thiazoles has been researched along with tizoxanide in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 14 (35.90) | 29.6817 |
| 2010's | 17 (43.59) | 24.3611 |
| 2020's | 7 (17.95) | 2.80 |
| Authors | Studies |
|---|---|
| Dubreuil, L; Houcke, I; Mouton, Y; Rossignol, JF | 1 |
| Ballet, JJ; Brasseur, P; Delaunay, A; Favennec, L; Gargala, G; Li, X | 1 |
| Allemon, AM; De Bruyn, S; Gengler, C; Stockis, A | 1 |
| De Bruyn, S; Gengler, C; Rosillon, D; Stockis, A | 1 |
| Dusci, L; Guttner, Y; Marshall, BJ; Viiala, CH; Windsor, HM | 1 |
| Appelbaum, PC; Pankuch, GA | 1 |
| Jung-Cook, H; Ortiz-Plata, A; Palencia, G; Palomares-Alonso, F; Piliado, JC | 1 |
| Cortes, HC; Esposito, M; Hemphill, A; Leitão, A; Mueller, N; Naguleswaran, A | 1 |
| Ayers, MS; Farrar, K; Gaye, K; Korba, BE; Montero, AB; Mukerjee, S; Rossignol, JF | 1 |
| Elazar, M; Glenn, JS; Korba, BE; Lui, P; Rossignol, JF | 1 |
| Fei, C; Qiu, M; Wang, X; Xin, R; Xue, F; Yang, F; Zhang, K; Zhang, L; Zhang, T; Zhao, Z; Zheng, W | 1 |
| Fischer, K; Fischer, PU; Huang, Y; Rao, RU; Weil, GJ | 1 |
| Deplazes, P; Hemphill, A; Kohler, L; Schnyder, M | 1 |
| Chan-Bacab, MJ; Hernández-Núñez, E; Navarrete-Vázquez, G | 1 |
| Chiappa, L; Ciucci, A; La Frazia, S; Rossignol, JF; Santoro, MG | 1 |
| Ballard, TE; Cary, CH; Hoffman, PS; Macdonald, TL; Sifri, CD; Tchouaffi-Nana, F | 1 |
| Fei, C; Meng, X; Wang, M; Wang, X; Xue, F; Zhang, K; Zhang, L; Zhao, Z; Zheng, W | 1 |
| Argotte-Ramos, R; Cedillo-Rivera, R; Chan-Bacab, MJ; Chávez-Silva, F; Hernández-Nuñez, E; Moo-Puc, R; Navarrete-Vazquez, G; Rodríguez-Gutiérrez, Mdel C | 1 |
| Abdel Salam, RA; Emara, S; Hadad, GM | 1 |
| Angeles-Moreno, AP; Contreras-Zavala, L; García-González, A; Maggi-Castellanos, M; Marcelín-Jiménez, G | 1 |
| Andersen, RJ; Anderson, HJ; Av-Gay, Y; Balgi, AD; Forestieri, R; Lam, KK; Nodwell, M; Roberge, M; Vollett, S; Zheng, X | 1 |
| Angelini, M; Arnoldi, F; Belardo, G; Burrone, OR; Ciucci, A; Coira, M; Gianferretti, P; La Frazia, S; Rossignol, JF; Santoro, MG | 1 |
| Ai, N; Welsh, WJ; Wood, RD | 1 |
| Guo, J; Li, Z; Liu, J; Meng, F; Peng, S; Xu, H; Yu, L | 1 |
| Boom, WH; Chervenak, KA; Good, CE; Harausz, EP; Jacobs, MR; Sanchez-Felix, M; Wallis, RS | 1 |
| Agostini, S; Biasin, M; Clerici, M; Gnudi, F; Ibba, SV; Masetti, M; Rossignol, JF; Saulle, I; Trabattoni, D | 1 |
| Biasin, M; Clerici, M; Rossignol, JF; Trabattoni, D | 1 |
| Bhatta, RS; Gupta, A; Misra, A; Tulsankar, SL | 1 |
| Hurt, AC; Oh, DY; Rossignol, JF; Tilmanis, D; van Baalen, C | 1 |
| La Frazia, S; Nicolotti, O; Pedersen, JZ; Piacentini, S; Riccio, A; Rossignol, JF; Santoro, MG; Topai, A | 1 |
| Chang, KO; Chen, S; Dang, W; Ma, B; Pan, Q; Peppelenbosch, MP; Xu, L; Yin, Y | 1 |
| Fei, C; Kong, X; Li, J; Liu, Y; Shou, J; Tang, Y; Wang, C; Wang, M; Wang, X; Xue, F; Zhang, K; Zhang, L | 1 |
| Guo, S; Hai, X; Li, F; Wang, B; Wang, X; Wei, H; Yu, K; Zhao, Y | 1 |
| Cheng, X; Fei, C; Gu, F; Li, J; Liu, Y; Shou, J; Wang, C; Wang, M; Wang, X; Xue, F; Zhang, K; Zhang, L | 1 |
| Barr, IG; Hurt, AC; Koszalka, P; Mifsud, E; Rossignol, JF; Tilmanis, D | 1 |
| He, RZ; Li, XW; Li, Y; Ruan, ZF | 1 |
| Blackburn, K; Brown, DT; Ferreira, DF; Goshe, MB; Migowski, E; Soares, MR; Yamamoto, KA | 1 |
| He, X; Hu, W; Li, X; Meng, F | 1 |
| Costa, D; Diawara, EH; Favennec, L; François, A; Gargala, G; Razakandrainibe, R; Rossignol, JF; Stachulski, AV | 1 |
4 trial(s) available for thiazoles and tizoxanide
| Article | Year |
|---|---|
Nitazoxanide pharmacokinetics and tolerability in man using single ascending oral doses.
Topics: Administration, Oral; Adult; Antiparasitic Agents; Area Under Curve; Food-Drug Interactions; Humans; Male; Maximum Tolerated Dose; Nitro Compounds; Thiazoles | 2002 |
Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g and 1 g b.i.d.
Topics: Administration, Oral; Adult; Antiparasitic Agents; Area Under Curve; Double-Blind Method; Drug Administration Schedule; Half-Life; Humans; Male; Middle Aged; Nitro Compounds; Thiazoles | 2002 |
Nitazoxanide in treatment of Helicobacter pylori: a clinical and in vitro study.
Topics: Adult; Aged; Anti-Infective Agents; Biotransformation; Breath Tests; Drug Therapy, Combination; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Nitro Compounds; Proton Pump Inhibitors; Thiazoles; Urea | 2003 |
Prophylactic and therapeutic efficacy of nitazoxanide against Cryptosporidium parvum in experimentally challenged neonatal calves.
Topics: Animals; Animals, Newborn; Antiparasitic Agents; Cattle; Cryptosporidiosis; Cryptosporidium parvum; Nitro Compounds; Thiazoles | 2009 |
35 other study(ies) available for thiazoles and tizoxanide
| Article | Year |
|---|---|
In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms.
Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Humans; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 1996 |
Efficacy of nitazoxanide, tizoxanide and tizoxanide glucuronide against Cryptosporidium parvum development in sporozoite-infected HCT-8 enterocytic cells.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cryptosporidium parvum; Enterocytes; Glucuronides; Humans; Nitro Compounds; Thiazoles | 2000 |
Activities of tizoxanide and nitazoxanide compared to those of five other thiazolides and three other agents against anaerobic species.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria, Anaerobic; Clindamycin; Metronidazole; Microbial Sensitivity Tests; Nitro Compounds; Thiazoles | 2006 |
Efficacy of nitazoxanide, tizoxanide and tizoxanide/albendazole sulphoxide combination against Taenia crassiceps cysts.
Topics: Albendazole; Animals; Anticestodal Agents; Cysticercosis; Drug Combinations; Drug Synergism; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nitro Compounds; Parasitic Sensitivity Tests; Taenia; Thiazoles | 2007 |
In vitro efficacy of nitro- and bromo-thiazolyl-salicylamide compounds (thiazolides) against Besnoitia besnoiti infection in Vero cells.
Topics: Animals; Antiprotozoal Agents; Cell Adhesion; Chlorocebus aethiops; Host-Parasite Interactions; Microscopy, Electron, Transmission; Nitro Compounds; Parasitic Sensitivity Tests; Sarcocystidae; Thiazoles; Time Factors; Vero Cells | 2007 |
Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication.
Topics: Antiviral Agents; Cell Line; Drug Resistance, Viral; Hepacivirus; Hepatitis Antigens; Hepatitis B virus; Humans; Mutation; Nitro Compounds; Serum; Thiazoles; Virus Replication | 2008 |
Potential for hepatitis C virus resistance to nitazoxanide or tizoxanide.
Topics: Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Nitro Compounds; Recombinant Proteins; Replicon; Ribavirin; Thiazoles; Virus Replication | 2008 |
Liquid chromatography-tandem mass spectrometry analysis of nitazoxanide and its major metabolites in goat.
Topics: Administration, Oral; Animals; Antiparasitic Agents; Chromatography, High Pressure Liquid; Goats; Male; Nitro Compounds; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiazoles | 2008 |
Brugia malayi: Effects of nitazoxanide and tizoxanide on adult worms and microfilariae of filarial nematodes.
Topics: Animals; Antiparasitic Agents; Brugia malayi; Dose-Response Relationship, Drug; Female; Filariasis; Gerbillinae; Male; Microfilariae; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nitro Compounds; Thiazoles | 2009 |
Nitazoxanide, tizoxanide and a new analogue [4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide; NTB] inhibit the growth of kinetoplastid parasites (Trypanosoma cruzi and Leishmania mexicana) in vitro.
Topics: Animals; Antiprotozoal Agents; Benzamides; Humans; Inhibitory Concentration 50; Leishmania mexicana; Molecular Structure; Nitro Compounds; Thiazoles; Trypanosoma cruzi | 2009 |
Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level.
Topics: Animals; Antiparasitic Agents; Antiviral Agents; Cell Membrane; Dogs; HeLa Cells; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A virus; Influenza B virus; Influenza, Human; Jurkat Cells; Nitro Compounds; Protein Processing, Post-Translational; Protein Transport; Thiazoles; Virus Assembly | 2009 |
Nitazoxanide inhibits biofilm formation by Staphylococcus epidermidis by blocking accumulation on surfaces.
Topics: Anti-Bacterial Agents; Biofilms; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Nitro Compounds; Staphylococcus epidermidis; Thiazoles; Vancomycin; Zinc | 2010 |
The pharmacokinetics of nitazoxanide active metabolite (tizoxanide) in goats and its protein binding ability in vitro.
Topics: Animals; Antiparasitic Agents; Blood Proteins; Goats; Male; Nitro Compounds; Protein Binding; Thiazoles | 2010 |
Synthesis of benzologues of Nitazoxanide and Tizoxanide: a comparative study of their in vitro broad-spectrum antiprotozoal activity.
Topics: Antiprotozoal Agents; Giardia; Molecular Structure; Nitro Compounds; Plasmodium; Thiazoles; Trichomonas vaginalis | 2011 |
Validated and optimized high-performance liquid chromatographic determination of tizoxanide, the main active metabolite of nitazoxanide in human urine, plasma and breast milk.
Topics: Adult; Antiparasitic Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Milk, Human; Nitro Compounds; Thiazoles | 2012 |
Development of a method by UPLC-MS/MS for the quantification of tizoxanide in human plasma and its pharmacokinetic application.
Topics: Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry; Thiazoles; Young Adult | 2012 |
Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis.
Topics: Antiparasitic Agents; Autophagy; Cell Line; HEK293 Cells; Humans; Macrophages; Mechanistic Target of Rapamycin Complex 1; Monocytes; Multiprotein Complexes; Mycobacterium tuberculosis; NAD(P)H Dehydrogenase (Quinone); Nitro Compounds; Phagosomes; Proteins; Thiazoles; TOR Serine-Threonine Kinases; Tuberculosis | 2012 |
Thiazolides, a new class of antiviral agents effective against rotavirus infection, target viral morphogenesis, inhibiting viroplasm formation.
Topics: Animals; Antiviral Agents; Cell Line; Haplorhini; Humans; Inclusion Bodies, Viral; Microbial Sensitivity Tests; Nitro Compounds; Protein Binding; Rotavirus; Thiazoles; Viral Nonstructural Proteins; Virus Assembly; Virus Replication | 2013 |
Identification of Nitazoxanide as a Group I Metabotropic Glutamate Receptor Negative Modulator for the Treatment of Neuropathic Pain: An In Silico Drug Repositioning Study.
Topics: Animals; Computational Biology; Computer Simulation; Drug Repositioning; Excitatory Amino Acid Antagonists; High-Throughput Screening Assays; Male; Neuralgia; Nitro Compounds; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Sciatic Neuropathy; Structure-Activity Relationship; Thiazoles | 2015 |
Simultaneous quantification of tizoxanide and tizoxanide glucuronide in mouse plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antiparasitic Agents; Chromatography, Liquid; Glucuronides; Limit of Detection; Male; Mice; Mice, Inbred ICR; Nitro Compounds; Tandem Mass Spectrometry; Thiazoles | 2016 |
Activity of nitazoxanide and tizoxanide against Mycobacterium tuberculosis in vitro and in whole blood culture.
Topics: Antitubercular Agents; Blood Culture; Dose-Response Relationship, Drug; Humans; Mycobacterium tuberculosis; Nitro Compounds; Protein Binding; Serum Albumin; Serum Albumin, Human; Serum Bactericidal Test; Thiazoles; Time Factors | 2016 |
Thiazolides Elicit Anti-Viral Innate Immunity and Reduce HIV Replication.
Topics: Antiviral Agents; Cytochrome P-450 Enzyme System; Gene Expression Regulation; HIV Core Protein p24; HIV-1; Humans; Immunity, Innate; In Vitro Techniques; Leukocytes, Mononuclear; Thiazoles; Virus Replication | 2016 |
Immune correlates of protection against HIV infection and how to elicit them.
Topics: AIDS Vaccines; Animals; Anti-Infective Agents; Cells, Cultured; Female; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Immunity, Mucosal; Immunization; Inflammation Mediators; Interferon Type I; Leukocytes, Mononuclear; RNA, Messenger; Signal Transduction; Thiazoles; Virus Replication | 2017 |
Pharmacokinetics, Metabolism, and Partial Biodistribution of "Pincer Therapeutic" Nitazoxanide in Mice following Pulmonary Delivery of Inhalable Particles.
Topics: Administration, Inhalation; Animals; Chromatography, High Pressure Liquid; Dry Powder Inhalers; Half-Life; Lactic Acid; Lung; Macrophages, Alveolar; Male; Mice; Nitro Compounds; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tandem Mass Spectrometry; Thiazoles; Tissue Distribution | 2017 |
The susceptibility of circulating human influenza viruses to tizoxanide, the active metabolite of nitazoxanide.
Topics: Animals; Antiviral Agents; Cell Survival; Dogs; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Lethal Dose 50; Madin Darby Canine Kidney Cells; Neuraminidase; Neutralization Tests; Nitro Compounds; Reproducibility of Results; Sensitivity and Specificity; Thiazoles | 2017 |
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57.
Topics: A549 Cells; Animals; Binding Sites; Humans; Nitro Compounds; Oxidoreductases; Paramyxoviridae; Paramyxoviridae Infections; Protein Disulfide-Isomerases; Protein Folding; Protein Transport; Thiazoles; Viral Fusion Proteins; Virus Replication | 2018 |
Nitazoxanide Inhibits Human Norovirus Replication and Synergizes with Ribavirin by Activation of Cellular Antiviral Response.
Topics: Antiviral Agents; Caco-2 Cells; Caliciviridae Infections; Cell Line; Cell Line, Tumor; Drug Synergism; Gastroenteritis; HEK293 Cells; Humans; Interferon Regulatory Factor-1; Intestines; Janus Kinases; Nitro Compounds; Norovirus; Organoids; Replicon; Ribavirin; STAT1 Transcription Factor; Thiazoles; Virus Replication | 2018 |
Tizoxanide Inhibits Inflammation in LPS-Activated RAW264.7 Macrophages via the Suppression of NF-κB and MAPK Activation.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitrogen Oxides; RAW 264.7 Cells; Thiazoles | 2019 |
Analysis of tizoxanide, active metabolite of nitazoxanide, in rat brain tissue and plasma by UHPLC-MS/MS.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Limit of Detection; Linear Models; Male; Nitro Compounds; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Thiazoles; Tissue Distribution | 2020 |
Tizoxanide induces autophagy by inhibiting PI3K/Akt/mTOR pathway in RAW264.7 macrophage cells.
Topics: Animals; Anti-Infective Agents; Apoptosis; Autophagy; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Macrophages; Mice; Molecular Structure; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RAW 264.7 Cells; Structure-Activity Relationship; Thiazoles; TOR Serine-Threonine Kinases | 2020 |
Host-targeted nitazoxanide has a high barrier to resistance but does not reduce the emergence or proliferation of oseltamivir-resistant influenza viruses in vitro or in vivo when used in combination with oseltamivir.
Topics: Animals; Antiviral Agents; Cell Proliferation; Dogs; Drug Resistance, Viral; Drug Therapy, Combination; Female; Ferrets; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Male; Nitro Compounds; Orthomyxoviridae Infections; Oseltamivir; Thiazoles | 2020 |
Tizoxanide mitigates inflammatory response in LPS-induced neuroinflammation in microglia via restraining p38/MAPK pathway.
Topics: Animals; Cell Survival; Cells, Cultured; Female; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Microglia; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Pregnancy; Thiazoles | 2020 |
Quantitative proteomic analysis of the tizoxanide effect in vero cells.
Topics: Animals; Anti-Infective Agents; Chlorocebus aethiops; Fatty Acid Synthases; Proteome; Ribonucleoproteins; Thiazoles; Vero Cells | 2020 |
Design, Synthesis, and Pharmacokinetic Evaluation of O-Carbamoyl Tizoxanide Prodrugs.
Topics: Animals; Antiparasitic Agents; Antiviral Agents; Mice; Nitro Compounds; Prodrugs; Thiazoles | 2022 |
Systemic efficacy on
Topics: Animals; Cattle; Cell Line; Cell Survival; Cryptosporidiosis; Cryptosporidium parvum; Dose-Response Relationship, Drug; Esters; Feces; Female; Gerbillinae; Ileum; Inhibitory Concentration 50; Male; Molecular Structure; Prodrugs; Thiazoles | 2021 |