thiazoles has been researched along with tyrosine in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (11.68) | 18.7374 |
| 1990's | 13 (9.49) | 18.2507 |
| 2000's | 72 (52.55) | 29.6817 |
| 2010's | 32 (23.36) | 24.3611 |
| 2020's | 4 (2.92) | 2.80 |
| Authors | Studies |
|---|---|
| Rudolph, FB; White, RH | 1 |
| Spenser, ID; White, RL | 1 |
| Bellion, E; Faust, JR; Kirkley, DH | 1 |
| Liu, J; Piotrowski, J; Slomiany, A; Slomiany, BL | 1 |
| d'Ischia, M; Havens, M; Napolitano, A; Prota, G; Tramposch, K | 1 |
| Kumaoka, H; Morisaki, M; Saiki, K; Tazuya, K; Yamada, K | 1 |
| Götz, HG | 1 |
| Huggins, CG; Sander, GE; West, DW | 1 |
| Moore, KE; Thornburg, JE | 1 |
| Estramareix, B; Therisod, M | 2 |
| Bahramian, MB; Middleton, RB | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Iwashima, A; Nose, Y | 1 |
| Fairwell, T; Lovins, RE | 1 |
| Boukma, SJ; Johnson, GA; Kim, EG | 1 |
| Berti, L; Häring, H; Kellerer, M; Kiehn, R; Kroder, G; Mosthaf, L; Tippmer, S | 1 |
| Bleasdale, JE; Jacob, CS; Sizer, KM; Smith, CL; Swanson, ML | 1 |
| Egawa, K; Hasegawa, M; Ide, R; Iwanishi, M; Kashiwagi, A; Kikkawa, R; Maegawa, H; Shigeta, Y; Ugi, S | 1 |
| Carstam, R; Hindemith, A; Odh, G; Paulson, J; Rorsman, H; Rosengren, E | 1 |
| Czajkowski, A; Piotrowski, J; Slomiany, A; Slomiany, BL; Yotsumoto, F | 1 |
| Becker, D; Knop, J; Kühn, U; van Brandwijk, R; Willemsen, J | 1 |
| Ischiropoulos, H; Thom, SR; Xu, YA | 1 |
| Ansorge, S; Faust, J; Kähne, T; Neubert, K | 1 |
| Blanchard, SG; Boswell, GE; Charifson, PS; Cobb, JE; Collins, JL; Gray-Nunez, Y; Henke, BR; Hull-Ryde, EA; Kazmierski, WM; Lake, DH; Leesnitzer, LM; Lehmann, J; Lenhard, JM; Orband-Miller, LA; Parks, DJ; Plunkett, KD; Tong, WQ | 1 |
| Adkison, K; Binz, JG; Blanchard, SG; Brown, HR; Brown, KK; Cobb, JE; Faison, W; Harrington, WW; Hashim, MA; Henke, BR; Kaldor, I; Kliewer, SA; Lehmann, JM; Lenhard, JM; Menius, JA; Mook, R; Noble, SA; Novak, PJ; Oliver, WO; Parks, DJ; Plunket, KD; Tong, WQ; Willson, TM | 1 |
| Cheng, XS; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, J; Shimokawa, H; Takeshita, A | 1 |
| Abas, L; Bogoyevitch, MA; Court, NW; Dhillon, A; Draper, KA; Ng, DC | 1 |
| Batignani, G; Bonacchi, A; Caligiuri, A; Caporale, R; Efsen, E; Gentilini, P; Laffi, G; Marra, F; Pastacaldi, S; Pinzani, M; Romanelli, RG | 1 |
| Brown, KK; Glass, CK; Li, AC; Palinski, W; Silvestre, MJ; Willson, TM | 1 |
| Arrieumerlou, C; Bismuth, G; Randriamampita, C; Trautmann, A | 1 |
| Buyukafsar, K; Martin, W; Nelli, S | 1 |
| Anai, M; Ando, K; Asano, T; Chiba, Y; Fujishiro, M; Fujita, T; Fukushima, Y; Inukai, K; Kikuchi, M; Ogihara, T; Onishi, Y; Ono, H; Sakoda, H; Sekine, N; Shojima, N | 1 |
| Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM | 1 |
| Brown, BK; Song, W | 1 |
| Duff, K; La Francois, J; Matsuoka, Y; Picciano, M | 1 |
| Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P | 1 |
| Knaggs, AR | 1 |
| Aoyagi, K; Kondo, S; Ohnishi, H; Ono, K; Takahashi, M; Yamamori, S | 1 |
| Hevener, AL; Janez, A; Olefsky, J; Reichart, D | 1 |
| Chatterjee, VK; Nugent, C; O'Rahilly, S; Prins, JB; Savage, D; Wentworth, JM; Whitehead, JP | 1 |
| Arjunan, P; Brown, AM; Furey, W; Guest, JR; Jordan, F; Nemeria, N; Yan, Y; Zhang, Z | 1 |
| Hsueh, WA; Kim, S; Kintscher, U; Kuroki, T; Law, RE; Liu, Z; Ohba, M; Schönthal, AH; Wakino, S; Yin, F | 1 |
| Auwerx, J; Bac, P; Blanchard, SG; Champy, MF; Desreumaux, P; Dubuquoy, L; Gelman, L; Leesnitzer, LM; Moras, D; Picard, F; Plunket, KD; Potier, N; Renaud, JP; Rocchi, S; Vamecq, J; Zeyer, D | 1 |
| Broussard, SR; Dantzer, R; Freund, GG; Johnson, RW; Kelley, KW; Strle, K; Venters, HD; Zhou, JH | 1 |
| Chikara, S; Fukuda, N; Hu, WY; Kanmatsuse, K; Kishioka, H; Nakayama, M; Teng, J | 1 |
| Chi, KH; Chio, CC; Huang, WC; Lin, WW; Wu, HM | 1 |
| Brosnan, CF; Dumitrescu-Ozimek, L; Feinstein, DL; Galea, E; Gavrilyuk, V; Heneka, MT; Landreth, GE; Pershadsingh, HA; Weinberg, G; Whitacre, CC | 1 |
| Corton, JC; Dohm, GL; Houmard, JA; Kraus, WE; Lang, DB; Li, S; MacLean, PS; Muoio, DM; Way, JM; Winegar, DA | 1 |
| McKeown-Longo, PJ; Zheng, M | 1 |
| Gonzalez, T; Grémeaux, T; Gual, P; Kanzaki, M; Le Marchand-Brustel, Y; Pessin, JE; Shigematsu, S; Tanti, JF | 1 |
| Clemetson, KJ; Navdaev, A | 1 |
| Brown, PA; Chatterjee, BE; Chatterjee, PK; Cuzzocrea, S; Mota-Filipe, H; Patel, NS; Serraino, I; Stewart, KN; Thiemermann, C | 1 |
| Jensen, BA; Mann, KK; Ryu, HY; Schlezinger, JJ; Sherr, DH | 1 |
| Dey, CS; Kumar, N | 1 |
| Becker, D; Brand, P; Knop, J; Valk, E; Zahn, S | 1 |
| Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G | 1 |
| Kobayashi, H; Minami, S; Saitoh, T; Shiraishi, S; Sugano, T; Wada, A; Yanagita, T; Yokoo, H | 1 |
| Chen, YE; Fu, M; Lin, Y; Mao, Z; Zhang, J; Zhu, X | 1 |
| Han, S; Huang, RP; Sidell, N; Wanichkul, T | 1 |
| Baker, SF; Brown, J; Davis, B; Hong, G; Khatoon, N | 1 |
| Alexander, GD; Isales, CM; Marrero, MB; Redd, H; Shaw, S; Wang, X | 1 |
| DeFronzo, RA; He, H; Mandarino, LJ; Miyazaki, Y | 1 |
| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| LAX, SR; RAVEL, JM; SHIVE, W; SMITH, LC | 1 |
| HENDERSON, JF; MAZEL, P | 1 |
| Arese, M; Audero, E; Bussolino, F; Cascone, I; Lanfrancone, L; Maniero, F; Napione, L | 1 |
| Antunes, E; De Nucci, G; Marcondes, S; Moreira, J; Thomazzi, SM | 1 |
| Leonardi, R; Roach, PL | 1 |
| Craig, AW; Di Ciano-Oliveira, C; Fan, L; Greer, PA; Kapus, A; Rotstein, OD; Weed, SA | 1 |
| Fink, AL; Han, S; Kaylor, J; Rajamani, S; Zhou, F; Zhu, M | 1 |
| Downs, DM; Martinez-Gomez, NC; Robers, M | 1 |
| Hazemann, I; Joachimiak, A; Karplus, M; Mitschler, A; Podjarny, A; Ruiz, F; Schneider, T | 1 |
| Behl, C; Conrad, S; Goodenough, S; Skutella, T | 1 |
| Abraham, SN; Duncan, MJ; Li, G; Wright, JR; Zaas, DW | 1 |
| Kaya, T; Sheu, SH; Vajda, S; Waxman, DJ | 1 |
| Amin, TJ; Gonias, SL; Jo, M; Marozkina, N; Parsons, SJ; Silva, CM; Thomas, KS | 1 |
| Behl, C; Goodenough, S; Pietrzik, C; Schleusner, D; Skutella, T | 1 |
| Ferrani-Kile, K; Leslie, SW | 1 |
| Bai, R; Dettin, LE; Glazer, RI; Kopelovich, L; Kopleovich, L; Kozikowski, AP; Russell, RG; Wei, ZL; Yin, Y | 1 |
| Abbot, EL; Buchan, KW; Hassall, DG; McCormack, JG; Reynet, C; Yeaman, SJ | 1 |
| Bezard, E; Guo, S; Zhao, B | 1 |
| Bodner, N; Edridge, S; Fink, AL; Hong, DP; Kaylor, J; Yamin, G | 1 |
| Champy, P; Duyckaerts, C; Féger, J; Hirsch, EC; Höglinger, GU; Khondiker, ME; Lannuzel, A; Lombes, A; Medja, F; Michel, PP; Oertel, WH; Prigent, A; Ruberg, M | 1 |
| Adachi, K; Hirata, T; Ishimaru, K; Ito, S; Kato, K; Kumai, H; Murata, O; Wakamatsu, K | 1 |
| Atlas, D; Bartov, O; Butterfield, DA; Sultana, R | 1 |
| Bemporad, F; Chiti, F; Stefani, M; Taddei, N | 1 |
| Kong, SK; Kwok, TT; Tsang, WP | 1 |
| Basak, S; Bhattacharyya, NP; Giri, K | 1 |
| Blot, B; Sadoul, R; Strappazzon, F; Torch, S; Trioulier, Y; Verna, JM | 1 |
| Boojar, MM; Shockravi, A | 1 |
| Fairhurst, SA; Kriek, M; Leonardi, R; Lowe, DJ; Martins, F; Roach, PL | 1 |
| Bartosz, G; Lewinska, A; Slota, E; Wnuk, M | 1 |
| Butterfield, DA; Sompol, P; St Clair, DK; St Clair, W; Tangpong, J; Vore, M | 1 |
| Araujo, JC; Gallick, GE; Gelovani, JG; Kim, SJ; Najjar, AM; Park, SI; Phillips, KA; Volgin, AY; Wang, Z; Zhang, J | 1 |
| Rao, KS | 1 |
| Biancalana, M; Koide, A; Koide, S; Makabe, K | 1 |
| Chan, P; Wang, L; Xu, S; Xu, X | 1 |
| Barnham, KJ; Cappai, R; Ciccotosto, GD; Curtain, CC; Drew, SC; Johanssen, T; Lal, V; Lau, TL; Masters, CL; Perez, K; Separovic, F; Smith, DG; Smith, JP; Tew, DJ; Wade, JD | 1 |
| Anantharam, V; Bravosanpedro, JM; Fuentes, JM; González-Polo, RA; Kanthasamy, AG; Morán, JM; Niso-Santano, M; Ortiz-Ortiz, MA; Soler, G | 1 |
| Bekard, IB; Dunstan, DE | 1 |
| Castiglia, S; Collino, M; Fantozzi, R; Kapoor, A; Thiemermann, C | 1 |
| Desai, KM; Dhar, A; Wu, L | 1 |
| Bornmann, WG; Daniels, L; Donato, NJ; Meng, F; Peng, Z; Peterson, LF; Quintás-Cardama, A; Roulston, D; Talpaz, M; Wu, J; Ying, Y | 1 |
| Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Galuppo, M; Kapoor, A; Mazzon, E; Paterniti, I; Thiemermann, C | 1 |
| Crisafulli, C; Cuzzocrea, S; Di Paola, R; Esposito, E; Galuppo, M; Genovese, T; Mazzon, E; Paterniti, I; Thiemermann, C | 1 |
| Dawood, BB; Makris, M; Mumford, A; Nash, CA; Senis, YA; Séverin, S; Watson, SP; Wilde, J | 1 |
| Aronowski, J; Grotta, JC; Savitz, SI; Sharma, S; Xi, X; Yang, B | 1 |
| Hirobe, T; Ito, S; Wakamatsu, K | 1 |
| DuBois, RN; Guo, L; Ning, W; Wang, D; Xie, D | 1 |
| Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W | 1 |
| Glazer, RI; Kopelovich, L; Upadhyay, G; Yin, Y; Yuan, H | 1 |
| Adamia, S; Barrett, R; Daley, JF; Fox, E; Frank, D; Griffin, JD; Nelson, E; Ray, A; Sattler, M; Weisberg, E; Zhang, C | 1 |
| Briguglio, F; Cordasco, G; Cuzzocrea, S; Di Paola, R; Mazzon, E; Militi, D; Oteri, G; Paterniti, I | 1 |
| Choi, EM | 1 |
| Cho, NL; Du, J; Ito, H; Lin, CI; Moore, FD; Ruan, DT; Whang, EE | 1 |
| Colvard, MD; Deliu, Z; Elseth, KM; Garcia, KD; Gouvas, E; Onul, A; Paradise, WA; Pestle, WJ; Radosevich, JA; Vesper, BJ | 1 |
| Fechner, G; Hooper, JN; Pham, NB; Quinn, RJ; Tran, TD | 1 |
| Büttner, R; Endl, E; Friedrichs, N; Hartmann, W; Heukamp, L; Huss, S; Kawai, A; Kindler, D; Kirfel, J; Larsson, O; Mechtersheimer, G; Michels, S; Penzel, R; Renner, M; Schirmacher, P; Sievers, E; Sonobe, H; Steiner, S; Tanaka, S; Trautmann, M; Wardelmann, E; Wurst, P | 1 |
| Banerjee, S; Clayton, GM; Garavito, RM; Ghebreselasie, K; Hermanson, DJ; Marnett, LJ; Xu, S | 1 |
| Bittman, R; Ohotski, J; Pyne, NJ; Pyne, S; Rosen, H | 1 |
| Carter, YM; Chen, H; Gamblin, TC; Kunnimalaiyaan, M; Kunnimalaiyaan, S | 1 |
| Adwan, TS; Anderson, SM; DeGregori, J; Reyland, ME; Wie, SM | 1 |
| Raleigh, DP; Serrano, AL; Tu, LH; Zanni, MT | 1 |
| Alavianmehr, MM; Ghahramani, M; Khoshaman, K; Yousefi, R | 1 |
| Chattopadhyay, K; Ghosh, R; Ghosh, S; Mukherjee, M | 1 |
| Akiba, H; Komiyama, M; Sumaoka, J; Tsumoto, K | 1 |
| Ferrari, GV; García, NA; Gutiérrez, EL; Massad, W; Miskoski, S; Muñoz, V; Natera, J; Paulina Montaña, M | 1 |
| Agarwal, AK; Garg, A; Sankella, S | 1 |
| Ito, S; Sarna, T; Wakamatsu, K | 1 |
| Dal-Pont, GC; Menegas, S; Peterle, BR; Quevedo, J; Resende, WR; Trajano, KS; Valvassori, SS; Varela, RB | 1 |
| Lei, X; Li, Y; Ruan, ZW; Shan, G; Yu, X; Zhang, B; Zheng, Y | 1 |
| Huttunen, J; Huttunen, KM; Markowicz-Piasecka, M; Montaser, A | 1 |
| Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; 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Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Astakhova, AA; Chistyakov, DV; Goriainov, SV; Sergeeva, MG | 1 |
| Abdallah, AEM; Helal, MHE; Mohamed, SS; Mohareb, RM | 1 |
4 review(s) available for thiazoles and tyrosine
| Article | Year |
|---|---|
[Antithyroid agents. 15].
Topics: Antithyroid Agents; Barbiturates; Carbimazole; Diiodotyrosine; Estrogens; Fluorides; Humans; Hyperthyroidism; Imidazoles; Iodine; Iodine Isotopes; Methylthiouracil; Perchlorates; Phenylacetates; Plant Extracts; Potassium; Propiophenones; Reserpine; Sodium; Sulfonamides; Thiazoles; Thiocyanates; Thiouracil; Tissue Extracts; Tyrosine; Vitamins | 1967 |
The biosynthesis of shikimate metabolites.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Animals; Anthranilate Synthase; Bacteria; Betalains; Catalysis; Chorismate Mutase; Coumarins; Flavonoids; Hydro-Lyases; Indoleacetic Acids; Indoles; Intramolecular Transferases; Lignans; Molecular Structure; Penicillium; Phenylalanine; Phenylpropionates; Phosphorus-Oxygen Lyases; Prephenate Dehydratase; Prephenate Dehydrogenase; Pristinamycin; Pyrrolnitrin; Quaternary Ammonium Compounds; Quinones; Shikimic Acid; Staurosporine; Tannins; Thiazoles; Thyroxine; Tryptophan; Tyrosine; Ubiquinone | 2001 |
Photodegradation of Eumelanin and Pheomelanin and Its Pathophysiological Implications.
Topics: Carboxylic Acids; Eye; Humans; Hydrogen Peroxide; Light; Melanins; Melanosomes; Pyrroles; Reactive Oxygen Species; Retinal Pigment Epithelium; Skin; Skin Aging; Thiazoles; Tyrosine; Ultraviolet Rays | 2018 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
3 trial(s) available for thiazoles and tyrosine
| Article | Year |
|---|---|
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.
Topics: Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Secretion; Male; Middle Aged; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Receptor, Insulin; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Tyrosine | 2003 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
131 other study(ies) available for thiazoles and tyrosine
| Article | Year |
|---|---|
The origin of the nitrogen atom in the thiazole ring of thiamine in Escherichia coli.
Topics: Escherichia coli; Mass Spectrometry; Nitrogen; Species Specificity; Substrate Specificity; Thiamine; Thiamine Pyrophosphatase; Thiazoles; Tyrosine | 1978 |
Thiamin biosynthesis in Saccharomyces cerevisiae. Origin of carbon-2 of the thiazole moiety.
Topics: Carbon Radioisotopes; Chemical Phenomena; Chemistry; Glycine; Methionine; Saccharomyces cerevisiae; Thiamine; Thiazoles; Tyrosine | 1979 |
The biosynthesis of the thiazole moiety of thiamine in Salmonella Typhimurium.
Topics: Alanine; Glycine; Methionine; Salmonella typhimurium; Thiamine; Thiazoles; Tyrosine | 1976 |
Inhibition of EGF-induced gastric mucosal calcium channel phosphorylation by ebrotidine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Ulcer Agents; Benzenesulfonates; Calcium Channels; Calcium Radioisotopes; Epidermal Growth Factor; Gastric Mucosa; Isradipine; Phosphorylation; Phosphotyrosine; Rats; Thiazoles; Tyrosine | 1992 |
2-Aryl-1,3-thiazolidines as masked sulfhydryl agents for inhibition of melanogenesis.
Topics: Alanine; Carboxylic Acids; Chromatography, Gel; Dihydroxyphenylalanine; Hydrolysis; Kinetics; Magnetic Resonance Spectroscopy; Melanins; Molecular Structure; Monophenol Monooxygenase; Spectrophotometry; Thiazines; Thiazoles; Tyrosine | 1991 |
Biosynthesis of thiamin. Different biosynthetic routes of the thiazole moiety of thiamin in aerobic organisms and anaerobic organisms.
Topics: Bacteria; Bacteria, Aerobic; Bacteria, Anaerobic; Glycine; Thiamine; Thiazoles; Tyrosine | 1987 |
Inhibitors of the pulmonary angiotensin I-converting enzyme.
Topics: Amino Acids; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cyclohexanecarboxylic Acids; Cyclopentanes; Female; In Vitro Techniques; Lung; Male; Methylamines; Peptides; Protease Inhibitors; Pyrrolidines; Pyrrolidonecarboxylic Acid; Rabbits; Snakes; Structure-Activity Relationship; Thiazoles; Thyrotropin; Tyrosine; Venoms | 1972 |
Stress-related effects of various inhibitors of catecholamine synthesis in the mouse.
Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Brain Chemistry; Catecholamines; Corticosterone; Depression, Chemical; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Fenclonine; Irritants; Male; Methylcellulose; Methyltyrosines; Mice; Motor Activity; Norepinephrine; Stress, Physiological; Thiazoles; Tyrosine; Tyrosine 3-Monooxygenase | 1971 |
[Tyrosine as a factor of biosynthesis of the thiazole moiety of thiamin in Escherichia coli].
Topics: Carbon Isotopes; Dose-Response Relationship, Drug; Escherichia coli; Mutation; Thiamine; Thiazoles; Tyrosine | 1972 |
Reversal by aromatic amino acids of 2-thiazole-DL-alanine inhibition of Salmonella typhimurium.
Topics: Amino Acids; Cell-Free System; Enzyme Repression; Feedback; Histidine; Hydro-Lyases; Membrane Transport Proteins; Phenylalanine; Salmonella typhimurium; Spectrophotometry; Stereoisomerism; Thiazoles; Tryptophan; Tyrosine | 1973 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Inhibition by phenylalanine of thiazole biosynthesis in Escherichia coli.
Topics: Depression, Chemical; Escherichia coli; Genetics, Microbial; Mutation; Phenylalanine; Shikimic Acid; Thiamine; Thiazoles; Tryptophan; Tyrosine | 1970 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
In vivo inhibition of dopamine beta-hydroxylase by 1-phenyl-3-(2-thiazolyl)-2-thiourea (U-14,624).
Topics: Adrenal Glands; Adrenalectomy; Animals; Brain; Brain Chemistry; Carbon Isotopes; Catecholamines; Disulfiram; Dopamine; Dopamine Antagonists; Hydrolases; Male; Metaraminol; Mice; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Rats; Species Specificity; Thiazoles; Thiourea; Time Factors; Tritium; Tyrosine | 1970 |
Isolation of 5-(beta-hydroxyethl)-4-methylthiazole-2-carboxylic acid, a metabolite related to thiamine biosynthesis in Escherichia coli.
Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Escherichia coli; Structure-Activity Relationship; Thiamine; Thiazoles; Tyrosine | 1980 |
Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chromans; Fibroblasts; Glucose; Humans; Hypoglycemic Agents; Immunoblotting; Immunosorbent Techniques; Insulin Resistance; Isoquinolines; Kinetics; Phosphorylation; Phosphotyrosine; Piperazines; Rats; Receptor, Insulin; Thiazoles; Thiazolidinediones; Troglitazone; Tyrosine | 1994 |
Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism.
Topics: 1-Phosphatidylinositol 4-Kinase; 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cyclic AMP; Enzyme Activation; Hypoglycemic Agents; Immunosorbent Techniques; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Kinetics; Male; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Thiazoles; Thiazolidinediones; Tyrosine | 1994 |
Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blotting, Western; Cell Line; Cytosol; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Macromolecular Substances; Phosphotyrosine; Pioglitazone; Protein Tyrosine Phosphatases; Raffinose; Rats; Receptor, Insulin; Recombinant Proteins; Swine; Thiazoles; Thiazolidinediones; Transfection; Tyrosine | 1995 |
Melanins in IGR 1 melanoma cells.
Topics: Chromatography, Liquid; Cysteinyldopa; Dicarboxylic Acids; Humans; Hydrolysis; Mass Spectrometry; Melanins; Melanoma; Monophenol Monooxygenase; Neoplasm Proteins; Oxidation-Reduction; Potassium Permanganate; Pyrroles; Sulfur; Thiazoles; Tumor Cells, Cultured; Tyrosine | 1994 |
Effect of ebrotidine on gastric mucosal EGF and PDGF receptor expression.
Topics: Animals; Benzenesulfonates; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Gastric Mucosa; Histamine H2 Antagonists; Phosphorylation; Platelet-Derived Growth Factor; Ranitidine; Rats; Receptors, Platelet-Derived Growth Factor; Thiazoles; Tyrosine | 1993 |
Increased level of phosphotyrosine in human dendritic cells under stimulation with contact sensitizers but not irritants.
Topics: Animals; Dendritic Cells; Dermatitis, Contact; Haptens; Humans; In Vitro Techniques; Irritants; Mice; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Thiazoles; Tyrosine | 1997 |
Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Cell Survival; Cells, Cultured; Chromium; Endothelium, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidants; Oxidation-Reduction; Oxygen Consumption; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tyrosine | 1997 |
Early phosphorylation events induced by DPIV/CD26-specific inhibitors.
Topics: Calcium; CD3 Complex; Cyclic AMP; Dipeptidyl Peptidase 4; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Mitogens; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tyrosine | 1998 |
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 2. Structure-activity relationship and optimization of the phenyl alkyl ether moiety.
Topics: Adipocytes; Animals; Cell Differentiation; Cell Line; DNA-Binding Proteins; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Lipids; Mice; Oxazoles; Propionates; Radioligand Assay; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Solubility; Structure-Activity Relationship; Thiazoles; Transcription Factors; Transfection; Tyrosine | 1998 |
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
Topics: Animals; Benzophenones; Chromans; Clone Cells; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Immunohistochemistry; Logistic Models; Obesity; Phenotype; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine | 1999 |
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Dogs; Echocardiography; Female; Interleukin-1; Male; Myocardium; Nitrates; Random Allocation; Stroke Volume; Superoxides; Thiazoles; Tyrosine; Ventricular Dysfunction, Left | 1999 |
Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antifungal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radicals; Glutathione Transferase; Heart Ventricles; Hydrogen Peroxide; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Methacrylates; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Osmotic Pressure; Oxidative Stress; Phenylephrine; Phosphorylation; Protein Kinases; Rats; Signal Transduction; Thiazoles; Time Factors; Tyrosine; Uncoupling Agents | 2000 |
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells.
Topics: Antineoplastic Agents; Biological Transport; Cell Division; Cell Movement; Cell Survival; Cells, Cultured; Chemokine CCL2; Chromans; Cytotoxins; Gene Expression; Hepatitis; Humans; Interleukin-1; Ligands; Liver; Liver Cirrhosis; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Prostaglandin D2; Proto-Oncogenes; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factor AP-1; Transcription Factors; Troglitazone; Tyrosine; Wound Healing | 2000 |
Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice.
Topics: Animals; Arteriosclerosis; Base Sequence; CD36 Antigens; DNA Primers; Female; Gene Expression; Humans; Insulin Resistance; Ligands; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazoles; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Rosiglitazone; Scavenger Receptors, Class B; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Rac is involved in early TCR signaling.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; CD3 Complex; Cytoskeleton; Gene Expression Regulation; Genetic Vectors; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Mutation; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; rac GTP-Binding Proteins; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Thiazoles; Thiazolidines; Transfection; Tyrosine | 2000 |
Formation of nitric oxide from nitroxyl anion: role of quinones and ferricytochrome c.
Topics: Animals; Aorta, Thoracic; Cytochrome c Group; Electron Transport Complex III; In Vitro Techniques; Male; Methacrylates; Monophenol Monooxygenase; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Nitrogen Oxides; Oxidation-Reduction; Quinones; Rats; Rats, Wistar; Thiazoles; Tyrosine; Ubiquinone; Vasodilation; Vasodilator Agents | 2001 |
Non-thiazolidinedione insulin sensitiser shows promise.
Topics: Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Drug Industry; Humans; Hypoglycemic Agents; Multicenter Studies as Topic; Oxazoles; Thiazoles; Tyrosine | 2000 |
Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Deoxyglucose; Diet, Sodium-Restricted; Enzyme Activation; Glucose Clamp Technique; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Thiazoles; Thiazolidinediones; Tyrosine | 2001 |
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2001 |
The actin cytoskeleton is required for the trafficking of the B cell antigen receptor to the late endosomes.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Cross-Linking Reagents; Cytochalasin D; Cytoskeleton; Depsipeptides; Dose-Response Relationship, Drug; Endosomes; Humans; Hybridomas; Lymphocyte Activation; Lysosomes; Mice; Microscopy, Electron; Microscopy, Fluorescence; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; Phosphorylation; Protein Transport; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Tyrosine | 2001 |
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.
Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine | 2001 |
A src family tyrosine kinase inhibits neurotransmitter release from neuronal cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Size; Cells, Cultured; Cerebellum; Cytoskeletal Proteins; Dopamine; Focal Adhesion Kinase 2; Gene Expression; Glutamic Acid; Humans; Neurons; Oncogene Protein pp60(v-src); Paxillin; PC12 Cells; Phalloidine; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; src-Family Kinases; Thiazoles; Thiazolidines; Tyrosine | 2001 |
Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats.
Topics: Animals; CD36 Antigens; Chromans; Emulsions; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucose; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Lecithins; Ligands; Liver; Male; Membrane Glycoproteins; Muscle, Skeletal; Organic Anion Transporters; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Safflower Oil; Soybean Oil; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine | 2001 |
Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation.
Topics: 3T3 Cells; Adenoviridae; Adipocytes; Animals; Benzophenones; Cell Membrane; Drug Synergism; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Green Fluorescent Proteins; Hypoglycemic Agents; Insulin; Luminescent Proteins; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Mutation; Oxazoles; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tyrosine | 2001 |
Inhibition of the Escherichia coli pyruvate dehydrogenase complex E1 subunit and its tyrosine 177 variants by thiamin 2-thiazolone and thiamin 2-thiothiazolone diphosphates. Evidence for reversible tight-binding inhibition.
Topics: Amino Acid Sequence; Base Sequence; Circular Dichroism; DNA Primers; Enzyme Inhibitors; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyruvate Dehydrogenase Complex; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Thiamine; Thiazoles; Tyrosine | 2001 |
Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells.
Topics: Acetophenones; Adenoviridae; Animals; Aorta, Thoracic; Apoptosis; Benzopyrans; Blotting, Western; Carbazoles; Cell Division; Cells, Cultured; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hydroquinones; Indoles; Insulin; Isoenzymes; Kinetics; Ligands; Mice; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine; Up-Regulation; Vanadates | 2001 |
A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity.
Topics: Adipocytes; Amino Acids; Animals; Binding Sites; Blood Glucose; Body Weight; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Fluorenes; Gene Expression Regulation; Genes, Reporter; Hypoglycemic Agents; Insulin Resistance; Leucine; Ligands; Male; Mice; Mice, Inbred Strains; Molecular Structure; Protein Binding; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Spectrometry, Mass, Electrospray Ionization; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Tyrosine | 2001 |
IL-10 promotes survival of microglia without activating Akt.
Topics: Animals; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; DNA-Binding Proteins; Enzyme Activation; Insulin-Like Growth Factor I; Interleukin-10; Mice; Microglia; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Interleukin; Receptors, Interleukin-10; Serine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Trans-Activators; Tyrosine | 2002 |
Troglitazone inhibits growth and improves insulin signaling by suppression of angiotensin II action in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cell Division; Cells, Cultured; Chromans; Depression, Chemical; DNA; Growth Substances; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Thiazoles; Thiazolidinediones; Troglitazone; Tyrosine | 2002 |
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.
Topics: Animals; Benzophenones; Cell Line; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Peroxisomes; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin D2; Protein Kinase C; Proto-Oncogene Proteins c-raf; ras Proteins; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Superoxides; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis.
Topics: Animals; Cerebellum; Cerebral Cortex; DNA-Binding Proteins; Encephalomyelitis, Autoimmune, Experimental; Female; Glycoproteins; Humans; Hypoglycemic Agents; I-kappa B Proteins; Ligands; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazoles; Peptide Fragments; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Remission Induction; Spinal Cord; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
Topics: Animals; Blood Glucose; Carrier Proteins; Energy Metabolism; Fatty Acids; Fatty Acids, Nonesterified; Homeostasis; Humans; Ion Channels; Isoenzymes; Ketones; Lactic Acid; Liver Glycogen; Mice; Mice, Knockout; Mitochondrial Proteins; Muscle, Skeletal; Oxazoles; Oxidation-Reduction; Physical Conditioning, Animal; Protein Kinases; Rats; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors; Transcription, Genetic; Tyrosine; Uncoupling Protein 3 | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
A Crk-II/TC10 signaling pathway is required for osmotic shock-stimulated glucose transport.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Deoxyglucose; Depsipeptides; Electrophoresis, Polyacrylamide Gel; Glucose; Glucose Transporter Type 4; Isoenzymes; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Osmosis; Osmotic Pressure; Peptides, Cyclic; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Precipitin Tests; Protein Binding; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; rho GTP-Binding Proteins; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Type C Phospholipases; Tyrosine | 2002 |
Glycoprotein Ib cross-linking/ligation on echicetin-coated surfaces or echicetin-IgMkappa in stirred suspension activates platelets by cytoskeleton modulated calcium release.
Topics: Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Carrier Proteins; Cell Adhesion; Cytochalasin D; Cytoskeleton; Humans; Immunoglobulin M; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Nitric Oxide; Oxazoles; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Proteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidines; Tyrosine; Viper Venoms; von Willebrand Factor | 2002 |
TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney.
Topics: Animals; Coloring Agents; Dose-Response Relationship, Drug; Hydrogen Peroxide; Immunohistochemistry; Kidney; Kidney Diseases; Male; Mice; Nitrogen; Oxidative Stress; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Tetrazolium Salts; Thiazoles; Triacetoneamine-N-Oxyl; Tyrosine; Urine | 2002 |
Peroxisome proliferator-activated receptor gamma-mediated NF-kappa B activation and apoptosis in pre-B cells.
Topics: Animals; Apoptosis; B-Lymphocytes; Bone Marrow Cells; Cell Line; Cell Line, Transformed; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxazoles; Peroxisome Proliferators; Peroxisomes; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2002 |
Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells.
Topics: Animals; Biological Transport; Cell Differentiation; Cells, Cultured; Culture Media, Serum-Free; Deoxyglucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Myoblasts; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pioglitazone; Receptor, Insulin; Rosiglitazone; Thiazoles; Thiazolidinediones; Tyrosine | 2003 |
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
Topics: Acetates; Anti-Infective Agents; Antioxidants; Cysteine; Dendritic Cells; Ethylmaleimide; Humans; Interleukin-1; Lysine; Maleimides; MAP Kinase Signaling System; Monocytes; Phosphorylation; Picryl Chloride; Succinimides; Sulfhydryl Compounds; Sulfhydryl Reagents; Thiazoles; Tyrosine | 2003 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
Distinct effects of ketone bodies on down-regulation of cell surface insulin receptor and insulin receptor substrate-1 phosphorylation in adrenal chromaffin cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adrenal Glands; Animals; Cattle; Chromaffin Cells; Chromans; Clofibrate; Culture Media; Down-Regulation; Epoprostenol; Insulin; Insulin Receptor Substrate Proteins; Iodine Radioisotopes; Ketone Bodies; Membrane Proteins; Phosphoproteins; Phosphorylation; Receptor, Insulin; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Tyrosine | 2003 |
Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.
Topics: Anilides; Aorta; Chromans; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Humans; Hypoglycemic Agents; Inhibitor of Differentiation Protein 2; Muscle, Smooth, Vascular; Oxazoles; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; RNA, Messenger; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine | 2003 |
Cytokine regulation by peroxisome proliferator-activated receptor gamma in human endometrial cells.
Topics: Benzophenones; Colony-Stimulating Factors; Cytokines; Endometrium; Epithelial Cells; Female; Humans; Interleukin-6; Ligands; Phenylacetates; Prostaglandin D2; Protein Array Analysis; Protein Isoforms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2003 |
PPAR gamma-dependent anti-inflammatory action of rosiglitazone in human monocytes: suppression of TNF alpha secretion is not mediated by PTEN regulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromones; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Monocytes; Morpholines; Oxazoles; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins; Tyrosine | 2003 |
High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway.
Topics: Acetophenones; Aldehyde Reductase; Angiotensin II; Animals; Antibodies; Aorta; Benzothiazoles; Cells, Cultured; Drug Synergism; Electroporation; Enzyme Inhibitors; Glucose; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Muscle, Smooth, Vascular; NADPH Oxidases; Oligonucleotides, Antisense; Phosphoproteins; Phosphorylation; Phthalazines; Polymers; Protein Kinase C; Protein Kinase C beta; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Thiazoles; Tyrosine; Vasoconstrictor Agents | 2003 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
THE EFFECTS OF PHENYLALANINE AND TYROSINE ANALOGS ON THE SYNTHESIS AND ACTIVITY OF 3-DEOXY-D-ARABINO-HEPTULOSONIC ACID 7-PHOSPHATE SYNTHETASES.
Topics: Carbohydrate Metabolism; Enzyme Inhibitors; Escherichia coli; Ligases; Mutation; Naphthalenes; Pharmacology; Phenylalanine; Phosphates; Pyridines; Research; Thiazoles; Thiophenes; Tyrosine | 1964 |
ON THE RELATIONSHIP BETWEEN LIPID SOLUBILITY AND MICROSOMAL METABOLISM OF DRUGS.
Topics: Animals; Barbiturates; Lipids; Liver; Metabolism; Mice; Microsomes; Nucleosides; Purines; Puromycin; Pyrimidines; Rats; Research; Solubility; Theobromine; Theophylline; Thiazoles; Tyrosine | 1965 |
Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Angiopoietin-1; Animals; Binding Sites; Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Coloring Agents; COS Cells; Endothelial Cells; Endothelium, Vascular; Genes, Dominant; Glutathione Transferase; Humans; Immunoblotting; Ligands; MAP Kinase Signaling System; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; Receptor, TIE-2; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro.
Topics: Adolescent; Adult; Blotting, Western; Cell Survival; Chemotaxis, Leukocyte; Cyclic GMP; Eosinophils; Female; Humans; In Vitro Techniques; Male; Middle Aged; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide Donors; Nitroprusside; Penicillamine; Tetrazolium Salts; Thiazoles; Tyrosine | 2004 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity.
Topics: Adenosine; Bacterial Proteins; Carbon-Sulfur Lyases; Carrier Proteins; Cell-Free System; Chromatography, High Pressure Liquid; Culture Media; Cysteine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Ligases; Models, Chemical; NADP; Nucleotidyltransferases; Plasmids; S-Adenosylmethionine; Sulfurtransferases; Thiamine; Thiazoles; Time Factors; Tyrosine | 2004 |
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cortactin; Cricetinae; Enzyme Activation; Microfilament Proteins; Osmotic Pressure; Peptides; Phosphorylation; Phosphotyrosine; Polymers; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Thiazoles; Thiazolidines; Transfection; Tyrosine | 2004 |
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.
Topics: alpha-Synuclein; Anaerobiosis; Benzothiazoles; Circular Dichroism; Escherichia coli; Flavanones; Flavonoids; Humans; Light; Lysine; Microscopy, Atomic Force; Molecular Weight; Nerve Tissue Proteins; Oxidation-Reduction; Protein Conformation; Quinones; Scattering, Radiation; Solubility; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Synucleins; Thiazoles; Tyrosine | 2004 |
Mutational analysis of ThiH, a member of the radical S-adenosylmethionine (AdoMet) protein superfamily.
Topics: Alleles; Amino Acid Motifs; Amino Acid Sequence; DNA Mutational Analysis; Escherichia coli Proteins; Iron-Sulfur Proteins; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oxygen; Phenotype; Plasmids; Polymerase Chain Reaction; S-Adenosylmethionine; Salmonella enterica; Thiamine Pyrophosphatase; Thiazoles; Time Factors; Tyrosine | 2004 |
The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48.
Topics: Aldehyde Reductase; Binding Sites; Carboxylic Acids; Crystallography, X-Ray; Enzyme Inhibitors; Fluorobenzenes; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; NADP; Protein Structure, Tertiary; Protons; Thiazoles; Tyrosine | 2004 |
Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
Topics: Animals; Behavior, Animal; Blotting, Western; Butadienes; Cell Death; Cell Survival; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Lithium Chloride; Male; Mice; Mitogen-Activated Protein Kinase 1; Neurotoxicity Syndromes; Nitriles; Organ Culture Techniques; Phosphorylation; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Pseudomonas invasion of type I pneumocytes is dependent on the expression and phosphorylation of caveolin-2.
Topics: Animals; Caveolin 1; Caveolin 2; Caveolins; Cell Adhesion; Cell Line; Cells, Cultured; Coloring Agents; Cystic Fibrosis; Epithelial Cells; Immunoprecipitation; Lipid Metabolism; Lipids; Lung; Membrane Microdomains; Mice; Microscopy, Confocal; Microscopy, Electron; Phosphorylation; Pseudomonas; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA Interference; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
Topics: Alkanesulfonates; Binding Sites; Cinnamates; Computational Biology; Humans; Ligands; Oxazines; Oxazoles; Phenylpropionates; PPAR gamma; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Rosiglitazone; Solvents; Thiazoles; Thiazolidinediones; Thiazolidines; Tyrosine | 2005 |
Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; CHO Cells; Coloring Agents; Cricetinae; DNA; DNA-Binding Proteins; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; Humans; Immunoprecipitation; Kinetics; Milk Proteins; Mutation; Pertussis Toxin; Phosphorylation; Prognosis; Protein Binding; RNA, Small Interfering; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator | 2005 |
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Phosphorylation; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Modulation of protein tyrosine phosphatase activity alters the subunit assembly in native N-methyl-D-aspartate receptor complex.
Topics: Animals; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoprecipitation; In Vitro Techniques; Mass Spectrometry; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Tetrazolium Salts; Thiazoles; Tyrosine; Vanadates | 2005 |
Peroxisome proliferator-activated receptor delta and gamma agonists differentially alter tumor differentiation and progression during mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Adenosquamous; Carcinoma, Ductal; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; Female; Gene Expression Profiling; Mammary Neoplasms, Experimental; Mice; Oxazoles; PPAR delta; PPAR gamma; Thiazoles; Tyrosine | 2005 |
Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells.
Topics: Butyrates; Cells, Cultured; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Humans; Insulin; Isoenzymes; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts, Skeletal; Oxazoles; Phenylurea Compounds; PPAR alpha; PPAR delta; PPAR gamma; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA, Messenger; Thiazoles; Tyrosine | 2005 |
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway.
Topics: Annexin A5; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; Free Radicals; Guanosine Triphosphate; Humans; Membrane Potentials; Mitochondria; Models, Biological; Neurons; Nitric Oxide; Oxidopamine; Oxygen; Parkinson Disease; Phenols; Polyphenols; Quinones; Reactive Oxygen Species; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2005 |
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Tryptophan; Tyrosine | 2005 |
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.
Topics: alpha-Synuclein; Amyloid beta-Peptides; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Behavior, Animal; Benzothiazoles; Body Weight; Caspase 3; Caspases; Cell Death; Cerebral Cortex; Cytarabine; Diagnostic Imaging; Dopamine and cAMP-Regulated Phosphoprotein 32; Doxorubicin; Dystonia; Electron Transport Complex III; Enzyme Activation; Glial Fibrillary Acidic Protein; Immunohistochemistry; Locomotion; Male; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Posture; Psychomotor Performance; Rats; Rats, Inbred Lew; Rotenone; tau Proteins; Tauopathies; Thiazoles; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase; Ubiquitin; Uncoupling Agents | 2005 |
The histological analysis, colorimetric evaluation, and chemical quantification of melanin content in 'suntanned' fish.
Topics: Animals; Colorimetry; Melanins; Melanocytes; Sea Bream; Skin; Skin Pigmentation; Sunlight; Thiazoles; Tyrosine; Ultraviolet Rays | 2005 |
Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity.
Topics: Acetylcysteine; Amides; Amyloid beta-Peptides; Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Neurons; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Amino Acid Substitution; Amyloid; Benzothiazoles; Birefringence; Circular Dichroism; Congo Red; Data Interpretation, Statistical; Humans; Hydrophobic and Hydrophilic Interactions; Muscles; Phase Transition; Phenylalanine; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Thiazoles; Trifluoroethanol; Tyrosine | 2006 |
Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; Down-Regulation; Drug Resistance, Neoplasm; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides; Phosphorylation; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
pH-dependent self-assembly of polyalanine peptides.
Topics: Benzothiazoles; Biophysics; Cell Nucleus; Humans; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Muscles; Muscular Dystrophy, Oculopharyngeal; Peptides; Poly(A)-Binding Protein II; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Temperature; Thiazoles; Tyrosine | 2007 |
Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Survival; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Mice; Mutagenesis; Neurons; Potassium; Potassium Chloride; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine | 2007 |
On the cytotoxicity and status of oxidative stress of two novel synthesized tri-aza macrocyclic diamides as studied in the V79 cell lines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Catalase; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Deoxyguanosine; Diamide; DNA Damage; Glutathione Peroxidase; Lipid Peroxidation; Macrocyclic Compounds; Malondialdehyde; Oxidative Stress; Proteins; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tyrosine; Vitamin E | 2007 |
Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.
Topics: Escherichia coli; Escherichia coli Proteins; Molecular Structure; Nucleotidyltransferases; Protein Structure, Quaternary; Protein Subunits; Thiamine; Thiazoles; Tyrosine | 2007 |
Total anti-oxidant capacity of cell culture media.
Topics: Antioxidants; Benzothiazoles; Chlorides; Colorimetry; Culture Media; Cysteine; Ferric Compounds; Oxidation-Reduction; Phenolsulfonphthalein; Spectrophotometry; Sulfonic Acids; Thiazoles; Tryptophan; Tyrosine | 2007 |
Tumor necrosis factor alpha-mediated nitric oxide production enhances manganese superoxide dismutase nitration and mitochondrial dysfunction in primary neurons: an insight into the role of glial cells.
Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Coculture Techniques; Immunohistochemistry; Mice; Mice, Knockout; Mitochondria; Neuroglia; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha; Tyrosine | 2008 |
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model.
Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Crk-Associated Substrate Protein; Dasatinib; Disease Models, Animal; Drug Delivery Systems; Focal Adhesion Kinase 1; Humans; Lymphatic Metastasis; Male; Mice; Mice, Nude; Prostatic Neoplasms; Pyrimidines; src-Family Kinases; Thiazoles; Tumor Burden; Tumor Cells, Cultured; Tyrosine; Xenograft Model Antitumor Assays | 2008 |
Molecular understanding of copper and iron interaction with alpha-synuclein by fluorescence analysis.
Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Binding Sites; Copper; Fluorescence; Fluorescent Dyes; Humans; Iron; Protein Binding; Thiazoles; Tyrosine | 2008 |
Molecular mechanism of thioflavin-T binding to the surface of beta-rich peptide self-assemblies.
Topics: Benzothiazoles; Binding Sites; Crystallography, X-Ray; Models, Biological; Models, Molecular; Peptides; Protein Structure, Secondary; Surface Properties; Thiazoles; Tyrosine | 2009 |
(-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation.
Topics: Adrenergic Agents; Analysis of Variance; Catechin; Cell Death; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Neuroblastoma; Neuroprotective Agents; Oxidopamine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium; Tyrosine | 2009 |
Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Topics: Amyloid beta-Peptides; Animals; Annexin A5; Benzothiazoles; Biophysics; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Electron Spin Resonance Spectroscopy; Embryo, Mammalian; Hydrogen Peroxide; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Neurons; Patch-Clamp Techniques; Protein Binding; Protein Conformation; Protein Structure, Secondary; Thiazoles; Time Factors; Tyrosine | 2011 |
Curcumin enhances paraquat-induced apoptosis of N27 mesencephalic cells via the generation of reactive oxygen species.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Line, Transformed; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation; Herbicides; Hydrogen Peroxide; Mesencephalon; Neurons; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Paraquat; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tyrosine; Vitamin E | 2009 |
Tyrosine autofluorescence as a measure of bovine insulin fibrillation.
Topics: Anilino Naphthalenesulfonates; Animals; Benzothiazoles; Biophysics; Cattle; Insulin; Kinetics; Light; Protein Conformation; Protein Structure, Secondary; Scattering, Radiation; Spectrometry, Fluorescence; Temperature; Thiazoles; Tyrosine | 2009 |
Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat.
Topics: Animals; Cyclooxygenase 2; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Oxazoles; Phosphorylation; PPAR alpha; PPAR delta; PPAR-beta; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazoles; Tyrosine | 2010 |
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Male; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrosine | 2010 |
ON012380, a putative BCR-ABL kinase inhibitor with a unique mechanism of action in imatinib-resistant cells.
Topics: Animals; Antineoplastic Agents; Benzamides; Benzene Derivatives; Cells, Cultured; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Interleukin-3; K562 Cells; Mice; Mutation; Phosphorylation; Piperazines; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Tyrosine | 2010 |
Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury.
Topics: Animals; Apoptosis; Cytokines; Enzyme Induction; Fas Ligand Protein; Male; Mice; Neutrophil Infiltration; Nitric Oxide Synthase; Peroxidase; PPAR delta; PPAR-beta; Spinal Cord Injuries; Sulfones; Thiazoles; Thiophenes; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Apoptosis; bcl-2-Associated X Protein; Carrageenan; I-kappa B Proteins; Lipid Peroxidation; Lung; Male; Mice; Neutrophils; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Pleurisy; PPAR delta; PPAR-beta; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Tyrosine | 2010 |
Src family kinases are essential for primary aggregation by G(i) -coupled receptors.
Topics: Aza Compounds; Blood Platelets; Cyclic AMP; Dasatinib; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Activation; Platelet-Rich Plasma; Protein Kinase Inhibitors; Pyrimidines; Receptors, Purinergic P2Y12; src-Family Kinases; Thiazoles; Tyrosine | 2010 |
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways.
Topics: Analysis of Variance; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glutamic Acid; Hypoxia; Interleukin-10; Neurons; Neurotoxins; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-18; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tyrosine | 2011 |
The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but not pheomelanin synthesis.
Topics: Alleles; Animals; Carrier Proteins; Crosses, Genetic; Female; Hair; Male; Melanins; Membrane Proteins; Mice; Mice, Congenic; Thiazoles; Tyrosine | 2011 |
Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Inhibitor of Apoptosis Proteins; Oxazoles; PPAR delta; PPAR gamma; Survivin; Thiazoles; Tyrosine | 2012 |
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays | 2011 |
Stem cell antigen-1 deficiency enhances the chemopreventive effect of peroxisome proliferator-activated receptorγ activation.
Topics: Animals; Anticarcinogenic Agents; Antigens, Ly; Antineoplastic Agents; Cell Line, Tumor; Genetic Predisposition to Disease; Heterozygote; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oxazoles; Phenotype; PPAR gamma; RNA Interference; Signal Transduction; Thiazoles; Tyrosine | 2012 |
Reversible resistance induced by FLT3 inhibition: a novel resistance mechanism in mutant FLT3-expressing cells.
Topics: Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Stability; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Leukemia, Myeloid, Acute; Mutation; Phosphorylation; Piperazines; Protein Kinase Inhibitors; RNA, Messenger; Signal Transduction; Staurosporine; Thiazoles; Tyrosine; Up-Regulation | 2011 |
Emerging role of PPAR-β/δ in inflammatory process associated to experimental periodontitis.
Topics: Animals; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Bone Resorption; Capillary Permeability; Cytokines; Dose-Response Relationship, Drug; Male; Neutrophil Infiltration; NF-kappa B; Nitric Oxide Synthase Type II; Periodontitis; PPAR delta; PPAR-beta; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrosine | 2011 |
Deoxyactein Isolated from Cimicifuga racemosa protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antifungal Agents; Antimycin A; Calcium; Cardiolipins; Cimicifuga; Coloring Agents; Cyclic AMP Response Element-Binding Protein; Electron Transport Complex IV; Membrane Potential, Mitochondrial; Mice; Mitochondria; Oncogene Protein v-akt; Osteoblasts; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Saponins; Tetrazolium Salts; Thiazoles; Thioredoxin-Disulfide Reductase; Triterpenes; Tyrosine | 2013 |
Global tyrosine kinome profiling of human thyroid tumors identifies Src as a promising target for invasive cancers.
Topics: Adenocarcinoma, Papillary; Cell Proliferation; Dasatinib; High-Throughput Screening Assays; Humans; Metabolome; Molecular Targeted Therapy; Mutation; Neoplasm Invasiveness; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured; Tyrosine; Up-Regulation | 2012 |
Application of immunohistochemical staining to detect antigen destruction as a measure of tissue damage.
Topics: Animals; Antibodies; Antibody Specificity; Antigens; Coloring Agents; Cross Reactions; Eosine Yellowish-(YS); Fixatives; Formaldehyde; Hematoxylin; Hot Temperature; Immunohistochemistry; Paraffin Embedding; Protein Denaturation; Protein Folding; Receptor, ErbB-2; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles; Tyrosine | 2012 |
Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa.
Topics: Alkaloids; Animals; Australia; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Hydrocarbons, Brominated; Male; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxazoles; Porifera; Thiazoles; Tyrosine | 2013 |
SRC signaling is crucial in the growth of synovial sarcoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Dasatinib; Drug Synergism; Enzyme Activation; Humans; Mice; Mitosis; Neoplasm Proteins; Phosphorylation; Phosphotransferases; Protein Array Analysis; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Repressor Proteins; rhoA GTP-Binding Protein; RNA Interference; Sarcoma, Synovial; Signal Transduction; src-Family Kinases; Thiazoles; Translocation, Genetic; Tumor Burden; Tyrosine; Xenograft Model Antitumor Assays | 2013 |
Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Binding Sites; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Hydrogen Bonding; Leucine; Meloxicam; Mice; Mutation; Piroxicam; Protein Structure, Secondary; Serine; Thiazines; Thiazoles; Tyrosine; Water | 2014 |
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CSK Tyrosine-Protein Kinase; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Estrogen; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Thiazoles; Tyrosine | 2014 |
Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth.
Topics: Antineoplastic Agents; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Biomarkers, Tumor; Bone Marrow Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromogranin A; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neuroblastoma; Phosphorylation; Thiazoles; Tyrosine; Urea | 2014 |
Inhibiting tyrosine phosphorylation of protein kinase Cδ (PKCδ) protects the salivary gland from radiation damage.
Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Animals; Apoptosis; Cell Nucleus; CSK Tyrosine-Protein Kinase; Dasatinib; DNA Damage; Female; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Phosphorylation; Protein Binding; Protein Kinase C-delta; Proto-Oncogene Proteins c-abl; Pyrimidines; Salivary Glands; src-Family Kinases; Thiazoles; Tyrosine | 2014 |
Mutational analysis of preamyloid intermediates: the role of his-tyr interactions in islet amyloid formation.
Topics: Amino Acid Sequence; Amyloid; Benzothiazoles; DNA Mutational Analysis; Genetic Variation; Histidine; Humans; Hydrogen-Ion Concentration; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Spectrum Analysis; Thiazoles; Tyrosine | 2014 |
The impact of calcium ion on structure and aggregation propensity of peroxynitrite-modified lens crystallins: new insights into the pathogenesis of cataract disorders.
Topics: Animals; Benzothiazoles; Calcium; Cattle; Crystallins; Hydrophobic and Hydrophilic Interactions; Lens, Crystalline; Oxidants; Peroxynitrous Acid; Protein Aggregates; Protein Carbonylation; Protein Stability; Proteolysis; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Tyrosine | 2015 |
pH-induced structural change of a multi-tryptophan protein MPT63 with immunoglobulin-like fold: identification of perturbed tryptophan residue/residues.
Topics: Acrylamide; Amino Acid Motifs; Anilino Naphthalenesulfonates; Bacterial Proteins; Benzothiazoles; Cloning, Molecular; Escherichia coli; Fluorescent Dyes; Gene Expression; Hydrogen Bonding; Hydrogen-Ion Concentration; Immunoglobulins; Molecular Sequence Data; Mycobacterium tuberculosis; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Static Electricity; Thermodynamics; Thiazoles; Tryptophan; Tyrosine | 2015 |
Click conjugation of a binuclear terbium(III) complex for real-time detection of tyrosine phosphorylation.
Topics: Click Chemistry; Dasatinib; Luminescence; Molecular Structure; Organometallic Compounds; Peptides; Phosphorylation; Phosphotransferases; Protein Kinase Inhibitors; Pyrimidines; Terbium; Thiazoles; Time Factors; Tyrosine | 2015 |
Scavenging of photogenerated ROS by Oxicams. Possible biological and environmental implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Free Radical Scavengers; Light; Meloxicam; Oxidation-Reduction; Photolysis; Piroxicam; Pyridines; Reactive Oxygen Species; Rhodamines; Riboflavin; Singlet Oxygen; Superoxides; Thiazines; Thiazoles; Tryptophan; Tyrosine; Water Pollutants, Chemical | 2015 |
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine | 2016 |
Inhibition of GSK-3β on Behavioral Changes and Oxidative Stress in an Animal Model of Mania.
Topics: Aldehydes; Animals; Antioxidants; Behavior, Animal; Bipolar Disorder; Catalase; Dinoprost; Disease Models, Animal; Glutathione Peroxidase; Glycogen Synthase Kinase 3 beta; Lipid Peroxidation; Male; Motor Activity; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Submitochondrial Particles; Superoxide Dismutase; Superoxides; Thiazoles; Tyrosine; Urea | 2019 |
Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A.
Topics: Alkenes; Aquatic Organisms; Cyanobacteria; Depsipeptides; Disulfides; Enzyme Activation; Histone Deacetylase Inhibitors; Histone Deacetylases; Thiazoles; Tyrosine | 2019 |
Hemocompatible LAT1-inhibitor can induce apoptosis in cancer cells without affecting brain amino acid homeostasis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoxazoles; Brain; Brain Chemistry; Carboxylic Acids; Drug Synergism; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Injections, Intraperitoneal; Large Neutral Amino Acid-Transporter 1; Leucine; Male; MCF-7 Cells; Mice; Myocytes, Smooth Muscle; NF-kappa B; Norbornanes; Primary Cell Culture; Pyridines; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Tyrosine | 2020 |
Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes.
Topics: Anilides; Animals; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fenofibrate; Interleukin-10; Lipopolysaccharides; MAP Kinase Kinase 4; Oxazoles; Oxylipins; p38 Mitogen-Activated Protein Kinases; PPAR gamma; PPAR-beta; Rats; Rats, Wistar; Rosiglitazone; Thiazoles; Tumor Necrosis Factor-alpha; Tyrosine | 2020 |
New Approaches for the Synthesis of 2,3,5,6-Tetrahydrobenzo[d]thiazole Derivatives and their Anti-Proliferative, c-Met Enzymatic Activity and Tyrosine Kinases Inhibitions.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Protein Kinase Inhibitors; Quinolines; Structure-Activity Relationship; Thiazoles; Tyrosine | 2022 |