Page last updated: 2024-08-21

thiazoles and thromboxane b2

thiazoles has been researched along with thromboxane b2 in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (8.70)	18.7374
1990's	10 (21.74)	18.2507
2000's	23 (50.00)	29.6817
2010's	9 (19.57)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bruneau, P; Crawley, GC; Edwards, MP; Foster, SJ; Girodeau, JM; Kingston, JF; McMillan, RM	1
Benveniste, J; Coëffier, E; Desquand, S; Floch, A; Lefort, J; Maridonneau-Parini, I; Randon, J; Sedivy, P; Vargaftig, BB	1
Adachi, M; Imai, T; Kamiya, I; Kobayashi, H; Nishikata, H; Okazawa, A; Satoh, H; Takahashi, T; Yamaguchi, H	1
Robertson, DN; Smith, GM	1
Handley, DA; Saunders, RN; Van Valen, RG	1
Hsyu, PH; Koets, MD; Luderer, JR	1
Hibi, S; Inoue, T; Kawahara, T; Kobayashi, N; Murakami, M; Numata, H; Okamoto, Y; Oketani, K; Shinoda, M; Tagami, K	1
Albert, DH; Carter, GW; Grossman, JE; Kruse-Elliott, KT; Summers, JB; Zimmerman, JJ	1
Frölich, JC; Stichtenoth, DO; Wagner, B	1
Fenner, H	1
Brune, K; Geisslinger, G; Krebs, S; Lötsch, J; Muth-Selbach, U; Tegeder, I	1
Di Giamberardino, M; Panara, MR; Patrignani, P; Patrono, C; Renda, G; Rotondo, MT; Santini, G; Sciulli, MG; Seta, F; Tacconelli, S	1
Arakida, Y; Honda, K; Miyata, K; Ohga, K; Suwa, K; Yamada, T; Yokota, M	1
de Meijer, A; de Metz, M; Novakova, I; Thomas, C; Verbruggen, B; Vollaard, H	1
Geisslinger, G; Gühring, H; Neupert, W; Tegeder, I	1
Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M	1
Carballosa Coré-Bodelier, VM; Van Delft, JL; van Haeringen, NJ; van Sorge, AA	1
Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K	1
Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C	1
Chang, DM; Hsieh, TC; Hsu, CT; Kuo, SY; Young, TH	1
Harada, K; Inoue, T; Nagakura, N; Oketani, K	1
Inoue, T; Murakami, M; Oketani, K	1
Goto, T; Ochi, T	1
Kalsbeek-Batenburg, EM; Knijff-Dutmer, EA; Koerts, J; van de Laar, MA	1
Murakami, M; Murota, M; Oketani, K; Sakai, H; Suzuki, T; Takeguchi, N; Uchiumi, T	1
de Metz, M; Hovestad-Witterland, AH; van Kraaij, DJ; Vollaard, EJ	1
Gagnier, RP; Rinder, HM; Souhrada, M; Tracey, JB; Wang, C; Wood, CC	1
Budsberg, SC; Harmon, BG; Jones, CJ; Streppa, HK	1
Al-Awadi, FM; Anim, JT; Haridas, S; Khan, I; Thomas, N	1
Alcaro, S; De Luca, G; Maccari, R; Miceli, N; Monforte, F; Monforte, MT; Ortuso, F; Ottanà, R; Taviano, MF; Trovato, A; Vigorita, MG	1
Ashton, S; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C; Tempel, G; Teti, G; Zingarelli, B	1
Feifel, U; Hanft, G; Kink-Eiband, M; Kuritsch, I; Pairet, M; Trummlitz, G; Van Ryn, J; Wallenstein, G	1
Giraudel, JM; Lees, P; Toutain, PL	1
Beretta, C; Cavalli, M; Garavaglia, G	1
Friton, GM; Schmidt, H; Schrödl, W	1
Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E	1
Bertilsson, L; Hynninen, VV; Korhonen, T; Kurkinen, KJ; Laine, K; Neuvonen, PJ; Olkkola, KT	1
Borer, L; Jung, M; King, JN; Lees, P; Rudaz, C; Seewald, W	1
Langston, VC; Lunsford, KV; Mackin, AJ; McLaughlin, RM; Mullins, KB; Pinchuk, LM; Thomason, JM; Wills, RW	1
Al-Nadaf, S; Brainard, BM; Budsberg, SC; Cathcart, CJ; Reynolds, LR	1
Abe, S; Honma, S; Mitazaki, S; Nakamura, K; Shinohara, M; Takahashi, N; Yoshida, M	1
Bae, JW; Byeon, JY; Choi, CI; Jang, CG; Lee, HI; Lee, SY; Lee, YJ	2
Fet, N; Hata, K; Klinge, U; Minor, T; Nakajima, A; Okamura, Y; Taura, K; Tolba, RH; Uchinami, H; Yamamoto, Y; Yamaoka, Y; Yonezawa, K	1
Suarez-Kurtz, G	1
Alexandre, EM; Antunes, E; Lescano, CH; Mendes-Silvério, CB; Mónica, FZ	1

Reviews

1 review(s) available for thiazoles and thromboxane b2

Article	Year
Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles. Seminars in arthritis and rheumatism, 1997, Volume: 26, Issue:6 Suppl 1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Substrate Specificity; Thiazines; Thiazoles; Thromboxane B2	1997

Article

Year

Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles.

Seminars in arthritis and rheumatism, 1997, Volume: 26, Issue:6 Suppl 1

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Substrate Specificity; Thiazines; Thiazoles; Thromboxane B2

1997

Trials

14 trial(s) available for thiazoles and thromboxane b2

Article	Year
Pharmacokinetics and cyclooxygenase inhibition of itazigrel in normal volunteers after single oral doses. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukotriene B4; Male; Middle Aged; Single-Blind Method; Thiazoles; Thromboxane B2	1994
Effects of meloxicam and indomethacin on cyclooxygenase pathways in healthy volunteers. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1997, Volume: 45, Issue:2 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Indomethacin; Meloxicam; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Therapeutic Equivalency; Thiazines; Thiazoles; Thromboxane B2	1997
Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1 Topics: Adult; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Isoenzymes; Male; Meloxicam; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Thiazines; Thiazoles; Thromboxane B2	1999
Meloxicam, 15 mg/day, spares platelet function in healthy volunteers. Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Male; Meloxicam; Platelet Aggregation; Radioimmunoassay; Reference Values; Thiazines; Thiazoles; Thromboxane B2; Time Factors	1999
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. Journal of clinical pharmacology, 2000, Volume: 40, Issue:10 Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2	2000
Endoscopic comparison of the gastroduodenal safety and the effects on arachidonic acid products between meloxicam and piroxicam in the treatment of osteoarthritis. Clinical rheumatology, 2001, Volume: 20, Issue:2 Topics: Adult; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Digestive System; Dinoprostone; Double-Blind Method; Endoscopy, Digestive System; Female; Gastric Juice; Humans; Leukotriene B4; Male; Meloxicam; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Piroxicam; Safety; Thiazines; Thiazoles; Thromboxane B2	2001
Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis. Rheumatology (Oxford, England), 2002, Volume: 41, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bleeding Time; Blood Platelets; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Meloxicam; Middle Aged; Naproxen; Platelet Aggregation; Random Allocation; Thiazines; Thiazoles; Thromboxane B2	2002
A comparison of the effects of nabumetone vs meloxicam on serum thromboxane B2 and platelet function in healthy volunteers. British journal of clinical pharmacology, 2002, Volume: 53, Issue:6 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Butanones; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Isoenzymes; Male; Meloxicam; Membrane Proteins; Nabumetone; Prostaglandin-Endoperoxide Synthases; Thiazines; Thiazoles; Thromboxane B2	2002
Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. Journal of clinical pharmacology, 2002, Volume: 42, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bleeding Time; Blood Coagulation; Blood Platelets; Double-Blind Method; Female; Hemorrhage; Humans; Indomethacin; Male; Meloxicam; Middle Aged; Partial Thromboplastin Time; Platelet Aggregation; Platelet Count; Prothrombin Time; Thiazines; Thiazoles; Thromboxane B2	2002
Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. Journal of clinical pharmacology, 2004, Volume: 44, Issue:7 Topics: Adult; Aspirin; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Isoenzymes; Male; Meloxicam; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thiazines; Thiazoles; Thromboxane B2	2004
Clinical and anti-inflammatory effects of treating endotoxin-challenged pigs with meloxicam. The Veterinary record, 2006, Oct-21, Volume: 159, Issue:17 Topics: Acute-Phase Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Bacterial; Endotoxemia; Escherichia coli; Escherichia coli Infections; Female; Immunoglobulin G; Lipopolysaccharides; Male; Meloxicam; Single-Blind Method; Swine; Swine Diseases; Thiazines; Thiazoles; Thromboxane B2; Treatment Outcome	2006
Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Blood Coagulation; Cross-Over Studies; Cyclooxygenase 1; Cytochrome P-450 Enzyme System; Drug Interactions; Genotype; Half-Life; Humans; Itraconazole; Male; Meloxicam; Protein Binding; Pyrimidines; Thiazines; Thiazoles; Thromboxane B2; Triazoles; Voriconazole; Young Adult	2009
Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. Veterinary anaesthesia and analgesia, 2012, Volume: 39, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Carbazoles; Dogs; Female; Hemostasis; Meloxicam; Platelet Aggregation; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2	2012
Lack of inhibitory effect of acetylsalicylic acid and meloxicam on whole blood platelet aggregation in cats. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2012, Volume: 22, Issue:1 Topics: Animals; Aspirin; Cats; Cross-Over Studies; Male; Meloxicam; Platelet Aggregation; Thiazines; Thiazoles; Thromboxane B2	2012

Other Studies

31 other study(ies) available for thiazoles and thromboxane b2

Article	Year
(Methoxyalkyl)thiazoles: a new series of potent, selective, and orally active 5-lipoxygenase inhibitors displaying high enantioselectivity. Journal of medicinal chemistry, 1991, Volume: 34, Issue:7 Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Guinea Pigs; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Naphthalenes; Rats; Structure-Activity Relationship; Thiazoles; Thromboxane B2	1991
Pharmacological profile of 48740 R.P., a PAF-acether antagonist. European journal of pharmacology, 1988, Jun-10, Volume: 150, Issue:3 Topics: Animals; Blood Cell Count; Blood Platelets; Bronchodilator Agents; Guinea Pigs; Humans; In Vitro Techniques; Macrophages; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Perfusion; Platelet Activating Factor; Platelet Aggregation; Pulmonary Alveoli; Pyridines; Rabbits; Radioimmunoassay; Superoxides; Thiazoles; Thromboxane B2	1988
[The effect of a specific antagonist of PAF (CV-3988) on airway hyperresponsiveness induced by ozone exposure in beagles]. Arerugi = [Allergy], 1987, Volume: 36, Issue:6 Topics: Animals; Bronchi; Dogs; Female; Methacholine Chloride; Methacholine Compounds; Ozone; Phospholipid Ethers; Platelet Activating Factor; Thiazoles; Thromboxane B2	1987
CV3988 inhibits in vivo platelet aggregation induced by PAF-acether and collagen. European journal of pharmacology, 1986, Apr-09, Volume: 123, Issue:1 Topics: Animals; Blood Pressure; Collagen; Male; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Count; Rabbits; Rats; Species Specificity; Thiazoles; Thromboxane B2; Time Factors	1986
Vascular responses of platelet-activating factor in the Cebus apella primate and inhibitory profiles of antagonists SRI 63-072 and SRI 63-119. Immunopharmacology, 1986, Volume: 11, Issue:3 Topics: Animals; Cebus; Indomethacin; Lung; Macaca mulatta; Male; Papio; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Thrombocytopenia; Thromboxane B2	1986
Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives. Journal of medicinal chemistry, 1994, Sep-16, Volume: 37, Issue:19 Topics: Animals; Blood Platelets; Cells, Cultured; Colitis; Dinoprostone; Disease Models, Animal; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Male; Peritoneal Cavity; Rats; Rats, Inbred F344; Sheep; Structure-Activity Relationship; Thiazoles; Thromboxane B2; Thromboxane-A Synthase	1994
Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist. Shock (Augusta, Ga.), 1996, Volume: 5, Issue:4 Topics: Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Lipopolysaccharides; Lung; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Stroke Volume; Swine; Thiazoles; Thromboxane B2; Vascular Resistance	1996
Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state. Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:5 Topics: Administration, Oral; Adult; Area Under Curve; Cyclooxygenase Inhibitors; Diclofenac; Humans; Male; Meloxicam; Reference Values; Therapeutic Equivalency; Thiazines; Thiazoles; Thromboxane B2	1999
Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3 Topics: Administration, Oral; Animals; Asthma; Chromones; Disease Models, Animal; Guinea Pigs; Immunization, Passive; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Phenylacetates; Receptors, Leukotriene; Receptors, Thromboxane; Serum Albumin, Bovine; Sulfonamides; Tetrazoles; Thiazoles; Thromboxane A2; Thromboxane B2	1999
Effects of selective and unselective cyclooxygenase inhibitors on prostanoid release from various rat organs. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dose-Response Relationship, Drug; Ketorolac; Kidney; Lung; Male; Meloxicam; Nitrobenzenes; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2	2000
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2 Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors	2000
Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Escherichia coli; Flurbiprofen; Humans; Isoenzymes; Lipopolysaccharides; Meloxicam; Membrane Proteins; Monocytes; Ophthalmic Solutions; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thiazines; Thiazoles; Thromboxane B2	2000
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. Journal of leukocyte biology, 2001, Volume: 69, Issue:4 Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha	2001
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3 Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase	2001
Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide. European journal of pharmacology, 2001, Sep-14, Volume: 427, Issue:2 Topics: Animals; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Gastrointestinal Agents; Injections, Intravenous; Intestinal Mucosa; Intestine, Large; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Prednisolone; Pyridines; Rats; Rats, Inbred F344; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase; Time Factors	2001
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. British journal of pharmacology, 2002, Volume: 135, Issue:3 Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Chronic Disease; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Isoenzymes; Membrane Proteins; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Thiazoles; Thromboxane B2	2002
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon. British journal of pharmacology, 2002, Volume: 136, Issue:3 Topics: Animals; Benzothiazoles; Chlorides; Colon; Enzyme Inhibitors; Female; In Vitro Techniques; Intestinal Mucosa; Lipoxygenase Inhibitors; Organic Anion Transporters; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboxane B2; Thromboxane-A Synthase	2002
In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. American journal of veterinary research, 2002, Volume: 63, Issue:11 Topics: Animals; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dog Diseases; Dogs; Gastric Mucosa; Isoenzymes; Male; Meloxicam; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Stifle; Synovial Fluid; Thiazines; Thiazoles; Thromboxane B2	2002
Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam. Scandinavian journal of gastroenterology, 2002, Volume: 37, Issue:12 Topics: Animals; Colitis; Colon; Cyclooxygenase Inhibitors; Dinoprostone; Male; Meloxicam; Oligonucleotides, Antisense; Peroxidase; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiazines; Thiazoles; Thromboxane B2; Tumor Necrosis Factor-alpha	2002
Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. Bioorganic & medicinal chemistry, 2003, Mar-20, Volume: 11, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Models, Molecular; Monocytes; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thiazoles; Thromboxane B2	2003
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. Shock (Augusta, Ga.), 2003, Volume: 20, Issue:1 Topics: Animals; Cells, Cultured; Chromans; Enzyme Activation; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; I-kappa B Proteins; Inflammation Mediators; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinases; Nitric Oxide; Phosphorylation; Prostaglandin D2; Rats; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Staphylococcus aureus; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Troglitazone	2003
Development of in vitro assays for the evaluation of cyclooxygenase inhibitors and predicting selectivity of nonsteroidal anti-inflammatory drugs in cats. American journal of veterinary research, 2005, Volume: 66, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cats; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Inhibitory Concentration 50; Male; Meloxicam; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Radioimmunoassay; Thiazines; Thiazoles; Thromboxane B2	2005
COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacological research, 2005, Volume: 52, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Horses; In Vitro Techniques; Male; Meloxicam; Phenylbutazone; Thiazines; Thiazoles; Thromboxane B2	2005
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2 Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2	2008
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. Research in veterinary science, 2010, Volume: 88, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Etodolac; Isoenzymes; Ketoprofen; Kinetics; Lipopolysaccharides; Meloxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2	2010
Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3 Topics: Animals; Cisplatin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation, Enzymologic; Kidney; Macrophages; Male; Meloxicam; Mice; Mice, Inbred BALB C; Oxidative Stress; Thiazines; Thiazoles; Thromboxane B2	2013
Strongly increased exposure of meloxicam in CYP2C93/3 individuals. Pharmacogenetics and genomics, 2014, Volume: 24, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C9; Genetic Variation; Genotype; Humans; Male; Meloxicam; Metabolic Clearance Rate; Polymorphism, Genetic; Thiazines; Thiazoles; Thromboxane B2	2014
Role of preferential cyclooxygenase-2 inhibition by meloxicam in ischemia/reperfusion injury of the rat liver. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2014, Volume: 53, Issue:1-4 Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Gadolinium; In Situ Nick-End Labeling; Kidney Function Tests; Kupffer Cells; Liver; Liver Diseases; Male; Meloxicam; Rats, Wistar; Reperfusion Injury; Thiazines; Thiazoles; Thromboxane B2; Tumor Necrosis Factor-alpha	2014
Impact of CYP2C93/3 genotype on the pharmacokinetics and pharmacodynamics of oxicam NSAIDs. Pharmacogenetics and genomics, 2014, Volume: 24, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Humans; Male; Thiazines; Thiazoles; Thromboxane B2	2014
Response to Suarez-Kurtz's comments on strongly increased exposure of meloxicam in CYP2C93/3 individuals. Pharmacogenetics and genomics, 2014, Volume: 24, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Humans; Male; Thiazines; Thiazoles; Thromboxane B2	2014
Mirabegron, a β European journal of pharmacology, 2018, Jun-15, Volume: 829 Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Biological Transport; Calcium; Cyclic AMP; Humans; Platelet Aggregation; Receptors, Adrenergic, beta-3; Thiazoles; Thromboxane B2	2018