thiazoles has been researched along with thiazolo(3,2-a)perimidine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 12 (80.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, HH; Lin, YO; Liu, KC | 1 |
| Austin, C; Austin, R; Bonnert, R; Cage, P; Christie, J; Christie, M; Dixon, C; Hill, S; Hunt, F; Jewell, R; Martin, I; Robinson, D; Willis, P | 1 |
| Cao, C; Li, X; Li, Y; Liu, Z; Wang, R; Xu, Y; Yu, B; Zhang, X; Zhang, Z; Zhou, B; Zhou, J; Zhou, M | 1 |
| Aertgeerts, K; Arita, T; Hirose, M; Imada, T; Ishikawa, T; Kawamoto, T; Miyazaki, T; Ohashi, T; Okaniwa, M; Sang, BC; Sumita, A; Takagi, T; Tanaka, Y; Tsutsumi, S; Yabuki, M; Yano, J; Yoshida, S | 1 |
| Li, C; Li, Y; Wang, R; Xu, Y; Yu, B; Zhang, Z; Zhou, M | 1 |
| Bharate, SB; Bhushan, S; Guru, SK; Jain, SK; Kour, S; Sharma, PR; Sharma, R; Singh, B; Singh, SK; Vishwakarma, RA | 1 |
| Chen, L; Mahulikar, P; Nandre, J; Patil, S; Patil, U; Patil, V; Prior, T; Redshaw, C; Sahoo, S; Yu, F | 1 |
| Fahmy, H; Kuppast, B | 1 |
| Fu, DJ; Geng, PF; Li, ZH; Liu, HM; Liu, XQ; Ma, JL; Wang, B; Wang, C; Wei, HM; Yu, B; Zhang, J; Zhao, B; Zhao, TQ | 1 |
| Fahmy, H; Kuppast, B; Liapakis, G; Spyridaki, K; Teleb, M | 1 |
| Geng, PF; Li, ZH; Liu, HM; Liu, XQ; Ma, JL; Wang, B; Yu, B; Zhang, J; Zhang, XH; Zhao, B; Zhao, TQ | 1 |
| Bian, X; Huang, X; Huang, Z; Jiao, W; Li, Y; Luo, L; Meng, Y; Sun, L; Sun, Q; Tang, J; Wang, K; Wang, X; Yang, T; Zhang, F | 1 |
| Deng, YH; Liu, JP; Liu, Y; Sun, LP; Xue, WJ; Yan, ZH | 1 |
| Azouz, AA; Bakr, RB; Ghoneim, AA | 1 |
| Cheng, M; Li, R; Wang, H; Wang, J | 1 |
1 review(s) available for thiazoles and thiazolo(3,2-a)perimidine
| Article | Year |
|---|---|
Thiazolo[4,5-d]pyrimidines as a privileged scaffold in drug discovery.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiviral Agents; Chemokines; Drug Discovery; Humans; Molecular Structure; Receptors, Corticotropin-Releasing Hormone; Thiazoles | 2016 |
14 other study(ies) available for thiazoles and thiazolo(3,2-a)perimidine
| Article | Year |
|---|---|
[Synthesis and testing of thiazolo[3,2-a]perimidine for anorectic activity].
Topics: Animals; Appetite Depressants; Mice; Thiazoles | 1983 |
SAR studies on thiazolo[4,5-d]pyrimidine based CXCR2 antagonists involving a novel tandem displacement reaction.
Topics: Animals; Humans; Rats; Receptors, Cytokine; Receptors, Interleukin-8B; Structure-Activity Relationship; Thiazoles | 2007 |
Discovery and development of thiazolo[3,2-a]pyrimidinone derivatives as general inhibitors of Bcl-2 family proteins.
Topics: Binding Sites; Biphenyl Compounds; Drug Evaluation, Preclinical; Molecular Dynamics Simulation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Stereoisomerism; Thiazoles | 2011 |
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Microsomes; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thiazoles; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2012 |
Characterization of the stereochemical structures of 2H-thiazolo[3,2-a]pyrimidine compounds and their binding affinities for anti-apoptotic Bcl-2 family proteins.
Topics: bcl-X Protein; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Kinetics; Molecular Conformation; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Stereoisomerism; Thiazoles | 2013 |
Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2013 |
A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging.
Topics: Cell Line; Cell Survival; Ferric Compounds; Fluorescent Dyes; Hep G2 Cells; Humans; Iron; Limit of Detection; Liver; Microscopy, Fluorescence; Optical Imaging; Spectrometry, Fluorescence; Thiazoles | 2014 |
Identification of thiazolo[5,4-d]pyrimidine derivatives as potent antiproliferative agents through the drug repurposing strategy.
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2017 |
Synthesis of 2-imino and 2-hydrazono thiazolo[4,5-d]pyrimidines as corticotropin releasing factor (CRF) antagonists.
Topics: Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2017 |
Design, synthesis and antiproliferative activity of thiazolo[5,4-d]pyrimidine derivatives through the atom replacement strategy.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2017 |
Design and Synthesis of Novel Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors with the Ability To Rescue Auditory Gating Deficit in Mice.
Topics: Acetylcholine; Administration, Oral; Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Blood-Brain Barrier; Disease Models, Animal; Drug Design; Evoked Potentials; Half-Life; Humans; Mice; Oocysts; Rats; Schizophrenia; Structure-Activity Relationship; Thiazoles; Xenopus laevis | 2019 |
Phenyl and Diaryl Ureas with Thiazolo[5,4-d]pyrimidine Scaffold as Angiogenesis Inhibitors: Design, Synthesis and Biological Evaluation.
Topics: Angiogenesis Inhibitors; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Molecular Structure; Neovascularization, Pathologic; Structure-Activity Relationship; Thiazoles; Urea; Wound Healing | 2019 |
Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Edema; Formaldehyde; Indomethacin; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Sheep; Structure-Activity Relationship; Thiazoles; Ulcer | 2019 |
PB-10, a thiazolo[4,5-d] pyrimidine derivative, targets p21-activated kinase 4 in human colorectal cancer cells.
Topics: Binding Sites; Cell Adhesion; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Drug Design; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Molecular Docking Simulation; p21-Activated Kinases; Protein Kinase Inhibitors; Pyrimidines; RNA Interference; RNA, Small Interfering; Thiazoles | 2020 |