Page last updated: 2024-08-21

thiazoles and thiostrepton

thiazoles has been researched along with thiostrepton in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's9 (60.00)29.6817
2010's4 (26.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Cundliffe, E; Thompson, J1
Alcaraz, L; Hughes, RA; Moody, CJ; Thompson, SP1
Bella, M; Bulat, S; Nevalainen, M; Nicolaou, KC; Safina, BS; Zak, M1
Aboul-ela, F; Klinck, R; Lentzen, G; Matassova, N; Murchie, AI1
Estrada, AA; Lee, SH; Nicolaou, KC; Safina, BS; Zak, M1
Hang, PC; Honek, JF1
Connell, SR; Fucini, P; Harms, JM; Schluenzen, F; Spahn, CM; Stachelhaus, T; Wilson, DN; Zaborowska, Z1
Kelly, WL; Li, C; Pan, L1
Bhat, UG; Gartel, AL; Halasi, M1
Chen, DY; Cooperman, BS; Leung, GY; Mikolajka, A; Nicolaou, KC; Qin, H; Schwinghammer, K; Starosta, AL; Wilson, DN1
Bhat, UG; Dahari, H; Gartel, AL; Gonzalez, EB; Halasi, M; Lyubimo, AV; Tonetti, DA; Zhao, H1
Gartel, AL; Pandit, B1
Kelly, WL; Zhang, F1
Cox, CL; Doroghazi, JR; Melby, JO; Mitchell, DA; Sokolowski, K; Tietz, JI1
de Vries, RH; Kuipers, OP; Roelfes, G; Viel, JH1

Other Studies

15 other study(ies) available for thiazoles and thiostrepton

ArticleYear
The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism.
    Journal of general microbiology, 1981, Volume: 126, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Escherichia coli; Methylation; Pentoses; Peptide Elongation Factors; Ribosomes; Streptomyces; Thiazoles; Thiostrepton

1981
Biosynthesis inspired Diels-Alder route to pyridines: synthesis of the 2,3-dithiazolylpyridine core of the thiopeptide antibiotics.
    Chemical communications (Cambridge, England), 2002, Aug-21, Issue:16

    Topics: Anti-Bacterial Agents; Pyridines; Serine; Thiazoles; Thiostrepton

2002
Synthetic studies on thiostrepton: construction of thiostrepton analogues with the thiazoline-containing macrocycle.
    Angewandte Chemie (International ed. in English), 2003, Jul-28, Volume: 42, Issue:29

    Topics: Crystallography, X-Ray; Cyclization; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Thiazoles; Thiostrepton

2003
Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
    Chemistry & biology, 2003, Volume: 10, Issue:8

    Topics: Anti-Bacterial Agents; Bacteriocins; Base Sequence; Binding Sites; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Thiazoles; Thiostrepton

2003
Total synthesis of thiostrepton, part 1: construction of the dehydropiperidine/thiazoline-containing macrocycle.
    Angewandte Chemie (International ed. in English), 2004, Sep-27, Volume: 43, Issue:38

    Topics: Macrocyclic Compounds; Molecular Conformation; Piperidines; Thiazoles; Thiostrepton

2004
Electronic structure calculations on the thiazole-containing antibiotic thiostrepton: molecular mechanics, semi-empirical and ab initio analyses.
    Bioorganic & medicinal chemistry letters, 2005, Mar-01, Volume: 15, Issue:5

    Topics: Anti-Bacterial Agents; Electrochemistry; Models, Chemical; Models, Molecular; Molecular Conformation; Thiazoles; Thiostrepton

2005
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
    Molecular cell, 2008, Apr-11, Volume: 30, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Binding Sites; Crystallography, X-Ray; Deinococcus; Gene Expression Regulation; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptides; Protein Biosynthesis; Protein Structure, Tertiary; Ribosomal Proteins; Ribosomes; Thiazoles; Thiostrepton

2008
Thiostrepton biosynthesis: prototype for a new family of bacteriocins.
    Journal of the American Chemical Society, 2009, Apr-01, Volume: 131, Issue:12

    Topics: Anti-Bacterial Agents; Bacteriocins; Chromatography, High Pressure Liquid; Cloning, Molecular; Escherichia coli; Genetic Techniques; Models, Chemical; Models, Genetic; Multigene Family; Open Reading Frames; Peptides; Polymerase Chain Reaction; Streptomyces; Thiazoles; Thiostrepton

2009
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.
    PloS one, 2009, Volume: 4, Issue:5

    Topics: Anti-Bacterial Agents; Apoptosis; Cell Line, Tumor; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Immunoblotting; Peptides; Thiazoles; Thiostrepton

2009
Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays.
    Chemistry & biology, 2009, Oct-30, Volume: 16, Issue:10

    Topics: Anti-Bacterial Agents; Binding Sites; GTP Phosphohydrolases; Peptide Elongation Factor Tu; Peptides, Cyclic; Prodrugs; Protein Biosynthesis; Ribosomes; Thiazoles; Thiostrepton

2009
Thiazole antibiotics against breast cancer.
    Cell cycle (Georgetown, Tex.), 2010, Mar-15, Volume: 9, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Mice; Peptides; Thiazoles; Thiostrepton; Xenograft Model Antitumor Assays

2010
Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells.
    PloS one, 2011, Feb-18, Volume: 6, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; HCT116 Cells; Humans; Neoplasms; Pyrazines; Thiazoles; Thiostrepton

2011
In vivo production of thiopeptide variants.
    Methods in enzymology, 2012, Volume: 516

    Topics: Anti-Bacterial Agents; Genes, Bacterial; Genetic Engineering; Multigene Family; Peptide Biosynthesis; Peptides; Plasmids; Protein Precursors; Ribosomes; Streptomyces; Structure-Activity Relationship; Thiazoles; Thiostrepton

2012
Nucleophilic 1,4-additions for natural product discovery.
    ACS chemical biology, 2014, Sep-19, Volume: 9, Issue:9

    Topics: Actinobacteria; Amino Acids; Anti-Bacterial Agents; Bacteriocins; Biological Products; Computational Biology; Dithiothreitol; Drug Discovery; Drug Evaluation, Preclinical; Ethylamines; Mass Spectrometry; Molecular Structure; Multigene Family; Peptides, Cyclic; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Thiostrepton

2014
Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) via Cu
    Angewandte Chemie (International ed. in English), 2021, 02-19, Volume: 60, Issue:8

    Topics: Alanine; Anti-Bacterial Agents; Boronic Acids; Catalysis; Copper; Enterococcus faecalis; Microbial Sensitivity Tests; Nisin; Protein Processing, Post-Translational; Ribosomes; Solubility; Staphylococcus aureus; Thiazoles; Thiostrepton

2021