Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and warfarin

thiazoles has been researched along with warfarin in 519 studies

Research

Studies (519)

TimeframeStudies, this research(%)All Research%
pre-19906 (1.16)18.7374
1990's9 (1.73)18.2507
2000's35 (6.74)29.6817
2010's406 (78.23)24.3611
2020's63 (12.14)2.80

Authors

AuthorsStudies
Remmer, H; Snyder, R1
Berlin, I; Cournot, A; Sallord, JC; Singlas, E1
Prino, G; Santamaria, L1
Hume, M; Kuriakose, TX; Turner, RH; Zuch, L1
Freeman, RG; Knox, JM; Murtishaw, W1
Gibson, TE; Parfitt, JW1
Boyd, MR; Boyer, PL; Currens, MJ; Hughes, SH; McMahon, JB1
Beamand, JA; Lake, BG; Mistry, H; Price, RJ; Renwick, AB; Wield, PT1
Ito, K; Kasai, H; Miyashita, Y2
Bluhmki, E; Busch, U; Heinzel, G; Hoffmann, J; Su, CA; Türck, D1
Goldberg, MP; Handran, SD; Hyrc, K; Rothman, SM1
Häcker, G; Roloff, S; Wilhelm, S1
Morreale, AP; Plowman, BK1
Funae, Y; Funayama, M; Green, C; Inoue, K; Kamataki, T; Kimura, K; Kinoshita, M; Kodama, T; Nagashima, K; Nunoya, K; Yokoi, T1
Maliwal, BP; Thompson, RB; Zeng, HH1
Knaggs, AR1
Doss, SH; Louca, NA; Wardakhan, WW1
Jimenez, JA; Jones, G1
Krishna, DR; Rao, VR; Srimanth, K1
Deligeorgiev, TG; Katerinopoulos, HE; Liepouri, F; Savakis, C; Veneti, Z1
García-Báez E, EV; Höpfl, H; Martínez-Martínez, FJ; Padilla-Martínez, II1
Nauen, R; Rauch, N1
Gorman, AM; Quigney, DJ; Samali, A1
Greger, M; Landberg, T; Lindberg, S1
Crowell, KJ; Fattorusso, R; Forino, M; Jung, D; Pellecchia, M1
Baek, SH; Chai, KY; Chung, HT; Jang, SI; Kim, YJ; Kwak, GB; Kwak, KC; Kwon, TO; Lee, WY; Yun, YG1
Karguppikar, AM; Mulimani, BG; Nadaf, YF; Raikar, US; Renuka, CG; Soudagar, MK1
Friis, C; Gillberg, M; Skaanild, MT1
Erlanson, DA; Gordon, EM; Shiau, TP1
Dong, Y; Feng, SS1
Hadjipavlou-Litina, D; Kontogiorgis, CA; Luo, Y; Xu, Y1
Draeger, G; Hey-Hawkins, E; Jashari, A; Mikhova, B; Popovski, E1
Aryal, S; Chaudhari, AA; Dharmaraj, N; Kim, HY; Kim, WD; Park, SY; Prabu, P1
Alesiani, D; Bei, R; Canini, A; Cicconi, R; Mattei, M; Montesano, C1
Li, HL; Liu, RH; Shen, YH; Su, J; Wu, ZJ; Zhang, C; Zhang, WD1
Hoshide, S; Kanou, M; Mukoyoshi, M; Muroga, H; Nishimura, S; Taniguchi, K; Umeda, S1
Chen, S; Lui, K; Mori, T; Tamura, T; Zhou, D1
Cheng, G; Chung, SJ; Cui, F; Kim, DD; Kim, IW; Shim, CK; Shim, WS; Yang, R; Yang, SG1
Hiwatari, K; Hoffman, RM; Kataoka, M; Kimura, R; Ma, H; Masaoka, Y; Sakuma, S; Shoji, Y; Tachikawa, H; Tang, L; Yamashita, S; Yang, Z; Yano, T1
Gao, X; Hu, K; Jiang, X; Li, J; Lu, W; Shen, Y; Zhang, Q1
Cheng, G; Chung, SJ; Cui, FD; Han, X; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Yang, R1
Hara, H; Hironaka, K; Inokuchi, Y; Shimazawa, M; Takeuchi, H; Tozuka, Y1
Anitha, P; Feng, SS; Gan, CW; Mei, L; Zhou, W1
Cavalli, R; Civra, A; Donalisio, M; Ferruti, P; Lembo, D; Ranucci, E; Trotta, F1
Jackson, AS; Rossignol, JF; Vets, E1
Baudoin, C; Féron, C; Koyama, S; Novotny, MV; Soini, HA; Wiesler, D1
Bakowsky, U; Kissel, T; Sitterberg, J; Trapani, A1
Kang, KH; Kim, MM; Kim, SK; Kong, CS; Seo, Y1
Ishibashi, T; Tsutsumi, N1
Fujisawa, T; Hara, H; Hironaka, K; Inokuchi, Y; Shimazawa, M; Takeuchi, H; Tozuka, Y; Tsuruma, K1
Trynda-Lemiesz, L; Wiglusz, K1
Chen, H; Fan, W; He, Q; Kuai, R; Qin, Y; Tang, J; Tang, W; Wu, Y; Yao, N; Yuan, W; Zhang, Z1
Ahn, H; Choi, KH; Kim, AJ; Kim, KB; Kim, KH; Lee, EB; Son, IJ1
Chen, H; He, Q; Liu, J; Qin, Y; Sun, X; Tang, J; Tang, L; Tang, W; Yin, Y; Zhang, Z1
Lopes, RD; Mahaffey, KW; Piccini, JP1
Bellvert, F; Bodo, B; Chaouch, S; Didierlaurent, L; Garmier, M; Kauffmann, S; Langlois-Meurinne, M; Marie, A; Massoud, K; Noctor, G; Saindrenan, P; Simon, C1
Cao, F; Cheng, J; Jin, X; Ping, Q; Sun, M; Xu, Y; You, W; Yuan, D1
Bolden, G; Chinta, DM; Dash, S; Graves, RA; Hazari, S; Kishore, V; Mandal, TK; Pamujula, S1
Feng, SS; Gan, CW1
Connolly, SJ; Jin, J; Kastrissios, H; Kunitada, S; Mendell, J; Patel, I; Rohatagi, S; Salazar, D; Weitz, JI1
Cormier, R; Labruère, R; Sicard, R; Turos, E; West, L1
Agarwal, S; Beck-Broichsitter, M; Gessler, T; Greiner, A; Kissel, T; Nguyen, J; Schmehl, T; Seeger, W; Thieme, M1
Ding, B; Ding, X; Fan, W; Gao, J; Gao, S; Hou, X; Wang, X; Wu, X; Zhang, M; Zhang, W; Zhu, Q1
Antman, EM; Bocanegra, T; Braunwald, E; Crugnale, SE; Giugliano, RP; Hanyok, J; McCabe, CH; Mercuri, M; Patel, I; Ruff, CT; Salazar, D; Shi, M1
Chen, SA; Chung, N; Chung, WS; Jeon, HK; Lai, WT; Lee, TH; Lien, LM; Tse, HF1
Fleita, DH; Mohareb, RM; Sakka, OK1
Gore, JC; Higashino, H; Hiwatari, K; Kataoka, M; Kimura, R; Kumagai, H; Masaoka, Y; Nakamura, K; Pham, W; Sakuma, S; Tachikawa, H; Yamashita, S; Yano, T1
Feng, SS; Kulkarni, SA1
Jethva, PN; Makwana, PK; Roy, I1
Gasco, MR; Gasco, P; Lettiero, B; Masserini, M; Miserocchi, G; Panariti, A; Rivolta, I; Sesana, S1
Chao, X; Chen, T; Fei, Z; Huo, J; Liu, W; Luo, P; Qu, Y; Xie, K; Zhang, L1
Michinaka, Y; Mitragotri, S1
Kong, D; Wan, Y; Wang, Z; Yang, C; Zhou, Z; Zhu, J1
Clavreul, A; Huynh, NT; Menei, P; Montero-Menei, C; Passirani, C; Roger, M; Schiller, P; Vessières, A1
Chiang Boey, FY; Huang, CL; Kumar, S; Loo, JS; Steele, TW; Venkatraman, SS; Widjaja, E1
Criscione, JM; Jun, L; Lavik, EB; Robinson, R; Tsai, JC; Viviano, SR; Williams, CA1
Hiwatari, K; Hoffman, RM; Pham, W; Sakuma, S; Yamashita, S1
Bui, T; Geldenhuys, W; Harrison, K; Mbimba, T; Sutariya, V1
Arshad, A; Bagley, MC; Lam, CK; Mohamad, S; Osman, H; Zahariluddin, AS1
Liu, R; Liu, W; Song, N; Tu, Q; Wang, J; Zhang, Y1
Chirico, G; Collini, M; D'Alfonso, L; Lettiero, B; Miserocchi, G; Panariti, A; Rivolta, I; Sironi, L1
Govedarica, B; Kristl, J; Pajk, S; Pečar, S; Plajnšek, KT; Srčič, S1
Booth, CJ; Cu, Y; Saltzman, WM1
Huang, A; Makhlof, A; Ping, Q; Takeuchi, H; Tozuka, Y1
Dehghan, G; Emami, S; Foroumadi, A; Khoobi, M; Ramazani, A; Shafiee, A1
Di Pasquale, G; Riva, L1
Chen, L; Chen, Y; Fang, X; Gao, X; Gu, J; Jiang, X; Jiang, Y; Law, K; Ren, Q; Ren, X; Sha, X; Wang, X; Xin, H1
Chen, H; Chen, J; Gao, X; Gu, G; Hu, Q; Jiang, X; Liu, Z; Pang, Z; Song, Q; Xia, H; Yao, L; Zeng, N1
Chen, Z; Liang, H; Pan, Y; Wang, H; Yi, X; Zhang, Y; Zou, B1
Gao, H; Jiang, X; Lu, W; Pang, Z; Yin, Q; Yu, Y1
Chen, J; Feng, C; Jiang, X; Liu, Q; Shao, X; Shen, Y; Zhang, C; Zhang, Q1
Feng, SS; Kulkarni, SA; Muthu, MS; Xiong, J1
Chen, H; Gao, X; Guo, L; Jiang, X; Lai, R; Li, J; Qiu, M; Wu, H; Yan, X; Zhang, Q1
Chen, H; Huang, L; Jiang, L; Liu, R; Ma, Y; Mei, L; Zeng, X; Zheng, Y1
Inagi, T; Makino, K; Suzuki, K; Terada, H; Terashima, H; Tomoda, K1
Chen, J; Feng, C; Gao, X; Jiang, X; Liu, Q; Shen, Y; Wang, L; Zhang, Q1
Dai, W; He, B; He, Z; Wang, J; Zhang, Q; Zhang, X; Zhao, S1
Abd El-Wahab, AH; Ahmed, KA; Bedair, AH; Eid, FA; El-Agrody, AM; Khafagy, MM; Mohamed, HM1
Chen, H; Fan, W; Hai, L; He, Q; Li, X; Qin, Y; Tang, J; Wu, Y; Xie, F; Yao, N; Yuan, M; Zhang, Q1
Deng, L; Tang, C; Tu, L; Wei, M; Wu, C; Xu, T; Xu, Y; Zou, Q1
He, Z; Wang, J; Yuan, L; Zhang, Q; Zhang, X; Zhao, S1
Barooah, N; Bhasikuttan, AC; Mohanty, J; Pal, H1
Chen, X; Li, H; Niu, J; Ping, Q; Xiao, Y1
Kamijo, S; Kawasaki, T1
Appold, L; Fokong, S; Jorge, S; Kiessling, F; Koczera, P; Lammers, T; Resch-Genger, U; Storm, G; Theek, B; van Zandvoort, M; Wu, Z1
Bommer, WJ1
Halperin, JL; Varughese, CJ1
Edo, N; Honda, Y; Kamisato, C; Kita, A; Morishima, Y; Shibano, T; Tsuji, N1
Inoue, H; Kawai, Y; Koretsune, Y; Matsumoto, M; Ogawa, S; Uchiyama, S; Yamaguchi, T; Yamashita, T; Yasaka, M1
Arif, M; Iqbal, J; Mahmood, S; Muddassar, M; Raza, A; Raza, R; Saeed, A1
Lip, GY; Marín, F; Roldán, V1
Chen, C; Deng, J; Guo, T; Hu, Y; Jiang, X; Li, L; Mei, H; Pang, Z; Shen, S; Shi, W; Wang, H; Zhang, B1
Chen, H; Chen, J; Gao, X; Gu, G; Hu, Q; Jiang, X; Liu, Z; Pang, Z; Song, Q; Tu, Y; Xia, H; Yao, L1
Guo, D; Hou, L; Mao, P; Mo, L; Xiao, X; Yang, X1
Jin, Y; Li, B; Ma, W; Xu, A; Xu, G; Yao, M; Ying, J1
Gomha, SM; Khalil, KD1
Mendell, J; Noveck, RJ; Shi, M1
Alver, O; Kurien Thomas, K; Rajasekharan, KN; Reshmy, R; Sajan, D; Selvanayagam, S; Sulekha, A1
Brenner, B; Hoffman, R1
Furugohri, T; Honda, Y; Kamisato, C; Morishima, Y; Shibano, T1
Gore, JC; Hiwatari, K; Kataoka, M; Kimura, R; Kumagai, H; Liu, EH; McBride, J; Nakamura, K; Pham, W; Sakuma, S; Tachikawa, H; Wilson, KJ1
Koziński, M; Kubica, A; Kubica, J; Navarese, EP; Obońska, K1
Du, W; Fan, Y; He, B; Wang, J; Wang, X; Yuan, L; Zhang, H; Zhang, Q; Zhang, X; Zheng, N1
Valle Bernad, R1
Martin, EN; Money, SR; Shamoun, FE1
Hirota, K; Kawamoto, T; Makino, K; Nakajima, T; Terada, H1
Aggarwal, R; Gupta, GK; Kaushik, D; Kaushik, P; Kumar, S1
Nile, SH; Park, SW; Patel, JK; Patel, RV1
Chen, H; Chen, J; Gao, X; Gu, G; Hu, Q; Jiang, M; Jiang, X; Kang, T; Liu, Z; Miao, D; Pang, Z; Song, Q; Tu, Y; Yao, L1
Feng, SS; Muthu, MS; Raju, A1
Dai, W; Du, W; Fan, Y; He, B; Jia, Z; Wang, J; Wang, X; Yu, C; Yuan, L; Zhang, H; Zhang, Q; Zhang, X1
Chen, H; Guan, M; Liu, L; Wang, J; Zhang, Q; Zhang, T; Zhou, Z1
Liu, C; Liu, X; Lu, W; Wei, G; Xie, C; Zhang, W1
Gu, L; Zou, T1
Büller, H; Mercuri, M; Prins, M; Raskob, G; Schwocho, L; Segers, A; Shi, M; van Kranen, R1
Badimón, JJ; Briongos Figuero, S; García Santos-Gallego, C1
Chen, J; Jiang, X; Liu, Q; Qian, Y; Shao, X; Zha, Y; Zhang, C; Zhang, Q; Zhang, X; Zheng, X1
Spyropoulos, AC; Turpie, AG1
Chen, H; Dong, Y; Huang, H; Zhang, J; Zhang, W; Zhao, T; Zhu, J1
Honda, Y; Kamisato, C; Morishima, Y; Shibano, T1
Aneja, KR; Chandak, N; Jain, S; Kaushik, D; Kaushik, P; Kumar, P; Sharma, C; Sharma, PK; Varshney, P1
Tahara, K; Takeuchi, H; Ying, L1
Huang, L; Liu, T; Mei, L; Ouyang, C; Tao, W; Wang, Z; Xiong, Q; Zeng, X1
Lopes, RD; Newby, LK; Truffa, AA1
Agnelli, G; Becattini, C; Franco, L1
Bao, XH; Fink-Baldauf, IM; Fukazawa, T; Hao, H; Maeda, Y; Matsuoka, J; Nakajima, M; Naomoto, Y; Nelson, S; Okui, T; Papoian, R; Seibel, W; Shimo, T; Takaoka, M; Takigawa, N; Tomono, Y; Whitsett, JA; Yamatsuji, T1
Gao, H; Hu, Y; Jiang, X; Xiong, Y; Yang, J; Yu, L; Zhang, S1
Liang, WQ; Lv, YY; Sun, XY; Wu, S; Xiang, ZQ1
Gao, H; Jiang, X; Liu, Q; Pang, Z; Yang, Z; Zhang, S1
Antman, EM; Betcher, J; Braunwald, E; Ezekowitz, MD; Giugliano, RP; Grip, LT; Halperin, JL; Hanyok, JJ; Koretsune, Y; Mercuri, M; Murphy, SA; Patel, I; Patel, SP; Ruda, M; Ruff, CT; Ruzyllo, W; Shi, M; Špinar, J; Waldo, AL; Weitz, JI; Wiviott, SD1
Einecke, D1
Sprynger, M1
Dai, WB; He, B; Wang, XQ; Yu, C; Zhang, H; Zhang, Q1
Mitka, M1
Schulman, S1
Bredenbeck, J; Messmer, AT; van Wilderen, LJ1
Blanco, MD; Fernández, A; Olmo, R; Pérez, E; Teijón, JM1
Giugliano, RP; Gonzalez-Quesada, CJ1
Chen, H; Chen, J; Feng, X; Gao, X; Hu, Q; Huang, M; Jiang, D; Jiang, X; Kang, T; Pang, Z; Song, Q; Yao, L; Zhang, X1
Cao, S; Gao, H; Jiang, X; Pang, Z; Yang, Z; Zhang, S1
Giugliano, RP; Plitt, A3
Fan, M; Guo, W; Li, D; Men, W; Wei, X; Xu, Y; Yin, D; Zhu, JA1
Cavalieri, F; Ciaffardini, F; Crestini, C; Melone, F; Mosesso, P; Tortora, M1
Ballazhi, L; Dräger, G; Huwiler, A; Imeri, F; Jashari, A; Mikhova, B; Popovski, E; Shabani, A1
Yorozu, T1
Davidson, N; Galloway, SW; Lai, A; Thachil, J1
Li, Y; Liu, X; Sun, F; Teng, L; Wang, D; Zhao, J; Zhou, Y1
Duan, YW; En, D; Guo, Y; Li, CW; Li, J; Peng, MJ; Suzenet, F; Yang, XF; Yin, B1
Hürlimann, D; Noll, G; Noll, S1
Erga, SR; Frette, Ø; Hamre, B; Kristoffersen, AS1
Prabhakaran, S; Veltkamp, R1
Benjaminsen, J; Fenaroli, F; Griffiths, G; Hildahl, J; Kolstad, T; Meijer, AH; Nyström, B; Roos, N; Skjeldal, FM; Ulanova, L; van der Vaart, M; Westmoreland, D1
Antman, EM; Betcher, JM; Braunwald, E; Dave, J; Deenadayalu, N; Duggal, A; Giugliano, RP; Grip, LT; Lowe, C; Mercuri, M; Murphy, SA; Rost, NS; Ruff, CT; Shi, M; Silverman, S; Wiviott, SD1
Angeli, F; Lip, GY; Reboldi, G; Verdecchia, P1
Liberato, NL; Marchetti, M; Quaglini, S; Rognoni, C1
Bao, X; Chu, QC; Gao, M; Guan, X; Jiang, N; Liu, KX; Tian, Y; Xu, H; Zhang, CH1
Cai, XX; Fu, N; Lin, YF; Peng, Q; Shao, XR; Wei, XQ; Zhang, S; Zhang, T; Zhang, ZR1
Bongu, NR; Kocheril, AG; Turagam, MK; Velagapudi, P1
Antman, EM; Betcher, J; Braunwald, E; Cange, AL; Crompton, AE; Curt, V; Deenadayalu, N; Giugliano, RP; Grip, L; Mercuri, M; Murphy, SA; Ruff, CT1
Aleksic, M; Boyd, P; Cubberley, R; O'Connor, D; Parkinson, E; Skipp, P1
Bang, OY; Chung, CS; Kim, GM; Kim, JS; Kim, SJ; Lee, KH; Lee, MJ; Park, YK; Ryoo, S; Yoon, CH1
Giugliano, RP1
Jaggi, M; Joshi, V; Negi, LM; Ronodip, K; Talegaonkar, S1
Cormode, DP; Latourette, MT; Mallet, CL; Parys, M; Schwartz-Duval, AS; Shapiro, EM; Shuboni, DD; Swy, ER1
Das, S; Dhar, SK; Govindaraju, T; Kumar, M; Kundu, TK; Narayanaswamy, N; Pati, SK; Samanta, PK; Sharma, R1
Madhusudhana, S; Qasem, A; Strasser, KM1
Chandrasekaran, S; Enoch, IV; Sameena, Y1
Ezekowitz, MD; Kent, AP1
Al-Halhouli, AT; Bartels, J; Behrends, S; Büttgenbach, S; Dahl, K; Dietzel, A; Finke, JH; Krull, R; Lorenz, T; Müller-Goymann, CC; Peterat, G; Pretor, S; Reichl, S1
An, G; Fleisher, B; Shao, J; Unum, J1
Banothu, J; Bavantula, R; Crooks, PA; Gali, R; Gondru, R; Velivela, Y1
Ballow, C; Battegay, M; Chan, TS; Cooper, C; Girlich, B; Haschke, M; Kashuba, AD; Kort, J; Lang, B; Li, Y; O'Brien, D; Sabo, JP; Seibert, E; Ting, N; Tweedie, D; Zhang, W1
Astete, CE; Damann, KE; Muse, ES; Patel, NR; Sabliov, CM1
Baneham, S; Cox, D; Kirby, BP; Moollan, A; O'Donnell, A; Ozgul, M; Pabari, RM; Ramtoola, Z1
Chen, HZ; Dong, X; Fang, C; Gao, YG; Guan, YY; Liu, HJ; Liu, YR; Lu, Q; Luan, X; Wang, C; Yang, SC1
Amin, A; Deitelzweig, S1
Amin, A; Bruno, A; Lin, J; Lingohr-Smith, M; Trocio, J1
Arepally, GM; Ortel, TL1
Comparelli, R; Cordero, H; Cuesta, A; Di Franco, C; Esteban, MA; Mandracchia, D; Morcillo, P; Trapani, A1
Antman, EM; Braunwald, E; Cermak, O; Giugliano, RP; Grip, LT; Kania, G; Mercuri, MF; Murphy, SA; O'Donoghue, ML; Ruff, CT; Rutman, H; Shi, M1
Granger, CB; Pokorney, SD1
Gazioglu, I; Kucukislamoglu, M; Kurt, BZ; Sonmez, F1
Gore, JC; Hiwatari, K; Ikejima, T; Kitamura, T; Koike, S; Kumagai, H; McClure, R; Mohri, K; Pham, W; Sakuma, S; Shimosato, M; Tobita, E1
Loffredo, L; Perri, L; Violi, F1
Oberhofer, E1
Antman, EM; Braunwald, E; Deenadayalu, N; Giugliano, RP; Lee, J; Mega, JL; Mercuri, MF; Murphy, SA; Nordio, F; Ruff, CT; Sabatine, MS; Vandell, AG; Walker, JR1
Wu, AH1
Ballazhi, L; Ibrahimi, I; Imeri, F; Jashari, A; Mikhova, B; Mladenovska, K; Popovski, E1
Hogg, K; Weitz, JI; Yeh, CH1
Du, Z; Lang, M; Zhang, Y1
Huynh, K1
Chen, C; Chen, X; Fan, Z; Fang, X; Liang, H; Pang, X; Qi, Y; Sha, X; Yu, Z1
Fukazawa, T; Ishida, N; Kato, K; Maeda, Y; Matsumoto, K; Naomoto, Y; Shimo, T; Takigawa, N; Whitsett, JA; Yamatsuji, T1
Dişli, A; Gümüş, M; Koca, İ; Özgür, A; Tutar, Y1
Harenberg, J; Krejczy, M; Lip, GY; Obermann, K; Wehling, M1
Ito, M; Nakamura, M; Yamada, N2
Boakye, CH; Patel, K; Singh, M1
Al-Saadi, N; Ellenbogen, K; Ezekowitz, M; Goette, A; Jin, J; Lanz, H; Lip, GY; Mercuri, M; Merino, J; Zamoryakhin, D1
Wright, GE1
Antman, EM; Atar, D; Braunwald, E; Camm, AJ; Giugliano, RP; Heidbuchel, H; Murphy, SA; Ruff, CT; Steffel, J1
Conen, D1
MegallyAbdo, NY; Mohareb, RM1
Abe, K; Büller, H; Kimura, T; Lee, LH; Mercuri, M; Miyazaki, K; Nakamura, M; Oh, D; Segers, A; Wang, C; Wang, YQ; Yin, WH1
Dai, W; Deng, F; He, B; Wang, X; Yu, C; Zhang, H; Zhang, Q; Zheng, Y1
Ding, J; Feng, M; Guan, W; Wang, F; Wang, H1
Chen, J; Long, M; Su, C; Wang, L; Zhuang, X1
Hong, K; Lane, DA; Lau, YC; Lip, GY; Senoo, K; Xiong, Q1
Wang, L; Xiao, H1
Hijazi, Z; Oldgren, J1
McCormack, PL1
Antman, EM; Braunwald, E; Geller, BJ; Giugliano, RP; Hanyok, JJ; Jin, J; Mercuri, M; Murphy, SA; Ruff, CT1
Iemsam-Arng, J; Ketchart, O; Rattana-Amron, T; Tapaneeyakorn, S; Wutikhun, T1
Colonna, P; Rubboli, A1
Ameloot, M; Berden, M; D'Olieslaeger, L; Deville, S; Ethirajan, A; Penjweini, R1
Eikelboom, J; Weitz, JI1
Hierrezuelo, JM; Molina-Bolivar, JA; Ruiz, CC1
Goldhaber, SZ; Kwong, WJ; Preblick, R; White, RH1
Dzeshka, MS; Lip, GY1
McBane, RD; Schaefer, JK; Wysokinski, WE1
Antman, EM; Cohen, DJ; Giugliano, RP; Kwong, WJ; Li, H; Magnuson, EA; Ruff, CT; Vilain, K; Wang, K1
Didier, R; Escarcega, RO; Kiramijyan, S; Koifman, E; Lipinski, MJ; Torguson, R; Waksman, R1
Cheung, BM; Kumana, CR; Lauder, IJ; Siu, DC; Tse, HF1
Keloglu, N; Sohier, J; Trimaille, T; Verrier, B1
Chen, X; Chu, B; He, Y; Huang, Y; Long, C; Ou, C; Qian, Z; Qu, Y; Zhang, L1
Katti, DS; Mahaling, B1
Wei, MY; Wu, CB; Xu, YH; Zou, Q1
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Chen, H; Deng, Y; Li, S; Tong, Y; Zou, L1
Lv, H; Xie, Z; Zhang, Z1
Antman, EM; Bergmark, BA; Braunwald, E; Chung, N; Giugliano, RP; Lanz, HJ; Park, S; Ruff, CT; Shi, M1
Patel, MH; Sawant, KK1
Ashraf, Z; Channar, PA; Iqbal, J; Irum, H; Larik, FA; Lecka, J; Mahmood, A; Saeed, A; Sévigny, J; Shabir, G; Zaib, S1
Cohen, AA; De Caterina, R; de Groot, JR; Ezekowitz, MD; Goette, A; Heidbuchel, H; Jin, J; Le Heuzey, JY; Lip, GYH; Melino, M; Merino, JL; Merkely, B; Themistoclakis, S; Winters, SM1
Bai, X; Dong, B; Huang, G; Liu, J; Liu, M; Lv, J; Song, H; Sun, J; Sun, L; Sun, X; Xu, L; Xu, W; Zhang, G; Zhang, L1
Bagde, A; Kutlehria, S; Patel, N; Singh, M1
Ahsan Halim, S; Al-Harrasi, A; Csuk, R; Ibrar, A; Khan, A; Khan, I; Mehsud, S; Saeed, A1
Antman, EM; Bergmark, BA; Braunwald, E; Giugliano, RP; Kamphuisen, PW; Kuder, JF; Lanz, HJ; Mercuri, MF; Nordio, F; Ruff, CT; Wiviott, SD1
Anderson, CF; Chakroun, RW; Cui, H; Mitrut, RE; Su, H1
Antman, EM; Corbalan, R; Duris, T; Giugliano, RP; Juul-Möller, S; Kerschnitzki, M; Nicolau, AM; Nicolau, JC; Nordio, F; Ruff, CT; Trevisan, M; Voitk, J; Zierhut, W1
Pastori, D; Pignatelli, P; Violi, F1
Duong, HD; Rhee, JI; Shin, Y1
Al-Saady, N; Cohen, A; Goette, A; Goudev, A; Hjortshøj, SP; Huber, K; Jin, J; Kozieł, M; Lip, GYH; Melino, M; Winters, SM1
Du, W; Huang, S; Wen, L; Xu, H; Zhu, C1
Chaiyakunapruk, N; Dilokthornsakul, P; Hollingworth, W; Jahan, NK; Kongpakwattana, K; Lai, NM; Nathisuwan, S; Ng, SS1
Ali, H; Hanley, DF; Marsh, EB; Nyquist, PA; Shin, SS; Ziai, WC1
Ahmad, Z; Al-Qawasmeh, RA; Al-Tel, TH; Hersi, F; Jaber, AM; Omar, HA; Zaher, DM1
Bachmann, P; Böhm, M; Custodis, F; Millenaar, D; Schirmer, SH1
Zidek, W1
De Caterina, R; Goette, A; Huber, K; Jin, J; Kozieł, M; Lip, GYH; Melino, M; Merino, JL1
Cai, Y; Gao, X; Shuai, Q; Sun, X; Xu, J; Xu, Z; Zhu, F1
Cui, X; Dou, Y; Gao, Y; He, S; Li, Z; Qiao, F; Xu, L; Zhong, S1
Barillari, G; Bortoluzzi, C; Dentali, F; Giorgi, M; Orabona, R; Pacetti, E; Sciatti, E; Zaffaroni, M1
De Caterina, R; Goette, A; Heidbuchel, H; Huber, K; Jin, J; Lip, GYH; Merino, JL1
Ho, KH; Leng, G; van Hove, M1
Acar, RD; Akgün, T; Camm, AJ; Emren, V; Kanat, S; Karacağlar, E; Kepez, A; Kul, Ş; Özel, E; Şimşek, E; Tülüce, K; Türk, UÖ; Yakar Tülüce, S1
Liu, X; Xu, ZX; Yu, P; Yuan, P; Zhu, WG1
Jenkins, A; Katada, J; Kohsaka, S; Li, B; Mardekian, J; Saito, K; Terayama, Y1
Bauersachs, J; Berliner, D; Flierl, U; Schäfer, A1
Bansal, V; Bhagat, S; Gupta, N; Jangid, AK; Kulhari, H; Pooja, D; Singh, M; Singh, S1
Cheng, X; Chu, ZW; Hu, R; Liu, H; Lv, XH; Xia, DG1
Fukushima, K; Hagiwara, N; Haruki, S; Jujo, K; Kikuchi, Y; Minami, Y; Murasaki, K; Ogawa, H; Sekiguchi, H; Tanaka, H; Yoshida, A1
Huang, M; Liu, X; Ma, J; Ye, C; Zeng, C; Zeng, J1
Doyama, H; Fujishiro, M; Fujita, T; Hasatani, K; Hatta, W; Hiasa, Y; Hikichi, T; Igarashi, K; Iguchi, M; Inoue, T; Kawaguchi, K; Kitamura, K; Kuribayashi, S; Mikami, T; Morita, Y; Nishida, T; Nishikawa, J; Oda, I; Sumiyama, K; Sumiyoshi, T; Tomida, H; Tsuji, Y; Uraoka, T; Yada, T; Yamamoto, K; Yanagitani, A; Yoshio, T1
Eichinger, S; Grosso, MA; Kyrle, PA; Lin, M; Shi, M1
Duong, HD; Rhee, JI; Sohn, OJ1
Lopes, DG; Schipp, B; Siepmann, T; Tamayo, A1
Choe, WS; Choi, EK; Han, KD; Jung, JH; Kwon, S; Lee, E; Lee, SR; Lip, GYH; Oh, S1
Kawano, Y; Tamura, A; Yamamoto, E1
Abbas, EMH; Abdel-Aziz, MM; Farghaly, TA; Harras, MF; Masaret, GS; Omar, MA1
Antman, EM; Braunwald, E; Cohen, DJ; Giugliano, RP; Kwong, WJ; Li, H; Magnuson, EA; Ruff, CT; Vilain, K1
Yavelov, IS1
Aprile, F; Breccia, M; Chistolini, A; Fiori, L; Gioia, S; Lucani, B; Merli, M; Riggio, O; Serrao, A1
Arya, R; Brown, A; Byrne, R; Coles, E; Czuprynska, J; Gee, E; Patel, JP; Patel, R; Rea, C; Roberts, LN; Saul, G; Speed, V; Vadher, B1
Clegg, A; Gale, CP; Hall, M; Kunadian, V; Rockwood, K; Searle, SD; Todd, O; Wilkinson, C; Wu, J1
Avorn, J; Gagne, JJ; Kesselheim, AS; Rome, BN1
Egred, M; Farag, M; Gorog, DA; Gue, YX; Spinthakis, N1
Bu, Y; Wang, L; Xu, T; Yang, L; Yu, Z; Zhang, J; Zhang, Y; Zhou, H; Zhu, X1
Antman, EM; Braunwald, E; Giugliano, RP; Lanz, HJ; Nelson, SE; Norden, AD; Park, JG; Rost, NS; Ruff, CT; Silverman, S; Singhal, AB1
Liang, X; Lin, Z; Liu, M; Xie, W1
Fu, Q; He, Z; Liu, Y; Wang, Y; Zhang, G; Zhang, Z1
Oh, HJ; Park, BJ; Ryu, KH; Yoon, BH1
Dufès, C; Laskar, P; Mullin, M; Sakpakdeejaroen, I; Somani, S1
Bradley, SM; Gosch, KL; Hess, PL; Jani, SM; Maddox, TM; Michael Ho, P; Varosy, PD; Virani, SS1
Cui, X; Dou, Y; Fang, Y; Gao, Y; He, S; Meng, Q; Zhong, S1
Drabik, L; Undas, A1
Grove, EL; Larsen, TB; Lip, GYH; Nielsen, PB; Ording, AG; Skjøth, F; Søgaard, M1
Ansari, MF; Cheng, Y; Hu, C; Hu, Y; Pan, G; Yadav Bheemanaboina, RR; Yu, C; Zhang, J; Zhou, C1
Jensen, M; Lip, GY; Nielsen, PB; Ording, AG; Søgaard, M1
Duong, HD; Rhee, JI1
Ciszkowicz, E; Creaven, B; Jenkins, H; Kamiński, D; Karcz, D; Lecka-Szlachta, K; Matwijczuk, A; Miłoś, A; Radomski, P; Ślusarczyk, L; Starzak, K1
Abdo, NYM; Ibrahim, RA; Mohareb, RM; Samir, EM1
Duggal, A; Grosso, MA; Kakkar, T; Kotsuma, M; Lanz, H; Shi, M; Yin, O1
Antman, EM; Bonaca, MP; Braunwald, E; Cunningham, JW; Giugliano, RP; Grosso, MA; Halperin, JL; Lanz, HJ; Murphy, SA; Ruff, CT; Weitz, JI; Wiviott, SD1
Chang, C; Hou In Chou, O; Iltaf Satti, D; Ka Chung Wai, A; Lee, S; Liu, T; Liu, X; Roever, L; Tai Loy Lee, T; Tak Wong, W; Tse, G; Zhang, Q; Zhou, J1
Antman, EM; Berger, D; Braunwald, E; Chen, C; Eisen, A; Gencer, B; Giugliano, RP; Grip, LT; Lanz, H; Murphy, SA; Nordio, F; Ruff, CT1
Akao, M; Fukuzawa, M; Hayashi, T; Imamura, Y; Kuroda, M; Lip, GYH; Nose, T; Ogimoto, A; Okumura, K; Tamiya, E; Taura, J; Yamashita, T1
Geng, RX; Hu, CF; Hu, CS; Li, S; Yang, XC; Zhang, PL; Zhou, CH1
Bhatia, M; Kapoor, A; Kumar, A; Kumar, P; Kumar, S1
Akao, M; Betsuyaku, T; Hayashi, T; Hirabayashi, K; Imamura, Y; Mikami, T; Okawa, K; Okumura, K; Tanizawa, K; Watanabe, S; Yamashita, T1
Angeli, A; Arifuddin, M; Chirra, H; Goud, NS; Newaskar, V; Shaik, AB; Sigalapalli, DK; Supuran, CT; Thacker, PS1
Abdel-Aziem, A; Elsharabasy, SA; Sayed, MT1

Reviews

85 review(s) available for thiazoles and warfarin

ArticleYear
Classes of hepatic microsomal mixed function oxidase inducers.
    Pharmacology & therapeutics, 1979, Volume: 7, Issue:2

    Topics: Animals; Barbiturates; Cell Nucleus; Coumarins; Cytochrome P-450 Enzyme System; Environmental Pollutants; Enzyme Induction; Flavonoids; Humans; Insecticides; Liver; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Polycyclic Compounds; Protein Biosynthesis; Thiazoles; Time Factors; Xanthines

1979
List of the photodynamic substances.
    Research progress in organic, biological and medicinal chemistry, 1972, Volume: 3 Pt 1

    Topics: Acridines; Alkaloids; Anthraquinones; Anti-Bacterial Agents; Benzhydryl Compounds; Benzothiadiazines; Coumarins; Light; Naphthalenesulfonates; Nitroso Compounds; Oxazines; Oxidation-Reduction; Phenazines; Phenothiazines; Photochemistry; Polycyclic Compounds; Pyrones; Quinolines; Stilbenes; Sulfonamides; Thiazines; Thiazoles; Trityl Compounds; Vitamins; Xanthenes

1972
The biosynthesis of shikimate metabolites.
    Natural product reports, 2001, Volume: 18, Issue:3

    Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Animals; Anthranilate Synthase; Bacteria; Betalains; Catalysis; Chorismate Mutase; Coumarins; Flavonoids; Hydro-Lyases; Indoleacetic Acids; Indoles; Intramolecular Transferases; Lignans; Molecular Structure; Penicillium; Phenylalanine; Phenylpropionates; Phosphorus-Oxygen Lyases; Prephenate Dehydratase; Prephenate Dehydrogenase; Pristinamycin; Pyrrolnitrin; Quaternary Ammonium Compounds; Quinones; Shikimic Acid; Staurosporine; Tannins; Thiazoles; Thyroxine; Tryptophan; Tyrosine; Ubiquinone

2001
Oral factor Xa inhibitors for the prevention of stroke in atrial fibrillation.
    Current opinion in cardiology, 2010, Volume: 25, Issue:4

    Topics: Anticoagulants; Atrial Fibrillation; Benzamides; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Thromboembolism; Warfarin

2010
Lectin-immobilized fluorescent nanospheres for targeting to colorectal cancer from a physicochemical perspective.
    Current drug discovery technologies, 2011, Dec-01, Volume: 8, Issue:4

    Topics: Acetamides; Animals; Colonoscopy; Colorectal Neoplasms; Coumarins; Drug Delivery Systems; Fluorescent Dyes; Humans; Nanospheres; Peanut Agglutinin; Polystyrenes; Polyvinyls; Thiazoles

2011
[Thromboembolic prophylaxis 2011: is warfarin on the wane?].
    Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:9

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzamides; Benzimidazoles; beta-Alanine; Clinical Trials, Phase III as Topic; Dabigatran; Evidence-Based Medicine; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Rivaroxaban; Thiazoles; Thiophenes; Thromboembolism; Treatment Outcome; Warfarin

2011
Current and future alternatives to warfarin for the prevention of stroke in atrial fibrillation.
    Critical pathways in cardiology, 2012, Volume: 11, Issue:2

    Topics: Anticoagulants; Antithrombin Proteins; Atrial Appendage; Atrial Fibrillation; Benzimidazoles; Chemoprevention; Dabigatran; Fibrinolytic Agents; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2012
Prevention of stroke in patients with atrial fibrillation: anticoagulant and antiplatelet options.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2012, Volume: 35, Issue:1

    Topics: Anticoagulants; Antithrombins; Aspirin; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clopidogrel; Dabigatran; Hemorrhage; Humans; Morpholines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Thrombolytic Therapy; Ticlopidine; Warfarin

2012
The promise of novel direct oral anticoagulants.
    Best practice & research. Clinical haematology, 2012, Volume: 25, Issue:3

    Topics: Anticoagulants; Antithrombins; Azetidines; Benzimidazoles; Benzylamines; Clinical Trials, Phase III as Topic; Dabigatran; Factor Xa Inhibitors; Heparin, Low-Molecular-Weight; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thiophenes; Thrombin; Thromboembolism; Warfarin

2012
[New oral anticoagulants - sunset for warfarin in therapy of atrial fibrillation].
    Kardiologia polska, 2012, Volume: 70, Issue:10

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Electric Countershock; Factor Xa Inhibitors; Humans; Kidney Failure, Chronic; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2012
The novel anticoagulants: the surgeons' prospective.
    Surgery, 2013, Volume: 153, Issue:3

    Topics: Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Blood Loss, Surgical; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Surgical Procedures, Operative; Thiazoles; Thiophenes; Venous Thromboembolism; Warfarin

2013
[Improvements in oral anticoagulant therapy for atrial fibrillation].
    Medicina clinica, 2013, Dec-07, Volume: 141, Issue:11

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Azetidines; Benzimidazoles; Benzylamines; beta-Alanine; Dabigatran; Embolism; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Treatment Outcome; Warfarin

2013
Venous thromboembolism management: where do novel anticoagulants fit?
    Current medical research and opinion, 2013, Volume: 29, Issue:7

    Topics: Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Factor X; Heparin; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thiophenes; Thrombin; Venous Thromboembolism; Vitamin K; Warfarin

2013
Alternatives to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a look back at the state of the field in 2012.
    Postgraduate medicine, 2013, Volume: 125, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2013
New oral anticoagulants for the treatment of venous thromboembolism.
    Best practice & research. Clinical haematology, 2013, Volume: 26, Issue:2

    Topics: Administration, Oral; Adult; Aged; Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Drug Administration Schedule; Humans; Middle Aged; Morpholines; Pulmonary Embolism; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Thiazoles; Thiophenes; Venous Thromboembolism; Warfarin

2013
New oral anticoagulant agents - general features and outcomes in subsets of patients.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Clinical Trials, Phase III as Topic; Dabigatran; Hemorrhage; Humans; Morpholines; Patient Selection; Pyrazoles; Pyridines; Pyridones; Risk; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Treatment Outcome; Venous Thromboembolism; Warfarin

2014
Edoxaban: Review of pharmacology and key phase I to III clinical trials.
    Journal of cardiovascular pharmacology and therapeutics, 2014, Volume: 19, Issue:5

    Topics: Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Treatment Outcome; Venous Thrombosis; Warfarin

2014
[Prevention of venous thromboembolism and anticoagulant therapy].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:3

    Topics: Anesthesia, Epidural; Anticoagulants; Biomarkers; Diagnostic Imaging; Fibrin Fibrinogen Degradation Products; Heparin; Humans; Intraoperative Complications; Perioperative Care; Postoperative Complications; Practice Guidelines as Topic; Pulmonary Embolism; Pyridines; Risk Factors; Thiazoles; Venous Thromboembolism; Venous Thrombosis; Warfarin

2014
Novel anticoagulants vs warfarin for stroke prevention in atrial fibrillation.
    Cardiovascular & hematological disorders drug targets, 2014, Volume: 14, Issue:1

    Topics: Animals; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Drug Discovery; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2014
Target-specific oral anticoagulants: practice issues for the clinician.
    Hospital practice (1995), 2014, Volume: 42, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Drug Interactions; Humans; Medication Adherence; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Venous Thromboembolism; Warfarin

2014
Switching between oral anticoagulants.
    Hospital practice (1995), 2014, Volume: 42, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; United States; Warfarin

2014
Target-specific oral anticoagulants and the hospitalist.
    Hospital practice (1995), 2015, Volume: 43, Issue:1

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Clinical Trials, Phase III as Topic; Dabigatran; Factor Xa Inhibitors; Hospitalists; Humans; International Normalized Ratio; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Venous Thrombosis; Warfarin

2015
Changing practice of anticoagulation: will target-specific anticoagulants replace warfarin?
    Annual review of medicine, 2015, Volume: 66

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Factor Xa Inhibitors; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Venous Thromboembolism; Warfarin

2015
Impact of new oral anticoagulants on gastrointestinal bleeding in atrial fibrillation: A meta-analysis of interventional trials.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2015, Volume: 47, Issue:5

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Gastrointestinal Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Risk Factors; Rivaroxaban; Thiazoles; Warfarin

2015
Overview of the new oral anticoagulants: opportunities and challenges.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:5

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dabigatran; Dose-Response Relationship, Drug; Drug Administration Schedule; Factor Xa Inhibitors; Female; Humans; Male; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Sensitivity and Specificity; Stroke; Thiazoles; Thiophenes; Thromboembolism; Warfarin

2015
Anticoagulation therapy. Optimal dosages and genotypes for edoxaban therapy.
    Nature reviews. Cardiology, 2015, Volume: 12, Issue:5

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Thiazoles; Warfarin

2015
Current management of venous thromboembolism in Japan: Current epidemiology and advances in anticoagulant therapy.
    Journal of cardiology, 2015, Volume: 66, Issue:6

    Topics: Anticoagulants; Fondaparinux; Heparin; Humans; Japan; Polysaccharides; Pulmonary Embolism; Pyridines; Quality of Life; Risk Factors; Thiazoles; Venous Thromboembolism; Venous Thrombosis; Warfarin

2015
Efficacy and Safety of Edoxaban in Nonvalvular Atrial Fibrillation: A Meta-analysis of Randomized Controlled Trials.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2015, Volume: 24, Issue:12

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Treatment Outcome; Warfarin

2015
Non-vitamin K antagonist oral anticoagulants (NOACs) in patients with concomitant atrial fibrillation and heart failure: a systemic review and meta-analysis of randomized trials.
    European journal of heart failure, 2015, Volume: 17, Issue:11

    Topics: Anticoagulants; Atrial Fibrillation; Heart Failure; Hemorrhage; Humans; Pyridines; Randomized Controlled Trials as Topic; Risk Adjustment; Stroke; Thiazoles; Treatment Outcome; Warfarin

2015
[Large studies of NOAC shows good and safe stroke protection].
    Lakartidningen, 2015, Sep-08, Volume: 112

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyrazoles; Pyridines; Pyridones; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Warfarin

2015
Edoxaban: a review in nonvalvular atrial fibrillation.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2015, Volume: 15, Issue:5

    Topics: Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Risk Factors; Stroke; Thiazoles; Warfarin

2015
Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Dabigatran; Embolism; Factor Xa Inhibitors; Female; Humans; Intracranial Hemorrhages; Male; Pyrazoles; Pyridines; Pyridones; Research Design; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
Edoxaban for reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:17

    Topics: Atrial Fibrillation; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Embolism; Factor Xa Inhibitors; Humans; Pyridines; Risk; Stroke; Thiazoles; Thromboembolism; Vitamin K; Warfarin

2015
How to choose appropriate direct oral anticoagulant for patient with nonvalvular atrial fibrillation.
    Annals of hematology, 2016, Volume: 95, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; beta-Alanine; Clinical Decision-Making; Dabigatran; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Warfarin

2016
Comparison of Watchman device with new oral anti-coagulants in patients with atrial fibrillation: A network meta-analysis.
    International journal of cardiology, 2016, Feb-15, Volume: 205

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Dabigatran; Defibrillators, Implantable; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Thiazoles; Warfarin

2016
Non-vitamin K Oral Anticoagulants Versus Warfarin for Patients with Atrial Fibrillation: Absolute Benefit and Harm Assessments Yield Novel Insights.
    Cardiovascular therapeutics, 2016, Volume: 34, Issue:2

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Humans; Male; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
Suboptimal Use of Oral Anticoagulants in Atrial Fibrillation: Has the Introduction of Direct Oral Anticoagulants Improved Prescribing Practices?
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016, Volume: 16, Issue:3

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Blood Coagulation Factors; Dabigatran; Dose-Response Relationship, Drug; Evidence-Based Medicine; Factor Xa Inhibitors; Humans; Medication Errors; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
New anticoagulants for the treatment of venous thromboembolism.
    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia, 2016, Volume: 42, Issue:2

    Topics: Anticoagulants; Dabigatran; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Time Factors; Venous Thromboembolism; Warfarin

2016
Comparative Effectiveness of Interventions for Stroke Prevention in Atrial Fibrillation: A Network Meta-Analysis.
    Journal of the American Heart Association, 2016, 05-20, Volume: 5, Issue:5

    Topics: Anticoagulants; Atrial Appendage; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Intracranial Hemorrhages; Network Meta-Analysis; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
Nonvitamin K Anticoagulant Agents in Patients With Advanced Chronic Kidney Disease or on Dialysis With AF.
    Journal of the American College of Cardiology, 2016, 06-21, Volume: 67, Issue:24

    Topics: Anticoagulants; Atrial Fibrillation; Creatinine; Dabigatran; Glomerular Filtration Rate; Hemorrhage; Humans; Kidney; Kidney Failure, Chronic; Pyrazoles; Pyridines; Pyridones; Renal Dialysis; Renal Insufficiency, Chronic; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
[Anticoagulation for patients with non-valvular atrial fibrillation].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:4

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Factor Xa Inhibitors; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thrombolytic Therapy; Warfarin

2016
Bleeding with Direct Oral Anticoagulants vs Warfarin: Clinical Experience.
    The American journal of medicine, 2016, Volume: 129, Issue:11S

    Topics: Administration, Oral; Anticoagulants; Antidotes; Atrial Fibrillation; Clinical Trials, Phase III as Topic; Dabigatran; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2016
Efficacy and Safety of Novel Oral Anticoagulants in Patients With Atrial Fibrillation and Heart Failure: A Meta-Analysis.
    JACC. Heart failure, 2016, Volume: 4, Issue:11

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Cardiovascular Diseases; Cause of Death; Dabigatran; Embolism; Factor Xa Inhibitors; Heart Failure; Hemorrhage; Humans; Intracranial Hemorrhages; Mortality; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Warfarin

2016
Bleeding with direct oral anticoagulants vs warfarin: clinical experience.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:11S

    Topics: Anticoagulants; Clinical Trials, Phase III as Topic; Dabigatran; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2016
Comparative Efficacy of Clinical Events Prevention of Five Anticoagulants in Patients With Atrial Fibrillation (A Network Meta-Analysis).
    The American journal of cardiology, 2017, Feb-15, Volume: 119, Issue:4

    Topics: Anticoagulants; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Mortality; Myocardial Infarction; Network Meta-Analysis; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
Edoxaban: A direct oral anticoagulant.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, 02-01, Volume: 74, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Drug Monitoring; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Stroke; Thiazoles; Venous Thromboembolism; Warfarin

2017
Edoxaban in Atrial Fibrillation and Venous Thromboembolism-Ten Key Questions and Answers: A Practical Guide.
    Advances in therapy, 2017, Volume: 34, Issue:3

    Topics: Age Factors; Anticoagulants; Atrial Fibrillation; Comparative Effectiveness Research; Humans; Medication Therapy Management; Practice Guidelines as Topic; Pyridines; Thiazoles; Venous Thromboembolism; Warfarin

2017
Anticoagulation Therapy and NOACs in Heart Failure.
    Handbook of experimental pharmacology, 2017, Volume: 243

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Clinical Trials as Topic; Dabigatran; Factor Xa Inhibitors; Heart Failure; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Venous Thromboembolism; Warfarin

2017
Laboratory Monitoring of Non-Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation: A Review.
    JAMA cardiology, 2017, 05-01, Volume: 2, Issue:5

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Chromatography, High Pressure Liquid; Dabigatran; Factor Xa Inhibitors; Hemorrhage; Humans; Intracranial Hemorrhages; Partial Thromboplastin Time; Prothrombin Time; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Tandem Mass Spectrometry; Thiazoles; Thrombin Time; Warfarin

2017
Direct Oral Anticoagulants for the Treatment of Venous Thromboembolism in Japan.
    Journal of atherosclerosis and thrombosis, 2017, Jun-01, Volume: 24, Issue:6

    Topics: Administration, Oral; Anticoagulants; Clinical Trials as Topic; Factor Xa Inhibitors; Hemorrhage; Hospitalization; Humans; Japan; Neoplasms; Outpatients; Platelet Count; Pyrazoles; Pyridines; Pyridones; Recurrence; Rivaroxaban; Thiazoles; Venous Thromboembolism; Warfarin

2017
Nonvitamin K-dependent oral anticoagulants (NOACs) in chronic kidney disease patients with atrial fibrillation.
    Thrombosis research, 2017, Volume: 155

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Prospective Studies; Pyrazoles; Pyridines; Pyridones; Renal Insufficiency, Chronic; Rivaroxaban; Stroke; Thiazoles; Thromboembolism; Warfarin

2017
Appropriateness of Oral Anticoagulants for the Long-Term Treatment of Atrial Fibrillation in Older People: Results of an Evidence-Based Review and International Consensus Validation Process (OAC-FORTA 2016).
    Drugs & aging, 2017, Volume: 34, Issue:7

    Topics: Administration, Oral; Age Factors; Aged; Anticoagulants; Atrial Fibrillation; Consensus; Dabigatran; Delphi Technique; Europe; Evidence-Based Practice; Female; Humans; Long-Term Care; Middle Aged; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Stroke; Thiazoles; Warfarin

2017
Renal Function Considerations for Stroke Prevention in Atrial Fibrillation.
    The American journal of medicine, 2017, Volume: 130, Issue:9

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Embolism; Factor Xa Inhibitors; Hemorrhage; Humans; Pharmaceutical Research; Pyrazoles; Pyridines; Pyridones; Renal Insufficiency; Risk Assessment; Rivaroxaban; Stroke; Therapeutic Equivalency; Thiazoles; Warfarin

2017
The Efficacy and Safety of 3 Types of Interventions for Stroke Prevention in Patients With Cardiovascular and Cerebrovascular Diseases: A Network Meta-analysis.
    Clinical therapeutics, 2017, Volume: 39, Issue:7

    Topics: Anticoagulants; Aspirin; Bayes Theorem; Cardiovascular Diseases; Clopidogrel; Dabigatran; Dipyridamole; Hemorrhage; Humans; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Thiazoles; Ticlopidine; Treatment Outcome; Warfarin

2017
Risk of major bleeding in patients with non-valvular atrial fibrillation treated with oral anticoagulants: a systematic review of real-world observational studies.
    Current medical research and opinion, 2017, Volume: 33, Issue:9

    Topics: Anticoagulants; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Risk; Rivaroxaban; Thiazoles; Warfarin

2017
Risk analysis of new oral anticoagulants for gastrointestinal bleeding and intracranial hemorrhage in atrial fibrillation patients: a systematic review and network meta-analysis.
    Journal of Zhejiang University. Science. B, 2017, Volume: 18, Issue:7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Bayes Theorem; Clinical Trials as Topic; Dabigatran; Female; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Markov Chains; Middle Aged; Monte Carlo Method; Network Meta-Analysis; Odds Ratio; Pyridines; Randomized Controlled Trials as Topic; Risk; Thiazoles; Warfarin

2017
Risk of Intraocular Bleeding With Novel Oral Anticoagulants Compared With Warfarin: A Systematic Review and Meta-analysis.
    JAMA ophthalmology, 2017, 08-01, Volume: 135, Issue:8

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Eye Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Risk Assessment; Rivaroxaban; Thiazoles; Venous Thromboembolism; Warfarin

2017
Comparative effectiveness of rivaroxaban in the treatment of nonvalvular atrial fibrillation.
    Journal of comparative effectiveness research, 2017, Volume: 6, Issue:6

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Drug Administration Schedule; Epidemiologic Methods; Factor Xa Inhibitors; Female; Humans; Male; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Warfarin

2017
Use of direct oral anticoagulants for stroke prevention in elderly patients with nonvalvular atrial fibrillation.
    Journal of the American Association of Nurse Practitioners, 2017, Volume: 29, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Dabigatran; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
Reversal agents for oral anticoagulants.
    The Nurse practitioner, 2017, Nov-16, Volume: 42, Issue:11

    Topics: Administration, Oral; Anticoagulants; Clinical Trials, Phase III as Topic; Dabigatran; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2017
Effects of different anticoagulant drugs on the prevention of complications in patients after arthroplasty: A network meta-analysis.
    Medicine, 2017, Volume: 96, Issue:40

    Topics: Anticoagulants; Arthroplasty; Azetidines; Benzylamines; Dabigatran; Enoxaparin; Heparin; Heparin, Low-Molecular-Weight; Humans; Network Meta-Analysis; Postoperative Complications; Pulmonary Embolism; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Treatment Outcome; Venous Thromboembolism; Warfarin

2017
Outcome of intracerebral haemorrhage related to non-vitamin K antagonists oral anticoagulants versus vitamin K antagonists: a comprehensive systematic review and meta-analysis.
    Journal of neurology, neurosurgery, and psychiatry, 2018, Volume: 89, Issue:3

    Topics: Anticoagulants; Antithrombins; Cerebral Hemorrhage; Dabigatran; Factor Xa Inhibitors; Hematoma; Humans; Mortality; Odds Ratio; Phenprocoumon; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Severity of Illness Index; Thiazoles; Vitamin K; Warfarin

2018
Direct oral anticoagulants versus warfarin for preventing stroke and systemic embolic events among atrial fibrillation patients with chronic kidney disease.
    The Cochrane database of systematic reviews, 2017, Nov-06, Volume: 11

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Embolism; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
Management of Anticoagulation in Patients With Prostate Cancer Receiving Enzalutamide.
    Journal of oncology practice, 2017, Volume: 13, Issue:11

    Topics: Androgen Receptor Antagonists; Anticoagulants; Atrial Fibrillation; Benzamides; Dabigatran; Drug Interactions; Embolism; Heart Valve Prosthesis; Heparin, Low-Molecular-Weight; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Venous Thromboembolism; Warfarin

2017
A systematic review of direct oral anticoagulant use in chronic kidney disease and dialysis patients with atrial fibrillation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019, 02-01, Volume: 34, Issue:2

    Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Dabigatran; Embolism; Glomerular Filtration Rate; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Renal Dialysis; Renal Insufficiency, Chronic; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Warfarin

2019
A review of the use of direct oral anticoagulant use in orthotopic heart transplantation recipients.
    Transplantation reviews (Orlando, Fla.), 2018, Volume: 32, Issue:3

    Topics: Administration, Oral; Anticoagulants; Dabigatran; Heart Transplantation; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2018
Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2019, 02-07, Volume: 14, Issue:2

    Topics: Administration, Oral; Anticoagulants; Antidotes; Antithrombins; Dabigatran; Factor Xa Inhibitors; Humans; International Normalized Ratio; Pyrazoles; Pyridines; Pyridones; Renal Insufficiency, Chronic; Rivaroxaban; Thiazoles; Warfarin

2019
The efficacy and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation and coronary artery disease: A meta-analysis of randomized trials.
    European heart journal. Acute cardiovascular care, 2019, Volume: 8, Issue:6

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Case-Control Studies; Clinical Trials, Phase III as Topic; Coronary Artery Disease; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Mortality; Myocardial Infarction; Pyridines; Randomized Controlled Trials as Topic; Safety; Stroke; Thiazoles; Treatment Outcome; Warfarin

2019
The safety of NOACs in atrial fibrillation patient subgroups: A narrative review.
    International journal of clinical practice, 2019, Volume: 73, Issue:2

    Topics: Administration, Oral; Age Factors; Anticoagulants; Atrial Fibrillation; Clinical Trials, Phase III as Topic; Dabigatran; Hemorrhage; Humans; Pyrazoles; Pyridines; Pyridones; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Warfarin

2019
[Improved stroke prevention in atrial fibrillation: the Stockholm experience of the introduction of NOACs].
    Lakartidningen, 2018, 10-26, Volume: 115

    Topics: Aged, 80 and over; Antithrombins; Atrial Fibrillation; Dabigatran; Humans; Ischemic Attack, Transient; Observational Studies as Topic; Pyrazoles; Pyridines; Pyridones; Risk Assessment; Rivaroxaban; Stroke; Sweden; Thiazoles; Warfarin

2018
Oral Anticoagulation in Patients With End-Stage Kidney Disease on Dialysis and Atrial Fibrillation.
    Seminars in nephrology, 2018, Volume: 38, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Dabigatran; Humans; Kidney Failure, Chronic; Pyrazoles; Pyridines; Pyridones; Renal Dialysis; Rivaroxaban; Thiazoles; Thromboembolism; Warfarin

2018
Efficacy and safety of reduced-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a meta-analysis of randomized controlled trials.
    European heart journal, 2019, 05-14, Volume: 40, Issue:19

    Topics: Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Embolism; Factor Xa Inhibitors; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Stroke; Thiazoles; Warfarin

2019
The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V-Special Situations.
    Thrombosis and haemostasis, 2019, Volume: 119, Issue:1

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Atrial Fibrillation; Benzamides; Biomarkers; Blood Coagulation; Clinical Trials as Topic; Dabigatran; Drug Administration Schedule; Factor Xa; Heart Diseases; Humans; Piperazines; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Risk; Rivaroxaban; Stroke; Thiazoles; Thrombin; Venous Thromboembolism; Vitamin K; Warfarin

2019
Edoxaban for the prevention of stroke in patients with atrial fibrillation.
    Expert review of cardiovascular therapy, 2019, Volume: 17, Issue:4

    Topics: Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Cost-Benefit Analysis; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Stroke; Thiazoles; Thromboembolism; Warfarin

2019
Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin in Patients With Cancer and Atrial Fibrillation: A Systematic Review and Meta-Analysis.
    Journal of the American Heart Association, 2019, 07-16, Volume: 8, Issue:14

    Topics: Anticoagulants; Atrial Fibrillation; Dabigatran; Embolism; Factor Xa Inhibitors; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Intracranial Hemorrhages; Neoplasms; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Venous Thromboembolism; Warfarin

2019
Comparative efficacy and safety of warfarin care bundles and novel oral anticoagulants in patients with atrial fibrillation: a systematic review and network meta-analysis.
    Scientific reports, 2020, 01-20, Volume: 10, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Hemorrhage; Humans; Male; Middle Aged; Patient Care Bundles; Pyridines; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Treatment Outcome; Warfarin

2020
    MMW Fortschritte der Medizin, 2020, Volume: 162, Issue:4

    Topics: Atrial Fibrillation; Blood Pressure; Humans; Hypertension; Pyridines; Thiazoles; Warfarin

2020
Non-Vitamin K Antagonist Oral Anticoagulants in Secondary Stroke Prevention in Atrial Fibrillation Patients: An Updated Analysis by Adding Observational Studies.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:4

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Factor Xa Inhibitors; Humans; Intracranial Hemorrhages; Observational Studies as Topic; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Risk Factors; Rivaroxaban; Secondary Prevention; Stroke; Thiazoles; Treatment Outcome; Vitamin K; Warfarin

2020
Anticoagulants for Stroke Prevention in Atrial Fibrillation in Elderly Patients.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:4

    Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Factor Xa Inhibitors; Female; Humans; Intracranial Hemorrhages; Male; Pyrazoles; Pyridines; Pyridones; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Vitamin K; Warfarin

2020
The role of non-vitamin K antagonist oral anticoagulants in Asian patients with atrial fibrillation: A PRISMA-compliant article.
    Medicine, 2020, Jul-02, Volume: 99, Issue:27

    Topics: Administration, Oral; Aged; Anticoagulants; Antithrombins; Asia; Asian People; Atrial Fibrillation; Cost of Illness; Dabigatran; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Network Meta-Analysis; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Safety; Stroke; Thiazoles; Warfarin

2020
[Direct Oral Anticoagulant Edoxaban in Patients with Non-Valvular Atrial Fibrillation: Results of Direct Comparison with Warfarin].
    Kardiologiia, 2020, Sep-17, Volume: 60, Issue:8

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Factor Xa Inhibitors; Humans; Prospective Studies; Pyridines; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Treatment Outcome; Warfarin

2020
Non-Vitamin K Antagonist Oral Anticoagulants Versus Warfarin for Patients With Left Ventricular Thrombus: A Systematic Review and Meta-Analysis.
    The American journal of cardiology, 2021, 03-01, Volume: 142

    Topics: Anticoagulants; Antithrombins; Dabigatran; Embolism; Factor Xa Inhibitors; Heart Diseases; Heart Ventricles; Hemorrhage; Humans; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thrombosis; Warfarin

2021
The efficacy and safety of edoxaban versus warfarin in preventing clinical events in atrial fibrillation: A systematic review and meta-analysis.
    Anatolian journal of cardiology, 2021, Volume: 25, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2021
The risk of gastrointestinal hemorrhage with non-vitamin K antagonist oral anticoagulants: A network meta-analysis.
    Medicine, 2021, Mar-19, Volume: 100, Issue:11

    Topics: Administration, Oral; Adult; Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Enoxaparin; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Network Meta-Analysis; Observational Studies as Topic; Pulmonary Embolism; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Venous Thromboembolism; Warfarin

2021
Monoamine oxidase inhibitors: A concise review with special emphasis on structure activity relationship studies.
    European journal of medicinal chemistry, 2022, Nov-15, Volume: 242

    Topics: Aldehydes; Ammonia; Caffeine; Chalcones; Chromones; Clorgyline; Coumarins; Hydrogen Peroxide; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Selegiline; Structure-Activity Relationship; Thiazoles; Thiourea

2022

Trials

74 trial(s) available for thiazoles and warfarin

ArticleYear
Effects of nitazoxanide on pharmacokinetics and pharmacodynamics of a single dose of warfarin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, May-01, Volume: 66, Issue:9

    Topics: Adolescent; Adult; Antiparasitic Agents; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles; Warfarin

2009
Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:3

    Topics: Administration, Oral; Aged; Alanine Transaminase; Anticoagulants; Aspartate Aminotransferases; Atrial Fibrillation; Bilirubin; Biomarkers; Blood Coagulation; Double-Blind Method; Europe, Eastern; Factor Xa; Factor Xa Inhibitors; Female; Fibrin Fibrinogen Degradation Products; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Time Factors; Treatment Outcome; United States; Warfarin

2010
Evaluation of the novel factor Xa inhibitor edoxaban compared with warfarin in patients with atrial fibrillation: design and rationale for the Effective aNticoaGulation with factor xA next GEneration in Atrial Fibrillation-Thrombolysis In Myocardial Infar
    American heart journal, 2010, Volume: 160, Issue:4

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Pyridines; Retrospective Studies; Stroke; Thiazoles; Thrombolytic Therapy; Treatment Outcome; Warfarin

2010
Safety of edoxaban, an oral factor Xa inhibitor, in Asian patients with non-valvular atrial fibrillation.
    Thrombosis and haemostasis, 2011, Volume: 105, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Asian People; Atrial Fibrillation; Double-Blind Method; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Middle Aged; Pyridines; Thiazoles; Warfarin

2011
Comparison of antithrombotic and haemorrhagic effects of edoxaban, an oral direct factor Xa inhibitor, with warfarin and enoxaparin in rats.
    Thrombosis research, 2012, Volume: 130, Issue:3

    Topics: Administration, Oral; Animals; Anticoagulants; Enoxaparin; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrhage; Hemostatics; Male; Pyridines; Rats; Rats, Wistar; Thiazoles; Treatment Outcome; Venous Thrombosis; Warfarin

2012
Randomized, multicenter, warfarin-controlled phase II study of edoxaban in Japanese patients with non-valvular atrial fibrillation.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:8

    Topics: Aged; Anticoagulants; Asian People; Atrial Fibrillation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemorrhage; Humans; Incidence; International Normalized Ratio; Japan; Male; Middle Aged; Pyridines; Thiazoles; Warfarin

2012
A randomized trial of the safety, pharmacokinetics and pharmacodynamics of edoxaban, an oral factor Xa inhibitor, following a switch from warfarin.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Anticoagulants; Blood Coagulation Tests; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyridines; Thiazoles; Warfarin

2013
Edoxaban for the long-term treatment of venous thromboembolism: rationale and design of the Hokusai-venous thromboembolism study--methodological implications for clinical trials.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:7

    Topics: Administration, Oral; Anticoagulants; Blood Coagulation; Blood Coagulation Tests; Clinical Protocols; Double-Blind Method; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Predictive Value of Tests; Pyridines; Research Design; Secondary Prevention; Thiazoles; Time Factors; Treatment Outcome; Venous Thromboembolism; Warfarin

2013
Edoxaban versus warfarin in patients with atrial fibrillation.
    The New England journal of medicine, 2013, Nov-28, Volume: 369, Issue:22

    Topics: Adult; Aged; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Double-Blind Method; Embolism; Female; Follow-Up Studies; Hemorrhage; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Warfarin

2013
[Hokusai-VTE: edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism].
    Revue medicale de Liege, 2013, Volume: 68, Issue:10

    Topics: Anticoagulants; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Hemorrhage; Heparin; Humans; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Venous Thromboembolism; Warfarin

2013
Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48.
    Stroke, 2014, Volume: 45, Issue:8

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2014
Transition of patients from blinded study drug to open-label anticoagulation: the ENGAGE AF-TIMI 48 trial.
    Journal of the American College of Cardiology, 2014, Aug-12, Volume: 64, Issue:6

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Drug Substitution; Factor Xa; Female; Humans; Male; Middle Aged; Myocardial Infarction; Pyridines; Thiazoles; Treatment Outcome; Warfarin

2014
Interactions of the hepatitis C virus protease inhibitor faldaprevir with cytochrome P450 enzymes: in vitro and in vivo correlation.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Aminoisobutyric Acids; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Healthy Volunteers; Hepatitis C; Humans; In Vitro Techniques; Isoenzymes; Leucine; Male; Microsomes, Liver; Midazolam; Middle Aged; Oligopeptides; Proline; Protease Inhibitors; Quinolines; Thiazoles; Warfarin; Young Adult

2015
Edoxaban vs. warfarin in vitamin K antagonist experienced and naive patients with atrial fibrillation†.
    European heart journal, 2015, Jun-14, Volume: 36, Issue:23

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyridines; Risk Factors; Stroke; Thiazoles; Treatment Outcome; Warfarin

2015
Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.
    Lancet (London, England), 2015, Jun-06, Volume: 385, Issue:9984

    Topics: Anticoagulants; Atrial Fibrillation; Cytochrome P-450 CYP2C9; Double-Blind Method; Factor Xa Inhibitors; Genetic Variation; Genotype; Hemorrhage; Humans; International Normalized Ratio; Pharmacogenetics; Pyridines; Risk Assessment; Stroke; Thiazoles; Vitamin K Epoxide Reductases; Warfarin

2015
A prospective evaluation of edoxaban compared to warfarin in subjects undergoing cardioversion of atrial fibrillation: The EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study.
    American heart journal, 2015, Volume: 169, Issue:5

    Topics: Adult; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Electric Countershock; Factor Xa Inhibitors; Female; Humans; Male; Prospective Studies; Pyridines; Research Design; Stroke; Thiazoles; Thromboembolism; Warfarin

2015
Edoxaban vs. warfarin in patients with atrial fibrillation on amiodarone: a subgroup analysis of the ENGAGE AF-TIMI 48 trial.
    European heart journal, 2015, Sep-01, Volume: 36, Issue:33

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2015
Efficacy and safety of edoxaban for treatment of venous thromboembolism: a subanalysis of East Asian patients in the Hokusai-VTE trial.
    Journal of thrombosis and haemostasis : JTH, 2015, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Asia, Eastern; Asian People; Double-Blind Method; Factor Xa Inhibitors; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Pulmonary Embolism; Pyridines; Recurrence; Therapeutic Equivalency; Thiazoles; Venous Thromboembolism; Venous Thrombosis; Vitamin K; Warfarin; Young Adult

2015
Systemic, noncerebral, arterial embolism in 21,105 patients with atrial fibrillation randomized to edoxaban or warfarin: results from the Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction
    American heart journal, 2015, Volume: 170, Issue:4

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Double-Blind Method; Embolism; Factor Xa; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Middle Aged; Myocardial Infarction; Pyridines; Retrospective Studies; Thiazoles; Thrombolytic Therapy; Treatment Outcome; Warfarin

2015
Cost-effectiveness of edoxaban vs warfarin in patients with atrial fibrillation based on results of the ENGAGE AF-TIMI 48 trial.
    American heart journal, 2015, Volume: 170, Issue:6

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Monitoring; Embolism; Female; Hemorrhage; Humans; Male; Middle Aged; Patient Selection; Pyridines; Risk Assessment; Stroke; Survival Analysis; Thiazoles; Treatment Outcome; Warfarin

2015
Edoxaban vs warfarin in patients with nonvalvular atrial fibrillation in the US Food and Drug Administration approval population: An analysis from the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardi
    American heart journal, 2016, Volume: 172

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Dose-Response Relationship, Drug; Double-Blind Method; Drug Approval; Factor Xa; Factor Xa Inhibitors; Female; Humans; Male; Myocardial Infarction; Pyridines; Stroke; Thiazoles; Thrombolytic Therapy; United States; United States Food and Drug Administration; Warfarin

2016
Edoxaban vs. Warfarin in East Asian Patients With Atrial Fibrillation　- An ENGAGE AF-TIMI 48 Subanalysis.
    Circulation journal : official journal of the Japanese Circulation Society, 2016, Volume: 80, Issue:4

    Topics: Aged; Aged, 80 and over; Asia, Eastern; Atrial Fibrillation; Double-Blind Method; Embolism; Hemorrhage; Humans; Pyridines; Stroke; Thiazoles; Warfarin

2016
Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 Trial.
    Journal of the American Heart Association, 2016, Feb-23, Volume: 5, Issue:2

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Drug Administration Schedule; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Risk Assessment; Risk Factors; Stroke; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2016
Mortality in Patients with Atrial Fibrillation Randomized to Edoxaban or Warfarin: Insights from the ENGAGE AF-TIMI 48 Trial.
    The American journal of medicine, 2016, Volume: 129, Issue:8

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cause of Death; Dose-Response Relationship, Drug; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Male; Pyridines; Thiazoles; Treatment Outcome; United States; Warfarin

2016
Clinical impact and course of major bleeding with edoxaban versus vitamin K antagonists.
    Thrombosis and haemostasis, 2016, 07-04, Volume: 116, Issue:1

    Topics: Administration, Oral; Anticoagulants; Double-Blind Method; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Risk Factors; Thiazoles; Venous Thromboembolism; Vitamin K; Warfarin

2016
Cardioversion of Atrial Fibrillation in ENGAGE AF-TIMI 48.
    Clinical cardiology, 2016, Volume: 39, Issue:6

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Atrial Flutter; Combined Modality Therapy; Double-Blind Method; Electric Countershock; Factor Xa Inhibitors; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Pyridines; Risk Factors; Stroke; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2016
Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study.
    The Lancet. Haematology, 2016, Volume: 3, Issue:5

    Topics: Adult; Aged; Anticoagulants; Comparative Effectiveness Research; Double-Blind Method; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pulmonary Embolism; Pyridines; Recurrence; Risk Assessment; Secondary Prevention; Thiazoles; Venous Thromboembolism; Ventricular Dysfunction, Right; Warfarin

2016
Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study.
    Vascular medicine (London, England), 2016, Volume: 21, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Anticoagulants; Blood Coagulation; Drug Therapy, Combination; Factor Xa Inhibitors; Feasibility Studies; Female; Heparin; Humans; International Normalized Ratio; Magnetic Resonance Angiography; Male; Middle Aged; Phlebography; Predictive Value of Tests; Pyridines; Thiazoles; Time Factors; Treatment Outcome; United States; Venous Thrombosis; Warfarin

2016
Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF-TIMI 48 Trial.
    Journal of the American Heart Association, 2016, 05-20, Volume: 5, Issue:5

    Topics: Age Factors; Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2016
Edoxaban Exposure-Response Analysis and Clinical Utility Index Assessment in Patients With Symptomatic Deep-Vein Thrombosis or Pulmonary Embolism.
    CPT: pharmacometrics & systems pharmacology, 2016, Volume: 5, Issue:4

    Topics: Aged; Double-Blind Method; Drug Dosage Calculations; Factor Xa Inhibitors; Female; Humans; Male; Pulmonary Embolism; Pyridines; Risk Assessment; Thiazoles; Venous Thrombosis; Warfarin

2016
Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48.
    European journal of heart failure, 2016, Volume: 18, Issue:9

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Factor Xa Inhibitors; Female; Heart Failure; Hemorrhage; Humans; Male; Middle Aged; Proportional Hazards Models; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2016
Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial.
    Circulation, 2016, Jul-05, Volume: 134, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Creatinine; Double-Blind Method; Factor Xa Inhibitors; Female; Follow-Up Studies; Hemorrhage; Humans; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Pyridines; Risk; Thiazoles; Thrombophilia; Warfarin

2016
Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).
    Stroke, 2016, Volume: 47, Issue:8

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Brain Ischemia; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyridines; Recurrence; Secondary Prevention; Stroke; Thiazoles; Treatment Outcome; Warfarin

2016
Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism. An analysis of the randomised, double-blind HOKUSAI VTE trial.
    Thrombosis and haemostasis, 2016, Sep-27, Volume: 116, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyridines; Thiazoles; Venous Thromboembolism; Warfarin

2016
Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study.
    The Lancet. Haematology, 2016, Volume: 3, Issue:9

    Topics: Adolescent; Adult; Aged; Anticoagulants; Double-Blind Method; Equivalence Trials as Topic; Europe; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Pulmonary Embolism; Pyridines; Recurrence; Survival Rate; Thiazoles; Venous Thromboembolism; Ventricular Dysfunction, Right; Warfarin; Young Adult

2016
Edoxaban versus enoxaparin-warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial.
    Lancet (London, England), 2016, Oct-22, Volume: 388, Issue:10055

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Electric Countershock; Enoxaparin; Factor Xa Inhibitors; Hemorrhage; Humans; Middle Aged; Prospective Studies; Pyridines; Stroke; Thiazoles; Thromboembolism; Warfarin

2016
Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis.
    Journal of the American College of Cardiology, 2016, 09-13, Volume: 68, Issue:11

    Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyridines; Risk Factors; Single-Blind Method; Stroke; Thiazoles; Warfarin

2016
A novel risk prediction score in atrial fibrillation for a net clinical outcome from the ENGAGE AF-TIMI 48 randomized clinical trial.
    European heart journal, 2017, Mar-21, Volume: 38, Issue:12

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Risk Assessment; Risk Factors; Stroke; Thiazoles; Treatment Outcome; Warfarin

2017
Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).
    Circulation. Arrhythmia and electrophysiology, 2017, Volume: 10, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Pyridines; Risk Factors; Stroke; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2017
Prediction of major and clinically relevant bleeding in patients with VTE treated with edoxaban or vitamin K antagonists.
    Thrombosis and haemostasis, 2017, 04-03, Volume: 117, Issue:4

    Topics: Aged; Anticoagulants; Blood Coagulation; Decision Support Techniques; Double-Blind Method; Factor Xa Inhibitors; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Predictive Value of Tests; Pyridines; Risk Assessment; Risk Factors; Thiazoles; Treatment Outcome; Venous Thromboembolism; Vitamin K; Warfarin

2017
Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves.
    Circulation, 2017, 03-28, Volume: 135, Issue:13

    Topics: Anticoagulants; Atrial Fibrillation; Bioprosthesis; Blood Coagulation; Factor Xa Inhibitors; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Hemorrhage; Humans; Pyridines; Risk Factors; Stroke; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2017
External validation of the VTE-BLEED score for predicting major bleeding in stable anticoagulated patients with venous thromboembolism.
    Thrombosis and haemostasis, 2017, 06-02, Volume: 117, Issue:6

    Topics: Aged; Anticoagulants; Disease Progression; Female; Hemorrhage; Humans; Male; Middle Aged; Odds Ratio; Predictive Value of Tests; Prognosis; Pyridines; Research Design; Risk; Surveys and Questionnaires; Thiazoles; Venous Thromboembolism; Warfarin

2017
Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial.
    Journal of the American College of Cardiology, 2017, Mar-21, Volume: 69, Issue:11

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Embolism; Female; Heart Valve Diseases; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Warfarin

2017
First experience with edoxaban and atrial fibrillation ablation - Insights from the ENGAGE AF-TIMI 48 trial.
    International journal of cardiology, 2017, Oct-01, Volume: 244

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Pyridines; Thiazoles; Thrombolytic Therapy; Warfarin

2017
Genetics and clinical response to warfarin and edoxaban in patients with venous thromboembolism.
    Heart (British Cardiac Society), 2017, Volume: 103, Issue:22

    Topics: Adult; Aged; Anticoagulants; Blood Coagulation; Cytochrome P-450 CYP2C9; Double-Blind Method; Drug Monitoring; Factor Xa Inhibitors; Female; Genetic Predisposition to Disease; Hemorrhage; Humans; Male; Middle Aged; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Pyridines; Risk Assessment; Risk Factors; Thiazoles; Time Factors; Treatment Outcome; Venous Thromboembolism; Vitamin K Epoxide Reductases; Warfarin

2017
Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF-TIMI 48 Trial.
    Journal of the American Heart Association, 2017, Aug-11, Volume: 6, Issue:8

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Embolism; Factor Xa Inhibitors; Female; Gastrointestinal Hemorrhage; Health Status; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Pyridines; Quality of Life; Risk Factors; Stroke; Surveys and Questionnaires; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2017
The relationship of renal function to outcome: A post hoc analysis from the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study.
    American heart journal, 2017, Volume: 193

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Creatinine; Dose-Response Relationship, Drug; Electric Countershock; Factor Xa Inhibitors; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Pyridines; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2017
Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study.
    Thrombosis and haemostasis, 2017, Volume: 117, Issue:12

    Topics: Adult; Aged; Ambulatory Care; Anticoagulants; Double-Blind Method; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Thiazoles; United States; Venous Thromboembolism; Warfarin

2017
Edoxaban for the management of elderly Japanese patients with atrial fibrillation ineligible for standard oral anticoagulant therapies: Rationale and design of the ELDERCARE-AF study.
    American heart journal, 2017, Volume: 194

    Topics: Administration, Oral; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Incidence; Japan; Male; Pyridines; Stroke; Survival Rate; Thiazoles; Treatment Outcome; Warfarin

2017
Clinical events after interruption of anticoagulation in patients with atrial fibrillation: An analysis from the ENGAGE AF-TIMI 48 trial.
    International journal of cardiology, 2018, 04-15, Volume: 257

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pyridines; Retrospective Studies; Risk Factors; Stroke; Thiazoles; Thromboembolism; Warfarin; Withholding Treatment

2018
Uninterrupted administration of edoxaban vs vitamin K antagonists in patients undergoing atrial fibrillation catheter ablation: Rationale and design of the ELIMINATE-AF study.
    Clinical cardiology, 2018, Volume: 41, Issue:4

    Topics: Anticoagulants; Atrial Fibrillation; Brain Ischemia; Catheter Ablation; Clinical Protocols; Drug Administration Schedule; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Magnetic Resonance Imaging; Male; Prospective Studies; Pyridines; Research Design; Risk Factors; Stroke; Thiazoles; Time Factors; Treatment Outcome; Vitamin K; Warfarin

2018
Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Cardiac Surgical Procedures; Double-Blind Method; Female; Hemorrhage; Humans; Male; Perioperative Care; Postoperative Complications; Pyridines; Stroke; Thiazoles; Treatment Outcome; United States; Warfarin

2018
Abnormal vaginal bleeding in women of reproductive age treated with edoxaban or warfarin for venous thromboembolism: a post hoc analysis of the Hokusai-VTE study.
    BJOG : an international journal of obstetrics and gynaecology, 2018, Volume: 125, Issue:12

    Topics: Adult; Anticoagulants; Double-Blind Method; Female; Humans; Middle Aged; Pyridines; Thiazoles; Treatment Outcome; Uterine Hemorrhage; Venous Thromboembolism; Warfarin

2018
Edoxaban therapy increases treatment satisfaction and reduces utilization of healthcare resources: an analysis from the EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of atrial fibrillation (ENSURE-AF) study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018, 12-01, Volume: 20, Issue:12

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cost Savings; Cost-Benefit Analysis; Drug Costs; Echocardiography, Transesophageal; Electric Countershock; Emergency Service, Hospital; Europe; Factor Xa Inhibitors; Female; Hemorrhage; Hospital Costs; Humans; Male; Middle Aged; Patient Readmission; Patient Satisfaction; Pyridines; Risk Factors; Thiazoles; Time Factors; Treatment Outcome; United States; Warfarin

2018
Edoxaban in atrial fibrillation patients with established coronary artery disease: Insights from ENGAGE AF-TIMI 48.
    European heart journal. Acute cardiovascular care, 2019, Volume: 8, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Coronary Angiography; Coronary Artery Disease; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Pyridines; Thiazoles; Thrombolytic Therapy; Treatment Outcome; Warfarin

2019
Multicenter, Open-Label, Randomized Controlled Trial of Warfarin and Edoxaban Tosilate Hydrate for the Treatment of Deep Vein Thrombosis in Persons with Severe Motor Intellectual Disabilities.
    The Kurume medical journal, 2018, Dec-21, Volume: 65, Issue:1

    Topics: Anticoagulants; Factor Xa Inhibitors; Hemorrhage; Humans; Intellectual Disability; Intelligence; Japan; Motor Activity; Motor Disorders; Multicenter Studies as Topic; Persons with Mental Disabilities; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Time Factors; Treatment Outcome; Venous Thrombosis; Warfarin

2018
Edoxaban Versus Warfarin in Latin American Patients With Atrial Fibrillation: The ENGAGE AF-TIMI 48 Trial.
    Journal of the American College of Cardiology, 2018, 09-25, Volume: 72, Issue:13

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Double-Blind Method; Embolism; Factor Xa Inhibitors; Female; Hospitalization; Humans; Intracranial Hemorrhages; Latin America; Male; Myocardial Infarction; Pyridines; Stroke; Thiazoles; Warfarin

2018
Edoxaban and implantable cardiac device interventions: insights from the ENGAGE AF-TIMI 48 trial.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2019, Feb-01, Volume: 21, Issue:2

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Cardiac Resynchronization Therapy Devices; Defibrillators, Implantable; Device Removal; Double-Blind Method; Drug Administration Schedule; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Pacemaker, Artificial; Prosthesis Implantation; Pyridines; Risk Assessment; Risk Factors; Stroke; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2019
Clinical outcomes, edoxaban concentration, and anti-factor Xa activity of Asian patients with atrial fibrillation compared with non-Asians in the ENGAGE AF-TIMI 48 trial.
    European heart journal, 2019, 05-14, Volume: 40, Issue:19

    Topics: Aged; American Indian or Alaska Native; Anticoagulants; Asian People; Atrial Fibrillation; Black People; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Middle Aged; Proportional Hazards Models; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin; White People

2019
Relationship between body mass index and outcomes in patients with atrial fibrillation treated with edoxaban or warfarin in the ENGAGE AF-TIMI 48 trial.
    European heart journal, 2019, 05-14, Volume: 40, Issue:19

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Body Mass Index; Comorbidity; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Obesity; Overweight; Proportional Hazards Models; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2019
Spontaneous conversion in patients with non-valvular atrial fibrillation planned for electrical cardioversion: A subanalysis of the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion Of Atrial Fibrillation (ENSURE-AF) trial.
    American heart journal, 2019, Volume: 209

    Topics: Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Electric Countershock; Factor Xa Inhibitors; Female; Follow-Up Studies; Heart Rate; Humans; Male; Middle Aged; Pyridines; Remission, Spontaneous; Retrospective Studies; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2019
Edoxaban Versus Warfarin Stratified by Average Blood Pressure in 19 679 Patients With Atrial Fibrillation and a History of Hypertension in the ENGAGE AF-TIMI 48 Trial.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:3

    Topics: Aged; Aged, 80 and over; Atrial Fibrillation; Comorbidity; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Logistic Models; Male; Patient Safety; Prognosis; Proportional Hazards Models; Pyridines; Risk Assessment; Severity of Illness Index; Stroke; Survival Analysis; Thiazoles; Treatment Outcome; Warfarin

2019
Determinants of left atrium thrombi in scheduled cardioversion: an ENSURE-AF study analysis.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2019, Nov-01, Volume: 21, Issue:11

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography, Transesophageal; Electric Countershock; Factor Xa Inhibitors; Female; Heart Atria; Heart Diseases; Humans; Male; Prospective Studies; Pyridines; Thiazoles; Thrombosis; Treatment Outcome; Warfarin

2019
Comparison of Events Across Bleeding Scales in the ENGAGE AF-TIMI 48 Trial.
    Circulation, 2019, 11-26, Volume: 140, Issue:22

    Topics: Aged; Atrial Fibrillation; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Middle Aged; Pyridines; Risk Factors; Thiazoles; Warfarin

2019
Edoxaban versus warfarin in vitamin K antagonist experienced and naïve patients from the edoxaban versus warfarin in subjects undergoing cardioversion of atrial fibrillation (ENSURE-AF) randomised trial.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2020, Volume: 109, Issue:8

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Electric Countershock; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Pyridines; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2020
Effect of concomitant antiplatelet agents on clinical outcomes in the edoxaban vs warfarin in subjects undergoing cardioversion of atrial fibrillation (ENSURE-AF) randomized trial.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2020, Volume: 109, Issue:11

    Topics: Aged; Atrial Fibrillation; Electric Countershock; Factor Xa Inhibitors; Female; Follow-Up Studies; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Thiazoles; Thromboembolism; Time Factors; Treatment Outcome; Warfarin

2020
Cardiovascular- and Bleeding-Related Hospitalization Rates With Edoxaban Versus Warfarin in Patients With Atrial Fibrillation Based on Results of the ENGAGE AF-TIMI 48 Trial.
    Circulation. Cardiovascular quality and outcomes, 2020, Volume: 13, Issue:11

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cardiovascular Diseases; Factor Xa Inhibitors; Female; Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Pyridines; Risk Assessment; Risk Factors; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2020
Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial.
    BMC medicine, 2020, 12-24, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Double-Blind Method; Drug Administration Schedule; Factor Xa Inhibitors; Female; Follow-Up Studies; Frailty; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Prognosis; Pyridines; Thiazoles; Treatment Outcome; Warfarin

2020
Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation with warfarin or edoxaban: An in-depth analysis from the ENGAGE AF-TIMI 48 randomized trial.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2021, Volume: 86

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Double-Blind Method; Factor Xa Inhibitors; Female; Humans; Intracranial Hemorrhages; Male; Middle Aged; Pyridines; Thiazoles; Warfarin

2021
Edoxaban Exposure in Patients With Atrial Fibrillation and Estimated Creatinine Clearance Exceeding 100 mL/min.
    Clinical pharmacology in drug development, 2022, Volume: 11, Issue:5

    Topics: Anticoagulants; Atrial Fibrillation; Creatinine; Double-Blind Method; Humans; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2022
Ischaemic and bleeding risk in atrial fibrillation with and without peripheral artery disease and efficacy and safety of full- and half-dose edoxaban vs. warfarin: insights from ENGAGE AF-TIMI 48.
    European heart journal. Cardiovascular pharmacotherapy, 2022, Sep-29, Volume: 8, Issue:7

    Topics: Anticoagulants; Atrial Fibrillation; Embolism; Factor Xa Inhibitors; Hemorrhage; Humans; Peripheral Arterial Disease; Pyridines; Stroke; Thiazoles; Warfarin

2022
Edoxaban versus Warfarin in high-risk patients with atrial fibrillation: A comprehensive analysis of high-risk subgroups.
    American heart journal, 2022, Volume: 247

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Body Weight; Factor Xa Inhibitors; Humans; Pyridines; Stroke; Thiazoles; Treatment Outcome; Warfarin

2022
Effect of 15-mg Edoxaban on Clinical Outcomes in 3 Age Strata in Older Patients With Atrial Fibrillation: A Prespecified Subanalysis of the ELDERCARE-AF Randomized Clinical Trial.
    JAMA cardiology, 2022, 06-01, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Pyridines; Stroke; Thiazoles; Warfarin

2022
Laboratory Test Predictors for Major Bleeding in Elderly (≥80 Years) Patients With Nonvalvular Atrial Fibrillation Treated With Edoxaban 15 mg: Sub-Analysis of the ELDERCARE-AF Trial.
    Journal of the American Heart Association, 2022, 09-06, Volume: 11, Issue:17

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Creatinine; Double-Blind Method; Factor Xa Inhibitors; Hemorrhage; Humans; Pyridines; Stroke; Thiazoles; Warfarin

2022

Other Studies

360 other study(ies) available for thiazoles and warfarin

ArticleYear
Lack of interaction between nizatidine and warfarin during chronic administration.
    Journal of clinical pharmacology, 1988, Volume: 28, Issue:12

    Topics: Adult; Blood Coagulation Factors; Drug Interactions; Histamine H2 Antagonists; Humans; Nizatidine; Prothrombin; Thiazoles; Warfarin

1988
125I fibrinogen and the prevention of venous thrombosis.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 107, Issue:5

    Topics: Adult; Amides; Anticoagulants; Fibrinogen; Hematoma; Hemorrhage; Heparin; Hip Joint; Humans; Iodine Radioisotopes; Joint Prosthesis; Leg; Phlebography; Physical Examination; Postoperative Complications; Radionuclide Imaging; Thiazines; Thiazoles; Thrombophlebitis; Ultrasonography; Warfarin

1973
Tissue culture techniques in the study of cell photobiology and phototoxicity.
    The Journal of investigative dermatology, 1970, Volume: 54, Issue:2

    Topics: Animals; Antimalarials; Carcinoma; Cell Line; Coloring Agents; Coumarins; Culture Media; Culture Techniques; Fibroblasts; Haplorhini; Humans; Kidney; Laryngeal Neoplasms; Light; Methods; Penicillins; Phenothiazines; Photosensitivity Disorders; Porphyrins; Rabbits; Sulfanilamides; Tetracycline; Thiazoles; Tolbutamide

1970
The action of six anthelmintics against Trichostrongylus axei in lambs.
    The Veterinary record, 1972, Jun-10, Volume: 90, Issue:24

    Topics: Animals; Anthelmintics; Benzimidazoles; Carbamates; Coumarins; Imidazoles; Phenothiazines; Pyridines; Pyrimidines; Sheep; Sheep Diseases; Thiazoles; Time Factors; Trichostrongyloidiasis

1972
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase.
    Journal of virology, 1993, Volume: 67, Issue:4

    Topics: Amino Acid Sequence; Antiviral Agents; Benzimidazoles; Coumarins; Drug Resistance, Microbial; HIV; HIV Reverse Transcriptase; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thymine

1993
Comparison of the toxicity of allyl alcohol, coumarin and menadione in precision-cut rat, guinea-pig, cynomolgus monkey and human liver slices.
    Archives of toxicology, 1996, Volume: 71, Issue:1-2

    Topics: 1-Propanol; Animals; Coloring Agents; Coumarins; Guinea Pigs; Humans; Liver; Macaca fascicularis; Male; Potassium; Propanols; Protein Biosynthesis; Rats; Tetrazolium Salts; Thiazoles; Toxicity Tests; Vitamin K

1996
Micromolar and submicromolar Ca2+ spikes regulating distinct cellular functions in pancreatic acinar cells.
    The EMBO journal, 1997, Jan-15, Volume: 16, Issue:2

    Topics: Acetylcholine; Animals; Benzothiazoles; Calcium; Coumarins; Exocytosis; Fluorescent Dyes; Fura-2; Image Processing, Computer-Assisted; Mice; Microscopy, Fluorescence; Pancreas; Photolysis; Thiazoles

1997
Lack of interaction between meloxicam and warfarin in healthy volunteers.
    European journal of clinical pharmacology, 1997, Volume: 51, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Humans; Male; Meloxicam; Protein Binding; Stereoisomerism; Thiazines; Thiazoles; Warfarin

1997
Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Sep-01, Volume: 17, Issue:17

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiazoles; Calcium; Cell Death; Coumarins; Dextrans; Excitatory Amino Acid Agonists; Fluorescent Dyes; Forecasting; Fura-2; Intracellular Membranes; Ions; Mice; N-Methylaspartate; Neurons; Neurotoxins; Osmolar Concentration; Thiazoles

1997
Inhibition of etoposide-induced apoptotic events by azide.
    Immunology letters, 1997, Volume: 59, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azides; Coumarins; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Jurkat Cells; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Ultraviolet Rays

1997
Possible troglitazone-warfarin interaction.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, May-15, Volume: 55, Issue:10

    Topics: Anticoagulants; Blood Coagulation; Chromans; Diabetes Mellitus; Drug Interactions; Humans; Hypoglycemic Agents; International Normalized Ratio; Male; Middle Aged; Thiazoles; Thiazolidinediones; Thromboembolism; Troglitazone; Warfarin

1998
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).
    Pharmacogenetics, 1998, Volume: 8, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Base Sequence; Cloning, Molecular; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Gene Deletion; Genomic Library; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Substrate Specificity; Thiazoles; Thiazolidines

1998
Kinetic control of multiple forms of Ca(2+) spikes by inositol trisphosphate in pancreatic acinar cells.
    The Journal of cell biology, 1999, Jul-26, Volume: 146, Issue:2

    Topics: Acetylcholine; Animals; Benzothiazoles; Buffers; Calcium; Calcium Signaling; Coumarins; Dose-Response Relationship, Drug; Fluorescent Dyes; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Microscopy, Confocal; Models, Biological; Pancreas; Photolysis; Thiazoles

1999
Zinc biosensing with multiphoton excitation using carbonic anhydrase and improved fluorophores.
    Journal of biomedical optics, 2000, Volume: 5, Issue:1

    Topics: Anisotropy; Benzothiazoles; Carbonic Anhydrases; Coumarins; Fluorescent Dyes; Humans; Oxazoles; Spectrometry, Fluorescence; Sulfonamides; Thiazoles; Zinc

2000
The reaction of digitoxin and digoxin with cyanoacetic acid hydrazide: synthesis of coumarin, thiazole, thiophene and pyridine derivatives with potential biological activities.
    Archives of pharmacal research, 2001, Volume: 24, Issue:5

    Topics: Coumarins; Digitoxin; Digoxin; Hydrazines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Pyridines; Thiazoles; Thiophenes

2001
Azole-linked coumarin dyes as fluorescence probes of domain-forming polymers.
    Journal of photochemistry and photobiology. B, Biology, 2001, Dec-01, Volume: 65, Issue:1

    Topics: Benzimidazoles; Benzothiazoles; Coumarins; Fluorescent Dyes; Indicators and Reagents; Molecular Structure; Polymers; Polymethacrylic Acids; Spectrometry, Fluorescence; Thiazoles

2001
Synthesis and evaluation of anticancer activity of some imidazothiazolyl, imidazobenzothiazolyl and dihydroimidazothiazolyl coumarins.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:5

    Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Coumarins; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Infrared; Thiazoles; Tumor Cells, Cultured

2002
Near-membrane iminocoumarin-based low affinity fluorescent Ca(2+) indicators.
    Cell calcium, 2002, Volume: 31, Issue:5

    Topics: Animals; Benzimidazoles; Benzopyrans; Binding Sites; Calcium; Cell Membrane; Coumarins; Drosophila melanogaster; Embryo, Nonmammalian; Fluorescent Dyes; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Lipids; Microscopy, Fluorescence; Spectrum Analysis; Thiazoles

2002
2-Amino-1,3-benzothiazole-ethyl coumarin-3-carboxylate (1/1).
    Acta crystallographica. Section C, Crystal structure communications, 2003, Volume: 59, Issue:Pt 10

    Topics: Benzothiazoles; Coumarins; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Thiazoles

2003
Identification of biochemical markers linked to neonicotinoid cross resistance in Bemisia tabaci (Hemiptera: Aleyrodidae).
    Archives of insect biochemistry and physiology, 2003, Volume: 54, Issue:4

    Topics: Animals; Biological Assay; Biomarkers; Carbon Radioisotopes; Carboxylic Ester Hydrolases; Coumarins; Cytochrome P-450 Enzyme System; Glutathione Transferase; Hemiptera; Imidazoles; Insecticide Resistance; Insecticides; Lethal Dose 50; Neonicotinoids; Nitro Compounds; Oxazines; Plants; Pyridines; Radioligand Assay; Receptors, Nicotinic; Thiamethoxam; Thiazoles; Tritium

2003
Heat shock protects PC12 cells against MPP+ toxicity.
    Brain research, 2003, Dec-12, Volume: 993, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Blotting, Western; Cell Death; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Fluorescent Dyes; Heat-Shock Proteins; Hot Temperature; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; MPTP Poisoning; Neoplasm Proteins; Oligopeptides; PC12 Cells; Rats; Shock; Tetrazolium Salts; Thiazoles

2003
A new method to detect cadmium uptake in protoplasts.
    Planta, 2004, Volume: 219, Issue:3

    Topics: Biological Transport, Active; Cadmium; Coumarins; Cytosol; Fluorescent Dyes; Ion Transport; Microscopy, Fluorescence; Protoplasts; Seedlings; Thiazoles; Triticum; Vacuoles

2004
Discovery of a novel class of reversible non-peptide caspase inhibitors via a structure-based approach.
    Journal of medicinal chemistry, 2005, Mar-10, Volume: 48, Issue:5

    Topics: Caspase 3; Caspase 7; Caspase 8; Caspase Inhibitors; Caspases; Computer Simulation; Coumarins; Dioxanes; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Structure-Activity Relationship; Thiazoles

2005
Scoparone from Artemisia capillaris inhibits the release of inflammatory mediators in RAW 264.7 cells upon stimulation cells by interferon-gamma Plus LPS.
    Archives of pharmacal research, 2005, Volume: 28, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Artemisia; Blotting, Western; Cell Line; Cell Survival; Coumarins; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Stimulation, Chemical; Tetrazolium Salts; Thiazoles

2005
Solvent effects on the absorption and fluorescence spectra of coumarins 6 and 7 molecules: determination of ground and excited state dipole moment.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2006, Volume: 65, Issue:3-4

    Topics: Coumarins; Fluorescence; Imidazoles; Molecular Structure; Solvents; Spectrometry, Fluorescence; Thiazoles

2006
Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Constitutive Androstane Receptor; Coumarins; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Liver; Male; Orchiectomy; Oximes; Phenobarbital; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sex Factors; Steroid Hydroxylases; Swine; Swine, Miniature; Thiazoles; Transcription Factors

2006
Selective reduction of peptide isothiazolidin-3-ones.
    Organic letters, 2006, Dec-07, Volume: 8, Issue:25

    Topics: Coumarins; Fluorescent Dyes; Magnetic Resonance Spectroscopy; Organophosphonates; Oxidation-Reduction; Peptides; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Sulfhydryl Compounds; Sulfur; Thiazoles

2006
Poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy.
    International journal of pharmaceutics, 2007, Sep-05, Volume: 342, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Coumarins; Drug Compounding; Fluorescent Dyes; Glioma; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pressure; Tetrazolium Salts; Thiazoles

2007
Coumarin derivatives protection against ROS production in cellular models of Abeta toxicities.
    Free radical research, 2007, Volume: 41, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Coumarins; Free Radicals; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Models, Chemical; Mutation; Oxidative Stress; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2007
An improved synthesis of 4-chlorocoumarin-3-sulfonyl chloride and its reactions with different bidentate nucleophiles to give pyrido[1',2':2,3]- and thiazino[3',2':2,3]-1,2,4-thiadiazino[6,5-c]benzopyran-6-one 7,7-dioxides.
    Molecules (Basel, Switzerland), 2007, Aug-22, Volume: 12, Issue:8

    Topics: Aminopyridines; Anti-HIV Agents; Antineoplastic Agents; Benzopyrans; Coumarins; Sulfones; Thiazoles

2007
In vitro evaluation of poly(caporlactone) grafted dextran (PGD) nanoparticles with cancer cell.
    Journal of materials science. Materials in medicine, 2008, Volume: 19, Issue:5

    Topics: Biocompatible Materials; Cell Line, Tumor; Cell Survival; Coumarins; Dextrans; Drug Delivery Systems; Fluorescent Dyes; Humans; Microscopy, Atomic Force; Microscopy, Confocal; Nanoparticles; Particle Size; Polyesters; Spectrophotometry; Stomach Neoplasms; Thiazoles

2008
Cell cycle arrest and differentiation induction by 5,7-dimethoxycoumarin in melanoma cell lines.
    International journal of oncology, 2008, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Coumarins; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Melanoma; Melanoma, Experimental; Mice; Tetrazolium Salts; Thiazoles; Trypan Blue

2008
Two new bis-coumarin glycosides from Daphne giraldii NITSCHE.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Carbohydrate Conformation; Cell Line, Tumor; Coumarins; Daphne; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glycosides; Humans; Hydrolysis; Macrophages; Magnetic Resonance Spectroscopy; Nitric Oxide Synthase; Plant Bark; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles

2008
In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition.
    Xenobiotica; the fate of foreign compounds in biological systems, 2008, Volume: 38, Issue:5

    Topics: Blood Proteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Febuxostat; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Male; Microsomes, Liver; Protein Binding; Thiazoles; Warfarin; Xanthine Oxidase

2008
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands.
    Biochemical pharmacology, 2008, Jul-15, Volume: 76, Issue:2

    Topics: Anastrozole; Aromatase Inhibitors; Biological Assay; Cell Line, Tumor; Coumarins; ERRalpha Estrogen-Related Receptor; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fulvestrant; Genes, Reporter; Genistein; Humans; Letrozole; Ligands; Luciferases; Nitriles; Receptors, Estrogen; Response Elements; Tamoxifen; Thiazoles; Transfection; Triazoles

2008
Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles

2009
In vitro/in vivo biorecognition of lectin-immobilized fluorescent nanospheres for human colorectal cancer cells.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Feb-20, Volume: 134, Issue:1

    Topics: Acetamides; Animals; Antigens, Tumor-Associated, Carbohydrate; Cell Line; Colorectal Neoplasms; Coumarins; Diagnostic Imaging; Fluorescent Dyes; Humans; Mice; Mice, Nude; Models, Animal; Nanospheres; Peanut Agglutinin; Polyvinyls; Thiazoles

2009
Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Feb-20, Volume: 134, Issue:1

    Topics: Animals; Brain; Cell Line; Cell Survival; Coumarins; Drug Delivery Systems; Endothelial Cells; Lactoferrin; Mice; Nanoparticles; Polyesters; Polyethylene Glycols; Thiazoles

2009
Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor.
    International journal of pharmaceutics, 2009, Apr-17, Volume: 371, Issue:1-2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles; Xenograft Model Antitumor Assays

2009
Design and evaluation of a liposomal delivery system targeting the posterior segment of the eye.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Jun-19, Volume: 136, Issue:3

    Topics: Animals; Cell Line; Cell Survival; Chickens; Conjunctiva; Cornea; Coumarins; Eye; Fluorescent Dyes; Humans; Liposomes; Male; Mice; Microscopy, Atomic Force; Microscopy, Fluorescence; Ophthalmic Solutions; Ovum; Particle Size; Phosphatidylcholines; Retina; Thiazoles

2009
Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel.
    Biomaterials, 2009, Volume: 30, Issue:19

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Bentonite; Cell Line; Coumarins; Docetaxel; Drug Carriers; Drug Delivery Systems; Drug Therapy; Humans; Lactic Acid; Male; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Taxoids; Thiazoles; Vitamin E

2009
Enhanced antiviral activity of Acyclovir loaded into beta-cyclodextrin-poly(4-acryloylmorpholine) conjugate nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Jul-20, Volume: 137, Issue:2

    Topics: Acrylamides; Acyclovir; Animals; Antiviral Agents; beta-Cyclodextrins; Cell Membrane Permeability; Cell Survival; Chlorocebus aethiops; Coumarins; Drug Carriers; Herpesvirus 1, Human; Morpholines; Nanoparticles; Particle Size; Polymers; Thiazoles; Vero Cells

2009
Comparison of urinary scents of two related mouse species, Mus spicilegus and Mus domesticus.
    Journal of chemical ecology, 2009, Volume: 35, Issue:5

    Topics: Animals; Coumarins; Gas Chromatography-Mass Spectrometry; Lactones; Male; Mice; Pheromones; Smell; Species Specificity; Thiazoles

2009
The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs.
    International journal of pharmaceutics, 2009, Jun-22, Volume: 375, Issue:1-2

    Topics: Caco-2 Cells; Chitosan; Coloring Agents; Coumarins; Cross-Linking Reagents; Cyclodextrins; Drug Carriers; Excipients; Fluorescence; Humans; Microscopy, Confocal; Nanoparticles; Particle Size; Polyphosphates; Solubility; Thiazoles

2009
Anti-inflammatory effect of coumarins isolated from Corydalis heterocarpa in HT-29 human colon carcinoma cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Survival; Coloring Agents; Corydalis; Coumarins; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Furocoumarins; HT29 Cells; Humans; Inflammation Mediators; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles

2009
Organic dye lasers with distributed Bragg reflector grating and distributed feedback resonator.
    Optics express, 2009, Nov-23, Volume: 17, Issue:24

    Topics: Coloring Agents; Coumarins; Equipment Design; Lasers; Light; Materials Testing; Optics and Photonics; Organometallic Compounds; Oscillometry; Polymers; Polystyrenes; Polyvinyls; Surface Properties; Thiazoles

2009
Physicochemical properties affecting retinal drug/coumarin-6 delivery from nanocarrier systems via eyedrop administration.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Animals; Coumarins; Drug Delivery Systems; Emulsions; Liposomes; Macaca fascicularis; Male; Mice; Microscopy, Fluorescence; Ophthalmic Solutions; Particle Size; Rabbits; Retina; Thiazoles

2010
Interactions of human serum albumin with meloxicam: characterization of binding site.
    Journal of pharmaceutical and biomedical analysis, 2010, Jun-05, Volume: 52, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bilirubin; Binding Sites; Circular Dichroism; Humans; Hydrogen-Ion Concentration; Ligands; Meloxicam; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence; Thiazines; Thiazoles; Warfarin; Water

2010
In vitro and in vivo investigation of glucose-mediated brain-targeting liposomes.
    Journal of drug targeting, 2010, Volume: 18, Issue:7

    Topics: Animals; Area Under Curve; Astrocytes; Blood-Brain Barrier; Brain; Cholesterol; Coumarins; Drug Delivery Systems; Endothelial Cells; Glucose Transport Proteins, Facilitative; Liposomes; Mice; Rats; Rats, Sprague-Dawley; Thiazoles; Tissue Distribution

2010
Risk factors of drug interaction between warfarin and nonsteroidal anti-inflammatory drugs in practical setting.
    Journal of Korean medical science, 2010, Volume: 25, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Meloxicam; Middle Aged; Retrospective Studies; Risk Factors; Thiazines; Thiazoles; Warfarin

2010
Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, May-12, Volume: 40, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Coumarins; Dose-Response Relationship, Drug; Drug Carriers; Endothelial Cells; Lactoferrin; Liposomes; Mice; Molecular Structure; Rats; Thiazoles

2010
The differential spatial distribution of secondary metabolites in Arabidopsis leaves reacting hypersensitively to Pseudomonas syringae pv. tomato is dependent on the oxidative burst.
    Journal of experimental botany, 2010, Volume: 61, Issue:12

    Topics: Arabidopsis; Coumarins; Gene Expression Regulation, Plant; Glucosides; Indoles; Metabolome; Plant Diseases; Plant Leaves; Pseudomonas syringae; Reactive Oxygen Species; Respiratory Burst; Salicylic Acid; Signal Transduction; Thiazoles

2010
A novel lipoprotein-mimic nanocarrier composed of the modified protein and lipid for tumor cell targeting delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Sep-15, Volume: 146, Issue:3

    Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Coumarins; Drug Carriers; Humans; Lipids; Nanoparticles; Particle Size; Serum Albumin, Bovine; Thiazoles; Ursodeoxycholic Acid

2010
Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:4

    Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Chitosan; Coumarins; Drug Carriers; Female; Flow Cytometry; Fluorescence; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Surface Properties; Technology, Pharmaceutical; Thiazoles; Tissue Distribution

2010
Transferrin-conjugated nanoparticles of poly(lactide)-D-alpha-tocopheryl polyethylene glycol succinate diblock copolymer for targeted drug delivery across the blood-brain barrier.
    Biomaterials, 2010, Volume: 31, Issue:30

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Blood-Brain Barrier; Brain; Coumarins; Docetaxel; Drug Carriers; Drug Delivery Systems; Humans; Male; Materials Testing; Nanoparticles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Succinates; Taxoids; Thiazoles; Tissue Distribution; Transferrin

2010
Poly(vinyl benzoate) nanoparticles for molecular delivery: Studies on their preparation and in vitro properties.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Dec-01, Volume: 148, Issue:2

    Topics: Animals; Cattle; Cell Line; Cell Survival; Chemical Precipitation; Chemistry, Pharmaceutical; Coumarins; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Endothelial Cells; Escherichia coli K12; Fluoresceins; Fluorescent Dyes; Humans; Hydrolysis; Inhibitory Concentration 50; Keratinocytes; Kinetics; Microbial Sensitivity Tests; Nanoparticles; Nanotechnology; Particle Size; Poloxamer; Polyvinyls; Solubility; Staphylococcus aureus; Surface-Active Agents; Technology, Pharmaceutical; Thiazoles

2010
Novel 'nano in nano' composites for sustained drug delivery: biodegradable nanoparticles encapsulated into nanofiber non-wovens.
    Macromolecular bioscience, 2010, Dec-08, Volume: 10, Issue:12

    Topics: Coloring Agents; Coumarins; Drug Delivery Systems; Electric Conductivity; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanocomposites; Nanofibers; Nanoparticles; Nanotechnology; Particle Size; Polyglactin 910; Solubility; Spectrometry, Fluorescence; Surface Tension; Thiazoles

2010
Penetration and distribution of PLGA nanoparticles in the human skin treated with microneedles.
    International journal of pharmaceutics, 2010, Dec-15, Volume: 402, Issue:1-2

    Topics: Administration, Cutaneous; Chromatography, High Pressure Liquid; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Confocal; Nanoparticles; Needles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Skin Absorption; Thiazoles

2010
Novel synthesis of hydrazide-hydrazone derivatives and their utilization in the synthesis of coumarin, pyridine, thiazole and thiophene derivatives with antitumor activity.
    Molecules (Basel, Switzerland), 2010, Dec-23, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Azides; Cell Division; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; Humans; Hydrazones; Magnetic Resonance Spectroscopy; Pyridines; Thiazoles; Thiophenes

2010
A potential of peanut agglutinin-immobilized fluorescent nanospheres as a safe candidate of diagnostic drugs for colonoscopy.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Mar-18, Volume: 42, Issue:4

    Topics: Animals; Caco-2 Cells; Colon; Colonoscopy; Colorectal Neoplasms; Coumarins; Early Detection of Cancer; Female; Fluorescent Dyes; Humans; Indicators and Reagents; Intestinal Mucosa; Mice; Nanospheres; Peanut Agglutinin; Thiazoles

2011
Effects of surface modification on delivery efficiency of biodegradable nanoparticles across the blood-brain barrier.
    Nanomedicine (London, England), 2011, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Cell Line; Cell Line, Tumor; Coumarins; Docetaxel; Dogs; Drug Carriers; Humans; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Taxoids; Thiazoles

2011
Coumarin 6 and 1,6-diphenyl-1,3,5-hexatriene (DPH) as fluorescent probes to monitor protein aggregation.
    The Analyst, 2011, May-21, Volume: 136, Issue:10

    Topics: alpha-Synuclein; Benzothiazoles; Carbonic Anhydrases; Coumarins; Diphenylhexatriene; Fluorescent Dyes; Proteins; Quantum Theory; Spectrometry, Fluorescence; Thiazoles

2011
Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticles.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2011, Volume: 62, Issue:1

    Topics: Animals; Calorimetry, Differential Scanning; Cell Membrane; Chlorocebus aethiops; COS Cells; Coumarins; Drug Carriers; Epithelial Cells; Fatty Acids; HEK293 Cells; Humans; Lipids; Materials Testing; Nanoparticles; Pulmonary Alveoli; Temperature; Thiazoles; Transport Vesicles; Triglycerides

2011
Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway.
    Neuroscience, 2011, Jun-02, Volume: 183

    Topics: Animals; Animals, Newborn; Apoptosis; Cells, Cultured; Cerebral Cortex; Coumarins; Drug Interactions; Enzyme Inhibitors; Glucose; Hypoxia; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Neurons; Neuroprotective Agents; Rats; Reperfusion; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors

2011
Delivery of polymeric particles into skin using needle-free liquid jet injectors.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Aug-10, Volume: 153, Issue:3

    Topics: Coumarins; Drug Delivery Systems; Humans; In Vitro Techniques; Injections, Jet; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Skin; Solubility; Surface Properties; Thiazoles

2011
Folate-conjugated amphiphilic star-shaped block copolymers as targeted nanocarriers.
    Journal of biomedical materials research. Part A, 2011, Jun-15, Volume: 97, Issue:4

    Topics: Coumarins; Drug Carriers; Fluorescence; Folic Acid; HeLa Cells; Humans; Indomethacin; Magnetic Resonance Spectroscopy; Micelles; Molecular Weight; Nanostructures; Particle Size; Polyesters; Polyethylene Glycols; Propylene Glycols; Surface-Active Agents; Thiazoles

2011
Ferrociphenol lipid nanocapsule delivery by mesenchymal stromal cells in brain tumor therapy.
    International journal of pharmaceutics, 2012, Feb-14, Volume: 423, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coculture Techniques; Coumarins; Drug Delivery Systems; Female; Ferrous Compounds; Glioblastoma; Humans; Injections, Intralesional; Lipids; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Nude; Nanocapsules; Particle Size; Plant Lectins; Polyethylene Glycols; Soybean Proteins; Static Electricity; Stearic Acids; Thiazoles; Treatment Outcome; Triglycerides; Xenograft Model Antitumor Assays

2012
High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

    Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coated Materials, Biocompatible; Coumarins; Delayed-Action Preparations; Drug Carriers; Fluoresceins; Fluorescent Dyes; High-Throughput Screening Assays; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy; Microscopy, Electron, Scanning; Molecular Structure; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Solubility; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Surface Properties; Technology, Pharmaceutical; Thiazoles

2011
Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery.
    ACS nano, 2011, Jun-28, Volume: 5, Issue:6

    Topics: Animals; Axons; Coumarins; Drug Delivery Systems; ErbB Receptors; Female; Lactic Acid; Microscopy, Fluorescence; Microspheres; Models, Chemical; Nanospheres; Nerve Regeneration; Neurons; Optic Nerve; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrphostins

2011
Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers.
    Journal of drug targeting, 2011, Volume: 19, Issue:9

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Neoplasms; Cell Death; Cell Line, Tumor; Coumarins; Delayed-Action Preparations; Drug Delivery Systems; Glioma; Glutathione; Humans; Male; Mice; Mice, Inbred C57BL; Microtubules; Nanoparticles; Paclitaxel; Particle Size; Permeability; Rats; Thiazoles; Tubulin

2011
Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Anti-Infective Agents; Candida albicans; Coumarins; Crystallography, X-Ray; Gram-Negative Bacteria; Gram-Positive Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Spectrophotometry, Infrared; Thiazoles

2011
Preparation and in vitro properties of redox-responsive polymeric nanoparticles for paclitaxel delivery.
    Colloids and surfaces. B, Biointerfaces, 2011, Oct-15, Volume: 87, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Coumarins; Desiccation; Drug Carriers; Emulsions; Fluorescent Dyes; Glutathione; Humans; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Oxidation-Reduction; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Thiazoles

2011
A biophysical model of intracellular distribution and perinuclear accumulation of particulate matter.
    Biophysical chemistry, 2011, Volume: 158, Issue:2-3

    Topics: Cell Line; Cell Membrane Permeability; Coumarins; Cytoplasm; Cytoskeleton; Diffusion; Humans; Models, Biological; Nanoparticles; Particulate Matter; Pulmonary Alveoli; Temperature; Thiazoles

2011
A novel fluorescent probe for more effective monitoring of nanosized drug delivery systems within the cells.
    International journal of pharmaceutics, 2011, Sep-15, Volume: 416, Issue:1

    Topics: Cell Cycle; Cell Line; Cell Survival; Coumarins; Drug Carriers; Drug Compounding; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Nanoparticles; Particle Size; Surface Properties; Thiazoles

2011
In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Dec-10, Volume: 156, Issue:2

    Topics: Administration, Intravaginal; Animals; Avidin; Coumarins; Drug Carriers; Female; Mice; Mice, Inbred C57BL; Nanoparticles; Polyethylene Glycols; Polyglactin 910; Thiazoles; Vagina

2011
N-trimethyl chitosan-modified liposomes as carriers for oral delivery of salmon calcitonin.
    Drug delivery, 2011, Volume: 18, Issue:8

    Topics: Administration, Oral; Animals; Blood; Bone Density Conservation Agents; Calcitonin; Calcium; Chitosan; Cholesterol; Coumarins; Drug Carriers; Hydrogen-Ion Concentration; Intestine, Small; Magnetic Resonance Spectroscopy; Male; Microscopy, Atomic Force; Mucins; Organophosphates; Particle Size; Phosphatidylcholines; Rats; Rats, Wistar; Static Electricity; Surface Properties; Thiazoles; Unilamellar Liposomes

2011
Synthesis and free radical scavenging activity of coumarin derivatives containing a 2-methylbenzothiazoline motif.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:9

    Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Coumarins; Free Radical Scavengers; Free Radicals; Picrates; Structure-Activity Relationship; Sulfonic Acids; Thiazoles

2011
Self-aggregated pegylated poly (trimethylene carbonate) nanoparticles decorated with c(RGDyK) peptide for targeted paclitaxel delivery to integrin-rich tumors.
    Biomaterials, 2011, Volume: 32, Issue:35

    Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Coumarins; Dioxanes; Drug Delivery Systems; Humans; Integrins; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Peptides; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Subcellular Fractions; Thiazoles

2011
Low molecular weight protamine-functionalized nanoparticles for drug delivery to the brain after intranasal administration.
    Biomaterials, 2011, Volume: 32, Issue:36

    Topics: Administration, Intranasal; Animals; Brain; Cell Death; Cell Line; Coumarins; Drug Delivery Systems; Humans; Male; Molecular Weight; Nanoparticles; Photoelectron Spectroscopy; Protamines; Rats; Rats, Sprague-Dawley; Thiazoles; Tissue Distribution

2011
Synthesis and antioxidant activities of novel 4-Schiff base-7-benzyloxy-coumarin derivatives.
    Bioorganic & medicinal chemistry letters, 2011, Nov-15, Volume: 21, Issue:22

    Topics: Benzothiazoles; Biphenyl Compounds; Coumarins; Free Radical Scavengers; Free Radicals; Picrates; Schiff Bases; Sulfonic Acids; Superoxides; Thiazoles

2011
Self-assembled polymersomes conjugated with lactoferrin as novel drug carrier for brain delivery.
    Pharmaceutical research, 2012, Volume: 29, Issue:1

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Caspase 3; Coumarins; Cryoelectron Microscopy; Drug Carriers; Lactic Acid; Lactoferrin; Liposomes; Male; Mice; Mice, Inbred BALB C; Particle Size; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Thiazoles; Tissue Distribution

2012
Solanum tuberosum lectin-conjugated PLGA nanoparticles for nose-to-brain delivery: in vivo and in vitro evaluations.
    Journal of drug targeting, 2012, Volume: 20, Issue:2

    Topics: Administration, Intranasal; Animals; Anura; Brain; Cell Line, Tumor; Cell Survival; Chitin; Cilia; Coumarins; Drug Delivery Systems; Endocytosis; Humans; Imidazoles; Lactic Acid; Male; Nanoparticles; Particle Size; Plant Lectins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Thiazoles

2012
Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells.
    International journal of pharmaceutics, 2011, Dec-15, Volume: 421, Issue:2

    Topics: Absorption; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Docetaxel; Glioma; Humans; Liposomes; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Transmission; Particle Size; Polyethylene Glycols; Taxoids; Thiazoles; Vitamin E

2011
A novel small Odorranalectin-bearing cubosomes: preparation, brain delivery and pharmacodynamic study on amyloid-β₂₅₋₃₅-treated rats following intranasal administration.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 80, Issue:2

    Topics: Administration, Intranasal; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Coumarins; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glycine; Intracellular Signaling Peptides and Proteins; Lectins; Maze Learning; Peptide Fragments; Rats; Rats, Sprague-Dawley; Streptavidin; Thiazoles; Tissue Distribution

2012
Novel docetaxel-loaded nanoparticles based on PCL-Tween 80 copolymer for cancer treatment.
    International journal of nanomedicine, 2011, Volume: 6

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coumarins; Docetaxel; Nanocapsules; Particle Size; Polyesters; Polysorbates; Rats; Surface Properties; Taxoids; Thiazoles

2011
Enhanced transdermal delivery of indomethacin using combination of PLGA nanoparticles and iontophoresis in vivo.
    Colloids and surfaces. B, Biointerfaces, 2012, Apr-01, Volume: 92

    Topics: Administration, Cutaneous; Animals; Coumarins; Drug Delivery Systems; Indomethacin; Iontophoresis; Lactic Acid; Microscopy, Confocal; Nanoparticles; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Thiazoles

2012
Nose-to-brain transport pathways of wheat germ agglutinin conjugated PEG-PLA nanoparticles.
    Pharmaceutical research, 2012, Volume: 29, Issue:2

    Topics: Administration, Intranasal; Animals; Biological Transport; Brain; Coumarins; Nanoparticles; Nasal Mucosa; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Thiazoles; Wheat Germ Agglutinins

2012
Monitoring the transport of polymeric micelles across MDCK cell monolayer and exploring related mechanisms.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Mar-28, Volume: 158, Issue:3

    Topics: Animals; Cell Line; Cell Membrane; Chelating Agents; Coumarins; Dogs; Egtazic Acid; Endocytosis; Epithelial Cells; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kidney; Micelles; Microscopy, Confocal; Microscopy, Electron, Transmission; Polyethylene Glycols; Thiazoles

2012
Synthesis, reactions and antimicrobial activities of 8-ethoxycoumarin derivatives.
    Molecules (Basel, Switzerland), 2012, Jan-18, Volume: 17, Issue:1

    Topics: Anti-Bacterial Agents; Coumarins; Cyclization; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrazones; Microbial Sensitivity Tests; Nitriles; Thiazoles; Thiocyanates; Transition Temperature

2012
Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Coumarins; Drug Delivery Systems; Drug Stability; Glucose; Liposomes; Mice; Polyethylene Glycols; Spectroscopy, Near-Infrared; Thiazoles; Tissue Distribution

2012
Hepatocellular carcinoma targeting effect of PEGylated liposomes modified with lactoferrin.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jun-14, Volume: 46, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Chemistry, Pharmaceutical; Coumarins; Hep G2 Cells; Humans; Lactoferrin; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Polyethylene Glycols; Random Allocation; Thiazoles; Xenograft Model Antitumor Assays

2012
A novel and facile approach to imaging nanoparticles transport across Transwell filter grown cell monolayer in real-time and in situ under confocal laser scanning microscopy.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:3

    Topics: Animals; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Coumarins; Dogs; Endocytosis; Fluorescent Dyes; Melanoma, Experimental; Mice; Microscopy, Confocal; Nanoparticles; Thiazoles

2012
Stimulus-responsive supramolecular pKa tuning of cucurbit[7]uril encapsulated coumarin 6 dye.
    The journal of physical chemistry. B, 2012, Mar-29, Volume: 116, Issue:12

    Topics: Bridged-Ring Compounds; Coumarins; Hydrogen-Ion Concentration; Imidazoles; Ions; Kinetics; Metals; Protons; Temperature; Thiazoles

2012
Preparation of a cationic nanoemulsome for intratumoral drug delivery and its enhancing effect on cellular uptake in vitro.
    Journal of nanoscience and nanotechnology, 2011, Volume: 11, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cations; Caveolae; Cell Line, Tumor; Cells, Cultured; Cetrimonium; Cetrimonium Compounds; CHO Cells; Clathrin; Coumarins; Cricetinae; Drug Carriers; Drug Delivery Systems; Emulsions; Female; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Nanoparticles; Particle Size; Pinocytosis; Polymers; Solvents; Thiazoles

2011
Inhibition of aggregation of amyloid β42 by arginine-containing small compounds.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:4

    Topics: Amyloid; Amyloid beta-Peptides; Arginine; Benzothiazoles; Coumarins; Dipeptides; Electrophoresis, Polyacrylamide Gel; Humans; Peptide Fragments; Polymerization; Protein Binding; Small Molecule Libraries; Solubility; Solutions; Thiazoles

2012
Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Oct-10, Volume: 163, Issue:1

    Topics: Acoustics; Animals; Cell Line, Tumor; Coumarins; Cyanoacrylates; Drug Delivery Systems; Enbucrilate; Fluorescent Dyes; Mice; Microbubbles; Microscopy, Fluorescence; Neoplasms; Rhodamines; Thiazoles; Vascular Endothelial Growth Factor Receptor-2

2012
Synthesis and biological evaluation of 3-thiazolocoumarinyl Schiff-base derivatives as cholinesterase inhibitors.
    Chemical biology & drug design, 2012, Volume: 80, Issue:4

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Coumarins; Electrophorus; Horses; Molecular Docking Simulation; Schiff Bases; Thiazoles

2012
Edoxaban in Japanese patients with nonvalvular atrial fibrillation: not the same dose for everybody.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:8

    Topics: Anticoagulants; Atrial Fibrillation; Female; Humans; Male; Pyridines; Thiazoles; Warfarin

2012
A tissue factor targeted nanomedical system for thrombi-specific drug delivery.
    Biomaterials, 2012, Volume: 33, Issue:30

    Topics: Animals; Blood Coagulation; Brain; Cell Death; Cells, Cultured; Coumarins; Drug Delivery Systems; Endothelial Cells; Factor VII; Green Fluorescent Proteins; Injections, Intravenous; Nanomedicine; Nanoparticles; Particle Size; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Static Electricity; Thiazoles; Thromboplastin; Thrombosis; Tumor Necrosis Factor-alpha

2012
Penetratin-functionalized PEG-PLA nanoparticles for brain drug delivery.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Animals; Brain; Carrier Proteins; Cell Survival; Cell-Penetrating Peptides; Coumarins; Dogs; Drug Carriers; Fluorescent Dyes; Madin Darby Canine Kidney Cells; Male; Mice; Mice, Inbred ICR; Mice, Nude; Nanoparticles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Thiazoles

2012
Preparation and characterization of teniposide PLGA nanoparticles and their uptake in human glioblastoma U87MG cells.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Acetone; Antineoplastic Agents; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Coumarins; Drug Carriers; Endocytosis; Fluorescent Dyes; Glioblastoma; Humans; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Teniposide; Thiazoles

2012
A physical model for the size-dependent cellular uptake of nanoparticles modified with cationic surfactants.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Caco-2 Cells; Cations; Coumarins; Emulsions; HT29 Cells; Humans; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quaternary Ammonium Compounds; Structure-Activity Relationship; Surface-Active Agents; Thiazoles

2012
A convenient ultrasound-promoted synthesis of some new thiazole derivatives bearing a coumarin nucleus and their cytotoxic activity.
    Molecules (Basel, Switzerland), 2012, Aug-03, Volume: 17, Issue:8

    Topics: Acetone; Acetophenones; Cell Line; Cell Survival; Coumarins; Dioxanes; Green Chemistry Technology; Humans; Hydrazones; Keratinocytes; Semicarbazides; Solvents; Sound; Thiazoles

2012
Synthesis, growth and vibrational spectroscopic study of a novel coumarinoylthiazole.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97

    Topics: Coumarins; Crystallization; Crystallography, X-Ray; Hydrogen Bonding; Molecular Conformation; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thiazoles; Vibration

2012
The effects of warfarin and edoxaban, an oral direct factor Xa inhibitor, on gammacarboxylated (Gla-osteocalcin) and undercarboxylated osteocalcin (uc-osteocalcin) in rats.
    Thrombosis research, 2013, Volume: 131, Issue:1

    Topics: Administration, Oral; Animals; Anticoagulants; Blood Coagulation; Carboxylic Acids; Enzyme-Linked Immunosorbent Assay; Factor Xa; Factor Xa Inhibitors; Male; Osteocalcin; Osteoporosis; Protein Processing, Post-Translational; Prothrombin Time; Pyridines; Rats; Rats, Wistar; Risk Factors; Thiazoles; Time Factors; Vitamin K; Warfarin

2013
Multifunctional nanobeacon for imaging Thomsen-Friedenreich antigen-associated colorectal cancer.
    International journal of cancer, 2013, May-01, Volume: 132, Issue:9

    Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Blotting, Western; Case-Control Studies; Colon; Colorectal Neoplasms; Coumarins; Diagnostic Imaging; Fluorescent Dyes; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Transgenic; Nanospheres; Peanut Agglutinin; Polystyrenes; Real-Time Polymerase Chain Reaction; Rectum; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Surface Properties; Thiazoles; Tissue Distribution; Tumor Cells, Cultured

2013
Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery.
    Biomaterials, 2013, Volume: 34, Issue:3

    Topics: Administration, Oral; Animals; Coumarins; Drug Delivery Systems; Endocytosis; Humans; Intestinal Mucosa; Intestines; Lactones; Male; Nanostructures; Peptides; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Thiazoles

2013
[Introduction].
    Revista clinica espanola, 2012, Volume: 212 Suppl 1

    Topics: Acenocoumarol; Anticoagulants; Benzamides; Benzimidazoles; beta-Alanine; Dabigatran; Heparin; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Thromboembolism; Thrombosis; Warfarin

2012
Distribution and deposition of respirable PLGA microspheres in lung alveoli.
    Colloids and surfaces. B, Biointerfaces, 2013, May-01, Volume: 105

    Topics: Administration, Inhalation; Animals; Antibiotics, Antitubercular; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Coumarins; Fluorescence; Immunoenzyme Techniques; Lactic Acid; Lung; Macrophages, Alveolar; Male; Microspheres; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rifampin; Thiazoles; Tissue Distribution; Trachea

2013
Synthesis and pharmacological evaluation of some novel 2-(5-hydroxy-5-trifluoromethyl-4,5-dihydropyrazol-1-yl)-4-(coumarin-3-yl)thiazoles.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Dose-Response Relationship, Drug; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Male; Microbial Sensitivity Tests; Molecular Structure; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles

2013
Copper(II) triflate promoted multicomponent catalytic clubbing of piperazinyl-thiazoloquinolines and thiazolocoumarins as antimicrobials.
    Archiv der Pharmazie, 2013, Volume: 346, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Catalysis; Coumarins; Drug Design; Gram-Negative Bacteria; Gram-Positive Bacteria; Mesylates; Microbial Sensitivity Tests; Molecular Structure; Piperazines; Quinolines; Structure-Activity Relationship; Thiazoles

2013
Lactoferrin-modified PEG-co-PCL nanoparticles for enhanced brain delivery of NAP peptide following intranasal administration.
    Biomaterials, 2013, Volume: 34, Issue:15

    Topics: Acetylcholinesterase; Administration, Intranasal; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Brain; Carbocyanines; Cell Line; Choline O-Acetyltransferase; Coumarins; Drug Delivery Systems; Endocytosis; Humans; Ibotenic Acid; Lactoferrin; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Nanoparticles; Neuroprotective Agents; Peptides; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Thiazoles; Tissue Distribution

2013
Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel.
    Expert opinion on drug delivery, 2013, Volume: 10, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coumarins; Docetaxel; Drug Carriers; Half-Life; Humans; Liposomes; Male; Microscopy, Confocal; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Receptor, ErbB-2; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles; Trastuzumab; Vitamin E

2013
The transport pathways of polymer nanoparticles in MDCK epithelial cells.
    Biomaterials, 2013, Volume: 34, Issue:17

    Topics: Animals; Biological Transport; Coumarins; Dogs; Endocytosis; Epithelial Cells; Exocytosis; Flow Cytometry; Intracellular Space; L-Lactate Dehydrogenase; Light; Madin Darby Canine Kidney Cells; Microscopy, Confocal; Models, Biological; Nanoparticles; Organelles; Particle Size; Polymers; Protein Kinases; Scattering, Radiation; Thiazoles

2013
Enhanced uptake and cytotoxity of folate-conjugated mitoxantrone-loaded micelles via receptor up-regulation by dexamethasone.
    International journal of pharmaceutics, 2013, May-01, Volume: 448, Issue:1

    Topics: Antineoplastic Agents; Cell Survival; Coumarins; Dexamethasone; Endocytosis; Folate Receptor 1; Folic Acid; HeLa Cells; Humans; Micelles; Mitoxantrone; Phosphatidylethanolamines; Polyethylene Glycols; RNA, Messenger; Thiazoles; Up-Regulation

2013
Oligoarginine-modified biodegradable nanoparticles improve the intestinal absorption of insulin.
    International journal of pharmaceutics, 2013, May-01, Volume: 448, Issue:1

    Topics: Animals; Biological Availability; Blood Glucose; Caco-2 Cells; Cell Survival; Cell-Penetrating Peptides; Coumarins; Humans; Ileum; Insulin; Intestinal Absorption; L-Lactate Dehydrogenase; Lactic Acid; Male; Nanoparticles; Oligopeptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Thiazoles

2013
TPGS emulsified zein nanoparticles enhanced oral bioavailability of daidzin: in vitro characteristics and in vivo performance.
    Molecular pharmaceutics, 2013, May-06, Volume: 10, Issue:5

    Topics: Administration, Oral; Animals; Biological Availability; Biological Transport, Active; Caco-2 Cells; Coumarins; Drug Delivery Systems; Emulsions; Humans; Intestinal Absorption; Isoflavones; Male; Mice; Nanoparticles; Phytoestrogens; Polyethylene Glycols; Solutions; Thiazoles; Vitamin E; Zein

2013
Concanavalin A-conjugated poly(ethylene glycol)-poly(lactic acid) nanoparticles for intranasal drug delivery to the cervical lymph nodes.
    Journal of microencapsulation, 2013, Volume: 30, Issue:8

    Topics: Administration, Intranasal; Animals; Cell Line, Tumor; Cervix Uteri; Concanavalin A; Coumarins; Drug Carriers; Drug Delivery Systems; Female; Humans; Lactates; Lymph Nodes; Male; Nanoparticles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Thiazoles

2013
Paclitaxel-loaded poly(glycolide-co-ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 2000 succinate nanoparticles for lung cancer therapy.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Survival; Coumarins; Drug Delivery Systems; Humans; Lung Neoplasms; Mice; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Paclitaxel; Polyesters; Polyethylene Glycols; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays

2013
Comparison of antithrombotic and hemorrhagic effects of edoxaban, a novel factor Xa inhibitor, with unfractionated heparin, dalteparin, lepirudin and warfarin in rats.
    Thrombosis research, 2013, Volume: 132, Issue:2

    Topics: Animals; Anticoagulants; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Heparin; Hirudins; Male; Pyridines; Rats; Rats, Wistar; Recombinant Proteins; Thiazoles; Thromboembolism; Warfarin

2013
Dual evaluation of some novel 2-amino-substituted coumarinylthiazoles as anti-inflammatory-antimicrobial agents and their docking studies with COX-1/COX-2 active sites.
    Journal of enzyme inhibition and medicinal chemistry, 2014, Volume: 29, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Catalytic Domain; Coumarins; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiazoles

2014
Drug delivery to the ocular posterior segment using lipid emulsion via eye drop administration: effect of emulsion formulations and surface modification.
    International journal of pharmaceutics, 2013, Sep-10, Volume: 453, Issue:2

    Topics: Administration, Ophthalmic; Animals; Animals, Outbred Strains; Chemistry, Pharmaceutical; Chitosan; Coumarins; Emulsions; Lipids; Male; Mice; Ophthalmic Solutions; Poloxamer; Retina; Surface Properties; Thiazoles

2013
Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy.
    Acta biomaterialia, 2013, Volume: 9, Issue:11

    Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, Gel; Coumarins; Docetaxel; Female; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Spectroscopy; Mannitol; MCF-7 Cells; Molecular Weight; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Taxoids; Thermogravimetry; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays

2013
Inhibition of the growth factor MDK/midkine by a novel small molecule compound to treat non-small cell lung cancer.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Coumarins; Cytokines; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Midkine; Molecular Weight; Neoplasms, Experimental; Nerve Growth Factors; Phosphatidylinositol 3-Kinases; RNA, Small Interfering; Signal Transduction; Thiazoles; Tumor Burden; Vascular Endothelial Growth Factor A

2013
Glioma targeting and anti-glioma effect of interleukin 13 peptide and RGD peptide dual functionalized nanoparticles.
    Current pharmaceutical biotechnology, 2014, Volume: 14, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Coumarins; Drug Delivery Systems; Fluorescent Dyes; Glioma; Interleukin-13; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Oligopeptides; Particle Size; Thiazoles

2014
[Effects of sub-micro emulsion composition on cellular disposition of incorporated lipophilic drug].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2013, Volume: 42, Issue:5

    Topics: Anions; Cations; Coumarins; Emulsions; Endocytosis; HeLa Cells; Humans; Surface-Active Agents; Thiazoles

2013
Study and evaluation of mechanisms of dual targeting drug delivery system with tumor microenvironment assays compared with normal assays.
    Acta biomaterialia, 2014, Volume: 10, Issue:2

    Topics: Animals; Apoptosis; Biological Assay; Brain Neoplasms; Cell Death; Cell Proliferation; Coumarins; Drug Delivery Systems; Endocytosis; Glioma; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Spheroids, Cellular; Thiazoles; Tumor Microenvironment

2014
[Edoxaban is safer than vitamin K antagonists].
    MMW Fortschritte der Medizin, 2013, Sep-26, Volume: 155, Issue:16

    Topics: Administration, Oral; Anticoagulants; Hemorrhage; Humans; Pulmonary Embolism; Pyridines; Randomized Controlled Trials as Topic; Secondary Prevention; Thiazoles; Venous Thrombosis; Vitamin K; Warfarin

2013
[Transcellular process of coumarin 6 loaded PEG-PCL micelles on MDCK epithelial cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:9

    Topics: Animals; Biological Transport; Coumarins; Dogs; Drug Carriers; Drug Delivery Systems; Lactones; Madin Darby Canine Kidney Cells; Micelles; Particle Size; Polyethylene Glycols; Thiazoles

2013
Another novel oral anticoagulant matches warfarin.
    JAMA, 2014, Jan-15, Volume: 311, Issue:3

    Topics: Anticoagulants; Atrial Fibrillation; Embolism; Hemorrhage; Humans; Pyridines; Randomized Controlled Trials as Topic; Risk; Stroke; Thiazoles; Warfarin

2014
Mixed IR/Vis two-dimensional spectroscopy: chemical exchange beyond the vibrational lifetime and sub-ensemble selective photochemistry.
    Angewandte Chemie (International ed. in English), 2014, Mar-03, Volume: 53, Issue:10

    Topics: Coumarins; Molecular Structure; Photochemical Processes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiazoles; Time Factors; Vibration

2014
pH and glutathion-responsive hydrogel for localized delivery of paclitaxel.
    Colloids and surfaces. B, Biointerfaces, 2014, Apr-01, Volume: 116

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Drug Carriers; Glutathione; HeLa Cells; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogen-Ion Concentration; MCF-7 Cells; Paclitaxel; Particle Size; Structure-Activity Relationship; Surface Properties; Thiazoles

2014
Comparison of the phase III clinical trial designs of novel oral anticoagulants versus warfarin for the treatment of nonvalvular atrial fibrillation: implications for clinical practice.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:2

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials, Phase III as Topic; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Research Design; Rivaroxaban; Thiazoles; Thiophenes; Vitamin K; Warfarin

2014
iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas.
    Biomaterials, 2014, Volume: 35, Issue:14

    Topics: Administration, Intravenous; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Coumarins; Drug Combinations; Endocytosis; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Kaplan-Meier Estimate; Lactic Acid; Laminin; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteoglycans; Rats; Rats, Sprague-Dawley; Spectroscopy, Near-Infrared; Thiazoles; Tissue Distribution; Treatment Outcome

2014
In vitro and in vivo intracellular distribution and anti-glioblastoma effects of docetaxel-loaded nanoparticles functioned with IL-13 peptide.
    International journal of pharmaceutics, 2014, May-15, Volume: 466, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Coumarins; Docetaxel; Drug Delivery Systems; Glioblastoma; Humans; Interleukin-13; Male; Mice, Inbred BALB C; Nanoparticles; Peptides; Taxoids; Thiazoles

2014
A magnetic nanoparticle stabilized gas containing emulsion for multimodal imaging and triggered drug release.
    Pharmaceutical research, 2014, Volume: 31, Issue:6

    Topics: Animals; Chemistry, Pharmaceutical; Contrast Media; Coumarins; Drug Carriers; Drug Delivery Systems; Emulsions; Gases; Liver; Magnetite Nanoparticles; Rats; Thiazoles; Tissue Distribution; Ultrasonics

2014
Ultrasound driven assembly of lignin into microcapsules for storage and delivery of hydrophobic molecules.
    Biomacromolecules, 2014, May-12, Volume: 15, Issue:5

    Topics: Animals; Capsules; CHO Cells; Coumarins; Cricetulus; Hydrophobic and Hydrophilic Interactions; Lignin; Molecular Structure; Particle Size; Sonication; Surface Properties; Thiazoles

2014
Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death.
    Bioorganic & medicinal chemistry, 2014, May-01, Volume: 22, Issue:9

    Topics: 4-Hydroxycoumarins; Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Coumarins; Humans; Isoxazoles; MCF-7 Cells; Poly(ADP-ribose) Polymerases; Thiazoles; U937 Cells

2014
Edoxaban or standard therapy with warfarin for stroke prevention in patients with atrial fibrillation?
    Future cardiology, 2014, Volume: 10, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Humans; Pyridines; Stroke; Thiazoles; Warfarin

2014
Perioperative management of patients on new oral anticoagulants.
    The British journal of surgery, 2014, Volume: 101, Issue:7

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Biological Availability; Clinical Trials as Topic; Dabigatran; Drug Monitoring; Elective Surgical Procedures; Emergencies; Half-Life; Hemorrhage; Humans; Medication Adherence; Morpholines; Preoperative Care; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Time Factors; Warfarin

2014
Parenteral thermo-sensitive organogel for schizophrenia therapy, in vitro and in vivo evaluation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Aug-18, Volume: 60

    Topics: Animals; Antipsychotic Agents; Coumarins; Drug Delivery Systems; Fatty Acids; Gels; Isoxazoles; Male; Mice, Nude; Paliperidone Palmitate; Phase Transition; Pyrimidines; Rats, Sprague-Dawley; Schizophrenia; Soybean Oil; Thiazoles; Transition Temperature; Viscosity

2014
A hybrid coumarin-thiazole fluorescent sensor for selective detection of bisulfite anions in vivo and in real samples.
    Chemistry, an Asian journal, 2014, Volume: 9, Issue:7

    Topics: Anions; Biosensing Techniques; Color; Coumarins; Female; Fluorescent Dyes; Humans; MCF-7 Cells; Molecular Structure; Sensitivity and Specificity; Sulfites; Thiazoles

2014
Direct oral anticoagulants in atrial fibrillation.
    Seminars in hematology, 2014, Volume: 51, Issue:2

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Embolism; Hemorrhage; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2014
Testing fluorescence lifetime standards using two-photon excitation and time-domain instrumentation: rhodamine B, coumarin 6 and lucifer yellow.
    Journal of fluorescence, 2014, Volume: 24, Issue:4

    Topics: Coumarins; Fluorescence; Fluorescent Dyes; Isoquinolines; Protons; Rhodamines; Spectrometry, Fluorescence; Thiazoles; Time Factors

2014
Critique of Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation trial.
    Stroke, 2014, Volume: 45, Issue:7

    Topics: Adult; Atrial Fibrillation; Dose-Response Relationship, Drug; Double-Blind Method; Factor Xa Inhibitors; Humans; Pyridines; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Treatment Outcome; Warfarin

2014
Nanoparticles as drug delivery system against tuberculosis in zebrafish embryos: direct visualization and treatment.
    ACS nano, 2014, Jul-22, Volume: 8, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Coumarins; Drug Carriers; Embryo, Nonmammalian; Granuloma; Lactic Acid; Macrophages; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Nanoparticles; Optical Imaging; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Rifampin; Thiazoles; Tuberculosis; Zebrafish

2014
Edoxaban in the evolving scenario of non vitamin K antagonist oral anticoagulants imputed placebo analysis and multiple treatment comparisons.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Administration, Oral; Anticoagulants; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Dabigatran; Factor Xa Inhibitors; Humans; Meta-Analysis as Topic; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Vitamin K; Warfarin

2014
Edoxaban versus warfarin for stroke prevention in non-valvular atrial fibrillation: a cost-effectiveness analysis.
    Journal of thrombosis and thrombolysis, 2015, Volume: 39, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Humans; Intracranial Hemorrhages; Italy; Markov Chains; Pyridines; Quality-Adjusted Life Years; Stroke; Thiazoles; Warfarin

2015
A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
    Drug development and industrial pharmacy, 2015, Volume: 41, Issue:7

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Oleanolic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Thiazoles; Vitamin E

2015
Nanocomplex based on biocompatible phospholipids and albumin for long-circulation applications.
    ACS applied materials & interfaces, 2014, Aug-27, Volume: 6, Issue:16

    Topics: Animals; Biocompatible Materials; Cattle; Cell Line; Coumarins; Drug Delivery Systems; Male; Mice; Nanoparticles; Particle Size; Phagocytosis; Phospholipids; Photoelectron Spectroscopy; Reproducibility of Results; Serum Albumin, Bovine; Static Electricity; Thiazoles

2014
Stable isotope labeling method for the investigation of protein haptenation by electrophilic skin sensitizers.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 142, Issue:1

    Topics: Acrolein; Chromatography, Liquid; Coumarins; Dermatitis, Contact; Dinitrochlorobenzene; Haptens; Humans; Isotope Labeling; Protein Binding; Serum Albumin; Skin; Tandem Mass Spectrometry; Thiazoles

2014
Eligibility and preference of new oral anticoagulants in patients with atrial fibrillation: comparison between patients with versus without stroke.
    Stroke, 2014, Volume: 45, Issue:10

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Dabigatran; Female; Humans; Male; Morpholines; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Research Design; Rivaroxaban; Stroke; Thiazoles; Thiophenes; Warfarin

2014
Once-daily edoxaban: a safer option than well-managed warfarin for patients with atrial fibrillation?
    European heart journal, 2014, Jul-21, Volume: 35, Issue:28

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Drug Administration Schedule; Factor Xa Inhibitors; Humans; Pyridines; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Warfarin

2014
Hyaluronic acid decorated lipid nanocarrier for MDR modulation and CD-44 targeting in colon adenocarcinoma.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Adenocarcinoma; Camptothecin; Colonic Neoplasms; Coumarins; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lipids; Nanoparticles; Thiazoles

2015
Dual-modality, fluorescent, PLGA encapsulated bismuth nanoparticles for molecular and cellular fluorescence imaging and computed tomography.
    Nanoscale, 2014, Nov-07, Volume: 6, Issue:21

    Topics: Animals; Apoptosis; Bismuth; Cell Proliferation; Cell Survival; Chickens; Contrast Media; Coumarins; Lactic Acid; Lysosomes; Male; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Temperature; Thiazoles; Tomography, X-Ray Computed; X-Ray Microtomography

2014
A thiazole coumarin (TC) turn-on fluorescence probe for AT-base pair detection and multipurpose applications in different biological systems.
    Scientific reports, 2014, Sep-25, Volume: 4

    Topics: Base Pairing; Carbocyanines; Cell Cycle; Coumarins; DNA; Flow Cytometry; Fluorescence; Fluorescent Dyes; HEK293 Cells; HeLa Cells; Humans; Molecular Imaging; Thiazoles

2014
Tuning the binding of coumarin 6 with DNA by molecular encapsulators: effect of β-cyclodextrin and C-hexylpyrogallol[4]arene.
    Journal of molecular recognition : JMR, 2014, Volume: 27, Issue:11

    Topics: Animals; beta-Cyclodextrins; Binding Sites; Cattle; Coumarins; DNA; Hydrogen Bonding; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pyrogallol; Thiazoles

2014
Novel anticoagulants eliminate the need for left atrial appendage exclusion devices.
    Circulation, 2014, Oct-21, Volume: 130, Issue:17

    Topics: Anticoagulants; Atrial Appendage; Atrial Fibrillation; Benzimidazoles; beta-Alanine; Clinical Trials as Topic; Dabigatran; Humans; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Septal Occluder Device; Stroke; Thiazoles; Thiophenes; Unnecessary Procedures; Warfarin

2014
Cellular uptake of coumarin-6 under microfluidic conditions into HCE-T cells from nanoscale formulations.
    Molecular pharmaceutics, 2015, Jan-05, Volume: 12, Issue:1

    Topics: Biological Availability; Cell Line; Cell Line, Tumor; Cell Survival; Cornea; Coumarins; Crystallization; Drug Delivery Systems; Drug Design; Epithelial Cells; Eye; Fluorometry; Humans; Lipids; Liposomes; Micelles; Microfluidic Analytical Techniques; Microfluidics; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Thiazoles

2015
Ingredients in fruit juices interact with dasatinib through inhibition of BCRP: a new mechanism of beverage-drug interaction.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:1

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Beverages; Biological Transport; Cell Line; Coumarins; Dasatinib; Dogs; Flavonoids; Food-Drug Interactions; Fruit; Humans; Madin Darby Canine Kidney Cells; Membrane Transport Modulators; Neoplasm Proteins; Phytochemicals; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Recombinant Proteins; Sus scrofa; Thiazoles

2015
One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies.
    Bioorganic & medicinal chemistry letters, 2015, Jan-01, Volume: 25, Issue:1

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA Cleavage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indoles; Thiazoles

2015
Surface association and uptake of poly(lactic-co-glycolic) acid nanoparticles by Aspergillus flavus.
    Therapeutic delivery, 2014, Volume: 5, Issue:11

    Topics: Aspergillus flavus; Chemistry, Pharmaceutical; Coumarins; Drug Carriers; Fluorescent Dyes; Hyphae; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Spores, Fungal; Surface Properties; Technology, Pharmaceutical; Thiazoles; Time Factors

2014
Intranasal and intravenous administration of octa-arginine modified poly(lactic-co-glycolic acid) nanoparticles facilitates central nervous system delivery of loperamide.
    The Journal of pharmacy and pharmacology, 2015, Volume: 67, Issue:4

    Topics: Administration, Intranasal; Administration, Intravenous; Analgesics; Animals; Arginine; Cell Line; Central Nervous System; Coumarins; Dogs; Drug Delivery Systems; Female; Lactic Acid; Loperamide; Male; Mice, Inbred C57BL; Nanoconjugates; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Thiazoles

2015
Delta-like ligand 4-targeted nanomedicine for antiangiogenic cancer therapy.
    Biomaterials, 2015, Volume: 42

    Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Movement; Cell Survival; Collagen; Coumarins; Drug Combinations; Drug Delivery Systems; Endocytosis; Female; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Laminin; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Nanomedicine; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Peptides; Proteoglycans; Rats, Sprague-Dawley; Subcutaneous Tissue; Thiazoles; Xenograft Model Antitumor Assays

2015
Comparison of differences in medical costs when new oral anticoagulants are used for the treatment of patients with non-valvular atrial fibrillation and venous thromboembolism vs warfarin or placebo in the US.
    Journal of medical economics, 2015, Volume: 18, Issue:6

    Topics: Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Costs and Cost Analysis; Dabigatran; Health Expenditures; Hemorrhage; Humans; Models, Econometric; Myocardial Infarction; Pulmonary Embolism; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; United States; Venous Thromboembolism; Warfarin

2015
In vitro characterization of 6-Coumarin loaded solid lipid nanoparticles and their uptake by immunocompetent fish cells.
    Colloids and surfaces. B, Biointerfaces, 2015, Mar-01, Volume: 127

    Topics: Animals; Calorimetry, Differential Scanning; Cell Line; Coumarins; Endocytosis; Flow Cytometry; Head Kidney; Immunocompetence; Lipids; Microscopy, Confocal; Microspheres; Nanoparticles; Sea Bream; Spectroscopy, Fourier Transform Infrared; Thiazoles

2015
Should patients on vitamin K antagonists be treated differently?
    European heart journal, 2015, Jun-14, Volume: 36, Issue:23

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Female; Humans; Male; Pyridines; Stroke; Thiazoles; Warfarin

2015
Synthesis, antioxidant and anticholinesterase activities of novel coumarylthiazole derivatives.
    Bioorganic chemistry, 2015, Volume: 59

    Topics: Acetylcholinesterase; Animals; Antioxidants; Butyrylcholinesterase; Cholinesterase Inhibitors; Coumarins; Electrophorus; Horses; Structure-Activity Relationship; Thiazoles; Urea

2015
Toxicity studies of coumarin 6-encapsulated polystyrene nanospheres conjugated with peanut agglutinin and poly(N-vinylacetamide) as a colonoscopic imaging agent in rats.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:5

    Topics: Acetamides; Animals; Body Weight; Caco-2 Cells; CHO Cells; Colon; Colonoscopy; Colorectal Neoplasms; Coumarins; Cricetulus; Drinking; Eating; Fluorescent Dyes; Humans; Male; Nanospheres; Peanut Agglutinin; Polystyrenes; Polyvinyls; Rats; Rectum; Thiazoles

2015
[New oral anticoagulants in venous thromboembolism. General practice information on switching, monitoring, pausing].
    MMW Fortschritte der Medizin, 2015, Jan-19, Volume: 157, Issue:1

    Topics: Anticoagulants; Benzimidazoles; beta-Alanine; Dabigatran; Drug Monitoring; Drug Substitution; Half-Life; Hemorrhage; Humans; Kidney Function Tests; Morpholines; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Thiophenes; Thromboembolism; Warfarin

2015
Pharmacogenomic testing and response to warfarin.
    Lancet (London, England), 2015, Jun-06, Volume: 385, Issue:9984

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Thiazoles; Warfarin

2015
Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases.
    Acta pharmaceutica (Zagreb, Croatia), 2015, Volume: 65, Issue:1

    Topics: 4-Hydroxycoumarins; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Isoxazoles; Lung Neoplasms; Thiazoles; Time Factors

2015
Synthesis of functionalized Pluronic-b-poly(ε-caprolactone) and the comparative study of their pendant groups on the cellular internalization behavior.
    Journal of materials science. Materials in medicine, 2015, Volume: 26, Issue:4

    Topics: Animals; Cell Line; Coumarins; Diffusion; Drug Carriers; Glioma; Materials Testing; Micelles; Particle Size; Polyethylenes; Polypropylenes; Rats; Subcellular Fractions; Thiazoles

2015
Adding vitamin E-TPGS to the formulation of Genexol-PM: specially mixed micelles improve drug-loading ability and cytotoxicity against multidrug-resistant tumors significantly.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Chemistry, Pharmaceutical; Coumarins; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Space; Lactic Acid; Micelles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Spheroids, Cellular; Thiazoles; Vitamin E

2015
A novel PI3K inhibitor iMDK suppresses non-small cell lung Cancer cooperatively with A MEK inhibitor.
    Experimental cell research, 2015, Jul-15, Volume: 335, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzamides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Coumarins; Diphenylamine; Drug Synergism; Female; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Thiazoles; Xenograft Model Antitumor Assays

2015
A Novel Approach to Inhibit Heat Shock Response as Anticancer Strategy by Coumarine Compounds Containing Thiazole Skeleton.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Heat-Shock Response; HSP90 Heat-Shock Proteins; Humans; Molecular Docking Simulation; Structure-Activity Relationship; Thiazoles

2015
Cost-effectiveness of anticoagulation in patients with nonvalvular atrial fibrillation with edoxaban compared to warfarin in Germany.
    BioMed research international, 2015, Volume: 2015

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Cost-Benefit Analysis; Dabigatran; Germany; Humans; Pyrazoles; Pyridines; Pyridones; Quality of Life; Quality-Adjusted Life Years; Rivaroxaban; Thiazoles; Warfarin

2015
Doxorubicin liposomes as an investigative model to study the skin permeation of nanocarriers.
    International journal of pharmaceutics, 2015, Jul-15, Volume: 489, Issue:1-2

    Topics: Animals; Antibiotics, Antineoplastic; Cell-Penetrating Peptides; Coumarins; Doxorubicin; Drug Carriers; Drug Liberation; Fluorescein-5-isothiocyanate; Fluorescence; Fluorescent Dyes; Gene Products, tat; In Vitro Techniques; Lipids; Male; Permeability; Polyethylene Glycols; Rats, Hairless; RNA, Small Interfering; Skin; Skin Absorption; Swine; Thiazoles

2015
Warfarin pharmacogenetics in the era of new oral anticoagulants.
    Clinical genetics, 2015, Volume: 88, Issue:2

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Thiazoles; Warfarin

2015
[Simplified therapy regimen receives recommendation for approval].
    MMW Fortschritte der Medizin, 2015, Jun-11, Volume: 157, Issue:11

    Topics: Atrial Fibrillation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Approval; Embolism; Humans; Pyridines; Recurrence; Stroke; Thiazoles; Venous Thromboembolism; Warfarin

2015
Edoxaban and amiodarone: interactions on multiple levels.
    European heart journal, 2015, Sep-01, Volume: 36, Issue:33

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Female; Humans; Male; Pyridines; Thiazoles; Warfarin

2015
Uses of 3-(2-Bromoacetyl)-2H-chromen-2-one in the Synthesis of Heterocyclic Compounds Incorporating Coumarin: Synthesis, Characterization and Cytotoxicity.
    Molecules (Basel, Switzerland), 2015, Jun-23, Volume: 20, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrans; Structure-Activity Relationship; Thiazoles

2015
The Effect of Hydrophilic and Hydrophobic Structure of Amphiphilic Polymeric Micelles on Their Transportation in Rats.
    Current drug delivery, 2016, Volume: 13, Issue:1

    Topics: Animals; Biological Transport; Coumarins; Dogs; Drug Carriers; Epithelial Cells; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Madin Darby Canine Kidney Cells; Male; Micelles; Nanoparticles; Phosphatidylethanolamines; Polyesters; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Thiazoles

2016
Targeting effect of PEGylated liposomes modified with the Arg-Gly-Asp sequence on gastric cancer.
    Oncology reports, 2015, Volume: 34, Issue:4

    Topics: Cell Tracking; Coumarins; Fibronectins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indocyanine Green; Integrin alpha5beta1; Liposomes; Microscopy, Confocal; Oligopeptides; Phosphatidylethanolamines; Polyethylene Glycols; Stomach Neoplasms; Thiazoles

2015
Effects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Apoptosis; Biocompatible Materials; Cell Line, Tumor; Coumarins; Docetaxel; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Micelles; Microscopy, Fluorescence; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles

2015
Modified NLC-loaded coumarin for pharmaceutical applications: the improvement of physical stability and controlled release profile.
    Pharmaceutical development and technology, 2016, Volume: 21, Issue:8

    Topics: Chemistry, Pharmaceutical; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Stability; Lipids; Nanostructures; Particle Size; Thiazoles; Workforce

2016
[The ENGAGE AF-TIMI 48 study].
    Giornale italiano di cardiologia (2006), 2015, Volume: 16, Issue:9

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Warfarin

2015
Intracellular localization and dynamics of Hypericin loaded PLLA nanocarriers by image correlation spectroscopy.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-28, Volume: 218

    Topics: Anthracenes; Biological Transport; Cell Line, Tumor; Coumarins; Drug Carriers; Fluorescent Dyes; Humans; Lactic Acid; Nanoparticles; Perylene; Polyesters; Polymers; Spectrum Analysis; Thiazoles

2015
Analysis of the Photophysical Behavior and Rotational-Relaxation Dynamics of Coumarin 6 in Nonionic Micellar Environments: The Effect of Temperature.
    Molecules (Basel, Switzerland), 2015, Oct-23, Volume: 20, Issue:10

    Topics: Coloring Agents; Coumarins; Fluorescence Polarization; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Micelles; Molecular Conformation; Particle Size; Temperature; Thiazoles; Viscosity

2015
Cost-effectiveness of edoxaban for the treatment of venous thromboembolism based on the Hokusai-VTE study.
    Hospital practice (1995), 2015, Volume: 43, Issue:5

    Topics: Adult; Anticoagulants; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Treatment Outcome; Venous Thromboembolism; Warfarin

2015
Controlled association and delivery of nanoparticles from jet-sprayed hybrid microfibrillar matrices.
    Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140

    Topics: Adsorption; Coumarins; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Electrophoresis, Polyacrylamide Gel; Lactic Acid; Microfibrils; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Muramidase; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles

2016
PEG-derivatized octacosanol as micellar carrier for paclitaxel delivery.
    International journal of pharmaceutics, 2016, Mar-16, Volume: 500, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line; Cell Line, Tumor; Cell Survival; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Fatty Alcohols; Female; Humans; Male; Maximum Tolerated Dose; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Rats, Sprague-Dawley; Thiazoles

2016
Understanding the influence of surface properties of nanoparticles and penetration enhancers for improving bioavailability in eye tissues in vivo.
    International journal of pharmaceutics, 2016, Mar-30, Volume: 501, Issue:1-2

    Topics: Animals; Benzalkonium Compounds; Biological Availability; Cell Line; Cell Survival; Coumarins; Decanoic Acids; Drug Delivery Systems; Edetic Acid; Eye; Gelatin; Glutaral; Glycolates; Mice; Microscopy, Electron, Scanning; Mucins; Nanoparticles; Permeability; Polymers; Rabbits; Surface Properties; Taurocholic Acid; Thiazoles

2016
[In vitro targeting effect of lactoferrin modified PEGylated liposomes for hepatoma cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:10

    Topics: Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Coumarins; Drug Delivery Systems; Endocytosis; Hep G2 Cells; Humans; Lactoferrin; Liposomes; Liver Neoplasms; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Thiazoles

2015
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bufanolides; Coumarins; Drug Carriers; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles; Vitamin E

2016
Preparation of magnetic and pH-responsive chitosan microcapsules via sonochemical method.
    Journal of microencapsulation, 2016, Volume: 33, Issue:2

    Topics: Chitosan; Coumarins; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Hydrogen-Ion Concentration; Magnetics; Magnetite Nanoparticles; Oleic Acid; Particle Size; Sonication; Thiazoles

2016
Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment.
    Colloids and surfaces. B, Biointerfaces, 2016, May-01, Volume: 141

    Topics: A549 Cells; Alkaline Phosphatase; Animals; Antineoplastic Agents; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Cycle; Cell Survival; Coated Materials, Biocompatible; Coumarins; Docetaxel; Drug Liberation; Humans; L-Lactate Dehydrogenase; Lung; Lung Neoplasms; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanotubes, Carbon; Rats; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Taxoids; Thiazoles; Vitamin E

2016
Design, synthesis and biological evaluation of novel coumarin thiazole derivatives as α-glucosidase inhibitors.
    Bioorganic chemistry, 2016, Volume: 65

    Topics: alpha-Glucosidases; Coumarins; Dose-Response Relationship, Drug; Drug Design; Glycoside Hydrolase Inhibitors; Molecular Docking Simulation; Molecular Structure; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiazoles

2016
Cost-Effectiveness of High-Dose Edoxaban Compared with Adjusted-Dose Warfarin for Stroke Prevention in Non-Valvular Atrial Fibrillation Patients.
    Pharmacotherapy, 2016, Volume: 36, Issue:5

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Male; Markov Chains; Pyridines; Quality-Adjusted Life Years; Stroke; Thiazoles; Warfarin

2016
Cost-Effectiveness of Oral Anticoagulants for Ischemic Stroke Prophylaxis Among Nonvalvular Atrial Fibrillation Patients.
    Stroke, 2016, Volume: 47, Issue:6

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Brain Ischemia; Cost-Benefit Analysis; Dabigatran; Humans; Insurance, Health; Middle Aged; Models, Theoretical; Pyrazoles; Pyridines; Pyridones; Quality-Adjusted Life Years; Risk; Rivaroxaban; Severity of Illness Index; Stroke; Thiazoles; Warfarin

2016
Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish.
    ACS applied materials & interfaces, 2016, 05-25, Volume: 8, Issue:20

    Topics: Animals; Biological Transport; Coumarins; Dogs; Madin Darby Canine Kidney Cells; Nanoparticles; Organelles; Particle Size; Thiazoles; Zebrafish

2016
Comparative study of hemorrhagic and ischemic complications among anticoagulants in patients undergoing cryoballoon ablation for atrial fibrillation.
    Journal of cardiology, 2017, Volume: 69, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Brain; Brain Ischemia; Cryosurgery; Dabigatran; Embolism; Female; Hemorrhage; Humans; Incidence; Magnetic Resonance Imaging; Male; Middle Aged; Postoperative Complications; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2017
Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer.
    Nanomedicine (London, England), 2016, Volume: 11, Issue:11

    Topics: A549 Cells; Animals; Antineoplastic Agents; Benzimidazoles; Benzoates; Coumarins; Docetaxel; Female; Heterografts; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Particle Size; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Surface Properties; Taxoids; Telmisartan; Thiazoles; Tumor Burden

2016
The Effect of Millisecond Pulsed Electric Fields (msPEF) on Intracellular Drug Transport with Negatively Charged Large Nanocarriers Made of Solid Lipid Nanoparticles (SLN): In Vitro Study.
    The Journal of membrane biology, 2016, Volume: 249, Issue:5

    Topics: Animals; Biological Transport; Calorimetry, Differential Scanning; Cell Line; Cell Survival; Coumarins; Cytoskeleton; Drug Carriers; Drug Delivery Systems; Electroporation; Flow Cytometry; Humans; Lipids; Microscopy, Fluorescence; Molecular Structure; Nanoparticles; Particle Size; Thiazoles

2016
Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer.
    Experimental cell research, 2016, 08-01, Volume: 346, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Migration Assays; Cell Movement; Coumarins; Docetaxel; Drug Carriers; Enzyme Activation; Fluorescent Antibody Technique; Humans; JNK Mitogen-Activated Protein Kinases; Liposomes; Mice; Microtubules; Nanoparticles; Noscapine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polymerization; Staining and Labeling; Taxoids; Thiazoles; Triple Negative Breast Neoplasms; Tubulin; Xenograft Model Antitumor Assays

2016
Anticoagulants: What is new and what is the standard?
    Clinical pharmacology and therapeutics, 2016, Volume: 100, Issue:2

    Topics: Administration, Oral; Anticoagulants; Dabigatran; Factor Xa Inhibitors; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2016
Novel Midkine Inhibitor iMDK Inhibits Tumor Growth and Angiogenesis in Oral Squamous Cell Carcinoma.
    Anticancer research, 2016, Volume: 36, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Coumarins; Cytokines; Female; Humans; Mice; Mice, Inbred BALB C; Midkine; Mouth Neoplasms; Neovascularization, Pathologic; Thiazoles

2016
Effects of transferrin conjugated multi-walled carbon nanotubes in lung cancer delivery.
    Materials science & engineering. C, Materials for biological applications, 2016, Oct-01, Volume: 67

    Topics: A549 Cells; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Cycle; Coumarins; Docetaxel; Drug Delivery Systems; Drug Liberation; Endocytosis; Flow Cytometry; Humans; Intracellular Space; Lung; Lung Neoplasms; Microscopy, Atomic Force; Nanotubes, Carbon; Particle Size; Rats; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Staining and Labeling; Static Electricity; Taxoids; Thiazoles; Transferrin

2016
Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation.
    Thrombosis and haemostasis, 2016, 08-30, Volume: 116, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Clinical Trials, Phase III as Topic; Hemorrhage; Humans; Models, Statistical; Pyridines; Randomized Controlled Trials as Topic; Risk Factors; Thiazoles; Thromboembolism; Warfarin

2016
Pharmacokinetic Interactions Between Mirabegron and Metformin, Warfarin, Digoxin or Combined Oral Contraceptives.
    European journal of drug metabolism and pharmacokinetics, 2017, Volume: 42, Issue:3

    Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adult; Area Under Curve; Contraceptives, Oral, Combined; Digoxin; Double-Blind Method; Drug Interactions; Female; Healthy Volunteers; Humans; Male; Metformin; Thiazoles; Urinary Bladder, Overactive; Warfarin

2017
Syntheses of new 3-thiazolyl coumarin derivatives, in vitro α-glucosidase inhibitory activity, and molecular modeling studies.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: alpha-Glucosidases; Chemistry Techniques, Synthetic; Coumarins; Glycoside Hydrolase Inhibitors; Molecular Docking Simulation; Protein Conformation; Thiazoles

2016
Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, 12-28, Volume: 244, Issue:Pt B

    Topics: Cell Line, Tumor; Cell Survival; Comet Assay; Coumarins; DNA Damage; Fatty Alcohols; Fluorescent Dyes; Hepatocytes; Humans; Interleukin-8; Nanoparticles; Poloxamer; Polyesters; Succinates; Thiazoles

2016
Novel Drug Delivery System for Dermal Uptake of Etofenamate: Semisolid SLN Dispersion.
    Current drug delivery, 2017, Volume: 14, Issue:3

    Topics: Administration, Cutaneous; Animals; Coumarins; Drug Delivery Systems; Flufenamic Acid; In Vitro Techniques; Male; Nanoparticles; Rats; Rats, Sprague-Dawley; Skin Absorption; Thiazoles

2017
Coumarin-thiazole and -oxadiazole derivatives: Synthesis, bioactivity and docking studies for aldose/aldehyde reductase inhibitors.
    Bioorganic chemistry, 2016, Volume: 68

    Topics: Aldehyde Reductase; Animals; Cattle; Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Molecular Docking Simulation; Molecular Structure; Oxadiazoles; Structure-Activity Relationship; Thiazoles

2016
Vitamin E TPGS modified liposomes enhance cellular uptake and targeted delivery of luteolin: An in vivo/in vitro evaluation.
    International journal of pharmaceutics, 2016, Oct-15, Volume: 512, Issue:1

    Topics: alpha-Tocopherol; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Coumarins; Drug Carriers; Female; Humans; Liposomes; Luteolin; Mice; Particle Size; Polyethylene Glycols; Thiazoles; Xenograft Model Antitumor Assays

2016
Impact of Substituents on Excited-State and Photosensitizing Properties in Cationic Iridium(III) Complexes with Ligands of Coumarin 6.
    Inorganic chemistry, 2016, Sep-06, Volume: 55, Issue:17

    Topics: 2,2'-Dipyridyl; Cations; Coordination Complexes; Coumarins; Iridium; Light; Luminescent Measurements; Models, Molecular; Photosensitizing Agents; Thiazoles

2016
A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis.
    Psychoneuroendocrinology, 2016, Volume: 74

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Coumarins; Disease Models, Animal; Female; Gene Expression; Mice; Mice, Inbred C57BL; Piperazines; Psychotic Disorders; Puerperal Disorders; Steryl-Sulfatase; Sulfonamides; Thiazoles

2016
Enhanced Bioactivity of α-Tocopheryl Succinate Based Block Copolymer Nanoparticles by Reduced Hydrophobicity.
    Macromolecular bioscience, 2016, Volume: 16, Issue:12

    Topics: alpha-Tocopherol; Antioxidants; Biocompatible Materials; Breast Neoplasms; Coumarins; Drug Delivery Systems; Female; Humans; Hydrophobic and Hydrophilic Interactions; Methacrylates; Nanoparticles; Polyethylene Glycols; Polymerization; Polymers; Thiazoles; Tumor Cells, Cultured

2016
Cost-effectiveness of non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation at high risk of bleeding and normal kidney function.
    Thrombosis research, 2017, Volume: 150

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Dabigatran; Hemorrhage; Humans; Markov Chains; Pyrazoles; Pyridines; Pyridones; Quality-Adjusted Life Years; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
Safety and efficacy of contemporary catheter ablation for atrial fibrillation patients with a history of cardioembolic stroke in the era of direct oral anticoagulants.
    Journal of cardiology, 2017, Volume: 70, Issue:1

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Catheter Ablation; Dabigatran; Female; Hemorrhage; Humans; Ischemic Attack, Transient; Male; Middle Aged; Pulmonary Veins; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Warfarin

2017
Edoxaban had similar efficacy to and better safety than warfarin in AF, regardless of previous stroke or TIA.
    Annals of internal medicine, 2016, 11-15, Volume: 165, Issue:10

    Topics: Humans; Pyridines; Stroke; Thiazoles; Warfarin

2016
Indirect Comparison of Novel Oral Anticoagulants in Women with Nonvalvular Atrial Fibrillation.
    Journal of women's health (2002), 2017, Volume: 26, Issue:3

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Hemorrhage; Humans; Odds Ratio; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Stroke; Thiazoles; Treatment Outcome; Warfarin

2017
Modelling projections for the uptake of edoxaban in an European population to 2050: effects on stroke, thromboembolism, and health economics perspectives.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2016, Volume: 18, Issue:10

    Topics: Administration, Oral; Atrial Fibrillation; Cost Savings; Cost-Benefit Analysis; Drug Costs; Europe; Factor Xa Inhibitors; Forecasting; Humans; Models, Economic; Practice Patterns, Physicians'; Pyridines; Stroke; Thiazoles; Thromboembolism; Time Factors; Treatment Outcome; Warfarin

2016
Acute management of stroke patients taking non-vitamin K antagonist oral anticoagulants Addressing Real-world Anticoagulant Management Issues in Stroke (ARAMIS) Registry: Design and rationale.
    American heart journal, 2016, Volume: 182

    Topics: Administration, Oral; Adult; Anticoagulants; Antithrombins; Atrial Fibrillation; Cohort Studies; Dabigatran; Emergency Treatment; Female; Humans; Male; Medication Therapy Management; Outcome and Process Assessment, Health Care; Pyrazoles; Pyridines; Pyridones; Quality Improvement; Registries; Rivaroxaban; Stroke; Thiazoles; United States; Warfarin

2016
Increasing the methodological quality and relevance of cost effectiveness analysis.
    Thrombosis research, 2017, Volume: 150

    Topics: Administration, Oral; Anticoagulants; Cost-Benefit Analysis; Decision Making; Humans; Probability; Pyridines; Thiazoles; Warfarin

2017
Co-delivery of docetaxel and curcumin prodrug via dual-targeted nanoparticles with synergistic antitumor activity against prostate cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Aconitic Acid; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Coumarins; Curcumin; Docetaxel; Drug Delivery Systems; Drug Liberation; Drug Stability; Drug Synergism; Endocytosis; Humans; Inhibitory Concentration 50; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prodrugs; Prostatic Neoplasms; Proton Magnetic Resonance Spectroscopy; Taxoids; Thiazoles

2017
Edoxaban Versus Warfarin: Bone Fractures Due to Falling.
    Journal of the American College of Cardiology, 2017, 01-31, Volume: 69, Issue:4

    Topics: Accidental Falls; Atrial Fibrillation; Fractures, Bone; Humans; Pyridines; Thiazoles; Warfarin

2017
Cholesterol-PEG comodified poly (N-butyl) cyanoacrylate nanoparticles for brain delivery: in vitro and in vivo evaluations.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Cell Survival; Cells, Cultured; Cholesterol; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Enbucrilate; Endothelial Cells; Mice; Nanoparticles; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Rabbits; Rats; Rats, Wistar; Thiazoles

2017
α-Tocopherol as functional excipient for resveratrol and coenzyme Q10-loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer.
    Journal of drug targeting, 2017, Volume: 25, Issue:6

    Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Area Under Curve; Biological Availability; Breast Neoplasms; Caco-2 Cells; Coumarins; Drug Delivery Systems; Emulsions; Excipients; Female; Humans; Nanoparticles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thiazoles; Ubiquinone

2017
Folic acid functionalized reduction-responsive magnetic chitosan nanocapsules for targeted delivery and triggered release of drugs.
    Carbohydrate polymers, 2017, Jul-15, Volume: 168

    Topics: Chitosan; Coumarins; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Humans; Magnetics; Nanocapsules; Thiazoles

2017
Is it reasonable to use a lower DOACs dose in some patients with VTE? Yes.
    Internal and emergency medicine, 2017, Volume: 12, Issue:5

    Topics: Administration, Oral; Anticoagulants; Dabigatran; Dose-Response Relationship, Drug; Evidence-Based Medicine; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Venous Thromboembolism; Warfarin

2017
Cost-Effectiveness of Edoxaban vs. Warfarin in Patients with Atrial Fibrillation Based on Results of the ENGAGE AF - TIMI 48 Trial: Taiwanese Perspective.
    Value in health regional issues, 2017, Volume: 12

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Clinical Trials as Topic; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Monitoring; Factor Xa Inhibitors; Female; Humans; Male; Pyridines; Quality-Adjusted Life Years; Taiwan; Thiazoles; Warfarin

2017
Ex Vivo and in Vivo Evaluation of the Effect of Coating a Coumarin-6-Labeled Nanostructured Lipid Carrier with Chitosan-N-acetylcysteine on Rabbit Ocular Distribution.
    Molecular pharmaceutics, 2017, 08-07, Volume: 14, Issue:8

    Topics: Acetylcysteine; Animals; Chitosan; Cornea; Coumarins; Drug Carriers; Eye; Lipids; Nanoparticles; Nanostructures; Rabbits; Thiazoles

2017
Choice of oral anticoagulants in older patients with non-valvular atrial fibrillation.
    British journal of hospital medicine (London, England : 2005), 2017, Jul-02, Volume: 78, Issue:7

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Craniocerebral Trauma; Dabigatran; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; Pyrazoles; Pyridines; Pyridones; Stroke; Thiazoles; Warfarin

2017
Non-vitamin K oral anticoagulants are non-inferior for stroke prevention but cause fewer major bleedings than well-managed warfarin: A retrospective register study.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Hemorrhage; Humans; Male; Middle Aged; Proportional Hazards Models; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
A comparison between vitamin K antagonists and new oral anticoagulants.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:11

    Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials, Phase III as Topic; Dabigatran; Humans; Intracranial Hemorrhages; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Vitamin K; Warfarin

2017
The reversion of anti-cancer drug antagonism of tamoxifen and docetaxel by the hyaluronic acid-decorated polymeric nanoparticles.
    Pharmacological research, 2017, Volume: 126

    Topics: A549 Cells; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coumarins; Docetaxel; Female; Humans; Hyaluronic Acid; Male; MCF-7 Cells; Mice; Nanoparticles; Polymers; Tamoxifen; Taxoids; Thiazoles

2017
Edoxaban was Effective for Treating Renal Vein Thrombosis in a Patient with Nephrotic Syndrome.
    Internal medicine (Tokyo, Japan), 2017, Sep-01, Volume: 56, Issue:17

    Topics: Adult; Factor Xa Inhibitors; Heparin; Humans; Male; Nephrotic Syndrome; Pulmonary Embolism; Pyridines; Renal Veins; Thiazoles; Treatment Outcome; Venous Thrombosis; Warfarin

2017
New Oral Anticoagulants: What Prescribers Should Know; Differences and Similarities between Warfarin and "New Agents" (Dabigatran, Rivaroxaban, Apixaban, Edoxaban) - Review of Indications, Contraindications and Safety of Use.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2016, Volume: 69, Issue:8

    Topics: Administration, Oral; Anticoagulants; Dabigatran; Diet; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Thiazoles; Warfarin

2016
Synthesis, molecular docking studies of coumarinyl-pyrazolinyl substituted thiazoles as non-competitive inhibitors of mushroom tyrosinase.
    Bioorganic chemistry, 2017, Volume: 74

    Topics: Agaricales; Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Molecular Docking Simulation; Molecular Structure; Monophenol Monooxygenase; Pyrazoles; Structure-Activity Relationship; Thiazoles

2017
Thiol-ene miniemulsion polymerization of a biobased monomer for biomedical applications.
    Colloids and surfaces. B, Biointerfaces, 2017, Nov-01, Volume: 159

    Topics: Animals; Coumarins; Emulsions; Fibroblasts; HeLa Cells; Humans; Mice; Nanoparticles; Polymerization; Polymers; Thiazoles

2017
Transport mechanism of chitosan-N-acetylcysteine, chitosan oligosaccharides or carboxymethyl chitosan decorated coumarin-6 loaded nanostructured lipid carriers across the rabbit ocular.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 120

    Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Chitosan; Cornea; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Excipients; Lipids; Male; Nanostructures; Oligosaccharides; Ophthalmic Solutions; Particle Size; Permeability; Rabbits; Thiazoles

2017
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
    Journal of natural products, 2017, 09-22, Volume: 80, Issue:9

    Topics: Anti-Inflammatory Agents; Antioxidants; Coumarins; Cyclooxygenase Inhibitors; Lipid Peroxidation; Molecular Structure; Plant Extracts; Tetrazoles; Tetrazolium Salts; Thiazoles

2017
Poly(vinyl methyl ether/maleic anhydride)-Doped PEG-PLA Nanoparticles for Oral Paclitaxel Delivery To Improve Bioadhesive Efficiency.
    Molecular pharmaceutics, 2017, 10-02, Volume: 14, Issue:10

    Topics: A549 Cells; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; HT29 Cells; Humans; Intestinal Mucosa; Male; Maleates; Mice; Models, Animal; Nanoparticles; Paclitaxel; Permeability; Polyesters; Polyethylene Glycols; Polyethylenes; Rats; Rats, Sprague-Dawley; Thiazoles

2017
Synthesis and evaluation of coumarin derivatives against human lung cancer cell lines.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Sep-12, Volume: 50, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Coumarins; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Reference Values; Reproducibility of Results; Tetrazolium Salts; Thiazoles

2017
Inhibition of Midkine Suppresses Prostate Cancer CD133
    The American journal of the medical sciences, 2017, Volume: 354, Issue:3

    Topics: AC133 Antigen; Antineoplastic Agents; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Coumarins; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Humans; Male; Midkine; Neoplastic Stem Cells; Nerve Growth Factors; Prostatic Neoplasms; RNA, Small Interfering; Thiazoles; Time Factors

2017
Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:6

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Dabigatran; Hemorrhage; Humans; Kidney Failure, Chronic; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Renal Dialysis; Rivaroxaban; Stroke; Thiazoles; Warfarin

2017
High-density lipoprotein mutant eye drops for the treatment of posterior eye diseases.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, Nov-28, Volume: 266

    Topics: Angiogenesis Inhibitors; Animals; Apolipoprotein A-I; Cell-Penetrating Peptides; Choroidal Neovascularization; Coumarins; Drug Carriers; Indazoles; Lipoproteins, HDL; Liposomes; Male; Mice, Inbred C57BL; Mutation; Nanoparticles; Ophthalmic Solutions; Pyrimidines; Sulfonamides; Thiazoles

2017
Analysis of Recurrent Stroke Volume and Prognosis between Warfarin and Four Non-Vitamin K Antagonist Oral Anticoagulants' Administration for Secondary Prevention of Stroke.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Humans; Japan; Magnetic Resonance Imaging; Male; Pyrazoles; Pyridines; Pyridones; Recurrence; Retrospective Studies; Risk Factors; Rivaroxaban; Secondary Prevention; Stroke; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2018
Zebrafish: A Visual Model To Evaluate the Biofate of Transferrin Receptor-Targeted 7Peptide-Decorated Coumarin 6 Micelles.
    ACS applied materials & interfaces, 2017, Nov-08, Volume: 9, Issue:44

    Topics: Animals; Coumarins; Drug Carriers; Drug Delivery Systems; Micelles; Polyesters; Polyethylene Glycols; Receptors, Transferrin; Thiazoles; Zebrafish

2017
Edoxaban improves acute venous thromboembolism while preserving protein C and protein S levels.
    Journal of cardiology, 2018, Volume: 71, Issue:3

    Topics: Acute Disease; Aged; Anticoagulants; Antithrombin III; Female; Humans; Male; Middle Aged; Protein C; Protein S; Pulmonary Embolism; Pyridines; Thiazoles; Treatment Outcome; Venous Thromboembolism; Warfarin

2018
Release Properties and Cellular Uptake in Caco-2 Cells of Size-Controlled Chitosan Nanoparticles.
    Journal of agricultural and food chemistry, 2017, Dec-20, Volume: 65, Issue:50

    Topics: Biological Transport; Caco-2 Cells; Cells; Chemistry, Pharmaceutical; Chitosan; Coumarins; Drug Carriers; Humans; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Thiazoles

2017
pH-sensitive polymeric nanoparticles with antioxidant and anti-inflammatory properties against cisplatin-induced hearing loss.
    Journal of controlled release : official journal of the Controlled Release Society, 2018, 01-28, Volume: 270

    Topics: alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cisplatin; Coumarins; Dexamethasone; Hearing Loss; Hydrogen-Ion Concentration; Ibuprofen; Nanoparticles; Polymers; Rats, Wistar; Thiazoles

2018
Piecemeal Rekindling of Coumarin 6 Fluorescence on Stepwise Unfolding of Protein by Surfactant.
    The journal of physical chemistry. B, 2017, 12-28, Volume: 121, Issue:51

    Topics: Animals; Cattle; Coumarins; Fluorescence; Hydrophobic and Hydrophilic Interactions; Protein Unfolding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Surface-Active Agents; Thiazoles

2017
Study protocol for the dabigatran, apixaban, rivaroxaban, edoxaban, warfarin comparative effectiveness research study.
    Journal of comparative effectiveness research, 2018, Volume: 7, Issue:1

    Topics: Anticoagulants; Antithrombins; Comparative Effectiveness Research; Dabigatran; Factor Xa Inhibitors; Humans; Pulmonary Embolism; Pyrazoles; Pyridines; Pyridones; Research Design; Rivaroxaban; Thiazoles; Venous Thrombosis; Warfarin

2018
CO
    Acta biomaterialia, 2018, 03-01, Volume: 68

    Topics: Animals; Biocompatible Materials; Carbon Dioxide; Coumarins; Giant Cells; Nanofibers; Polyesters; Rats, Sprague-Dawley; Thiazoles; Tissue Engineering; Tissue Scaffolds

2018
Comparison of Direct Oral Anticoagulants and Warfarin in the Treatment of Deep Venous Thrombosis in the Chronic Phase.
    International heart journal, 2018, Jan-27, Volume: 59, Issue:1

    Topics: Administration, Oral; Aged; Anticoagulants; Antithrombins; Chronic Disease; Dabigatran; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Female; Humans; Male; Pyrazoles; Pyridines; Pyridones; Recurrence; Thiazoles; Treatment Outcome; Ultrasonography; Venous Thrombosis; Warfarin

2018
Reversible Parkinsonism and Multiple Cerebral Infarctions after Pulmonary Endarterectomy in a Patient with Antiphospholipid Syndrome.
    Internal medicine (Tokyo, Japan), 2018, Jul-15, Volume: 57, Issue:14

    Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Cerebral Infarction; Chronic Disease; Endarterectomy; Heparin; Humans; Hypertension, Pulmonary; Male; Parkinsonian Disorders; Postoperative Complications; Pyridines; Thiazoles; Treatment Outcome; Warfarin

2018
Characteristics of Symptomatic Intracerebral Hemorrhage in Patient Receiving Direct Oral Anticoagulants: Comparison with Warfarin.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Cerebral Hemorrhage; Circadian Rhythm; Female; Humans; Male; Middle Aged; Prothrombin Time; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Risk Factors; Rivaroxaban; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2018
Understanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Coumarins; Drug Delivery Systems; Endocytosis; Exocytosis; Humans; Lactic Acid; Lysosomes; Microscopy, Confocal; Models, Biological; Nanomedicine; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Round Window, Ear; Thiazoles

2018
Successful Application of Edoxaban in the Treatment of Venous Thromboembolism Recurrence in a Patient with Non-small Cell Lung Cancer after Tumor Shrinkage.
    Internal medicine (Tokyo, Japan), 2018, Jun-15, Volume: 57, Issue:12

    Topics: Aged; Anticoagulants; Carcinoma, Non-Small-Cell Lung; Heparin; Humans; Lung Neoplasms; Male; Pyridines; Thiazoles; Tumor Burden; Venous Thromboembolism; Warfarin

2018
MHI-148 Cyanine Dye Conjugated Chitosan Nanomicelle with NIR Light-Trigger Release Property as Cancer Targeting Theranostic Agent.
    Molecular imaging and biology, 2018, Volume: 20, Issue:4

    Topics: Animals; Carbocyanines; Cell Line; Chitosan; Coloring Agents; Coumarins; Humans; Hyperthermia, Induced; Light; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Phototherapy; Spectroscopy, Near-Infrared; Theranostic Nanomedicine; Thiazoles; Tissue Distribution

2018
Albumin-covered lipid nanocapsules exhibit enhanced uptake performance by breast-tumor cells.
    Colloids and surfaces. B, Biointerfaces, 2018, May-01, Volume: 165

    Topics: Breast Neoplasms; Cell Proliferation; Cell Survival; Coumarins; Curcumin; Drug Liberation; Endocytosis; Female; Humans; Lipids; MCF-7 Cells; Nanocapsules; Serum Albumin; Thiazoles

2018
Synthesis of Novel Thiophene, Thiazole and Coumarin Derivatives Based on Benzimidazole Nucleus and Their Cytotoxicity and Toxicity Evaluations.
    Chemical & pharmaceutical bulletin, 2018, Volume: 66, Issue:3

    Topics: Anilides; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Decapoda; Drug Screening Assays, Antitumor; Humans; Larva; Quinolines; Structure-Activity Relationship; Thiazoles; Thiophenes

2018
Differences in activated clotting time and initial heparin dosage during atrial fibrillation ablation for patients with edoxaban compared with warfarin.
    Journal of cardiovascular electrophysiology, 2018, Volume: 29, Issue:6

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Catheter Ablation; Factor Xa Inhibitors; Female; Heparin; Humans; Male; Middle Aged; Perioperative Period; Predictive Value of Tests; Pyridines; Thiazoles; Time Factors; Treatment Outcome; Warfarin; Whole Blood Coagulation Time

2018
[The efficacy and safety of edoxaban in non-valvular atrial fibrillation].
    Orvosi hetilap, 2018, Volume: 159, Issue:12

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Humans; Pyridines; Randomized Controlled Trials as Topic; Thiazoles; Thrombolytic Therapy; Warfarin

2018
Tromboc@t Working Group recommendations for management in patients receiving direct oral anticoagulants.
    Medicina clinica, 2018, 09-14, Volume: 151, Issue:5

    Topics: Administration, Oral; Age Factors; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Embolism; Humans; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2018
Trastuzumab- and Fab' fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Cell Death; Cell Line, Tumor; Coumarins; Curcumin; Endocytosis; Female; Flow Cytometry; Humans; Immunoglobulin Fab Fragments; Injections, Intravenous; Mice, Inbred BALB C; Microscopy, Fluorescence; Nanoparticles; Polyesters; Polyethylene Glycols; Rats, Sprague-Dawley; Thiazoles; Tissue Distribution; Trastuzumab

2018
Hospital length of stay in patients initiated on direct oral anticoagulants versus warfarin for venous thromboembolism: a real-world single-center study.
    Journal of thrombosis and thrombolysis, 2018, Volume: 46, Issue:1

    Topics: Adult; Aged; Anticoagulants; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Length of Stay; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Thiazoles; Venous Thromboembolism; Warfarin

2018
pH-Triggered Drug Release of Monodispersed P(St-co-DMAEMA) Nanoparticles: Effects of Swelling, Polymer Chain Flexibility and Drug-Polymer Interactions.
    Journal of nanoscience and nanotechnology, 2017, Volume: 17, Issue:2

    Topics: Coumarins; Drug Carriers; Drug Liberation; Emulsions; Hydrogen-Ion Concentration; Methacrylates; Nanoparticles; Polymers; Thiazoles

2017
Comparing the Cost Effectiveness of Non-vitamin K Antagonist Oral Anticoagulants with Well-Managed Warfarin for Stroke Prevention in Atrial Fibrillation Patients at High Risk of Bleeding.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2018, Volume: 18, Issue:4

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Cost-Benefit Analysis; Dabigatran; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Hemorrhage; Humans; Markov Chains; Pyrazoles; Pyridines; Pyridones; Quality-Adjusted Life Years; Risk Adjustment; Rivaroxaban; Stroke; Therapeutic Equivalency; Thiazoles; Warfarin

2018
Gastrointestinal Bleeding With Edoxaban Versus Warfarin: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis In Myocardial Infarction).
    Circulation. Cardiovascular quality and outcomes, 2018, Volume: 11, Issue:5

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Blood Coagulation; Dose-Response Relationship, Drug; Drug Monitoring; Factor Xa Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Thiazoles; Time Factors; Treatment Outcome; Warfarin

2018
Abnormal vaginal bleeding in the 'DOAC' era.
    BJOG : an international journal of obstetrics and gynaecology, 2018, Volume: 125, Issue:12

    Topics: Female; Humans; Pyridines; Thiazoles; Uterine Hemorrhage; Venous Thromboembolism; Warfarin

2018
Efficiency of Biodegradable and pH-Responsive Polysuccinimide Nanoparticles (PSI-NPs) as Smart Nanodelivery Systems in Grapefruit: In Vitro Cellular Investigation.
    Macromolecular bioscience, 2018, Volume: 18, Issue:7

    Topics: Agrochemicals; Aspartic Acid; Bacterial Load; Cell Nucleus; Cells, Cultured; Citrus paradisi; Coumarins; Cytoplasm; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Nanoparticles; Particle Size; Peptides; Phloem; Plant Cells; Soil Microbiology; Static Electricity; Thiazoles

2018
Synthesis and biological evaluation of new coumarins bearing 2,4-diaminothiazole-5-carbonyl moiety.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Thiazoles

2018
Use of NOACs in the Peri-Operative Management of Patients with Atrial Fibrillation: To Stop, Bridge or Continue?
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:7

    Topics: Administration, Oral; Anticoagulants; Atrial Fibrillation; Humans; Pyridines; Thiazoles; Warfarin

2018
Role of Hypertension and Other Clinical Variables in Prognostication of Patients Presenting to the Emergency Department With Major Bleeding Events.
    Critical pathways in cardiology, 2018, Volume: 17, Issue:3

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Blood Glucose; Blood Transfusion; Cardiovascular Diseases; Creatinine; Dabigatran; Emergency Service, Hospital; Epistaxis; Female; Gastrointestinal Hemorrhage; Hematuria; Hemoptysis; Hemorrhage; Humans; Hypertension; Intracranial Hemorrhages; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Prognosis; Propensity Score; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Severity of Illness Index; Sex Factors; Thiazoles; Warfarin

2018
All-Cause Mortality Risk with Direct Oral Anticoagulants and Warfarin in the Primary Treatment of Venous Thromboembolism.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:9

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Dabigatran; Female; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Risk; Rivaroxaban; Survival Analysis; Thiazoles; Venous Thromboembolism; Warfarin

2018
New Hybrid Scaffolds based on Hydrazinyl Thiazole Substituted Coumarin; As Novel Leads of Dual Potential; In Vitro α-Amylase Inhibitory and Antioxidant (DPPH and ABTS Radical Scavenging) Activities.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2019, Volume: 15, Issue:1

    Topics: alpha-Amylases; Catalytic Domain; Coumarins; Enzyme Inhibitors; Free Radical Scavengers; Hydrazines; Ligands; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles

2019
Edoxaban in Latin America.
    Journal of the American College of Cardiology, 2018, 09-25, Volume: 72, Issue:13

    Topics: Atrial Fibrillation; Humans; Latin America; Pyridines; Thiazoles; Warfarin

2018
[Edoxaban in patients with atrial fibrillation and cancer].
    Giornale italiano di cardiologia (2006), 2018, Volume: 19, Issue:9 Suppl 1

    Topics: Anticoagulants; Atrial Fibrillation; Cancer Survivors; Cardiovascular Diseases; Embolism; Factor Xa Inhibitors; Hemorrhage; Humans; International Normalized Ratio; Neoplasms; Pyridines; Stroke; Thiazoles; Warfarin

2018
Novel ultra-small micelles based on rebaudioside A: A potential nanoplatform for ocular drug delivery.
    International journal of pharmaceutics, 2018, Dec-01, Volume: 552, Issue:1-2

    Topics: Administration, Ophthalmic; Animals; Cell Line; Cell Survival; Cornea; Coumarins; Diterpenes, Kaurane; Drug Delivery Systems; Humans; Mice; Micelles; Nanoparticles; Rabbits; Rats; Thiazoles

2018
Effects of phospholipid and polyethylene glycol monostearate (100) on the in vitro and in vivo physico-chemical characterization of poly(n-butyl cyanoacrylate) nanoparticles.
    Colloids and surfaces. B, Biointerfaces, 2019, Jan-01, Volume: 173

    Topics: Animals; Biological Transport; Caco-2 Cells; Coumarins; Drug Carriers; Emulsions; Enbucrilate; Fluorescent Dyes; Gastrointestinal Absorption; Glycine max; Humans; Jejunum; Male; Nanoparticles; Particle Size; Phospholipids; Polyethylene Glycols; Polymerization; Rats; Rats, Sprague-Dawley; Thiazoles

2019
Improved Stroke Prevention in Atrial Fibrillation After the Introduction of Non-Vitamin K Antagonist Oral Anticoagulants.
    Stroke, 2018, Volume: 49, Issue:9

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Brain Ischemia; Cohort Studies; Dabigatran; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stroke; Thiazoles; Warfarin

2018
Impact of Renal Function on Outcomes With Edoxaban in Real-World Patients With Atrial Fibrillation.
    Stroke, 2018, Volume: 49, Issue:10

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Embolism; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Pyridines; Stroke; Thiazoles; Warfarin

2018
Efficacy and Safety of Edoxaban in Patients With Active Malignancy and Atrial Fibrillation: Analysis of the ENGAGE AF - TIMI 48 Trial.
    Journal of the American Heart Association, 2018, 08-21, Volume: 7, Issue:16

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Comorbidity; Embolism; Factor Xa Inhibitors; Female; Gastrointestinal Neoplasms; Hemorrhage; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Proportional Hazards Models; Prostatic Neoplasms; Pyridines; Stroke; Thiazoles; Warfarin

2018
Prior Direct Oral Anticoagulant Therapy is Related to Small Infarct Volume and No Major Artery Occlusion in Patients With Stroke and Non-Valvular Atrial Fibrillation.
    Journal of the American Heart Association, 2018, 09-04, Volume: 7, Issue:17

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Cerebral Angiography; Dabigatran; Diffusion Magnetic Resonance Imaging; Female; Humans; Infarction, Middle Cerebral Artery; International Normalized Ratio; Logistic Models; Magnetic Resonance Angiography; Male; Multivariate Analysis; Prothrombin Time; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Severity of Illness Index; Stroke; Thiazoles; Warfarin

2018
Efficacy and Safety of Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation Patients With Impaired Liver Function: A Retrospective Cohort Study.
    Journal of the American Heart Association, 2018, 08-07, Volume: 7, Issue:15

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Cohort Studies; Dabigatran; Factor Xa Inhibitors; Female; Gastrointestinal Hemorrhage; Hemorrhage; Hepatic Insufficiency; Humans; Male; Proportional Hazards Models; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stroke; Thiazoles; Thromboembolism; Warfarin

2018
    Lakartidningen, 2018, 12-04, Volume: 115

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Factor Xa Inhibitors; Humans; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Stroke; Thiazoles; Warfarin

2018
Higher Incidence of Ischemic Stroke in Patients Taking Novel Oral Anticoagulants.
    Stroke, 2018, Volume: 49, Issue:12

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Brain Ischemia; Cohort Studies; Dabigatran; Female; Humans; Incidence; Intracranial Hemorrhages; Male; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stroke; Thiazoles; Warfarin

2018
Anticoagulation Therapy for Atrial Fibrillation in Patients With Alzheimer's Disease.
    Stroke, 2018, Volume: 49, Issue:12

    Topics: Aged; Alzheimer Disease; Anticoagulants; Atrial Fibrillation; Cost-Benefit Analysis; Dabigatran; Disease Progression; Health Care Costs; Humans; Pyrazoles; Pyridines; Pyridones; Quality-Adjusted Life Years; Rivaroxaban; Stroke; Thiazoles; Warfarin

2018
Hemorrhagic risk and intracranial complications in patients with minor head injury (MHI) taking different oral anticoagulants.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:9

    Topics: Aged; Aged, 80 and over; Anticoagulants; Craniocerebral Trauma; Dabigatran; Female; Humans; Intracranial Hemorrhages; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Risk; Rivaroxaban; Thiazoles; Vitamin K; Warfarin

2019
Resolution of left ventricular thrombus by edoxaban after failed treatment with warfarin overdose: A case report.
    Medicine, 2019, Volume: 98, Issue:2

    Topics: Adult; Anticoagulants; Brain Ischemia; Heart Failure; Heart Ventricles; Humans; Male; Pyridines; Retreatment; Stroke; Thiazoles; Thrombosis; Warfarin

2019
Formulating a single thioether-bridged oleate prodrug into a self-nanoemulsifying drug delivery system to facilitate oral absorption of docetaxel.
    Biomaterials science, 2019, Feb-26, Volume: 7, Issue:3

    Topics: Administration, Oral; Animals; Coumarins; Docetaxel; Drug Carriers; Drug Liberation; Emulsions; Intestinal Mucosa; Intestines; Mice; Oleic Acid; Particle Size; Prodrugs; Rats; Rats, Sprague-Dawley; Solubility; Sulfides; Thiazoles

2019
Tumor recognition of peanut agglutinin-immobilized fluorescent nanospheres in biopsied human tissues.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 136

    Topics: Animals; Colon; Colorectal Neoplasms; Coumarins; Female; Fluorescent Dyes; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanospheres; Peanut Agglutinin; Thiazoles

2019
Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Bioorganic chemistry, 2019, Volume: 85

    Topics: Antineoplastic Agents; Apoptosis; Caspase 7; Caspase 9; Catalytic Domain; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Quantitative Structure-Activity Relationship; Thiazoles; Vascular Endothelial Growth Factor Receptor-2

2019
Expansion of Two-dimension Electrospun Nanofiber Mats into Three-dimension Scaffolds.
    Journal of visualized experiments : JoVE, 2019, 01-07, Issue:143

    Topics: Animals; Carbon Dioxide; Coumarins; Nanofibers; Polyesters; Porosity; Rats, Sprague-Dawley; Thiazoles; Tissue Engineering; Tissue Scaffolds

2019
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies.
    Bioorganic chemistry, 2019, Volume: 86

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Coumarins; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Hydrazones; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Quantitative Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured

2019
Edoxaban (Lixiana°).
    Prescrire international, 2017, Volume: 26, Issue:178

    Topics: Anticoagulants; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Factor Xa Inhibitors; Hemorrhage; Humans; International Normalized Ratio; Pulmonary Embolism; Pyridines; Stroke; Thiazoles; Venous Thrombosis; Warfarin

2017
Stroke prevention in atrial fibrillation: Closing the gap.
    American heart journal, 2019, Volume: 210

    Topics: Administration, Oral; Anticoagulants; Aspirin; Atrial Fibrillation; Dabigatran; Health Services Misuse; Hemorrhage; Humans; International Normalized Ratio; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Septal Occluder Device; Stroke; Thiazoles; Warfarin

2019
Synthesis and Biological Evaluation of Novel Heterocyclic Imines Linked Coumarin- Thiazole Hybrids as Anticancer Agents.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:4

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Imines; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Thiazoles

2019
Direct Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation: Update and Periprocedural Management.
    Critical care nurse, 2019, Volume: 39, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Critical Care Nursing; Dabigatran; Female; Humans; Male; Middle Aged; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2019
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Computer Simulation; Coumarins; Lethal Dose 50; Mice; Quinolines; Structure-Activity Relationship; Thiazoles

2019
The evolving obesity paradigm story: from heart failure to atrial fibrillation.
    European heart journal, 2019, 05-14, Volume: 40, Issue:19

    Topics: Atrial Fibrillation; Body Mass Index; Heart Failure; Humans; Obesity; Pyridines; Thiazoles; Warfarin

2019
Surface-Modified Melphalan Nanoparticles for Intravitreal Chemotherapy of Retinoblastoma.
    Investigative ophthalmology & visual science, 2019, 04-01, Volume: 60, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Coumarins; Drug Delivery Systems; Flow Cytometry; Humans; Intravitreal Injections; Melphalan; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Retinal Neoplasms; Retinoblastoma; Thiazoles; Tumor Cells, Cultured

2019
EGFP-EGF1-conjugated poly(lactic-co-glycolic acid) nanoparticles, a new diagnostic tool and drug carrier for atherosclerosis.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Animals; Aorta; Atherosclerosis; Coumarins; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Fluorescence; Green Fluorescent Proteins; Humans; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nanoparticles; Particle Size; Peptide Elongation Factor G; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles

2019
Effectiveness and Safety of Four Direct Oral Anticoagulants in Asian Patients With Nonvalvular Atrial Fibrillation.
    Chest, 2019, Volume: 156, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Asian People; Atrial Fibrillation; Dabigatran; Databases, Factual; Female; Hemorrhage; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stroke; Taiwan; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2019
Preparation, optimization and cellular uptake study of tanshinone I nanoemulsion modified with lactoferrin for brain drug delivery.
    Pharmaceutical development and technology, 2019, Volume: 24, Issue:8

    Topics: Abietanes; Animals; Biological Availability; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Coumarins; Drug Carriers; Drug Delivery Systems; Emulsions; Lactoferrin; Mice; Nanoparticles; Particle Size; Permeability; Polyethylene Glycols; Solubility; Thiazoles; Tissue Distribution

2019
Spatio-temporal control on the delivery of triamcinolone acetonide using polymeric nanoparticles reduces steroid induced cataract.
    International journal of pharmaceutics, 2019, Sep-10, Volume: 568

    Topics: Administration, Ophthalmic; Animals; Biological Availability; Cadherins; Cataract; Coumarins; Diabetes Mellitus, Experimental; Drug Delivery Systems; Drug Liberation; Eye; Glucocorticoids; Male; Mice, Inbred C57BL; Poloxamer; Polyesters; Rats, Sprague-Dawley; Thiazoles; Triamcinolone Acetonide

2019
DOACs in Patients With Atrial Fibrillation and Liver Disease: Time to Expand the Safety Zone?
    Journal of the American College of Cardiology, 2019, 07-16, Volume: 74, Issue:2

    Topics: Atrial Fibrillation; Humans; Liver Diseases; Pyridines; Thiazoles; Warfarin

2019
Rapamycin loaded TPGS-Lecithins-Zein nanoparticles based on core-shell structure for oral drug administration.
    International journal of pharmaceutics, 2019, Sep-10, Volume: 568

    Topics: Administration, Oral; Animals; Caco-2 Cells; Cell Survival; Coumarins; Drug Carriers; Drug Liberation; Humans; Intestinal Absorption; Lecithins; Male; Nanoparticles; Rats, Sprague-Dawley; Sirolimus; Thiazoles; Vitamin E; Zein

2019
Self microemulsifying drug delivery system of lurasidone hydrochloride for enhanced oral bioavailability by lymphatic targeting: In vitro, Caco-2 cell line and in vivo evaluation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Oct-01, Volume: 138

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Coumarins; Drug Delivery Systems; Emulsions; Female; Humans; Lipids; Lurasidone Hydrochloride; Permeability; Rats; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Suspensions; Thiazoles

2019
Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase.
    Bioorganic chemistry, 2019, Volume: 91

    Topics: Alkaline Phosphatase; Animals; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; COS Cells; Coumarins; Drug Design; Enzyme Inhibitors; GPI-Linked Proteins; Humans; Hydrazones; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Thiazoles

2019
Ce6-C6-TPZ co-loaded albumin nanoparticles for synergistic combined PDT-chemotherapy of cancer.
    Journal of materials chemistry. B, 2019, 10-14, Volume: 7, Issue:38

    Topics: Animals; Cattle; Cell Line, Tumor; Cell Survival; Chlorophyllides; Coumarins; Humans; Light; Liver; Mice; Microscopy, Confocal; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Porphyrins; Serum Albumin, Bovine; Thiazoles; Tirapazamine; Transplantation, Homologous

2019
Whole-Eye Perfusion Model for Screening of the Ocular Formulations via Confocal Laser Scanning Microscopy.
    AAPS PharmSciTech, 2019, Sep-12, Volume: 20, Issue:7

    Topics: Administration, Ophthalmic; Animals; Coumarins; Drug Compounding; Drug Delivery Systems; Female; Micelles; Microscopy, Confocal; Perfusion; Rabbits; Swine; Thiazoles

2019
Exploring biological efficacy of coumarin clubbed thiazolo[3,2-b][1,2,4]triazoles as efficient inhibitors of urease: A biochemical and in silico approach.
    International journal of biological macromolecules, 2020, Jan-01, Volume: 142

    Topics: Binding Sites; Catalytic Domain; Coumarins; Enzyme Inhibitors; Models, Molecular; Molecular Structure; Protein Binding; Structure-Activity Relationship; Thiazoles; Triazoles; Urease

2020
Interface-Enrichment-Induced Instability and Drug-Loading-Enhanced Stability in Inhalable Delivery of Supramolecular Filaments.
    ACS nano, 2019, 11-26, Volume: 13, Issue:11

    Topics: Administration, Inhalation; Aerosols; Antineoplastic Agents, Phytogenic; Coumarins; Drug Delivery Systems; Drug Stability; Humans; Lung Diseases; Lung Neoplasms; Macromolecular Substances; Nanostructures; Paclitaxel; Particle Size; Peptides; Small Molecule Libraries; Surface Properties; Thiazoles

2019
Efficacy and safety of edoxaban compared with warfarin according to the burden of diseases in patients with atrial fibrillation: insights from the ENGAGE AF-TIMI 48 trial.
    European heart journal. Cardiovascular pharmacotherapy, 2020, 07-01, Volume: 6, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Comorbidity; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Stroke; Thiazoles; Thromboembolism; Time Factors; Treatment Outcome; Warfarin

2020
Anticoagulants in Atrial Fibrillation and Liver Disease.
    Journal of the American College of Cardiology, 2019, 11-12, Volume: 74, Issue:19

    Topics: Anticoagulants; Atrial Fibrillation; Humans; Liver Diseases; Pyridines; Thiazoles; Warfarin

2019
Development of novel optical pH sensors based on coumarin 6 and nile blue A encapsulated in resin particles and specific support materials.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 107

    Topics: Actinobacteria; Color; Coumarins; Fermentation; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Oxazines; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiazoles; Triazines; Urinalysis

2020
Effects of the molecular weight and molar ratio of poly(2-ethyl-2-oxazoline)-based lipid on the pH sensitivity, stability, and antitumor efficacy of liposomes.
    Drug development and industrial pharmacy, 2020, Volume: 46, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Coumarins; Drug Delivery Systems; Drug Liberation; Endosomes; Formates; Humans; Hydrogen-Ion Concentration; Lipids; Liposomes; Male; Mice; Molecular Weight; Polyamines; Polyethylene Glycols; Rats; Rats, Wistar; Thiazoles

2020
Comparison of Traumatic Intracranial Hemorrhage Expansion and Outcomes Among Patients on Direct Oral Anticoagulants Versus Vitamin k Antagonists.
    Neurocritical care, 2020, Volume: 32, Issue:2

    Topics: Accidental Falls; Aged; Aged, 80 and over; Anticoagulants; Antifibrinolytic Agents; Antithrombins; Blood Coagulation Factors; Coagulants; Dabigatran; Disease Progression; Factor Xa Inhibitors; Female; Glasgow Outcome Scale; Humans; Intracranial Hemorrhage, Traumatic; Length of Stay; Male; Middle Aged; Mortality; Neurosurgical Procedures; Plasma; Platelet Transfusion; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Thiazoles; Vitamin K; Warfarin

2020
Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins.
    Scientific reports, 2020, 02-19, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Cisplatin; Colorectal Neoplasms; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Energy Metabolism; G1 Phase; Glucose; HCT116 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; Reactive Oxygen Species; Thiazoles

2020
Effects of edoxaban and warfarin on vascular remodeling: Atherosclerotic plaque progression and collateral artery growth.
    Vascular pharmacology, 2020, Volume: 127

    Topics: Animals; Anticoagulants; Atherosclerosis; Collateral Circulation; Disease Models, Animal; Factor Xa Inhibitors; Fibrosis; Hindlimb; Ischemia; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Skeletal; Neovascularization, Physiologic; Plaque, Atherosclerotic; Pyridines; Thiazoles; Vascular Remodeling; Warfarin

2020
Comparing TEE- vs Non-TEE-guided cardioversion of atrial fibrillation: The ENSURE-AF trial.
    European journal of clinical investigation, 2020, Volume: 50, Issue:5

    Topics: Aged; Anticoagulants; Atrial Appendage; Atrial Fibrillation; Clinical Decision-Making; Duration of Therapy; Echocardiography, Transesophageal; Electric Countershock; Enoxaparin; Female; Heart Diseases; Humans; International Normalized Ratio; Male; Middle Aged; Pyridines; Randomized Controlled Trials as Topic; Stroke; Thiazoles; Thrombosis; Warfarin

2020
Tumor-targeting peptide functionalized PEG-PLA micelles for efficient drug delivery.
    Biomaterials science, 2020, Apr-15, Volume: 8, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Coumarins; Drug Delivery Systems; Drug Liberation; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Inbred ICR; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Spheroids, Cellular; Thiazoles; Tumor Burden

2020
Sonochemical fabrication of magnetic reduction-responsive alginate-based microcapsules for drug delivery.
    International journal of biological macromolecules, 2020, Jul-15, Volume: 155

    Topics: A549 Cells; Alginates; Capsules; Coumarins; Drug Carriers; Drug Liberation; HeLa Cells; Humans; Magnetite Nanoparticles; Oleic Acid; Thiazoles

2020
Management of antithrombotic therapy in gray areas of venous thromboembolism: a Delphi consensus panel.
    Internal and emergency medicine, 2020, Volume: 15, Issue:7

    Topics: Administration, Oral; Delphi Technique; Factor Xa Inhibitors; Female; Fibrin Fibrinogen Degradation Products; Fibrinolytic Agents; Humans; Male; Pyridines; Thiazoles; Venous Thromboembolism; Warfarin

2020
Trends in anticoagulant prescribing: a review of local policies in English primary care.
    BMC health services research, 2020, Apr-03, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Drug Utilization; England; Female; Humans; Male; Practice Patterns, Physicians'; Primary Health Care; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; State Medicine; Stroke; Thiazoles; Warfarin

2020
Current clinician perspective on non-vitamin K antagonist oral anticoagulant use in challenging clinical cases.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2020, Volume: 48, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Cardiologists; Clinical Trials, Phase III as Topic; Consensus; Dabigatran; Disease Management; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Female; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Pyridones; Randomized Controlled Trials as Topic; Rivaroxaban; Stroke; Thiazoles; Vitamin K; Warfarin

2020
Safety and effectiveness of non-vitamin K oral anticoagulants versus warfarin in real-world patients with non-valvular atrial fibrillation: a retrospective analysis of contemporary Japanese administrative claims data.
    Open heart, 2020, Volume: 7, Issue:1

    Topics: Administration, Oral; Administrative Claims, Healthcare; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Atrial Fibrillation; Dabigatran; Electronic Health Records; Female; Hemorrhage; Humans; Japan; Male; Middle Aged; Patient Safety; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Risk Assessment; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Time Factors; Treatment Outcome; Vitamin K; Warfarin

2020
Site-specific delivery of a natural chemotherapeutic agent to human lung cancer cells using biotinylated 2D rGO nanocarriers.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 112

    Topics: A549 Cells; Antineoplastic Agents; Biotinylation; Cell Survival; Coumarins; Drug Carriers; Endocytosis; Gallic Acid; Graphite; Humans; Lung Neoplasms; Microscopy, Fluorescence; Nanostructures; Sonication; Thiazoles

2020
Novel coumarin-thiazolyl ester derivatives as potential DNA gyrase Inhibitors: Design, synthesis, and antibacterial activity.
    Bioorganic chemistry, 2020, Volume: 100

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Coumarins; Drug Design; Esters; Humans; Molecular Docking Simulation; Thiazoles; Topoisomerase II Inhibitors

2020
Quantitative Volumetric Comparison of Direct Oral Anticoagulant and Vitamin K Antagonist Treatment for Pulmonary Thrombus Reduction During the Acute Phase in Symptomatic Patients.
    The American journal of the medical sciences, 2020, Volume: 360, Issue:2

    Topics: Aged; alpha-2-Antiplasmin; Anticoagulants; Antithrombin III; Contrast Media; Factor Xa Inhibitors; Female; Fibrin Fibrinogen Degradation Products; Fibrinolysin; Heparin; Humans; International Normalized Ratio; Length of Stay; Male; Middle Aged; Peptide Hydrolases; Prothrombin Time; Pulmonary Artery; Pulmonary Embolism; Pyridines; Retrospective Studies; Thiazoles; Tomography, X-Ray Computed; Treatment Outcome; Warfarin

2020
Influence of anticoagulants on the risk of delayed bleeding after gastric endoscopic submucosal dissection: a multicenter retrospective study.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Anticoagulants; Dabigatran; Endoscopic Mucosal Resection; Female; Humans; Japan; Male; Middle Aged; Postoperative Complications; Postoperative Hemorrhage; Pyrazoles; Pyridines; Pyridones; Retrospective Studies; Rivaroxaban; Stomach; Stomach Neoplasms; Thiazoles; Thromboembolism; Warfarin

2021
Recurrent venous thromboembolism during anticoagulation with edoxaban or warfarin: A post hoc analysis of the Hokusai-VTE trial.
    Thrombosis research, 2020, Volume: 195

    Topics: Anticoagulants; Factor Xa Inhibitors; Humans; Male; Pyridines; Thiazoles; Venous Thromboembolism; Warfarin

2020
Development of a Ratiometric Fluorescent Glucose Sensor Using an Oxygen-Sensing Membrane Immobilized with Glucose Oxidase for the Detection of Glucose in Tears.
    Biosensors, 2020, Jul-29, Volume: 10, Issue:8

    Topics: Biosensing Techniques; Coumarins; Fluorescent Dyes; Glucose; Glucose Oxidase; Tears; Thiazoles

2020
Cost-effectiveness of edoxaban vs low-molecular-weight heparin and warfarin for cancer-associated thrombosis in Brazil.
    Thrombosis research, 2020, Volume: 196

    Topics: Anticoagulants; Brazil; Cost-Benefit Analysis; Heparin, Low-Molecular-Weight; Humans; Neoplasms; Pyridines; Quality-Adjusted Life Years; Thiazoles; Thrombosis; Warfarin

2020
Non-vitamin K antagonist oral anticoagulants in very elderly east Asians with atrial fibrillation: A nationwide population-based study.
    American heart journal, 2020, Volume: 229

    Topics: Aged, 80 and over; Atrial Fibrillation; Brain Ischemia; Databases, Factual; Factor Xa Inhibitors; Female; Gastrointestinal Hemorrhage; Humans; Intracranial Hemorrhages; Male; Pyrazoles; Pyridines; Pyridones; Republic of Korea; Stroke; Thiazoles; Vitamin K; Warfarin

2020
Comparisons of Edoxaban Versus Warfarin on Levels of Plasma Prothrombin Fragment in Patients With Nonvalvular Atrial Fibrillation.
    The American journal of cardiology, 2020, 12-01, Volume: 136

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Female; Humans; Male; Peptide Fragments; Prospective Studies; Prothrombin; Pyridines; Stroke; Thiazoles; Warfarin

2020
Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity.
    Bioorganic chemistry, 2020, Volume: 104

    Topics: Adenosine Triphosphatases; Anti-Bacterial Agents; Bordetella pertussis; Cell Line; Coumarins; DNA Gyrase; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Mycoplasma pneumoniae; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors

2020
Outcomes of long-term anticoagulant treatment for the secondary prophylaxis of splanchnic venous thrombosis.
    European journal of clinical investigation, 2021, Volume: 51, Issue:1

    Topics: Acenocoumarol; Adult; Anticoagulants; Budd-Chiari Syndrome; Duration of Therapy; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Mesenteric Ischemia; Middle Aged; Portal Vein; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Secondary Prevention; Thiazoles; Venous Thrombosis; Warfarin

2021
Switching warfarin patients to a direct oral anticoagulant during the Coronavirus Disease-19 pandemic.
    Thrombosis research, 2021, Volume: 197

    Topics: Administration, Oral; Anticoagulants; Counseling; COVID-19; Drug Monitoring; Drug Substitution; Hospitals, University; Humans; Informed Consent; London; Pandemics; Patient Acceptance of Health Care; Patient Education as Topic; Pyridines; Quarantine; Rivaroxaban; SARS-CoV-2; Telemedicine; Tertiary Care Centers; Thiazoles; Thrombophilia; Warfarin

2021
Non-warfarin oral anticoagulant copayments and adherence in atrial fibrillation: A population-based cohort study.
    American heart journal, 2021, Volume: 233

    Topics: Anticoagulants; Antithrombins; Atrial Fibrillation; Cohort Studies; Dabigatran; Databases, Factual; Deductibles and Coinsurance; Drug Costs; Factor Xa Inhibitors; Female; Humans; Male; Medicare Part C; Medication Adherence; Middle Aged; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Sample Size; Stroke; Thiazoles; United States; Warfarin

2021
Defective transition metal hydroxide-based nanoagents with hypoxia relief for photothermal-enhanced photodynamic therapy.
    Journal of materials chemistry. B, 2021, 01-28, Volume: 9, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Proliferation; Cell Survival; Coumarins; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Hydroxides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Nanoparticles; Particle Size; Photochemotherapy; Photosensitizing Agents; Silicon Dioxide; Surface Properties; Thiazoles; Transition Elements; Tumor Cells, Cultured

2021
FRET imaging revealed that nanocrystals enhanced drug oral absorption by dissolution rather than endocytosis: A case study of coumarin 6.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 04-10, Volume: 332

    Topics: Administration, Oral; Animals; Biological Availability; Coumarins; Endocytosis; Fluorescence Resonance Energy Transfer; Nanoparticles; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Solubility; Thiazoles; Tissue Distribution

2021
Regression of Melanoma Following Intravenous Injection of Plumbagin Entrapped in Transferrin-Conjugated, Lipid-Polymer Hybrid Nanoparticles.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Liberation; Endocytosis; Female; Humans; Injections, Intravenous; Lipids; Melanoma, Experimental; Mice, Inbred BALB C; Nanoparticles; Naphthoquinones; Polymers; Skin Neoplasms; Thiazoles; Transferrin

2021
Use of oral anticoagulants in patients with valvular atrial fibrillation: findings from the NCDR PINNACLE Registry.
    American heart journal, 2021, Volume: 240

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Dabigatran; Female; Humans; Male; Practice Patterns, Physicians'; Pyrazoles; Pyridines; Pyridones; Registries; Risk Factors; Rivaroxaban; Stroke; Thiazoles; Warfarin

2021
Sonochemical preparation of folate-decorated reductive-responsive carboxymethylcellulose-based nanocapsules for targeted drug delivery.
    Carbohydrate polymers, 2021, Aug-15, Volume: 266

    Topics: Carboxymethylcellulose Sodium; Cell Line, Tumor; Cell Survival; Coumarins; Drug Carriers; Drug Liberation; Folic Acid; Humans; Nanocapsules; Thiazoles; Ultrasonic Waves

2021
Unsolved issues of The Efficacy and Safety of Edoxaban.
    Anatolian journal of cardiology, 2021, Volume: 25, Issue:6

    Topics: Atrial Fibrillation; Humans; Pyridines; Thiazoles; Warfarin

2021
Bleeding complications in patients with gastrointestinal cancer and atrial fibrillation treated with oral anticoagulants.
    Cancer medicine, 2021, Volume: 10, Issue:13

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Cohort Studies; Confidence Intervals; Dabigatran; Denmark; Factor Xa Inhibitors; Female; Gastrointestinal Neoplasms; Hemorrhage; Humans; Male; Proportional Hazards Models; Pyrazoles; Pyridines; Pyridones; Rivaroxaban; Stroke; Thiazoles; Warfarin

2021
Novel chalcone-conjugated, multi-flexible end-group coumarin thiazole hybrids as potential antibacterial repressors against methicillin-resistant Staphylococcus aureus.
    European journal of medicinal chemistry, 2021, Oct-15, Volume: 222

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Chalcones; Coumarins; Dose-Response Relationship, Drug; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles

2021
Comparative effectiveness and safety of edoxaban versus warfarin in patients with atrial fibrillation: A nationwide cohort study.
    International journal of stroke : official journal of the International Stroke Society, 2022, Volume: 17, Issue:5

    Topics: Aged; Anticoagulants; Atrial Fibrillation; Cohort Studies; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Pyridines; Stroke; Thiazoles; Thromboembolism; Treatment Outcome; Warfarin

2022
Ratiometric Fluorescent Biosensors for Glucose and Lactate Using an Oxygen-Sensing Membrane.
    Biosensors, 2021, Jun-25, Volume: 11, Issue:7

    Topics: Biosensing Techniques; Catalysis; Coumarins; Fluorescence; Fluorescent Dyes; Glucose; Glucose Oxidase; Humans; Lactic Acid; Limit of Detection; Oxygen; Platinum; Porphyrins; Spectrometry, Fluorescence; Thiazoles

2021
Novel Coumarin-Thiadiazole Hybrids and Their Cu(II) and Zn(II) Complexes as Potential Antimicrobial Agents and Acetylcholinesterase Inhibitors.
    International journal of molecular sciences, 2021, Sep-08, Volume: 22, Issue:18

    Topics: Acetylcholinesterase; Anti-Bacterial Agents; Anti-Infective Agents; Cholinesterase Inhibitors; Copper; Coumarins; Crystallography, X-Ray; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Metals; Microbial Sensitivity Tests; Neurodegenerative Diseases; Pseudomonas aeruginosa; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Staphylococcus aureus; Staphylococcus epidermidis; Thiadiazoles; Thiazoles; Zinc

2021
Anti-proliferative, c-Met Inhibitions, and PAINS Evaluations of New Thiophene, Thiazole, Coumarin, Pyran, and Pyridine Derivatives.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Cyclohexanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Pyrans; Pyridines; Structure-Activity Relationship; Thiazoles; Thiophenes

2022
Hip fractures risks in edoxaban versus warfarin users: A propensity score-matched population-based cohort study with competing risk analyses.
    Bone, 2022, Volume: 156

    Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Cohort Studies; Female; Hip Fractures; Humans; Male; Middle Aged; Propensity Score; Pyridines; Retrospective Studies; Risk Assessment; Stroke; Thiazoles; Warfarin

2022
Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents.
    Bioorganic chemistry, 2022, Volume: 124

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Coumarins; Mammals; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Skeleton; Thiazoles

2022
Synthesis and biological evaluation of coumarin-thiazole hybrids as selective carbonic anhydrase IX and XII inhibitors.
    Archiv der Pharmazie, 2022, Volume: 355, Issue:12

    Topics: Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Coumarins; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles

2022
Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety.
    Scientific reports, 2023, 06-19, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Coumarins; Microbial Sensitivity Tests; Molecular Structure; Pyrazoles; Pyridines; Thiazoles

2023