thiazoles has been researched along with tryptophan in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (14.44) | 18.7374 |
| 1990's | 4 (4.44) | 18.2507 |
| 2000's | 34 (37.78) | 29.6817 |
| 2010's | 37 (41.11) | 24.3611 |
| 2020's | 2 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Appella, E; Inman, JK; Jörnvall, H | 1 |
| Matsushima, M | 1 |
| Bryan, GT; Hayashida, S; Pamukcu, AM; Wang, CY | 1 |
| Bahramian, MB; Middleton, RB | 1 |
| Mandula, BB; Mosteller, RD | 1 |
| Johnson, GA; Kim, EG | 1 |
| Blumenthal, A; Ezekiel, DH | 1 |
| Iwashima, A; Nose, Y | 1 |
| Biaglow, JE; Mieyal, JJ; Sable, HZ; Suchy, J | 1 |
| Bogulska, M; Katzenellenbogen, E; Lugowski, C; Romanowska, E | 1 |
| Nose, T; Sotomura, M; Tanaka, A; Tanaka, H; Tsunetoshi, Y | 1 |
| Cohen, SM; Murasaki, G | 1 |
| Cohen, SM; Friedell, GH; Fukushima, S; Jacobs, JB | 1 |
| Last, RL; Zhao, J | 1 |
| Last, RL; Williams, CC; Zhao, J | 1 |
| Cao, Y; Goodin, DB; McRee, DE; Musah, RA; Wilcox, SK | 1 |
| Zook, M | 1 |
| Akhtar, NJ; Liang, JJ; Sun, TX | 1 |
| Hatters, DM; Howlett, GJ; Lawrence, LJ; MacPhee, CE; Sawyer, WH | 1 |
| Amiridze, N; Brown, OR; Dale, WE; Dang, Y | 1 |
| Dyson, HJ; Huntley, JJ; Osborne, MJ; Scrofani, SD; Wright, PE | 1 |
| Liang, JJ | 1 |
| James, MN; Knapp, S; Mark, BL; Triggs-Raine, BL; Vocadlo, DJ; Withers, SG | 1 |
| Hagemeier, J; Hahlbrock, K; Oldham, NJ; Schneider, B | 1 |
| Knaggs, AR | 1 |
| Leclerc, E; Nandi, PK; Nicole, JC; Takahashi, M | 1 |
| Bottomley, SP; Chow, MK; Devlin, GL; Howlett, GJ | 1 |
| Batlle, A; Casas, A; Di Venosa, G; Fukuda, H | 1 |
| Cavagnero, S; Chow, C; Chow, CC; Huppert, TJ; Kimball, EB; Raghunathan, V | 1 |
| Fink, AL; Souillac, PO; Uversky, VN | 1 |
| Ruszkowska, J; Wróbel, JT | 1 |
| Carlsson, K; Carlsson, U; Hammarström, P; Herland, A; Persson, E; Svensson, M; Wiréhn, J | 1 |
| Chatani, E; Goto, Y; Kato, M; Kawai, T; Naiki, H | 1 |
| Bodner, N; Edridge, S; Fink, AL; Hong, DP; Kaylor, J; Yamin, G | 1 |
| He, Y; Luo, Y; Tang, H; Zhou, H | 1 |
| Bottomley, SP; Ellisdon, AM; Thomas, B | 1 |
| Bera, A; Nandi, PK; Sizaret, PY | 1 |
| Glawischnig, E | 1 |
| Daly, SM; Przybycien, TM; Tilton, RD | 1 |
| Chen, YH; Lee, HJ; Pon, YC; Yin, FY; Yu, CM | 1 |
| Bartosz, G; Lewinska, A; Slota, E; Wnuk, M | 1 |
| Akagi, T; Takashima, A; Yoshiike, Y | 1 |
| Chhibber, M; Gupta, S; Sinha, S; Surolia, A | 1 |
| Jain, NK; Roy, I | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Abraham, EC; Datta, P; Kallur, L | 1 |
| Eisenreich, W; Glawischnig, E; Rauhut, T; Spiteller, M; Spiteller, P | 1 |
| Bartucci, R; Guzzi, R; Pantusa, M; Rizzuti, B; Sportelli, L; Stirpe, A | 1 |
| Ando, Y; Ikemizu, S; Kai, H; Kim, J; Misumi, S; Misumi, Y; Motomiya, Y; Nakamura, M; Ota, K; Saito, S; Shinriki, S; Ueda, M | 1 |
| Bednarek, P; Consonni, C; Doubsky, J; Humphry, M; Mansurova, M; Molina, A; Panstruga, R; Pislewska-Bednarek, M; Sanchez-Vallet, A; Schneider, B; Schulze-Lefert, P; Svatos, A | 1 |
| Juárez, J; Mosquera, V; Taboada, P | 1 |
| Ahmad, B; Chiti, F; Tiribilli, B; Winkelmann, J | 1 |
| Ajit, D; Gallazzi, F; Nichols, MR; Touchette, JC; Williams, LL | 1 |
| Bednarek, P; Consonni, C; Ferrari, S; Francocci, F; Harzen, A; Humphry, M; Panstruga, R; Ver Loren van Themaat, E | 1 |
| Brodmann, T; Bülow, L; Carlomagno, T; Eggert, U; Frank, R; Girbig, AK; Kalesse, M; Malek, NP; Nickeleit, I; Rentsch, A; Sasse, F; Steinmetz, H | 1 |
| Bednarek, P; López, G; Molina, A; Piślewska-Bednarek, M; Ramos, B; Sanchez-Vallet, A; Schulze-Lefert, P | 1 |
| Abulwerdi, GA; Gestwicki, JE; Reinke, AA | 1 |
| Chen, D; Duan, L; Li, Y; Liu, W; Shen, B; Yu, Y; Zhang, Q | 1 |
| D'Amico, M; Foderà, V; Leone, M; Militello, V; Ponzoni, A; Sberveglieri, G; Vetri, V | 1 |
| Arcinas, AJ; Booker, SJ | 1 |
| Bednarek, P; Maddula, RK; Piślewska-Bednarek, M; Schulze-Lefert, P; Svatoš, A; Ver Loren van Themaat, E | 1 |
| Ferreira, ST; Jaureguiberry, MS; Prieto, ED; Ramella, NA; Rimoldi, OJ; Sanchez, SA; Schinella, GR; Tricerri, MA; Vela, ME | 1 |
| Malcolmson, SJ; Walsh, CT; Young, TS | 1 |
| Beets, CA; Dubery, I; Huang, JC; Madala, NE | 1 |
| Komatsu, J; Kuwano, R; Matsunari, I; Ono, K; Samuraki, M; Shima, K; Yamada, M; Yanase, D | 1 |
| Ben-Romano, T; Cooper, I; Farfara, D; Frenkel, D; Gazit, E; Levin, A; Scherzer-Attali, R; Segal, D; Segev-Amzaleg, N; Shalev, DE; Shaltiel-Karyo, R; Trudler, D; Vientrov, M | 1 |
| Bischoff, M; Braus, GH; Braus-Stromeyer, SA; Dröge-Laser, W; Feussner, I; Iven, T; König, S; Lipka, V; Singh, S; Tietze, LF | 1 |
| Dasgupta, S; Ghosh, S; Pandey, NK | 1 |
| Amani, S; Naeem, A | 1 |
| Chang, AA; Grothe, HL; Little, MR; Nelson, EF; Sjogren, PP; Yuan, C | 1 |
| Chen, QH; Li, ZY; Lin, SJ; Yuwen, L; Zhang, FL; Zhao, YL | 1 |
| Brański, P; Pałucha-Poniewiera, A; Pilc, A; Stachowicz, K; Sławińska, A; Wierońska, JM | 1 |
| Alam, T; Iram, A; Khan, JM; Khan, RH; Khan, TA; Naeem, A | 1 |
| Darlington, LG; Forrest, CM; Khalil, OS; McNair, K; Pisar, M; Qasem, S; Stone, TW; Vincenten, MC | 1 |
| Khan, RH; Nusrat, S; Zaidi, FK; Zaidi, N | 1 |
| Alavianmehr, MM; Ghahramani, M; Khoshaman, K; Yousefi, R | 1 |
| Chattopadhyay, K; Ghosh, R; Ghosh, S; Mukherjee, M | 1 |
| Glawischnig, E; Hincha, DK; Mucha, S; Müller, TM; Walther, D | 1 |
| Gershenzon, J; Glawischnig, E; Müller, TM; Peskan-Berghöfer, T; Rausch, T; Reichelt, M; Vilches-Barro, A | 1 |
| Ferrari, GV; García, NA; Gutiérrez, EL; Massad, W; Miskoski, S; Muñoz, V; Natera, J; Paulina Montaña, M | 1 |
| Chaari, A; Chevillot-Biraud, A; Fahy, C; Rholam, M | 1 |
| Hemmateenejad, B; Khoshaman, K; Masoudi, R; Yousefi, R; Zm, SZ | 1 |
| Bamford, DH; Bugai, A; De Brabander, J; Fu, Y; Gaelings, L; Hukkanen, V; Julkunen, I; Kainov, DE; Kuisma, M; Le Goffic, R; Lorey, MB; Marjomäki, V; Matikainen, S; Miller, MS; Nandania, J; Nyman, TA; Paavilainen, H; Saelens, X; Schepens, B; Söderholm, S; Tynell, J; Vande Ginste, L; Velagapudi, V | 1 |
| Cao, H; He, B; Li, L; Liu, X; Lu, J; Tang, L; Wang, Y; Zhang, X; Zhu, D | 1 |
| Asai, S; Belhaj, K; Çevik, V; Cruz-Mireles, N; Halkier, BA; Holub, EB; Jones, JD; Kamoun, S; Kemen, A; Kemen, E; Prince, DC; Rallapalli, G; Schoonbeek, HJ; Schornack, S; Xu, D | 1 |
| Bagnoli, L; Cerra, B; Dolciami, D; Fallarino, F; Fazia, MAD; Gargaro, M; Macchiarulo, A; Puccetti, P; Quintana, FJ; Scalisi, G; Servillo, G | 1 |
| Bianchi, A; Coda Zabetta, G; Fallarini, S; Griglio, A; Massarotti, A; Pirali, T; Schmid, R; Serafini, M; Sorba, G; Torre, E | 1 |
| Begley, TP; Bhandari, DM; Fedoseyenko, D | 1 |
| Bednarek, P; Frerigmann, H; Ishikawa, A; Kaido, M; Kosaka, A; Mise, K; Nishiuchi, T; Ono, E; Pastorczyk, M; Piślewska-Bednarek, M; Suemoto, H; Takano, Y | 1 |
| Collier, ME; Giorgini, F; Scrutton, NS; Zhang, S | 1 |
3 review(s) available for thiazoles and tryptophan
| Article | Year |
|---|---|
The biosynthesis of shikimate metabolites.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Animals; Anthranilate Synthase; Bacteria; Betalains; Catalysis; Chorismate Mutase; Coumarins; Flavonoids; Hydro-Lyases; Indoleacetic Acids; Indoles; Intramolecular Transferases; Lignans; Molecular Structure; Penicillium; Phenylalanine; Phenylpropionates; Phosphorus-Oxygen Lyases; Prephenate Dehydratase; Prephenate Dehydrogenase; Pristinamycin; Pyrrolnitrin; Quaternary Ammonium Compounds; Quinones; Shikimic Acid; Staurosporine; Tannins; Thiazoles; Thyroxine; Tryptophan; Tyrosine; Ubiquinone | 2001 |
Tryptophan-derived sulfur-containing phytoalexins--a general overview.
Topics: Anti-Infective Agents; Indoles; Phytoalexins; Plant Extracts; Plants; Sesquiterpenes; Sulfur; Terpenes; Thiazoles; Thiocarbamates; Tryptophan | 2003 |
Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition?
Topics: Animals; Cognition; COVID-19; Humans; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Neuroprotective Agents; Signal Transduction; Sulfonamides; Thiazoles; Tryptophan | 2021 |
87 other study(ies) available for thiazoles and tryptophan
| Article | Year |
|---|---|
Aminolysis of thiazolinones in manual amino acid sequence analysis. Direct detection of carboxyl, amide, and tryptophan residues in conjunction with the dansyl-edman method.
Topics: Amides; Amino Acid Sequence; Carboxylic Acids; Chemical Phenomena; Chemistry; Dansyl Compounds; Methods; Methylamines; Peptide Fragments; Phenylthiourea; Thiazoles; Tryptophan | 1978 |
[The role of L-tryptophan's promoting factor on tumorgenesis in the urinary bladder. 2. Urinary bladder carcinogenicity of FANFT (initiating factor) and L-tryptophan (promoting factor) in mice (author's transl)].
Topics: Animals; FANFT; Female; Mice; Neoplasms, Experimental; Thiazoles; Tryptophan; Urinary Bladder Neoplasms | 1977 |
Enhancing effect of allopurinol on the induction of bladder cancer in rats by n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Allopurinol; Animals; Carcinoma, Transitional Cell; Cytosol; Drug Synergism; FANFT; Female; Liver; Neoplasms, Experimental; Nitrate Reductases; Rats; Sulfhydryl Compounds; Thiazoles; Time Factors; Tryptophan; Urinary Bladder Neoplasms | 1976 |
Reversal by aromatic amino acids of 2-thiazole-DL-alanine inhibition of Salmonella typhimurium.
Topics: Amino Acids; Cell-Free System; Enzyme Repression; Feedback; Histidine; Hydro-Lyases; Membrane Transport Proteins; Phenylalanine; Salmonella typhimurium; Spectrophotometry; Stereoisomerism; Thiazoles; Tryptophan; Tyrosine | 1973 |
Kinetics of derepression of the tryptophan operon of Escherichia coli and Salmonella typhimurium under different culture conditions.
Topics: Aniline Compounds; Anthranilate Synthase; Culture Media; Enzyme Repression; Escherichia coli; Folic Acid; Genes, Regulator; Histidine; Kinetics; Methionine; Nucleic Acid Hybridization; Operon; Peptide Biosynthesis; RNA, Bacterial; RNA, Messenger; Salmonella typhimurium; Sulfur Radioisotopes; Temperature; Thiazoles; Trimethoprim; Tritium; Tryptophan; Tryptophan Synthase | 1973 |
Increase of brain levels of tryptophan induced by inhibition of dopamine beta-hydroxylase (EC 1.14.2.1).
Topics: Animals; Brain; Cresols; Disulfides; Dopamine beta-Hydroxylase; Hydroxyindoleacetic Acid; Imidazoles; Kinetics; Male; Norepinephrine; Oxazoles; Phenylthiourea; Rats; Serotonin; Thiazoles; Tryptophan | 1973 |
A comparison of the rates of RNA and protein synthesis in Escherichia coli cells partially starved for different amino acids.
Topics: Alanine; Amino Acids; Bacterial Proteins; Butyrates; Depression, Chemical; Escherichia coli; Feedback; Histidine; Keto Acids; Ribosomes; RNA, Bacterial; Thiazoles; Time Factors; Tryptophan | 1968 |
Inhibition by phenylalanine of thiazole biosynthesis in Escherichia coli.
Topics: Depression, Chemical; Escherichia coli; Genetics, Microbial; Mutation; Phenylalanine; Shikimic Acid; Thiamine; Thiazoles; Tryptophan; Tyrosine | 1970 |
Coenzyme interactions. 3. Characteristics of the molecular complexes of thiamine with indole derivatives.
Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Pyrimidines; Spectrophotometry; Thiamine; Thiamine Pyrophosphate; Thiazoles; Tryptamines; Tryptophan; Ultraviolet Rays | 1969 |
Interaction of Wratizolin with serum albumins and its antiproteolytic activity.
Topics: Animals; Cattle; Chromatography, Gel; Chymotrypsin; Dansyl Compounds; Horses; Humans; In Vitro Techniques; Indomethacin; Ovalbumin; Protease Inhibitors; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Thiazoles; Trypsin Inhibitors; Tryptophan; Uric Acid | 1983 |
Mutagenicity evaluation of KB-944, a new calcium antagonist, in the Ames bacterial system.
Topics: Benzothiazoles; Calcium Channel Blockers; Escherichia coli; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Thiazoles; Tryptophan | 1982 |
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder.
Topics: Animals; Cocarcinogenesis; Diet; FANFT; Growth; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Diseases; Urinary Bladder Neoplasms | 1983 |
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
Topics: Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; FANFT; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Neoplasms | 1981 |
Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis.
Topics: Arabidopsis; Caulimovirus; Indoles; Mosaic Viruses; Phytoalexins; Plant Diseases; Plant Extracts; Plant Proteins; Pseudomonas; RNA, Messenger; Sesquiterpenes; Terpenes; Thiazoles; Transcription, Genetic; Tryptophan; Xanthomonas campestris | 1996 |
Induction of Arabidopsis tryptophan pathway enzymes and camalexin by amino acid starvation, oxidative stress, and an abiotic elicitor.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Acetolactate Synthase; Amino Acids; Aminobutyrates; Arabidopsis; Glutamate-Ammonia Ligase; Heat-Shock Response; Herbicides; Indoles; Nitrobenzoates; Oxidative Stress; RNA, Messenger; Salicylates; Salicylic Acid; Thiazoles; Tryptophan | 1998 |
Protein conformer selection by ligand binding observed with crystallography.
Topics: Crystallography, X-Ray; Cytochrome-c Peroxidase; Imidazoles; Kinetics; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Thiazoles; Tryptophan | 1998 |
Biosynthesis of camalexin from tryptophan pathway intermediates in cell-suspension cultures of Arabidopsis.
Topics: Arabidopsis; Ascomycota; Cells, Cultured; Indoles; Kinetics; ortho-Aminobenzoates; Plant Diseases; Thiazoles; Tryptophan | 1998 |
Heat-induced conformational change of human lens recombinant alphaA- and alphaB-crystallins.
Topics: Anilino Naphthalenesulfonates; Benzothiazoles; Circular Dichroism; Crystallins; DNA, Complementary; Fluorescent Dyes; Hot Temperature; Humans; Lens, Crystalline; Molecular Weight; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Tryptophan | 2000 |
Human apolipoprotein C-II forms twisted amyloid ribbons and closed loops.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Apolipoprotein C-II; Apolipoproteins C; Benzothiazoles; Chromatography, Gel; Circular Dichroism; Congo Red; Humans; Microscopy, Electron; Protein Conformation; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Ultracentrifugation | 2000 |
Evidence that kynurenine pathway metabolites mediate hyperbaric oxygen-induced convulsions.
Topics: Animals; Coma; Enzyme Inhibitors; Hyperbaric Oxygenation; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Seizures; Sulfonamides; Thiazoles; Time Factors; Tryptophan | 2000 |
Dynamics of the metallo-beta-lactamase from Bacteroides fragilis in the presence and absence of a tight-binding inhibitor.
Topics: Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Binding, Competitive; Catalysis; Computer Simulation; Enzyme Inhibitors; Metalloproteins; Models, Chemical; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Thermodynamics; Thiazoles; Tryptophan | 2000 |
Interaction between beta-amyloid and lens alphaB-crystallin.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Circular Dichroism; Crystallins; Humans; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Ultraviolet Rays | 2000 |
Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.
Topics: Acetylglucosamine; Aspartic Acid; beta-N-Acetylhexosaminidases; Catalysis; Crystallography, X-Ray; Electrons; Escherichia coli; Gangliosidoses; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Spectroscopy, Fourier Transform Infrared; Streptomyces; Thiazoles; Tryptophan | 2001 |
Accumulation of soluble and wall-bound indolic metabolites in Arabidopsis thaliana leaves infected with virulent or avirulent Pseudomonas syringae pathovar tomato strains.
Topics: Arabidopsis; Arabidopsis Proteins; Cell Wall; Cytochrome P-450 Enzyme System; Cytosol; Flavonoids; Glycosides; Indoles; Kaempferols; Malates; Mixed Function Oxygenases; Phenylpropionates; Plant Leaves; Plant Proteins; Pseudomonas; Quercetin; Solubility; Thiazoles; Tryptophan; Virulence | 2001 |
DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid.
Topics: Amyloid; Anilino Naphthalenesulfonates; Animals; Benzothiazoles; Biopolymers; Birefringence; Circular Dichroism; Congo Red; DNA; Fluorescence; Hydrophobic and Hydrophilic Interactions; Mice; Microscopy, Electron; Peptide Fragments; Prions; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Spectrometry, Fluorescence; Temperature; Thiazoles; Tryptophan | 2002 |
Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization.
Topics: Acids; alpha 1-Antitrypsin; Benzothiazoles; Biopolymers; Buffers; Circular Dichroism; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Serpins; Spectrometry, Fluorescence; Structure-Activity Relationship; Thiazoles; Tryptophan | 2002 |
In vitro photosensitisation of a murine mammary adenocarcinoma cell line with Verteporfin.
Topics: Acridine Orange; Adenocarcinoma; Animals; Apoptosis; Coloring Agents; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fluorescent Dyes; Light; Mammary Neoplasms, Animal; Mice; Microscopy, Fluorescence; Oxygen; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Tumor Cells, Cultured; Verteporfin | 2002 |
Chain length dependence of apomyoglobin folding: structural evolution from misfolded sheets to native helices.
Topics: Animals; Apoproteins; Circular Dichroism; Guanidine; Kinetics; Models, Molecular; Myoglobin; Protein Biosynthesis; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazoles; Tryptophan; Whales | 2003 |
Structural transformations of oligomeric intermediates in the fibrillation of the immunoglobulin light chain LEN.
Topics: Amyloid; Amyloidosis; Anilino Naphthalenesulfonates; Benzothiazoles; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Fluorescence Polarization; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Immunoglobulin Light Chains; Multiple Myeloma; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thiazoles; Tryptophan | 2003 |
Activity, folding, misfolding, and aggregation in vitro of the naturally occurring human tissue factor mutant R200W.
Topics: Amyloid; Anilino Naphthalenesulfonates; Arginine; Benzothiazoles; Extracellular Space; Factor VIIa; Genetic Carrier Screening; Humans; Kinetics; Mutation; Nephelometry and Turbidimetry; Protein Binding; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Substrate Specificity; Thiazoles; Thromboplastin; Tryptophan | 2005 |
Main-chain dominated amyloid structures demonstrated by the effect of high pressure.
Topics: Amyloid; Benzothiazoles; beta 2-Microglobulin; Dialysis; Guanidine; Humans; Hydrostatic Pressure; Protein Conformation; Protein Denaturation; Protein Folding; Thiazoles; Tryptophan | 2005 |
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Tryptophan; Tyrosine | 2005 |
Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin.
Topics: Alanine; Alzheimer Disease; Animals; Benzothiazoles; Cell Survival; Circular Dichroism; Disulfides; Endostatins; Escherichia coli; Fibril-Associated Collagens; Fluorescent Dyes; Glutathione; Hydrogen-Ion Concentration; Light; Microscopy, Atomic Force; Neovascularization, Pathologic; PC12 Cells; Protein Conformation; Protein Structure, Tertiary; Rats; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Tryptophan; Ultraviolet Rays | 2006 |
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step.
Topics: Ataxin-3; Benzothiazoles; Biochemistry; Escherichia coli; Humans; Kinetics; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Protein Binding; Recombinant Proteins; Repressor Proteins; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Ubiquitin | 2006 |
Osmolyte trimethylamine N-oxide converts recombinant alpha-helical prion protein to its soluble beta-structured form at high temperature.
Topics: Anilino Naphthalenesulfonates; Animals; Benzothiazoles; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Endopeptidase K; Fluorescence; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methylamines; Mice; Muramidase; Peptide Fragments; Prions; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Scattering, Radiation; Solubility; Thiazoles; Tryptophan | 2006 |
The role of cytochrome P450 enzymes in the biosynthesis of camalexin.
Topics: Arabidopsis; Cytochrome P-450 Enzyme System; Indoles; Kinetics; Phytoalexins; Sesquiterpenes; Terpenes; Thiazoles; Tryptophan | 2006 |
Aggregation of lysozyme and of poly(ethylene glycol)-modified lysozyme after adsorption to silica.
Topics: Adsorption; Benzothiazoles; Fluorescent Dyes; Kinetics; Muramidase; Polyethylene Glycols; Protein Folding; Protein Structure, Secondary; Silicon Dioxide; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thiazoles; Tryptophan | 2007 |
Kinetic refolding barrier of guanidinium chloride denatured goose delta-crystallin leads to regular aggregate formation.
Topics: Animals; Benzothiazoles; Birds; Chromatography, Gel; Circular Dichroism; Congo Red; delta-Crystallins; Dimerization; Electrophoresis, Polyacrylamide Gel; Guanidine; Kinetics; Microscopy, Electron, Transmission; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Protein Folding; Protein Subunits; Thiazoles; Tryptophan | 2007 |
Total anti-oxidant capacity of cell culture media.
Topics: Antioxidants; Benzothiazoles; Chlorides; Colorimetry; Culture Media; Cysteine; Ferric Compounds; Oxidation-Reduction; Phenolsulfonphthalein; Spectrophotometry; Sulfonic Acids; Thiazoles; Tryptophan; Tyrosine | 2007 |
Surface structure of amyloid-beta fibrils contributes to cytotoxicity.
Topics: Acetylation; Amyloid beta-Peptides; Animals; Benzothiazoles; Carrier Proteins; Cattle; Cell Survival; Cells, Cultured; Fluorescence; Humans; Kidney; Maltose-Binding Proteins; Microscopy, Electron, Transmission; Peptide Fragments; Plaque, Amyloid; Thiazoles; Tryptophan | 2007 |
Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates.
Topics: Amyloidosis; Benzamides; Benzothiazoles; Cell Line; Cell Survival; Cross-Linking Reagents; Drug Design; Fluorescence; Glutaral; Humans; Kinetics; Models, Molecular; Oxadiazoles; Phenyl Ethers; Prealbumin; Protein Denaturation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Thiazoles; Triazoles; Tryptophan | 2007 |
Role of trehalose in moisture-induced aggregation of bovine serum albumin.
Topics: Benzothiazoles; Congo Red; Drug Stability; Drug Storage; Electrophoresis, Polyacrylamide Gel; Excipients; Fluorescent Dyes; Humidity; Protein Denaturation; Serum Albumin, Bovine; Spectrometry, Fluorescence; Thiazoles; Trehalose; Tryptophan | 2008 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
Reversal of chaperone activity loss of glycated alphaA-crystallin by a crosslink breaker.
Topics: alpha-Crystallin A Chain; Cross-Linking Reagents; Glucose-6-Phosphate; Glycation End Products, Advanced; Glycosylation; Humans; Spectrometry, Fluorescence; Thiazoles; Time Factors; Tryptophan | 2008 |
Biosynthetic origin of BE-10988 in Streptomyces sp. BA10988.
Topics: Cysteine; Glucose; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Thiazoles; Tryptophan | 2008 |
Thermally induced denaturation and aggregation of BLG-A: effect of the Cu(2+) and Zn (2+) metal ions.
Topics: Amyloid; Benzothiazoles; Calorimetry, Differential Scanning; Cations, Divalent; Copper; Electron Spin Resonance Spectroscopy; Lactoglobulins; Nephelometry and Turbidimetry; Protein Binding; Protein Conformation; Protein Denaturation; Protein Stability; Spectrometry, Fluorescence; Temperature; Thiazoles; Tryptophan; Zinc | 2008 |
Role of conformational change in the C-terminus of beta2-microglobulin in dialysis-related amyloidosis.
Topics: Amyloidosis; Benzothiazoles; beta 2-Microglobulin; Dialysis; Humans; Hydrogen-Ion Concentration; Microscopy, Electron; Mutation; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Ultrasonics | 2008 |
A glucosinolate metabolism pathway in living plant cells mediates broad-spectrum antifungal defense.
Topics: Arabidopsis; Arabidopsis Proteins; Ascomycota; Cysteine; Cytochrome P-450 Enzyme System; Genes, Plant; Glucosinolates; Glycoside Hydrolases; Indoles; Metabolic Networks and Pathways; Mutation; N-Glycosyl Hydrolases; Plant Diseases; Thiazoles; Thiones; Tryptophan | 2009 |
Existence of different structural intermediates on the fibrillation pathway of human serum albumin.
Topics: Amyloid; Benzothiazoles; Circular Dichroism; Congo Red; Fluorescence; Humans; Hydrogen-Ion Concentration; Kinetics; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Protein Conformation; Protein Folding; Serum Albumin; Spectroscopy, Fourier Transform Infrared; Temperature; Thiazoles; Time Factors; Tryptophan; X-Ray Diffraction | 2009 |
Searching for conditions to form stable protein oligomers with amyloid-like characteristics: The unexplored basic pH.
Topics: Amyloid; Benzothiazoles; Carboxyl and Carbamoyl Transferases; Circular Dichroism; Congo Red; Escherichia coli Proteins; Hydrogen-Ion Concentration; Microscopy, Atomic Force; Models, Molecular; Protein Conformation; Protein Denaturation; Protein Folding; Protein Multimerization; Protein Structure, Quaternary; Spectrometry, Fluorescence; Thiazoles; Trifluoroethanol; Tryptophan | 2010 |
Probing the amyloid-beta(1-40) fibril environment with substituted tryptophan residues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid beta-Peptides; Benzothiazoles; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Spectrometry, Fluorescence; Thiazoles; Tryptophan | 2010 |
Tryptophan-derived metabolites are required for antifungal defense in the Arabidopsis mlo2 mutant.
Topics: Arabidopsis; Arabidopsis Proteins; Botrytis; Chlorophyll; Gene Expression Profiling; Gene Expression Regulation, Plant; Immunity, Innate; Indoles; Metabolome; Mutagenesis, Insertional; Oligonucleotide Array Sequence Analysis; Plant Diseases; Proteome; RNA, Plant; Thiazoles; Tryptophan | 2010 |
Synthesis and biological characterization of argyrin F.
Topics: Alanine; Antineoplastic Agents; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Humans; Kinetics; Peptide Hydrolases; Peptides, Cyclic; Protease Inhibitors; Proteasome Inhibitors; RNA Interference; RNA, Small Interfering; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Tryptophan | 2010 |
Tryptophan-derived secondary metabolites in Arabidopsis thaliana confer non-host resistance to necrotrophic Plectosphaerella cucumerina fungi.
Topics: Arabidopsis; Ascomycota; DNA, Plant; Gene Expression Regulation, Plant; Immunity, Innate; Indoles; Molecular Sequence Data; Mutation; Plant Diseases; Thiazoles; Tryptophan | 2010 |
Quantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.
Topics: Amyloid beta-Peptides; Benzothiazoles; Fluorescent Dyes; Models, Molecular; Spectrometry, Fluorescence; Thiazoles; Tryptophan | 2010 |
Radical-mediated enzymatic carbon chain fragmentation-recombination.
Topics: Binding Sites; Carbon; Catalysis; Chromatography, High Pressure Liquid; Free Radicals; Indoles; Peptides; S-Adenosylmethionine; Substrate Specificity; Thiazoles; Time Factors; Tryptophan | 2011 |
Bovine Serum Albumin protofibril-like aggregates formation: solo but not simple mechanism.
Topics: Animals; Benzothiazoles; Cattle; Hydrogen-Ion Concentration; Kinetics; Protein Conformation; Protein Multimerization; Serum Albumin, Bovine; Static Electricity; Temperature; Thermodynamics; Thiazoles; Tryptophan | 2011 |
Enzymology: Radical break-up, blissful make-up.
Topics: Anti-Bacterial Agents; Catalysis; Enzyme Activation; Enzymes and Coenzymes; Free Radicals; Models, Chemical; S-Adenosylmethionine; Thiazoles; Tryptophan | 2011 |
Conservation and clade-specific diversification of pathogen-inducible tryptophan and indole glucosinolate metabolism in Arabidopsis thaliana relatives.
Topics: Absorption; Amino Acid Sequence; Arabidopsis; Ascomycota; Botrytis; Brassicaceae; Genetic Variation; Glucosinolates; Immunity, Innate; Indoles; Molecular Sequence Data; Phylogeny; Plant Diseases; Plant Proteins; Sequence Homology, Amino Acid; Species Specificity; Thiazoles; Tryptophan; Ultraviolet Rays | 2011 |
Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis.
Topics: Amyloid; Anilino Naphthalenesulfonates; Animals; Apolipoprotein A-I; Atherosclerosis; Benzothiazoles; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Heparin; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Matrix Metalloproteinase 12; Neutrophil Activation; Oxidation-Reduction; Protein Binding; Protein Folding; Protein Stability; Protein Structure, Quaternary; Protein Structure, Secondary; Proteolysis; Solvents; Tetradecanoylphorbol Acetate; Thiazoles; Tryptophan | 2011 |
Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks.
Topics: Histidine; Oxazoles; Proline; Protein Processing, Post-Translational; Proteins; Pyridines; Thiazoles; Tryptophan | 2012 |
Activation of camalexin biosynthesis in Arabidopsis thaliana in response to perception of bacterial lipopolysaccharides: a gene-to-metabolite study.
Topics: Arabidopsis; Burkholderia cepacia; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Plant; Genes, Plant; Host-Pathogen Interactions; Indoles; Lipopolysaccharides; Metabolome; Phytoalexins; Plant Diseases; Principal Component Analysis; Sesquiterpenes; Thiazoles; Transcription, Genetic; Transcriptional Activation; Tryptophan; Tryptophan Synthase; Up-Regulation | 2012 |
Imaging findings of familial dementia with a tau R406W mutation.
Topics: Aged; Aniline Compounds; Arginine; Dementia; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Male; Mutation; Positron-Emission Tomography; tau Proteins; Thiazoles; Tryptophan | 2011 |
Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Benzothiazoles; Blood-Brain Barrier; Brain Chemistry; Cognition; Drosophila; Fluorescent Dyes; Humans; Longevity; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Models, Molecular; Motor Activity; Naphthalenes; Neurofibrils; Neuroprotective Agents; Psychomotor Performance; Recognition, Psychology; Thiazoles; Tryptophan | 2012 |
Transcriptional activation and production of tryptophan-derived secondary metabolites in arabidopsis roots contributes to the defense against the fungal vascular pathogen Verticillium longisporum.
Topics: Arabidopsis; Glucosinolates; Indoles; Oligonucleotide Array Sequence Analysis; Plant Diseases; Plant Roots; Stress, Physiological; Thiazoles; Transcription, Genetic; Transcriptional Activation; Tryptophan; Verticillium | 2012 |
(-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme.
Topics: Alkalies; Animals; Benzothiazoles; Catechin; Chickens; Circular Dichroism; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Microscopy, Fluorescence; Muramidase; Nephelometry and Turbidimetry; Protein Structure, Secondary; Salts; Thiazoles; Time Factors; Tryptophan | 2013 |
Detection and analysis of amorphous aggregates and fibrils of cytochrome c in the presence of phenolic acids.
Topics: Animals; Antioxidants; Benzothiazoles; Coumaric Acids; Cytochromes c; Fluorescent Dyes; Gallic Acid; Horses; Microscopy, Fluorescence; Multiprotein Complexes; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; Protein Structure, Secondary; Proteostasis Deficiencies; Single-Cell Analysis; Thiazoles; Tryptophan | 2013 |
Altered protein conformation and lower stability of the dystrophic transforming growth factor beta-induced protein mutants.
Topics: Anilino Naphthalenesulfonates; Benzothiazoles; Circular Dichroism; Corneal Dystrophies, Hereditary; Extracellular Matrix Proteins; Humans; Mutant Proteins; Protein Conformation; Protein Stability; Proteolysis; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles; Transforming Growth Factor beta; Tryptophan | 2013 |
The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89.
Topics: Amino Acid Sequence; Animals; Aromatic-L-Amino-Acid Decarboxylases; Bacillus; Decarboxylation; Dysidea; Molecular Sequence Data; Peptide Synthases; Phenylalanine; Sequence Alignment; Thiazoles; Tryptamines; Tryptophan | 2013 |
The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent.
Topics: Animals; Antidepressive Agents; Citalopram; Diet; Excitatory Amino Acid Antagonists; Fenclonine; Fluoxetine; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Receptors, Kainic Acid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Thiazoles; Tryptophan | 2014 |
Molten globule of hemoglobin proceeds into aggregates and advanced glycated end products.
Topics: Animals; Benzothiazoles; Cattle; Circular Dichroism; Congo Red; Glycation End Products, Advanced; Glycosylation; Glyoxal; Hemoglobins; Microscopy, Electron, Scanning; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thiazoles; Time Factors; Tryptophan | 2013 |
Modified neocortical and cerebellar protein expression and morphology in adult rats following prenatal inhibition of the kynurenine pathway.
Topics: Animals; Cerebellum; Dendrites; Doublecortin Protein; Embryonic Development; Female; Gene Expression Regulation; Hippocampus; Kynurenine; Kynurenine 3-Monooxygenase; Neocortex; Nerve Tissue Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sulfonamides; Synaptic Transmission; Thiazoles; Tryptophan | 2014 |
pH-dependent differential interacting mechanisms of sodium dodecyl sulfate with bovine serum fetuin: a biophysical insight.
Topics: Animals; Benzothiazoles; Calorimetry; Cattle; Circular Dichroism; Fetuins; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Transmission; Nephelometry and Turbidimetry; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Static Electricity; Thermodynamics; Thiazoles; Tryptophan | 2014 |
The impact of calcium ion on structure and aggregation propensity of peroxynitrite-modified lens crystallins: new insights into the pathogenesis of cataract disorders.
Topics: Animals; Benzothiazoles; Calcium; Cattle; Crystallins; Hydrophobic and Hydrophilic Interactions; Lens, Crystalline; Oxidants; Peroxynitrous Acid; Protein Aggregates; Protein Carbonylation; Protein Stability; Proteolysis; Spectrometry, Fluorescence; Thiazoles; Tryptophan; Tyrosine | 2015 |
pH-induced structural change of a multi-tryptophan protein MPT63 with immunoglobulin-like fold: identification of perturbed tryptophan residue/residues.
Topics: Acrylamide; Amino Acid Motifs; Anilino Naphthalenesulfonates; Bacterial Proteins; Benzothiazoles; Cloning, Molecular; Escherichia coli; Fluorescent Dyes; Gene Expression; Hydrogen Bonding; Hydrogen-Ion Concentration; Immunoglobulins; Molecular Sequence Data; Mycobacterium tuberculosis; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Fluorescence; Static Electricity; Thermodynamics; Thiazoles; Tryptophan; Tyrosine | 2015 |
Substantial reprogramming of the Eutrema salsugineum (Thellungiella salsuginea) transcriptome in response to UV and silver nitrate challenge.
Topics: Biosynthetic Pathways; Brassicaceae; Cellular Reprogramming; Gene Expression Regulation, Plant; Gene Knockout Techniques; Glucosinolates; Indoles; Metals, Heavy; Phytoalexins; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Silver Nitrate; Stress, Physiological; Thiazoles; Transcription Factors; Transcription, Genetic; Transcriptome; Tryptophan; Ultraviolet Rays | 2015 |
Sustained exposure to abscisic acid enhances the colonization potential of the mutualist fungus Piriformospora indica on Arabidopsis thaliana roots.
Topics: Abscisic Acid; Arabidopsis; Basidiomycota; Ethylenes; Gene Expression Regulation, Plant; Immunity, Innate; Indoles; Naphthalenes; Osmotic Pressure; Plant Roots; Stress, Physiological; Sulfonamides; Symbiosis; Thiazoles; Tryptophan | 2015 |
Scavenging of photogenerated ROS by Oxicams. Possible biological and environmental implications.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Free Radical Scavengers; Light; Meloxicam; Oxidation-Reduction; Photolysis; Piroxicam; Pyridines; Reactive Oxygen Species; Rhodamines; Riboflavin; Singlet Oxygen; Superoxides; Thiazines; Thiazoles; Tryptophan; Tyrosine; Water Pollutants, Chemical | 2015 |
Insights into Kinetics of Agitation-Induced Aggregation of Hen Lysozyme under Heat and Acidic Conditions from Various Spectroscopic Methods.
Topics: Acrylamide; Amyloid; Animals; Benzothiazoles; Chickens; Chromatography, High Pressure Liquid; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Light; Microscopy, Atomic Force; Muramidase; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Scattering, Radiation; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Thiazoles; Time Factors; Tryptophan | 2015 |
The structural alteration and aggregation propensity of glycated lens crystallins in the presence of calcium: Importance of lens calcium homeostasis in development of diabetic cataracts.
Topics: Animals; Benzothiazoles; Calcium; Cataract; Cattle; Chymotrypsin; Circular Dichroism; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Dynamic Light Scattering; Fluorescence; Glycosylation; Homeostasis; Ions; Kinetics; Lens, Crystalline; Molecular Weight; Protein Aggregates; Protein Conformation; Protein Stability; Proteolysis; Thiazoles; Tryptophan | 2017 |
Regulation of kynurenine biosynthesis during influenza virus infection.
Topics: Animals; Antiviral Agents; Female; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Influenza A Virus, H1N1 Subtype; Interferons; Kynurenine; Lung; Macrophages; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oxazoles; Oximes; Primary Cell Culture; Pyrroles; Sulfonamides; Thiazoles; Transcriptome; Tryptophan; Viral Nonstructural Proteins; Virus Replication | 2017 |
A tryptophan derivative, ITE, enhances liver cell metabolic functions in vitro.
Topics: Alginates; Blotting, Western; Cell Death; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Gene Ontology; Glucuronic Acid; Hexuronic Acids; Humans; Indoles; Liver; Microspheres; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Thiazoles; Tryptophan | 2017 |
Albugo-imposed changes to tryptophan-derived antimicrobial metabolite biosynthesis may contribute to suppression of non-host resistance to Phytophthora infestans in Arabidopsis thaliana.
Topics: Anti-Infective Agents; Arabidopsis; Biomass; Biosynthetic Pathways; Brassica; Disease Resistance; Disease Susceptibility; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Genes, Plant; Glucosinolates; Indoles; Metabolic Networks and Pathways; Mutation; Phytophthora infestans; Plant Diseases; Plant Immunity; Plant Leaves; Reproducibility of Results; Salicylic Acid; Signal Transduction; Thiazoles; Tryptophan; Up-Regulation | 2017 |
Binding Mode and Structure-Activity Relationships of ITE as an Aryl Hydrocarbon Receptor (AhR) Agonist.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Fibroblasts; Histidine; Humans; Immunosuppressive Agents; Indoles; Ligands; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutagenicity Tests; Protein Binding; Receptors, Aryl Hydrocarbon; Structure-Activity Relationship; Thiazoles; Tryptophan | 2018 |
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies.
Topics: Catalytic Domain; Cell Line, Tumor; Drug Discovery; Enzyme Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Molecular Docking Simulation; Molecular Structure; Oximes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tryptophan | 2018 |
Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL).
Topics: Biocatalysis; Carbon-Carbon Lyases; Cloning, Molecular; Crystallography, X-Ray; Enzyme Assays; Molecular Structure; Recombinant Proteins; S-Adenosylmethionine; Thiazoles; Tryptophan | 2018 |
Tryptophan-derived metabolites and BAK1 separately contribute to Arabidopsis postinvasive immunity against Alternaria brassicicola.
Topics: Alternaria; Arabidopsis; Arabidopsis Proteins; Cytochrome P-450 Enzyme System; Disease Resistance; Gene Expression Regulation, Plant; Indoles; Plant Diseases; Protein Serine-Threonine Kinases; Thiazoles; Tryptophan | 2021 |