thiazoles has been researched along with verapamil in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (17.65) | 18.7374 |
| 1990's | 20 (39.22) | 18.2507 |
| 2000's | 13 (25.49) | 29.6817 |
| 2010's | 8 (15.69) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Belov, L; Davey, MW; Davey, RA; Kidman, AD; Marks, DC | 1 |
| Glossmann, H; Knaus, HG; Staudinger, R | 1 |
| Borgers, M; Thoné, F; Vandeplassche, G | 1 |
| Mutafova-Yambolieva, V; Staneva-Stoytcheva, D; Todorov, S; Vassilev, P | 1 |
| Ford, JM; Hait, WN; Yang, JM | 1 |
| Iso, T; Miyawaki, N; Nishimura, K; Yamauchi, H | 1 |
| Bazill, GW; Dexter, TM | 1 |
| Peters, T; Scheufler, E | 1 |
| Borgers, M; De Clerck, F; Vandewiele, R; Ver Donck, L; Verellen, G | 1 |
| Eliason, JF; Kaufmann, F; Ramuz, H | 1 |
| Coley, HM; Twentyman, PR; Workman, P | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Agabiti-Rosei, E; Muiesan, G | 1 |
| Hofsli, E; Nissen-Meyer, J | 1 |
| Sheng, BH; Yang, XM; Zhao, DH | 1 |
| Koch, P; Nebel, U; Peters, T; Wermelskirchen, D; Wilffert, B; Wilhelm, D | 1 |
| Fischli, W; Hengartner, U; Holck, M | 1 |
| Ito, K; Kanazawa, T; Morita, T; Nose, T | 1 |
| Ito, K; Morita, T; Nose, T; Sukamoto, T; Yoshidomi, M | 1 |
| Bado, A; Braquet, P; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I; Tarrade, T | 1 |
| Kageyama, M; Taira, N; Yanagisawa, T | 1 |
| Park, SR; Ryu, GH; Suh, CK | 1 |
| De Clerck, F; Lu, HR | 1 |
| De Clerck, F; Lu, HR; Remeysen, P | 1 |
| Guttmann, I; Mozes, A; Scheufler, E; Wilffert, B | 1 |
| Ishibashi, M; Kobayashi, J; Kondo, K; Ohizumi, Y; Park, YH; Rho, MC; Sasaki, S | 1 |
| Dai, DZ; De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Yang, P | 1 |
| Asano, M; Hazama, H; Imuta, H; Iwasawa, K; Kawakami, Y; Morita, T; Nakajima, T; Nakamura, F; Okuda, Y; Omata, M; Oonuma, H; Suzuki, J; Suzuki, S | 1 |
| Gros, P; Julien, M; Kaback, RH; Kajiji, S | 1 |
| Diamond, RH; Forman, LM; Simmons, DA | 1 |
| Brodmann, M; Haiden, U; Schwarzl, I; Stark, G; Stark, U; Tritthart, HA | 1 |
| Atherton, K; Campbell, FC; Daly, AK; Harbottle, A | 1 |
| Buchmann, B; Bunte, T; Hoffmann, J; Klar, U; Lichtner, RB; Rotgeri, A; Schwede, W; Skuballa, W | 1 |
| Fu, LW; Lin, GY; Pan, QC | 1 |
| Barhoumi, R; Burghardt, RC; Kochevar, DT; Mealey, KL; Safe, S | 1 |
| Honkakoski, P; Urtti, A; Vellonen, KS | 1 |
| Frigieri, A; Huet, H; Huynh-Delerme, C; Kolf-Clauw, M; Noël, L | 1 |
| Ban, JY; Lee, BY; Seong, YH | 1 |
| He, L; Ji, BS; Liu, GQ | 1 |
| Kurttila, T; Myllynen, P; Vähäkangas, K; Vaskivuo, L | 1 |
| Boellaard, R; Lammertsma, AA; Lubberink, M; Mourik, JE; Schuitemaker, A; Tolboom, N; van Berckel, BN | 1 |
| Cai, Z; Cui, FY; Gong, DQ; He, G; Hou, SX; Lei, XJ; Song, XR; Wei, YQ; Xiong, SJ; Zheng, Y | 1 |
| Kito, Y; Suzuki, H | 1 |
| He, G; He, ZY; Hou, SX; Li, JM; Li, SZ; Luo, X; Luo, YF; Song, XR; Wei, YQ; Yang, L; Yu, S; Zheng, Y | 1 |
| Iwasaki, R; Satoh, E | 1 |
| Hu, J; Huang, K; Li, X; Li, Y | 1 |
| Covell, DG | 1 |
| Fujiwara, D; Imano, M; Itoh, T; Komai, M; Mashimo, K; Mukai, J; Nishida, S; Ogawa, N; Sakaguchi, K; Sakamoto, K; Satou, T; Shimaoka, H; Takeda, T; Tsubaki, M | 1 |
| Azzali, E; Cabassi, CS; Costantino, G; Flisi, S; Kaushik, A; Lamichhane, G; Machado, D; Pieroni, M; Vacondio, F; Viveiros, M | 1 |
| Dang, NL; Hughes, TB; Miller, GP; Swamidass, SJ | 1 |
| Bix, GJ; Fraser, JF; Gorman, A; Maniskas, ME; Roberts, JM | 1 |
1 trial(s) available for thiazoles and verapamil
| Article | Year |
|---|---|
Etozolin monotherapy and combination with verapamil in essential hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Multicenter Studies as Topic; Thiazoles; Verapamil | 1989 |
50 other study(ies) available for thiazoles and verapamil
| Article | Year |
|---|---|
The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Epirubicin; Humans; Membrane Glycoproteins; Tetrazolium Salts; Thiazoles; Trypan Blue; Verapamil; Vinblastine | 1992 |
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil | 1991 |
Protective effects of R 56 865 against ischemic damage in the isolated rabbit heart.
Topics: Animals; Benzothiazoles; Calcium; Calcium Channels; Cell Death; Coronary Disease; Female; Hemodynamics; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Perfusion; Piperidines; Rabbits; Subcellular Fractions; Thiazoles; Verapamil | 1991 |
Involvement of calcium ions in the modulation of electrically-induced rat vas deferens contractions by histaminergic drugs.
Topics: Animals; Calcium; Cimetidine; Dimaprit; Diphenhydramine; Electric Stimulation; Histamine; In Vitro Techniques; Male; Muscle Contraction; Rats; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Thiourea; Vas Deferens; Verapamil | 1991 |
Effect of buthionine sulfoximine on toxicity of verapamil and doxorubicin to multidrug resistant cells and to mice.
Topics: Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Flupenthixol; Glutathione; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Verapamil | 1991 |
Tissue selectivity of the novel calcium antagonist sesamodil fumarate in isolated smooth muscles and cardiac muscles.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Swine; Thiazoles; Verapamil | 1990 |
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil | 1990 |
Phosphatidylserine monolayers as models for drug uptake into membranes and tissue.
Topics: Animals; Aorta; Benzothiazoles; Cell Membrane; Diltiazem; Erythrocyte Membrane; Flunarizine; Heart Atria; Humans; Lidocaine; Membranes, Artificial; Models, Biological; Nitrendipine; Pharmaceutical Preparations; Pharmacokinetics; Phosphatidylserines; Piperidines; Rats; Thiazoles; Verapamil | 1990 |
Class IV Ca2+ antagonists do not affect lipid peroxidation in singlet oxygen challenged cardiomyocytes.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Cell Separation; Cinnarizine; Diltiazem; Flunarizine; Lidoflazine; Lipid Peroxidation; Malondialdehyde; Myocardium; Nicardipine; Oxygen; Piperidines; Rats; Thiazoles; Verapamil | 1990 |
Human multi-drug-resistant cancer cells exhibit a high degree of selectivity for stereoisomers of verapamil and quinidine.
Topics: Cell Line; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; HeLa Cells; Humans; Neoplasms; Quinidine; Stereoisomerism; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 1990 |
Identification of anthracyclines and related agents that retain preferential activity over adriamycin in multidrug-resistant cell lines, and further resistance modification by verapamil and cyclosporin A.
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Small Cell; Cell Line; Coloring Agents; Cyclosporins; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 1989 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Effect of erythromycin and tumour necrosis factor on the drug resistance of multidrug-resistant cells: reversal of drug resistance by erythromycin.
Topics: Animals; Antineoplastic Agents; Coloring Agents; Dactinomycin; Doxorubicin; Drug Interactions; Drug Resistance; Drug Synergism; Erythromycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Verapamil | 1989 |
[Effects of thioproline on isolated guinea pig papillary muscles].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Chloride; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Thiazoles; Thiazolidines; Verapamil | 1986 |
Different effects of R 56865 and calcium entry blockers on K+- and noradrenaline-induced contractions and 45Ca uptake in rat aorta.
Topics: Animals; Aorta; Benzothiazoles; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Flunarizine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Piperidines; Potassium; Rats; Rats, Inbred Strains; Thiazoles; Verapamil | 1988 |
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil | 1984 |
Vasodilator mechanism of KB-944, a new calcium antagonist.
Topics: Adenosine; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Coronary Vessels; Diltiazem; Dogs; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium; Rabbits; Thiazoles; Vasodilator Agents; Verapamil | 1982 |
Antiarrhythmic effect of KB-944, a new calcium antagonist. A comparison with verapamil and diltiazem.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Epinephrine; Guinea Pigs; Male; Ouabain; Rats; Thiazoles; Verapamil | 1982 |
Platelet-activating factor stimulates gastric acid secretion in isolated rabbit gastric glands.
Topics: Aminopyrine; Animals; Azepines; Biological Transport; Calcium; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Famotidine; Fluorescent Dyes; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rabbits; Thiazoles; Thienopyridines; Triazoles; Verapamil | 1995 |
Effects of semotiadil fumarate, a novel Ca2+ antagonist, on cytosolic Ca2+ level and force of contraction in porcine coronary arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Cytosol; Potassium Chloride; Radioligand Assay; Receptors, Histamine H1; Swine; Thiazoles; Vasoconstriction; Verapamil | 1995 |
Cardioprotective drugs decrease the Na+ background current.
Topics: Amiloride; Animals; Benzothiazoles; Guinea Pigs; Heart; Heart Arrest, Induced; Myocardium; Piperidines; Potassium; Sodium; Thiazoles; Verapamil | 1995 |
R 56 865, a Na+/Ca(2+)-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Benzothiazoles; Calcium; Dose-Response Relationship, Drug; Hemodynamics; Lidocaine; Male; Piperidines; Random Allocation; Rats; Rats, Wistar; Sodium; Sodium Channels; Tetrodotoxin; Thiazoles; Verapamil | 1993 |
Inhibition of Na+/Ca2+ overload with R 56,865 protects against cardiac arrhythmias elicited by ouabain in vivo in guinea-pigs.
Topics: Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Electrocardiography; Guinea Pigs; Heart Rate; Lidocaine; Male; Ouabain; Piperidines; Sodium; Tetrodotoxin; Thiazoles; Verapamil | 1993 |
R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzothiazoles; Calcium; Calcium Channel Blockers; Extracellular Space; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Piperidines; Potassium; Sodium; Thiazoles; Verapamil | 1995 |
The mode of rabbit platelet shape change and aggregation induced by theonezolide-A, a novel polyketide macrolide, isolated from the Okinawan marine sponge Theonella sp.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcium; Calcium Channel Blockers; Cell Size; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Isoflavones; Male; Oxazoles; Platelet Aggregation; Porifera; Protein-Tyrosine Kinases; Rabbits; Thiazoles; Verapamil | 1996 |
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
Topics: Amiloride; Anesthesia; Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Heart Rate; Lidocaine; Male; Myocardial Reperfusion Injury; Piperidines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Thiazoles; Verapamil | 1999 |
Troglitazone inhibits voltage-dependent calcium currents in guinea pig cardiac myocytes.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cardiotonic Agents; Chromans; Cyclic AMP; Electric Conductivity; Guinea Pigs; Hypoglycemic Agents; Isoproterenol; Kinetics; Myocardium; Nifedipine; Thiazoles; Thiazolidinediones; Troglitazone; Verapamil | 1999 |
Simple purification of highly active biotinylated P-glycoprotein: enantiomer-specific modulation of drug-stimulated ATPase activity.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biotinylation; Drug Resistance, Multiple; Enzyme Activators; Histidine; Humans; Klebsiella pneumoniae; Mice; Peptides; Pichia; Piperazines; Quinolines; Recombinant Fusion Proteins; Stereoisomerism; Thiazoles; Tumor Cells, Cultured; Verapamil; Vinblastine | 2000 |
Hepatic failure in a patient taking rosiglitazone.
Topics: Aged; Combined Modality Therapy; Coronary Disease; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypoglycemic Agents; Ischemia; Liver; Liver Failure; Male; Monitoring, Physiologic; Pravastatin; Rosiglitazone; Thiazoles; Thiazolidinediones; Verapamil | 2000 |
Efficacy of the novel calcium antagonist R(+)-semotiadil in limiting the ventricular rate during atrial flutter in isolated guinea pig hearts.
Topics: Animals; Atrial Flutter; Atrioventricular Node; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; In Vitro Techniques; Male; Thiazoles; Time Factors; Ventricular Function; Verapamil | 2000 |
Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Coloring Agents; Curcumin; Cytosol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Genetic Vectors; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Immunoblotting; Inhibitory Concentration 50; Isoenzymes; Liver; Multidrug Resistance-Associated Proteins; Phenotype; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection; Tumor Cells, Cultured; Verapamil | 2001 |
Subcellular distribution of epothilones in human tumor cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Division; Cell Line; Epothilones; Epoxy Compounds; Humans; Kinetics; Macrolides; Paclitaxel; Thiazoles; Tumor Cells, Cultured; Verapamil | 2001 |
[Compared study on Fura-2/AM assay and MTT assay for screening multidrug resistant modulators].
Topics: Bepridil; Breast Neoplasms; Calcium Channel Blockers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fura-2; Humans; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 1997 |
Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells.
Topics: Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Breast Neoplasms; Calcium Channel Blockers; Cell Survival; Doxycycline; Drug Interactions; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Immunoblotting; In Situ Hybridization; Lasers; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Verapamil | 2002 |
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cattle; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Humans; L-Lactate Dehydrogenase; Multidrug Resistance-Associated Proteins; Oxidation-Reduction; Propionates; Quinolines; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles; Verapamil | 2004 |
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium.
Topics: ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Blotting, Western; Caco-2 Cells; Cadmium Poisoning; Calcium Channel Blockers; Cell Survival; DNA; Drug Resistance, Multiple; Electrophoresis, Agar Gel; Fluoresceins; Fluorescent Dyes; Humans; L-Lactate Dehydrogenase; Neutral Red; Tetrazolium Salts; Thiazoles; Verapamil | 2005 |
Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Baclofen; Blotting, Western; Calcium; Calcium Channel Blockers; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; GABA Agonists; Glutamic Acid; Muscimol; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, GABA-A; Tetrazolium Salts; Thiazoles; Time Factors; Verapamil | 2005 |
Reversal of p-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
Topics: Amlodipine; Analysis of Variance; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Therapy; Flow Cytometry; Fluorescence; Humans; K562 Cells; Neoplasms; Rhodamine 123; Tetrazolium Salts; Thiazoles; Time Factors; Verapamil | 2005 |
DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Calcium Channel Blockers; Carcinogens; Cell Line, Tumor; Cell Survival; Cyclosporins; DNA Adducts; DNA Damage; Drug Synergism; Female; Humans; Probenecid; Renal Agents; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53; Verapamil | 2007 |
Image-derived input functions for PET brain studies.
Topics: Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Humans; Image Processing, Computer-Assisted; Isoquinolines; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Verapamil | 2009 |
Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2009 |
Properties of Rikkunshi-to (TJ-43)-induced relaxation of rat gastric fundus smooth muscles.
Topics: Animals; Apamin; Drugs, Chinese Herbal; Enprostil; Gastric Fundus; Hesperidin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Potassium; Pyrimidinones; Quinoxalines; Rats; Thiazoles; Verapamil | 2010 |
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2010 |
Experimental diabetes attenuates calcium mobilization and proliferative response in splenic lymphocytes from mice.
Topics: Animals; Blood Glucose; Body Weight; Calcium; Calcium Channels, L-Type; Concanavalin A; Diabetes Mellitus, Experimental; Fura-2; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Male; Mice; Spleen; Tetrazolium Salts; Thiazoles; Verapamil | 2011 |
Role of P-glycoprotein in intestinal absorption of FB2, a promising Abl/Src dual tyrosine kinase inhibitor.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Cell Line, Tumor; Humans; Intestinal Absorption; Intestinal Mucosa; Madin Darby Canine Kidney Cells; Male; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Rats; Rats, Sprague-Dawley; src-Family Kinases; Thiazoles; Verapamil | 2012 |
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil | 2012 |
By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bcl-2-Like Protein 11; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Dasatinib; Dexamethasone; Down-Regulation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Melphalan; Membrane Proteins; Multiple Myeloma; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyrimidines; src-Family Kinases; Survivin; Thiazoles; Up-Regulation; Verapamil | 2014 |
Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Drug Resistance, Multiple, Bacterial; Drug Stability; Ethidium; Humans; Isoxazoles; Macrophages; Membrane Transport Proteins; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Thiazoles; Thioridazine; Verapamil | 2017 |
Computationally Assessing the Bioactivation of Drugs by N-Dealkylation.
Topics: Aldehydes; Amines; Dealkylation; Humans; Indinavir; Liver; Microsomes, Liver; Models, Molecular; Molecular Structure; Piperacillin; Piperazines; Thiazoles; Verapamil | 2018 |
Intra-arterial combination therapy for experimental acute ischemic stroke.
Topics: Animals; Calcium Channel Blockers; Combined Modality Therapy; Infusions, Intra-Arterial; Ischemic Stroke; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Piperidines; Thiazoles; Treatment Outcome; Verapamil | 2022 |