Ridge, N; Khosravan, R; Vernillet, L; Wu, JT1
Joseph-Ridge, N; Khosravan, R; Kukulka, MJ; Vernillet, L; Wu, JT1
Ben Mansour, H; Boubaker, J; Chekir Ghedira, L; Ghedira, K1
Iwasaki, H; Kishi, S; Matsuda, Y; Nakamura, T; Ookura, M; Tai, K; Takai, M; Ueda, T; Yamauchi, T; Yoshida, A1
Azzolin, VF; Barbisan, F; da Cruz Jung, IE; da Cruz, IBM; da Cunha, BSN; do Prado-Lima, PA; Duarte, MMMF; Duarte, T; Ribeiro, EE; Turra, BO1

Trials

2 trial(s) available for thiazoles and xanthine

ArticleYear
Pharmacokinetics, pharmacodynamics and safety of febuxostat, a non-purine selective inhibitor of xanthine oxidase, in a dose escalation study in healthy subjects.
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Models, Biological; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase

2006
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Biotransformation; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Protein Binding; Sex Factors; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase; Young Adult

2008

Other Studies

9 other study(ies) available for thiazoles and xanthine

ArticleYear
Hypouricemic effect of allopurinol and the novel xanthine oxidase inhibitor TEI-6720 in chimpanzees.
    European journal of pharmacology, 1993, Dec-21, Volume: 250, Issue:3

    Topics: Administration, Oral; Allopurinol; Animals; Dose-Response Relationship, Drug; Febuxostat; Female; Gout; Macaca mulatta; Male; Pan troglodytes; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

1993
Troglitazone has a scavenging effect on reactive oxygen species.
    Biochemical and biophysical research communications, 1997, Jun-09, Volume: 235, Issue:1

    Topics: Antioxidants; Chromans; Cytochrome c Group; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydrogen Peroxide; Iron; Molecular Structure; Neutrophils; Pioglitazone; Reactive Oxygen Species; Spin Labels; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E; Xanthine; Xanthine Oxidase; Xanthines

1997
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
    Pharmacology, 2000, Volume: 60, Issue:1

    Topics: Allopurinol; Biological Transport; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Febuxostat; Humans; Hypoxanthine; Inosine; Lung Neoplasms; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Pentosyltransferases; Purines; Pyrimidine Phosphorylases; Thiazoles; Tumor Cells, Cultured; Uracil; Uridine; Xanthine; Xanthine Oxidase

2000
A comparative study on the hypouricemic activity and potency in renal xanthine calculus formation of two xanthine oxidase/xanthine dehydrogenase inhibitors: TEI-6720 and allopurinol in rats.
    Research communications in molecular pathology and pharmacology, 1999, Volume: 104, Issue:3

    Topics: Allantoin; Allopurinol; Animals; Enzyme Inhibitors; Febuxostat; Kidney Calculi; Male; Rats; Rats, Inbred Strains; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase

1999
Induction of endogenous antioxidants and phase 2 enzymes by alpha-lipoic acid in rat cardiac H9C2 cells: protection against oxidative injury.
    Biochemical and biophysical research communications, 2003, Oct-24, Volume: 310, Issue:3

    Topics: Animals; Antioxidants; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Models, Biological; Models, Chemical; Myocardium; Oxidative Stress; Oxygen; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Thioctic Acid; Time Factors; Xanthine

2003
Reactive oxygen species induce different cell death mechanisms in cultured neurons.
    Free radical biology & medicine, 2004, May-01, Volume: 36, Issue:9

    Topics: Animals; Biological Assay; Calcium; Caspases; Catalase; Cell Culture Techniques; Cell Death; Cell Survival; Cerebellum; Ionomycin; Neurons; Oxidative Stress; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Xanthine; Xanthine Oxidase

2004
Polar extracts from (Tunisian) Acacia salicina Lindl. Study of the antimicrobial and antigenotoxic activities.
    BMC complementary and alternative medicine, 2012, Apr-10, Volume: 12

    Topics: Acacia; Anti-Bacterial Agents; Antioxidants; Bacteria; Benzothiazoles; Flavonoids; Free Radical Scavengers; Mutagens; Plant Extracts; Plant Leaves; Sulfonic Acids; Superoxides; Thiazoles; Xanthine

2012
Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Aged; Allopurinol; Antineoplastic Agents; Creatinine; Enzyme Inhibitors; Febuxostat; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Humans; Hypoxanthine; Male; Middle Aged; Pilot Projects; Prospective Studies; Thiazoles; Tumor Lysis Syndrome; Uric Acid; Xanthine; Xanthine Oxidase

2014
The Influence of a Xanthine-Catechin Chemical Matrix on in vitro Macrophage-Activation Triggered by Antipsychotic Ziprasidone.
    Inflammation, 2019, Volume: 42, Issue:3

    Topics: Animals; Antipsychotic Agents; Caffeine; Catechin; Cell Proliferation; Complex Mixtures; Inflammation; Macrophage Activation; Macrophages; Mice; Oxidative Stress; Paullinia; Piperazines; RAW 264.7 Cells; Theobromine; Thiazoles; Xanthine

2019