Page last updated: 2024-08-21

thiazoles and thiomuracin a

thiazoles has been researched along with thiomuracin a in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (77.78)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Dzink-Fox, J; Gangl, E; Krastel, P; LaMarche, MJ; Leeds, JA; Neckermann, G; Palestrant, D; Patane, MA; Rann, EM; Tiamfook, S; Yu, D1
Brewer, J; Dean, K; Ding, J; Dzink-Fox, J; Gamber, G; Jain, A; Kerrigan, R; Krastel, P; LaMarche, MJ; Lee, K; Leeds, JA; Lombardo, F; McKenney, D; Neckermann, G; Osborne, C; Palestrant, D; Patane, MA; Rann, EM; Robinson, Z; Schmitt, E; Stams, T; Tiamfook, S; Whitehead, L; Yu, D1
Hudson, GA; Mahanta, N; Mitchell, DA; Tietz, JI; van der Donk, WA; Zhang, Z1
Hudson, GA; Mahanta, N; Mitchell, DA; van der Donk, WA; Zhang, Z2
Cogan, DP; Hudson, GA; Mitchell, DA; Nair, SK; Pogorelov, TV; van der Donk, WA; Zhang, Z1
Bogart, JW; Bowers, AA1
Jin, WB; Tang, GL; Wu, S; Xu, YF; Yuan, H1
Suga, H; Vinogradov, AA1

Reviews

2 review(s) available for thiazoles and thiomuracin a

ArticleYear
Recent advances in HemN-like radical S-adenosyl-l-methionine enzyme-catalyzed reactions.
    Natural product reports, 2020, 01-01, Volume: 37, Issue:1

    Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Duocarmycins; Enzymes; Escherichia coli Proteins; Heme; Hydrogen; Methylation; Peptides, Cyclic; Polyketides; Protein Methyltransferases; S-Adenosylmethionine; Thiazoles

2020
Introduction to Thiopeptides: Biological Activity, Biosynthesis, and Strategies for Functional Reprogramming.
    Cell chemical biology, 2020, 08-20, Volume: 27, Issue:8

    Topics: Anti-Bacterial Agents; Biological Products; Gram-Positive Bacteria; Peptides; Peptides, Cyclic; Sulfhydryl Compounds; Thiazoles

2020

Other Studies

7 other study(ies) available for thiazoles and thiomuracin a

ArticleYear
Antibiotic optimization and chemical structure stabilization of thiomuracin A.
    Journal of medicinal chemistry, 2012, Aug-09, Volume: 55, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Crystallography, X-Ray; Enterococcus; Escherichia coli; Escherichia coli Proteins; Female; Gram-Positive Bacterial Infections; Male; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Peptide Elongation Factor Tu; Peptides, Cyclic; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Staphylococcus aureus; Streptococcus pyogenes; Structure-Activity Relationship; Thiazoles; Transcription, Genetic

2012
Antibacterial and Solubility Optimization of Thiomuracin A.
    Journal of medicinal chemistry, 2016, 07-28, Volume: 59, Issue:14

    Topics: Animals; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Peptides, Cyclic; Solubility; Structure-Activity Relationship; Thiazoles

2016
Biosynthetic Timing and Substrate Specificity for the Thiopeptide Thiomuracin.
    Journal of the American Chemical Society, 2016, 12-07, Volume: 138, Issue:48

    Topics: Molecular Conformation; Peptide Synthases; Peptides, Cyclic; Substrate Specificity; Thiazoles

2016
Reconstitution and Substrate Specificity of the Radical S-Adenosyl-methionine Thiazole C-Methyltransferase in Thiomuracin Biosynthesis.
    Journal of the American Chemical Society, 2017, 03-29, Volume: 139, Issue:12

    Topics: Free Radicals; Methyltransferases; Molecular Structure; Peptides, Cyclic; S-Adenosylmethionine; Substrate Specificity; Thiazoles

2017
Structural insights into enzymatic [4+2]
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 12-05, Volume: 114, Issue:49

    Topics: Actinobacteria; Amino Acid Sequence; Antibiosis; Bacterial Proteins; Binding Sites; Biocatalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Cycloaddition Reaction; Models, Molecular; Peptide Synthases; Peptides, Cyclic; Protein Binding; Thiazoles

2017
Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.
    Journal of the American Chemical Society, 2017, 12-27, Volume: 139, Issue:51

    Topics: Anti-Bacterial Agents; Deoxyadenosines; Hydrogen; Methylation; Methyltransferases; Peptides, Cyclic; Protons; S-Adenosylhomocysteine; S-Adenosylmethionine; Solvents; Thiazoles

2017
Thiopeptide Pyridine Synthase TbtD Catalyzes an Intermolecular Formal Aza-Diels-Alder Reaction.
    Journal of the American Chemical Society, 2019, 02-06, Volume: 141, Issue:5

    Topics: Biocatalysis; Cycloaddition Reaction; Molecular Structure; Nitric Oxide Synthase; Peptides; Peptides, Cyclic; Substrate Specificity; Thiazoles

2019