thiazoles has been researched along with thiazolidines in 1248 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 242 (19.39) | 18.7374 |
| 1990's | 385 (30.85) | 18.2507 |
| 2000's | 585 (46.88) | 29.6817 |
| 2010's | 30 (2.40) | 24.3611 |
| 2020's | 6 (0.48) | 2.80 |
| Authors | Studies |
|---|---|
| Levy, L; Ullmann, NM | 1 |
| Singh, DK; Yarbrough, GG | 1 |
| Bönner, G; Ganten, D; Rascher, W; Rockhold, RW; Schaz, K; Unger, T; Vescel, P | 1 |
| Cragoe, EJ; Mandel, LR; Rokach, J; Rooney, CS | 1 |
| Iso, T; Iwao, J; Nishimura, K; Oya, M | 1 |
| Alvarez, I; Gosálvez, M; Vivero, C | 1 |
| Saigot, T | 1 |
| Ficheroulle, X; Macquet, V; Peltier, M; Ta Van, P | 1 |
| Joss, U; Schieweck, K; Schmidt-Ruppin, KH | 1 |
| Freedland, RA; Simpson, RC | 1 |
| Chisari, G; Condorelli, F; di Marco, R; di Mauro, M; Girardello, R; Meroni, PL; Nicoletti, F; Speciale, AM; Uslenghi, C | 1 |
| Coppi, G; D'Adamio, L; Migliorati, G; Nicoletti, I; Riccardi, C | 1 |
| Morita, I; Murota, S; Ochi, H | 1 |
| Bregna, DE; Dunn, RW; Geyer, HM; Hartman, HB; Hrib, NJ; Jurcak, JG; Roehr, JE; Rogers, KL; Rush, DK; Szczepanik, AM | 1 |
| Hatanaka, Y; Kako, Y; Nagao, M; Nukaya, H; Suwa, Y; Toyoda, Y | 1 |
| Buxeraud, J; Comby, F; Lagorce, JF; Raby, C; Thomes, JC | 1 |
| Coppi, G; D'Adamio, F; Migliorati, G; Nicoletti, I; Pagliacci, C; Riccardi, C | 1 |
| Capsoni, F; Girardello, R; Minonzio, F; Ongari, AM; Zanussi, C | 1 |
| Forno, B; Girardello, R; Marinelli, L; Pollono, AM; Pugliese, A; Uslenghi, C | 1 |
| Coppi, G; Falcone, A; Manzardo, S | 2 |
| Auteri, A; Bova, G; Bruni, F; Di Renzo, M; Pasqui, AL; Saletti, M | 1 |
| Aitio, A; Helpiö, E; Kivistö, H; Peltonen, K; Riihimäki, V | 1 |
| Arakawa, N; Otsuka, M; Sakashita, Y; Tsuda, M | 1 |
| Huang, HS; Jurima-Romet, M | 1 |
| Alfano, S; Biolchini, A; Careddu, P; Zavattini, G | 1 |
| Helser, MA; Hotchkiss, JH; Roe, DA | 1 |
| Bauman, PF; Bray, TM; Sikorski, B; Taylor, CG | 1 |
| Deutch, CE | 1 |
| DeMaster, EG; Elberling, JA; Nagasawa, HT; Shirota, FN | 1 |
| Banks, MF; Coloso, RM; Garcia, RA; Stipanuk, MH | 1 |
| Binnaka, T; Fujimura, K; Inoue, K; Kitagawa, S; Kubota, Y; Mizuno, T; Tani, K; Yamaguchi, T | 1 |
| Charyulu, RL; Nagasawa, HT; Roberts, JC; Zera, RT | 1 |
| Imanishi, N; Morooka, S; Uchida, M | 1 |
| Luftig, RB; Macejak, DG | 1 |
| Li, S; Niu, B; Wang, M; Wang, Z; Yu, Y; Zeng, S | 1 |
| Hara, H; Mase, T; Murase, K; Nagaoka, H; Saito, M; Tomioka, K; Yamada, T | 1 |
| Rozmysłowicz, T | 2 |
| Chwiecko, M; Farbiszewski, R; Holownia, A; Pawlowska, D | 1 |
| Meredith, MJ | 1 |
| Astre, C; Joyeux, H; Possompes, B; Recasens, MA; Saint Aubert, B | 1 |
| Ravindranath, V; Shivakumar, BR | 1 |
| Francetic, DJ; Roberts, JC | 1 |
| Hotchkiss, JH; Roe, DA; Shapiro, KB | 1 |
| Rommelspacher, H; Schühle, M; Susilo, R | 1 |
| Yoshimoto, T | 1 |
| Kapás, M; Pudleiner, P; Vereczkey, L | 1 |
| Benslay, DN; Ho, PP; Panetta, JA; Shadle, JK; Towner, RD | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T | 1 |
| Imanishi, N; Komuro, Y; Morooka, S | 1 |
| Xie, JF | 3 |
| Donath, A; Llull, JB; Schifflers, MH; Wermeille, M | 1 |
| Arai, H; Arai, M; Hishinuma, A; Kitamura, K; Kobayashi, T; Kohno, H; Kurakata, S; Nomoto, K; Tomatsu, M | 1 |
| Khoury, MD; Pereira, MA | 1 |
| Calignano, A; Diurno, MV; Mazzoni, O; Piscopo, E | 1 |
| Francetic, DJ; Roberts, JC; Zera, RT | 1 |
| Kurashima, Y; Tsuda, M | 1 |
| Bartsch, H; Béréziat, JC; Calmels, S; Ohshima, H | 2 |
| Chang-Claude, J; Correa, P; Crespi, M; Muñoz, N; Qiu, SL; Raedsch, R; Thurnham, DI; Wahrendorf, J; Yang, GR | 1 |
| Kawabata, T; Tozawa, H | 1 |
| Sen, NP | 1 |
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Clemens, JA; Ho, PP; Panetta, JA | 1 |
| Coloso, RM; Hirschberger, LL; Stipanuk, MH | 1 |
| Jäger, P; Lamme, EK; van Baar, BL; van Duyn, P; van Welie, RT; Vermeulen, NP | 1 |
| Xue, CB; Zhang, DQ; Zhao, YF | 1 |
| Ford, JM; Hait, WN; Yang, JM | 1 |
| Belzer, FO; Boudjema, K; Lindell, SL; Southard, JH | 1 |
| Fujimoto, M; Hirata, M; Ohno, K | 1 |
| Boyd, MR; Ravindranath, V | 1 |
| Aebi, S; Lauterburg, BH; Porta, P; Summer, K | 1 |
| Horie, M; Mase, T; Nagaoka, H; Sakurai, Y; Tomioka, K; Yamada, T | 1 |
| Barchielli, M; Coppi, G | 2 |
| Coppi, G; Del Corona, L; Manzardo, S; Signorelli, G | 1 |
| De Leenheer, AP; Depourcq, GC; Nelis, HJ; Thienpont, LM | 1 |
| Hashimoto, H; Nakashima, M; Satoh, N; Takiguchi, Y | 1 |
| Esumi, H; Ito, Y; Kosaka, H; Kurashima, Y; Terada, N; Tsuda, M; Uozumi, M | 1 |
| van Peteghem, C; van Poucke, L; Vanhoorne, M | 1 |
| Alary, J; Carrera, G; de Saint Blanquat, G; Faurie, M; Lamboeuf, Y; Roumec, C | 1 |
| Deguchi, T; Mataki, Y; Naya, M; Noguchi, M; Yasuda, M | 1 |
| Bragt, PC; Braun, CL; Meuling, WJ | 1 |
| Baker, DH; Chung, TK; Funk, MA | 1 |
| Chung, LY; Khan, L; Schmidt, RJ | 1 |
| Frank, N; Frei, E; Kato, T; Ohgaki, H; Sato, S; Tsuda, M | 1 |
| Ferko, AP | 1 |
| Akagi, R; Taguchi, T; Ubuka, T | 1 |
| Imanishi, N; Komuro, Y; Morooka, S; Uchida, M | 1 |
| DeGraff, W; Friedman, N; Mitchell, JB; Russo, A | 1 |
| Höfle, G; Rommelspacher, H; Susilo, R | 1 |
| Alary, J; Carrera, G; Escrieut, C; Periquet, A | 1 |
| Bässler, KH; Böhler, S; Wagner, K | 1 |
| Benslay, DN; Bertsch, B; Ho, PP; Panetta, JA; Phillips, ML; Towner, RD; Wang, L | 1 |
| Albright, N; DeGraff, WG; Mitchell, JB; Phillips, TL; Rajpal, R; Russo, A | 1 |
| Hatanaka, I; Huitian, Z; Shigeta, Y; Sonobe, M; Terada, M; Yamashita, M; Yasuda, H | 1 |
| Anderson, ME; Bridges, RJ; Meister, A; Underwood, M | 1 |
| Duddy, SK; Hsia, MT | 1 |
| Cooper, JA; Merrill, WW | 1 |
| Kaneto, H; Kojima, M | 1 |
| Alary, J; Anglade, F; Carrera, G; De Saint Blanquat, G; Escrieut, C | 1 |
| Abraham, WM; Ahmed, A; Garrido, R; Stevenson, JS; Tomioka, K | 1 |
| Brodeur, J; Goyal, R; Tardif, R | 1 |
| Bonetti, F; Monafo, V; Nespoli, L; Savio, G; Terracciano, L | 1 |
| Ogata, M; Taguchi, T | 1 |
| Kaplowitz, N; Kuhlenkamp, J; Lu, SC; Robert, A | 1 |
| Abaitua Borda, I; Alexander, LR; Ashley, DL; Bernert, JT; Kilbourne, EM; Patterson, DG; Pendergrast, AH; Posada de la Paz, M | 1 |
| Ashley, DL; Bernert, JT; Grainger, J; Nomura, GS; Patterson, DG; Pendergrast, AH; Vanderveer, D | 1 |
| Brandsma, L; Kammüller, ME; Seinen, W; Terlouw, JK; Verhaar, HJ | 1 |
| Blasberger, D; Kashman, Y; Shochet, NR; Spector, I | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| Black, J; Ip, MM; Shea, WK | 1 |
| Cui, XX | 1 |
| Parthasarathy, R; Ramasubbu, N | 1 |
| Hayakawa, Y; Noguchi, T; Seto, H; Shindo, K; Takenaka, A | 1 |
| del Carmen Guijarro, M; García Cañero, R; López-Alarcón, L; Veloso, JJ | 1 |
| Allen, RG; Farmer, KJ; Newton, RK; Sohal, RS; Toy, PL | 1 |
| Devoto, MA; Puente, J; Sapag-Hagar, M | 1 |
| Ferguson, AE; Kanz, MF; Moslen, MT; Whitehead, RF | 1 |
| Anderson, ME; Meister, A | 2 |
| Chopp, M; Hetzel, FW; Mesina, JE; Page, RH | 1 |
| Hara, H; Kurashima, Y; Miwa, M; Shinohara, K; Tanaka, Y; Tsuda, M | 1 |
| Sheng, BH; Yang, XM; Zhao, DH | 2 |
| Li, XG; Sheng, BH; Yang, XM; Zhao, DH | 1 |
| Kondo, M; Nakano, K; Nishioka, H; Terashima, H; Yoshida, T; Yoshioka, K | 1 |
| Abney, NL; Maatta, EA; Perchellet, EM; Perchellet, JP | 1 |
| Akiguchi, I; Kuriya, N; Miyake, S; Mori, T; Nakanishi, T; Takahashi, A; Toyama, K; Ueda, Y; Yamaguchi, Y; Yokota, A | 1 |
| Furukawa, A; Ikeda, K; Kurono, Y; Li, FL; Takesue, Y | 1 |
| Böhler, S | 1 |
| DeGraff, WG; Mitchell, JB; Russo, A | 1 |
| Harada, T; Hotta, N; Kakuta, H; Kojima, K; Matsubara, H; Mizuno, K; Sakamoto, N; Suzuki, M | 2 |
| Nagao, M; Ohgaki, H; Sugimura, T; Tahira, T; Wakabayashi, K | 1 |
| Harper, BL; Moslen, MT; Roy, D | 1 |
| de Oliveira, CA; Mantovani, B | 1 |
| Borghi, G; Bravi, M; Broglia, M; Guerra, G; Notario, A; Torriani, A | 1 |
| Kwapiszewski, W; Ryzewski, J | 1 |
| Phillips, PG; Tsan, MF | 1 |
| Scoggins, BA; Tresham, JJ; Whitworth, JA | 1 |
| Lang, CA; Richie, JP | 1 |
| Hayes, MA; Kim, HL; Merrill, JC; Murray, CA; Safe, S | 1 |
| Booren, AM; Buckley, DJ; Gray, JI; Ikins, WG; Mandagere, AK; Pearson, AM; Stachiw, MA | 1 |
| Fidelus, RK | 1 |
| Frank, N; Sato, S; Sugimura, T; Tsuda, M | 1 |
| Bielicki, L; Hohorst, HJ; Müller, K; Voelcker, G | 1 |
| Ip, MM; Sylvester, PW; Utz, PJ | 1 |
| Bauman, PF; Bray, TM; Smith, TK | 1 |
| Chiba, Y; Imanishi, T; Kohama, Y; Komiyama, Y; Kuwahara, S; Mimura, T; Miyashita, K; Satake, M; Tanaka, T; Yamamoto, K | 1 |
| Fang, L; Sun, Z; Wu, ZH; Xiao, WW; Xin, H; Xu, SF | 1 |
| Konnerth, A; Orkand, RK | 1 |
| Cellini, F; Cioni, R; Cremonini, C; Fraticelli, G; Giovannini, M; Gusmitta, A; Perri, G; Priolo, U; Spada, E | 1 |
| Ferraris, F; Finiguerra, M; Fraticelli, G; Gallone, F; Morandini, G | 1 |
| Schatten, G; Schatten, H | 1 |
| Carmichael, J; DeGraff, W; Friedman, N; Glatstein, E; Mitchell, JB; Russo, A; Tochner, Z | 1 |
| Brenner, SL; Coué, M; Korn, ED; Spector, I | 1 |
| Klopman, G; Rosenkranz, HS | 1 |
| Masschelein, R; Rosier, J; Van Peteghem, C; Vanhoorne, M; Veulemans, H | 1 |
| Brodeur, J; Goyal, R | 1 |
| Fidelus, RK; Ginouves, P; Lawrence, D; Tsan, MF | 1 |
| Nishina, H; Ohta, J; Ubuka, T | 1 |
| Giorgi, G; Martini, P; Micheli, L; Segre, G | 1 |
| Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT | 1 |
| Bracken, WM; Klaassen, CD | 1 |
| O'Neill, IK; Ohshima, H | 1 |
| Hayashi, T; Ikeda, M; Kuratsune, M; Nagai, A; Sato, S; Sugimura, T; Suzuki, H; Tsuda, M | 1 |
| Bartsch, H; Bourgade, MC; Kamiyama, S; Ohshima, H; Saito, N; Shimada, A; Ziegler, P | 1 |
| Aguilar Barberá, M; Cardesin Castro, R; Peres Serra, J; Reñé Ramírez, R | 1 |
| Anderson, ME; Hwang, O; Meister, A | 1 |
| Fidelus, RK; Tsan, MF | 1 |
| Cline, C; Paweletz, N; Petzelt, C; Schatten, G; Schatten, H; Simerly, C; Spector, I | 1 |
| Kim, HL; Merrill, J; Safe, S | 1 |
| Dierickx, PJ; Vanderwielen, C | 1 |
| Lang, CA; Mills, BJ; Richie, JP | 1 |
| Bonnet, P; De Ceaurriz, J; Gagnaire, F; Simon, P | 1 |
| Alvarez-Noves, J; Alvarez-Rodríguez, Y; Ruano, A; Valladares, Y | 1 |
| Cho, T; Hagihara, Y; Hayashi, S; Kaminishi, H; Tsuno, N | 1 |
| Boettcher, B; Meister, A | 2 |
| Tannenbaum, SR | 1 |
| Fujita, Y; Nagao, M; Ochiai, M; Sugimura, T; Tahira, T; Takayama, S; Wakabayashi, K | 1 |
| Fukasawa, H; Hotta, N; Iida, M; Kakuta, H; Kimura, M; Koh, N; Morimura, T; Sakamoto, N; Terashima, H | 1 |
| Ip, MM; Schenkel, L; Sylvester, PW | 1 |
| Hirayama, T; Kakizoe, T; Niitsuma, J; Sato, S; Sügimura, T; Tsuda, M | 1 |
| Hazelton, GA; Hjelle, JJ; Klaassen, CD | 1 |
| Danis, EH; Del Vecchio, PJ; Rosano, CL; Tsan, MF | 1 |
| DeGraff, WG; Finkelstein, E; Gamson, J; Mitchell, JB; Russo, A; Spiro, IJ | 1 |
| Campbell, L; Jones, AH; Wilson, HK | 1 |
| Dunn, MJ; Ludgin, JR; Ritter, JM; Scharschmidt, LA; Smith, RD | 1 |
| Mitchell, JB; Russo, A | 2 |
| Brugarolas, A; Gosalvez, M | 2 |
| Gosálvez, M | 3 |
| Slater, TF | 1 |
| Sappino, AP; Smith, IE | 1 |
| Caciacli, F; Ciancetta, S; Ciccarelli, R | 1 |
| Coninx, P; Galichet, V; Garbe, E; Jardillier, JC; Nasca, S | 1 |
| Blaine, EH; Seymour, AA | 3 |
| Burdett, K; Elder, JB; Reed, PI; Smith, PL; Walters, CL | 1 |
| Abe, Y; Imanishi, M; Komori, T; Miura, K; Okahara, T; Yamamoto, K; Yukimura, T | 1 |
| Warashina, A | 1 |
| McCarty, MF | 1 |
| Friedman, N; McPherson, S; Mitchell, JB; Russo, A | 1 |
| Chmiel, J; Rybczyńska, M | 1 |
| Feng, GH; Zhao, HP | 1 |
| Funae, Y; Komori, T; Sasaki, D; Yamamoto, K | 1 |
| Bönner, G; Ganten, D; Rascher, W; Rockhold, RW; Schaz, K; Schömig, A; Speck, G; Unger, T | 1 |
| Komori, T; Yamamoto, K | 1 |
| Coppey, J; Magdelenat, H; Rigaud, O | 1 |
| Fujii, S; Hirano, Y; Hirota, A; Sawanobori, T | 1 |
| Albrici, A; Barcellini, W; De Bartolo, G; Froldi, M; Meroni, P; Palmieri, G | 1 |
| Ganguli, BN; Nadkarni, SR; Patel, MV; Reddy, GC; Reden, J | 1 |
| Blaine, EH | 1 |
| Bito, LZ | 1 |
| Hatanaka, I; Kikkawa, R; Kobayashi, N; Morimura, T; Shigeta, Y; Terashima, H; Tsuboshima, M; Yasuda, H | 1 |
| Hatanaka, I; Kikkawa, R; Kobayashi, N; Shigeta, Y; Yasuda, H | 1 |
| Hama, K; Hatanaka, I; Kikkawa, R; Shigeta, Y; Terashima, H; Tsuboshima, M; Yamamoto, R | 1 |
| Grier, RL; Merkley, DF; Roth, JA | 1 |
| Bruggink, JE; Glazenburg, EJ; Mulder, GJ; Wolters-Keulemans, K | 1 |
| Nagao, M; Sugimura, T; Tahira, T; Tsuda, M; Wakabayashi, K | 1 |
| Notario, A; Ranghetti, L; Stanziale, D; Torriani, A; Vitti, MP | 1 |
| Czubak, J; Włodek, L | 1 |
| Cresta, MA; Tiscornia, OM; Tumilasci, O; Waisman, H | 1 |
| Ellen, G; Schuller, PL | 1 |
| Bilmazes, C; Obiedzinski, M; Shuker, DE; Tannenbaum, SR; Wagner, DA; Young, VR | 1 |
| Bartsch, H; Friesen, M; O'Neill, IK; Ohshima, H; Pignatelli, B | 1 |
| Hirayama, T; Kakizoe, T; Sugimura, T; Tsuda, M | 1 |
| Ewen, SW; Helgason, T; Jaffray, B; Outram, JR; Pollock, JR; Stowers, JM | 1 |
| Bartsch, H; Lu, SH; Ohshima, H | 1 |
| Bartsch, H; Cassale, V; Crespi, M; Forichon, J; Lambert, R; Minaire, Y; Muñoz, N; Ohshima, H; Ramazotti, V; Walters, CL | 1 |
| Bartsch, H; Ohshima, H | 1 |
| Ambrus, JL; Bock, FG; Mirand, EA; Pine, MJ | 1 |
| Huertas, A; Smeyers, YG | 1 |
| Bartsch, H; Friesen, M; O'Neill, I; Ohshima, H | 1 |
| Bassleer, R; Desaive, C; Jamoulle, JC; Lapiere, CL; Marnette, JM; Wiliquet, P | 1 |
| Bartsch, H; Crespi, M; Friesen, M; Lu, SH; Muñoz, N; O'Neill, I; Ohshima, H; Pignatelli, B | 1 |
| Groweiss, A; Kashman, Y; Shochet, NR; Spector, I | 1 |
| Hemminki, K | 1 |
| Bailie, MB; Hook, JB; Newton, JF; Smith, JH | 1 |
| Billemont, G; Grosjean, R; Rosier, J; Van de Walle, A; Van Peteghem, C; Vanhoorne, M | 1 |
| Bartsch, H; Béréziat, JC; Friesen, M; O'Neill, IK; Ohshima, H | 1 |
| Fleming, JF; Miquel, J; Weber, HU | 1 |
| Ballard, RC; Binnard, R; Economos, AC; Miquel, J; Philpott, DE | 1 |
| Economos, AC; Fleming, J; Miquel, J | 1 |
| Bicking, JB; Blaine, EH; Bock, MG; Cragoe, EJ; DiPardo, RM; Gould, NP; Holtz, WJ; Lee, TJ; Robb, CM; Smith, RL; Springer, JP | 1 |
| Hirayama, T; Sugimura, T; Tsuda, M | 1 |
| Chanal, JL; Chapat, JP; Fatome, M; Fernandez, JP; Genin, M; Robbe, Y; Sentenac-Roumanou, H | 1 |
| Teyssier, JR | 1 |
| Díaz Gil, JJ; Trilla, C | 1 |
| Blanco, MF; de Paz, E; Gosálvez, M | 1 |
| Meister, A; Williamson, JM | 1 |
| Alexander, P; Dobbie, D; Forbes, P; Powles, R | 1 |
| Boettcher, B; Meister, A; Williamson, JM | 1 |
| Fujii, S; Hirota, A; Kamino, K; Sawanobori, T | 1 |
| Hahn, FE | 1 |
| Young, CW | 1 |
| Eisenberg, MA; Hsiung, SC | 1 |
| Barbieri, A; Boccardo, F; Canobbio, L; Guarneri, D; Merlano, M; Rosso, R | 1 |
| Bickle, QD | 1 |
| Efthymiou, ML; Jouglard, J | 1 |
| Beames, DJ; Campbell, AJ; Edwards, SR; Montague, PE; Moore, RJ; Sheers, M | 1 |
| Blaine, EH; Russo, HF; Schorn, TW; Snyder, C | 1 |
| Henderson, PT; Leijdekkers, CM; Nossent, SM; van Doorn, R | 1 |
| Efthymiou, ML; Fournier, E; Garnier, R | 1 |
| Görler, K; Krumbiegel, G; Mennicke, WH; Siehl, HU | 1 |
| Bassleer, R; De Pauw-Gillet, MC; Jamoulle, JC; Lapiere, CL; Marnette, JM; Massart, B; Wiliquet, P | 1 |
| Billemont, G; Grosjean, R; Rosier, J; Van de Walle, E; Van Peteghem, C; Vanhoorne, M | 1 |
| Banks, AR; Hessek, E; Jones, T; Parks, RC | 1 |
| Faini, D; Pagella, PG; Turba, C | 2 |
| Alberto, P | 1 |
| Huang, ZX; May, PM; Williams, DR | 1 |
| Buzzi, S; Ghetti, C; Sala, G | 2 |
| Armand, JP; Delsol, G; Marty, C; Neulat, I | 1 |
| Fujii, S; Hirota, A; Kamino, K | 1 |
| Raymond, N | 1 |
| Dubini, F; Falchi, M | 1 |
| Lankelma, J; Leyva, A; Penders, PG; Pinedo, HM | 1 |
| Kahn, RS; Manoguerra, AS | 1 |
| Dubini, F; Falchi, M; Nebuloni, R | 1 |
| Delbressine, LP; Henderson, PT; Leijdekkers, CM; van Doorn, R; Vertin, PG | 1 |
| Anders, MW; Stevens, JL | 1 |
| Akaji, K; Aono, M; Fujii, N; Moriga, M; Takagi, A; Yajima, H | 1 |
| Chevrel, B | 1 |
| Dubini, F; Falchi, M; Ferrario, F; Marcucci, A | 1 |
| Carminati, R; Dubini, F; Falchi, M; Ferrario, F; Marcucci, A | 1 |
| Bortolan-Gianese, P; Dubini, F; Falchi, M; Ferrario, F; Marcucci, A | 1 |
| Baruchel, S; Batist, G; Farah, R; Jamali, M; Wang, T | 1 |
| Bandaletova, TY; Bartsch, H; Brouet, I; Kirby, G; Ogunbiyi, F; Ohshima, H; Pipitgool, V; Vatanasapt, V | 1 |
| Annoni, G; Arosio, B; Cullurà, D; Gagliano, N; Santambrogio, D; Uslenghi, C | 1 |
| Ben-Ze'ev, A; Bershadsky, AD; Denisenko, ON; Glück, U; Sklyarova, TV; Spector, I | 1 |
| Czeslick, E; Glaesser, D; Gruner, M; Iwig, M; Müller, A; Spindler, M | 1 |
| Arima, M; Fukuda, T; Makino, S; Manaka, K | 1 |
| Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Lebegue, N; Luyckx, M | 1 |
| Lee, BL; New, AL; Ong, CN; Yang, XF | 1 |
| Esumi, H; Kosaka, H; Kurashima, Y; Ohshima, H; Sugimura, T; Tsuda, M | 1 |
| Grabowska, A; Marcinkiewicz, J; Włodek, L | 1 |
| Bubrick, MP; Carroll, MP; Feeney, DA; Johnston, GR; Roberts, JC; Schlafmann, SE; West, MA; Zera, RT | 1 |
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| de Juan, E; de la Fuente, M; Ferrández, D; Miquel, J; Muñoz, F | 1 |
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| Gerke, V; Kielbassa, K; Schmitz, C | 1 |
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| Hamada, M; Hara, H; Kondo, Y; Mase, T; Nagaoka, H; Saito, M; Suzuki, T; Takahashi, T; Takeuchi, M; Tomioka, K; Yamada, T | 1 |
| Corsi, MM; Ferrero, ME; Fulgenzi, A; Gaja, G; Maes, HH; Wasserman, K | 1 |
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| Adachi, Y; Fukazawa, M; Homma, N; Kuromaru, O; Nishie, I; Suzuki, Y; Tamura, K | 1 |
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| Blanchard, SG; Cobb, JE; Collins, JL; Cooper, JP; Goreham, DM; Holmes, CP; Hull-Ryde, EA; Kliewer, SA; Lehmann, JM; Lenhard, JM; Milburn, MV; Miller, AB; Mohr, CP; Moore, LB; Oberfield, JL; Parks, DJ; Plunket, K; Willson, TM | 1 |
| Howard, J; Surka, M; Trimble, WS; Xie, H | 1 |
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| Fukazawa, T; Hayashi, H; Kato, R; Kiso, Y; Mimoto, T; Misawa, S; Nojima, S; Sato, H; Shintani, M; Takaku, H; Terashima, K; Ueno, T | 1 |
| Angerer, J; Hardt, J; Weiss, T | 1 |
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| Busse, WW; Jansen, KJ; Kennedy, JD; Kita, H; Sedgwick, JB | 1 |
| Hamm-Alvarez, SF; Jerdeva, GV; Kalman, D; Rhodes, CJ; Schechter, JE; Wu, K; Yarber, FA | 1 |
| Fan, H; Lam, DS; Rao, SK; Zhou, YS | 1 |
| Hall, AC; Kerrigan, MJ | 1 |
| Baluska, F; Illes, P; Ismail, A; Lang, I; Lichtscheidl, IK; Ovecka, M | 1 |
| Ayscough, KR | 1 |
| Rizk, RS; Walczak, CE | 1 |
| Dugger, DR; Fellows, J; McDowell, JH; Orisme, W; Peterson, JJ; Shelamer, CL; Smith, WC | 1 |
| Orlando, KA; Pittman, RN; Stone, NL | 1 |
| Aebi, U; Boerries, M; Buchmeier, S; Jockusch, BM; Schoenenberger, CA; Sütterlin, R | 1 |
| Davis, JJ; Dong, F; Fang, B; Guo, W; Inoue, S; Teraishi, F; Wu, S; Zhang, L | 1 |
| Butt, RH; Coorssen, JR; Hibbert, JE | 1 |
| Atkinson, SJ; Hallett, MA; Lam, NG; Ransom, RF; Smoyer, WE | 1 |
| do Carmo, DR; Filho, NL; Gessner, F; Rosa, AH | 1 |
| Dandia, A; Khaturia, S; Loupy, A; Mérienne, C; Morgant, G; Singh, R | 1 |
| del Hierro, I; Fajardo, M; Pérez-Quintanilla, D; Sierra, I | 1 |
| Ben-Ari, Y; Caillard, O; Fattoum, A; Ferhat, L; Medina, I; Pellegrino, C; Rami, G | 1 |
| Che, Y; Marshall, GR | 1 |
| Akopian, A; Cristofanilli, M; Krizaj, D; Szikra, T | 1 |
| Fujino, H; Nohta, H; Yamaguchi, M; Yoshida, H | 1 |
| Bausen, M; Betz, H; Fuhrmann, JC; O'sullivan, GA | 1 |
| Hasenstein, KH; Ma, Z | 1 |
| Foissner, I; Hörmanseder, K; Obermeyer, G | 1 |
| Konák, C; Laga, R; Subr, V; Ulbrich, K | 1 |
| Gao, F; Hu, XF | 1 |
| Bianchi, MG; Bussolati, O; Dall'Asta, V; Gatti, R; Gazzola, GC; Rotoli, BM | 1 |
| Devreotes, PN; Huang, YE; Keizer-Gunnink, I; Loovers, HM; Postma, M; van Haastert, PJ | 1 |
| Amano, A; Inaba, H; Nakagawa, I; Nakanishi, Y; Tsuda, K; Umebayashi, K; Yoshimori, T | 1 |
| Ahmed, S; Hamann, M; Khalifa, S; Mesbah, M; Youssef, D | 1 |
| Crews, P; Johnson, TA; Sonnenschein, RN; Tenney, K; Valeriote, FA | 1 |
| Bengtsson, T; Orselius, K; Wetterö, J | 1 |
| Bonner, M; King, A; Laughlin, RC; McGugan, GC; Powell, RR; Temesvari, LA; Welter, BH | 1 |
| Prasad, SV; Rockman, HA; Volovyk, ZM; Wolf, MJ | 1 |
| Lee, YC; Park, SJ | 1 |
| El Sayed, KA; Marchetti, D; Youssef, DT | 1 |
| Brunskill, NJ; Chana, RS | 1 |
| Genescà, M; Hotter, G; Sola, A | 1 |
| Chen, K; Hatcher, NG; Jakubowski, JA; Kim, WS; Rubakhin, SS; Seif, I; Shih, JC; Squires, LN; Stuart, JN; Sweedler, JV | 1 |
| Cohen, AS; Geddes-Klein, DM; Meaney, DF; Mesfin, MN; Serbest, G | 1 |
| Chang, YC; Ho, YC | 1 |
| Abramovits, W; Boguniewicz, M | 1 |
| Collings, DA; Himmelspach, R; Lill, AW; Wasteneys, GO | 1 |
| Halban, PA; Min, L; Pessin, JE; Tomas, A; Yermen, B | 1 |
| Chan, DW; Ethier, CR; Read, AT | 1 |
| Faria, C; Jacinto, A; Wood, W | 1 |
| Aspengren, S; Wallin, M; Wielbass, L | 1 |
| Kölsch, A; Leube, RE; Windoffer, R; Wöll, S | 1 |
| Davila, A; Faundez, V; Fontanella, B; Gearing, M; Gutekunst, CA; Jimenez, R; Juncos, J; Meroni, G; Ono, S; Procaccio, V; Salazar, G; Sontag, E; Sontag, JM; Styers, ML; Wainer, BH | 1 |
| Hoffmann, EK; Hougaard, C; Klausen, TK; Pedersen, SF | 1 |
| Demuth, HU; Li, L; Zukowska, Z | 1 |
| Harper, MT; Sage, SO | 1 |
| Ali, M; Choudhary, MI; Haq, ZU; Khan, KM; Lodhi, MA; Rahman, AU; Ullah, Z | 1 |
| Gabelt, BT; Kaufman, PL; Kiland, JA; Kim, CB; Miller, CL; Nork, TM; Peterson, J; Ver Hoeve, JN | 1 |
| David-Watine, B; Delbarre, E; Enninga, J; Münter, S; Nehrbass, U; Shorte, SL; Vazquez-Martinez, R | 1 |
| Fiserová, J; Opatrný, Z; Petrásek, J; Schwarzerová, K | 1 |
| Bourne, J; Morgan, JR; Pieribone, VA | 1 |
| Baluska, F; Chen, T; Chen, Y; Guo, Y; Lin, J; Samaj, J; Shen, S; Zheng, M | 1 |
| Jin, SM; Kim, SR; Lee, KS; Lee, YC; Li, L; Min, KH; Park, HS; Park, SJ | 1 |
| Franklin-Tong, VE; Huang, S; Li, S; Staiger, CJ; Thomas, SG | 1 |
| Barak, Y; Cormier, RT; Matise, I; McAlpine, CA | 1 |
| Bourne, HR; Govaerts, C; Hahn, KM; Knight, ZA; Shokat, KM; Van Keymeulen, A; Wong, K | 1 |
| Ampe, C; Dieterle, M; Hoffmann, C; Steinmetz, A; Thomas, C; Van Troys, M | 1 |
| Dalton, JT; Donkor, IO; Guan, N; Korukonda, R; Liu, J | 1 |
| Karpouzas, DG; Menkissoglu-Spiroudi, U; Pantelelis, I; Tsiropoulos, N | 1 |
| Breborowicz, A; Oreopoulos, DG; Podkowka, R; Styszynski, A; Wieczorowska-Tobis, K | 1 |
| Esposito, M; Hemphill, A; Müller, N | 1 |
| Chen, TS; Nagasawa, H; Oz, HS | 1 |
| Fukuyama, T; Han, FS; Tokuyama, H | 1 |
| Aydogan, F; Bagdatli, E; Ocal, N; Turgut, Z; Yolacan, C | 1 |
| Dowell, ML; Lakser, OJ; Mitchell, RW; Solway, J | 1 |
| Dykhuizen, EC; Kiessling, LL; May, JF; Tongpenyai, A | 1 |
| Ludwig, C; Mootz, HD; Schwarzer, D | 1 |
| Choung, SY; Du, XF; Jiang, CZ; Won, EK; Wu, CF | 1 |
| Bai, J; Chen, H; Guo, Z; Jiao, L; Li, X; Yin, Q | 1 |
| Chaturvedi, SC; Pancholi, SS; Sharma, RN; Vasu, KK; Xavier, FP | 1 |
| Betancort, JM; Campbell, DA; Carney, D; Chen, SH; Gordon, E; Hanway, D; Li, X; Liao, W; Liu, J; Liu, R; Schmeits, J; Winn, DT; Xu, Q | 1 |
| Carmi, C; Fu, J; King, AR; Lodola, A; Mor, M; Piomelli, D | 1 |
| Amirthaganesan, S; Aridoss, G; Jeong, YT; Kim, JT; Kim, MS | 1 |
| Badria, FA; Dawood, KM; Hegazi, B; Mohamed, HA | 1 |
| Abele, S; Binkert, C; Bolli, MH; Bravo, R; Buchmann, S; Bur, D; Gatfield, J; Hess, P; Kohl, C; Mangold, C; Mathys, B; Menyhart, K; Müller, C; Nayler, O; Scherz, M; Schmidt, G; Sippel, V; Steiner, B; Strasser, D; Treiber, A; Weller, T | 1 |
| Jiao, XZ; Liu, XY; Wang, LP; Wu, Q; Xiao, Q; Xie, P | 1 |
| Beck, B; Cellitti, JF; Dömling, A; Huang, JW; Monfardini, I; Pellecchia, M | 1 |
| Che, P; Deng, J; Huang, J; Jiang, H; Li, H; Li, J; Lu, W; Shen, X; Zhang, Y; Zhu, J; Zou, S | 1 |
| Cardile, V; Crascì, L; Incerti, M; Panico, AM; Ronsisvalle, S; Vicini, P | 1 |
| Es Saadi, B; Labar, G; Lambert, DM; Marchand-Brynaert, J; Matuszak, N | 1 |
| Choi, H; Fiorilla, C; Gerwick, WH; Malloy, KL; Matainaho, T; Valeriote, FA | 1 |
| Donohoe, TJ; Kabeshov, MA; Rathi, AH; Smith, IE | 1 |
| Jang, BC; Kim, S; Kwon, TK; Lee, J; Park, JW | 1 |
| Devi, P; Ghate, M; Parikh, J; Vyas, VK | 1 |
| Bobade, VD; Mhaske, PC; Nandave, M; Narkhade, S; Shelke, SH; Walhekar, NM | 1 |
| Brodsky, JL; Dickey, CA; Gestwicki, JE; Jinwal, UK; Lee, HF; Li, X; Miyata, Y; Seguin, SP; Srinivasan, SR; Sun, D; Young, ZT | 1 |
| Geronikaki, AA; Liaras, KS; Pitta, EP | 1 |
| Gzella, AK; Kowiel, M; Lesyk, R; Suseł, A; Wojtyra, MN | 1 |
| Jiménez, C; Montaos, MA; Rodríguez, J; Segade, Y | 1 |
| Khawaja, S; Luo, M; Qiu, S; Rowse, M; Tsao, J; Wang, G; Xian, T; Yamauchi, Y; Yang, Z | 1 |
| Avoli, M; Hamidi, S | 1 |
| Fukuzumi, S; Inami, K; Kondo, S; Mochizuki, M; Nakanishi, I; Ohkubo, K; Ono, Y | 1 |
| Dingemanse, J; Guérard, N; Hoch, M; Zwingelstein, C | 1 |
| Bell, J; Cheng, SY; Eckerdt, F; Giles, FJ; Goldman, S; Iqbal, A; Lulla, RR; Nakano, I; Platanias, LC | 1 |
| Al-Dosari, MS; Al-Mishari, AA; Almoqbil, AN; Alsaid, MS; Ghorab, MM; Ragab, FA | 1 |
| Best, S; Cao, S; Charrier, C; Cheung, J; Cooper, IR; Craighead, M; Forward, H; Gault, Z; Hughes, D; Kirkham, J; Maclean, J; McCarroll, AJ; McGarry, D; Metzger, R; Moyo, E; Nelson, G; Pichowicz, M; Ratcliffe, AJ; Salisbury, AM; Savage, VJ; Stokes, NR; Walker, R; Warrilow, C | 1 |
| Fernando, D; Franklin, C; Garza, I; Gerding, JS; Lee, RE; Singh, A; Wallace, MJ; Yendapally, R | 1 |
| Fesatidou, M; Geronikaki, A; Liaras, K | 1 |
| Abdel Gawad, NM; Abdel-Aziz, MM; Abo-Ashour, MF; Abou-Seri, SM; Elaasser, MM; Eldehna, WM; George, RF | 1 |
| Berne, MEA; Campos, JC; Cunico, W; da Silva Nascente, P; da Silva, MAMP; de Oliveira Hübner, S; Gouvea, DP; Pereira, KM; Siqueira, GM; Zehetmeyr, FK | 1 |
| de Lima Ferreira, LP; de Melo Rêgo, MJB; de Moraes Gomes, PAT; de Siqueira, LRP; Leite, ACL | 1 |
| Blanco, MJ | 1 |
| Boopathy, S; Brown, RH; Danielson, EW; Fallini, C; Giampetruzzi, A; Gumina, V; Jeon, M; Landers, JE; Ratti, A | 1 |
| Tratrat, C | 1 |
| Carbone, D; Cascioferro, S; Cirrincione, G; Diana, P; Giovannetti, E; Parrino, B; Schillaci, D | 1 |
| Behbehani, H; Ibrahim, HM | 1 |
| Ciric, A; Geronikaki, A; Haroun, M; Ivanov, M; Petrou, A; Sokovic, M; Tratrat, C | 1 |
| Ahmed, N; Ali, S; Farooq, S; Hussain, M; Khan, MA; Khan, S; Shamim, S | 1 |
| Abd El Hadi, SR; Abdel-Aziz, HA; Abo-Ashour, MF; Abo-El Fetoh, ME; Abou-Seri, SM; Afify, H; Elgohary, MK | 1 |
33 review(s) available for thiazoles and thiazolidines
| Article | Year |
|---|---|
[Proline specific peptidases and their specific inhibitors].
Topics: Amino Acid Sequence; Aminopeptidases; Animals; Bacteria; Base Sequence; Cloning, Molecular; Endopeptidases; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Prolyl Oligopeptidases; Serine Endopeptidases; Substrate Specificity; Thiazoles; Thiazolidines | 1991 |
The roles of intracellular glutathione in antineoplastic chemotherapy.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Survival; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1986 |
Diet and exposure to N-nitroso compounds.
Topics: Bacteria; Diet; Food; Humans; Neoplasms; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1985 |
Nitrosatable precursors of mutagens in vegetables and soy sauce.
Topics: Animals; Benzylamines; Brassica; Chemical Phenomena; Chemistry; Glycine max; Indoles; Mutagenicity Tests; Mutagens; Neoplasms, Experimental; Nitrites; Thiazoles; Thiazolidines; Tyramine | 1985 |
Cytostatic and reverse-transforming therapies of cancer - a brief review and future prospects.
Topics: Animals; Antineoplastic Agents; Benzaldehydes; Cell Transformation, Neoplastic; Cyclic AMP; Growth Inhibitors; Humans; Interferons; Neoplasms; Protease Inhibitors; Solvents; Thiazoles; Thiazolidines; Vitamin A | 1982 |
Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine.
Topics: Aged; Animals; Antioxidants; Chemical Phenomena; Chemistry; Cysteine; Dogs; Drug Combinations; Folic Acid; Gastrointestinal Diseases; Humans; Liver Diseases; Longevity; Mice; Rats; Thiazoles; Thiazolidines | 1982 |
Enhancement of tissue glutathione for antioxidant and immune functions in malnutrition.
Topics: Animals; Antioxidants; Dietary Proteins; Glutathione; Immunity, Innate; Infections; Nutrition Disorders; Prodrugs; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Up-Regulation | 1994 |
Carbon disulphide. I. External and internal exposure to carbon disulphide of workers in the viscose industry.
Topics: Adult; Air Pollutants, Occupational; Carbon Disulfide; Cellulose; Creatinine; Environmental Monitoring; Humans; Male; Maximum Allowable Concentration; Middle Aged; Occupational Diseases; Occupational Exposure; Thiazoles; Thiazolidines | 1994 |
Endogenous formation of nitrosamines and oxidative DNA-damaging agents in tobacco users.
Topics: Areca; Carcinogens; DNA Damage; Flavonoids; Humans; Mouth; Nitrosamines; Nitrosation; Nitroso Compounds; Oral Hygiene; Phenols; Plants, Medicinal; Plants, Toxic; Polymers; Polyphenols; Reactive Oxygen Species; Smoking; Thiazoles; Thiazolidines; Tobacco, Smokeless | 1996 |
Glutathione: an overview of biosynthesis and modulation.
Topics: Animals; Buthionine Sulfoximine; Dipeptides; Enzyme Inhibitors; Esterification; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Kinetics; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Potential for selective modulation of glutathione in cancer chemotherapy.
Topics: Animals; Buthionine Sulfoximine; Cell Communication; Drug Resistance; Enzyme Inhibitors; Female; Gap Junctions; Glutamate-Cysteine Ligase; Glutathione; Humans; Mammary Neoplasms, Experimental; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1998 |
[Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese].
Topics: Alleles; Animals; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Genotype; Humans; Japan; Mixed Function Oxygenases; Mutation; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Substrate Specificity; Thiazoles; Thiazolidines | 1998 |
Drugs preventing Na+ and Ca2+ overload.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiazoles; Calcium; Calcium Channel Blockers; Guanidines; Heart; Homeostasis; Humans; Piperidines; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Hydrogen Exchangers; Sulfones; Thiazoles; Thiazolidines | 1999 |
Modulation of endogenous glutathione availability.
Topics: Acetylcysteine; Animals; Cysteine; Glutamine; Glutathione; Humans; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
[KRP-297, MCC-555].
Topics: Animals; Clinical Trials, Phase II as Topic; Diabetes Mellitus; Glucose; Humans; Hypoglycemic Agents; Lipid Metabolism; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2001 |
S 17092: a prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies.
Topics: Aging; Animals; Cognition Disorders; Humans; Indoles; Learning; Memory Disorders; Models, Animal; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substance P; Thiazoles; Thiazolidines | 2002 |
[Aminoguanidine and other AGE inhibitors].
Topics: Amides; Animals; Arteriosclerosis; Cardiovascular Diseases; Cataract; Clinical Trials as Topic; Diabetes Mellitus; Diabetic Nephropathies; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Glycation End Products, Advanced; Guanidines; Humans; Hydrazines; Hypoglycemic Agents; Thiadiazoles; Thiazoles; Thiazolidines | 2002 |
[OPB-9195].
Topics: Animals; Diabetic Angiopathies; Disease Models, Animal; Drug Design; Glycation End Products, Advanced; Guanidines; Humans; Hypoglycemic Agents; Thiadiazoles; Thiazoles; Thiazolidines | 2002 |
[Glutathione in therapy].
Topics: Animals; Cysteine; Diabetes Mellitus; Glutathione; Humans; Infections; Neurodegenerative Diseases; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2002 |
MK-767. Kyorin/Banyu/Merck.
Topics: Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Contraindications; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Thiazoles; Thiazolidines | 2003 |
[Design and synthesis of subtype- and species-selective peroxisome proliferator-activated receptor (PPAR) alpha ligands].
Topics: Animals; Drug Design; Humans; Phenylpropionates; PPAR alpha; Species Specificity; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2004 |
[Progress on the drug therapy for diabetic microangiopathies: AGE inhibitors].
Topics: Animals; Clinical Trials as Topic; Depression, Chemical; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Humans; Oxidative Stress; Pyridoxamine; Thiadiazoles; Thiamine; Thiazoles; Thiazolidines | 2005 |
[Development of therapeutic agents for diabetic neuropathies].
Topics: Aldehyde Reductase; Antioxidants; C-Peptide; Diabetic Neuropathies; Drug Design; Enzyme Inhibitors; Genetic Therapy; Glycation End Products, Advanced; Hedgehog Proteins; Humans; Indoles; Maleimides; Nerve Growth Factor; Oxidative Stress; Polymers; Protein Kinase C; Rhodanine; Thiadiazoles; Thiamine; Thiazoles; Thiazolidines; Trans-Activators; Vascular Endothelial Growth Factor A | 2005 |
Urinary tract infection in children.
Topics: Anti-Bacterial Agents; Child; Child, Preschool; Female; Humans; Infant; Male; Pyelonephritis; Pyrrolidonecarboxylic Acid; Secondary Prevention; Thiazoles; Thiazolidines; Urinary Tract Infections; Vesico-Ureteral Reflux | 2005 |
Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cytoskeletal Proteins; Endocytosis; Microscopy, Fluorescence; Models, Molecular; Mutation; Phosphorylation; Protein Kinase C; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2005 |
Chromosome dynamics: actin's gone fishing.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chromosome Segregation; Depsipeptides; Models, Biological; Nocodazole; Oocytes; Phalloidine; Spindle Apparatus; Starfish; Thiazoles; Thiazolidines | 2005 |
Antioxidants as novel agents for asthma.
Topics: Acetylcysteine; Anti-Asthmatic Agents; Antioxidants; Asthma; Cysteine; Glutathione; Humans; Oxidative Stress; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines | 2006 |
Dipeptidyl peptidase IV: a molecular switch of vascular actions of neuropeptide Y.
Topics: Atherosclerosis; Blood Vessels; Dipeptidyl Peptidase 4; Humans; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Neuropeptide Y; Pentanoic Acids; Serine Proteinase Inhibitors; Thiazoles; Thiazolidines; Vasoconstriction | 2006 |
Force fluctuation-induced relengthening of acetylcholine-contracted airway smooth muscle.
Topics: Acetylcholine; Actin Cytoskeleton; Animals; Asthma; Bridged Bicyclo Compounds, Heterocyclic; Depsipeptides; Humans; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; Myosins; Stress, Mechanical; Thiazoles; Thiazolidines | 2008 |
Thiazoles and thiazolidinones as antioxidants.
Topics: Animals; Antioxidants; Humans; Oxidative Stress; Thiazoles; Thiazolidines | 2013 |
Thiazoles and Thiazolidinones as COX/LOX Inhibitors.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Humans; Lipoxygenase Inhibitors; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2018 |
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues.
Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Disease Progression; Drug Delivery Systems; Drug Discovery; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Thiazoles; Thiazolidines; Thiosemicarbazones | 2019 |
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance.
Topics: Animals; Anti-Bacterial Agents; Benzene; Biofilms; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2020 |
45 trial(s) available for thiazoles and thiazolidines
| Article | Year |
|---|---|
Pidotimod in the prophylaxis of recurrent acute tonsillitis in childhood.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Pyrrolidonecarboxylic Acid; Recurrence; Thiazoles; Thiazolidines; Tonsillitis | 1992 |
[Clinical evaluation of letosteine activity in the treatment of acute febrile bronchitis in children. Double-blind controlled study versus placebo].
Topics: Acute Disease; Bronchitis; Bronchospirometry; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Expectorants; Female; Fever; Humans; Male; Thiazoles; Thiazolidines | 1989 |
[Drugs active on mucus in the primary treatment of chronic bronchitis. Controlled study of the activity of letosteine].
Topics: Bronchitis; Clinical Trials as Topic; Double-Blind Method; Expectorants; Humans; Mucus; Thiazoles; Thiazolidines | 1986 |
[The control of bronchial secretions in chronic hypersecretory bronchopneumopathies: the role of letosteine].
Topics: Adult; Aged; Bronchial Diseases; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Expectorants; Female; Humans; Male; Middle Aged; Mucus; Random Allocation; Thiazoles; Thiazolidines | 1986 |
Effects of a stable prostaglandin analogue, L-644,122, in healthy and hypertensive men.
Topics: Administration, Oral; Adult; Blood Pressure; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Parenteral; Male; Renal Circulation; Thiazoles; Thiazolidines; Vasodilator Agents | 1985 |
Thioproline toxicity.
Topics: Carcinoma, Squamous Cell; Central Nervous System; Humans; Kidney; Thiazoles; Thiazolidines | 1981 |
Reversal of cancer.
Topics: Antineoplastic Agents; Bucladesine; Cell Differentiation; Clinical Trials as Topic; Humans; Neoplasms; Thiazoles; Thiazolidines | 1983 |
[Letosteine in chronic obstructive bronchopneumopathy].
Topics: Adult; Aged; Bronchial Spasm; Bronchitis; Bronchopneumonia; Clinical Trials as Topic; Double-Blind Method; Expectorants; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pleurisy; Pulmonary Emphysema; Thiazoles; Thiazolidines | 1983 |
Thiazolidine-4-carboxylic acid, a selective drug against human cancers.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Lethal Dose 50; Male; Mice; Neoplasms; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1980 |
Preliminary clinical results with norgamem (thioproline) and revercan (2-amino-2-thiazoline): the first inducers of reverse transformation.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Clinical Trials as Topic; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasms; Thiazoles; Thiazolidines; Urinary Bladder Neoplasms | 1982 |
Lessons of the laetrile study.
Topics: Amygdalin; Attitude; Benzaldehydes; Clinical Trials as Topic; Complementary Therapies; Humans; Neoplasms; Philosophy; Politics; Quackery; Research Design; Thiazoles; Thiazolidines; United States | 1981 |
The efficacy and safety of moguisteine in comparison with codeine phosphate in patients with chronic cough.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antitussive Agents; Chronic Disease; Circadian Rhythm; Codeine; Cough; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Male; Middle Aged; Pulmonary Fibrosis; Safety; Thiazoles; Thiazolidines | 1995 |
[Telemestein and variations in blood concentrations of lipoprotein A].
Topics: Adult; Female; Humans; Hyperlipoproteinemias; Infant, Newborn; Lipoprotein(a); Male; Middle Aged; Nephelometry and Turbidimetry; Thiazoles; Thiazolidines; Time Factors | 1994 |
Pharmacokinetics and oral bioavailability of pidotimod in humans.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Immunologic Factors; Injections, Intramuscular; Male; Middle Aged; Protein Binding; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Pharmacokinetics of pidotimod in elderly volunteers and in renal failure patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Female; Half-Life; Humans; Immunologic Factors; Injections, Intravenous; Intestinal Absorption; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Renal Insufficiency; Thiazoles; Thiazolidines; Urea | 1994 |
Effect of food on the bioavailability of pidotimod in healthy volunteers.
Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Food-Drug Interactions; Humans; Immunologic Factors; Male; Pyrrolidonecarboxylic Acid; Spectrophotometry, Ultraviolet; Therapeutic Equivalency; Thiazoles; Thiazolidines | 1994 |
Ex vivo evaluation of pidotimod activity on cell-mediated immunity.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; CD3 Complex; Double-Blind Method; Female; Humans; Immunity, Cellular; Lymphocyte Count; Male; Middle Aged; Neoplasms; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Stimulation, Chemical; T-Lymphocytes; Thiazoles; Thiazolidines | 1994 |
Efficacy and safety of pidotimod in the treatment of recurrent respiratory infections in children.
Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Chemotaxis, Leukocyte; Child; Double-Blind Method; Female; Humans; Infant; Male; Phagocytosis; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Thiazoles; Thiazolidines | 1994 |
Pidotimod in the treatment of recurrent respiratory infections in paediatric patients.
Topics: Bronchitis; Child; Child, Preschool; Double-Blind Method; Female; Humans; Immunologic Factors; Laryngitis; Lymphocyte Count; Male; Otitis; Pharyngitis; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Rhinitis; Thiazoles; Thiazolidines; Tracheitis | 1994 |
Therapeutic efficacy and safety of pidotimod in the treatment of urinary tract infections in children.
Topics: Anti-Infective Agents, Urinary; Chemotaxis, Leukocyte; Child; Child, Preschool; Double-Blind Method; Female; Humans; Immunologic Factors; Male; Phagocytosis; Pyrrolidonecarboxylic Acid; Recurrence; Thiazoles; Thiazolidines; Urinary Tract Infections | 1994 |
Pidotimod in the treatment of patients affected by bacterial exacerbations of chronic bronchitis.
Topics: Adult; Aged; Bronchitis; Chronic Disease; Double-Blind Method; Female; Humans; Immunologic Factors; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Skin Tests; Sputum; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thiazoles; Thiazolidines | 1994 |
Evaluation of the efficacy of pidotimod in the exacerbations in patients affected with chronic bronchitis.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Bronchitis; Chronic Disease; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunologic Factors; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Respiratory Function Tests; Thiazoles; Thiazolidines | 1994 |
Ex vivo evaluation of pidotimod activity in patients with chronic obstructive pulmonary disease.
Topics: Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Follow-Up Studies; Granulocytes; Humans; Lung Diseases, Obstructive; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Role of immunoactivation with pidotimod in recurrent respiratory infections in childhood.
Topics: Adjuvants, Immunologic; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Risk Factors; Thiazoles; Thiazolidines; Tonsillitis | 1994 |
Pidotimod in the management of recurrent pharyngotonsillar infections in childhood.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Child; Double-Blind Method; Female; Humans; Male; Pharyngitis; Pyrrolidonecarboxylic Acid; Recurrence; Thiazoles; Thiazolidines; Tonsillitis | 1994 |
Pidotimod activity against chronic bronchitis exacerbations.
Topics: Adjuvants, Immunologic; Aged; Bronchitis; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Patient Dropouts; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Immunoactivity of pidotimod against episodes of recurrent tonsillitis in childhood.
Topics: Adjuvants, Immunologic; Adolescent; Anti-Bacterial Agents; Anti-Inflammatory Agents; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Pyrrolidonecarboxylic Acid; Recurrence; Thiazoles; Thiazolidines; Tonsillitis | 1994 |
Immunoactivation by pidotimod in children with recurrent respiratory infections.
Topics: Adjuvants, Immunologic; Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Humans; Interleukin-2; Leukocytes; Male; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Receptors, Interleukin-2; Recurrence; Respiratory Tract Infections; Thiazoles; Thiazolidines | 1994 |
A phase I/II trial of intravenous L-2-oxothiazolidine-4-carboxylic acid (procysteine) in asymptomatic HIV-infected subjects.
Topics: Adult; Aged; beta 2-Microglobulin; CD4-Positive T-Lymphocytes; Cysteine; Female; Glutathione; HIV Seropositivity; Humans; Infusions, Intravenous; Leukocyte Count; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Clinical trial of the efficacy and safety of moguisteine in patients with cough associated with chronic respiratory diseases.
Topics: Adult; Aged; Antitussive Agents; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Male; Middle Aged; Respiratory Tract Diseases; Thiazoles; Thiazolidines | 1993 |
[Pidotimod, a new biological response modifier, is able to partially prevent immune response changes related to surgical stress].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Anesthesia, General; Antibody Formation; Complement C3; Complement C4; Double-Blind Method; Female; Humans; Immune System; Immunologic Deficiency Syndromes; Interleukin-2; Lymphocyte Activation; Lymphocyte Subsets; Male; Middle Aged; Neutrophils; Phagocytosis; Pyrrolidonecarboxylic Acid; Respiratory Burst; Stress, Physiological; Surgical Procedures, Operative; Thiazoles; Thiazolidines | 1993 |
The effects of (L)-2-oxothiazolidine-4-carboxylate on urinary oxalate excretion.
Topics: Adult; Humans; Male; Oxalates; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group.
Topics: Acetylcysteine; Adult; Antioxidants; Bilirubin; Bronchoalveolar Lavage Fluid; Cardiac Output; Cysteine; Double-Blind Method; Free Radical Scavengers; Glutathione; Humans; Middle Aged; Prospective Studies; Pyrrolidonecarboxylic Acid; Respiration, Artificial; Respiratory Distress Syndrome; Thiazoles; Thiazolidines; Time Factors | 1997 |
L-2-Oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease.
Topics: Administration, Oral; Aged; Arteriosclerosis; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cholesterol; Coronary Disease; Cysteine; Double-Blind Method; Endothelium, Vascular; Female; Glutathione; Heart Rate; Humans; Hyperemia; Male; Middle Aged; Nitric Oxide; Nitroglycerin; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Triglycerides; Ultrasonography | 1998 |
A phase I/II evaluation of oral L-2-oxothiazolidine-4-carboxylic acid in asymptomatic patients infected with human immunodeficiency virus.
Topics: Adult; Anti-HIV Agents; Cysteine; Dose-Response Relationship, Drug; Double-Blind Method; Glutathione; HIV Infections; Humans; Leukocytes, Mononuclear; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Elevation of whole-blood glutathione in peritoneal dialysis patients by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug (Procysteine).
Topics: Administration, Oral; Cysteine; Double-Blind Method; Female; Glutathione; Humans; Kidney Failure, Chronic; Male; Middle Aged; Osmolar Concentration; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Pidotimod in the management of vulvar papillomatosis: double-blind clinical trial versus placebo.
Topics: Administration, Oral; Adolescent; Adult; Biopsy; Colposcopy; Condylomata Acuminata; Double-Blind Method; Female; Humans; Immunologic Factors; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Treatment Outcome; Vulvar Diseases | 1998 |
The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis.
Topics: Administration, Oral; Adult; Amyotrophic Lateral Sclerosis; Glutathione; Humans; Infusions, Intravenous; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
Prophylaxis with the novel immunomodulator pidotimod reduces the frequency and severity of upper respiratory tract infections in children with Down's syndrome.
Topics: Adolescent; Child; Child, Preschool; Down Syndrome; Female; Humans; Immunologic Factors; Incidence; Male; Pyrrolidonecarboxylic Acid; Recurrence; Respiratory Tract Infections; Severity of Illness Index; Thiazoles; Thiazolidines | 1999 |
Pharmacodynamic and pharmacokinetic profile of S 17092, a new orally active prolyl endopeptidase inhibitor, in elderly healthy volunteers. A phase I study.
Topics: Administration, Oral; Aged; Double-Blind Method; Electroencephalography; Female; Humans; Indoles; Male; Middle Aged; Prolyl Oligopeptidases; Protease Inhibitors; Psychometrics; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles; Thiazolidines | 2000 |
(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1.
Topics: Calcium Oxalate; Calcium, Dietary; Cysteine; Female; Humans; Hyperoxaluria, Primary; Infusions, Intravenous; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Treatment Outcome | 2001 |
Clinical evaluation and changes of the respiratory epithelium function after administration of Pidotimod in Greek children with recurrent respiratory tract infections.
Topics: Adjuvants, Immunologic; Child; Child, Preschool; Female; Greece; Humans; Male; Mucociliary Clearance; Prospective Studies; Pyrrolidonecarboxylic Acid; Respiratory Mucosa; Respiratory Tract Infections; Thiazoles; Thiazolidines; Treatment Outcome | 2002 |
Analysis of the therapeutic effect of sodium copper chlorophyllin tablet in treating 60 cases of leukopenia.
Topics: Adolescent; Adult; Ascorbic Acid; Chlorophyllides; Female; Humans; Leukocyte Count; Leukopenia; Male; Middle Aged; Tablets; Thiazoles; Thiazolidines; Treatment Outcome | 2005 |
A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colorado; Dermatitis, Atopic; Dermatologic Agents; Double-Blind Method; Drug Combinations; Female; Glycyrrhetinic Acid; Humans; Hyaluronic Acid; Male; Middle Aged; Plant Extracts; Severity of Illness Index; Texas; Thiazoles; Thiazolidines; Treatment Outcome; Vitis | 2006 |
Effect of Hepatic or Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Ponesimod, a Selective S1P1 Receptor Modulator.
Topics: Adult; Area Under Curve; Case-Control Studies; Female; Humans; Liver Diseases; Male; Middle Aged; Receptors, Lysosphingolipid; Renal Insufficiency; Severity of Illness Index; Thiazoles; Thiazolidines | 2016 |
1170 other study(ies) available for thiazoles and thiazolidines
| Article | Year |
|---|---|
Inhibition of multiplication of Mycobacterium leprae by several antithyroid drugs.
Topics: Aniline Compounds; Animals; Antithyroid Agents; Drug Evaluation; Drug Resistance, Microbial; Leprostatic Agents; Leprosy; Methimazole; Mice; Mycobacterium leprae; Phenyl Ethers; Propylthiouracil; Thiazoles; Thiazolidines; Thiones; Thiourea; Thyroid (USP) | 1975 |
Effects of MK-771 on the isolated amphibian spinal cord: comparison with thyrotropin-releasing hormone.
Topics: Animals; Bufonidae; Dipeptides; In Vitro Techniques; Membrane Potentials; Spinal Cord; Thiazoles; Thiazolidines; Thyrotropin-Releasing Hormone | 1979 |
A novel orally active converting-enzyme inhibitor YS 980: effects on blood pressure in spontaneously hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Aldosterone; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Enkephalin, Leucine; Enkephalins; Hypertension; Kallikreins; Kinins; Male; Rats; Renin; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1979 |
Inhibition of dimethyltryptamine biosynthesis by N,N'-bis-(3-methyl-2-thiazolidinylidene)succinamide (I) and 2-imino-3-methylthiazolidine (II).
Topics: Adrenal Glands; Animals; Cattle; Dialysis; Humans; In Vitro Techniques; Kinetics; Liver; Lung; Methyltransferases; N,N-Dimethyltryptamine; Phenylethanolamine N-Methyltransferase; Rabbits; Thiazoles; Thiazolidines; Time Factors; Tryptamines | 1978 |
Potentiating mechanism of bradykinin action on smooth muscle by sulfhydryl compounds.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Animals; Bradykinin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors | 1979 |
Restoration of "contact inhibition" in tumour cells in tissue culture by treatment with thiazolidine-4-carboxylic acid [proceedings].
Topics: Contact Inhibition; HeLa Cells; Humans; Thiazoles; Thiazolidines | 1979 |
[Value of tiadilon in hepatobiliary pathology].
Topics: Adult; Aged; Alcoholic Intoxication; Arginine; Asthenia; Dietary Fats; Female; Hepatitis, Viral, Human; Humans; Liver Diseases; Male; Middle Aged; Thiazoles; Thiazolidines | 1979 |
[A new contribution to the treatment of chronic bronchopneumopathies: letosteine].
Topics: Adult; Aged; Amino Acids; Bronchial Diseases; Chronic Disease; Expectorants; Female; Humans; Lung Diseases; Male; Middle Aged; Thiazoles; Thiazolidines | 1979 |
Regression of "hormone-independent" DMBA-induced mammary carcinomas in response to GP 48989 and its effects on hormone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Benz(a)Anthracenes; Carcinoma; Castration; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Thiazoles; Thiazolidines | 1976 |
The isolation and identification of 2-methyl-2,4-thiazolidine dicarboxylate as a by-product in the conversion of cysteine to glucose in the perfused rat liver.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Dicarboxylic Acids; Dietary Proteins; Gluconeogenesis; Kidney; Lactates; Liver; Male; Pyruvates; Rats; Thiazoles; Thiazolidines | 1977 |
Increased rate of survival in Streptococcus pneumoniae-infected rats treated with the new immunomodulator Pidotimod.
Topics: Adjuvants, Immunologic; Animals; Male; Pneumonia, Pneumococcal; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1992 |
Pidotimod stimulates natural killer cell activity and inhibits thymocyte cell death.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Calcium; Cellular Senescence; Cytotoxicity, Immunologic; Killer Cells, Natural; Mice; Mice, Inbred C3H; Pyrrolidonecarboxylic Acid; Spleen; T-Lymphocytes; Thiazoles; Thiazolidines | 1992 |
Roles of glutathione and glutathione peroxidase in the protection against endothelial cell injury induced by 15-hydroperoxyeicosatetraenoic acid.
Topics: Animals; Antioxidants; Azoles; Buthionine Sulfoximine; Carotid Arteries; Cattle; Cells, Cultured; Endothelium, Vascular; Glutathione; Glutathione Peroxidase; Isoindoles; Kinetics; Leukotrienes; Lipid Peroxides; Maleates; Methionine Sulfoximine; Organoselenium Compounds; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Selenium; Sodium Selenite; Thiazoles; Thiazolidines | 1992 |
3-[4-[1-(6-Fluorobenzo[b]thiophen-3-yl)-4-piperazinyl]butyl]- 2,5,5-trimethyl-4-thiazolidinone: a new atypical antipsychotic agent for the treatment of schizophrenia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Mice; Rats; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Substrate Specificity; Tetrahydronaphthalenes; Thiazoles; Thiazolidines | 1992 |
Inhibition of mutagenesis by p-aminobenzoic acid as a nitrite scavenger.
Topics: 4-Aminobenzoic Acid; Food Analysis; Glutathione; Mutagenesis; Mutagenicity Tests; Nitrites; Salmonella typhimurium; Thiazoles; Thiazolidines | 1992 |
Sites of action of 2-thiazoline-2-thiol on biogenesis of thyroid hormones.
Topics: Animals; Antithyroid Agents; Iodine; Male; Peroxidases; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines; Thyroid Hormones; Thyroxine; Triiodothyronine | 1992 |
Immunopharmacology of Pidotimod: effect on natural killer cell activity and thymocyte cell death.
Topics: Animals; Apoptosis; Cell Death; Dexamethasone; Killer Cells, Natural; Mice; Mice, Inbred C3H; Pyrrolidonecarboxylic Acid; T-Lymphocytes; Thiazoles; Thiazolidines | 1992 |
Evaluation of the kinetics of the immunomodulating activity of Pidotimod on human neutrophils.
Topics: Adjuvants, Immunologic; Adult; Humans; Neutrophils; Phagocytosis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Ex vivo evaluation of Pidotimod effect on immune response.
Topics: Adjuvants, Immunologic; Adult; Chemotaxis, Leukocyte; Humans; Immunity, Cellular; Lymphocyte Activation; Male; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Activity of the new immunostimulant PGT/1A against experimental bacterial infections.
Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Male; Mice; Mice, Inbred ICR; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Effect of Pidotimod, a new immunostimulating agent, on some aspects of immune response. In vitro study.
Topics: Adjuvants, Immunologic; Complement System Proteins; Humans; Immunity, Cellular; Lymphocyte Activation; Lymphocytes; Neutrophils; Phagocytosis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Assessment of exposure to carbon disulfide in viscose production workers from urinary 2-thiothiazolidine-4-carboxylic acid determinations.
Topics: Adult; Air Pollutants, Occupational; Carbon Disulfide; Environmental Monitoring; Follow-Up Studies; Humans; Male; Occupational Exposure; Respiratory Protective Devices; Sensitivity and Specificity; Textile Industry; Thiazoles; Thiazolidines | 1992 |
Studies on endogenous formation of N-nitroso compounds in the guinea pig supplemented with proline or thioproline and sodium nitrate.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Gastric Acidity Determination; Guinea Pigs; Hydrogen-Ion Concentration; Male; Nitrates; Nitrosamines; Nitrosation; Nitroso Compounds; Proline; Thiazoles; Thiazolidines | 1992 |
Enalapril hepatotoxicity in the rat. Effects of modulators of cytochrome P450 and glutathione.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enalapril; Enzyme Induction; Glutathione; Inactivation, Metabolic; Liver; Liver Diseases; Male; Necrosis; Pregnenolone Carbonitrile; Protoporphyrins; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1992 |
Influence of fruit and vegetable juices on the endogenous formation of N-nitrosoproline and N-nitrosothiazolidine-4-carboxylic acid in humans on controlled diets.
Topics: Adult; Beverages; Diet; Fruit; Humans; Male; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines; Vegetables | 1992 |
Elevation of lung glutathione by oral supplementation of L-2-oxothiazolidine-4-carboxylate protects against oxygen toxicity in protein-energy malnourished rats.
Topics: Administration, Oral; Animals; Body Weight; Glutathione; Lung; Magnetic Resonance Spectroscopy; Organ Size; Oxygen; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1992 |
Oxidation of L-thiazolidine-4-carboxylate by L-proline dehydrogenase in Escherichia coli.
Topics: Antioxidants; Cell Membrane; Escherichia coli; Kinetics; Oxidation-Reduction; Oxygen; Proline; Proline Oxidase; Spectrum Analysis; Thiazoles; Thiazolidines | 1992 |
Failure of glutathione and cysteine prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Animals; Chlorpropamide; Cysteine; Ethanol; Glutathione; Male; Prodrugs; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1992 |
Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes.
Topics: Animals; Cells, Cultured; Chelating Agents; Cysteine; Glutathione; Indicators and Reagents; Liver; Male; Methionine; Phenanthrolines; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfates; Taurine; Thiazoles; Thiazolidines | 1992 |
Burn-induced gastric mucosal hemodynamic disturbance in the rat. Role of platelet-activating factor.
Topics: Animals; Azepines; Blood Pressure; Burns; Gastric Mucosa; Hemodynamics; Hemoglobins; Male; Oxygen; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Regional Blood Flow; Thiazoles; Thiazolidines; Triazoles | 1992 |
Protection against acetaminophen hepatotoxicity by ribose-cysteine (RibCys).
Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Mice; Prodrugs; Thiazoles; Thiazolidines | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines | 1992 |
Stabilization of actin filaments at early times after adenovirus infection and in heat-shocked cells.
Topics: Actins; Adenoviridae Infections; Adenoviruses, Human; Bridged Bicyclo Compounds, Heterocyclic; Deoxyribonuclease I; Drug Resistance, Microbial; Fluorescent Antibody Technique; Heat-Shock Proteins; HeLa Cells; Humans; Thiazoles; Thiazolidines | 1991 |
Functional analysis of the CPS I upstream sequences with a cat assay.
Topics: Antineoplastic Agents; Carbamoyl-Phosphate Synthase (Ammonia); Carcinoma, Hepatocellular; Gene Expression; Humans; Liver Neoplasms; Plasmids; Regulatory Sequences, Nucleic Acid; Thiazoles; Thiazolidines; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1991 |
Pharmacological properties of YM461, a new orally active platelet-activating factor antagonist.
Topics: Administration, Oral; Animals; Azepines; Blood Platelets; Blood Pressure; Cell Membrane; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles | 1991 |
[Effect of thioproline in vitro on selected functions of peripheral blood lymphocytes from healthy persons and patients with lympho- proliferative syndromes].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; B-Lymphocytes; Blood Donors; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; DNA; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Models, Biological; T-Lymphocytes; Thiazoles; Thiazolidines | 1991 |
The effect of Heparegen and D-penicillamine on the activity of some ammonia metabolizing enzymes in liver and brain of rats intoxicated with ethanol.
Topics: Alcoholic Intoxication; Ammonia; Animals; Antioxidants; Brain; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutaminase; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Penicillamine; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
Glutathione and glutathione conjugate efflux from cultured liver cells.
Topics: Animals; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Ethacrynic Acid; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Isoxazoles; Liver; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1991 |
Thiazolidine-4-carboxylate and 2-phenylthiazolidine-4-carboxylate are active as cysteine precursors but have no effect on growth of a methionine-dependent tumor in rats.
Topics: Amino Acids; Animals; Antineoplastic Agents; Body Weight; Cysteine; Glutathione; Male; Methionine; Rats; Rats, Inbred Strains; Rhabdomyosarcoma; Thiazoles; Thiazolidines | 1992 |
Selective modulation of glutathione in mouse brain regions and its effect on acrylamide-induced neurotoxicity.
Topics: Acrylamides; Animals; Brain; Buthionine Sulfoximine; Drug Interactions; Female; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Injections, Spinal; Liver; Maleates; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the L-cysteine prodrug, RibCys.
Topics: Animals; Cysteine; Glutathione; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Prodrugs; Thiazoles; Thiazolidines | 1991 |
Quantitative relationship between oral nitrate-reducing activity and the endogenous formation of N-nitrosoamino acids in humans.
Topics: Administration, Oral; Adult; Chlorhexidine; Chromatography, Gas; Humans; Male; Middle Aged; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Saliva; Thiazoles; Thiazolidines | 1991 |
Detection of a new intermediate product of indolealkylamine metabolism in the brain.
Topics: Animals; Brain Chemistry; Cattle; Cysteine; Indoles; Rats; Swine; Thiazoles; Thiazolidines | 1991 |
High-performance liquid chromatographic method for the determination of RGH-5702 in plasma samples.
Topics: Animals; Cell Survival; Chromatography, High Pressure Liquid; Dogs; Reproducibility of Results; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 1991 |
Anti-inflammatory effects of LY221068 and LY269415.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Calcimycin; Guinea Pigs; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoxygenase Inhibitors; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC).
Topics: Administration, Oral; Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrin Fibrinogen Degradation Products; Fibrinogen; Gabexate; Infusions, Intravenous; Injections, Intraperitoneal; Partial Thromboplastin Time; Platelet Activating Factor; Platelet Count; Prothrombin Time; Rats; Thiazoles; Thiazolidines | 1991 |
[The blocking effect of topically subepithelial injection of thioproline and vitamin A acid in experimental oral premalignant].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cheek; Cricetinae; Epithelium; Injections; Mesocricetus; Mouth Neoplasms; Precancerous Conditions; Thiazoles; Thiazolidines; Tretinoin | 1991 |
Pharmacokinetic study of 14C-letosteine in man after oral intake and steady-state.
Topics: Administration, Oral; Adult; Biotransformation; Expectorants; Half-Life; Humans; Intestinal Absorption; Male; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 1991 |
Modulation of the immune response to tumors by a novel synthetic compound, (4R)-3-benzoyl-N-[(1R)-1-phenylethyl]-4-thiazolidinecarboxamide (RS-0481).
Topics: Adjuvants, Immunologic; Animals; Bone Marrow; Colony-Stimulating Factors; Female; Hypersensitivity, Delayed; Interleukin-2; Killer Cells, Natural; Macrophage Activation; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasms, Experimental; T-Lymphocytes; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Thiazoles; Thiazolidines | 1991 |
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Eflornithine; Ellagic Acid; Isothiocyanates; Male; Precancerous Conditions; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfides; Thiazoles; Thiazolidines; Thiocyanates | 1991 |
Studies on heterocyclic compounds: 1,3-thiazolidin-4-one derivatives. V. Pharmacological activity of substituted 2-phenyl-3-(N,N-dimethylaminoprophyl)-1,3-thiazolidin-4-one .
Topics: Animals; Female; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Schiff Bases; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1991 |
L-cysteine prodrug protects against cyclophosphamide urotoxicity without compromising therapeutic activity.
Topics: Animals; Cyclophosphamide; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Glutathione; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Prodrugs; Thiazoles; Thiazolidines; Time Factors; Urinary Bladder | 1991 |
Nitrite-trapping capacity of thioproline in the human body.
Topics: Ascorbic Acid; Humans; Nitrites; Nitroso Compounds; Thiazoles; Thiazolidines; Thiocyanates | 1991 |
Bacterial formation of N-nitroso compounds in the rat stomach after omeprazole-induced achlorhydria.
Topics: Achlorhydria; Animals; Bacteria; Gastric Mucosa; Male; Nitrosamines; Nitroso Compounds; Omeprazole; Rats; Rats, Inbred Strains; Stomach; Thiazoles; Thiazolidines | 1991 |
Epidemiological study of precursor lesions of oesophageal cancer among young persons in Huixian, China.
Topics: Adolescent; Adult; Case-Control Studies; China; Chronic Disease; Esophageal Neoplasms; Esophagitis; Female; Humans; Male; Nitroso Compounds; Precancerous Conditions; Risk Factors; Thiazoles; Thiazolidines | 1991 |
Volatile N-nitrosamines in fish meal, with special reference to the mechanism of formation of N-nitrosothiazolidine.
Topics: Carcinogens; Cysteamine; Fish Products; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines; Volatilization | 1991 |
Recent studies in Canada on the occurrence and formation of N-nitroso compounds in foods and food contact materials.
Topics: Canada; Food Analysis; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1991 |
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine | 1991 |
LY178002 reduces rat brain damage after transient global forebrain ischemia.
Topics: Animals; Brain; Brain Ischemia; Corpus Striatum; Ferritins; Hippocampus; Iron; Male; Methemoglobin; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Thiobarbiturates | 1991 |
Uptake and metabolism of L-2-oxo-[35S]thiazolidine-4-carboxylate by rat cells is slower than that of L-[35S]cysteine or L-[35S]methionine.
Topics: Animals; Biological Transport; Chromatography, High Pressure Liquid; Cysteine; Glutathione; In Vitro Techniques; Intestine, Small; Kidney Tubules; Liver; Male; Methionine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Thiazoles; Thiazolidines | 1991 |
Bacterial formation of N-nitroso compounds from administered precursors in the rat stomach after omeprazole-induced achlorhydria.
Topics: Achlorhydria; Animals; Escherichia coli; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Morpholines; Nitrosamines; Nitroso Compounds; Omeprazole; Pseudomonas aeruginosa; Rats; Rats, Inbred Strains; Stomach; Thiazoles; Thiazolidines | 1991 |
Determination of tetrahydrophtalimide and 2-thiothiazolidine-4-carboxylic acid, urinary metabolites of the fungicide captan, in rats and humans.
Topics: Agriculture; Animals; Captan; Chromatography, Gas; Environmental Monitoring; Humans; Male; Occupational Exposure; Phthalimides; Rats; Rats, Inbred Strains; Sulfur; Thiazoles; Thiazolidines | 1991 |
A novel reagent, dialkylphosphite, for peptide synthesis.
Topics: Amino Acid Sequence; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Phosphorous Acids; Spectrometry, Mass, Fast Atom Bombardment; Thiazoles; Thiazolidines | 1991 |
Effect of buthionine sulfoximine on toxicity of verapamil and doxorubicin to multidrug resistant cells and to mice.
Topics: Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Flupenthixol; Glutathione; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Verapamil | 1991 |
Changes in glutathione concentration in hypothermically perfused dog kidneys.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cold Temperature; Dithionitrobenzoic Acid; Dogs; Glutathione; Glutathione Disulfide; Kidney; Methionine Sulfoximine; Organ Preservation; Osmolar Concentration; Perfusion; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors; Tissue Distribution | 1991 |
Protective effect of prostaglandin A2 against menadione-induced cell injury in cultured porcine aorta endothelial cells.
Topics: Animals; Aorta; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Methionine; Prostaglandins A; Pyrrolidonecarboxylic Acid; Swine; Thiazoles; Thiazolidines; Time Factors; Vitamin K | 1991 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human.
Topics: Adult; Cysteine; Glutathione; Humans; Lymphocytes; Male; Middle Aged; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1991 |
Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Glomerulonephritis, Membranous; Hypercholesterolemia; Male; Metabolic Clearance Rate; Methylprednisolone; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Ticlopidine; Triazoles | 1991 |
Simple high-performance liquid chromatographic method for the determination of PGT/1A, a new immunostimulating drug, in biological fluids.
Topics: Acetonitriles; Adjuvants, Immunologic; Adult; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Male; Phosphates; Potassium; Potassium Compounds; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1991 |
[Synthesis of gallic acid derivatives with L-thiazolidin-4-carboxylic acid and study on their antiradical and antitoxic activity].
Topics: Acetaldehyde; Animals; Antidotes; Doxorubicin; Formaldehyde; Free Radical Scavengers; Gallic Acid; Male; Mice; Mice, Inbred Strains; Thiazoles; Thiazolidines | 1990 |
Liquid chromatographic determination of 2-thioxothiazolidine-4-carboxylic acid isolated from urine by affinity chromatography on organomercurial agarose gel.
Topics: Chromatography, Affinity; Creatinine; Humans; Organomercury Compounds; Sepharose; Thiazoles; Thiazolidines | 1990 |
Effects of an aldose reductase inhibitor, ONO-2235, insulin and their combination on the altered responsiveness to the nerve stimulation and agonists of the isolated atria of diabetic rats.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Electric Stimulation; Heart Atria; In Vitro Techniques; Insulin; Male; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Rhodanine; Sugar Alcohol Dehydrogenases; Synaptic Transmission; Thiazoles; Thiazolidines | 1990 |
Marked nitrosation by stimulation with lipopolysaccharide in ascorbic acid-deficient rats.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Body Weight; Bone Diseases, Metabolic; Escherichia coli; Female; Kidney; Lipopolysaccharides; Liver; Nitrates; Nitroso Compounds; Rats; Rats, Mutant Strains; Spleen; Thiazoles; Thiazolidines | 1990 |
Accumulation of carbon disulphide metabolites.
Topics: Air Pollutants, Occupational; Azides; Carbon Disulfide; Creatinine; Environmental Monitoring; Humans; Male; Predictive Value of Tests; Thiazoles; Thiazolidines | 1990 |
Impairment of mitochondrial membrane by ethanol and protective effect of a thiazolidine compound in in vitro and in vivo experiments.
Topics: Animals; Arginine; Cell Membrane; Ethanol; Fatty Acids; Glutathione; Membrane Lipids; Microsomes, Liver; Rats; Thiazoles; Thiazolidines | 1990 |
Effects of L-2-oxothiazolidine-4-carboxylate, a cysteine pro-drug, on teratogenicity of 5-fluorouracil in mice.
Topics: Animals; Body Weight; Cystine; Drug Synergism; Female; Fluorouracil; Glutathione; Limb Deformities, Congenital; Liver; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1990 |
Biological monitoring of carbon disulfide.
Topics: Air Pollutants, Occupational; Antipyrine; Carbon Disulfide; Creatinine; Environmental Monitoring; Humans; Thiazoles; Thiazolidines | 1990 |
L-2-oxothiazolidine-4-carboxylate as a cysteine precursor: efficacy for growth and hepatic glutathione synthesis in chicks and rats.
Topics: Administration, Oral; Animals; Chickens; Cysteine; Diet; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Random Allocation; Rats; Rats, Inbred Strains; Regression Analysis; Thiazoles; Thiazolidines; Weight Gain | 1990 |
Are free radicals and not quinones the haptenic species derived from urushiols and other contact allergenic mono- and dihydric alkylbenzenes? The significance of NADH, glutathione, and redox cycling in the skin.
Topics: Animals; Benzene; Benzene Derivatives; Catechols; Dermatitis, Contact; Free Radicals; Glutathione; Haptens; Male; Mice; NAD; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Quinones; Skin; Thiazoles; Thiazolidines | 1990 |
Detoxifying potential of thioproline against N-nitroso compounds, N-nitrosodimethylamine and N-nitrosocimetidine.
Topics: Animals; Cimetidine; Cytochrome P-450 CYP2E1; Dimethylnitrosamine; Formaldehyde; In Vitro Techniques; Inactivation, Metabolic; Male; Microsomes, Liver; Nitroso Compounds; Oxidoreductases, N-Demethylating; Rats; Rats, Inbred F344; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1990 |
Activity of PGT/1A, a new immunostimulating drug, on macrophages and lymphocytes in immunodepressed mice.
Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Immunosuppression Therapy; Lymphocytes; Macrophages; Mice; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1990 |
The interaction between ethanol and cysteine on the central depressant effects of ethanol in mice.
Topics: Animals; Cysteine; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Injections, Intraventricular; Isethionic Acid; Male; Mice; Posture; Pyrrolidonecarboxylic Acid; Reflex; Thiazoles; Thiazolidines | 1990 |
Tissue contents and urinary excretion of taurine after administration of L-cysteine and L-2-oxothiazolidine-4-carboxylate to rats.
Topics: Animals; Caseins; Cysteine; Cysteine Dioxygenase; Cystine; Dietary Proteins; Dioxygenases; Injections, Intraperitoneal; Liver; Male; Oxygenases; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines; Tissue Distribution | 1990 |
Biological effect of orally active platelet-activating factor receptor antagonist SM-10661.
Topics: Administration, Oral; Animals; Blood Pressure; Bronchi; Guinea Pigs; Humans; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1990 |
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin | 1986 |
Formation of thiazolidine-4-carboxylic acid represents a main metabolic pathway of 5-hydroxytryptamine in rat brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Female; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Rats; Rats, Inbred Strains; Serotonin; Thiazoles; Thiazolidines; Time Factors; Tryptamines | 1989 |
Determination of 2-carboxy thiazolidine-4-carboxylic acid in biological fluids by ion-exchange chromatography.
Topics: Animals; Body Fluids; Chromatography, Ion Exchange; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
[Metabolism of L-thiazolidine-4-carboxylic acid].
Topics: Animals; Formaldehyde; Inactivation, Metabolic; Kidney; Male; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Oxidation-Reduction; Parenteral Nutrition, Total; Proline Oxidase; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
The anti-inflammatory effects of LY178002 and LY256548.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Arthritis; Arthritis, Experimental; Cyclooxygenase Inhibitors; Freund's Adjuvant; Guinea Pigs; In Vitro Techniques; Neutrophils; Thiazoles; Thiazolidines | 1989 |
[The blocking effect of topically subepithelial injected thioproline on experimental oral premalignant lesions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cheek; Cricetinae; Female; Male; Mesocricetus; Mouth Neoplasms; Precancerous Conditions; Thiazoles; Thiazolidines | 1989 |
[Treated experimental premalignant oral lesion transplants in nude mice].
Topics: Animals; Antineoplastic Agents; Cricetinae; Drugs, Chinese Herbal; Female; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Mucosa; Mouth Neoplasms; Neoplasm Transplantation; Precancerous Conditions; Thiazoles; Thiazolidines; Tretinoin | 1989 |
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione; Methionine Sulfoximine; Nitroimidazoles; Oxygen; Pyrrolidonecarboxylic Acid; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines | 1989 |
Effect of prostaglandin E1 analogue TFC 612 on diabetic neuropathy in streptozocin-induced diabetic rats. Comparison with aldose reductase inhibitor ONO 2235.
Topics: Adenosine Triphosphate; Aldehyde Reductase; Alprostadil; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Electrophysiology; Inositol; Lactates; Male; Myelin Sheath; Nerve Fibers; Phosphocreatine; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Streptozocin; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1989 |
Cytostatic influence of thioproline on peripheral lymphocytes of healthy persons and non-Hodgkin's lymphoma patients.
Topics: Adolescent; Adult; Antineoplastic Agents; Cyclic AMP; Cyclic GMP; Humans; In Vitro Techniques; Lymphocytes; Lymphoma, Non-Hodgkin; Reference Values; Thiazoles; Thiazolidines; Thymidine | 1989 |
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Alteration of precocene II-induced hepatotoxicity by modulation of hepatic glutathione levels.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzopyrans; Buthionine Sulfoximine; Glutathione; Insecticides; Liver; Male; Methionine Sulfoximine; Plants; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Reference Values; Thiazoles; Thiazolidines | 1989 |
Modulation of endoperoxide product levels and cyclophosphamide-induced injury by glutathione repletion.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Glutathione; Lung; Lung Injury; Male; Prostaglandin Endoperoxides; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines | 1989 |
[Preparation of cerebral ischemia-induced amnesic model in mice and ameliorative effect of several compounds on the model].
Topics: Amnesia; Animals; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred ICR; Pyrrolidinones; Thiazoles; Thiazolidines | 1989 |
Reversed-phase ion-pair high-performance liquid chromatographic determination of 2-carboxythiazolidine-4-carboxylic acid in plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Humans; Male; Rats; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 1989 |
YM461, a PAF antagonist, blocks antigen-induced late airway responses and airway hyperresponsiveness in allergic sheep.
Topics: Aerosols; Animals; Antigens; Ascaris; Carbachol; Dose-Response Relationship, Drug; Platelet Activating Factor; Pyridines; Respiratory Hypersensitivity; Sheep; Thiazoles; Thiazolidines | 1989 |
Influence of a cysteine prodrug, L-2-oxothiazolidine-4-carboxylic acid, on the urinary elimination of mercapturic acids of ethylene oxide, dibromoethane, and acrylonitrile: a dose-effect study.
Topics: Acetylcysteine; Acrylonitrile; Animals; Ethylene Dibromide; Ethylene Oxide; Glutathione; Hydrocarbons, Brominated; Kidney; Liver; Male; Nitriles; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Time Factors | 1989 |
Determination of urinary 2-thiothiazolidine-4-carboxylic acid by automated high performance liquid chromatography, as an index of carbon disulfide exposure.
Topics: Carbon Disulfide; Chromatography, High Pressure Liquid; Environmental Exposure; Environmental Monitoring; Humans; Thiazoles; Thiazolidines | 1989 |
Role of glutathione status in protection against ethanol-induced gastric lesions.
Topics: Acetylcysteine; Animals; Cysteamine; Ethanol; Gastric Mucosa; Glutathione; Male; Maleates; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Stomach Ulcer; Thiazoles; Thiazolidines | 1989 |
Synthesis of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine and analysis of oils implicated in the Spanish toxic oil syndrome for its presence.
Topics: Brassica; Chromatography, Ion Exchange; Fatty Acids, Monounsaturated; Gas Chromatography-Mass Spectrometry; Plant Oils; Rapeseed Oil; Syndrome; Thiazoles; Thiazolidines | 1989 |
Structural identification of a heterocyclic compound implicated in the Spanish toxic oil syndrome.
Topics: Brassica; Crystallography; Fatty Acids, Monounsaturated; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Oils; Rapeseed Oil; Spectrum Analysis; Syndrome; Thiazoles; Thiazolidines | 1989 |
Spanish toxic oil syndrome: an isothiocyanate-derived compound cannot be substantiated as a causative agent.
Topics: Brassica; Ethylenethiourea; Fatty Acids, Monounsaturated; Imidazoles; Imidazolidines; Plant Oils; Rapeseed Oil; Syndrome; Thiazoles; Thiazolidines | 1989 |
Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cricetinae; Cytochalasin D; Cytochalasins; Cytoskeleton; Mice; Microscopy, Fluorescence; Thiazoles; Thiazolidines; Time Factors | 1989 |
Protective role of intracellular glutathione against oxidized low density lipoprotein in cultured endothelial cells.
Topics: Animals; Antimetabolites; Aorta, Thoracic; Buthionine Sulfoximine; Cattle; Cell Survival; Cells, Cultured; Endothelium, Vascular; Fetus; Glutathione; Kinetics; Lipoproteins, LDL; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1989 |
Short-term primary culture of rat prostate tumor epithelial cells on reconstituted basement membrane as a useful in vitro model to assess drug action on prostatic cancer: efficacy of the thiazolidinedione derivative CGP 19984.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Basement Membrane; Disease Models, Animal; Epithelium; Male; Prostatic Neoplasms; Rats; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1989 |
[Malignant transformation of NIH 3T3 cells by urine NTCA in normal population of Lin-xian County].
Topics: Animals; Cell Transformation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Nitroso Compounds; Rats; Thiazoles; Thiazolidines | 1989 |
Crystal structure of L-2-oxothiazolidine-4-carboxylic acid.
Topics: Crystallization; Hydrogen Bonding; Models, Molecular; Pyrrolidonecarboxylic Acid; Software; Thiazoles; Thiazolidines; X-Ray Diffraction | 1989 |
Thiazostatin A and thiazostatin B, new antioxidants produced by Streptomyces tolurosus.
Topics: Antioxidants; Chemical Phenomena; Chemistry; Streptomyces; Thiazoles; Thiazolidines | 1989 |
Effect of L-thioproline on the progression and events of the cell cycle of HeLa cells.
Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Cyclic AMP; HeLa Cells; Humans; Sodium; Thiazoles; Thiazolidines; Thymidine; Time Factors | 1988 |
Effects of experimentally altered glutathione levels on life span, metabolic rate, superoxide dismutase, catalase and inorganic peroxides in the adult housefly, Musca domestica.
Topics: Animals; Buthionine Sulfoximine; Catalase; Energy Metabolism; Glutathione; Houseflies; Kinetics; Life Expectancy; Methionine Sulfoximine; Peroxides; Pyrrolidonecarboxylic Acid; Superoxide Dismutase; Thiazoles; Thiazolidines | 1985 |
Modulation of gamma-glutamyl cycle and glutathione levels in rat mammary gland explants.
Topics: Amidohydrolases; Animals; Buthionine Sulfoximine; Culture Techniques; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Mammary Glands, Animal; Methionine Sulfoximine; Peptide Synthases; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1986 |
Protection by L-2-oxothiazolidine-4-carboxylate, a cysteine prodrug, against 1,1-dichloroethylene hepatotoxicity in rats is associated with decreases in toxin metabolism and cytochrome P-450.
Topics: Animals; Cytochrome P-450 Enzyme System; Dichloroethylenes; Glutathione; Hydrocarbons, Chlorinated; Liver; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Marked increase of cysteine levels in many regions of the brain after administration of 2-oxothiazolidine-4-carboxylate.
Topics: Animals; Brain; Brain Stem; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cysteine; Glutathione; Hypothalamus; Male; Mice; Pons; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Administration of L-2-oxothiazolidine-4-carboxylate increases glutathione levels in rat brain.
Topics: Animals; Brain; Glutathione; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Macrophage-mediated N-nitrosation of thioproline and proline.
Topics: Animals; Cell Line, Transformed; Macrophage Activation; Macrophages; Mice; Morpholines; Nitrosamines; Proline; Thiazoles; Thiazolidines | 1989 |
[Effect of L-4-thioproline on arrhythmias caused by acute myocardial ischemia in rabbits].
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Female; Male; Rabbits; Thiazoles; Thiazolidines | 1986 |
[Effects of thioproline on isolated guinea pig papillary muscles].
Topics: Animals; Anti-Arrhythmia Agents; Calcium Chloride; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Thiazoles; Thiazolidines; Verapamil | 1986 |
[Effects of thioproline on disturbances of action potentials of the papillary muscles caused by a large dose of lidocaine].
Topics: Action Potentials; Animals; Female; Guinea Pigs; Lidocaine; Male; Papillary Muscles; Thiazoles; Thiazolidines | 1986 |
Effect of aldose reductase inhibitor ONO 2235 on reduced sympathetic nervous system activity and peripheral nerve disorders in STZ-induced diabetic rats.
Topics: Aldehyde Reductase; alpha-Methyltyrosine; Animals; Autonomic Nervous System Diseases; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Erythrocytes; Female; Methyltyrosines; Neural Conduction; Norepinephrine; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Streptozocin; Sugar Alcohol Dehydrogenases; Sympathetic Nervous System; Thiazoles; Thiazolidines; Triiodothyronine | 1987 |
Effects of diverse intracellular thiol delivery agents on glutathione peroxidase activity, the ratio of reduced/oxidized glutathione, and ornithine decarboxylase induction in isolated mouse epidermal cells treated with 12-O-tetradecanoylphorbol-13-acetate
Topics: Acetylcysteine; Animals; Cells, Cultured; Ditiocarb; Epidermis; Female; Glutathione; Glutathione Peroxidase; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1987 |
Effects of aldose reductase inhibitor on the peripheral nerve function during ischemia in diabetics.
Topics: Action Potentials; Adolescent; Adult; Aldehyde Reductase; Arm; Child; Diabetic Neuropathies; Female; Humans; Ischemia; Male; Middle Aged; Peripheral Nerves; Rhodanine; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1987 |
Photo-stabilization and solubilization of an aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodani ne (ONO-2235), by human serum albumin.
Topics: Aldehyde Reductase; Drug Stability; Humans; Photochemistry; Rhodanine; Serum Albumin; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1987 |
[L-thiazolidine-4-carboxylic acid as a source of cysteine in parenteral nutrition].
Topics: Animals; Cysteine; Cystine; Male; Parenteral Nutrition, Total; Rats; Rats, Inbred Strains; Taurine; Thiazoles; Thiazolidines | 1988 |
Glutathione depletion greatly reduces neocarzinostatin cytotoxicity in Chinese hamster V79 cells.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Cysteine; Glutathione; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin | 1985 |
Effects of aldose reductase inhibitor on retinal microangiopathy in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Blood Glucose; Body Weight; Capillaries; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Retinal Vessels; Rhodanine; Streptozocin; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1985 |
The inhibitory effect of thioproline on carcinogenesis induced by N-benzylmethylamine and nitrite.
Topics: Animals; Benzylamines; Carcinoma, Squamous Cell; Male; Nitrites; Rats; Rats, Inbred F344; Stomach Neoplasms; Thiazoles; Thiazolidines | 1988 |
Effects of a cysteine precursor, L-2-oxothiazolidine-carboxylate, nutritional status, and sex on tissue glutathione and hepatic GSH-utilizing enzymes of CD-1 mice.
Topics: Animals; Cytochrome P-450 Enzyme System; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Liver; Male; Mice; Nutritional Status; Pyrrolidonecarboxylic Acid; Sex Factors; Thiazoles; Thiazolidines | 1988 |
Latrunculin A is a potent inhibitor of phagocytosis by macrophages.
Topics: Actin Cytoskeleton; Animals; Antigen-Antibody Complex; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin B; Erythrocytes; Immunoglobulin G; Macrophages; Mice; Phagocytosis; Sheep; Thiazoles; Thiazolidines | 1988 |
The influence of thyroid hormones on colony growth of peripheral CFU-GM from normal and leukemic subjects.
Topics: Cells, Cultured; Flurbiprofen; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia; Monocytes; Thiazoles; Thiazolidines; Thyroid Hormones | 1988 |
Immunotropic compounds. Structure and biological activity of L-cysteine and 1,3-thiazolidine-4-carboxylic acid derivatives.
Topics: Animals; Cysteine; Immunosuppressive Agents; Molecular Conformation; Rats; Thiazoles; Thiazolidines | 1988 |
L-2-oxothiazolidine-4-carboxylate protects cultured endothelial cells against hyperoxia-induced injury.
Topics: Cells, Cultured; Endothelium, Vascular; Glutathione; Oxygen; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1988 |
Intracellular delivery of cysteine.
Topics: Animals; Biological Transport; Cysteine; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Radioisotope Dilution Technique; Sulfur Radioisotopes; Thiazoles; Thiazolidines; Tissue Distribution | 1987 |
Haemodynamic and renal effects of a novel prostaglandin analogue (L644,122(+isomer)) in sheep.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Kidney; Renal Circulation; Renin; Sheep; Thiazoles; Thiazolidines; Vasodilator Agents | 1987 |
A decrease in cysteine levels causes the glutathione deficiency of aging in the mosquito.
Topics: Aedes; Aging; Animals; Antioxidants; Cysteine; Cystine; Glutathione; Glutathione Disulfide; Thiazoles; Thiazolidines | 1988 |
Role of glutathione in the toxicity of the sesquiterpene lactones hymenoxon and helenalin.
Topics: Acetylcysteine; Animals; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Sesquiterpenes; Sesquiterpenes, Guaiane; Thiazoles; Thiazolidines; Toxins, Biological | 1988 |
Contribution of wood smoke to in vivo formation of N-nitrosothiazolidine-4-carboxylic acid: initial studies.
Topics: Acetaldehyde; Animals; Formaldehyde; Male; Nitrosamines; Nitroso Compounds; Rats; Rats, Inbred Strains; Smoke; Thiazoles; Thiazolidines; Wood | 1988 |
The generation of oxygen radicals: a positive signal for lymphocyte activation.
Topics: Animals; Cell Line; Free Radicals; Glutathione; Lymphocyte Activation; Mercaptoethanol; Mice; Oxygen; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Thymoma; Tumor Cells, Cultured | 1988 |
Marked increase in the urinary level of N-nitrosothioproline after ingestion of cod with vegetables.
Topics: Animals; Fishes; Formaldehyde; Half-Life; Humans; Nitrates; Nitroso Compounds; Thiazoles; Thiazolidines; Vegetables | 1988 |
Low toxicity cancer chemotherapy by suicide inactivation of DNA polymerase alpha holoenzyme: first results with new thiazolidinyl- and perhydrothiazinyl-ethyl-N-mustard-phosphamide esters.
Topics: Animals; Antineoplastic Agents; DNA Polymerase II; Kinetics; Leukemia P388; Leukemia, Experimental; Mice; Nitrogen Mustard Compounds; Thiazines; Thiazoles; Thiazolidines | 1988 |
Effects of the thiazolidinedione derivative CGP 19984 on growth and endocrine function of the MtT-W10 transplantable mammosomatotropic pituitary tumor in female rats.
Topics: Animals; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Growth Hormone; Ovariectomy; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1988 |
Effect of dietary protein deficiency and L-2-oxothiazolidine-4-carboxylate on the diurnal rhythm of hepatic glutathione in the rat.
Topics: Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Cysteine; Diet; Glutathione; Liver; Male; Protein Deficiency; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Time Factors | 1988 |
Platelet anti-aggregant activity of 2,2-dimethylthiazolidine hydrochloride and 2-(4-hydroxy-3-methoxyphenyl)thiazolidine.
Topics: Animals; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1988 |
[Inhibition of ovulation by thioproline in immature mice].
Topics: Animals; Female; Mice; Ovulation; Progesterone; Receptors, Gonadotropin; Receptors, LH; Thiazoles; Thiazolidines | 1987 |
Voltage-sensitive dyes measure potential changes in axons and glia of the frog optic nerve.
Topics: Animals; Axons; Benzoxazoles; Electric Stimulation; Electrophysiology; Microelectrodes; Neuroglia; Optic Nerve; Oxazoles; Oxazolone; Rana pipiens; Rhodanine; Thiazoles; Thiazolidines | 1986 |
Motility and centrosomal organization during sea urchin and mouse fertilization.
Topics: Acrosome; Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Female; Fertilization; Fluorescent Antibody Technique; Male; Mice; Microscopy, Electron; Microtubules; Movement; Organoids; Ovum; Sea Urchins; Spermatozoa; Thiazoles; Thiazolidines; Zygote | 1986 |
Inhibition of actin polymerization by latrunculin A.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Kinetics; Polymers; Rabbits; Thiazoles; Thiazolidines | 1987 |
Computer automated structure evaluation of the carcinogenicity of N-nitrosothiazolidine and N-nitrosothiazolidine 4-carboxylic acid.
Topics: Carcinogens; Computers; Models, Molecular; N-Nitrosopyrrolidine; Nitrosamines; Nitroso Compounds; Probability; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1987 |
Experimental human exposure to carbon disulfide. II. Urinary excretion of 2-thiothiazolidine-4-carboxylic acid (TTCA) during and after exposure.
Topics: Adult; Air Pollutants, Occupational; Carbon Disulfide; Creatinine; Environmental Exposure; Humans; Kinetics; Male; Respiration; Thiazoles; Thiazolidines | 1987 |
Effect of a cysteine prodrug (L-2-oxothiazolidine-4-carboxylic acid) on the metabolism and toxicity of bromobenzene: a repeated exposure study.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Glutathione; Inactivation, Metabolic; Male; Metabolic Clearance Rate; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1987 |
Modulation of intracellular glutathione concentrations alters lymphocyte activation and proliferation.
Topics: Acridine Orange; Animals; Buthionine Sulfoximine; Cell Cycle; Concanavalin A; Flow Cytometry; Glutathione; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thymidine | 1987 |
Effect of L-2-oxothiazolidine-4-carboxylate administration on glutathione and cysteine concentrations in guinea pig liver and kidney.
Topics: Animals; Cysteine; Glutathione; Guinea Pigs; Kidney; Kinetics; Liver; Male; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1987 |
Thiazolidine-4-carboxylic acid toxicity and glutathione levels in various organs of the rat.
Topics: Animals; Antineoplastic Agents; Eye; Gastric Mucosa; Glutathione; Liver; Rats; Rats, Inbred Strains; Stomach; Thiazoles; Thiazolidines | 1987 |
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1987 |
Induction of metallothionein in rat primary hepatocyte cultures: evidence for direct and indirect induction.
Topics: Animals; Cells, Cultured; Dexamethasone; Ethanol; Liver; Metallothionein; Metals; Potassium; Protein Biosynthesis; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Urethane | 1987 |
Roles of cysteine as both precursor of thiazolidine 4-carboxylic acids found in human urine and possible inhibitor of endogenous N-nitrosation.
Topics: Cysteine; Fourier Analysis; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Nitroso Compounds; Thiazoles; Thiazolidines | 1987 |
Effect of cigarette smoking and dietary factors on the amount of N-nitrosothiazolidine 4-carboxylic acid and N-nitroso-2-methyl-thiazolidine 4-carboxylic acid in human urine.
Topics: Adult; Diet; Female; Humans; Male; Nitroso Compounds; Sex Factors; Smoking; Thiazoles; Thiazolidines | 1987 |
Urinary excretion of N-nitrosamino acids and nitrate by inhabitants in high- and low-risk areas for stomach cancer in northern Japan.
Topics: Ascorbic Acid; Chlorides; Feeding Behavior; Humans; Japan; Nitrates; Nitrosamines; Nitroso Compounds; Risk Factors; Smoking; Stomach Neoplasms; Thiazoles; Thiazolidines | 1987 |
[Thioproline poisoning and generalized convulsive crisis].
Topics: Adult; Electroencephalography; Female; Humans; Seizures; Thiazoles; Thiazolidines | 1986 |
Intracellular cysteine and glutathione delivery systems.
Topics: Acetaminophen; Animals; Biological Transport, Active; Cysteine; Dipeptides; Glutathione; Intracellular Fluid; Kidney; Liver; Mice; Models, Biological; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Sulfur; Thiazoles; Thiazolidines | 1986 |
Enhancement of intracellular glutathione promotes lymphocyte activation by mitogen.
Topics: Animals; Buthionine Sulfoximine; Glutathione; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mitogens; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1986 |
Latrunculin inhibits the microfilament-mediated processes during fertilization, cleavage and early development in sea urchins and mice.
Topics: Acrosome; Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Embryo, Mammalian; Embryo, Nonmammalian; Female; Fertilization; Horseshoe Crabs; Male; Mice; Oocytes; Ovum; Sea Urchins; Spermatozoa; Thiazoles; Thiazolidines | 1986 |
Helenalin: mechanism of toxic action.
Topics: Animals; Drug Interactions; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Pyrrolidonecarboxylic Acid; Sesquiterpenes; Sesquiterpenes, Guaiane; Thiazoles; Thiazolidines; Toxins, Biological | 1986 |
Glutathione-dependent toxicity of the algicide 1-chloro-2,4-dinitrobenzene to Daphnia magna Straus.
Topics: Animals; Daphnia; Dinitrochlorobenzene; Glutathione; Pesticides; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1986 |
Correction of a glutathione deficiency in the aging mosquito increases its longevity.
Topics: Aedes; Aging; Animals; Glutathione; Longevity; Thiazoles; Thiazolidines | 1987 |
The influence of simultaneous exposure to carbon disulfide and hydrogen sulfide on the peripheral nerve toxicity and metabolism of carbon disulfide in rats.
Topics: Animals; Body Weight; Carbon Disulfide; Hydrogen Sulfide; Male; Neural Conduction; Peripheral Nerves; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1986 |
Time-lapse microcinematography of the effect of thiazolidine carboxylic acid (thioproline) upon tissue cultures.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Contact Inhibition; HeLa Cells; Humans; KB Cells; Microfilming; Thiazoles; Thiazolidines | 1985 |
[Effects of thiazolidine-4-carboxylic acid on germ tube formation and L-[14C(U)] proline uptake in Candida albicans].
Topics: Antineoplastic Agents; Candida albicans; Culture Media; Dose-Response Relationship, Drug; Proline; Thiazoles; Thiazolidines | 1985 |
Synthesis of L-2-oxothiazolidine-4-carboxylic acid.
Topics: Indicators and Reagents; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Radioisotope Dilution Technique; Sulfur Radioisotopes; Thiazoles; Thiazolidines | 1985 |
Effects of a fructose-rich diet and the aldose reductase inhibitor, ONO-2235, on the development of diabetic neuropathy in streptozotocin-treated rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Carbohydrates; Erythrocytes; Fructose; Male; Motor Neurons; Neural Conduction; Rats; Retina; Rhodanine; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1985 |
[Experimentally induced diabetic retinal microangiopathy and polyol pathway. II. Effect of aldose reductase inhibitors on microangiopathy].
Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Male; Rats; Rats, Inbred Strains; Rhodanine; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1985 |
Antitumor efficacy in rats of CGP 19984, a thiazolidinedione derivative that inhibits luteinizing hormone secretion.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Castration; Corticosterone; Female; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prolactin; Prostatic Neoplasms; Rats; Rats, Inbred F344; Testosterone; Thiazoles; Thiazolidines | 1986 |
Increase in the levels of N-nitrosoproline, N-nitrosothioproline and N-nitroso-2-methylthioproline in human urine by cigarette smoking.
Topics: Chromatography, Gas; Diet; Humans; Male; Middle Aged; Nitrosamines; Nitroso Compounds; Smoking; Thiazoles; Thiazolidines; Time Factors | 1986 |
Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteine; Glucuronates; Glucuronic Acid; Glutathione; Kinetics; Liver; Liver Glycogen; Male; Mice; Phosphoadenosine Phosphosulfate; Protein Binding; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1986 |
Enhancement of intracellular glutathione protects endothelial cells against oxidant damage.
Topics: Animals; Buthionine Sulfoximine; Cattle; Endothelium; Glucose Oxidase; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1985 |
The effects of cellular glutathione elevation on the oxygen enhancement ratio.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Glutathione; In Vitro Techniques; Oxygen; Pyrrolidonecarboxylic Acid; Stimulation, Chemical; Thiazoles; Thiazolidines | 1985 |
Evaluation of occupational exposure to carbon disulphide by blood, exhaled air, and urine analysis.
Topics: Adult; Breath Tests; Carbon Disulfide; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Occupational Diseases; Thiazoles; Thiazolidines | 1985 |
Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione modulation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Free Radicals; Glutathione; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1985 |
Treatment of cancer by an inducer of reverse transformation.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carboxylic Acids; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Neoplasms; Thiazoles; Thiazolidines | 1980 |
Thioproline.
Topics: Administration, Oral; Child; Humans; Injections, Intravenous; Neoplasms; Thiazoles; Thiazolidines | 1980 |
Thioproline.
Topics: Animals; Cell Membrane; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1980 |
Thioproline in squamous cell cancer.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Psychoses, Substance-Induced; Thiazoles; Thiazolidines | 1980 |
Effect of arginine salt of thioproline (thiazolidine carboxylate) on cyclic nucleotides of cerebral tumour.
Topics: Arginine; Brain Chemistry; Brain Neoplasms; Cyclic AMP; Cyclic GMP; Humans; Thiazoles; Thiazolidines | 1980 |
Thioproline and reversal of cancer.
Topics: Antineoplastic Agents; Humans; Neoplasms; Thiazoles; Thiazolidines | 1983 |
Renal vasodilation by a prostaglandin analog during dopaminergic and alpha-adrenergic blockade.
Topics: Animals; Aporphines; Blood Flow Velocity; Blood Pressure; Dinoprostone; Dogs; Dopamine; Female; Male; Phenoxybenzamine; Prostaglandins E; Renal Circulation; Thiazoles; Thiazolidines; Vascular Resistance; Vasodilator Agents | 1983 |
A comparison of some renal and cardiovascular effects of a prostaglandin analog, SKF 82526 and ibopamine in anesthetized dogs.
Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Deoxyepinephrine; Dogs; Dopamine; Electrolytes; Female; Fenoldopam; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Phenoxybenzamine; Renal Circulation; Thiazoles; Thiazolidines; Vasodilator Agents | 1984 |
Effect of H2 blockers on intragastric nitrosation as measured by 24-hour urinary secretion of N-nitrosoproline.
Topics: Adult; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Male; Middle Aged; Nitrosamines; Nitroso Compounds; Proline; Ranitidine; Thiazoles; Thiazolidines | 1984 |
Effects of an orally active converting enzyme inhibitor (YS-980) on renal function in dogs.
Topics: 3-Mercaptopropionic Acid; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Dogs; Hemodynamics; Indomethacin; Kallikreins; Kidney; Kinins; Prostaglandins; Regional Blood Flow; Renin; Sulfhydryl Compounds; Teprotide; Thiazoles; Thiazolidines | 1980 |
Further studies on absorption changes arising in dye-stained nerves during excitation.
Topics: Animals; Benzoxazoles; Brachyura; Electric Stimulation; Ganglia, Sympathetic; Light; Nerve Fibers; Rabbits; Rats; Rhodanine; Spectrophotometry; Staining and Labeling; Thiazoles; Thiazolidines; Vagus Nerve | 1980 |
Alteration of bleomycin cytotoxicity by glutathione depletion or elevation.
Topics: Animals; Bleomycin; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors | 1984 |
Effect of various sulfur compounds on the transport system enzymes in human erythrocyte membranes.
Topics: Acetophenones; Acetylcholinesterase; Adenosine Triphosphatases; Biological Transport; Dimethyl Sulfoxide; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Sulfur; Thiazoles; Thiazolidines | 1982 |
[Effects of thioproline on experimental arrhythmia].
Topics: Animals; Anti-Arrhythmia Agents; Antineoplastic Agents; Arrhythmias, Cardiac; Dogs; Female; Guinea Pigs; Male; Mice; Rabbits; Rats; Thiazoles; Thiazolidines | 1984 |
Inhibitor of angiotensin I converting enzyme: (4R)-3-[(2S)-3-mercapto-2-methylpropanoyl]-4-thiazolidinecarboxylic acid (YS-980).
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; In Vitro Techniques; Kinetics; Norepinephrine; Pentobarbital; Pentolinium Tartrate; Rabbits; Renin; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1980 |
Antihypertensive effects of the novel converting-enzyme inhibitor YS 980 in spontaneously hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bradykinin; Catecholamines; Hypertension; Male; Rats; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1981 |
Effects of YS-980, an orally active converting enzyme inhibitor, on blood pressure in normotensive and hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1981 |
Lack of reverse transformation after treatment of A 549 human alveolar carcinoma cells with thioproline.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Phenotype; Thiazoles; Thiazolidines | 1983 |
Circus-movement tachycardia in frog atrium monitored by voltage-sensitive dyes.
Topics: Acetylcholine; Action Potentials; Animals; Benzoxazoles; Fluorescent Dyes; Heart; Heart Atria; Microelectrodes; Rana catesbeiana; Rhodanine; Tachycardia; Thiazoles; Thiazolidines | 1984 |
In vitro synergy of actithiazic acid, an antimetabolite of biotin, combined with cephalexin.
Topics: Anti-Bacterial Agents; Biotin; Caproates; Cephalexin; Drug Synergism; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Thiazoles; Thiazolidines | 1983 |
Reversal of indomethacin-induced decreases in renal function by an isosterically-modified prostaglandin analog.
Topics: Animals; Diuresis; Dogs; Drug Interactions; Female; Glomerular Filtration Rate; Indomethacin; Kidney; Natriuresis; Regional Blood Flow; Renin; Thiazoles; Thiazolidines | 1983 |
Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds.
Topics: Animals; Carbachol; Cats; Dinoprost; Dinoprostone; Epoprostenol; Female; Intraocular Pressure; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins F, Synthetic; Thiazoles; Thiazolidines; Timolol | 1984 |
Effect of a new aldose reductase inhibitor, (E)-3-carboxymethyl-5-[(2E)-methyl-3-phenylpropenylidene]rhodanine (ONO-2235) on peripheral nerve disorders in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Erythrocytes; Insulin; Male; Neural Conduction; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1983 |
Prevention of peripheral nerve dysfunction by an aldose reductase inhibitor in streptozotocin-diabetic rats.
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Motor Neurons; Neural Conduction; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1984 |
Effects of a new aldose reductase inhibitor on various tissues in vitro.
Topics: Aldehyde Reductase; Animals; Erythrocytes; Kinetics; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Rhodanine; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Thiazoles; Thiazolidines | 1984 |
Radiation response of Chinese hamster cells after elevation of intracellular glutathione levels.
Topics: Aerobiosis; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cobalt; Cricetinae; Cricetulus; Cysteamine; Dose-Response Relationship, Radiation; Glutathione; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines | 1984 |
Pilot study on the treatment with thioproline of 24 small animals with tumors.
Topics: Animals; Antineoplastic Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Female; Injections, Subcutaneous; Male; Neoplasms; Pilot Projects; Thiazoles; Thiazolidines | 1984 |
Inhibition of glutathione efflux in the recirculating rat liver perfusion by cysteine but not by oxothiazolidine carboxylate, an intracellular cysteine precursor.
Topics: Animals; Cysteine; Glutathione; In Vitro Techniques; Kinetics; Liver; Male; Perfusion; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1984 |
Kinetics of nitrosation of thioproline, the precursor of a major nitroso compound in human urine, and its role as a nitrite scavenger.
Topics: Antineoplastic Agents; Carcinogens; Dimethylnitrosamine; Humans; Hydrogen-Ion Concentration; Kinetics; Nitrites; Nitroso Compounds; Thiazoles; Thiazolidines | 1984 |
Drugs affecting the hormonal receptors of normal and leukaemic peripheral leucocytes.
Topics: Estradiol; Estriol; Flurbiprofen; Humans; Hydrocortisone; In Vitro Techniques; Leukemia; Leukocytes; Receptors, Steroid; Testosterone; Theophylline; Thiazoles; Thiazolidines | 1984 |
Cardiovascular responses to an isosterically modified prostaglandin analog in conscious dogs.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiovascular Physiological Phenomena; Dogs; Female; Heart Rate; Kinetics; Male; Nitroprusside; Stroke Volume; Thiazoles; Thiazolidines; Time Factors; Vascular Resistance; Vasodilator Agents | 1984 |
Formation of 2-methyl-2,4-thiazolidinedicarboxylic acid from L-cysteine in rat tissues.
Topics: Animals; Biotransformation; Cystathionine gamma-Lyase; Cysteine; Hydrogen-Ion Concentration; In Vitro Techniques; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines; Time Factors; Tissue Distribution | 1984 |
[Hydroelactic and ecbolic of piprozoline on basal bile-pancreatic secretion in rats].
Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Bilirubin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Pancreas; Pancreatic Fistula; Rats; Secretin; Thiazoles; Thiazolidines | 1984 |
N-nitrosoproline in urine from patients and healthy volunteers after administration of large amounts of nitrate.
Topics: Humans; Nitrates; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1984 |
Modulation of endogenous synthesis of N-nitrosamino acids in humans.
Topics: Adult; Ascorbic Acid; Humans; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines; Vitamin E | 1984 |
Presence in human urine of new sulfur-containing N-nitrosamino acids: N-nitrosothiazolidine 4-carboxylic acid and N-nitroso 2-methylthiazolidine 4-carboxylic acid.
Topics: Chemical Phenomena; Chemistry; Cysteine; Humans; Nitroso Compounds; Smoking; Thiazoles; Thiazolidines | 1984 |
A new type of N-nitrosamino acid, N-nitroso-L-thioproline and N-nitroso-L-methylthioprolines, found in human urine as major N-nitroso compounds.
Topics: Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1984 |
N-nitrosamines in smoked meats and their relation to diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diet; Dimethylnitrosamine; Food Preservation; Meat; Mice; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1984 |
Recent studies on N-nitroso compounds as possible etiological factors in oesophageal cancer.
Topics: Africa; Beverages; China; Esophageal Neoplasms; Humans; Iran; Nitrates; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 1984 |
In-vivo nitrosation, precancerous lesions and cancers of the gastrointestinal tract. On-going studies and preliminary results.
Topics: Anemia, Pernicious; Cimetidine; Gastrectomy; Gastritis, Atrophic; Humans; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Stomach Neoplasms; Thiazoles; Thiazolidines | 1984 |
Monitoring endogenous nitrosamine formation in man.
Topics: Animals; Environmental Monitoring; Feces; Humans; Kinetics; Mice; Neoplasms, Experimental; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Rats; Risk; Thiazoles; Thiazolidines | 1984 |
Antitumor studies of 2-amino-2-thiazoline and other tumor-modifying agents.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line; Dimethylhydrazines; Female; Methylcholanthrene; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1983 |
[Distribution of electric charges in 2 substances inducing tumor cell regression].
Topics: Antineoplastic Agents; Electrochemistry; Thiazoles; Thiazolidines | 1983 |
Presence in human urine of a new N-nitroso compound, N-nitrosothiazolidine 4-carboxylic acid.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Cysteine; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; Nitrates; Nitroso Compounds; Thiazoles; Thiazolidines | 1983 |
[New research on the cellular effects of thiaproline].
Topics: Animals; Antineoplastic Agents; Female; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitosis; Thiazoles; Thiazolidines | 1983 |
Assessment of endogenous nitrosation in humans in relation to the risk of cancer of the digestive tract.
Topics: Ascorbic Acid; Dose-Response Relationship, Drug; Esophageal Neoplasms; Gastrointestinal Neoplasms; Humans; Kinetics; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Proline; Risk; Thiazoles; Thiazolidines | 1983 |
Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Fibroblasts; Marine Toxins; Microscopy, Fluorescence; Microtubules; Neuroblastoma; Thiazoles; Thiazolidines | 1983 |
Urinary excretion products of formaldehyde in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cysteine; Formaldehyde; Mass Spectrometry; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1984 |
Mechanism of chloroform nephrotoxicity. IV. Phenobarbital potentiation of in vitro chloroform metabolism and toxicity in rabbit kidneys.
Topics: Animals; Chloroform; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Diseases; Male; Microsomes; p-Aminohippuric Acid; Phenobarbital; Phosgene; Pyrrolidonecarboxylic Acid; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Thiazoles; Thiazolidines | 1984 |
Synthesis of L-2-oxothiazolidine-4-carboxylic acid.
Topics: Chlorobenzoates; Glutathione; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1984 |
Relation between the iodine azide test and the TTCA test for exposure to carbon disulphide.
Topics: Azides; Carbon Disulfide; Environmental Exposure; Humans; Iodine; Occupational Medicine; Sodium Azide; Thiazoles; Thiazolidines | 1984 |
Occurrence in human urine of new sulphur-containing N-nitrosamino acids N-nitrosothiazolidine 4-carboxylic acid and its 2-methyl derivative, and their formation.
Topics: Administration, Oral; Animals; Ascorbic Acid; Humans; Hydrogen-Ion Concentration; Male; Nitrosamines; Nitroso Compounds; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1984 |
Accelerated aging of fasted Drosophila. Preservation of physiological function and cellular fine structure by thiazolidine carboxylic acid (TCA).
Topics: Aging; Animals; Antioxidants; Dose-Response Relationship, Drug; Drosophila melanogaster; Fasting; Female; Glycogen; Male; Muscles; Oxygen Consumption; Sexual Behavior, Animal; Thiazoles; Thiazolidines | 1982 |
Antioxidants, metabolic rate and aging in Drosophila.
Topics: 2,4-Dinitrophenol; Animals; Antioxidants; Catechols; Dinitrophenols; Drosophila melanogaster; Longevity; Masoprocol; Metabolism; Oxygen Consumption; Thiazoles; Thiazolidines; Vitamin E | 1982 |
Prostaglandin isosteres. 2. Chain-modified thiazolidinone prostaglandin analogues as renal vasodilators.
Topics: Animals; Dogs; Female; Kidney; Models, Molecular; Regional Blood Flow; Stereoisomerism; Thiazoles; Thiazolidines; Vascular Resistance; Vasodilation; X-Ray Diffraction | 1983 |
Presence of N-nitroso-L-thioproline and N-nitroso-L-methylthioprolines in human urine as major N-nitroso compounds.
Topics: Chromatography, Gas; Humans; Nitroso Compounds; Thiazoles; Thiazolidines | 1983 |
Relationship between metabolism and radioprotective activity of 2-phenylthiazolidine and its m-bromo derivative.
Topics: Animals; Benzaldehydes; Biotransformation; Chromatography, Thin Layer; Cysteamine; Mice; Radiation-Protective Agents; Thiazoles; Thiazolidines | 1983 |
Effect of thiazolidine-4-carboxylic acid (Thioproline) on sister chromatid exchanges in CHO cells and human lymphocytes, and on the kinetics of human lymphocytes in vitro.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cells, Cultured; Contact Inhibition; Cricetinae; Crossing Over, Genetic; Depression, Chemical; Female; Humans; In Vitro Techniques; Lymphocytes; Ovary; Sister Chromatid Exchange; Thiazoles; Thiazolidines | 1982 |
[Diminution of the rate of growth of HeLa cells caused by thioproline (Tp) and 2-aminothiazoline HCl (2-AT). Effect of L-proline].
Topics: Growth Inhibitors; HeLa Cells; Humans; Proline; Thiazoles; Thiazolidines | 1982 |
[Transrecters. A new group of inducers of reverse transformation with possible use in the treatment of human cancer].
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; HeLa Cells; Humans; Neoplasms; Thiazoles; Thiazolidines | 1982 |
Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrate.
Topics: Amidohydrolases; Animals; Glutathione; Kidney; Kinetics; Liver; Mice; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1981 |
Maturation of human peripheral blood leukemic cells in short-term culture.
Topics: Cell Count; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Neutrophils; Prostaglandins A; Thiazoles; Thiazolidines; Time Factors | 1981 |
Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis.
Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Synthase; Inactivation, Metabolic; Liver; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1982 |
Optical recording of conducted action potential in heart muscle using a voltage-sensitive dye.
Topics: Action Potentials; Animals; Benzoxazoles; Coloring Agents; Heart; In Vitro Techniques; Methods; Optics and Photonics; Rana catesbeiana; Rhodanine; Thiazoles; Thiazolidines | 1981 |
Mode of action of the biotin antimetabolites actithiazic acid and alpha-methyldethiobiotin.
Topics: Anti-Bacterial Agents; Antimetabolites; Biotin; Caproates; Escherichia coli; Thiazoles; Thiazolidines | 1982 |
Phase II trial of thioproline in advanced epidermoid head and neck tumors.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nervous System Diseases; Thiazoles; Thiazolidines | 1982 |
Studies on the relationship between the survival of Schistosoma mansoni larvae in mice and the degree of resistance produced.
Topics: Animals; Antigens, Surface; Female; Immunization; Larva; Male; Mice; Mice, Inbred CBA; Niridazole; Oxamniquine; Schistosoma mansoni; Schistosomiasis; Thiazoles; Thiazolidines; Time Factors | 1982 |
[Thiazolidine carboxylic acid toxicity. A review of 78 cases (author's transl)].
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Female; Humans; Infant; Male; Rats; Retrospective Studies; Thiazoles; Thiazolidines | 1982 |
Fasciolicidal potential of proline analogues and proline biosynthesis inhibitors.
Topics: Animals; Azetidinecarboxylic Acid; Fasciola; Fascioliasis; Female; Hydroxylamine; Hydroxylamines; Proline; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1982 |
An orally active prostaglandin analog with renal vasodilatory activity in the dog.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Female; Heart Rate; Male; Prostaglandins, Synthetic; Renal Circulation; Thiazoles; Thiazolidines; Time Factors; Vasodilator Agents | 1982 |
Excretion of TTCA in human urine after administration of disulfiram.
Topics: Adult; Carbon Disulfide; Disulfiram; Humans; Male; Thiazoles; Thiazolidines | 1982 |
Acute thioproline poisoning.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; France; Humans; Infant; Male; Seizures; Thiazoles; Thiazolidines | 1982 |
The metabolism of benzyl isothiocyanate and its cysteine conjugate in guinea-pigs and rabbits.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Cysteine; Guinea Pigs; Isothiocyanates; Magnetic Resonance Spectroscopy; Male; Rabbits; Thiazoles; Thiazolidines; Thiocyanates | 1982 |
[Effects of L-thiazolidine-4-carboxylic acid (thiaproline) on cancer cells in culture].
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1982 |
Preliminary evaluation of urinary 2-thio-thiazolidine-4-carboxylic-acid (TTCA) levels as a test for exposure to carbon disulfide.
Topics: Adult; Air; Carbon Disulfide; Creatine; Environmental Exposure; Humans; Middle Aged; Thiazoles; Thiazolidines; Time Factors | 1982 |
Thioproline: an inhibitor of chemical carcinogenesis.
Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Female; Methylcholanthrene; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Thiazoles; Thiazolidines | 1982 |
On the irreproducibility of thioproline.
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Synergism; HeLa Cells; Humans; Thiazoles; Thiazolidines | 1982 |
Effect of arginine thiazolidinecarboxylate on allyl alcohol hepatotoxicity in the rat.
Topics: 1-Propanol; Alanine Transaminase; Alkaline Phosphatase; Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Kinetics; Propanols; Rats; Thiazoles; Thiazolidines | 1981 |
Thioproline (Norgamem): a useless drug in the treatment of squamous cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Head and Neck Neoplasms; Humans; Lung Neoplasms; Thiazoles; Thiazolidines | 1981 |
Reverse transformation agent and their ability to complex metal ions.
Topics: Ligands; Metals; Thiazoles; Thiazolidines | 1981 |
[Experiment comparative clinical study with three liver trophical substances on some alcoholic not cirrhotic liver disease (author's transl)].
Topics: Adult; Aged; Arginine; Cyclohexanecarboxylic Acids; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Phosphatidylcholines; Thiazoles; Thiazolidines | 1980 |
[Further clinical observations on the treatment of noncirrhotic alcoholic liver disease].
Topics: Adult; Aged; Arginine; Cyclohexanecarboxylic Acids; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Phosphatidylcholines; Thiazoles; Thiazolidines | 1980 |
The effect of thioproline on transplanted tumors in nude mice.
Topics: Animals; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Thiazoles; Thiazolidines; Transplantation, Heterologous | 1980 |
Localization of pacemaking activity in early embryonic heart monitored using voltage-sensitive dye.
Topics: Action Potentials; Animals; Chick Embryo; Fluorescent Dyes; Heart; Heart Atria; Heart Rate; Myocardial Contraction; Pyrimidines; Rhodanine; Thiazoles; Thiazolidines | 1981 |
[Value of the use of a new hepatotropic drug, arginine tidiacicate in gastroenterology. Results of a multicentric study].
Topics: Adult; Aged; Arginine; Female; Gastrointestinal Diseases; Humans; Liver Diseases; Male; Middle Aged; Thiazoles; Thiazolidines | 1981 |
Arginine thiazolidinecarboxylate 14C uptake by individual phospholipids isolated from rat liver microsomes.
Topics: Animals; Arginine; Carbon Radioisotopes; Male; Microsomes, Liver; Phospholipids; Rats; Thiazoles; Thiazolidines | 1981 |
Determination of thioproline in plasma using high performance liquid chromatography.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Humans; Neoplasms; Thiazoles; Thiazolidines | 1981 |
Acute poisoning with thiazolidine carboxylic acid.
Topics: Anticonvulsants; Child, Preschool; Humans; Male; Physostigmine; Seizures; Thiazoles; Thiazolidines | 1981 |
[Tissue distribution of carbon-14 following oral administration of 14C-arginine thiazolidinecarboxylate in rats].
Topics: Animals; Arginine; Rats; Thiazoles; Thiazolidines; Tissue Distribution | 1981 |
Identification and determination of 2-thiothiazolidine-4-carboxylic acid in urine of workers exposed to carbon disulfide.
Topics: Carbon Disulfide; Carboxylic Acids; Chromatography, High Pressure Liquid; Environmental Exposure; Humans; Occupational Medicine; Sulfhydryl Compounds; Textile Industry; Thiazoles; Thiazolidines | 1981 |
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes | 1981 |
Studies on peptides. CII. Synthesis of a heptacosapeptide amide corresponding to the entire amino acid sequence of gastrin-releasing peptide.
Topics: Amino Acid Sequence; Animals; Biological Assay; Bombesin; Dogs; Gastrin-Releasing Peptide; Gastrins; Gastrointestinal Hormones; Peptide Fragments; Peptides; Thiazoles; Thiazolidines | 1981 |
[Effect of thiobiline in the treatment of functional digestive disorders].
Topics: Biliary Dyskinesia; Digestive System Diseases; Drug Combinations; Dyspepsia; Humans; Sorbitol; Thiazoles; Thiazolidines | 1981 |
[Protective effect of arginine thiazolidinecarboxylate on morphological and functional changes in the liver induced by chronic ethanol intoxication in the rat].
Topics: Animals; Arginine; Liver Diseases, Alcoholic; Rats; Thiazoles; Thiazolidines | 1980 |
[Normalizing effect of arginine thiazolidincarboxylate (ATCA) on hepatocytes in CCL4 poisoning in rats].
Topics: Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Male; Rats; Thiazoles; Thiazolidines | 1980 |
[Transmethylating activity of arginine thiazolidinecarboxylate (ATCA) in acute CCL4 poisoning and diet-induced steatosis in the rat].
Topics: Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diet; Fatty Liver; Male; Methylation; Rats; Thiazoles; Thiazolidines | 1980 |
[Activity of arginine thiazolidin carboxylate on the acute poisoning by paracetamol in mice].
Topics: Acetaminophen; Animals; Arginine; Liver; Male; Mice; Thiazoles; Thiazolidines | 1980 |
In vivo selective modulation of tissue glutathione in a rat mammary carcinoma model.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Buthionine Sulfoximine; Drug Synergism; Female; Glutathione; Kidney; Liver; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1995 |
Increased nitrosamine and nitrate biosynthesis mediated by nitric oxide synthase induced in hamsters infected with liver fluke (Opisthorchis viverrini).
Topics: Amino Acid Oxidoreductases; Animals; Carps; Cricetinae; Immunohistochemistry; Liver; Male; Mesocricetus; Nitrates; Nitric Oxide Synthase; Nitrosamines; Nitroso Compounds; Opisthorchiasis; Opisthorchis; Thiazoles; Thiazolidines | 1994 |
Gene expression for interleukin-2 and tumor necrosis factor-alpha in the spleen of old rats under physiological condition and during septic shock. Possible pharmacological modulation.
Topics: Aging; Animals; Blotting, Northern; Gene Expression Regulation; Immunologic Factors; Interleukin-2; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA; Shock, Septic; Spleen; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha | 1994 |
The state of actin assembly regulates actin and vinculin expression by a feedback loop.
Topics: 3T3 Cells; Actin Cytoskeleton; Actins; Animals; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Feedback; HeLa Cells; Humans; Mice; Phalloidine; Polymers; Protein Processing, Post-Translational; RNA; Thiazoles; Thiazolidines; Vinculin | 1995 |
Growth regulation by cell shape alteration and organization of the cytoskeleton.
Topics: Actin Cytoskeleton; Alkaloids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Division; Cell Size; Cells, Cultured; Cytochalasin D; Deoxyribonuclease I; DNA; Epithelial Cells; Fibroblasts; Gelsolin; Humans; Interphase; LLC-PK1 Cells; Microinjections; Protein Biosynthesis; RNA; Swine; Thiazoles; Thiazolidines | 1995 |
Role of platelet-activating factor in the release of neutrophil and eosinophil chemotactic attractants from cultured guinea-pig tracheal epithelial cells.
Topics: Animals; Chemotactic Factors; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Guinea Pigs; Male; Neutrophils; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Trachea | 1995 |
Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs.
Topics: Acetylcysteine; Antioxidants; Dose-Response Relationship, Drug; Drug Interactions; Expectorants; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Hypochlorous Acid; Mesna; Reactive Oxygen Species; Respiratory Burst; Superoxides; Thiazoles; Thiazolidines | 1995 |
Liquid chromatographic determination of urinary 2-thiothiazolidine-4-carboxylic acid, a biomarker of carbon disulphide exposure.
Topics: Biomarkers; Carbon Disulfide; Chromatography, High Pressure Liquid; Humans; Occupational Exposure; Reproducibility of Results; Spectrophotometry, Ultraviolet; Textile Industry; Thiazoles; Thiazolidines | 1995 |
Marked increase in urinary excretion of nitrate and N-nitrosothioproline in the osteogenic disordered syndrome rats, lacking ascorbic acid biosynthesis, by administration of lipopolysaccharide and thioproline.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Bone Diseases; Female; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroso Compounds; Rats; Thiazoles; Thiazolidines | 1995 |
The modulation of IL-2 dependent proliferation of CTLL-2 cells by 2-methyl-thiazolidine-2,4-dicarboxylic acid.
Topics: Adjuvants, Immunologic; Animals; B-Lymphocytes; Cell Division; Cell Line; Cell Survival; Cysteine; Extracellular Space; Interleukin-2; Intracellular Fluid; Lymphoma, T-Cell; Mice; Sulfhydryl Compounds; T-Lymphocytes, Cytotoxic; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1995 |
Efficacy of radioprotective agents in preventing small and large bowel radiation injury.
Topics: Adenosine Triphosphate; Amifostine; Animals; Cysteine; Drug Therapy, Combination; Glutamine; Intestine, Large; Intestine, Small; Magnesium Chloride; Male; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vitamin E | 1995 |
Carbon disulphide. II. Investigations on the uptake of CS2 and the excretion of its metabolite 2-thiothiazolidine-4-carboxylic acid after occupational exposure.
Topics: Adult; Carbon Disulfide; Chemical Industry; Environmental Monitoring; Humans; Linear Models; Male; Middle Aged; Occupational Exposure; Skin Absorption; Skin Diseases; Thiazoles; Thiazolidines | 1995 |
The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes.
Topics: Calcium; Cell Membrane; Centrifugation, Density Gradient; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukocytes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1995 |
Effect of YM264 on the airway hyperresponsiveness and the late asthmatic response in a guinea pig model of asthma.
Topics: Aerosols; Airway Resistance; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; Immunization; Male; Ovalbumin; Piperazines; Platelet Activating Factor; Random Allocation; Statistics, Nonparametric; Thiazoles; Thiazolidines; Time Factors; Trachea | 1995 |
Increased endogenous N-nitrosamine and nitrate formation by induction of nitric oxide synthase in rats with acute hepatic injury caused by Propionibacterium acnes and lipopolysaccharide administration.
Topics: Amino Acid Oxidoreductases; Animals; Disease Models, Animal; Enzyme Induction; Lipopolysaccharides; Liver Diseases; Male; Necrosis; Nitrates; Nitric Oxide Synthase; Nitrosamines; Nitroso Compounds; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1993 |
The role of platelet-activating factor on histamine hypersensitivity in nasal allergy in guinea pig models.
Topics: Allergens; Animals; Guinea Pigs; Histamine Release; Hypersensitivity; Male; Ovalbumin; Platelet Activating Factor; Thiazoles; Thiazolidines | 1993 |
Ethanol-induced changes in the content of thiol compounds and of lipid peroxidation in livers and brains from mice: protection by thiazolidine derivatives.
Topics: Alcoholism; Animals; Antioxidants; Brain; Cysteine; Glutathione; Lipid Peroxidation; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Malondialdehyde; Mice; Thiazoles; Thiazolidines | 1994 |
Effect of cytochrome P450 isozyme induction and glutathione depletion on the metabolism of CS2 to TTCA in rats.
Topics: Administration, Inhalation; Animals; Carbon Disulfide; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Male; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1995 |
L-2-oxothiazolidine-4-carboxylate, a cysteine precursor, stimulates growth and normalizes tissue glutathione concentrations in rats fed a sulfur amino acid-deficient diet.
Topics: Amino Acids, Sulfur; Animals; Bronchoalveolar Lavage Fluid; Diet; Glutathione; Growth; Liver; Lung; Lymphocytes; Male; Pyrrolidonecarboxylic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Weight Gain | 1995 |
Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Dogs; Drug Interactions; Glutathione; Humans; Kidney; Kidney Tubules, Proximal; LLC-PK1 Cells; Mercury Compounds; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Spectrophotometry, Atomic; Swine; Thiazoles; Thiazolidines | 1995 |
A method for determination of total glutathione and total cysteine as S-carboxymethyl derivatives by using an amino acid analyzer, and its application to samples from rat liver, kidney and blood after intraperitoneal administration of 2-(4-carboxy-D-gluco
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Injections, Intraperitoneal; Kidney; Liver; Male; Rats; Rats, Wistar; Spectrophotometry; Thiazoles; Thiazolidines | 1995 |
Sequencing analysis of mutation points in the biotin operon of biotin-overproducing Escherichia coli mutants.
Topics: Base Sequence; Biotin; Caproates; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Molecular Sequence Data; Operon; Pentanoic Acids; Point Mutation; Restriction Mapping; Sequence Analysis, DNA; Thiazoles; Thiazolidines | 1993 |
Dietary habits, a non-negligible source of 2-thiothiazolidine-4-carboxylic acid and possible overestimation of carbon disulfide exposure.
Topics: Biomarkers; Brassica; Carbon Disulfide; Chromatography, High Pressure Liquid; Diet; Environmental Monitoring; Humans; Mass Spectrometry; Occupational Exposure; Thiazoles; Thiazolidines; Urinalysis | 1994 |
Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication.
Topics: Acetylcysteine; Antimetabolites; Antioxidants; Antiviral Agents; Buthionine Sulfoximine; Cells, Cultured; Free Radical Scavengers; Gene Expression Regulation, Viral; Genes, Reporter; Glutathione; HIV Long Terminal Repeat; HIV-1; Humans; Leukocytes, Mononuclear; Methionine Sulfoximine; Monocytes; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha; Virus Replication | 1994 |
L-2-oxothiazolidine-4-carboxylic acid (procysteine) inhibits expression of the human immunodeficiency virus and expression of the interleukin-2 receptor alpha chain.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; NF-kappa B; Phytohemagglutinins; Promoter Regions, Genetic; Protein Binding; Pyrrolidonecarboxylic Acid; Receptors, Interleukin-2; T-Lymphocytes; Thiazoles; Thiazolidines; Virus Replication | 1995 |
Ac-[3- and 4-alkylthioproline31]-CCK4 analogs: synthesis and implications for the CCK-B receptor-bound conformation.
Topics: Amino Acid Sequence; Animals; Cholecystokinin; Humans; Male; Models, Molecular; Molecular Sequence Data; Proline; Protein Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1995 |
Relationship between glutathione concentration and metabolism of the pyrrolizidine alkaloid, monocrotaline, in the isolated, perfused liver.
Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Bile; Buthionine Sulfoximine; Ethylene Chlorohydrin; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Monocrotaline; Perfusion; Pyrroles; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1995 |
Inhibition of IL-1 induced articular inflammation of rats by 4-aminothiazolidines, LY 221068 and LY 269415.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Hindlimb; Humans; Inflammation; Injections, Intra-Articular; Interleukin-1; Rats; Rats, Inbred Lew; Recombinant Proteins; Thiazoles; Thiazolidines | 1994 |
Effect of the platelet activating factor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride on endotoxin-induced hypotension and hematological parameters in rats.
Topics: Animals; Blood Coagulation; Blood Pressure; Dose-Response Relationship, Drug; Endotoxins; Fibrin Fibrinogen Degradation Products; In Vitro Techniques; Iodine Radioisotopes; Male; Platelet Activating Factor; Platelet Count; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1994 |
General toxicology of the new antitussive moguisteine.
Topics: Animals; Antitussive Agents; Carcinogens; Dogs; Female; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mutagens; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1994 |
Reproductive toxicology of the new antitussive moguisteine.
Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Embryo, Mammalian; Female; Fertility; Growth; Labor, Obstetric; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Teratogens; Thiazoles; Thiazolidines; Weight Gain | 1994 |
N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoate.
Topics: Animals; Antitussive Agents; Drug Design; Guinea Pigs; Male; Rats; Thiazoles; Thiazolidines | 1995 |
Pidotimod. A new biological response modifier. Introduction.
Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Humans; Immunologic Factors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Synthesis and preliminary pharmacological evaluation of pidotimod, its enantiomer, diastereomers and carboxamido derivatives.
Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Immunologic Factors; Macrophages; Male; Mice; Mice, Inbred Strains; Prednisolone; Pyrrolidonecarboxylic Acid; Stereoisomerism; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines | 1994 |
Analytical and chemical profile of pidotimod.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Immunologic Factors; Isomerism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Weight; Pyrrolidonecarboxylic Acid; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermogravimetry; Thiazoles; Thiazolidines | 1994 |
Experimental immunological screening tests on pidotimod.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; B-Lymphocytes; Chemotaxis, Leukocyte; Dinitrochlorobenzene; Graft vs Host Reaction; Hypersensitivity, Delayed; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mononuclear Phagocyte System; Organ Size; Pyrrolidonecarboxylic Acid; Sheep; Spleen; T-Lymphocytes; Thiazoles; Thiazolidines; Thymus Gland | 1994 |
Protective effects of pidotimod against experimental bacterial infections in mice.
Topics: Adjuvants, Immunologic; Animals; Anti-Bacterial Agents; Cyclophosphamide; Enterobacteriaceae Infections; Immunosuppression Therapy; Lactams; Male; Mice; Mice, Inbred Strains; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1994 |
Immunomodulating activity of pidotimod.
Topics: Adjuvants, Immunologic; Animals; Apoptosis; Calcimycin; Cell Division; DNA; Female; Flow Cytometry; Killer Cells, Natural; Male; Mice; Mice, Inbred C3H; Mitogens; Protein-Tyrosine Kinases; Pyrrolidonecarboxylic Acid; Spleen; T-Lymphocytes; Thiazoles; Thiazolidines; Tissue Plasminogen Activator; Tumor Cells, Cultured | 1994 |
Effects of pidotimod on macrophage functions in methylprednisolone-treated mice.
Topics: Adjuvants, Immunologic; Animals; Aspergillus fumigatus; Cell Adhesion; Cell Division; Cytokines; Female; Interferon-gamma; Lipopolysaccharides; Macrophages; Methylprednisolone; Mice; Mice, Inbred Strains; Nitric Oxide; Pyrrolidonecarboxylic Acid; Spores, Fungal; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha | 1994 |
In vivo antiviral effects of pidotimod.
Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cardiovirus Infections; Herpes Simplex; Influenza A virus; Male; Mengovirus; Mice; Orthomyxoviridae Infections; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Virus Diseases | 1994 |
Effects of pidotimod on the immune and the neuroendocrine system in the aging rat.
Topics: Adjuvants, Immunologic; Adrenocorticotropic Hormone; Aging; Animals; Cytokines; Immune System; Immunologic Factors; Interleukin-1; Lymphocytes; Male; Mitogens; Neurosecretory Systems; Pituitary-Adrenal System; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Spleen; Thiazoles; Thiazolidines | 1994 |
General pharmacology of pidotimod and testing for drug interactions.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; Behavior, Animal; Central Nervous System; Diuresis; Dogs; Drug Interactions; Guinea Pigs; Hemodynamics; Immunologic Factors; In Vitro Techniques; Male; Mice; Muscle, Smooth; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Respiration; Thiazoles; Thiazolidines | 1994 |
Toxicological evaluation of pidotimod.
Topics: Animals; Dogs; Female; Fertility; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Teratogens; Thiazoles; Thiazolidines | 1994 |
Genotoxicity testing of pidotimod in vitro and in vivo.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Repair; Erythrocytes; HeLa Cells; Humans; In Vitro Techniques; Mice; Micronucleus Tests; Mutagenicity Tests; Mutagens; Pyrrolidonecarboxylic Acid; Rats; Salmonella typhimurium; Thiazoles; Thiazolidines | 1994 |
Pharmacokinetics of pidotimod in rats and dogs.
Topics: Administration, Oral; Animals; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Half-Life; Immunologic Factors; Injections, Intramuscular; Injections, Intravenous; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Tissue Distribution | 1994 |
Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Glutamate-Cysteine Ligase; Glutathione; Mercuric Chloride; Methionine Sulfoximine; Methylmercury Compounds; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Taurine; Thiazoles; Thiazolidines; Tritium | 1994 |
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
Topics: Animals; Azepines; Binding, Competitive; Calcium; Cell Count; Cell Degranulation; Chemotaxis, Leukocyte; Free Radical Scavengers; Inositol 1,4,5-Trisphosphate; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Standards; Signal Transduction; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines; Triazoles; Vitamin E | 1994 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Moguisteine: a novel peripheral non-narcotic antitussive drug.
Topics: Aerosols; Animals; Antitussive Agents; Binding, Competitive; Capsaicin; Citrates; Citric Acid; Codeine; Cough; Dogs; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Physical Stimulation; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Thiazoles; Thiazolidines | 1994 |
Endothelial cell-associated platelet-activating factor primes neutrophils for enhanced superoxide production and arachidonic acid release during adhesion to but not transmigration across IL-1 beta-treated endothelial monolayers.
Topics: Arachidonic Acid; Azepines; Cell Adhesion; Cell Movement; Cell Polarity; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-1; Neutrophil Activation; Neutrophils; Piperazines; Platelet Activating Factor; Superoxides; Thiazoles; Thiazolidines; Triazoles | 1994 |
Formation of the L-cysteine-glyoxylate adduct is the mechanism by which L-cysteine decreases oxalate production from glycollate in rat hepatocytes.
Topics: Animals; Carbon Dioxide; Cysteine; Glycolates; Glyoxylates; Liver; Magnetic Resonance Spectroscopy; Male; Oxalates; Rats; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
The efficacy of (L)-2-oxothiazolidine-4-carboxylate (OTC) and (L)-cysteine in reducing urinary oxalate excretion.
Topics: Animals; Calcium Oxalate; Cysteine; Male; Metabolism; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Time Factors | 1994 |
Novel antioxidant therapy for cerebral ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Brain Ischemia; Butylated Hydroxytoluene; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Thiazoles; Thiazolidines | 1994 |
Direct HPLC separation of enantiomers of main moguisteine metabolite: comparison of different stationary phases.
Topics: Antitussive Agents; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Indicators and Reagents; Orosomucoid; Solvents; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Determination of L-2-oxothiazolidine-4-carboxylic acid (Procysteine) in human plasma by high-performance liquid chromatography.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; HIV Infections; Humans; Indicators and Reagents; Injections, Intravenous; Pyrrolidonecarboxylic Acid; Quality Control; Reference Standards; Respiratory Distress Syndrome; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 1994 |
Role of oxygen free radicals in cocaine-induced vascular disruption in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Aorta; Blood Vessels; Cocaine; Cyclic N-Oxides; Female; Fetal Diseases; Fetal Heart; Gestational Age; Hemorrhage; Lipid Peroxidation; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Nervous System; Nervous System Malformations; Neural Tube Defects; Nitrogen Oxides; Pregnancy; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines; Vasodilation; Yolk Sac | 1994 |
Cerulein-induced pancreatic cysteine depletion: prevention does not diminish acute pancreatitis in the mouse.
Topics: Animals; Ceruletide; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Mice; Mice, Inbred Strains; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors | 1994 |
Thiol metabolism and acute pancreatitis: trying to make the pieces fit.
Topics: Acute Disease; Animals; Ceruletide; Cysteine; Glutathione; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1994 |
Assay of moguisteine metabolites in human plasma and urine: conventional and chiral high-performance liquid chromatographic methods.
Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kinetics; Methylene Chloride; Phosphoric Acids; Sensitivity and Specificity; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Catabolism of cysteine, cystine, cysteinesulfinate, and OTC by isolated perfused rat hindquarter.
Topics: Adenine Nucleotides; Animals; Cysteine; Cystine; Hindlimb; In Vitro Techniques; Lactates; Male; Muscles; Neurotransmitter Agents; Perfusion; Phosphocreatine; Pyrrolidonecarboxylic Acid; Pyruvates; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sulfates; Sulfur Radioisotopes; Taurine; Thiazoles; Thiazolidines | 1993 |
Enhancement of viability of human peritoneal mesothelial cells with glutathione precursor: L-2-oxothiazolidine-4-carboxylate.
Topics: Amino Acids; Cell Division; Cell Survival; Cells, Cultured; Epithelial Cells; Epithelium; Free Radicals; Glutathione; Humans; L-Lactate Dehydrogenase; Peritoneum; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thymidine | 1993 |
Automated column-switching high-performance liquid chromatography for the determination of 2-thiothiazolidine-4-carboxylic acid in urine.
Topics: Acetonitriles; Anions; Autoanalysis; Carbon Disulfide; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Formates; Humans; Occupational Exposure; Thiazoles; Thiazolidines | 1993 |
4-Thiazolidinones, potent antioxidants, as antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Rats; Thiazoles; Thiazolidines | 1993 |
Regulation of hepatocyte glutathione by amino acid precursors and cAMP in protein-energy malnourished rats.
Topics: Amino Acids; Animals; Cells, Cultured; Cyclic AMP; Cysteine; Glutathione; Homeostasis; Liver; Male; Methionine; Oxygen; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1994 |
The utilization of N-acetylcysteine and 2-oxothiazolidine-4-carboxylate by rat hepatocytes is limited by their rate of uptake and conversion to cysteine.
Topics: Acetylcysteine; Animals; Cells, Cultured; Culture Media; Cysteine; Glutathione; Liver; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Selenium Radioisotopes; Thiazoles; Thiazolidines | 1994 |
Use of a new mathematical model in fitting survivorship curves of Drosophila treated with the antioxidant thiazolidine carboxylic acid.
Topics: Aging; Animals; Antioxidants; Dose-Response Relationship, Drug; Drosophila melanogaster; Longevity; Models, Biological; Stochastic Processes; Survival Analysis; Thiazoles; Thiazolidines | 1993 |
Mechanism of methylmercury efflux from cultured astrocytes.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1994 |
Purification and some properties of a novel racemase, which racemizes 2-oxothiazolidine-4-carboxylic acid and 5-oxoproline, from Flectobacillus sp. strain B-1.
Topics: Bacillus; Hydrogen-Ion Concentration; Kinetics; Pyrrolidonecarboxylic Acid; Racemases and Epimerases; Substrate Specificity; Temperature; Thiazoles; Thiazolidines | 1994 |
Thiaproline reduces glomerular basement membrane thickness and collagen accumulation in the db/db mouse.
Topics: Animals; Antioxidants; Basement Membrane; Blood Glucose; Collagen; Diabetic Nephropathies; Disease Models, Animal; Female; Fructosamine; Hexosamines; Kidney; Kidney Glomerulus; Mice; Mice, Inbred Strains; Organ Size; Solubility; Thiazoles; Thiazolidines | 1994 |
Biological effects of the new platelet-activating factor receptor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride.
Topics: Anaphylaxis; Animals; Blood Platelets; Blood Pressure; Endotoxins; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Effects of glutathione precursors on human immunodeficiency virus replication.
Topics: Acetylcysteine; beta-Galactosidase; Cell Line; Colorimetry; Gene Expression Regulation, Viral; Glutathione; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; HIV Long Terminal Repeat; Homocysteine; Humans; Interleukin-6; Prodrugs; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Virus Replication | 1994 |
Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels.
Topics: Acetylcysteine; Animals; Arteries; Drug Tolerance; Female; Nitrates; Nitroglycerin; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Reference Values; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Veins | 1994 |
A new HPLC method for pidotimod plasma levels determination.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Immunologic Factors; Male; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1993 |
Partial prevention of glutathione depletion in rats following acute intoxication with diethylmaleate.
Topics: Animals; Brain; Cysteine; Glutathione; Heart; Kidney; Liver; Male; Maleates; Myocardium; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1993 |
The effect of 2-substituted thiazolidine-4(R)-carboxylic acids on non-protein sulphydryl levels and sulphurtransferase activities in mouse liver and brain.
Topics: Animals; Brain; Female; Liver; Mice; Proline; Sulfhydryl Compounds; Sulfurtransferases; Thiazoles; Thiazolidines; Thiosulfate Sulfurtransferase | 1993 |
Protective effect of RibCys following high-dose irradiation of the rectosigmoid.
Topics: Anastomosis, Surgical; Animals; Cobalt Radioisotopes; Colon, Sigmoid; Cysteine; Male; Oxygen Consumption; Pressure; Prodrugs; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Radioisotope Teletherapy; Rectum; Rupture; Swine; Thiazoles; Thiazolidines | 1993 |
Stimulation by the antioxidant thioproline of the lymphocyte functions of old mice.
Topics: Aging; Amino Acid Sequence; Animals; Antioxidants; Cell Division; Female; Lymphocytes; Mice; Molecular Sequence Data; Thiazoles; Thiazolidines | 1993 |
Toxicity evaluations of L-cysteine and Procysteine, a cysteine prodrug, given once intravenously to neonatal rats.
Topics: Animals; Animals, Newborn; Body Weight; Cysteine; Injections, Intravenous; Organ Size; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1993 |
Biological monitoring of workers occupationally exposed to carbon disulphide in a rayon plant in Brazil: validity of 2-thiothiazolidine-4-carboxylic acid (TTCA) in urine samples taken in different times, during and after the real exposure period.
Topics: Air Pollutants, Occupational; Brazil; Carbon Disulfide; Cellulose; Environmental Monitoring; Humans; Occupational Exposure; Textile Industry; Thiazoles; Thiazolidines; Time Factors | 1993 |
Platelet-activating factor and the vascular effects of zymosan in rats.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Female; Hematocrit; Hemodynamics; Iodine Radioisotopes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Triazoles; Zymosan | 1993 |
Clinical and experimental studies on the role of platelet-activating factor (PAF) in the pathogenesis of septic DIC.
Topics: Aged; Animals; Blood Pressure; Disseminated Intravascular Coagulation; Female; Fibrinolysis; Guanidines; Humans; Male; Middle Aged; Neoplasms; Platelet Activating Factor; Platelet Count; Postoperative Complications; Rabbits; Serine Proteinase Inhibitors; Shock, Septic; Thiazoles; Thiazolidines | 1993 |
Captan metabolism in humans yields two biomarkers, tetrahydrophthalimide (THPI) and thiazolidine-2-thione-4-carboxylic acid (TTCA) in urine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Biomarkers; Biotransformation; Captan; Dose-Response Relationship, Drug; Humans; Male; Phthalimides; Thiazoles; Thiazolidines | 1993 |
Pharmacokinetic study of a tripeptide HIV-1 protease inhibitor, KNI-174, in rats after intravenous and intraduodenal administrations.
Topics: Animals; Asparagine; Biological Availability; Chromatography, High Pressure Liquid; Duodenum; Half-Life; HIV Protease Inhibitors; HIV-1; Injections, Intravenous; Intubation, Gastrointestinal; Male; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1993 |
Direct enantiomeric separation of platelet-activating factor receptor antagonist SM-10661 by ligand-exchange high-performance liquid chromatography with a copper (II) N,S-dioctyl-D-penicillamine complex.
Topics: Cations; Chromatography, High Pressure Liquid; Copper; Isomerism; Penicillamine; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1995 |
Toxicity and growth-promoting potential of spermine when fed to chicks.
Topics: Adenosylmethionine Decarboxylase; Animal Feed; Animals; Chickens; Cysteine; Diet; Dose-Response Relationship, Drug; Eating; Glutathione; Kidney; Liver; Male; Muscle, Skeletal; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Pyrrolidonecarboxylic Acid; Spermine; Thiazoles; Thiazolidines | 1995 |
[Pidotimod causes apoptotic cell death and inhibits the proliferative activity of YAC-1 tumor cells in vitro].
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Calcium; Cell Division; DNA, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase; Lymphoma, T-Cell; Mice; Mice, Inbred A; Mitosis; Neoplasm Proteins; Neoplastic Stem Cells; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidonecarboxylic Acid; T-Lymphocytes; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1993 |
[Potentiation of the resistance to viral and bacterial infections after pidotimod administration in mice].
Topics: Adjuvants, Immunologic; Animals; Bacterial Infections; Coxsackievirus Infections; Enterovirus B, Human; Female; Immunity, Innate; Influenza A virus; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Pyrrolidonecarboxylic Acid; Streptococcal Infections; Streptococcus agalactiae; Thiazoles; Thiazolidines; Virus Diseases | 1993 |
[Stimulation of B-cell immunity in the nude mice by pidotimod: immunohistochemical stucy of various lymphoid organs].
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; B-Lymphocytes; Cell Differentiation; Immunoenzyme Techniques; Immunoglobulins; Immunologic Deficiency Syndromes; Intestinal Mucosa; Lung; Lymph Nodes; Lymphocyte Activation; Lymphoid Tissue; Mice; Mice, Nude; Pyrrolidonecarboxylic Acid; Spleen; Thiazoles; Thiazolidines | 1993 |
[Effect of pidotimod on phagocytosis and intracellular killing of Staphylococcus aureus by human circulating polymorphonuclear neutrophils and alveolar macrophages].
Topics: Adjuvants, Immunologic; Adolescent; Adult; Coloring Agents; Cytotoxicity, Immunologic; Female; Fluorescent Dyes; Humans; Hydrogen Peroxide; Indoles; Macrophage Activation; Macrophages, Alveolar; Male; Microscopy, Fluorescence; Neutrophils; Phagocytosis; Pyrrolidonecarboxylic Acid; Respiratory Burst; Staphylococcus aureus; Thiazoles; Thiazolidines | 1993 |
[Effect of pidotimod on the function of the human immune system: in vitro and ex vivo study].
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Antibody Formation; Chemotaxis, Leukocyte; Humans; Immune System; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-6; Lymphocyte Activation; Lymphocyte Subsets; Mitogens; Muromonab-CD3; Neutrophils; Phagocytosis; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1993 |
[Levels of interleukin-2 )IL-2 and tumor necrosis factor alpha (TNF-alpha) mRNA in aged rat spleen under physiological conditions and in septic shock: possible role of pidotimod in gene expression modulation].
Topics: Adjuvants, Immunologic; Aging; Animals; Escherichia coli Infections; Gene Expression Regulation; Interleukin-2; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shock, Septic; Spleen; Stimulation, Chemical; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha | 1993 |
(+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Thiazoles; Thiazolidines | 1996 |
Increased gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity.
Topics: Animals; Antioxidants; Benzoquinones; Cell Line; Drug Resistance; Epithelium; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Hydroquinones; Lung; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1996 |
Selective glutathione repletion with oral oxothiazolidine carboxylate (OTZ) in the radiated tumor-bearing rat.
Topics: Administration, Oral; Animals; Glutathione; Kidney; Male; Oxidation-Reduction; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines; Tissue Distribution | 1996 |
Effects of latrunculin A on immunological phagocytosis and macrophage spreading-associated changes in the F-actin/G-actin content of the cells.
Topics: Actins; Animals; Antigen-Antibody Complex; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Size; Cytoskeleton; Erythrocytes; Macrophage Activation; Macrophages; Marine Toxins; Mice; Phagocytosis; Porifera; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1996 |
Treatment of peripheral leukopenia after cadaveric kidney transplantation.
Topics: Adenine; Adult; Azathioprine; Blood Transfusion; Cadaver; Drug Therapy, Combination; Female; Glyceryl Ethers; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukocyte Transfusion; Leukopenia; Male; Middle Aged; Postoperative Complications; Thiazoles; Thiazolidines; Tissue Donors | 1996 |
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3 | 1996 |
L-2-Oxothiazolidine-4-carboxylate and N-acetylcysteine as precursors of intracellular glutathione in human peritoneal mesothelial cells.
Topics: Acetylcysteine; Cells, Cultured; Epithelial Cells; Epithelium; Free Radical Scavengers; Free Radicals; Glutathione; Humans; Peritoneum; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1996 |
S-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)-thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast.
Topics: Animals; Hydrogen-Ion Concentration; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Platelet Activating Factor; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 1995 |
Antitussive activity of moguisteine enantiomers in guinea-pigs and rats.
Topics: Administration, Oral; Aerosols; Animals; Antacids; Antitussive Agents; Capsaicin; Citric Acid; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Injections, Intraperitoneal; Lethal Dose 50; Male; Rats; Rats, Sprague-Dawley; Species Specificity; Stereoisomerism; Thiazoles; Thiazolidines | 1996 |
Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antitussive Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inflammation; Male; Regression Analysis; Respiratory System; Smoke; Thiazoles; Thiazolidines | 1996 |
Microfilament-disrupting agent latrunculin A induces and increased number of fenestrae in rat liver sinusoidal endothelial cells: comparison with cytochalasin B.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytochalasin B; Endothelium, Vascular; Liver Circulation; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Porifera; Rats; Thiazoles; Thiazolidines | 1996 |
A novel platelet activating factor antagonist, SM-12502, attenuates endotoxin-induced disseminated intravascular coagulation and acute pulmonary vascular injury by inhibiting TNF production in rats.
Topics: Animals; Blood Coagulation; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Female; Humans; Infant, Newborn; Platelet Activating Factor; Pulmonary Artery; Rats; Rats, Wistar; Respiratory Distress Syndrome, Newborn; Thiazoles; Thiazolidines | 1996 |
Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding, Competitive; Cell Line; CHO Cells; Cricetinae; Humans; Male; Molecular Structure; Motor Activity; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Serotonin; Spiperone; Spiro Compounds; Stereotyped Behavior; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1996 |
Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells.
Topics: Acetylcysteine; Antioxidants; Arthritis, Rheumatoid; Cells, Cultured; Chemokine CCL2; Collagenases; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Interleukin-8; NF-kappa B; Pyrrolidonecarboxylic Acid; RNA, Messenger; Synovial Membrane; Thiazoles; Thiazolidines; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1996 |
Sensitivity of Escherichia coli to proline analogues during osmotic stress and anaerobiosis.
Topics: Anaerobiosis; Azetidinecarboxylic Acid; Betaine; Drug Resistance, Microbial; Drug Stability; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Osmotic Pressure; Proline; Thiazoles; Thiazolidines; Urinary Tract Infections | 1996 |
Metabolism of an atypical antipsychotic agent, 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2, 5,5-trimethyl-4-thiazolidinone (HP236).
Topics: Animals; Antipsychotic Agents; Biotransformation; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1996 |
Actions of CP-060S on veratridine-induced Ca2+ overload in cardiomyocytes and mechanical activities in vascular strips.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Drug Interactions; Heart; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasodilator Agents; Veratridine | 1996 |
Antitussive effect of moguisteine on the enhanced coughing associated with enalapril in guinea-pig.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Enalapril; Guinea Pigs; Male; Thiazoles; Thiazolidines | 1996 |
Oral L-2-oxo-4-thiazolidine reduces bacterial translocation after radiation in the Fischer rat.
Topics: Administration, Oral; Animals; Bacteria; Bacterial Translocation; Body Weight; Buthionine Sulfoximine; Cells, Cultured; Eating; Glutathione; Jejunum; Liver; Lymph Nodes; Mesentery; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines | 1996 |
Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502.
Topics: Aluminum; Basophils; Calcimycin; Calcium; Depression, Chemical; Gene Expression Regulation; GTP-Binding Proteins; Humans; Interleukin-8; Ionophores; Leukocytes, Mononuclear; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines | 1996 |
Effect of the PAF-receptor antagonist SM-12502 on human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aluminum; Arachidonate 12-Lipoxygenase; Calcimycin; Calcium; Fatty Acids, Unsaturated; Gene Expression Regulation; GTP-Binding Proteins; Humans; Ionophores; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines; Thrombin | 1996 |
Modulation of fatty acid oxidation alters contact hypersensitivity to urushiols: role of aliphatic chain beta-oxidation in processing and activation of urushiols.
Topics: Allergens; Animals; Carnitine O-Palmitoyltransferase; Catechols; Clofibrate; Dermatitis, Contact; Epoxy Compounds; Fatty Acids; Hypoglycemic Agents; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Plant Extracts; Plants, Toxic; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors | 1997 |
Synthesis of 2-thiothiazolidine-4-carboxylic acid and its chromatography in rat and human urine.
Topics: Animals; Biomarkers; Carbon Disulfide; Chromatography, High Pressure Liquid; Humans; Male; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Thiazoles; Thiazolidines | 1996 |
Comparative toxicology of two enantiomers of the peripherally acting non-narcotic antitussive drug moguisteine.
Topics: Administration, Oral; Animals; Antitussive Agents; Body Weight; Dogs; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Organ Size; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles; Thiazolidines | 1996 |
Study of non-covalent enzyme-inhibitor complexes of aldose reductase by electrospray mass spectrometry.
Topics: Acetates; Aldehyde Reductase; Animals; Apoenzymes; Enzyme Inhibitors; Furans; Imidazoles; Imidazolidines; Lens, Crystalline; Mass Spectrometry; NADP; Naphthalenes; Rhodanine; Swine; Thiazoles; Thiazolidines | 1997 |
Effects of F-actin stabilization or disassembly on epithelial Cl- secretion and Na-K-2Cl cotransport.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Chlorides; Cytochalasin D; Cytoskeleton; Depsipeptides; Drug Stability; Humans; Intestinal Mucosa; Intracellular Membranes; Peptides, Cyclic; Sodium-Potassium-Chloride Symporters; Thiazoles; Thiazolidines | 1997 |
Role of plasma insulin concentration in regulating glucose and lipid metabolism in lean and obese Zucker rats.
Topics: Administration, Oral; Animals; Blood Glucose; Cholesterol; Cholesterol, HDL; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred Strains; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidines; Time Factors; Triglycerides | 1997 |
The in vitro effect of Pidotimod on some immune functions in cancer patients.
Topics: Adjuvants, Immunologic; Female; Humans; Immunity, Cellular; Immunologic Factors; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
L-oxothiazolidine 4-carboxylate pretreatment of isolated human peripheral blood lymphocytes reduces sulfur mustard cytotoxicity.
Topics: Antidotes; Cell Separation; Cell Survival; Drug Administration Schedule; Free Radical Scavengers; Glutathione; Humans; Lymphocytes; Mustard Gas; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Toxicity Tests | 1997 |
N-acetyl-cysteine and L-2-oxothiazolidine-4-carboxylic acid enhance contact-dependent growth of HIV in resting peripheral blood mononuclear cells (PBMC) in vitro and increase recovery of HIV from human-PBMC SCID mice.
Topics: Acetylcysteine; Animals; Anti-HIV Agents; CD2 Antigens; Cell Division; Cells, Cultured; Coculture Techniques; Down-Regulation; Female; HIV-1; Humans; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Male; Mice; Mice, SCID; Monocytes; Peritoneal Cavity; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Virus Replication; Zidovudine | 1997 |
Protective effects of L-2-oxothiazolidine-4-carboxylate treatment on cyclophosphamide-induced cystitis in rats.
Topics: Animals; Cyclophosphamide; Cystitis; Male; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1997 |
High rates of actin filament turnover in budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Polarity; Endocytosis; Fungal Proteins; Resting Phase, Cell Cycle; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 1997 |
Effect of SM-12502 on disseminated intravascular coagulation (DIC) in tumor-bearing rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disseminated Intravascular Coagulation; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured | 1996 |
Beneficial effects of L-2-oxothiazolidine-4-carboxylate on cerulein pancreatitis in mice.
Topics: Amylases; Animals; Ceruletide; Disulfides; Female; Glutathione; Glutathione Disulfide; Mice; Pancreas; Pancreatitis; Pyrrolidonecarboxylic Acid; Receptors, Cholecystokinin; Reference Values; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1997 |
L-2-oxothiazolidine-4-carboxylic acid inhibits human immunodeficiency virus type 1 replication in mononuclear phagocytes and lymphocytes.
Topics: Adult; Anti-HIV Agents; Cells, Cultured; Female; Fetal Blood; HIV Infections; HIV-1; Humans; In Vitro Techniques; Infant, Newborn; Lymphocytes; Phagocytes; Pregnancy; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Virus Replication | 1997 |
Redox state changes in density-dependent regulation of proliferation.
Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Division; Cell Line; Contact Inhibition; Fibroblasts; Fibrosarcoma; Glutathione; Humans; Male; Neoplasm Proteins; Oxidation-Reduction; Protein Binding; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transcription Factors; Tumor Cells, Cultured | 1997 |
Actions of moguisteine on cough and pulmonary rapidly adapting receptor activity in the guinea pig.
Topics: Aerosols; Animals; Antitussive Agents; Binding Sites; Capsaicin; Cough; Dimethyl Sulfoxide; Female; Guinea Pigs; Lung; Male; Mechanoreceptors; Receptors, Cell Surface; Thiazoles; Thiazolidines | 1997 |
Autoregulation of actin synthesis responds to monomeric actin levels.
Topics: 3T3 Cells; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytotoxins; Dimerization; Marine Toxins; Mice; Protein Conformation; RNA; Thiazoles; Thiazolidines | 1997 |
Neurotoxicity of long-term low-level exposure to carbon disulphide: results of questionnaire, clinical neurological examination and neuropsychological testing.
Topics: Adult; Air Pollutants, Occupational; Carbon Disulfide; Cohort Studies; Cross-Sectional Studies; Humans; Male; Middle Aged; Nervous System Diseases; Neurologic Examination; Neuropsychological Tests; Occupational Diseases; Occupational Exposure; Surveys and Questionnaires; Thiazoles; Thiazolidines | 1997 |
A novel synthetic inhibitor of endopeptidase-24.15.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Kinetics; Male; Metalloendopeptidases; Molecular Structure; Neprilysin; Oligopeptides; Phenylalanine; Protease Inhibitors; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1996 |
Cofilin promotes rapid actin filament turnover in vivo.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Endocytosis; Microfilament Proteins; Mutation; Nerve Tissue Proteins; Saccharomyces cerevisiae; Temperature; Thiazoles; Thiazolidines | 1997 |
Effects of CP-060S on membrane channels in vascular smooth muscle cells from guinea pig.
Topics: Animals; Calcium Channels; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Sodium Channels; Thiazoles; Thiazolidines | 1997 |
Activity and distribution of the cysteine prodrug activating enzyme, 5-oxo-L-prolinase, in human normal and tumor tissues.
Topics: Cysteine; Humans; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Latrunculin A is a potent inducer of aggregation of polymorphonuclear leukocytes.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Aggregation; Kinetics; Magnesium; Marine Toxins; Neutrophils; Porifera; Rabbits; Thiazoles; Thiazolidines | 1997 |
The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Clathrin; Deoxyribonuclease I; Endocytosis; Humans; Receptors, Transferrin; Thiazoles; Thiazolidines; Thymosin | 1997 |
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Thiols and selenium: protective effect on human skin fibroblasts exposed to UVA radiation.
Topics: Acetylcysteine; Antioxidants; Cell Survival; Cells, Cultured; Cysteine; Dose-Response Relationship, Radiation; Female; Fibroblasts; Glutathione; Humans; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Skin; Sodium Selenite; Surgery, Plastic; Thiazoles; Thiazolidines; Thiophenes; Ultraviolet Rays | 1997 |
2-Methyl-thiazolidine-2,4-dicarboxylic acid as prodrug of L-cysteine. Protection against paracetamol hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Oxidative Stress; Prodrugs; Thiazoles; Thiazolidines | 1997 |
Cloning and expression of the pea gene encoding SBP65, a seed-specific biotinylated protein.
Topics: Abscisic Acid; Amanitins; Base Sequence; Biotin; Biotinylation; Caproates; Cloning, Molecular; Gene Expression Regulation, Plant; Genes, Plant; Germination; Models, Chemical; Molecular Sequence Data; Osmotic Pressure; Pisum sativum; Plant Proteins; Polyethylene Glycols; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; RNA, Plant; Seeds; Thiazoles; Thiazolidines | 1997 |
2-(3-Pyridyl)thiazolidine-4-carboxamides. 1. Novel orally active antagonists of platelet-activating factor (PAF).
Topics: Animals; Capillary Permeability; Guinea Pigs; Hematocrit; Humans; Mice; Piperazines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Rats; Rats, Wistar; Species Specificity; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1997 |
Alterations of intraperitoneal inflammation by the addition of L-2-oxothiazolidine-carboxylate.
Topics: Albumins; Animals; Creatinine; Dialysis Solutions; Glutathione; Leukocytes; Male; Nitrites; Peritoneal Dialysis; Peritoneum; Peritonitis; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1997 |
High-performance liquid chromatographic assay for CI-1004, a dual-inhibitor antiinflammatory agent, in rat, rabbit, dog, monkey and human plasma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Dogs; Haplorhini; Humans; Rabbits; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Thiazoles; Thiazolidines | 1997 |
The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Drosophila; Drosophila Proteins; Juvenile Hormones; Myristic Acid; Thiazoles; Thiazolidines | 1997 |
In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biotransformation; Cytochrome P-450 Enzyme System; Humans; Inactivation, Metabolic; Isoenzymes; Kinetics; Microsomes, Liver; Phenols; Thiazoles; Thiazolidines | 1997 |
Biological monitoring of workers exposed to carbon disulfide.
Topics: Air Pollutants, Occupational; Biomarkers; Carbon Disulfide; Cellulose; Humans; Lod Score; Male; Monitoring, Physiologic; Occupational Exposure; Respiratory Protective Devices; Rubber; Textile Industry; Thiazoles; Thiazolidines | 1998 |
Macrophage glutathione content and glutathione peroxidase activity are inversely related to cell-mediated oxidation of LDL: in vitro and in vivo studies.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Buthionine Sulfoximine; Cell Line; Glutathione; Glutathione Peroxidase; Lipoproteins, LDL; Macrophages; Macrophages, Peritoneal; Mice; Mice, Transgenic; Oxidation-Reduction; Peroxides; Pyrrolidonecarboxylic Acid; Selenium; Superoxides; Thiazoles; Thiazolidines | 1998 |
Residue-specific bioincorporation of non-natural, biologically active amino acids into proteins as possible drug carriers: structure and stability of the per-thiaproline mutant of annexin V.
Topics: Annexin A5; Drug Carriers; Escherichia coli; Humans; Mutation; Recombinant Proteins; Thiazoles; Thiazolidines | 1998 |
Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine.
Topics: Animals; Astrocytes; Brain; Brain Chemistry; Cell Survival; Cells, Cultured; Cystathionine; Cysteine; Cystine; gamma-Glutamyltransferase; Glutathione; Methionine; Nerve Tissue Proteins; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1998 |
Insulin sensitizer YM268 ameliorates insulin resistance by normalizing the decreased content of GLUT4 in adipose tissue of obese Zucker rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Zucker; Thiazoles; Thiazolidines | 1997 |
Myosin cooperates with microtubule motors during organelle transport in melanophores.
Topics: Actin Cytoskeleton; Actins; Animals; Biological Transport, Active; Bridged Bicyclo Compounds, Heterocyclic; Cyclic AMP; Cytochalasin B; Cytoskeleton; Melanocyte-Stimulating Hormones; Melanocytes; Melanophores; Microtubules; Myosins; Thiazoles; Thiazolidines; Xenopus laevis | 1998 |
Functional coordination of microtubule-based and actin-based motility in melanophores.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Animals; Biological Transport, Active; Bridged Bicyclo Compounds, Heterocyclic; Cypriniformes; Cytochalasin D; Melanocytes; Melanophores; Microtubules; Myosins; Nocodazole; Thiazoles; Thiazolidines | 1998 |
Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.
Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Neutrophils; P-Selectin; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles | 1998 |
A novel protein complex promoting formation of functional alpha- and gamma-tubulin.
Topics: Actins; Animals; Benomyl; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Conserved Sequence; Cytoplasm; Cytoskeletal Proteins; DNA-Binding Proteins; Fungal Proteins; Gene Deletion; Genes, Fungal; Genes, Lethal; Humans; Macromolecular Substances; Mice; Microtubule-Associated Proteins; Microtubules; Molecular Chaperones; Nuclear Proteins; Osmotic Pressure; Phylogeny; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines; Transformation, Genetic; Tubulin | 1998 |
Effect of PAF receptor antagonists on adrenocortical secretion induced by ACTH in normal and athymic nude mice.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Colforsin; Corticosterone; Male; Mice; Mice, Inbred ICR; Mice, Nude; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1998 |
F-actin distribution and function during sexual differentiation in Schizosaccharomyces pombe.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Polarity; Cytoskeleton; Fungal Proteins; Meiosis; Nitrogen; Pheromones; Profilins; Reproduction; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines | 1998 |
Carbon disulfide neurotoxicity in rats: II. Toxicokinetics.
Topics: Administration, Inhalation; Animals; Carbon Disulfide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intravenous; Male; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines | 1998 |
Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.
Topics: Actinin; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Cytoskeleton; Dendrites; Detergents; Disks Large Homolog 4 Protein; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Pyramidal Cells; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Solubility; Synapses; Thiazoles; Thiazolidines | 1998 |
CP-060S, a novel cardioprotective drug, limits myocardial infarct size in anesthetized dogs.
Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Dogs; Hemodynamics; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Thiazoles; Thiazolidines | 1998 |
Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: a potential new target for biochemical modulation of glutathione.
Topics: Animals; Female; Glutathione; Humans; Immunohistochemistry; Neoplasms; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines | 1998 |
Role of glutathione in protection against noise-induced hearing loss.
Topics: Animals; Antioxidants; Auditory Threshold; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cochlea; Cysteine; Evoked Potentials, Auditory, Brain Stem; Female; Glutathione; Guinea Pigs; Hearing Loss, Noise-Induced; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Disruption of the actin cytoskeleton abolishes high affinity 3H-glibenclamide binding in rat aortic rings.
Topics: Actins; Adenosine Triphosphate; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Cytoskeleton; Glyburide; Guanidines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Phalloidine; Potassium Channel Blockers; Potassium Channels; Pyridines; Rats; Thiazoles; Thiazolidines; Vasodilator Agents | 1998 |
Selective elevation of glutathione levels in target tissues with L-2-oxothiazolidine-4-carboxylate (OTC) protects against hyperoxia-induced lung damage in protein-energy malnourished rats: implications for a new treatment strategy.
Topics: Animals; Dietary Proteins; Glutathione; Hyperoxia; Lung; Male; Protein-Energy Malnutrition; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1998 |
CP-060S interacts with three principal binding sites on the L-type Ca2+ channel.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Heart; In Vitro Techniques; Kinetics; Male; Myocardium; Radioligand Assay; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1998 |
Action of moguisteine on the activity of tracheobronchial rapidly adapting receptors in the dog.
Topics: Adaptation, Physiological; Animals; Antitussive Agents; Bronchi; Dogs; Female; Male; Pulmonary Stretch Receptors; Thiazoles; Thiazolidines; Time Factors; Trachea | 1998 |
Biological monitoring of workers exposed to carbon disulfide (CS2) in a viscose rayon fibers factory.
Topics: Adult; Carbon Disulfide; Environmental Monitoring; Humans; Male; Middle Aged; Occupational Exposure; Textiles; Thiazoles; Thiazolidines | 1998 |
Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Actins; Adipocytes; Androstadienes; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Enzyme Activation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Mice; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Thiazoles; Thiazolidines; Wortmannin | 1998 |
Antioxidant action via p53-mediated apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Dimercaprol; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E | 1998 |
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium | 1998 |
The protective effects of CP-060S on ischaemia- and reperfusion- induced arrhythmias in anaesthetized rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzothiazoles; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion; Piperidines; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1998 |
2-Methyl-thiazolidine-2,4-dicarboxylic acid protects against paracetamol induced toxicity in human liver derived HepG2 cells.
Topics: Acetaminophen; Antidotes; Benzoquinones; Cell Line; Cysteine; Glutathione; Humans; Imines; Liver; Malondialdehyde; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Thiazoles; Thiazolidines | 1997 |
The effect of (L)-cysteine and (L)-2-oxothiazolidine-4-carboxylic acid (OTZ) on urinary oxalate excretion: studies using a hyperoxaluric rat model.
Topics: Animals; Cysteine; Disease Models, Animal; Male; Oxalates; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Urinary Calculi | 1998 |
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay.
Topics: Androstadienes; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Fractionation; Cell Line; Colorimetry; Cytochalasin D; Deoxyglucose; Enzyme Inhibitors; Glucose Transporter Type 4; Immunoenzyme Techniques; Insulin; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nucleic Acid Synthesis Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Wortmannin | 1998 |
Spectrophotometric investigation of the formed chelate between timonacic and palladium(II) and its analytical applications.
Topics: Antineoplastic Agents; Chelating Agents; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Palladium; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets; Thiazoles; Thiazolidines | 1998 |
Thiazolidinyl- and perhydrothiazinylphosphamidesters: toxicity and preliminary antitumour evaluation.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Injections, Intraperitoneal; Leukemia P388; Male; Mast-Cell Sarcoma; Mice; Nitrogen Mustard Compounds; Prodrugs; Protein Binding; Thiazines; Thiazoles; Thiazolidines; Tissue Distribution | 1997 |
Rapid actin-based plasticity in dendritic spines.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Size; Cytochalasin D; Dendrites; Fibroblasts; Green Fluorescent Proteins; Hippocampus; Indicators and Reagents; Luminescent Proteins; Microscopy, Video; Neuronal Plasticity; Neurons; Nucleic Acid Synthesis Inhibitors; Rats; Synapses; Thiazoles; Thiazolidines | 1998 |
Interaction between mitochondria and the actin cytoskeleton in budding yeast requires two integral mitochondrial outer membrane proteins, Mmm1p and Mdm10p.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Fungal Proteins; Membrane Proteins; Mitochondria; Mutagenesis; Potassium Chloride; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 1998 |
Roles of secretion and the cytoskeleton in cell adhesion and polarity establishment in Pelvetia compressa zygotes.
Topics: Actins; Anti-Bacterial Agents; Bodily Secretions; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cyclopentanes; Cytochalasin D; Cytoskeleton; Dinitrobenzenes; Eukaryota; Light; Macrolides; Microscopy, Confocal; Monensin; Sulfanilamides; Thiazoles; Thiazolidines; Zygote | 1998 |
Radial F-actin arrays precede new hypha formation in Saprolegnia: implications for establishing polar growth and regulating tip morphogenesis.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Wall; Marine Toxins; Morphogenesis; Oomycetes; Spores, Fungal; Thiazoles; Thiazolidines | 1998 |
Antitussive effect of moguisteine on allergic coughs in the guinea pig.
Topics: Analgesics, Opioid; Animals; Antitussive Agents; Codeine; Cough; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Male; Thiazoles; Thiazolidines | 1998 |
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).
Topics: Aryl Hydrocarbon Hydroxylases; Base Sequence; Cloning, Molecular; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Gene Deletion; Genomic Library; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Substrate Specificity; Thiazoles; Thiazolidines | 1998 |
Disruption of endothelial microfilaments selectively reduces the transendothelial migration of monocytes.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Coculture Techniques; Colchicine; Culture Media, Conditioned; Cytochalasin B; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Microscopy, Fluorescence; Monocytes; Nocodazole; Paclitaxel; Protein Kinase C; Sulfonamides; Thiazoles; Thiazolidines; Trifluoperazine; Tumor Necrosis Factor-alpha | 1998 |
The yeast V159N actin mutant reveals roles for actin dynamics in vivo.
Topics: Actins; Adenosine Triphosphate; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeletal Proteins; Endocytosis; Fluorescent Antibody Technique; Fluorescent Dyes; Fungal Proteins; Genes, Fungal; Microscopy, Fluorescence; Protein Binding; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 1998 |
Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis.
Topics: Actins; Actomyosin; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Division; Fluorescent Antibody Technique; Fungal Proteins; Microscopy, Video; Molecular Sequence Data; Myosin Heavy Chains; Myosins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Deletion; Thiazoles; Thiazolidines | 1998 |
A morphogenesis checkpoint monitors the actin cytoskeleton in yeast.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cytoskeleton; Morphogenesis; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Thiazoles; Thiazolidines | 1998 |
Protective effects of a PAF receptor antagonist and a neutrophil elastase inhibitor on multiple organ failure induced by cerulein plus lipopolysaccharide in rats.
Topics: Alanine Transaminase; Amylases; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney; Leukocyte Elastase; Lipase; Lipopolysaccharides; Liver; Lung; Male; Multiple Organ Failure; Organ Size; Pancreas; Pancreatitis; Piperazines; Platelet Membrane Glycoproteins; Pyridones; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfonamides; Survival Rate; Thiazoles; Thiazolidines; Time Factors | 1998 |
Sensitization effect of L-2-oxothiazolidine-4-carboxylate on tumor cells to melphalan and the role of 5-oxo-L-prolinase in glutathione modulation in tumor cells.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Synergism; Glutathione; Humans; Melphalan; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1998 |
Use of latrunculin-A, an actin monomer-binding drug.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytoskeleton; Marine Toxins; Mutation; Phalloidine; Porifera; Protein Binding; Rhodamines; Saccharomyces cerevisiae; Schizosaccharomyces; Thiazoles; Thiazolidines | 1998 |
L-2-Oxothiazolidine-4-carboxylic acid prevents endotoxin-induced cardiac dysfunction.
Topics: Analysis of Variance; Animals; Endotoxins; Escherichia coli; Free Radicals; Glutathione; Infusions, Intravenous; Injections, Subcutaneous; Leukocyte Count; Myocardial Contraction; Myocardium; Prodrugs; Pyrrolidonecarboxylic Acid; Rabbits; Reactive Oxygen Species; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left | 1998 |
Actin filaments facilitate insulin activation of the src and collagen homologous/mitogen-activated protein kinase pathway leading to DNA synthesis and c-fos expression.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cells, Cultured; Cytochalasin D; DNA; Enzyme Activation; GRB2 Adaptor Protein; Insulin; Models, Biological; Muscles; Phosphorylation; Protein Binding; Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; ras Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; src-Family Kinases; Thiazoles; Thiazolidines | 1998 |
2-(3-Pyridyl)thiazolidine-4-carboxamide derivatives. II. Structure-activity relationships and active configuration of 2-(3-pyridyl)thiazolidine-4-carboxamides as platelet-activating factor receptor antagonists.
Topics: Animals; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1998 |
Protection by L-2-oxothiazolidine-4-carboxylic acid of hydrogen peroxide-induced CD3zeta and CD16zeta chain down-regulation in human peripheral blood lymphocytes and lymphokine-activated killer cells.
Topics: CD3 Complex; Cytoprotection; Down-Regulation; Humans; Hydrogen Peroxide; Killer Cells, Lymphokine-Activated; Lipopolysaccharides; Lymphocytes; Monocytes; Pyrrolidonecarboxylic Acid; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Receptors, IgG; Signal Transduction; Thiazoles; Thiazolidines | 1998 |
Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 1. 2-(3, 5-di-tert-butyl-4-hydroxyphenyl)-3-(aminopropyl)thiazolidinones.
Topics: Animals; Antioxidants; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Glycine max; Heart; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Lipoxygenase; Male; Myocardium; Phenols; Rabbits; Rats; Thiazoles; Thiazolidines; Veratridine | 1998 |
Pharmacokinetics of 2-oxothiazolidine-4-carboxylate, a cysteine prodrug, and cysteine.
Topics: Adult; Cysteine; Glutathione; Humans; Infusions, Intravenous; Male; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
YM268 increases the glucose uptake, cell differentiation, and mRNA expression of glucose transporter in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Carrier Proteins; Cell Differentiation; Deoxyglucose; Dose-Response Relationship, Drug; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Gene Expression; Genes, Reporter; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Inositol 1,4,5-Trisphosphate; Insulin; Mice; Monocytes; Monosaccharide Transport Proteins; Muscle Proteins; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Pioglitazone; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Triglycerides; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1998 |
AFM imaging and elasticity measurements on living rat liver macrophages.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin B; Elasticity; Kupffer Cells; Liver; Microscopy, Atomic Force; Rats; Thiazoles; Thiazolidines | 1997 |
Enhancement of leukocyte functions in aged mice supplemented with the antioxidant thioproline.
Topics: Aging; Animals; Antioxidants; Cell Movement; Chemotaxis; Corticosterone; Cytotoxicity, Immunologic; Dietary Supplements; Female; Killer Cells, Natural; Leukocytes; Mice; Thiazoles; Thiazolidines | 1998 |
F-actin marks the rhizoid pole in living Pelvetia compressa zygotes.
Topics: Actins; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Dinitrobenzenes; Eukaryota; Fertilization; Light; Phalloidine; Rhodamines; Saponins; Sulfanilamides; Thiazoles; Thiazolidines; Zygote | 1999 |
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
Topics: Acyl-CoA Oxidase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Hypoglycemic Agents; Insulin; Ligands; Lipid Metabolism; Liver; Male; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Obesity; Organ Size; Oxidoreductases; Radioligand Assay; Rats; Rats, Wistar; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transcriptional Activation; Triglycerides | 1998 |
Synthesis of proto-oncogene proteins and cyclins depends on intact microfilaments.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cyclin A; Cyclin D1; Cyclin E; Cyclins; Cytochalasin D; Fibroblasts; Humans; Protein Biosynthesis; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Thiazoles; Thiazolidines | 1998 |
Effects of moguisteine on the cough reflex induced by afferent electrical stimulation of the superior laryngeal nerve in guinea pigs.
Topics: Aerosols; Animals; Anticoagulants; Antitussive Agents; Citric Acid; Codeine; Cough; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Injections, Intravenous; Injections, Intraventricular; Laryngeal Nerves; Reflex; Thiazoles; Thiazolidines | 1998 |
3-(5-Dimethylamino-1-naphthalenesulphonyl)-2-(3-pyridyl)thiazolidine (YHI-1) selectively inhibits human immunodeficiency virus type 1.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cysteine; Drug Resistance; Fishes; HIV Core Protein p24; HIV Protease; HIV-1; Humans; Molecular Structure; Naphthalenes; Nevirapine; Reverse Transcriptase Inhibitors; Thiazoles; Thiazolidines; Virus Replication | 1998 |
Possible role of platelet-activating factor in the in vivo expression of tissue factor in neutrophils.
Topics: Animals; Aspartate Aminotransferases; Blood Coagulation; Cholangitis; Disease Models, Animal; Leukocytes; Liver; Male; Neutrophils; Platelet Activating Factor; Rabbits; Thiazoles; Thiazolidines; Thromboplastin | 1998 |
Synthesis and reactivities of 3-indocyanine-green-acyl-1,3-thiazolidine-2-thione (ICG-ATT) as a new near-infrared fluorescent-labeling reagent.
Topics: Acylation; Animals; Cattle; Fluorescent Dyes; Immunoglobulin G; Indicators and Reagents; Indocyanine Green; Molecular Structure; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines; Thiones | 1998 |
Cytochalasin D and latrunculin affect chromosome behaviour during meiosis in crane-fly spermatocytes.
Topics: Actins; Anaphase; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Immobilized; Chromosome Segregation; Cytochalasin D; Diptera; In Vitro Techniques; Kinetochores; Male; Meiosis; Metaphase; Microscopy, Phase-Contrast; Myosins; Spermatocytes; Spindle Apparatus; Thiazoles; Thiazolidines | 1998 |
Effects of CP-060S, a novel cardioprotective drug, on cardiac function and myocardial oxygen consumption.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Heart; Heart Rate; Male; Myocardium; Oxygen Consumption; Sodium Channels; Thiazoles; Thiazolidines | 1999 |
Acto-myosin drug effects and aqueous outflow function.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cell Survival; Cells, Cultured; Diacetyl; Microscopy, Fluorescence; Myosins; Swine; Thiazoles; Thiazolidines; Trabecular Meshwork | 1999 |
Antiischemic effects of CP-060S, an inhibitor of pathologically modified sodium channels, assessed in the canine experimental model of angina pectoris.
Topics: Angina Pectoris; Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Female; Male; Myocardial Ischemia; Myocardium; Sodium Channel Blockers; Sodium Channels; Thiazoles; Thiazolidines; Time Factors; Ventricular Function, Left | 1999 |
Effects of rhizopodin and latrunculin B on the morphology and on the actin cytoskeleton of mammalian cells.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytoskeleton; Fibroblasts; Fluorescent Antibody Technique; Kidney; Macrolides; Mice; Microscopy, Electron; Oxazoles; Thiazoles; Thiazolidines | 1999 |
The role of actin microfilaments in the down-regulation of the degranulation response in RBL-2H3 mast cells.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Degranulation; Cytochalasin D; Dinitrophenols; Dose-Response Relationship, Immunologic; Down-Regulation; Haptens; Leukemia, Basophilic, Acute; Marine Toxins; Mast Cells; Porifera; Rats; Receptors, IgE; Serum Albumin, Bovine; Signal Transduction; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1999 |
Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway.
Topics: 3T3 Cells; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinases; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Cycle Proteins; Cell Division; Cytochalasin D; Cytoskeleton; Enzyme Activation; Epidermal Growth Factor; Growth Substances; GTP-Binding Proteins; Integrins; Luciferases; Mice; rhoA GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines; Transfection | 1999 |
Carbon disulphide absorption during xanthate reagent mixing in a gold mine concentrator.
Topics: Adult; Carbon Disulfide; Fatigue; Gold; Humans; Male; Mining; Nausea; Occupational Diseases; Thiazoles; Thiazolidines; Thiones | 1998 |
N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain.
Topics: Acetylcysteine; Animals; Brain; Cells, Cultured; Cysteine; Female; Glutathione; Methionine; Neurons; Pregnancy; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1999 |
Design, synthesis, and dopamine receptor modulating activity of spiro bicyclic peptidomimetics of L-prolyl-L-leucyl-glycinamide.
Topics: Animals; Binding, Competitive; Dopamine Agents; Drug Design; Lactams; Models, Molecular; Molecular Mimicry; Molecular Structure; MSH Release-Inhibiting Hormone; Protein Structure, Secondary; Rats; Receptors, Dopamine D2; Spiro Compounds; Structure-Activity Relationship; Thiazines; Thiazoles; Thiazolidines; X-Ray Diffraction | 1999 |
Latrunculin-A causes mydriasis and cycloplegia in the cynomolgus monkey.
Topics: Accommodation, Ocular; Animals; Anterior Chamber; Bridged Bicyclo Compounds, Heterocyclic; Ciliary Body; Dose-Response Relationship, Drug; Drug Combinations; Iris; Macaca fascicularis; Macaca mulatta; Marine Toxins; Muscle Relaxation; Muscle, Smooth; Mydriasis; Ophthalmic Solutions; Phenylephrine; Pilocarpine; Porifera; Pupil; Refraction, Ocular; Thiazoles; Thiazolidines | 1999 |
Enhancement of cytotoxicity of hydrogen peroxide by hyperthermia in chinese hamster ovary cells: role of antioxidant defenses.
Topics: Acetylcysteine; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Glutathione; Hot Temperature; Hydrogen Peroxide; Intracellular Fluid; Mesna; Oxidation-Reduction; Protective Agents; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
2-(3-Pyridyl)thiazolidine-4-carboxamide derivatives. III.) Synthesis of metabolites and metabolism of 2-(3-pyridyl)thiazolidine-4-carboxamides YM461 and YM264 as platelet-activating factor (PAF) receptor antagonists.
Topics: Administration, Oral; Animals; Area Under Curve; Biotransformation; Chromatography, High Pressure Liquid; Dogs; In Vitro Techniques; Injections, Intravenous; Macaca mulatta; Male; Piperazines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rabbits; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1999 |
The anti-ischemic effects of CP-060S during pacing-induced ischemia in anesthetized dogs.
Topics: Anesthesia; Animals; Benzothiazoles; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dogs; Drug Synergism; Electrocardiography; Ischemia; Male; Piperidines; Thiazoles; Thiazolidines | 1999 |
Stereoselective metabolism of tazofelone, an anti-inflammatory bowel disease agent, in rats and dogs and in human liver microsomes.
Topics: Administration, Oral; Animals; Area Under Curve; Blood Proteins; Dogs; Female; Half-Life; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Injections, Intravenous; Male; Microsomes, Liver; Phenols; Protein Binding; Rats; Rats, Inbred F344; Stereoisomerism; Sulfoxides; Thiazoles; Thiazolidines | 1999 |
The role of local actin instability in axon formation.
Topics: Actins; Animals; Axons; Bacterial Proteins; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Cells, Cultured; Cytochalasin D; Growth Cones; GTP Phosphohydrolases; Hippocampus; Microtubules; Neurites; Phenotype; Pseudopodia; Rats; Signal Transduction; Thiazoles; Thiazolidines | 1999 |
A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans.
Topics: Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Southern; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Deoxyribonucleases, Type II Site-Specific; DNA; Exons; Gene Library; Humans; Leukocytes; Male; Mixed Function Oxygenases; Molecular Sequence Data; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Restriction Fragment Length; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Thiazoles; Thiazolidines | 1999 |
(3-substituted benzyl)thiazolidine-2,4-diones as structurally new antihyperglycemic agents.
Topics: Animals; Blood Glucose; Hypoglycemic Agents; Insulin; Mice; Mice, Obese; Pioglitazone; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Thiazolidines; Triglycerides | 1999 |
Latrunculin-A increases outflow facility in the monkey.
Topics: Actins; Animals; Anterior Chamber; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cattle; Cell Adhesion; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Macaca fascicularis; Macaca mulatta; Marine Toxins; Ophthalmic Solutions; Porifera; Thiazoles; Thiazolidines; Time Factors; Trabecular Meshwork; Vinculin | 1999 |
New actin mutants allow further characterization of the nucleotide binding cleft and drug binding sites.
Topics: Actins; Adenosine Triphosphate; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Endocytosis; Genes, Fungal; Models, Molecular; Mutagenesis, Site-Directed; Nucleotides; Phenotype; Pyrans; Receptors, Drug; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 1999 |
Preliminary external quality assessment for the biological monitoring of carbon disulfide with urinary 2-thiothiazolidine-4-carboxylic acid.
Topics: Bias; Biomarkers; Carbon Disulfide; Dose-Response Relationship, Drug; Environmental Monitoring; Humans; Laboratories; Occupational Exposure; Quality Control; Reproducibility of Results; Thiazoles; Thiazolidines | 1999 |
S 17092-1, a highly potent, specific and cell permeant inhibitor of human proline endopeptidase.
Topics: Alzheimer Disease; Aminopeptidases; Brain; Calpain; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Endopeptidases; Humans; Hydrolysis; Indoles; Inhibitory Concentration 50; Kinetics; Peptidyl-Dipeptidase A; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Thiazoles; Thiazolidines | 1999 |
Microtubules, but not actin microfilaments, regulate vacuole motility and morphology in hyphae of Pisolithus tinctorius.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cryopreservation; Cytochalasin B; Cytochalasin D; Dinitrobenzenes; Dose-Response Relationship, Drug; Freeze Substitution; Fungi; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Nocodazole; Sulfanilamides; Thiazoles; Thiazolidines; Vacuoles | 1999 |
Ssp1 promotes actin depolymerization and is involved in stress response and new end take-off control in fission yeast.
Topics: Actins; Adaptation, Physiological; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Fungal Proteins; HSP70 Heat-Shock Proteins; Mitogen-Activated Protein Kinases; Mutation; Oxidative Stress; Phenotype; Protein Kinases; Repressor Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines | 1999 |
A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.
Topics: Adipocytes; Animals; Binding Sites; Cell Differentiation; Cell Line; Chlorocebus aethiops; Crystallography, X-Ray; Humans; Kinetics; Ligands; Mice; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Nuclear Proteins; Protein Structure, Secondary; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Transfection | 1999 |
Characterization of the mammalian septin H5: distinct patterns of cytoskeletal and membrane association from other septin proteins.
Topics: 3T3 Cells; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Membrane; COS Cells; Cytoskeletal Proteins; Cytoskeleton; GTP Phosphohydrolases; Mice; Precipitin Tests; Recombinant Fusion Proteins; Septins; Telophase; Thiazoles; Thiazolidines; Tissue Distribution | 1999 |
A role of actin filament in synaptic transmission and long-term potentiation.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; In Vitro Techniques; Long-Term Potentiation; Phalloidine; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; Synaptic Transmission; Thiazoles; Thiazolidines | 1999 |
Structure-activity relationship of small-sized HIV protease inhibitors containing allophenylnorstatine.
Topics: Administration, Oral; Animals; Biological Availability; Cell Line; Dipeptides; Dogs; Drug Evaluation, Preclinical; HIV Protease Inhibitors; HIV-1; Inhibitory Concentration 50; Injections, Intravenous; Oligopeptides; Phenylbutyrates; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1999 |
Determination of urinary 2-thiazolidinethione-4-carboxylic acid after exposure to alkylene bisdithiocarbamates using gas chromatography-mass spectrometry.
Topics: Calibration; Fungicides, Industrial; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Thiazoles; Thiazolidines; Thiocarbamates | 1999 |
A cytoskeletal localizing domain in the cyclase-associated protein, CAP/Srv2p, regulates access to a distant SH3-binding site.
Topics: Actins; Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Amino Acid Sequence; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cyclic AMP; Cytoskeletal Proteins; Cytoskeleton; Drosophila Proteins; Fungal Proteins; Glucose; GTP-Binding Proteins; Microfilament Proteins; Molecular Sequence Data; Mutation; Protein Binding; ras Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; src Homology Domains; Thiazoles; Thiazolidines | 1999 |
Rvs167p, the budding yeast homolog of amphiphysin, colocalizes with actin patches.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytoskeleton; Fungal Proteins; Genotype; Green Fluorescent Proteins; Luminescent Proteins; Marine Toxins; Microfilament Proteins; Nerve Tissue Proteins; Polymerase Chain Reaction; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 1999 |
Regulatory light chain phosphorylation and the assembly of myosin II into the cytoskeleton of microcapillary endothelial cells.
Topics: Actins; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capillaries; Cattle; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Myosin Light Chains; Myosins; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Staurosporine; Thiazoles; Thiazolidines | 1999 |
Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Eicosanoids; Fatty Acids; Fatty Acids, Unsaturated; Gene Expression Regulation; Genes, Reporter; Humans; Hydroxyeicosatetraenoic Acids; Inhibitory Concentration 50; Kinetics; Ligands; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidines; Transcription Factors; Transfection | 1999 |
Simultaneous analysis of urinary 2-thiothiazolidine-4-carboxylic acid and thiocarbamide as a biological exposure index for carbon disulfide exposure.
Topics: Animals; Carbon Disulfide; Environmental Exposure; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Thiourea; Urea | 1999 |
Stimulus-induced selective association of actin-associated proteins (alpha-actinin) and protein kinase C isoforms with the cytoskeleton of human neutrophils.
Topics: Actinin; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cells, Cultured; Chemotactic Factors; Cytochalasin D; Cytoskeleton; Enzyme Activation; Humans; Isoenzymes; Myosins; Neutrophil Activation; Neutrophils; Phosphoprotein Phosphatases; Polymers; Protein Kinase C; Protein Phosphatase 2; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Vinculin | 1999 |
Synthesis and dopamine receptor modulating activity of substituted bicyclic thiazolidine lactam peptidomimetics of L-prolyl-L-leucyl-glycinamide.
Topics: Animals; Crystallography, X-Ray; Dopamine Agents; Lactams; Male; Models, Molecular; Molecular Mimicry; Molecular Structure; MSH Release-Inhibiting Hormone; Oxidopamine; Parkinson Disease, Secondary; Pyrrolidines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1999 |
DAip1, a Dictyostelium homologue of the yeast actin-interacting protein 1, is involved in endocytosis, cytokinesis, and motility.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Movement; Cytoplasm; Dictyostelium; Endocytosis; Gene Deletion; Gene Expression; Giant Cells; Microfilament Proteins; Molecular Sequence Data; Phagocytosis; Pinocytosis; Polymers; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines | 1999 |
Cortexillin I is required for development in Polysphondylium.
Topics: Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Chemotaxis; Cloning, Molecular; Cytoskeleton; Dimerization; Gene Dosage; Gene Expression Regulation, Developmental; Microfilament Proteins; Molecular Sequence Data; Morphogenesis; Mutation; Myxomycetes; Polymerase Chain Reaction; Protein Isoforms; Protozoan Proteins; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines | 1999 |
Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 2. Structure-activity relationships of thiazolidinone derivatives.
Topics: Animals; Antioxidants; Aorta; Calcium; Calcium Channels; Calcium Channels, L-Type; Chromatography, High Pressure Liquid; Coronary Circulation; Crystallography, X-Ray; Dogs; Glycine max; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Lipoxygenase; Male; Models, Molecular; Muscle, Smooth, Vascular; Myocardium; Phenols; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1999 |
Influence of dietary iodine on drug-induced hypothyrodism in the rat.
Topics: Animals; Antithyroid Agents; Chlorpromazine; Clomipramine; Female; Hypothyroidism; Iodine; Lactoperoxidase; Organ Size; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Thyroid Gland; Thyrotropin | 1999 |
Actin polymerization stimulated by contractile activation regulates force development in canine tracheal smooth muscle.
Topics: Acetylcholine; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dogs; Muscle Contraction; Muscle, Smooth; Myosin Light Chains; Phosphorylation; Polymers; Thiazoles; Thiazolidines; Trachea | 1999 |
Separation of N-nitrosoamino acids by C18 reversed-phase ion-pair high-performance liquid chromatography and compatible detection by electrospray ionization mass spectrometry.
Topics: Anions; Chlorides; Chromatography, High Pressure Liquid; Mass Spectrometry; Nitrosamines; Nitroso Compounds; Solvents; Thiazoles; Thiazolidines | 1999 |
Purification and characterization of 5-oxo-L-prolinase from Paecilomyces varioti F-1, an ATP-dependent hydrolase active with L-2-oxothiazolidine-4-carboxylic acid.
Topics: Amidohydrolases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Paecilomyces; Pyrrolidonecarboxylic Acid; Sulfhydryl Reagents; Thiazoles; Thiazolidines | 1999 |
Post-translational regulation of AP-1 transcription factor DNA-binding activity in the rat conceptus.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbon-Oxygen Lyases; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Embryo, Mammalian; Female; Genes, jun; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Phosphorylation; Pregnancy; Protein Biosynthesis; Protein Kinases; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Transcription Factor AP-1; Tumor Cells, Cultured | 1999 |
Diatom gliding is the result of an actin-myosin motility system.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasins; Diacetyl; Diatoms; Dinitrobenzenes; Enzyme Inhibitors; Microtubules; Movement; Myosins; Nocodazole; Sulfanilamides; Thiazoles; Thiazolidines | 1999 |
The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle.
Topics: Actins; Anaphase; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; CDC28 Protein Kinase, S cerevisiae; Cell Cycle; Cell Cycle Proteins; Cell Polarity; Cyclin B; Dyneins; Fungal Proteins; Genes, Fungal; Hydroxyurea; Microfilament Proteins; Microtubules; Mutation; Nocodazole; Nuclear Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spindle Apparatus; Temperature; Thiazoles; Thiazolidines; Tropomyosin | 1999 |
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.
Topics: Actins; Adrenergic beta-Agonists; Binding Sites; Biotinylation; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Line; Endocytosis; Endosomes; Humans; Isoproterenol; Lysosomes; Molecular Sequence Data; Phosphoproteins; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; Serine; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidines | 1999 |
Actin-organelle interaction: association with chloroplast in arabidopsis leaf mesophyll cells.
Topics: Actins; Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Chloroplasts; Dinitrobenzenes; Microscopy, Fluorescence; Microtubules; Molecular Sequence Data; Organelles; Plant Leaves; Protein Binding; Sequence Homology, Amino Acid; Sulfanilamides; Thiazoles; Thiazolidines | 1999 |
l-2-oxothiazolidine-4-carboxylic acid modulates function of peritoneal mesothelial cells in vitro.
Topics: Cell Division; Cells, Cultured; Dialysis Solutions; Dose-Response Relationship, Drug; Epithelial Cells; Free Radicals; Glutathione; Humans; Hyaluronic Acid; Hydrogen Peroxide; In Vitro Techniques; Interleukin-6; Peritoneal Cavity; Peritoneal Dialysis; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
Effects in vitro of several antioxidants on the natural killer function of aging mice.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Killer Cells, Natural; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Peritoneum; Spleen; Thiazoles; Thiazolidines; Thymus Gland; Vitamin E | 1999 |
Spatial control of coated-pit dynamics in living cells.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Clathrin; Coated Pits, Cell-Membrane; COS Cells; Endocytosis; Female; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins; Luminescent Proteins; Marine Toxins; Mice; Placenta; Pregnancy; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 1999 |
The actin cytoskeleton is required to elaborate and maintain spatial patterning during trichome cell morphogenesis in Arabidopsis thaliana.
Topics: Actins; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Depsipeptides; Microtubules; Morphogenesis; Mutagenesis; Peptides, Cyclic; Phalloidine; Phenotype; Plants, Genetically Modified; Thiazoles; Thiazolidines | 1999 |
In vitro effect of glutathione precursors on cytotoxicity of amino acids to human mesothelial cells.
Topics: Acetylcysteine; Amino Acids; Biological Transport; Cell Membrane; Cells, Cultured; Epithelial Cells; Glutathione; Growth Inhibitors; Humans; Intracellular Fluid; Peritoneum; Potassium; Protein Precursors; Pyrrolidonecarboxylic Acid; Rubidium Radioisotopes; Thiazoles; Thiazolidines | 1999 |
Synthesis and in vitro anti-HIV activity in human monocyte-derived macrophages of 2-oxothiazolidine-4(R)-carboxylic acid derivatives.
Topics: Anti-HIV Agents; HIV-1; Humans; Macrophages; Monocytes; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1999 |
Autoregulation of actin synthesis requires the 3'-UTR of actin mRNA and protects cells from actin overproduction.
Topics: 3' Untranslated Regions; 3T3 Cells; Actins; Animals; Base Sequence; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Depsipeptides; DNA Primers; Gene Expression Regulation; Mice; Mice, Inbred BALB C; Peptides, Cyclic; RNA, Messenger; Sequence Deletion; Thiazoles; Thiazolidines | 1999 |
Amelioration by KRP-297, a new thiazolidinedione, of impaired glucose uptake in skeletal muscle from obese insulin-resistant animals.
Topics: Animals; Blood Glucose; Glucose; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Thiazoles; Thiazolidines | 1999 |
Latrunculin B has different effects on pollen germination and tube growth.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Pollen; Reproduction; Thiazoles; Thiazolidines; Zea mays | 1999 |
Effects of CP-060S, a novel Ca(2+) channel blocker, on oxidative stress in cultured cardiac myocytes.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Diltiazem; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; L-Lactate Dehydrogenase; Myocardium; Oxidants; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles; Thiazolidines; Thiourea | 1999 |
Improvement of murine immune functions in vitro by thioproline.
Topics: Animals; Antioxidants; Chemotaxis; Female; Killer Cells, Natural; Lymphocytes; Macrophages; Mice; Mice, Inbred BALB C; Phagocytosis; Thiazoles; Thiazolidines | 1999 |
Polyglutamylation of atlantic cod tubulin: immunochemical localization and possible role in pigment granule transport.
Topics: Animals; Antibodies; Biological Transport; Blotting, Western; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chromatophores; Dyneins; Fishes; Immunohistochemistry; Kinesins; Microtubules; Pigments, Biological; Polyglutamic Acid; Thiazoles; Thiazolidines; Tissue Distribution; Tubulin | 1999 |
Changes in several functions of murine peritoneal macrophages by N-acetylcysteine and thioproline ingestion. Comparative effect between two strains of mice.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Adhesion; Chemotaxis; Dietary Supplements; Female; In Vitro Techniques; Interleukin-1; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Phagocytosis; Species Specificity; Superoxides; Thiazoles; Thiazolidines | 1999 |
Effect of a diet supplemented with thioproline on murine macrophage function in a model of premature ageing.
Topics: Aging; Animals; Antioxidants; Cell Adhesion; Chemotaxis; Dietary Supplements; Female; Leukocytes; Macrophages, Peritoneal; Mice; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Superoxides; Thiazoles; Thiazolidines | 1999 |
In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist.
Topics: Arginine; Aspirin; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Humans; Oligopeptides; Peptide Fragments; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thrombin; Serine Endopeptidases; Sulfonamides; Thiazoles; Thiazolidines; Thrombin | 1999 |
Drug-induced changes of cytoskeletal structure and mechanics in fibroblasts: an atomic force microscopy study.
Topics: 3T3 Cells; Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Colchicine; Cytochalasin B; Cytochalasin D; Cytoskeleton; Demecolcine; Depsipeptides; Elasticity; Fibroblasts; Kinetics; Marine Toxins; Mice; Microscopy, Atomic Force; Microscopy, Fluorescence; Microtubules; Paclitaxel; Peptides, Cyclic; Rats; Stress, Mechanical; Thiazoles; Thiazolidines | 2000 |
In vivo dynamics of the F-actin-binding protein neurabin-II.
Topics: Actins; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Compartmentation; Cytochalasin D; Cytoskeleton; Epidermal Growth Factor; Green Fluorescent Proteins; Luminescent Proteins; Microfilament Proteins; Microscopy, Fluorescence; Nerve Tissue Proteins; PC12 Cells; Protein Binding; rac1 GTP-Binding Protein; Rats; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2000 |
Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Cerebral Cortex; Cytochalasin D; Dendrites; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Homeostasis; Mice; Neurons; Neurotoxins; Nucleic Acid Synthesis Inhibitors; Oxygen; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Thiazoles; Thiazolidines | 2000 |
Saccharomyces cerevisiae Arc35p works through two genetically separable calmodulin functions to regulate the actin and tubulin cytoskeletons.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Alleles; Bridged Bicyclo Compounds, Heterocyclic; Calmodulin; Cell Cycle Proteins; Cell Division; Cytoskeletal Proteins; Cytoskeleton; Fungal Proteins; G1 Phase; Gene Expression Regulation, Fungal; Macromolecular Substances; Metaphase; Microtubules; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Temperature; Thiazoles; Thiazolidines; Tubulin | 2000 |
L-2-[(13)C]oxothiazolidine-4-carboxylic acid: a probe for precursor mobilization for glutathione synthesis.
Topics: Acetaminophen; Adult; Aged; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Cysteine; Female; Glutathione; Humans; Kinetics; Male; Middle Aged; Models, Biological; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2000 |
Evidence that actin and myosin are involved in the poleward flux of tubulin in metaphase kinetochore microtubules of crane-fly spermatocytes.
Topics: Acetylation; Actins; Actomyosin; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Diacetyl; Diptera; Enzyme Inhibitors; Kinetochores; Male; Marine Toxins; Metaphase; Microscopy, Confocal; Microtubules; Nocodazole; Nucleic Acid Synthesis Inhibitors; Spermatocytes; Spindle Apparatus; Thiazoles; Thiazolidines; Tubulin | 2000 |
Agonist-induced changes in cell shape during regulated secretion in rat pancreatic acini.
Topics: Actins; Amylases; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cholecystokinin; Cytochalasin D; Cytoskeleton; Diacetyl; Enzyme Inhibitors; Fluorescent Antibody Technique; Male; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Video; Myosin Light Chains; Myosins; Nucleic Acid Synthesis Inhibitors; Pancreas; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2000 |
Microfilament network is needed for the endocytosis of water channels and not for apical membrane insertion upon vasopressin action.
Topics: Actin Cytoskeleton; Animals; Aquaporins; Bridged Bicyclo Compounds, Heterocyclic; Bufo marinus; Cell Membrane; Cytochalasin D; Endocytosis; Horseradish Peroxidase; Mercuric Chloride; Thiazoles; Thiazolidines; Urinary Bladder; Vasopressins; Water | 2000 |
The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat.
Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethanol; Glutathione; Intubation, Gastrointestinal; Kupffer Cells; Liver; Liver Diseases; Male; Necrosis; NF-kappa B; Prodrugs; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; RNA, Messenger; Thiazoles; Thiazolidines; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Elevation of glutathione level and activation of glutathione-related enzymes affect virus infection in tobacco.
Topics: Ascorbate Peroxidases; Cyclohexane Monoterpenes; Glutathione; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Malondialdehyde; Monoterpenes; Nicotiana; Peroxidases; Plant Diseases; Plant Leaves; Plants, Toxic; Pyrrolidonecarboxylic Acid; Terpenes; Thiazoles; Thiazolidines; Tobacco Mosaic Virus | 1999 |
A checkpoint that monitors cytokinesis in Schizosaccharomyces pombe.
Topics: Actins; Actomyosin; Alleles; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Division; G2 Phase; Glucosyltransferases; Interphase; Membrane Proteins; Mitosis; Mutagenesis; Nuclear Proteins; Protein-Tyrosine Kinases; Saccharomyces cerevisiae; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Thiazoles; Thiazolidines | 2000 |
Microtubules, but not actin filaments, drive daughter cell budding and cell division in Toxoplasma gondii.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcimycin; Cell Division; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dinitrobenzenes; Fibroblasts; Growth Inhibitors; Humans; Ionophores; Microscopy, Electron; Microtubules; Nocodazole; Organelles; Paclitaxel; Sulfanilamides; Thiazoles; Thiazolidines; Toxoplasma | 2000 |
Clustering of delta glutamate receptors is regulated by the actin cytoskeleton in the dendritic spines of cultured rat Purkinje cells.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dendrites; Dimethyl Sulfoxide; Image Processing, Computer-Assisted; Microscopy, Confocal; Microscopy, Fluorescence; Nerve Tissue Proteins; Neuronal Plasticity; Nocodazole; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Wistar; Receptor Aggregation; Receptors, Glutamate; Synaptic Transmission; Thiazoles; Thiazolidines | 2000 |
Effect of latrunculin-B on outflow facility in monkeys.
Topics: Animals; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Macaca fascicularis; Marine Toxins; Thiazoles; Thiazolidines; Trabecular Meshwork | 2000 |
A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets. Evidence for conformational coupling.
Topics: Actins; Biological Transport; Blood Platelets; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Membrane; Cytochalasin D; Cytoskeleton; Depsipeptides; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate; Marine Toxins; Models, Biological; Oxazoles; Peptides, Cyclic; Thiazoles; Thiazolidines | 2000 |
Mechanics of living cells measured by laser tracking microrheology.
Topics: Actins; Animals; Biomechanical Phenomena; Biophysical Phenomena; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; COS Cells; Cytoskeleton; Elasticity; Lasers; Microscopy, Electron; Rheology; Thiazoles; Thiazolidines; Viscosity | 2000 |
Functional interactions between the p35 subunit of the Arp2/3 complex and calmodulin in yeast.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Alleles; Bridged Bicyclo Compounds, Heterocyclic; Calmodulin; Cytoskeletal Proteins; Cytoskeleton; Endocytosis; Fungal Proteins; Microscopy, Fluorescence; Mutation; Precipitin Tests; Protein Binding; Thiazoles; Thiazolidines; Two-Hybrid System Techniques; Yeasts | 2000 |
Titanium enolates of thiazolidinethione chiral auxiliaries: versatile tools for asymmetric aldol additions.
Topics: Aldehydes; Chemistry, Organic; Indicators and Reagents; Sparteine; Stereoisomerism; Thiazoles; Thiazolidines; Titanium | 2000 |
Microtubule stabilization leads to growth reorientation in Arabidopsis trichomes.
Topics: Actins; Arabidopsis; Arabidopsis Proteins; Benzamides; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Calmodulin-Binding Proteins; Cell Division; Cell Size; Dinitrobenzenes; Genes, Plant; Microscopy, Confocal; Microscopy, Electron, Scanning; Microtubule-Associated Proteins; Microtubules; Multiprotein Complexes; Mutation; Paclitaxel; Phenotype; Plant Proteins; Plants, Genetically Modified; Recombinant Fusion Proteins; Sulfanilamides; Thiazoles; Thiazolidines | 2000 |
Transport of peptide-MHC class II complexes in developing dendritic cells.
Topics: Animals; Antibodies, Monoclonal; Antigen Presentation; Antigens, CD; B-Lymphocytes; B7-2 Antigen; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; Dendritic Cells; Endocytosis; Endosomes; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Kinetics; Ligands; Lipopolysaccharides; Lysosomes; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Muramidase; Peptide Fragments; Receptors, Antigen, T-Cell; Thiazoles; Thiazolidines | 2000 |
Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.
Topics: Administration, Oral; Animals; Chromans; Diabetes Mellitus; Fatty Acids; Hypoglycemic Agents; Liver; Male; Muscle, Skeletal; Obesity; Oxidation-Reduction; Palmitic Acid; Rats; Rats, Zucker; Reference Values; Substrate Specificity; Thiazoles; Thiazolidinediones; Thiazolidines; Triglycerides; Troglitazone | 2000 |
Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts.
Topics: Actins; Actomyosin; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Extracellular Matrix; Fibroblasts; Genes, Reporter; Green Fluorescent Proteins; Humans; Indicators and Reagents; Luminescent Proteins; Microfilament Proteins; Paxillin; Phosphoproteins; Recombinant Proteins; Tensins; Thiazoles; Thiazolidines; Transfection | 2000 |
Rev-dependent association of the intron-containing HIV-1 gag mRNA with the nuclear actin bundles and the inhibition of its nucleocytoplasmic transport by latrunculin-B.
Topics: Actins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Nucleus; Cytoplasm; DNA, Recombinant; Dose-Response Relationship, Drug; Exportin 1 Protein; Fluorescent Antibody Technique, Indirect; Gene Products, gag; Gene Products, rev; GTP Phosphohydrolases; HeLa Cells; Humans; In Situ Hybridization, Fluorescence; Introns; Karyopherins; Microscopy, Immunoelectron; Plasmids; Protein Binding; Protein Precursors; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; Ribonucleoproteins; RNA Precursors; RNA, Messenger; RNA, Viral; Thiazoles; Thiazolidines | 2000 |
Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Division; Cell Polarity; Fungal Proteins; Green Fluorescent Proteins; Luminescent Proteins; Microscopy, Video; Mutation; Myosin Heavy Chains; Myosin Type II; Myosin Type V; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines | 2000 |
Involvement of ATP-sensitive K(+) channels in the anti-tussive effect of moguisteine.
Topics: Animals; Antitussive Agents; ATP-Binding Cassette Transporters; Cough; Disease Models, Animal; Drug Interactions; Glyburide; Guinea Pigs; KATP Channels; Male; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Thiazoles; Thiazolidines | 2000 |
Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight.
Topics: Acyl-CoA Oxidase; Animals; Apolipoprotein A-I; Apolipoprotein C-III; Apolipoproteins C; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Male; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Oxidoreductases; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors; Transcription Factors; Triglycerides | 2000 |
Effects of L-2-oxothiazolidine-4-carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases.
Topics: Acrolein; Alkylation; Animals; Antineoplastic Agents, Alkylating; Biotransformation; Cell Division; Cyclophosphamide; Cysteine; Disease Progression; Drug Interactions; Drug Screening Assays, Antitumor; Female; Glutathione; Leukopenia; Liver Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2000 |
Motor proteins regulate force interactions between microtubules and microfilaments in the axon.
Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Axons; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Cytoplasm; Dyneins; Enzyme Inhibitors; Ethylmaleimide; Ganglia, Spinal; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Molecular Motor Proteins; Myosins; Neurons, Afferent; Nocodazole; Thiazoles; Thiazolidines | 2000 |
Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: maintenance of core components independent of actin filaments and microtubules.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Disks Large Homolog 4 Protein; Evoked Potentials; Excitatory Postsynaptic Potentials; Hippocampus; Intracellular Signaling Peptides and Proteins; Marine Toxins; Membrane Proteins; Microtubules; Nerve Tissue Proteins; Neurons; Octoxynol; Rats; Synapses; Thiazoles; Thiazolidines; Vincristine | 2000 |
Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium.
Topics: Animals; Aqueous Humor; Blood-Aqueous Barrier; Bridged Bicyclo Compounds, Heterocyclic; Cell Count; Cornea; Endothelium, Corneal; Eye Proteins; Female; Fluorescein; Fluorophotometry; Intraocular Pressure; Macaca fascicularis; Male; Marine Toxins; Ophthalmic Solutions; Permeability; Porifera; Thiazoles; Thiazolidines; Ultrasonography | 2000 |
The behaviour of the plasma membrane during plasmolysis: a study by UV microscopy.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Carbocyanines; Cell Membrane; Dinitrobenzenes; Fluorescent Dyes; Microscopy, Ultraviolet; Onions; Osmotic Pressure; Plant Epidermis; Sulfanilamides; Thiazoles; Thiazolidines | 2000 |
Cigarette smoking and urinary organic sulfides.
Topics: Adult; Biomarkers; Carbon Disulfide; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Humans; Male; Occupational Exposure; Smoking; Thiazoles; Thiazolidines | 2000 |
Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
Topics: Actins; Animals; Binding Sites; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Crystallography, X-Ray; Gelsolin; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Porifera; Protein Binding; Protein Conformation; Thiazoles; Thiazolidines; Yeasts | 2000 |
Disruption of actin impedes transmitter release in snake motor terminals.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Colubridae; Dose-Response Relationship, Drug; Electrophysiology; Endocytosis; Fluorescent Dyes; Motor Neurons; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines | 2000 |
Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A.
Topics: Actins; Adenosine Triphosphate; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Crystallization; Crystallography, X-Ray; Deoxyribonuclease I; Kinetics; Marine Toxins; Muscle, Skeletal; Rabbits; Thiazoles; Thiazolidines; Thymosin | 2000 |
Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell-Free System; Deoxyribonuclease I; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Activation; Ethyldimethylaminopropyl Carbodiimide; Guanosine Triphosphate; Humans; Magnesium; NADPH Oxidases; Neutrophils; Oxygen; Sodium Dodecyl Sulfate; Subcellular Fractions; Thiazoles; Thiazolidines; Time Factors | 2000 |
Actin filament disruption blocks cerebellar granule neurons at the unipolar stage of differentiation in vitro.
Topics: Actins; Animals; Axons; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Polarity; Cell Survival; Cells, Cultured; Cerebellum; Cytochalasin D; Cytoskeleton; Golgi Apparatus; Mice; Mice, Inbred C57BL; Neurons; Nucleic Acid Synthesis Inhibitors; Polymers; Thiazoles; Thiazolidines | 2000 |
The F-actin cytoskeleton modulates slow secretory components rather than readily releasable vesicle pools in bovine chromaffin cells.
Topics: Actins; Adrenal Glands; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Cattle; Cell Membrane; Chromaffin Cells; Cytoplasmic Granules; Cytoskeleton; Electrophysiology; Enzyme Inhibitors; Exocytosis; Marine Toxins; Membrane Potentials; Microscopy, Electron; Oxazoles; Phosphorylation; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 2000 |
TTCA measurements in biomonitoring of low-level exposure to carbon disulphide.
Topics: Adult; Carbon Disulfide; Female; Humans; Male; Middle Aged; Occupational Exposure; Reference Values; Sensitivity and Specificity; Thiazoles; Thiazolidines; Vegetables | 2000 |
Epidermal growth factor-mediated caveolin recruitment to early endosomes and MAPK activation. Role of cholesterol and actin cytoskeleton.
Topics: Actins; Animals; Biological Transport; Biomarkers; Bridged Bicyclo Compounds, Heterocyclic; Caveolin 1; Caveolins; Cell Compartmentation; Cell Membrane; Cholesterol; Cytochalasin D; Cytoskeleton; Endosomes; Epidermal Growth Factor; Filipin; Kidney; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Rats; Thiazoles; Thiazolidines; Vesicle-Associated Membrane Protein 3 | 2000 |
Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Polarity; Cell Wall; Fungal Proteins; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Protein Kinase C; Recombinant Proteins; rho GTP-Binding Proteins; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 2000 |
Actin disruption alters the localization of tau in the growth cones of cerebellar granule neurons.
Topics: Actins; Animals; Axons; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cells, Cultured; Cerebellar Cortex; Cytochalasin D; Cytoskeleton; Growth Cones; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurons; Nucleic Acid Synthesis Inhibitors; Polymers; tau Proteins; Thiazoles; Thiazolidines; Tubulin | 2000 |
Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats.
Topics: Administration, Oral; Animals; Cations; Cell Membrane; Cells, Cultured; Drug Combinations; Epithelium; Ethanol; Glutathione; Ion Channels; Male; Permeability; Prodrugs; Pulmonary Alveoli; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2000 |
Antithyroid action of tamoxifen in the rat: in vivo and in vitro studies.
Topics: Animals; Antithyroid Agents; Estrogen Receptor Modulators; Female; Iodine; Models, Molecular; Molecular Conformation; Rats; Rats, Wistar; Tamoxifen; Thiazoles; Thiazolidines; Thyroid Gland; Thyroid Hormones | 2000 |
Melanosome and erythrosome positioning regulates cAMP-induced movement in chromatophores from spotted triplefin, Grahamina capito.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotenoids; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fishes; In Vitro Techniques; Melanosomes; Norepinephrine; Skin Physiological Phenomena; Thiazoles; Thiazolidines | 2000 |
Three- and four-dimensional-quantitative structure activity relationship (3D/4D-QSAR) analyses of CYP2C9 inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Models, Molecular; Phenols; Protein Conformation; Quinolones; Reproducibility of Results; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2000 |
Co-deletion of the MSB3 and MSB4 coding regions affects bipolar budding and perturbs the organization of the actin cytoskeleton.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Diploidy; Fungal Proteins; Gene Deletion; Genetic Complementation Test; Green Fluorescent Proteins; GTPase-Activating Proteins; Haploidy; Intracellular Signaling Peptides and Proteins; Luminescent Proteins; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Subcellular Fractions; Thiazoles; Thiazolidines | 2000 |
Novel proline endopeptidase inhibitors do not modify Abeta40/42 formation and degradation by human cells expressing wild-type and swedish mutated beta-amyloid precursor protein.
Topics: Amyloid beta-Peptides; Cells, Cultured; Humans; Indoles; Peptide Fragments; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles; Thiazolidines | 2000 |
Effect of latrunculin-A on morphology and actin-associated adhesions of cultured human trabecular meshwork cells.
Topics: Actins; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Humans; Macrolides; Microscopy, Fluorescence; Microscopy, Video; Thiazoles; Thiazolidines; Trabecular Meshwork; Trans-Activators; Vinculin | 2000 |
Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p).
Topics: Actins; Adaptor Proteins, Signal Transducing; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; cdc42 GTP-Binding Protein; Cell Cycle; Chromatography, Gel; Conserved Sequence; Cytoskeletal Proteins; Cytoskeleton; Fungal Proteins; Genes, Dominant; Microfilament Proteins; Mutagenesis, Site-Directed; Plasmids; Precipitin Tests; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Temperature; Thiazoles; Thiazolidines; Time Factors; Two-Hybrid System Techniques | 2000 |
Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42.
Topics: 3T3 Cells; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line; Depsipeptides; Fibronectins; Mice; Microfilament Proteins; Muscle, Skeletal; Peptides, Cyclic; rac GTP-Binding Proteins; Recombinant Proteins; Stress, Mechanical; Thiazoles; Thiazolidines; Thrombospondin 1; Transfection; Vinculin | 2000 |
Mutations of arginine residues within the 146-KKRRK-150 motif of the ActA protein of Listeria monocytogenes abolish intracellular motility by interfering with the recruitment of the Arp2/3 complex.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Bacterial Proteins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Chromosomes, Bacterial; Cytoskeletal Proteins; Genes, Bacterial; Intracellular Fluid; Listeria monocytogenes; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Sequence Deletion; Thiazoles; Thiazolidines | 2000 |
The Cdc42p GTPase is targeted to the site of cell division in the fission yeast Schizosaccharomyces pombe.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Division; Contractile Proteins; Cytoskeleton; Green Fluorescent Proteins; Immunoblotting; Luminescent Proteins; Microfilament Proteins; Microscopy, Fluorescence; Profilins; Recombinant Fusion Proteins; Schizosaccharomyces; Temperature; Thiazoles; Thiazolidines; Time Factors; Tropomyosin | 2000 |
Redundancy of lamellipodia in locomoting Walker carcinosarcoma cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma 256, Walker; Cell Adhesion; Cell Movement; Cell Polarity; Cell Size; Elasticity; Marine Toxins; Pseudopodia; Rats; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured | 2000 |
Hormone-stimulated calcium release is inhibited by cytoskeleton-disrupting toxins in AR4-2J cells.
Topics: Aluminum Compounds; Animals; Bacterial Proteins; Bacterial Toxins; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Membrane Permeability; Cytochalasin D; Cytoskeleton; Cytosol; Fluorides; GTP-Binding Proteins; Hormones; Inositol 1,4,5-Trisphosphate; Pancreas; Pancreatic Neoplasms; Rats; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Type C Phospholipases | 2000 |
Rac is involved in early TCR signaling.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; CD3 Complex; Cytoskeleton; Gene Expression Regulation; Genetic Vectors; Humans; Inositol 1,4,5-Trisphosphate; Jurkat Cells; Mutation; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; rac GTP-Binding Proteins; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Thiazoles; Thiazolidines; Transfection; Tyrosine | 2000 |
Mechanisms of vasoinhibitory effect of cardioprotective agent, CP-060S, in rat aorta.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Cytosol; Dinoprost; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Phenylephrine; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
The actin-driven movement and formation of acetylcholine receptor clusters.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cortactin; Depsipeptides; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Microfilament Proteins; Microspheres; Muscles; Neuromuscular Junction; Peptides, Cyclic; Polymers; Receptors, Cholinergic; Sarcolemma; Synaptic Transmission; Thiazoles; Thiazolidines; Xenopus | 2000 |
A glucoamylase::GFP gene fusion to study protein secretion by individual hyphae of Aspergillus niger.
Topics: Actins; Aspergillus niger; Blotting, Southern; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Culture Media; Glucan 1,4-alpha-Glucosidase; Green Fluorescent Proteins; Luminescent Proteins; Microscopy, Fluorescence; Plasmids; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2000 |
Suppressors of mdm20 in yeast identify new alleles of ACT1 and TPM1 predicted to enhance actin-tropomyosin interactions.
Topics: Acetyltransferases; Actins; Alleles; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Fungal Proteins; Genes, Fungal; Genotype; Models, Molecular; Mutagenesis; Mutagenesis, Site-Directed; N-Terminal Acetyltransferase B; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Suppression, Genetic; Temperature; Thiazoles; Thiazolidines; Tropomyosin | 2000 |
Depletion of intracellular glutathione reduces mutations by nitric oxide-donating drugs.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Gamma Rays; Glutathione; Hypoxanthine Phosphoribosyltransferase; Mice; Mutagenesis; Mutagens; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Nitroprusside; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2000 |
Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization.
Topics: Actins; Amides; Animals; Aorta; Biomarkers; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cells, Cultured; Cytochalasin D; Depsipeptides; DNA-Binding Proteins; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, Reporter; Muscle, Smooth, Vascular; Nuclear Proteins; Peptides, Cyclic; Promoter Regions, Genetic; Pyridines; Rats; rhoA GTP-Binding Protein; Serum Response Factor; Signal Transduction; Stress Fibers; Thiazoles; Thiazolidines; Transcription, Genetic; Transfection | 2001 |
Cluster formation of alpha7-containing nicotinic receptors at interneuronal interfaces in cell culture.
Topics: Actins; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Cadherins; Cells, Cultured; Chick Embryo; Detergents; Ganglia, Parasympathetic; Interneurons; Iodine Radioisotopes; Marine Toxins; Microscopy, Fluorescence; Receptors, Nicotinic; Thiazoles; Thiazolidines | 2000 |
Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.
Topics: Actin Cytoskeleton; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; COS Cells; Cytoskeletal Proteins; Cytoskeleton; Humans; Immunoblotting; Male; Membrane Proteins; Mutagenesis, Site-Directed; Neuropeptides; Precipitin Tests; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Synapses; Thiazoles; Thiazolidines; Transfection; Two-Hybrid System Techniques | 2000 |
Role of microtubules and actin filaments in the movement of mitochondria in the axons and dendrites of cultured hippocampal neurons.
Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Axonal Transport; Axons; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytochalasin D; Dendrites; Hippocampus; Microtubules; Mitochondria; Neurons; Nocodazole; Nucleic Acid Synthesis Inhibitors; Rats; Thiazoles; Thiazolidines | 2000 |
Actin-dependent regulation of neurotransmitter release at central synapses.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Cytochalasin D; Depsipeptides; Egtazic Acid; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Marine Toxins; Mice; Nerve Tissue Proteins; Neurotransmitter Agents; Peptides, Cyclic; Presynaptic Terminals; Rats; Recombinant Fusion Proteins; Synapses; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines | 2000 |
Subcellular distribution of envoplakin and periplakin: insights into their role as precursors of the epidermal cornified envelope.
Topics: Actins; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Nucleus; Cells, Cultured; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Desmosomes; Dimerization; Epidermal Cells; Epidermis; Fluorescent Antibody Technique; Humans; Keratinocytes; Keratins; Membrane Proteins; Mice; Microscopy, Electron; Plakins; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Solubility; Thiazoles; Thiazolidines; Transfection | 2000 |
Cytoskeletal regulation of the platelet glycoprotein Ib/V/IX-von willebrand factor interaction.
Topics: Actin Cytoskeleton; Actins; Adenosine Diphosphate; Alprostadil; Animals; Antibodies, Monoclonal; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cricetinae; Cytochalasin D; Cytoskeleton; Depsipeptides; Humans; Mutagenesis, Site-Directed; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Stress, Mechanical; Thiazoles; Thiazolidines; Thrombasthenia; Transfection; von Willebrand Factor | 2000 |
Requirement of cortical actin organization for bombesin, endothelin, and EGF receptor internalization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Actins; Animals; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gastrin-Releasing Peptide; GTP-Binding Proteins; Iodine Radioisotopes; Kinetics; Mice; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Receptors, Bombesin; Receptors, Endothelin; Signal Transduction; Thiazoles; Thiazolidines | 2000 |
Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo.
Topics: Actin Cytoskeleton; Actins; Adenomatous Polyposis Coli Protein; Adherens Junctions; Animals; Armadillo Domain Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Size; Colchicine; Contractile Proteins; Cytochalasin D; Cytoskeletal Proteins; Drosophila melanogaster; Drosophila Proteins; Embryo, Nonmammalian; Female; Fluorescent Dyes; Insect Proteins; Microfilament Proteins; Microscopy, Confocal; Microtubules; Ovary; Phalloidine; Profilins; Thiazoles; Thiazolidines; Trans-Activators; Transcription Factors | 2000 |
The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane Structures; Cloning, Molecular; Cytoskeleton; Gene Deletion; Genes, Reporter; Inositol Polyphosphate 5-Phosphatases; Marine Toxins; Microscopy, Confocal; Microscopy, Fluorescence; Osmotic Pressure; Phosphatidylinositol 4,5-Diphosphate; Phosphoric Monoester Hydrolases; Promoter Regions, Genetic; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thiazoles; Thiazolidines; Time Factors | 2000 |
A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Actins; Adipocytes; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cytochalasin D; Cytoskeleton; Enzyme Activation; Glycogen Synthase Kinase 3; Growth Substances; Hormones; Humans; Insulin; Mice; Muscles; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Tumor Suppressor Proteins | 2000 |
Chloride channel activity of ClC-2 is modified by the actin cytoskeleton.
Topics: Actins; Amino Acid Sequence; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Cytochalasin D; Cytoskeleton; Ion Channel Gating; Molecular Sequence Data; Oocytes; Osmolar Concentration; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Static Electricity; Thiazoles; Thiazolidines; Xenopus laevis | 2000 |
Involvement of actin filaments and integrins in the binding step in collagen phagocytosis by human fibroblasts.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Collagen; Fibroblasts; Humans; Integrins; Phagocytosis; Receptors, Collagen; Thiazoles; Thiazolidines | 2001 |
Effects of latrunculin reveal requirements for the actin cytoskeleton during secretion from mast cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane Permeability; Cytoskeleton; Exocytosis; Flow Cytometry; Guanosine 5'-O-(3-Thiotriphosphate); Marine Toxins; Mast Cells; Microscopy, Confocal; p-Methoxy-N-methylphenethylamine; Rats; Thiazoles; Thiazolidines | 2001 |
Antioxidant compounds interfere with the 3.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Colorimetry; Coloring Agents; Culture Media; Dithiothreitol; Kinetics; Melatonin; Mercaptoethanol; Oxidation-Reduction; Pyrrolidines; Pyrrolidonecarboxylic Acid; Reagent Kits, Diagnostic; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Thiazolidines; Thiocarbamates; Vitamin E | 2000 |
Fatty-acyl-CoA thioesters inhibit recruitment of steroid receptor co-activator 1 to alpha and gamma isoforms of peroxisome-proliferator-activated receptors by competing with agonists.
Topics: Acyl Coenzyme A; Animals; Binding, Competitive; Fatty Acids; Histone Acetyltransferases; Ligands; Liver; Male; Muscles; Nuclear Receptor Coactivator 1; Plasmids; Protein Isoforms; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidines; Transcription Factors; Tritium | 2001 |
The human prostanoid DP receptor stimulates mucin secretion in LS174T cells.
Topics: Benzoates; Binding, Competitive; Cell Membrane; Colon; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Hydantoins; In Situ Hybridization; Mucins; Prostaglandin D2; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Thiazoles; Thiazolidines; Transcription, Genetic; Tritium; Tumor Cells, Cultured | 2000 |
Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function.
Topics: Animals; Behavior, Animal; Glutathione; Glutathione Reductase; Male; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Thiazoles; Thiazolidines; Up-Regulation | 2001 |
Contribution of cytoskeleton to the internalization of AMPA receptors.
Topics: Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Depsipeptides; Endocytosis; Glutamic Acid; Hippocampus; Marine Toxins; Neurons; Peptides, Cyclic; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thiazoles; Thiazolidines; Transferrin | 2001 |
ATP-dependent membrane assembly of F-actin facilitates membrane fusion.
Topics: Actins; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytochalasin D; Cytoplasm; Endosomes; Intracellular Membranes; Kinetics; Macrophages; Membrane Fusion; Mice; Phagosomes; Rheology; Thiazoles; Thiazolidines | 2001 |
Activation of beta1 integrins induces cell-cell adhesion.
Topics: Actins; Antibodies, Monoclonal; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cations, Divalent; Cell Adhesion; Collagen; Dose-Response Relationship, Immunologic; Epitopes; Fibronectins; Fibrosarcoma; Humans; Hybridomas; Immunohistochemistry; Integrin beta1; Laminin; Microscopy, Confocal; Models, Biological; Signal Transduction; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2001 |
Diverse regulation of microfilament assembly, production of TNF-alpha, and reactive oxygen intermediates by actin modulating substances and inhibitors of ADP-ribosylation in human monocytes stimulated with LPS.
Topics: Actin Cytoskeleton; Actins; Adenosine Diphosphate Ribose; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Depsipeptides; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; Phosphorylation; Polymers; Reactive Oxygen Species; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha | 2001 |
Use of abnormal preprophase bands to decipher division plane determination.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Nucleus; Nicotiana; Plants, Toxic; Prophase; Thiazoles; Thiazolidines | 2001 |
Latrunculin B-induced plant dwarfism: Plant cell elongation is F-actin-dependent.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Indoleacetic Acids; Mitosis; Plant Development; Plants; Thiazoles; Thiazolidines | 2001 |
Effects of cytochalasin D and latrunculin B on mechanical properties of cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chickens; Cytochalasin D; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Fibroblasts; Microscopy, Fluorescence; Thiazoles; Thiazolidines | 2001 |
Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; CHO Cells; Coated Pits, Cell-Membrane; COS Cells; Cricetinae; Cytochalasin D; Cytoskeleton; Depsipeptides; Endocytosis; Freeze Etching; Humans; K562 Cells; Microscopy, Fluorescence; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; Thiazoles; Thiazolidines; Time Factors; Transferrin; Tumor Cells, Cultured | 2000 |
Truncated brush border myosin I affects membrane traffic in polarized epithelial cells.
Topics: Actins; Animals; Biological Transport, Active; Bridged Bicyclo Compounds, Heterocyclic; Caco-2 Cells; Cell Polarity; Chickens; Dipeptidyl Peptidase 4; Endocytosis; Endosomes; Epithelial Cells; Humans; Microscopy, Immunoelectron; Microvilli; Models, Biological; Myosins; Peptide Fragments; Recombinant Proteins; Sequence Deletion; Thiazoles; Thiazolidines; Transferrin | 2000 |
Tissue-specific regulation of glutathione homeostasis and the activator protein-1 (AP-1) response in the rat conceptus.
Topics: Animals; Cytoprotection; DNA; Embryonic and Fetal Development; Female; Glutathione; Homeostasis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiazoles; Thiazolidines; Transcription Factor AP-1; Yolk Sac | 1999 |
Role of actin polymerization and actin cables in actin-patch movement in Schizosaccharomyces pombe.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Contractile Proteins; Cytoskeletal Proteins; Cytoskeleton; Fluorescent Dyes; Genes, Reporter; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Microfilament Proteins; Microscopy, Confocal; Microscopy, Video; Polymers; Profilins; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Thiazoles; Thiazolidines; Time Factors; Tropomyosin | 2001 |
Rop GTPase-dependent dynamics of tip-localized F-actin controls tip growth in pollen tubes.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Polarity; Cytoskeleton; Dose-Response Relationship, Drug; Gene Expression; GTPase-Activating Proteins; Mice; Models, Biological; Nicotiana; Plant Proteins; Plant Structures; Plants, Toxic; Pollen; Protein Structure, Tertiary; Recombinant Fusion Proteins; rho GTP-Binding Proteins; Talin; Thiazoles; Thiazolidines | 2001 |
An antiprion effect of the anticytoskeletal drug latrunculin A in yeast.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Fungal Proteins; Heat-Shock Proteins; Marine Toxins; Peptide Termination Factors; Prions; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2000 |
Enhanced potency of human Sonic hedgehog by hydrophobic modification.
Topics: Acyl Coenzyme A; Amides; Amino Acid Substitution; Animals; Cell Line; Circular Dichroism; Cysteine; Ethylmaleimide; Fatty Acids; Formaldehyde; Hedgehog Proteins; Humans; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; Iodoacetamide; Membrane Proteins; Mice; Mice, Inbred C3H; Patched Receptors; Peptide Fragments; Protein Binding; Protein Processing, Post-Translational; Proteins; Receptors, Cell Surface; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Trans-Activators; Up-Regulation | 2001 |
A role for actin, Cdc1p, and Myo2p in the inheritance of late Golgi elements in Saccharomyces cerevisiae.
Topics: Actins; Biomarkers; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Cycle Proteins; Drug Resistance, Microbial; Fungal Proteins; Golgi Apparatus; Green Fluorescent Proteins; Guanine Nucleotide Exchange Factors; Luminescent Proteins; Membrane Proteins; Mutagenesis; Myosin Heavy Chains; Myosin Type II; Myosin Type V; Myosins; Phenotype; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines; Transcription Factors | 2001 |
Restriction of secretory granule motion near the plasma membrane of chromaffin cells.
Topics: Actins; Animals; Atrial Natriuretic Factor; Botulinum Toxins, Type A; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin Cells; Cytoskeleton; Diffusion; Green Fluorescent Proteins; Humans; Luminescent Proteins; Membrane Proteins; Microscopy, Fluorescence; Nerve Tissue Proteins; R-SNARE Proteins; Recombinant Fusion Proteins; Secretory Vesicles; Synaptosomal-Associated Protein 25; Tetanus Toxin; Thiazoles; Thiazolidines; Time Factors | 2001 |
Platelet-activating factor antagonist, SM-12502, attenuates experimental glomerular thrombosis in rats.
Topics: Animals; Fibrin; Kidney Glomerulus; Lipopolysaccharides; Male; Neutrophil Activation; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Thrombosis | 2001 |
Role of the actin cytoskeleton in T cell absorption and internalization of ligands from APC.
Topics: Absorption; Actins; Animals; Antigen-Presenting Cells; Bridged Bicyclo Compounds, Heterocyclic; CD28 Antigens; Cells, Cultured; Cytoskeleton; Interphase; Ligands; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oligopeptides; Receptors, Antigen, T-Cell; T-Lymphocytes; Thiazoles; Thiazolidines | 2001 |
Carbon disulfide at a Chinese viscose factory external and internal exposure assessment.
Topics: Adult; Air Pollution, Indoor; Carbon Compounds, Inorganic; Cellulose; Chromatography, High Pressure Liquid; Circadian Rhythm; Humans; Industry; Male; Manufactured Materials; Occupational Exposure; Sulfides; Thiazoles; Thiazolidines; Time Factors | 2000 |
Microtubules are involved in glucose-dependent dissociation of the yeast vacuolar [H+]-ATPase in vivo.
Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; G2 Phase; Glucose; Microtubules; Nocodazole; Protein Conformation; Proton-Translocating ATPases; Saccharomyces cerevisiae; Temperature; Thiazoles; Thiazolidines; Vacuolar Proton-Translocating ATPases | 2001 |
cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Line; Cell Membrane Permeability; Cytoplasmic Vesicles; Cytoskeleton; Dogs; Fluorescent Dyes; Luminescent Proteins; Mutagenesis, Site-Directed; Neural Cell Adhesion Molecules; Protein Transport; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; trans-Golgi Network | 2001 |
Cell wall deposition during morphogenesis in fucoid algae.
Topics: Actins; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Polarity; Cell Wall; Cellulose; Cytoskeleton; Dimethyl Sulfoxide; Dinitrobenzenes; Fertilization; Golgi Apparatus; Herbicides; Morphogenesis; Osmotic Pressure; Phaeophyceae; Polysaccharides; Seawater; Sulfanilamides; Thiazoles; Thiazolidines; Zygote | 2001 |
Tumor necrosis factor-alpha inhibits store-mediated Ca2+ entry in the human hepatocellular carcinoma cell line HepG2.
Topics: Actins; Atrial Natriuretic Factor; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Carcinogens; Carcinoma, Hepatocellular; Cell Compartmentation; Cytochalasin D; Cytoskeleton; Humans; Liver Neoplasms; Nucleic Acid Synthesis Inhibitors; Polymers; ras Proteins; Thapsigargin; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Etk/Bmx activation modulates barrier function in epithelial cells.
Topics: Actins; Adaptation, Physiological; Animals; beta Catenin; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Fractionation; Cell Hypoxia; Cell Line; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Detergents; Electric Impedance; Epithelial Cells; Kidney; Membrane Proteins; Occludin; Parotid Gland; Phenotype; Protein-Tyrosine Kinases; Rats; Signal Transduction; Stress Fibers; Thiazoles; Thiazolidines; Trans-Activators | 2001 |
Sperm incorporation in Xenopus laevis: characterisation of morphological events and the role of microfilaments.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytoplasmic Granules; Depsipeptides; Female; Larva; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Ovum; Peptides, Cyclic; Sperm-Ovum Interactions; Spermatozoa; Thiazoles; Thiazolidines; Time Factors; Xenopus laevis | 2001 |
Fission yeast Aip3p (spAip3p) is required for an alternative actin-directed polarity program.
Topics: Actins; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Polarity; Fungal Proteins; Genes, Reporter; Microfilament Proteins; Microscopy, Fluorescence; Microtubules; Models, Molecular; Plasmids; Protein Binding; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines; Two-Hybrid System Techniques | 2001 |
Dynamics of immature secretory granules: role of cytoskeletal elements during transport, cortical restriction, and F-actin-dependent tethering.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Chromogranins; Furin; Green Fluorescent Proteins; Humans; Luminescent Proteins; Microscopy, Confocal; Microtubules; Models, Biological; Nocodazole; Organelles; PC12 Cells; Protein Transport; Rats; Recombinant Fusion Proteins; Secretory Vesicles; Subtilisins; Thiazoles; Thiazolidines; Transfection | 2001 |
X-ray photoelectron spectra of Pd(II) and Pt(II) complexes with 1,3-thiazolidine-2-thione. A quantum mechanics study on the free ligand.
Topics: Ligands; Palladium; Platinum; Quantum Theory; Spectrometry, X-Ray Emission; Stereoisomerism; Thermodynamics; Thiazoles; Thiazolidines | 2001 |
Oxidation of L-thiazolidine-4-carboxylate by delta1-pyrroline-5-carboxylate reductase in Escherichia coli.
Topics: Animals; Antioxidants; delta-1-Pyrroline-5-Carboxylate Reductase; Escherichia coli; Mice; Mutation; Oxidation-Reduction; Pyrroles; Pyrroline Carboxylate Reductases; Substrate Specificity; Thiazoles; Thiazolidines | 2001 |
[Reversion of cancer and mitochondrial filamentation].
Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Screening Assays, Antitumor; Mitochondria; Neoplasms; Rotenone; Thiazoles; Thiazolidines; Uncoupling Agents | 2000 |
Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Animals; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Crk-Associated Substrate Protein; Cytochalasin D; Cytoskeletal Proteins; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Immunoblotting; Indoles; Maleimides; Marine Toxins; Mice; Microscopy, Fluorescence; Myosin-Light-Chain Phosphatase; Nucleic Acid Synthesis Inhibitors; Oxazoles; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Thiazoles; Thiazolidines; Time Factors | 2001 |
The actin cytoskeleton is required for the trafficking of the B cell antigen receptor to the late endosomes.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Cross-Linking Reagents; Cytochalasin D; Cytoskeleton; Depsipeptides; Dose-Response Relationship, Drug; Endosomes; Humans; Hybridomas; Lymphocyte Activation; Lysosomes; Mice; Microscopy, Electron; Microscopy, Fluorescence; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; Phosphorylation; Protein Transport; Rats; Receptors, Antigen, B-Cell; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Tyrosine | 2001 |
Slow-binding inhibition of human prostaglandin endoperoxide synthase-2 with darbufelone, an isoform-selective antiinflammatory di-tert-butyl phenol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Enzyme Activation; Humans; Isoenzymes; Kinetics; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein Binding; Recombinant Proteins; Spectrophotometry; Thiazoles; Thiazolidines | 2001 |
Subcellular positioning of small molecules.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Cell Physiological Phenomena; Cytological Techniques; Cytoskeleton; Endothelium, Vascular; Mitochondria; Particle Size; Thiazoles; Thiazolidines | 2001 |
Spike-associated fast contraction of dendritic spines in cultured hippocampal neurons.
Topics: Actins; Action Potentials; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dendrites; Gene Expression; Green Fluorescent Proteins; Hippocampus; Indicators and Reagents; Luminescent Proteins; Neurons; Patch-Clamp Techniques; Rats; Thiazoles; Thiazolidines | 2001 |
Stages of synapse development defined by dependence on F-actin.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cells, Cultured; Extracellular Matrix; Fluorescent Dyes; Hippocampus; Nerve Tissue Proteins; Neurons; Rats; Synapses; Synaptic Vesicles; Synaptophysin; Thiazoles; Thiazolidines; Time Factors | 2001 |
G(alpha)11 signaling through ARF6 regulates F-actin mobilization and GLUT4 glucose transporter translocation to the plasma membrane.
Topics: Actins; Adenoviridae; Adipocytes; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Androstadienes; Animals; Antimetabolites; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Cells, Cultured; Deoxyglucose; Electroporation; Endothelin-1; Enzyme Inhibitors; Genes, Dominant; Glucose Transporter Type 4; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Insulin; Male; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Nocodazole; Phosphoinositide-3 Kinase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazoles; Thiazolidines; Wortmannin | 2001 |
Functionally distinct pools of actin in secretory cells.
Topics: Acids; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Gastric Mucosa; Homeostasis; In Vitro Techniques; Parietal Cells, Gastric; Rabbits; Stimulation, Chemical; Thiazoles; Thiazolidines | 2001 |
Effects of CP-060S, a novel cardioprotective drug, in the methacholine-induced ECG change model in rats.
Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Choline; Coronary Vessels; Diltiazem; Electrocardiography; Heart Rate; Infusions, Parenteral; Injections, Intravenous; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasodilator Agents | 2001 |
Thiazolidine prodrugs as protective agents against gamma-radiation-induced toxicity and mutagenesis in V79 cells.
Topics: Animals; Antimutagenic Agents; Cell Death; Cell Line; Cricetinae; Cricetulus; Cysteamine; Cysteine; Gamma Rays; Mercaptoethylamines; Mutagenicity Tests; Prodrugs; Radiation-Protective Agents; Structure-Activity Relationship; Sugar Alcohols; Thiazoles; Thiazolidines | 2001 |
Lilliputian mutant of maize lacks cell elongation and shows defects in organization of actin cytoskeleton.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Size; Cytoskeleton; Fluorescent Antibody Technique, Indirect; Microtubules; Mutation; Phenotype; Plant Roots; Thiazoles; Thiazolidines; Zea mays | 2001 |
Glutamate regulates actin-based motility in axonal filopodia.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Cell Differentiation; Cell Movement; Cells, Cultured; Central Nervous System; Glutamic Acid; Green Fluorescent Proteins; Growth Cones; Hippocampus; Immunohistochemistry; Luminescent Proteins; Neuronal Plasticity; Pseudopodia; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; tau Proteins; Thiazoles; Thiazolidines | 2001 |
Regulation of dendritic spine motility in cultured hippocampal neurons.
Topics: Action Potentials; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Surface Extensions; Cells, Cultured; Dendrites; Fluorescent Dyes; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Mice; Microscopy, Confocal; Neurons; Particle Size; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Synaptophysin; Temperature; Tetrodotoxin; Thiazoles; Thiazolidines; Time Factors | 2001 |
Disruption of the actin cytoskeleton regulates cytokine-induced iNOS expression.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Depsipeptides; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Genes, fos; Genes, Reporter; Glomerular Mesangium; Interleukin-1; Kinetics; Luciferases; Male; Marine Toxins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Serum Response Factor; Thiazoles; Thiazolidines; Transcription Factors; Transfection | 2001 |
Regulation of PGE(2) and PGI(2) release from human umbilical vein endothelial cells by actin cytoskeleton.
Topics: Actins; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Marine Toxins; Microtubules; Nocodazole; Thiazoles; Thiazolidines; Umbilical Veins | 2001 |
Bud8p and Bud9p, proteins that may mark the sites for bipolar budding in yeast.
Topics: Actins; Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Cell Fractionation; Cell Polarity; Fungal Proteins; Genes, Reporter; Immunoblotting; Membrane Glycoproteins; Membrane Proteins; Microscopy, Fluorescence; Molecular Sequence Data; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Thiazoles; Thiazolidines | 2001 |
Actin polymerization is essential for pollen tube growth.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Contractile Proteins; Cytochalasin D; Cytoplasmic Streaming; Deoxyribonuclease I; Dose-Response Relationship, Drug; Humans; Lilium; Microfilament Proteins; Nucleic Acid Synthesis Inhibitors; Plant Proteins; Plant Structures; Pollen; Polymers; Profilins; Thiazoles; Thiazolidines | 2001 |
Delta regulates keratinocyte spreading and motility independently of differentiation.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Adhesion; Cell Differentiation; Cell Membrane; Cell Movement; Cells, Cultured; Culture Media; Cytoskeleton; Drosophila Proteins; Genetic Vectors; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Membrane Proteins; Mutation; Pseudopodia; Receptors, Notch; Repressor Proteins; Signal Transduction; Thiazoles; Thiazolidines; Transfection | 2001 |
Entamoeba invadens: enhancement of excystation and metacystic development by cytochalasin D.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Depsipeptides; Entamoeba; Marine Toxins; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; Porifera; Thiazoles; Thiazolidines | 2001 |
Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2.
Topics: Actins; Apoptosis; bcl-2-Associated X Protein; Breast; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Line, Transformed; Cell Survival; Epithelial Cells; Female; Humans; Mitochondria; Neoplasm Metastasis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Transport; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Thiazolidines; Transfection; Tumor Cells, Cultured | 2001 |
A src family tyrosine kinase inhibits neurotransmitter release from neuronal cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Size; Cells, Cultured; Cerebellum; Cytoskeletal Proteins; Dopamine; Focal Adhesion Kinase 2; Gene Expression; Glutamic Acid; Humans; Neurons; Oncogene Protein pp60(v-src); Paxillin; PC12 Cells; Phalloidine; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; src-Family Kinases; Thiazoles; Thiazolidines; Tyrosine | 2001 |
Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling.
Topics: 3T3 Cells; Actins; Adipocytes; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Exfoliatins; Glucose; Glucose Transporter Type 4; Insulin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; rho GTP-Binding Proteins; Thiazoles; Thiazolidines | 2001 |
Caught in the actin.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Chromatids; Cytoskeleton; Mitosis; Schizosaccharomyces; Thiazoles; Thiazolidines | 2001 |
Actin microfilaments facilitate the retrograde transport from the Golgi complex to the endoplasmic reticulum in mammalian cells.
Topics: Actin Cytoskeleton; Actins; Animals; Biological Transport; Botulinum Toxins; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytochalasin D; Endoplasmic Reticulum; Golgi Apparatus; HeLa Cells; Humans; Intracellular Membranes; Mammals; Membrane Glycoproteins; Microtubules; Receptors, Peptide; Shiga Toxin; Thiazoles; Thiazolidines; Viral Envelope Proteins | 2001 |
Dynein binds to beta-catenin and may tether microtubules at adherens junctions.
Topics: Adherens Junctions; Antineoplastic Agents; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chromatography, Affinity; Cytoskeletal Proteins; Cytoskeleton; Dyneins; Epithelial Cells; Microscopy, Fluorescence; Microtubules; Nocodazole; Precipitin Tests; Protein Binding; Thiazoles; Thiazolidines; Trans-Activators | 2001 |
The cross-sectional study of the health effects of occupational exposure to carbon disulfide in a Chinese viscose plant.
Topics: Adult; Air Pollution, Indoor; Carbon Disulfide; Cellulose; Chromatography, Gas; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Environmental Monitoring; Humans; Kinetics; Male; Occupational Exposure; Occupational Health; Occupations; Risk Assessment; Solvents; Textile Industry; Thiazoles; Thiazolidines; Workplace | 2001 |
Intracellular magnetophoresis of statoliths in Chara rhizoids and analysis of cytoplasm viscoelasticity.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Chlorophyta; Cytoplasm; Cytoskeleton; Dinitrobenzenes; Dose-Response Relationship, Drug; Elasticity; Gravitation; Gravity Sensing; Herbicides; Hypergravity; Magnetics; Plastids; Sulfanilamides; Thiazoles; Thiazolidines; Viscosity | 2001 |
Synthesis and antiinflammatory, analgesic activity of 3,3'-(1,2-ethanediyl)-bis[2-aryl-4-thiazolidinone] chiral compounds. Part 10.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Magnetic Resonance Spectroscopy; Male; Mice; Rats; Rats, Wistar; Stereoisomerism; Thiazoles; Thiazolidines | 2001 |
Keratinocyte growth factor reduces alveolar epithelial susceptibility to in vitro mechanical deformation.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cell Survival; Cells, Cultured; Epithelial Cells; Extracellular Matrix; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Male; Microscopy, Fluorescence; Phenotype; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Stress, Mechanical; Thiazoles; Thiazolidines; Ventilators, Mechanical | 2001 |
Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes.
Topics: Actins; Adenoviridae; Adipocytes; Animals; Bacterial Proteins; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Genes, Reporter; Glucose Transporter Type 4; Glucosyltransferases; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Microinjections; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Nerve Tissue Proteins; Oocytes; Protein Transport; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Tissue Extracts; Transport Vesicles; Vanadates; Wiskott-Aldrich Syndrome Protein, Neuronal; Xenopus laevis | 2001 |
Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein.
Topics: Actins; Amino Acid Sequence; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Line; Cell Nucleus; Cytoplasm; Gene Expression; Green Fluorescent Proteins; Heat-Shock Response; Heating; Humans; Luminescent Proteins; Mice; Microfilament Proteins; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Muscle, Smooth; Mutagenesis; Myocardium; Nuclear Localization Signals; Protein Transport; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Stress, Physiological; Thiazoles; Thiazolidines | 2001 |
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, Differentiation; Antioxidants; Blood Glucose; Calcium; Cell Line; Cell Separation; Cysteine; Dimerization; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Glucose; Green Fluorescent Proteins; HeLa Cells; Humans; Hypoglycemic Agents; Immunohistochemistry; Islets of Langerhans; Luminescent Proteins; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Mutagenesis, Site-Directed; Mutation; NAD+ Nucleosidase; Oligonucleotides, Antisense; Pyrrolidonecarboxylic Acid; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transfection | 2002 |
Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cycloheximide; Fungal Proteins; HSP70 Heat-Shock Proteins; Microscopy, Electron; Mitochondria; Mutagenesis; Protein Denaturation; Protein Folding; Protein Synthesis Inhibitors; Protein Transport; Saccharomyces cerevisiae; Temperature; Thiazoles; Thiazolidines | 2001 |
Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells.
Topics: Actins; Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cell Polarity; Cytoskeleton; Dogs; Epithelial Cells; Green Fluorescent Proteins; Humans; Kidney; Luminescent Proteins; Macromolecular Substances; Microtubules; Mutagenesis, Site-Directed; Nocodazole; Protein Binding; Protein Transport; Rats; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Transfection | 2001 |
Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division.
Topics: Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Cytoskeletal Proteins; Cytoskeleton; Drosophila melanogaster; Drosophila Proteins; Epithelial Cells; In Situ Hybridization; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Mitosis; Molecular Sequence Data; Neurons; Neuropeptides; Recombinant Fusion Proteins; Spindle Apparatus; Thiazoles; Thiazolidines; Two-Hybrid System Techniques | 2001 |
Effects of the marine macrolides swinholide A and jasplakinolide on outflow facility in monkeys.
Topics: Animals; Anterior Chamber; Bridged Bicyclo Compounds, Heterocyclic; Depsipeptides; Dose-Response Relationship, Drug; Drug Combinations; Macaca fascicularis; Marine Toxins; Peptides, Cyclic; Thiazoles; Thiazolidines | 2001 |
Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy.
Topics: 3T3 Cells; Actins; Amides; Animals; Blotting, Northern; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; COS Cells; DNA-Binding Proteins; Enzyme Activation; GATA4 Transcription Factor; Hypertrophy; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Luciferases; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Myocardium; Phenylephrine; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Pyridines; Rats; rho-Associated Kinases; Thiazoles; Thiazolidines; Transcription Factors; Transcription, Genetic; Transfection; Zinc Fingers | 2002 |
Molecular ordering of the initial signaling events of CD95.
Topics: Actin Cytoskeleton; Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Animals; Anti-Bacterial Agents; Apoptosis; beta-Cyclodextrins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Cell Membrane; Cyclodextrins; Endocytosis; fas Receptor; Fas-Associated Death Domain Protein; Filipin; Fluorescent Dyes; Humans; Ionophores; Ligands; Lymphocytes; Membrane Microdomains; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; Models, Biological; Nystatin; Receptor Aggregation; Signal Transduction; Thiazoles; Thiazolidines | 2002 |
G2/M arrest caused by actin disruption is a manifestation of the cell size checkpoint in fission yeast.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Size; Fungal Proteins; G2 Phase; Mitosis; Phosphorylation; ras-GRF1; Schizosaccharomyces; Thiazoles; Thiazolidines; Time Factors | 2001 |
Cortical actin filaments potentially interact with cortical microtubules in regulating polarity of cell expansion in primary roots of maize (Zea mays L.).
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Immunohistochemistry; Microscopy, Confocal; Microtubules; Paclitaxel; Phalloidine; Plant Roots; Thiazoles; Thiazolidines; Zea mays | 2000 |
Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice.
Topics: Animals; Bradykinin; Cystathionine beta-Synthase; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione Peroxidase; Homocysteine; Hyperhomocysteinemia; Liver; Mesentery; Methacholine Chloride; Mice; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Vasodilation | 2002 |
Effects of the prolyl endopeptidase inhibitor S 17092 on cognitive deficits in chronic low dose MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition Disorders; Conditioning, Operant; Discrimination Learning; Dopamine Agents; Indoles; Macaca fascicularis; Male; Parkinson Disease, Secondary; Pattern Recognition, Visual; Prolyl Oligopeptidases; Psychomotor Performance; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles; Thiazolidines | 2002 |
In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knocko
Topics: Acetylcysteine; Animals; Apoptosis; Ascorbic Acid; Dexamethasone; gamma-Glutamyltransferase; Glutathione; Mice; Mice, Knockout; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thymus Gland | 2002 |
Polarization IR spectra of model crystals containing cyclic N-H...S bonded dimers: 2-mercaptothiazoline and 2-mercapto-1-methylimidazole.
Topics: Hydrogen Bonding; Imidazoles; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Thiazoles; Thiazolidines | 2002 |
Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Cell Polarity; Dogs; Endocytosis; Endosomes; Epithelial Cells; Fluorescent Antibody Technique; Intracellular Membranes; Kidney; Kinetics; Microscopy, Confocal; Models, Biological; Receptors, Cell Surface; Receptors, LDL; Receptors, Transferrin; Thiazoles; Thiazolidines; Tight Junctions; Transferrin | 2002 |
Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates.
Topics: Antigens, CD; Antigens, Surface; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cell Compartmentation; Cell Membrane; Cells, Cultured; Centrioles; Cytochalasin D; Cytoplasmic Granules; Endocytosis; Endosomes; Epidermal Cells; Fluorescent Antibody Technique; Humans; Kinetics; Langerhans Cells; Lectins, C-Type; Mannose-Binding Lectins; Microscopy, Confocal; Microscopy, Immunoelectron; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2002 |
L-2-Oxothiazolidine-4-carboxylate reverses the tumour growth-promoting effect of interleukin-2 and improves the anti-tumour efficacy of biochemotherapy in mice bearing B16 melanoma liver metastases.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Female; Glutathione; Interleukin-2; Liver; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured | 2002 |
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Protein Isoforms; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Type C Phospholipases | 2002 |
Retinoic acid exacerbates experimental radiation nephropathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Extracellular Matrix; Fibrosis; Hypertension, Renal; Kidney; Kidney Diseases; Kidney Failure, Chronic; Proteinuria; Pyridones; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Tretinoin; Uremia; Whole-Body Irradiation | 2002 |
G protein-coupled receptor/arrestin3 modulation of the endocytic machinery.
Topics: Adrenergic beta-Agonists; Animals; Arrestins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Chlorocebus aethiops; Coated Pits, Cell-Membrane; COS Cells; Endocytosis; GTP-Binding Proteins; Humans; Image Processing, Computer-Assisted; Isoproterenol; Receptor, Muscarinic M1; Receptors, Adrenergic, beta-2; Receptors, Cell Surface; Receptors, Muscarinic; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2002 |
Bifunctional derivative of p,p'-dichlorochalcone. Part III. Synthesis and study for cytotoxic activity of a new compound, 2-[2,2-bis(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-thiazolidin-4-one from p,p'-dichlorochalcone.
Topics: Antineoplastic Agents; Chalcone; Chalcones; Chlorobenzenes; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2002 |
Disruption of the actin cytoskeleton results in the promotion of gravitropism in inflorescence stems and hypocotyls of Arabidopsis.
Topics: Actin Cytoskeleton; Actins; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Fluorescent Dyes; Gravitropism; Hydrazines; Hypocotyl; Microscopy, Confocal; Phalloidine; Plant Roots; Plant Stems; Signal Transduction; Thiazoles; Thiazolidines | 2002 |
Localization of transcripts of the zebrafish morphogen Squint is dependent on egg activation and the microtubule cytoskeleton.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Gene Expression Regulation, Developmental; In Situ Hybridization; Microscopy, Fluorescence; Microtubules; Nodal Signaling Ligands; Ovum; RNA; Thiazoles; Thiazolidines; Transforming Growth Factor beta; Zebrafish; Zebrafish Proteins | 2002 |
Pictures in cell biology. Actin-driven polar growth of plant cells.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Polarity; Contractile Proteins; Cyclic AMP; Destrin; Microfilament Proteins; Plant Roots; Pollen; Profilins; Thiazoles; Thiazolidines | 2002 |
The involvement of lipid rafts in the regulation of integrin function.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Cell Adhesion; Cell Membrane; Cholesterol; Cytochalasin D; Cytoskeleton; Humans; Integrin alpha4beta1; Integrins; Lymphocyte Function-Associated Antigen-1; Magnesium; Membrane Lipids; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Binding; Protein Isoforms; Receptors, Lymphocyte Homing; Signal Transduction; T-Lymphocytes; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2002 |
Actin cytoskeletal modulation of pressure-induced depolarization and Ca(2+) influx in cerebral arteries.
Topics: Actins; Androstadienes; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cerebral Arteries; Cytochalasin D; Cytoskeleton; Egtazic Acid; Endothelium, Vascular; In Vitro Techniques; Ionomycin; Male; Marine Toxins; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Nigericin; Rats; Rats, Inbred WKY; Thiazoles; Thiazolidines; Vasoconstriction; Wortmannin | 2002 |
Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function.
Topics: Actins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Myosin Light Chains; Oligonucleotides, Antisense; Phosphorylation; Polymers; Protein-Tyrosine Kinases; Pulmonary Artery; Thiazoles; Thiazolidines; Thrombin | 2002 |
The long-lasting anti-anginal effects of CP-060S in a rat model of arginine vasopressin-induced myocardial ischaemia.
Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Diltiazem; Hemodynamics; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Vasoconstrictor Agents | 2002 |
Endoplasmic reticulum dynamics, inheritance, and cytoskeletal interactions in budding yeast.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cytoskeleton; Dimethyl Sulfoxide; Endoplasmic Reticulum; Fungal Proteins; Genes, Reporter; Heat-Shock Proteins; Intracellular Membranes; Membrane Proteins; Membrane Transport Proteins; Microtubules; Models, Biological; Nuclear Envelope; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Solvents; Thiazoles; Thiazolidines | 2002 |
Wound closure in the lamellipodia of single cells: mediation by actin polymerization in the absence of an actomyosin purse string.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytochalasin D; Enzyme Inhibitors; Humans; Microscopy, Video; Myosin Type II; Nucleic Acid Synthesis Inhibitors; Phalloidine; Pseudopodia; Sea Urchins; Staurosporine; Thiazoles; Thiazolidines | 2002 |
Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Animals; Blood Glucose; Body Weight; Dipeptidyl Peptidase 4; Drinking Behavior; Glucose; Glucose Tolerance Test; Glycogen Synthase; Hyperinsulinism; Insulin; Islets of Langerhans; Male; Muscle, Skeletal; Pentanoic Acids; Protease Inhibitors; Rats; Rats, Zucker; Reference Values; Thiazoles; Thiazolidines; Time Factors | 2002 |
Cytoskeletal responses during early development of the downy mildew of grapevine (Plasmopara viticola).
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carbamates; Cell Polarity; Cytoplasmic Vesicles; Cytoskeleton; Oomycetes; Spores, Fungal; Thiazoles; Thiazolidines; Time Factors; Tubulin; Vitis | 2002 |
Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cytoskeletal Proteins; DNA-Binding Proteins; Endocytosis; Energy Transfer; Genes, Reporter; Microscopy, Fluorescence; Models, Biological; Pheromones; Protein Binding; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines; Transcription Factors | 2002 |
Transcriptional regulation of a contractile gene by mechanical forces applied through integrins in osteoblasts.
Topics: Actins; Animals; beta-Galactosidase; Binding, Competitive; Blotting, Northern; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Chickens; Cytochalasin D; Gene Deletion; Green Fluorescent Proteins; Immunoblotting; Luminescent Proteins; Microscopy, Fluorescence; Muscle, Smooth; Mutation; Osteoblasts; Phenotype; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Rats; Reactive Oxygen Species; RNA, Messenger; Stress, Mechanical; Thiazoles; Thiazolidines; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolae; Caveolin 1; Caveolins; Cell Line; Cholesterol; Depsipeptides; Dynamins; Endocytosis; GTP Phosphohydrolases; Haplorhini; Peptides, Cyclic; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Simian virus 40; Stress Fibers; Thiazoles; Thiazolidines; Transport Vesicles | 2002 |
Visualization of peroxisomes in living plant cells reveals acto-myosin-dependent cytoplasmic streaming and peroxisome budding.
Topics: Actin Cytoskeleton; Actins; Arabidopsis; Benzamides; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cytoplasmic Streaming; Diacetyl; Green Fluorescent Proteins; Hypocotyl; Luminescent Proteins; Microscopy, Confocal; Microscopy, Immunoelectron; Microtubules; Myosins; Nocodazole; Peroxisome-Targeting Signal 1 Receptor; Peroxisomes; Plant Roots; Plants, Genetically Modified; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Talin; Thiazoles; Thiazolidines | 2002 |
The amount of thiolic antioxidant ingestion needed to improve several immune functions is higher in aged than in adult mice.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Cell Adhesion; Chemotaxis, Leukocyte; Diet; Dose-Response Relationship, Drug; Female; Leukocytes; Lymphocytes; Mice; Phagocytosis; Sulfhydryl Compounds; Superoxides; Thiazoles; Thiazolidines | 2002 |
Watasemycins A and B, new antibiotics produced by Streptomyces sp. TP-A0597.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Seawater; Streptomyces; Thiazoles; Thiazolidines; Yeasts | 2002 |
Novel dipeptide macrocycles from 4-oxo, -thio, and -amino-substituted proline derivatives.
Topics: Cyclization; Dipeptides; Drug Design; Proline; Thiazoles; Thiazolidines | 2002 |
Caveolin-associated filamentous actin (Cav-actin) defines a novel F-actin structure in adipocytes.
Topics: 3T3 Cells; Actins; Adipocytes; Animals; Bacterial Proteins; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Caveolins; Cell Differentiation; Cytoskeleton; Fibroblasts; Indicators and Reagents; Mice; Phalloidine; Rhodamines; Thiazoles; Thiazolidines | 2002 |
Native and cloned 5-HT(3A)(S) receptors are anchored to F-actin in clonal cells and neurons.
Topics: Actins; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Central Nervous System; CHO Cells; Clone Cells; Cloning, Molecular; COS Cells; Cricetinae; Culture Media, Serum-Free; Cytoskeleton; Fetus; Gene Expression Regulation; Hippocampus; Macromolecular Substances; Molecular Conformation; Neurons; Polymers; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Synaptic Transmission; Thiazoles; Thiazolidines; Transfection | 2002 |
Phospholipids undergo hop diffusion in compartmentalized cell membrane.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Compartmentation; Cell Line; Cell Membrane; Depsipeptides; Diffusion; Fibroblasts; Gold Colloid; Kidney; Marine Toxins; Models, Biological; Peptides, Cyclic; Phospholipids; Rats; Receptors, Transferrin; Thiazoles; Thiazolidines; Time Factors; Trypsin | 2002 |
Looking over the edge: a new role for Ena/VASP proteins in lamellipodial dynamics.
Topics: Actin Depolymerizing Factors; Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cytochalasin D; Cytoskeletal Proteins; Destrin; DNA-Binding Proteins; Listeria; Marine Toxins; Microfilament Proteins; Mutation; Nucleic Acid Synthesis Inhibitors; Phosphoproteins; Pseudopodia; Thiazoles; Thiazolidines | 2002 |
Toward computing relative configurations: 16-epi-latrunculin B, a new stereoisomer of the actin polymerization inhibitor latrunculin B.
Topics: Actins; Animals; Antineoplastic Agents; Antiviral Agents; Bridged Bicyclo Compounds, Heterocyclic; Herpesvirus 1, Human; Mice; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Porifera; Stereoisomerism; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2002 |
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Polarity; Chemotaxis; Depsipeptides; Dictyostelium; Enzyme Inhibitors; Feedback, Physiological; HL-60 Cells; Humans; Marine Toxins; Neutrophils; Peptides, Cyclic; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Pseudopodia; Thiazoles; Thiazolidines | 2002 |
The cytoskeleton and the secretory pathway are not involved in targeting the cowpea mosaic virus movement protein to the cell periphery.
Topics: Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Comovirus; Cytoskeleton; Dinitrobenzenes; Fabaceae; Golgi Apparatus; Green Fluorescent Proteins; Herbicides; Luminescent Proteins; Plant Viral Movement Proteins; Protoplasts; Secretory Vesicles; Sulfanilamides; Thiazoles; Thiazolidines; Transfection; Viral Proteins | 2002 |
Activation of oocytes by latrunculin A.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cells, Cultured; Fertilization; Kinetics; Oocytes; Starfish; Thiazoles; Thiazolidines | 2002 |
Induction of sperm maturation in vitro in epididymal cell cultures of the tammar wallaby (Macropus eugenii): disruption of motility initiation and sperm morphogenesis by inhibition of actin polymerization.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cells, Cultured; Coculture Techniques; Epididymis; Epithelial Cells; Fluorescent Antibody Technique; Macropodidae; Male; Polymers; Sperm Maturation; Sperm Motility; Spermatozoa; Thiazoles; Thiazolidines | 2002 |
Involvement of the mitogen-activated protein kinase SIMK in regulation of root hair tip growth.
Topics: Actin Cytoskeleton; Actins; Active Transport, Cell Nucleus; Bridged Bicyclo Compounds, Heterocyclic; Butadienes; Cell Nucleus; Cell Polarity; Cell Surface Extensions; Cytoplasm; Depsipeptides; Enzyme Activation; MAP Kinase Signaling System; Medicago sativa; Microscopy, Video; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nicotiana; Nitriles; Peptides, Cyclic; Plant Proteins; Plant Roots; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2002 |
Ca(2+) removal mechanisms in freshly isolated rabbit aortic endothelial cells.
Topics: Acetylcholine; Animals; Aorta; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Chelating Agents; Cytochalasin D; Cytoskeleton; Endoplasmic Reticulum; Endothelium, Vascular; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Nucleic Acid Synthesis Inhibitors; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium; Sodium-Calcium Exchanger; Thiazoles; Thiazolidines; Vasodilator Agents | 2002 |
An unexplained sequestration of latrunculin A is required in neutrophils for inhibition of actin polymerization.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Count; Chemotaxis; Culture Media; Destrin; Leukocyte Migration-Inhibitory Factors; Microfilament Proteins; Neutrophils; Rabbits; Thiazoles; Thiazolidines; Time Factors | 2002 |
Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha.
Topics: Actins; Animals; Apoptosis; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Death; Cell Membrane; Cholesterol; Cyclosporine; Cytoskeleton; Endosomes; Enzyme Inhibitors; Filipin; Gangliosides; Golgi Apparatus; Hepatocytes; Humans; Kinetics; Microscopy, Confocal; Microscopy, Immunoelectron; Mitochondria; Protein Binding; rab GTP-Binding Proteins; rab5 GTP-Binding Proteins; rab7 GTP-Binding Proteins; Rats; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs.
Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Antagonism; Glyburide; Guinea Pigs; Male; Naloxone; Pinacidil; Potassium Channels; Thiazoles; Thiazolidines | 2002 |
Modeling and biological evaluation of 3,3'-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor.
Topics: Animals; Carrageenan; Cyclooxygenase Inhibitors; Humans; Male; Pleurisy; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2002 |
Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.
Topics: 3T3 Cells; Actins; Adipocytes; Amino Acid Motifs; Animals; Bacterial Proteins; Bacterial Toxins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Nucleus; CHO Cells; Coatomer Protein; Cricetinae; Cytoplasmic Vesicles; Enzyme Activation; Golgi Apparatus; Mice; Microinjections; Microscopy, Confocal; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oocytes; rho GTP-Binding Proteins; Thiazoles; Thiazolidines; Time Factors; Wiskott-Aldrich Syndrome Protein, Neuronal; Xenopus laevis | 2002 |
The Rho-GAP Bem2p plays a GAP-independent role in the morphogenesis checkpoint.
Topics: Amino Acid Sequence; Base Sequence; Bridged Bicyclo Compounds, Heterocyclic; CDC28 Protein Kinase, S cerevisiae; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Cycle Proteins; Cell Polarity; Fungal Proteins; G2 Phase; Genes, cdc; Genes, Fungal; GTPase-Activating Proteins; MAP Kinase Signaling System; Metaphase; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Morphogenesis; Phosphorylation; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; ras-GRF1; Reproduction, Asexual; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines | 2002 |
Role of the actin cytoskeleton in store-mediated calcium entry in glioma C6 cells.
Topics: Actins; Adenosine Diphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Chelating Agents; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Glioma; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Rats; Thapsigargin; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Uridine Triphosphate | 2002 |
Micromechanical coupling between cell surface receptors and RGD peptides.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cytoskeleton; HeLa Cells; Humans; Kinetics; Oligopeptides; Receptors, Cell Surface; Stress, Mechanical; Thiazoles; Thiazolidines | 2002 |
Remodeling of organelle-bound actin is required for yeast vacuole fusion.
Topics: Actins; Adaptor Proteins, Signal Transducing; Antibodies; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cytoskeletal Proteins; Depsipeptides; Fungal Proteins; Ligands; Membrane Fusion; Membrane Microdomains; Mutation; Peptides, Cyclic; Protein Binding; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Trans-Activators; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins; Vacuoles; Wiskott-Aldrich Syndrome Protein; Yeasts | 2002 |
The MEK kinase Ssk2p promotes actin cytoskeleton recovery after osmotic stress.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cytoskeleton; Fluorescent Dyes; Genes, Fungal; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Osmotic Pressure; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sodium Chloride; Thiazoles; Thiazolidines; Two-Hybrid System Techniques | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
Alcohol and urinary 2-thiothiazolidine-4-carboxylic acid.
Topics: Adult; Alcohol Drinking; Carbon Disulfide; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Environmental Monitoring; Humans; Inhalation Exposure; Male; Occupational Exposure; Surveys and Questionnaires; Thiazoles; Thiazolidines | 2002 |
Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study.
Topics: Adipocytes; Animals; Diabetes Mellitus; Dipeptidyl Peptidase 4; Drug Administration Schedule; Enzyme Inhibitors; Glucose Clamp Technique; Glucose Tolerance Test; Insulin; Lipolysis; Liver; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Thiazoles; Thiazolidines | 2002 |
Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro.
Topics: Analysis of Variance; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Culture Techniques; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Free Radical Scavengers; Glutathione; Humans; Nicotine; Nicotinic Agonists; Periodontal Ligament; Protective Agents; Protein Biosynthesis; Proteins; Pyrrolidonecarboxylic Acid; Smoking; Statistics as Topic; Sulfhydryl Compounds; Superoxide Dismutase; Thiazoles; Thiazolidines | 2002 |
Structural determination and odor characterization of N-(2-mercaptoethyl)-1,3-thiazolidine, a new intense popcorn-like-smelling odorant.
Topics: Cysteamine; Fructose; Gas Chromatography-Mass Spectrometry; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Structure; Odorants; Smell; Thiazoles; Thiazolidines; Water; Zea mays | 2002 |
In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR.
Topics: Animals; Carbon Isotopes; Female; Glutathione; Glycine; Liver; Magnetic Resonance Spectroscopy; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2002 |
Localised depletion of polymerised actin at the front of Walker carcinosarcoma cells increases the speed of locomotion.
Topics: Actinin; Actins; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma 256, Walker; Cell Membrane; Cell Movement; Cell Polarity; Cell Size; Cell Surface Extensions; Colchicine; Diacetyl; Enzyme Inhibitors; Humans; Myosins; Pyridines; Thiazoles; Thiazolidines | 2002 |
Reorganization and translocation of the ectoplasmic cytoskeleton in the leech zygote by condensation of cytasters and interactions of dynamic microtubules and actin filaments.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Colchicine; Cytoskeleton; Fluorescent Dyes; Interphase; Leeches; Microinjections; Microscopy, Video; Microtubules; Paclitaxel; Phalloidine; Protein Transport; Thiazoles; Thiazolidines; Time Factors; Zygote | 2002 |
A Crk-II/TC10 signaling pathway is required for osmotic shock-stimulated glucose transport.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Deoxyglucose; Depsipeptides; Electrophoresis, Polyacrylamide Gel; Glucose; Glucose Transporter Type 4; Isoenzymes; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Osmosis; Osmotic Pressure; Peptides, Cyclic; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Precipitin Tests; Protein Binding; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; rho GTP-Binding Proteins; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Type C Phospholipases; Tyrosine | 2002 |
Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cytoskeletal Proteins; Cytoskeleton; Endocytosis; Endosomal Sorting Complexes Required for Transport; Fungal Proteins; Genetic Vectors; Ligases; Mutagenesis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Subcellular Fractions; Thiazoles; Thiazolidines; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases | 2002 |
Identification of a role for actin in translational fidelity in yeast.
Topics: Actins; Alleles; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytoskeleton; Models, Molecular; Mutation; Open Reading Frames; Peptide Elongation Factor 1; Phenotype; Protein Biosynthesis; Protein Conformation; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Suppression, Genetic; Thiazoles; Thiazolidines | 2002 |
Involvement of calcium signaling and the actin cytoskeleton in the membrane block to polyspermy in mouse eggs.
Topics: Acrosome; Acrosome Reaction; Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcimycin; Calcium; Cytochalasin B; Cytochalasin D; Cytoskeleton; Depsipeptides; Exocytosis; Female; Fertilization in Vitro; Male; Mice; Oocytes; Peptides, Cyclic; Signal Transduction; Sperm Motility; Spermatozoa; Thiazoles; Thiazolidines | 2002 |
Roles of the cytoskeleton and of protein phosphorylation events in the osmotic stress response in eel intestinal epithelium.
Topics: Actins; Alkaloids; Anguilla; Animals; Azepines; Benzophenanthridines; Bridged Bicyclo Compounds, Heterocyclic; Bumetanide; Cell Size; Colchicine; Cytochalasins; Cytoskeleton; Enzyme Inhibitors; Hypertonic Solutions; Hypotonic Solutions; Intestinal Mucosa; Ion Transport; Isoquinolines; Marine Toxins; Microtubules; Naphthalenes; Osmotic Pressure; Oxazoles; Phenanthridines; Phosphorylation; Protein Serine-Threonine Kinases; Sulfonamides; Thiazoles; Thiazolidines | 2002 |
Glycoprotein Ib cross-linking/ligation on echicetin-coated surfaces or echicetin-IgMkappa in stirred suspension activates platelets by cytoskeleton modulated calcium release.
Topics: Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Carrier Proteins; Cell Adhesion; Cytochalasin D; Cytoskeleton; Humans; Immunoglobulin M; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Nitric Oxide; Oxazoles; Phosphorylation; Platelet Activation; Platelet Glycoprotein GPIb-IX Complex; Proteins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidines; Tyrosine; Viper Venoms; von Willebrand Factor | 2002 |
Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Chromans; Dinoprostone; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Immunohistochemistry; Ligands; Male; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Testicular Neoplasms; Testis; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
Latrunculin and cytochalasin decrease chondrocyte matrix retention.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cartilage, Articular; Cattle; Cell Survival; Cells, Cultured; Chondrocytes; Cytochalasin B; Cytoskeleton; Detergents; Extracellular Matrix; Flow Cytometry; Hyaluronan Receptors; Hyaluronic Acid; In Vitro Techniques; Protein Binding; Solubility; Thiazoles; Thiazolidines | 2002 |
A diet supplemented with thiolic anti-oxidants improves leucocyte function in two strains of prematurely ageing mice.
Topics: Acetylcysteine; Aging, Premature; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Female; Leukocytes; Mice; Mice, Inbred BALB C; Species Specificity; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 2002 |
Contribution of F-actin to barrier properties of the blood-joint pathway.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Cytochalasin D; Endothelium, Vascular; Evans Blue; Extracellular Space; Knee Joint; Microcirculation; Rabbits; Synovial Fluid; Synovial Membrane; Thiazoles; Thiazolidines | 2002 |
Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolae; Caveolin 1; Caveolins; Cell Membrane; Centrosome; CHO Cells; Cricetinae; Endocytosis; Endosomes; Eukaryotic Cells; Green Fluorescent Proteins; Intracellular Membranes; Luminescent Proteins; Microscopy, Electron; Microscopy, Video; Microtubules; Models, Biological; Protein Transport; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2002 |
Endosome fusion and microtubule-based dynamics in the early endocytic pathway of dictyostelium.
Topics: Actins; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Dextrans; Dictyostelium; Endocytosis; Endosomes; Green Fluorescent Proteins; Horseradish Peroxidase; Kinetics; Luminescent Proteins; Membrane Fusion; Microtubules; Nocodazole; Pinocytosis; Protein Synthesis Inhibitors; Thiazoles; Thiazolidines; Tubulin | 2002 |
Stability of actin cytoskeleton and PKC-delta binding to actin regulate NKCC1 function in airway epithelial cells.
Topics: Acetophenones; Actin Cytoskeleton; Adrenergic alpha-Agonists; Animals; Benzopyrans; Bridged Bicyclo Compounds, Heterocyclic; Bumetanide; Cell Compartmentation; Cell Membrane; Cells, Cultured; Cytosol; Depsipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Humans; Immunohistochemistry; Isoenzymes; Methoxamine; Peptides, Cyclic; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Respiratory Mucosa; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Thiazoles; Thiazolidines | 2003 |
Regulation of phospholipase D activity by actin. Actin exerts bidirectional modulation of Mammalian phospholipase D activity in a polymerization-dependent, isoform-specific manner.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytosol; Deoxyribonuclease I; Depsipeptides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Macromolecular Substances; Magnesium Chloride; Mammals; Marine Toxins; Peptides, Cyclic; Phalloidine; Phospholipase D; Protein Isoforms; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; U937 Cells | 2002 |
High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Biomarkers; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cathepsin D; Cell Membrane; Dictyostelium; Endocytosis; Fluorescent Dyes; Karyopherins; Lipid Metabolism; Lipids; Membrane Proteins; Microfilament Proteins; Phagosomes; Proteins; Qb-SNARE Proteins; R-SNARE Proteins; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; SNARE Proteins; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2002 |
Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae.
Topics: Actins; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cytoskeletal Proteins; Cytoskeleton; Endocytosis; Fluorescent Dyes; Genotype; Humans; Microfilament Proteins; Molecular Sequence Data; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; src Homology Domains; Thiazoles; Thiazolidines; Two-Hybrid System Techniques; Wiskott-Aldrich Syndrome Protein | 2002 |
Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Cytoskeletal Proteins; Cytoskeleton; Genes, Fungal; Genes, Reporter; Macromolecular Substances; Microfilament Proteins; Myosin Type I; Polymers; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Two-Hybrid System Techniques; Wiskott-Aldrich Syndrome Protein | 2002 |
The vesicular transport protein Cgp1p/Vps54p/Tcs3p/Luv1p is required for the integrity of the actin cytoskeleton.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Wall; Cytoskeleton; Fungal Proteins; Membrane Proteins; Mutation; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Two-Hybrid System Techniques; Vesicular Transport Proteins; Yeasts | 2002 |
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
Topics: Antioxidants; Aorta; Ascorbic Acid; Endothelium, Vascular; Glutathione; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thioctic Acid | 2002 |
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China.
Topics: Adult; Carboxylic Acids; China; Diet; Diethylnitrosamine; Dimethylnitrosamine; Esophageal Neoplasms; Humans; Inositol Phosphates; Male; Middle Aged; N-Nitrosopyrrolidine; Nitrosamines; Nitroso Compounds; Thiazoles; Thiazolidines | 2002 |
Reversible protein phosphorylation regulates the dynamic organization of the pollen tube cytoskeleton: effects of calyculin A and okadaic acid.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Cell Polarity; Cytoskeleton; Enzyme Inhibitors; Fertilization; Flowers; Gene Expression Regulation, Plant; Lilium; Marine Toxins; Microtubules; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Plant Proteins; Thiazoles; Thiazolidines | 2002 |
Plasmalemmal voltage-activated K(+) currents in protoplasts from tobacco BY-2 cells: possible regulation by actin microfilaments?
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cations, Monovalent; Cell Membrane; Cells, Cultured; Cytochalasin B; Dinitrobenzenes; Membrane Potentials; Nicotiana; Paclitaxel; Potassium; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protoplasts; Rhodamines; Sulfanilamides; Thiazoles; Thiazolidines | 2002 |
Vacuole formation in mast cells responding to osmotic stress and to F-actin disassembly.
Topics: Actins; Amiloride; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Size; Enzyme Inhibitors; Hypertonic Solutions; Male; Mast Cells; Osmotic Pressure; Polymers; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Surface Tension; Thiazoles; Thiazolidines; Vacuoles; Water-Electrolyte Balance | 2002 |
Cytoskeleton interactions involved in the assembly and function of glycoprotein-80 adhesion complexes in dictyostelium.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Adhesion; Cell Communication; Cytoskeleton; Detergents; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Enterobacter aerogenes; Lipid Metabolism; Membrane Glycoproteins; Microfilament Proteins; Microscopy, Fluorescence; Octoxynol; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Thiazoles; Thiazolidines | 2003 |
Evidence for secretion-like coupling involving pp60src in the activation and maintenance of store-mediated Ca2+ entry in mouse pancreatic acinar cells.
Topics: Actins; Animals; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cytochalasin D; Cytoskeleton; Depsipeptides; Ion Transport; Male; Mice; Pancreas; Peptides, Cyclic; Proto-Oncogene Proteins pp60(c-src); Spectrometry, Fluorescence; Thapsigargin; Thiazoles; Thiazolidines | 2003 |
Three-dimensional common-feature hypotheses of inhibitors of calling behaviour and in vitro [14C]acetate incorporation by pheromone glands of Plodia interpunctella.
Topics: Acetates; Aniline Compounds; Animals; Behavior, Animal; Carbon Radioisotopes; Female; Larva; Lepidoptera; Male; Models, Molecular; Molecular Structure; Octopamine; Oxazoles; Pheromones; Pupa; Thiazoles; Thiazolidines | 2002 |
Glutamate-induced delta-catenin redistribution and dissociation from postsynaptic receptor complexes.
Topics: Actin Cytoskeleton; Animals; Armadillo Domain Proteins; Bridged Bicyclo Compounds, Heterocyclic; Catenins; Cell Adhesion Molecules; Cell Differentiation; Cells, Cultured; Cytoskeletal Proteins; Delta Catenin; Dendrites; Disks Large Homolog 4 Protein; Down-Regulation; Excitatory Amino Acid Antagonists; Female; Fetus; Fluorescent Antibody Technique; Glutamic Acid; Guanylate Kinases; Hippocampus; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Nerve Tissue Proteins; Phosphoproteins; Pregnancy; Rats; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Membranes; Synaptic Transmission; Thiazoles; Thiazolidines | 2002 |
Mechanisms of cell positioning during C. elegans gastrulation.
Topics: Actin Cytoskeleton; Actins; Animals; Body Patterning; Bridged Bicyclo Compounds, Heterocyclic; Caenorhabditis elegans; Cell Lineage; Cell Polarity; Chemotaxis; Cytochalasin D; Enzyme Inhibitors; Gastrula; Luminescent Proteins; Models, Biological; Morphogenesis; Nocodazole; Nucleic Acid Synthesis Inhibitors; Paclitaxel; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2003 |
Hyphal tip-associated localization of Cdc42 is F-actin dependent in Candida albicans.
Topics: Actins; Blotting, Northern; Bridged Bicyclo Compounds, Heterocyclic; Candida albicans; cdc42 GTP-Binding Protein; Cell Cycle; Cytoskeleton; DNA Primers; Genes, Fungal; Green Fluorescent Proteins; Hyphae; Luminescent Proteins; Marine Toxins; Models, Genetic; Plasmids; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transcription, Genetic | 2002 |
Decreased actin solubility observed during ATP-depletion is mimicked by severing agents but not depolymerizing agents in isolated and cultured proximal tubular cells.
Topics: Actins; Adenosine Triphosphate; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Depsipeptides; Female; Kidney Tubules, Proximal; LLC-PK1 Cells; Marine Toxins; Microscopy, Fluorescence; Peptides, Cyclic; Polymers; Rabbits; Solubility; Swine; Thiazoles; Thiazolidines | 2002 |
Centrosome separation: respective role of microtubules and actin filaments.
Topics: Actin Cytoskeleton; Anaphase; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Centrosome; Eukaryotic Cells; G2 Phase; Metaphase; Microtubules; Mitosis; Nocodazole; Prophase; Spindle Apparatus; Thiazoles; Thiazolidines; Xenopus laevis | 2002 |
Control of Lte1 localization by cell polarity determinants and Cdc14.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Caenorhabditis elegans Proteins; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Cycle Proteins; Cell Polarity; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Fungal Proteins; Gene Expression Regulation, Fungal; Guanine Nucleotide Exchange Factors; Microtubules; Mitosis; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Protein Tyrosine Phosphatases; Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2002 |
Unstable F-actin specifies the area and microtubule direction of cell expansion in Arabidopsis root hairs.
Topics: Actins; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytochalasin D; Cytoskeleton; Dinitrobenzenes; Dose-Response Relationship, Drug; Microtubules; Nucleic Acid Synthesis Inhibitors; Plant Roots; Sulfanilamides; Thiazoles; Thiazolidines | 2003 |
Actin-ATP hydrolysis is a major energy drain for neurons.
Topics: Actin Cytoskeleton; Actins; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Hypoxia; Cells, Cultured; Chick Embryo; Depsipeptides; Energy Metabolism; Enzyme Inhibitors; Hydrolysis; Neurons; Ouabain; Peptides, Cyclic; Sodium; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidines | 2003 |
Disruption of F-actin stimulates hypertonic activation of the BGT1 transporter in MDCK cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Line; Cell Membrane; Cytochalasin D; Dogs; GABA Plasma Membrane Transport Proteins; Hypertonic Solutions; Nucleic Acid Synthesis Inhibitors; Thiazoles; Thiazolidines; Tissue Distribution; Up-Regulation | 2003 |
Actin has a molecular scaffolding, not propulsive, role in presynaptic function.
Topics: Actins; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Depsipeptides; Hippocampus; Kinetics; Organ Culture Techniques; Peptides, Cyclic; Presynaptic Terminals; Protein Transport; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines | 2003 |
The interrelationships of actin and hyphal tip growth in the ascomycete Geotrichum candidum.
Topics: Actins; Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytoskeletal Proteins; Geotrichum; Hyphae; Microtubules; Molecular Sequence Data; Morphogenesis; Sequence Homology, Amino Acid; Staining and Labeling; Thiazoles; Thiazolidines | 2003 |
Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex.
Topics: Actins; Animals; Antigens, Surface; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Cells, Cultured; Cytoplasmic Granules; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Proteins; Nerve Tissue Proteins; Perfusion; Precipitin Tests; R-SNARE Proteins; Rats; SNARE Proteins; Synaptosomal-Associated Protein 25; Syntaxin 1; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2003 |
Establishment of latrunculin-A resistance in HeLa cells by expression of R183A D184A mutant beta-actin.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Drug Resistance, Neoplasm; HeLa Cells; Humans; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidines | 2003 |
Induction of c-fos expression by nicotine in human periodontal ligament fibroblasts is related to cellular thiol levels.
Topics: Analysis of Variance; Buthionine Sulfoximine; Cell Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Genes, fos; Glutathione; Humans; Nicotine; Periodontal Ligament; Protein Precursors; Pyrrolidonecarboxylic Acid; RNA, Messenger; Signal Transduction; Smoking; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors; Transcription, Genetic | 2003 |
Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells.
Topics: Actin Depolymerizing Factors; Actins; Active Transport, Cell Nucleus; Adenosine Triphosphate; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Nucleus; Cells, Cultured; Flow Cytometry; Fluorescent Dyes; Marine Toxins; Mast Cells; Microfilament Proteins; Microscopy, Confocal; Phalloidine; Protein Conformation; Rats; Rhodamines; Thiazoles; Thiazolidines | 2003 |
Regulation of actin-dependent cytoplasmic motility by type II phytochrome occurs within seconds in Vallisneria gigantea epidermal cells.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Chelating Agents; Cytochalasins; Cytoplasm; Cytoplasmic Streaming; Cytoskeleton; Image Processing, Computer-Assisted; Immunoblotting; Immunohistochemistry; Light; Magnoliopsida; Phalloidine; Phytochrome; Plant Epidermis; Plant Leaves; Thiazoles; Thiazolidines; Time Factors | 2003 |
Local force induced conical protrusions of phagocytic cells.
Topics: Adhesins, Bacterial; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Surface Extensions; Integrin beta1; Macrophages; Magnetics; Phagocytosis; Thiazoles; Thiazolidines; Time Factors | 2003 |
Involvement of actin polymerization in vesicle recruitment at the calyx of Held synapse.
Topics: Actins; Adenosine Triphosphate; Animals; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Enzyme Inhibitors; Ethylmaleimide; In Vitro Techniques; Macromolecular Substances; N-Ethylmaleimide-Sensitive Proteins; Patch-Clamp Techniques; Phalloidine; Presynaptic Terminals; Protein Kinase Inhibitors; Rats; Rats, Wistar; Staurosporine; Synapses; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2003 |
The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing.
Topics: Actin Cytoskeleton; Antibodies, Monoclonal; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Calcium; CD3 Complex; Cell Membrane; Cell Movement; Depsipeptides; Exocytosis; Humans; Leukemia; Lymphoma, B-Cell; Membrane Glycoproteins; Peptides, Cyclic; Perforin; Pore Forming Cytotoxic Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2003 |
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis.
Topics: Arecoline; Aspirin; Buthionine Sulfoximine; Cell Culture Techniques; Cholinergic Agonists; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Epithelial Cells; Fibroblasts; Glutathione; Humans; Immunohistochemistry; Isoenzymes; Matched-Pair Analysis; Membrane Proteins; Mouth Mucosa; Nitrobenzenes; Oral Submucous Fibrosis; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrrolidonecarboxylic Acid; Sulfonamides; Thiazoles; Thiazolidines; Transcription, Genetic; Up-Regulation | 2003 |
The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor.
Topics: Active Transport, Cell Nucleus; Amides; Animals; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Cells, Cultured; Dogs; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Muscle Cells; Muscle, Smooth; Myosin Heavy Chains; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Serum Response Factor; Signal Transduction; Thiazoles; Thiazolidines; Trachea; Transcription, Genetic | 2003 |
Effect of S 17092, a novel prolyl endopeptidase inhibitor, on substance P and alpha-melanocyte-stimulating hormone breakdown in the rat brain.
Topics: Administration, Oral; alpha-MSH; Animals; Biological Assay; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Enzyme Activation; Flavobacterium; Frontal Lobe; Hypothalamus; Indoles; Male; Medulla Oblongata; Prolyl Oligopeptidases; Protease Inhibitors; Radioimmunoassay; Rats; Rats, Wistar; Serine Endopeptidases; Substance P; Thiazoles; Thiazolidines | 2003 |
Analysis of Na+,K+-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; Cell Polarity; Cytoplasmic Vesicles; Dopamine; Green Fluorescent Proteins; GTP-Binding Proteins; Luminescent Proteins; Microtubules; Paclitaxel; Protein Transport; Pulmonary Alveoli; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Respiratory Mucosa; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Thiazoles; Thiazolidines | 2003 |
Enhanced gravitropism of roots with a disrupted cap actin cytoskeleton.
Topics: Actins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Dimethyl Sulfoxide; Dinitrobenzenes; Gravitropism; Gravity Sensing; Indoleacetic Acids; Kinetics; Plant Root Cap; Plant Roots; Signal Transduction; Sulfanilamides; Thiazoles; Thiazolidines; Time Factors; Zea mays | 2003 |
Oxothiazolidine carboxylate provides protection against hepatocellular injury seen after porta hepatis occlusion (Pringle maneuver) under hypovolemic conditions.
Topics: Animals; Constriction; Hepatic Artery; Hypovolemia; Liver; Male; Models, Animal; Portal Vein; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazoles; Thiazolidines | 2003 |
A study of the effect of surface damage on the uptake of Texas Red-BSA by schistosomula of Schistosoma mansoni.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Diffusion; Endocytosis; Fluorescent Dyes; Molecular Weight; Polylysine; Schistosoma mansoni; Serum Albumin, Bovine; Thiazoles; Thiazolidines; Time Factors; Xanthenes | 2003 |
Randomization of cortical microtubules in root epidermal cells induces root hair initiation in lettuce (Lactuca sativa L.) seedlings.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin B; Dinitrobenzenes; Lactuca; Microtubules; Paclitaxel; Plant Epidermis; Plant Roots; Sulfanilamides; Thiazoles; Thiazolidines | 2003 |
Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Catecholamines; Cattle; Cell Death; Cell Membrane; Cells, Cultured; Chromaffin Cells; Cytoskeleton; Digitonin; Elapid Venoms; Electrochemistry; Exocytosis; Membrane Fusion; Neuromuscular Blocking Agents; Secretory Vesicles; Thiazoles; Thiazolidines | 2003 |
Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice.
Topics: Animals; Bezafibrate; Body Weight; Diabetes Mellitus; Drug Therapy, Combination; Glucose; Glucose Transporter Type 2; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Monosaccharide Transport Proteins; Pancreas; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2003 |
RNP stress-granule formation is inhibited by microtubule disruption.
Topics: Actin Cytoskeleton; Animals; Arsenates; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytoplasm; Eukaryotic Cells; Microtubules; Nocodazole; Paclitaxel; Reaction Time; Stress, Physiological; Thiazoles; Thiazolidines; Vault Ribonucleoprotein Particles | 2003 |
Arrest of mammalian fibroblasts in G1 in response to actin inhibition is dependent on retinoblastoma pocket proteins but not on p53.
Topics: Actins; Animals; Antigens, Polyomavirus Transforming; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Membrane; Cell Size; Cytochalasin B; Dose-Response Relationship, Drug; Fetus; Fibroblasts; G1 Phase; HeLa Cells; Humans; Immunohistochemistry; Mice; Mice, Knockout; Neurofibromin 2; Protein Synthesis Inhibitors; Reaction Time; Retinoblastoma Protein; Thiazoles; Thiazolidines; Tumor Suppressor Protein p53 | 2003 |
[Effect of agents changing the intracellular level of reactive oxygen species on the cell cycle phase distribution in 3T3 and 3T3SV40 cell lines].
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Line, Transformed; Dose-Response Relationship, Drug; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines | 2003 |
Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells.
Topics: Actins; Adherens Junctions; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dogs; Kidney; Nectins; ras GTPase-Activating Proteins; Thiazoles; Thiazolidines | 2003 |
The role of actin filaments in the gravitropic response of snapdragon flowering shoots.
Topics: Actins; Antirrhinum; Bridged Bicyclo Compounds, Heterocyclic; Chlorpropham; Cytochalasin B; Cytochalasin D; Cytoskeleton; Dimethyl Sulfoxide; Flowers; Gravitropism; Methylmethacrylates; Plant Shoots; Thiazoles; Thiazolidines; Time Factors | 2003 |
Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Compartmentation; Cell Polarity; Centrosome; Contractile Proteins; Dynactin Complex; Dyneins; Gene Expression Regulation, Developmental; Microfilament Proteins; Microtubule-Associated Proteins; Mitosis; Mutation; Myosin Type II; Nocodazole; Profilins; Protein Serine-Threonine Kinases; Spindle Apparatus; Thiazoles; Thiazolidines; Zygote | 2003 |
Biological monitoring of carbon disulphide: kinetics of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA) in exposed workers.
Topics: Adult; Carbon Disulfide; Chemical Industry; Chromatography, High Pressure Liquid; Creatinine; Environmental Monitoring; Humans; Linear Models; Male; Middle Aged; Occupational Exposure; Thiazoles; Thiazolidines | 2002 |
Regulation of the mesangial cell myofibroblast phenotype by actin polymerization.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cells, Cultured; Cytochalasin B; Depsipeptides; Enzyme Inhibitors; Fibroblasts; Glomerular Mesangium; Humans; Intracellular Signaling Peptides and Proteins; Myocytes, Smooth Muscle; Peptides, Cyclic; Phalloidine; Phenotype; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Rats; rho-Associated Kinases; RNA Stability; RNA, Messenger; Thiazoles; Thiazolidines; Transcriptional Activation | 2003 |
[Serum sex hormone and urinary metabolites of male workers exposed to carbon disulfide].
Topics: Adult; Carbon Disulfide; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Luteinizing Hormone; Male; Occupational Exposure; Prolactin; Testosterone; Thiazoles; Thiazolidines | 1999 |
PAT5A: a partial agonist of peroxisome proliferator-activated receptor gamma is a potent antidiabetic thiazolidinedione yet weakly adipogenic.
Topics: 3T3 Cells; Adipocytes; Animals; Binding Sites; Carrier Proteins; Cyclic AMP Response Element-Binding Protein; Histone Acetyltransferases; Hypoglycemic Agents; Mediator Complex Subunit 1; Mice; Nuclear Receptor Coactivator 1; Pyridines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2003 |
Stretch-induced contractile differentiation of vascular smooth muscle: sensitivity to actin polymerization inhibitors.
Topics: Actins; Angiotensin II; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Culture Techniques; Cytochalasin D; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Female; MAP Kinase Signaling System; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Portal Vein; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; Stress, Mechanical; Thiazoles; Thiazolidines | 2003 |
An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast.
Topics: Actin Cytoskeleton; Actin-Related Protein 2; Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Membrane; Cytoskeletal Proteins; Endocytosis; Fungal Proteins; Macromolecular Substances; Microfilament Proteins; Microscopy, Electron; Mutation; Protein Structure, Tertiary; Protein Transport; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Transport Vesicles; Vacuoles; Wiskott-Aldrich Syndrome Protein | 2003 |
Accumulation of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA) among workers occupationally exposed to carbon disulfide for 1 week.
Topics: Adult; Carbon Disulfide; Chemical Industry; Environmental Monitoring; Humans; Male; Middle Aged; Models, Theoretical; Occupational Exposure; Personnel Staffing and Scheduling; Thiazoles; Thiazolidines; Workplace | 2003 |
Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo.
Topics: Actin Depolymerizing Factors; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dendrites; Dentate Gyrus; Immunohistochemistry; Long-Term Potentiation; Male; Microfilament Proteins; Microscopy, Electron; Models, Neurological; Neuropeptides; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Thiazoles; Thiazolidines | 2003 |
L-2-oxothiazolidine-4-carboxylate supplementation in murine gamma-GT deficiency.
Topics: Animals; Body Weight; Dietary Supplements; gamma-Glutamyltransferase; Genotype; Glutathione; Growth Disorders; Liver; Mice; Mice, Knockout; Pyrrolidonecarboxylic Acid; Reproduction; Thiazoles; Thiazolidines | 2003 |
Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Fermentation; Hedgehog Proteins; Humans; Immunoglobulin Fc Fragments; Male; Methionine; Mice; Mice, Inbred C3H; Molecular Sequence Data; Peptide Mapping; Pichia; Proprotein Convertases; Protein Engineering; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines; Trans-Activators | 2003 |
Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C.
Topics: Actins; Animals; Binding Sites; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytoskeleton; Electrophysiology; Enzyme Activation; Humans; Ions; Mice; Microscopy, Fluorescence; Mutation; Oocytes; Phalloidine; Phosphorylation; Point Mutation; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA, Complementary; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured; Xenopus; Xenopus laevis | 2003 |
Equatorial retention of the contractile actin ring by microtubules during cytokinesis.
Topics: Actins; Anaphase; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Carbamates; Cell Cycle Proteins; Cell Division; Cell Nucleus; Cytoskeletal Proteins; Interphase; Microtubule-Organizing Center; Microtubules; Mitosis; Mutation; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Thiazoles; Thiazolidines; Tubulin | 2003 |
Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions.
Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Cricetinae; Cysteine; Free Radical Scavengers; Humans; Hybrid Cells; Ions; Linear Energy Transfer; Mutation; Thiazoles; Thiazolidines | 2002 |
Immunodetection of spectrin-like proteins in yeasts.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Extracts; Culture Media; Fluorescent Antibody Technique; Fungal Proteins; Humans; Immunoblotting; Membrane Proteins; Mutation; Osmotic Pressure; Saccharomyces cerevisiae; Schizosaccharomyces; Spectrin; Thiazoles; Thiazolidines | 2003 |
Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expression.
Topics: Actin Cytoskeleton; Bacterial Proteins; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Cytokines; Cytoskeleton; Depsipeptides; Enzyme Inhibitors; Eukaryotic Cells; Gene Expression Regulation, Enzymologic; Humans; Intracellular Signaling Peptides and Proteins; Nitric Oxide; Nitric Oxide Synthase; Peptides, Cyclic; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Serum Response Factor; Thiazoles; Thiazolidines; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Enzyme Inhibitors; Gluconeogenesis; Glutathione; Intracellular Membranes; Kidney Cortex; Kidney Tubules; Male; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Rabbits; Thiazoles; Thiazolidines | 2003 |
Possible involvement of energy metabolism in the change of cytoplasm organization induced by a protein phosphatase inhibitor, calyculin A, in root hair cells of Limnobium stoloniferum.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cytoplasm; Enzyme Inhibitors; Hydrocharitaceae; Indole Alkaloids; Marine Toxins; Myosins; Oxazoles; Phosphoprotein Phosphatases; Plant Roots; Sodium Nitrite; Thiazoles; Thiazolidines | 2003 |
Downregulation of profilin with antisense oligodeoxynucleotides inhibits force development during stimulation of smooth muscle.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Contractile Proteins; Dogs; Down-Regulation; In Vitro Techniques; Microfilament Proteins; Muscle, Smooth, Vascular; Myosin Light Chains; Norepinephrine; Oligodeoxyribonucleotides, Antisense; Phosphorylation; Polymers; Potassium Chloride; Profilins; Thiazoles; Thiazolidines; Vasoconstriction | 2003 |
Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis.
Topics: Actin-Related Protein 2; Actin-Related Protein 2-3 Complex; Actin-Related Protein 3; Actins; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cell Surface Extensions; Cytoskeletal Proteins; Hypocotyl; Microfilament Proteins; Molecular Sequence Data; Multigene Family; Mutation; Plant Epidermis; Plant Roots; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines; Vacuoles | 2003 |
Low dose latrunculin-A inhibits dexamethasone-induced changes in the actin cytoskeleton and alters extracellular matrix protein expression in cultured human trabecular meshwork cells.
Topics: Actins; Blotting, Northern; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Dexamethasone; Extracellular Matrix Proteins; Fibronectins; Humans; Thiazoles; Thiazolidines; Thrombospondin 1; Trabecular Meshwork | 2003 |
Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation.
Topics: Actins; Blotting, Northern; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Collagen; Collagen Type I; Collagen Type IV; Cytochalasin D; Cytoskeleton; DNA, Complementary; Dose-Response Relationship, Drug; Glomerular Mesangium; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Matrix Metalloproteinases; Phosphorylation; Protein Binding; Recombinant Proteins; RNA; RNA, Messenger; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Interaction of viscotoxins A3 and B with membrane model systems: implications to their mechanism of action.
Topics: Anisotropy; Drug Interactions; Lipid Bilayers; Macromolecular Substances; Membrane Fluidity; Membranes, Artificial; Permeability; Phospholipids; Plant Proteins; Porosity; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Temperature; Thiazoles; Thiazolidines | 2003 |
Inhibition of arterial thrombosis by a protease-activated receptor 1 antagonist, FR171113, in the guinea pig.
Topics: Animals; Arginine; Benzamides; Bleeding Time; Blood Coagulation; Carotid Artery Thrombosis; Chlorides; Dose-Response Relationship, Drug; Ferric Compounds; Guinea Pigs; Heparin; Injections, Subcutaneous; Male; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptor, PAR-1; Receptors, Thrombin; Sulfonamides; Thiazoles; Thiazolidines | 2003 |
Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat.
Topics: Absorption; Administration, Oral; Animals; Bile; Biological Availability; Dose-Response Relationship, Drug; Expectorants; Female; Injections, Intravenous; Liver; Male; Organ Specificity; Rats; Rats, Sprague-Dawley; Sex Factors; Thiazoles; Thiazolidines; Tissue Distribution | 2003 |
NAADP activates a Ca2+ current that is dependent on F-actin cytoskeleton.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Calcium Signaling; Cell Membrane; Depsipeptides; Electric Conductivity; Models, Biological; NADP; Oocytes; Patch-Clamp Techniques; Peptides, Cyclic; Starfish; Thiazoles; Thiazolidines | 2003 |
Intracellular mediators of granulysin-induced cell death.
Topics: Antigens, Differentiation, T-Lymphocyte; Apoptosis; Calcium; Cell Death; Culture Media, Conditioned; Cytotoxicity, Immunologic; Down-Regulation; Fura-2; Glutathione; Humans; Intracellular Fluid; Jurkat Cells; Mitochondria; Peptides; Potassium; Protein Transport; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines; Up-Regulation | 2003 |
The association of peroxisomes with the developing cell plate in dividing onion root cells depends on actin microfilaments and myosin.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytochalasin D; Cytoskeleton; Diacetyl; Green Fluorescent Proteins; Immunohistochemistry; Luminescent Proteins; Microscopy, Immunoelectron; Myosins; Onions; Peroxisomes; Plant Epidermis; Plant Roots; Thiazoles; Thiazolidines | 2003 |
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines | 2003 |
Insulin promotes formation of polymerized microtubules by a phosphatidylinositol 3-kinase-independent, actin-dependent pathway in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Actins; Adipocytes; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Enzyme Activation; Glucose Transporter Type 4; Insulin; Mice; Microtubules; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Nocodazole; Phosphatidylinositol 3-Kinases; Polymers; Protein-Tyrosine Kinases; Thiazoles; Thiazolidines; Time Factors; Tubulin | 2003 |
Studies of the metabolism of thiazolidine carboxylic acid by rat liver homogenate.
Topics: Animals; Biochemical Phenomena; Carboxylic Acids; Liver; Rats; Thiazoles; Thiazolidines | 1956 |
N-formylcysteine synthesis in mitochondria from formaldehyde and L-cysteine via thiazolidinecarboxylic acid.
Topics: Cysteine; Formaldehyde; Liver; Mitochondria; Thiazoles; Thiazolidines | 1957 |
2-Thiazolidinethione-4-carboxylic acid from the reaction of captan with cysteine.
Topics: Antifungal Agents; Captan; Carboxylic Acids; Cysteine; Fungicides, Industrial; Thiazoles; Thiazolidines | 1958 |
[Thiazolidine-carboxylic acid, iminothiazolidine-carboxylic acid and thiazane-carboxylic acid as liver protective substances in comparison with cysteine].
Topics: Carboxylic Acids; Cysteine; Digestion; Humans; Liver; Thiazoles; Thiazolidines | 1958 |
An infrared study of the hydrolysis of a thiazolidine.
Topics: Hydrolysis; Solutions; Spectrophotometry, Infrared; Thiazoles; Thiazolidines | 1958 |
The replacement by thiazolidinecarboxylic acid of exogenous cystine and cysteine.
Topics: Cysteine; Cystine; Humans; Thiazoles; Thiazolidines | 1958 |
Thiazolidines and aminoalkylthiosulfuric acids as protecting agents against ionizing radiation.
Topics: Radiation Protection; Radiation, Ionizing; Thiazoles; Thiazolidines; Thiosulfates | 1961 |
A new development in the formation reaction of thiazolidines from 2-aminolkanethiols and carbonyl compounds.
Topics: Thiazoles; Thiazolidines | 1962 |
[STUDIES ON THE THIAZOLIDINECARBOXYLIC ACID DERIVATIVES AS THE PROTECTIVE AND RESTORATIVE AGENTS AGAINST RADIATION INJURY].
Topics: Chemistry, Pharmaceutical; Mice; Pharmacology; Pharmacy; Radiation Effects; Radiation Injuries; Radiation-Protective Agents; Research; Thiazoles; Thiazolidines | 1963 |
[EXPERIENCE WITH THE USE OF LEUCOGEN IN THE TREATMENT OF CHRONIC OCCUPATIONAL BENZENE POISONINGS].
Topics: Benzene; Humans; Leukocyte Count; Leukopenia; Occupational Diseases; Thiazoles; Thiazolidines; Toxicology; USSR | 1963 |
[A NEW HEPATO-PROTECTOR, THIAZOLIDINE-4-CARBOXYLIC ACID. PHARMACOLOGICAL STUDY AND CLINICAL TRIALS IN INFECTIOUS HEPATITIS].
Topics: Communicable Diseases; Hepatitis; Hepatitis A; Humans; Research; Thiazoles; Thiazolidines | 1963 |
[OBSERVATIONS ON THE LEUKOCYTOTIC ACTION OF 2-(ALPHA-PHENYL-2-CARBETHOXYMETHYL)-THIAZOLIDINE-4-CARBOXYLIC ACID].
Topics: Blood; Leukocytes; Leukocytosis; Leukopenia; Mechlorethamine; Pharmacology; Rabbits; Research; Thiazoles; Thiazolidines | 1964 |
PHARMACOLOGICAL AND TOXICOLOGICAL COMPOUNDS AS PROTECTIVE OR THERAPEUTIC AGENTS AGAINST RADIATION INJURY IN EXPERIMENTAL ANIMALS. I. EFFECTS OF 2-IMINO-THIAZOLIDINE-4-CARBOXYLIC ACID ON THE RADIOPROTECTIVE ACTIVITY OF VARIOUS CHEMICAL AGENTS. REP NO. 51.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Laboratory; beta-Aminoethyl Isothiourea; Mercaptoethylamines; Mice; Pharmacology; Propiophenones; Radiation Injuries; Radiation-Protective Agents; Research; Thiazoles; Thiazolidines; Valine | 1964 |
[RADIOPROTECTIVE ACTION OF THIAZOLIDINES].
Topics: Animals; Erythrocytes; Methemoglobin; Mice; Pharmacology; Radiation-Protective Agents; Research; Thiazoles; Thiazolidines | 1964 |
[USE OF A RADIOMIMETIC (ERYTHROCYTIC) MODEL FOR THE STUDY OF POTENTIAL RADIOPROTECTIVE AGENTS OF THE THIAZOLIDINE GROUP].
Topics: Erythrocytes; Models, Theoretical; Pharmacology; Radiation-Protective Agents; Research; Thiazoles; Thiazolidines | 1964 |
[EFFECT OF THIAZOLIDINE-4-CARBOXYLIC ACID ON THE DEVELOPMENT OF THE EGG OF THE SEA URCHIN PARACENTROTUS LIVIDUS].
Topics: Animals; Echinodermata; Ovum; Paracentrotus; Pharmacology; Proline; Research; Sea Urchins; Thiazoles; Thiazolidines | 1964 |
[THERAPEUTIC ACTION OF THIAZOLIDINE-CARBOXYLIC ACID IN HEPATOLOGY].
Topics: Carboxylic Acids; Gastroenterology; Humans; Lipotropic Agents; Liver Diseases; Thiazoles; Thiazolidines | 1965 |
INHIBITION OF PROLINE-C14 INCORPORATION INTO RAT LIVER RIBOSOMES BY THIAZOLIDINE-4-CARBOXYLIC ACID IN A CELL-FREE SYSTEM.
Topics: Carbon Isotopes; Cell-Free System; Hydroxyproline; Liver; Metabolism; Proline; Rats; Research; Ribosomes; RNA; Sulfur Isotopes; Thiazoles; Thiazolidines | 1965 |
[PREPARATION AND PROPERTIES OF A NEW THIAZOLIDINE DERIVATIVE].
Topics: Thiazoles; Thiazolidines | 1965 |
STUDIES OF SOME SUBSTANCES WITH ANTIVIRAL ACTIVITY. II. 2,4-DIOXO-5-THIAZOLIDINE ACETIC ACID DERIVATIVES (DFT) AS AN INHIBITOR OF GROWTH OF HERPES VIRUS AND POLIOVIRUS TYPE I IN CELL CULTURES OF HUMAN EMBRYONIC KIDNEYS.
Topics: Acetates; Acetic Acid; Antiviral Agents; Cytopathogenic Effect, Viral; Enterovirus C, Human; Herpesviridae; Pharmacology; Poliovirus; Research; Simplexvirus; Thiazoles; Thiazolidines; Tissue Culture Techniques; Virus Cultivation | 1965 |
[Amidine derivatives of thiazolidine].
Topics: Amidines; Humans; Thiazoles; Thiazolidines | 1954 |
[Synthesis and antibacterial activity of antipyrine derivative. I. 4-Thiazoline-2-thiones, dithiocarbamic acid esters and rhodanines].
Topics: Anti-Bacterial Agents; Antipyrine; Esters; Rhodanine; Thiazoles; Thiazolidines | 1962 |
F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cells.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cytoskeleton; Immunohistochemistry; Molecular Conformation; Neurons; PC12 Cells; Phalloidine; Potassium Chloride; Protein Isoforms; Protein Kinase C; Rats; Thiazoles; Thiazolidines | 2003 |
Targeted chemical disruption of clathrin function in living cells.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Clathrin; Cloning, Molecular; Coated Pits, Cell-Membrane; Cricetinae; Cricetulus; Fluorescence Recovery After Photobleaching; Microscopy; Microscopy, Electron; Protein Binding; Tacrolimus; Tacrolimus Binding Proteins; Thiazoles; Thiazolidines | 2003 |
Distinct LPS-induced signals regulate LPS uptake and morphological changes in medfly hemocytes.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Ceratitis capitata; Cytochalasin D; Cytoskeleton; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Hemocytes; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; ras Proteins; rho GTP-Binding Proteins; Signal Transduction; Thiazoles; Thiazolidines | 2003 |
The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells.
Topics: Animals; Carbon Radioisotopes; Cell Count; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Cysteine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hybrid Cells; Iron Radioisotopes; Linear Energy Transfer; Lymphocytes; Mutation; Prodrugs; Radiation Dosage; Radiation Tolerance; Radiation-Protective Agents; Thiazoles; Thiazolidines | 2003 |
Disruption of microtubules inhibits cytoplasmic ribonucleoprotein stress granule formation.
Topics: Actins; Animals; Arsenates; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chlorocebus aethiops; Cytoplasmic Granules; Cytoskeleton; Eukaryotic Initiation Factor-3; Fibroblasts; Marine Toxins; Microtubules; Nocodazole; Paclitaxel; Phosphorylation; Prokaryotic Initiation Factor-3; Ribonucleoproteins; Stress Fibers; Thiazoles; Thiazolidines; Vinblastine | 2003 |
Active internalization of the Penicillium chrysogenum antifungal protein PAF in sensitive aspergilli.
Topics: Adenosine Triphosphate; Antifungal Agents; Aspergillus; Bridged Bicyclo Compounds, Heterocyclic; Cytoplasm; Fluorescent Antibody Technique; Fungal Proteins; Penicillium; Penicillium chrysogenum; Thiazoles; Thiazolidines | 2003 |
Quantitative analysis of dipeptidyl peptidase inhibitor P32/98 and its main metabolite in rat, dog, mouse, monkey, human plasma and human urine using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic evaluation.
Topics: Animals; Calibration; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dogs; Enzyme Inhibitors; Haplorhini; Humans; Mice; Pentanoic Acids; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Thiazoles; Thiazolidines | 2003 |
Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Division; Cytoskeleton; Fluorescent Dyes; Microscopy, Fluorescence; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Thiazoles; Thiazolidines; Time Factors | 2003 |
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cattle; Chromaffin Cells; Depsipeptides; Exocytosis; Microscopy, Electron; Myosin Heavy Chains; Myosin Type V; PC12 Cells; Peptides, Cyclic; rab GTP-Binding Proteins; rab27 GTP-Binding Proteins; Rats; Secretory Vesicles; Thiazoles; Thiazolidines | 2003 |
Catalysis-based total synthesis of latrunculin B.
Topics: Acylation; Alkynes; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cross-Linking Reagents; Cyclization; Iron; Molecular Structure; Thiazoles; Thiazolidines | 2003 |
Novel PPARgamma-dependent and independent effects for thiazolidinediones.
Topics: Animals; Bezafibrate; Body Weight; Chromans; Diabetes Mellitus, Type 2; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Proteins; Mice; Monocytes; Pancreas; Pioglitazone; PPAR alpha; PPAR gamma; Pregnancy Proteins; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Troglitazone; Tumor Necrosis Factor-alpha | 2003 |
The actin cytoskeleton facilitates complement-mediated activation of cytosolic phospholipase A2.
Topics: Actin Cytoskeleton; Animals; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; Complement System Proteins; Cytochalasin D; Enzyme Activation; Epithelial Cells; ErbB Receptors; Group IV Phospholipases A2; Kidney Glomerulus; Phospholipases A; Phospholipases A2; Rats; rhoA GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines | 2004 |
Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cell Polarity; Microscopy, Confocal; Microtubule-Associated Proteins; Microtubules; Protein Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiazoles; Thiazolidines; Toxins, Biological | 2003 |
The promotive effect of latrunculin B on maize root gravitropism is concentration dependent.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Dose-Response Relationship, Drug; Gravitation; Gravitropism; Marine Toxins; Plant Root Cap; Plant Roots; Rotation; Thiazoles; Thiazolidines; Time Factors; Zea mays | 2003 |
Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytoplasmic Streaming; Endoplasmic Reticulum; Intracellular Membranes; Mutation; Myosin Heavy Chains; Myosin Type V; RNA-Binding Proteins; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2003 |
Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid.
Topics: Animals; Carbon; Cytosol; Escherichia coli; Humans; Hydrolysis; In Vitro Techniques; Kinetics; Liver; Mice; Nitrates; Oxygen; Pharmaceutical Preparations; Pyroglutamyl-Peptidase I; Pyrrolidonecarboxylic Acid; Rats; Substrate Specificity; Sulfur; Thiazoles; Thiazolidines; Xenobiotics | 2004 |
Disruption of the actin cytoskeleton up-regulates iNOS expression in vascular smooth muscle cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cytoskeleton; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Up-Regulation | 2004 |
Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell.
Topics: Animals; Anisomycin; Arsenites; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Coated Materials, Biocompatible; Cytochalasin D; Cytoskeleton; Diffusion; Female; Growth Substances; Heat-Shock Proteins; Interleukin-1; Marine Toxins; Microspheres; Motion; Myocytes, Smooth Muscle; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines; Trachea | 2004 |
Actin-dependent fluid-phase endocytosis in inner cortex cells of maize root apices.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Depsipeptides; Endocytosis; Fluorescent Dyes; Immunohistochemistry; Isoquinolines; Microscopy, Immunoelectron; Myosins; Peptides, Cyclic; Plant Roots; Thiazoles; Thiazolidines; Zea mays | 2004 |
Microtubules and microfilaments coordinate to direct a fountain streaming pattern in elongating conifer pollen tube tips.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Dinitrobenzenes; Endoplasmic Reticulum; Flowers; Microtubules; Organelles; Picea; Sulfanilamides; Thiazoles; Thiazolidines | 2004 |
Association with membrane protrusions makes ErbB2 an internalization-resistant receptor.
Topics: Actins; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biotin; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Membrane; Centrifugation, Density Gradient; Cholesterol; Clathrin; Cross-Linking Reagents; Cytoskeleton; Detergents; Down-Regulation; Endosomes; Epidermal Growth Factor; Humans; Immunohistochemistry; Ligands; Membrane Microdomains; Microscopy, Confocal; Microscopy, Electron; Microscopy, Fluorescence; Models, Biological; Neuregulin-1; Protein Binding; Protein Structure, Tertiary; Receptor, ErbB-2; Receptors, Transferrin; Signal Transduction; Sucrose; Thiazoles; Thiazolidines; Trastuzumab | 2004 |
Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton.
Topics: Actins; Alanine; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; COS Cells; Cytoskeleton; Dose-Response Relationship, Drug; Gene Deletion; Guanine Nucleotide Exchange Factors; Humans; Immunoblotting; Luciferases; Models, Genetic; Molecular Sequence Data; Mutation; Neurons; Precipitin Tests; Protein Structure, Tertiary; Receptors, Glutamate; Rho Guanine Nucleotide Exchange Factors; Signal Transduction; Thiazoles; Thiazolidines; Transfection | 2004 |
Calcium transients regulate patterned actin assembly during myofibrillogenesis.
Topics: Actin Cytoskeleton; Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; CapZ Actin Capping Protein; Connectin; Cytochalasin D; Depsipeptides; Microfilament Proteins; Muscle Development; Muscle Proteins; Myosin-Light-Chain Kinase; Myosins; Naphthalenes; Peptides, Cyclic; Protein Kinases; Sarcomeres; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Xenopus | 2004 |
A novel form of actin in Leishmania: molecular characterisation, subcellular localisation and association with subpellicular microtubules.
Topics: Actins; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Cytochalasin D; DNA, Protozoan; Leishmania; Microscopy, Fluorescence; Microscopy, Immunoelectron; Microtubules; Models, Molecular; Molecular Sequence Data; Molecular Weight; Organelles; Phalloidine; Protozoan Proteins; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Staining and Labeling; Thiazoles; Thiazolidines | 2004 |
Thioproline inhibits development of esophageal adenocarcinoma induced by gastroduodenal reflux in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Barrett Esophagus; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; Diet; Duodenogastric Reflux; Duodenum; Epithelium; Esophageal Neoplasms; Immunoenzyme Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroso Compounds; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Nitrogen Species; Thiazoles; Thiazolidines | 2004 |
[Urinary excretion pattern of 2-thio-thiazolidine-4-carboxylic acid in workers exposed to carbon disulfide].
Topics: Adult; Carbon Disulfide; Environmental Monitoring; Humans; Male; Middle Aged; Occupational Exposure; Thiazoles; Thiazolidines | 2003 |
Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor.
Topics: Administration, Oral; Animals; Bacterial Toxins; Benzoates; Body Fluids; Cell Line; Chlorides; Cholera Toxin; Cyclic AMP; Cyclic GMP; Electric Conductivity; Enterotoxins; Escherichia coli Proteins; Humans; Injections, Intraperitoneal; Intestinal Mucosa; Intestines; Ion Channels; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Tissue Distribution | 2004 |
Roles of a conserved family of adaptor proteins, Lnk, SH2-B, and APS, for mast cell development, growth, and functions: APS-deficiency causes augmented degranulation and reduced actin assembly.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Carrier Proteins; Cell Adhesion; Cell Division; Cell Movement; Cell Separation; Cell Survival; Cross-Linking Reagents; Cytokines; Cytoskeleton; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Immunoblotting; Immunohistochemistry; Interleukin-3; Intracellular Signaling Peptides and Proteins; Mast Cells; Membrane Proteins; Mice; Mice, Transgenic; Protein Binding; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins c-kit; Receptors, Cytokine; Receptors, IgE; Signal Transduction; Thiazoles; Thiazolidines; Time Factors | 2004 |
[Clinical results with a combined thiazolidine derivative (priatan) in asthma therapy].
Topics: Asthma; Humans; Thiazoles; Thiazolidines | 1951 |
Reorganization of microfilaments and microtubules by thermal stress in two-cell bovine embryos.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Nucleus; Cleavage Stage, Ovum; Cytoplasm; Female; Heat-Shock Response; Lactones; Macrolides; Microscopy, Electron; Microtubules; Mitochondrial Swelling; Movement; Paclitaxel; Thiazoles; Thiazolidines | 2004 |
Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae.
Topics: Actins; Active Transport, Cell Nucleus; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cytoskeleton; Nitrogen; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Protein Transport; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Thiazoles; Thiazolidines; Transcription Factors | 2004 |
Enantioseparation in capillary chromatography and capillary electrochromatography using polysaccharide-type chiral stationary phases.
Topics: Carbamates; Cellulose; Chromatography; Electrophoresis, Capillary; Molecular Conformation; Molecular Structure; Phenylcarbamates; Polysaccharides; Silanes; Stereoisomerism; Thalidomide; Thiazoles; Thiazolidines | 2004 |
Secretagogue-induced translocation of CRHSP-28 within an early apical endosomal compartment in acinar cells.
Topics: Animals; Biological Transport; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Endocytosis; Endosomes; Fluorescent Antibody Technique; Membrane Proteins; Microscopy, Immunoelectron; Pancreas; Phosphoproteins; Protein Synthesis Inhibitors; Rats; Sincalide; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2004 |
Distinct roles of hippocampal de novo protein synthesis and actin rearrangement in extinction of contextual fear.
Topics: Acoustic Stimulation; Actins; Animals; Anisomycin; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Classical; Cytochalasin D; Cytoskeleton; Electroshock; Extinction, Psychological; Fear; Hippocampus; Male; Mice; Mice, Inbred C57BL; Protein Biosynthesis; Protein Synthesis Inhibitors; Thiazoles; Thiazolidines | 2004 |
Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cattle; Cloning, Molecular; Coronary Vessels; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Molecular Sequence Data; Nitrates; Pyrrolidonecarboxylic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Thiazoles; Thiazolidines; Vasodilator Agents | 2004 |
A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways.
Topics: Animals; Benzoates; Body Fluids; Bronchi; Cells, Cultured; Chlorides; Cholinergic Agents; Colforsin; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocrine Glands; Humans; Hydrogen-Ion Concentration; Pilocarpine; Second Messenger Systems; Sodium; Swine; Thapsigargin; Thiazoles; Thiazolidines; Viscosity | 2004 |
Effects of wortmannin and latrunculin A on slow endocytosis at the frog neuromuscular junction.
Topics: Acetylcholine; Actins; Androstadienes; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Electrophysiology; Endocytosis; Enzyme Inhibitors; Exocytosis; Fluorescent Dyes; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Microelectrodes; Microscopy, Electron; Microscopy, Fluorescence; Motor Endplate; Neuromuscular Junction; Phosphoinositide-3 Kinase Inhibitors; Presynaptic Terminals; Rana pipiens; Signal Transduction; Thiazoles; Thiazolidines; Wortmannin | 2004 |
Uncoated endocytic vesicles require the unconventional myosin, Myo6, for rapid transport through actin barriers.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Dimethyl Sulfoxide; Endocytosis; Endosomes; Green Fluorescent Proteins; Humans; Microscopy, Fluorescence; Myosin Heavy Chains; Protein Transport; Thiazoles; Thiazolidines; Transferrin; Transport Vesicles | 2004 |
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity.
Topics: Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Drug Evaluation, Preclinical; Gene Expression Regulation; Imidazoles; Insulin; Irbesartan; Losartan; Male; Mice; Models, Molecular; Myoblasts; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Structure-Activity Relationship; Telmisartan; Tetrazoles; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Triglycerides; Valine; Valsartan; Weight Gain | 2004 |
Mechanism controlling perpendicular alignment of the spindle to the axis of cell division in fission yeast.
Topics: Actins; Anaphase; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Contractile Proteins; Cytoskeleton; Microtubules; Myosin Type V; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus; Thiazoles; Thiazolidines | 2004 |
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cortactin; Cricetinae; Enzyme Activation; Microfilament Proteins; Osmotic Pressure; Peptides; Phosphorylation; Phosphotyrosine; Polymers; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Thiazoles; Thiazolidines; Transfection; Tyrosine | 2004 |
A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Surface Extensions; Chemotaxis; Enzyme Inhibitors; Imidazoles; Immunoblotting; Intracellular Signaling Peptides and Proteins; Lipid Metabolism; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; PTEN Phosphohydrolase; Pyridines; Thiazoles; Thiazolidines; Time Factors; Tumor Suppressor Proteins | 2004 |
Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dipeptides; Indoles; Kidney; Kidney Cortex; Male; Myocardium; Nitriles; Oligopeptides; Organ Specificity; Proline; Prolyl Oligopeptidases; Protease Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Thiazoles; Thiazolidines; Thymosin | 2004 |
Actin polymerization-driven molecular movement of mDia1 in living cells.
Topics: Actin Cytoskeleton; Actins; Animals; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cytochalasin D; Depsipeptides; Formins; Mice; Microtubules; Movement; Mutation; Myosins; Peptides, Cyclic; Recombinant Fusion Proteins; rhoA GTP-Binding Protein; Thiazoles; Thiazolidines; Xenopus | 2004 |
Experimental evidence for the limiting role of enzymatic reactions in chemoattractant-induced pseudopod extension in human neutrophils.
Topics: Actins; Alkaloids; Androstadienes; Benzophenanthridines; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Cytoskeleton; Enzyme Inhibitors; Enzymes; Humans; Kinetics; Lipids; Models, Chemical; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phenanthridines; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Kinase C; Receptors, G-Protein-Coupled; Temperature; Thiazoles; Thiazolidines; Time Factors; Wortmannin | 2004 |
The major outer sheath protein of Treponema denticola inhibits the binding step of collagen phagocytosis in fibroblasts.
Topics: Actins; Animals; Antigens, Surface; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Line; Collagen; Fibroblasts; Gingiva; Humans; Integrin beta1; Phagocytosis; Porins; Protein Binding; Rats; Thiazoles; Thiazolidines; Treponema; Treponemal Infections | 2004 |
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth.
Topics: Animals; bcl-X Protein; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Genetic Techniques; Genetic Vectors; Humans; Mammary Neoplasms, Experimental; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Neoplasm Metastasis; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Thiazolidines | 2004 |
The role of actin in the regulation of dendritic spine morphology and bidirectional synaptic plasticity.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Microscopy, Electron; Neuronal Plasticity; Neurons; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Synapses; Thiazoles; Thiazolidines | 2004 |
The effect of personal factors on the relationship between carbon disulfide exposure and urinary 2-thiothiazolidine-4-carboxylic acid levels in rayon manufacturing workers.
Topics: Administration, Cutaneous; Adult; Biomarkers; Carbon Disulfide; Cellulose; Chemical Industry; Female; Humans; Hygiene; Male; Middle Aged; Occupational Exposure; Protective Clothing; Skin Diseases; Thiazoles; Thiazolidines | 2004 |
F-actin-dependent insolubility of chromatin-modifying components.
Topics: Acetyltransferases; Actins; Bridged Bicyclo Compounds, Heterocyclic; Chromatin; Histone Acetyltransferases; Histone Deacetylases; Nocodazole; Nuclear Proteins; Solubility; Thiazoles; Thiazolidines | 2004 |
Regulation of anoikis by Cdc42 and Rac1.
Topics: Actins; Animals; Anoikis; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Line; Cell Survival; Dogs; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Feedback, Physiological; JNK Mitogen-Activated Protein Kinases; Kidney; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines | 2004 |
Activation of Arp2/3 complex: addition of the first subunit of the new filament by a WASP protein triggers rapid ATP hydrolysis on Arp2.
Topics: Acanthamoeba; Actin-Related Protein 2; Actin-Related Protein 3; Actins; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Dimerization; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Microscopy, Fluorescence; Phosphates; Polymers; Protein Binding; Thiazoles; Thiazolidines; Wiskott-Aldrich Syndrome Protein | 2004 |
Role of cytoskeleton components in measles virus replication.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chlorocebus aethiops; Cytoskeletal Proteins; Fluorescent Antibody Technique; Giant Cells; Measles virus; Microtubules; Nocodazole; Thiazoles; Thiazolidines; Tubulin; Vero Cells; Viral Proteins; Virus Replication | 2004 |
Actin filaments regulate voltage-gated ion channels in salamander retinal ganglion cells.
Topics: Actins; Ambystoma; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels, L-Type; Cell Membrane; Cytochalasin B; Membrane Potentials; Phalloidine; Potassium Channels, Voltage-Gated; Retinal Ganglion Cells; Thiazoles; Thiazolidines | 2004 |
Localization of selenium-binding protein at the tips of rapidly extending protrusions.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cell Shape; Cell Surface Extensions; Cytochalasin D; Deoxyribonuclease I; Humans; Immunohistochemistry; Microscopy, Fluorescence; Models, Biological; Neurites; Phalloidine; Phosphoinositide-3 Kinase Inhibitors; Pseudopodia; Selenium-Binding Proteins; Thiazoles; Thiazolidines | 2004 |
Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly.
Topics: Actins; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Polarity; Centrosome; Cross-Linking Reagents; Drosophila; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Hybridomas; Lectins; Marine Toxins; Marsupialia; Mitosis; Models, Biological; Movement; Myosin Type II; Nuclear Envelope; Pyridines; RNA Interference; Spindle Apparatus; Thiazoles; Thiazolidines; Time Factors | 2004 |
Roles of Ca2+, hyperpolarization and cyclic nucleotide-activated channel activation, and actin in temporal synaptic tagging.
Topics: Actins; Animals; Astacoidea; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Colforsin; Cyclic AMP; Cyclic Nucleotide-Gated Cation Channels; Cytochalasin D; Electric Stimulation; In Vitro Techniques; Ion Channels; Long-Term Potentiation; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Pyrimidines; Thiazoles; Thiazolidines; Time Factors | 2004 |
Decomposition of 2-mercaptothiazoline in aqueous solution by ozonation.
Topics: Carbon; Kinetics; Ozone; Quaternary Ammonium Compounds; Sulfates; Thiazoles; Thiazolidines; Waste Disposal, Fluid | 2004 |
Interactions between auxin transport and the actin cytoskeleton in developmental polarity of Fucus distichus embryos in response to light and gravity.
Topics: Actins; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Fucus; Gravitropism; Indoleacetic Acids; Light; Phototropism; Phthalimides; Seeds; Thiazoles; Thiazolidines | 2004 |
Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.
Topics: 3T3-L1 Cells; Actins; Adipocytes; Animals; Bacterial Proteins; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Membrane; Cholesterol; Clathrin; Cortactin; Cytotoxins; DNA, Complementary; Dynamins; Endocytosis; Endosomes; Fibroblasts; Gene Expression Regulation; Glucose Transporter Type 4; Golgi Apparatus; Golgi Matrix Proteins; Membrane Proteins; Mice; Microfilament Proteins; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Nerve Tissue Proteins; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Qa-SNARE Proteins; Receptors, Transferrin; Thiazoles; Thiazolidines; Time Factors; trans-Golgi Network; Transfection; Vesicular Transport Proteins; Wiskott-Aldrich Syndrome Protein, Neuronal | 2004 |
A one-pot total synthesis of crambin.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Cysteine; Gas Chromatography-Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Plant Proteins; Protein Conformation; Protein Folding; Thiazoles; Thiazolidines | 2004 |
Actin- and protein-4.1-containing filaments link nuclear pore complexes to subnuclear organelles in Xenopus oocyte nuclei.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleolus; Cell Nucleus; Chromatin; Coiled Bodies; Cytoskeletal Proteins; Depsipeptides; Female; Immunohistochemistry; Membrane Proteins; Microscopy, Electron, Scanning; Nuclear Pore; Oocytes; Protein Binding; Thiazoles; Thiazolidines; Xenopus | 2004 |
Control of actin dynamics by p38 MAP kinase - Hsp27 distribution in the lamellipodium of smooth muscle cells.
Topics: Actins; Animals; Aorta; Becaplermin; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion Molecules; Cell Movement; Cytochalasin D; Cytoskeleton; Endothelium, Vascular; Enzyme Activation; Extracellular Matrix; Fibronectins; Heat-Shock Proteins; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pseudopodia; Swine; Thiazoles; Thiazolidines; Tunica Media | 2004 |
Effects of a new cystic fibrosis transmembrane conductance regulator inhibitor on Cl- conductance in human sweat ducts.
Topics: Benzoates; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Humans; In Vitro Techniques; Phosphorylation; Sodium Chloride; Sweat Glands; Thiazoles; Thiazolidines | 2004 |
Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets.
Topics: Actins; Animals; Antineoplastic Agents; Biological Transport; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium-Transporting ATPases; Cytochalasin D; Cytoskeleton; Depsipeptides; Enzyme Inhibitors; Humans; Hydroquinones; Nucleic Acid Synthesis Inhibitors; Peptides, Cyclic; ras Proteins; Signal Transduction; Thiazoles; Thiazolidines | 2004 |
Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Caco-2 Cells; Cell Line, Tumor; Cytochalasin D; Cytoskeleton; Enzyme Activation; Epithelial Cells; Gene Expression; HT29 Cells; Humans; I-kappa B Proteins; Inflammation; Interleukin-8; Intestines; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Thiazoles; Thiazolidines; Transcription, Genetic | 2004 |
Disruption of astral microtubule contact with the cell cortex activates a Bub1, Bub3, and Mad3-dependent checkpoint in fission yeast.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Chromatids; Cyclin B; Fungal Proteins; Kinetochores; Protein Kinases; Protein Serine-Threonine Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Securin; Spindle Apparatus; Thiazoles; Thiazolidines; Ubiquitin-Protein Ligase Complexes | 2004 |
Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Extracellular Matrix; Fibroblasts; Focal Adhesions; Humans; Integrin alphaVbeta3; Integrins; Male; Microscopy, Electron, Scanning; Microscopy, Video; Paxillin; Phosphoproteins; Phosphotyrosine; Rats; Stress Fibers; Stress, Mechanical; Thiazoles; Thiazolidines; Time Factors; Vinculin | 2004 |
Involvement of filamentous actin in setting the threshold for degranulation in mast cells.
Topics: Actins; Animals; Antigens, Surface; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Degranulation; Cell Line, Tumor; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Mast Cells; Membrane Glycoproteins; Membrane Proteins; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Aggregation; Receptors, IgE; Signal Transduction; Syk Kinase; Thiazoles; Thiazolidines; Thy-1 Antigens; Type C Phospholipases | 2004 |
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.
Topics: Activated-Leukocyte Cell Adhesion Molecule; Alkaloids; Antibodies, Monoclonal; Benzophenanthridines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Down-Regulation; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; K562 Cells; Microscopy, Fluorescence; Phenanthridines; Phosphorus Radioisotopes; Protein Kinase C; Protein Kinase C-alpha; Retroviridae; rho GTP-Binding Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 2004 |
Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Blotting, Western; Brain; Cell Count; Cell Death; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; MPTP Poisoning; PC12 Cells; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo.
Topics: Actins; Anions; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Membrane; Chloride Channels; Chlorides; Chlorine; Cytoskeletal Proteins; Cytoskeleton; Detergents; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Glutathione Transferase; Humans; Immunoblotting; In Vitro Techniques; Iodides; Ions; Liposomes; Microfilament Proteins; Microscopy, Fluorescence; Microvilli; Models, Biological; Octoxynol; Phosphoproteins; Placenta; Precipitin Tests; Protein Binding; Recombinant Fusion Proteins; Recombinant Proteins; Subcellular Fractions; Thiazoles; Thiazolidines; Transfection | 2004 |
Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Polarity; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dictyostelium; Fluorescence; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Thiazoles; Thiazolidines; Time Factors; Tumor Suppressor Proteins | 2004 |
Lipid raft polarization contributes to hyphal growth in Candida albicans.
Topics: Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Candida albicans; Cell Membrane; Cell Polarity; Ergosterol; Fatty Acids, Monounsaturated; Filipin; Hyphae; Ketoconazole; Membrane Microdomains; Sphingolipids; Sterols; Thiazoles; Thiazolidines | 2004 |
The promotion of gravitropism in Arabidopsis roots upon actin disruption is coupled with the extended alkalinization of the columella cytoplasm and a persistent lateral auxin gradient.
Topics: Actins; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Cytoplasm; Cytoskeleton; Gravitropism; Gravity Sensing; Hydrogen-Ion Concentration; Indoleacetic Acids; Kinetics; Plant Root Cap; Signal Transduction; Thiazoles; Thiazolidines | 2004 |
The exchanger inhibitory peptide region-dependent inhibition of Na+/Ca2+ exchange by SN-6 [2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative.
Topics: Adenosine Triphosphate; Animals; Benzyl Compounds; Cells, Cultured; Cricetinae; Cricetulus; Hypoxia; Kidney Diseases; Peptides; Protective Agents; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sodium-Calcium Exchanger; Thiazoles; Thiazolidines | 2004 |
A new dimension to the biosynthetic products isolated from the sponge Negombata magnifica.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Indian Ocean; Molecular Structure; Porifera; Pyrones; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2004 |
Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.
Topics: Acetylation; Actin Cytoskeleton; Actins; Acute-Phase Proteins; ADP Ribose Transferases; Amides; Animals; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Colforsin; Cytoskeleton; Focal Adhesions; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Mice; Microtubules; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Thiazoles; Thiazolidines; Tubulin | 2004 |
Cytokinesis in brown algae: studies of asymmetric division in fucoid zygotes.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cytokinesis; Cytoskeleton; Dinitrobenzenes; Phaeophyceae; Secretory Vesicles; Sulfanilamides; Thiazoles; Thiazolidines; Zygote | 2004 |
A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO.
Topics: Animals; Ascorbic Acid; Carbon; CD59 Antigens; Chromosomal Instability; Cricetinae; Cricetulus; Cysteine; Dimethyl Sulfoxide; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Linear Energy Transfer; Mutation; Radiation-Protective Agents; Thiazoles; Thiazolidines | 2004 |
The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2, but is dependent on an intact actin cytoskeleton as determined by FRAP.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Epithelial Cells; Green Fluorescent Proteins; Growth Substances; Kidney Tubules; Light; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Opossums; Phosphoproteins; Protein Structure, Tertiary; Protein Transport; Rabbits; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidines; Time Factors; Transfection | 2004 |
The influence of actin microfilaments on signaling by the receptor with high-affinity for IgE.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Degranulation; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme Precursors; Immunoglobulin E; Intracellular Signaling Peptides and Proteins; Mast Cells; Mice; Phosphorylation; Protein-Tyrosine Kinases; Receptors, IgE; src-Family Kinases; Syk Kinase; Temperature; Thiazoles; Thiazolidines | 2004 |
CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Benzoates; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Diuretics; Female; Glyburide; Hypoglycemic Agents; Male; Membrane Potentials; Mice; Mice, Inbred CFTR; Nasal Mucosa; Sus scrofa; Thiazoles; Thiazolidines | 2004 |
Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues.
Topics: Actins; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Light; Male; Microscopy, Confocal; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Muscles; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Time Factors; Wiskott-Aldrich Syndrome Protein, Neuronal | 2004 |
Modulation of acto-myosin contractility in skeletal muscle myoblasts uncouples growth arrest from differentiation.
Topics: Actomyosin; Animals; Antimetabolites; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Bromodeoxyuridine; Cell Adhesion; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Membrane; Cell Proliferation; Cell Separation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cytoskeleton; Diacetyl; DNA; Enzyme Inhibitors; Flow Cytometry; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Kinetics; Mice; Microscopy, Fluorescence; Muscle Contraction; Muscle, Skeletal; Muscles; Myosin Heavy Chains; Myosin-Light-Chain Kinase; Myosins; Naphthalenes; Polymers; Resting Phase, Cell Cycle; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transfection; Tumor Suppressor Proteins | 2004 |
Immune modulator pidotimod decreases the in vitro expression of CD30 in peripheral blood mononuclear cells of atopic asthmatic and normal children.
Topics: Asthma; Child; Child, Preschool; Cytokines; Down-Regulation; Female; Humans; Hypersensitivity; Immunologic Factors; Ki-1 Antigen; Leukocytes, Mononuclear; Male; Pyrrolidonecarboxylic Acid; T-Lymphocytes, Helper-Inducer; Thiazoles; Thiazolidines | 2004 |
The yeast dynamin-related GTPase Vps1p functions in the organization of the actin cytoskeleton via interaction with Sla1p.
Topics: Actins; Amino Acid Sequence; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cathepsin A; Cell Death; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Dynamins; Endocytosis; Genotype; GTP Phosphohydrolases; GTP-Binding Proteins; Immunoprecipitation; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; src Homology Domains; Temperature; Thiazoles; Thiazolidines; Time Factors; Vesicular Transport Proteins | 2004 |
Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Base Sequence; Butyrates; Carrier Proteins; Cloning, Molecular; COS Cells; DNA; Fatty Acid-Binding Proteins; Genes, Reporter; Humans; Mice; Phenylurea Compounds; PPAR gamma; Promoter Regions, Genetic; Thiazoles; Thiazolidines | 2004 |
Myosin II activity is required for severing-induced axon retraction in vitro.
Topics: Actins; Amides; Animals; Axons; Axotomy; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Growth Cones; Heterocyclic Compounds, 4 or More Rings; Immunohistochemistry; Microscopy, Video; Myosin Type II; Neurons; Organ Culture Techniques; Peptides; Pyridines; Retina; Retrograde Degeneration; Thiazoles; Thiazolidines; Time Factors; Tubulin | 2004 |
Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin.
Topics: Active Transport, Cell Nucleus; Amides; Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Division; Cells, Cultured; Cytochalasin D; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Oxadiazoles; Phosphoproteins; Phosphorylation; Piperazines; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Subunits; Protein Transport; Pulmonary Artery; Pyridines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Recombinant Fusion Proteins; rho-Associated Kinases; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Signal Transduction; Thiazoles; Thiazolidines; Transcription Factors | 2004 |
Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.
Topics: Actin Cytoskeleton; Adherens Junctions; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Claudin-1; Cytochalasin D; Dogs; Junctional Adhesion Molecules; Membrane Proteins; Microscopy, Fluorescence; Nectins; Occludin; Thiazoles; Thiazolidines; Tight Junctions | 2004 |
[Antioxidants-induced rearrangements of actin cytoskeleton in 3T3 and 3T3-SV40 fibroblasts].
Topics: 3T3 Cells; Acetylcysteine; Actin Cytoskeleton; Actins; Animals; Antioxidants; Cell Line, Transformed; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Simian virus 40; Stress Fibers; Thiazoles; Thiazolidines; Time Factors | 2004 |
Mobile actin clusters and traveling waves in cells recovering from actin depolymerization.
Topics: Actins; Adaptation, Physiological; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Dictyostelium; Molecular Motor Proteins; Multiprotein Complexes; Protein Binding; Protein Denaturation; Protein Folding; Pyridinium Compounds; Quaternary Ammonium Compounds; Thiazoles; Thiazolidines | 2004 |
Non-muscle myosin II and myosin light chain kinase are downstream targets for vasopressin signaling in the renal collecting duct.
Topics: Actins; Amino Acid Sequence; Animals; Aquaporin 2; Aquaporins; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Deamino Arginine Vasopressin; Depsipeptides; Electrophoresis, Gel, Two-Dimensional; Gizzard, Non-avian; Immunoblotting; Immunochemistry; Immunohistochemistry; Kidney Tubules, Collecting; Male; Mass Spectrometry; Molecular Sequence Data; Myosin Type II; Myosin-Light-Chain Kinase; Naphthalenes; Osmosis; Peptides; Perfusion; Phosphorylation; Protein Isoforms; Proteome; Rats; Rats, Sprague-Dawley; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Thiazolidines; Time Factors; Turkey; Vasopressins; Water | 2004 |
Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Cell Adhesion Molecules; Chemokines; Disease Models, Animal; Eosinophil Cationic Protein; Interleukins; Lung; Mice; NF-kappa B; Ovalbumin; Prodrugs; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines | 2004 |
Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction.
Topics: Actin Cytoskeleton; Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Phenylephrine; Polymers; Thiazoles; Thiazolidines; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Degradation and adsorption of fosthiazate in soil.
Topics: Adsorption; Antinematodal Agents; Half-Life; Hydrogen-Ion Concentration; Kinetics; Organophosphorus Compounds; Soil; Soil Microbiology; Thiazoles; Thiazolidines | 2004 |
Functional distinction between Cln1p and Cln2p cyclins in the control of the Saccharomyces cerevisiae mitotic cycle.
Topics: Blotting, Northern; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cyclins; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Immunoprecipitation; Mitosis; Mutation; S Phase; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2004 |
Xin repeats define a novel actin-binding motif.
Topics: Actins; Amino Acid Motifs; Amino Acid Sequence; beta Catenin; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; Cell Line; Cell Line, Tumor; Circular Dichroism; Cytoskeletal Proteins; DNA-Binding Proteins; Focal Adhesions; Humans; LIM Domain Proteins; Microscopy, Fluorescence; Molecular Sequence Data; Muscle, Skeletal; Mutation; Nuclear Proteins; Peptides; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Thiazoles; Thiazolidines; Trans-Activators; Transfection; Tropomyosin | 2004 |
Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons.
Topics: Actin Cytoskeleton; Actins; Amides; Animals; Axons; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cells, Cultured; Cytoskeleton; Dendrites; Hippocampus; Imatinib Mesylate; Microtubule-Associated Proteins; Neurons; Piperazines; Proto-Oncogene Proteins c-abl; Pyridines; Pyrimidines; rac1 GTP-Binding Protein; Rats; rho GTP-Binding Proteins; Signal Transduction; Thiazoles; Thiazolidines | 2004 |
Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle.
Topics: Acetylcholine; Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Depsipeptides; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Stress, Mechanical; Thiazoles; Thiazolidines; Trachea | 2005 |
Effect of low-dose latrunculin B on anterior segment physiologic features in the monkey eye.
Topics: Accommodation, Ocular; Administration, Topical; Animals; Anterior Chamber; Aqueous Humor; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cornea; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Male; Pilocarpine; Pupil; Sympatholytics; Thiazoles; Thiazolidines | 2004 |
The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors.
Topics: Animals; Benzoates; Cell Division; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Electric Conductivity; Epithelium; Genistein; Glyburide; Ion Transport; Kidney Diseases, Cystic; Nitrobenzoates; Thiazoles; Thiazolidines | 2004 |
L-2-oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products.
Topics: Cell Division; Cells, Cultured; Cytosol; Epithelial Cells; Epithelium; Glucose; Hemodialysis Solutions; Humans; Interleukin-6; L-Lactate Dehydrogenase; Peritoneal Cavity; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2004 |
Wave2 activates serum response element via its VCA region and functions downstream of Rac.
Topics: Actins; Amino Acid Sequence; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Mice; Microfilament Proteins; Mutation; rac GTP-Binding Proteins; Serum Response Element; Signal Transduction; Thiazoles; Thiazolidines; Transfection; Wiskott-Aldrich Syndrome Protein Family | 2004 |
Regulation of interleukin-6 expression by arecoline in human buccal mucosal fibroblasts is related to intracellular glutathione levels.
Topics: Areca; Arecoline; Buthionine Sulfoximine; Fibroblasts; Glutathione; Humans; Interleukin-6; Male; Oral Submucous Fibrosis; Polymerase Chain Reaction; Pyrrolidonecarboxylic Acid; RNA, Messenger; Thiazoles; Thiazolidines; Up-Regulation | 2004 |
Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells.
Topics: Actins; Amino Acid Transport Systems; Amino Acid Transport Systems, Basic; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cell Wall; Chromosomes; Cloning, Molecular; Cytoskeleton; Detergents; DNA; Fungal Proteins; Genotype; Green Fluorescent Proteins; Immunoblotting; Marine Toxins; Membrane Microdomains; Membrane Proteins; Nocodazole; Nucleotide Transport Proteins; Octoxynol; Plasmids; Protein Structure, Tertiary; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Time Factors | 2004 |
The nuclear kinase Lsk1p positively regulates the septation initiation network and promotes the successful completion of cytokinesis in response to perturbation of the actomyosin ring in Schizosaccharomyces pombe.
Topics: Actomyosin; Alleles; Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cell Nucleus; Cell Survival; Cyclin-Dependent Kinases; Cytokinesis; Dose-Response Relationship, Drug; Gene Deletion; Genotype; Green Fluorescent Proteins; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutation; Nuclear Proteins; Open Reading Frames; Phenotype; Phylogeny; Protein Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Signal Transduction; Temperature; Thiazoles; Thiazolidines; Time Factors | 2005 |
In vitro culture of Arabidopsis embryos within their ovules.
Topics: Arabidopsis; Biological Transport; Biomarkers; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Cytoskeleton; Dinitrobenzenes; Germination; Monensin; Seeds; Sulfanilamides; Thiazoles; Thiazolidines | 2004 |
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells.
Topics: Actins; Animals; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Movement; Cell Size; Cofilin 1; Cytokinesis; Destrin; Fibroblasts; Fibronectins; Fluorescein-5-isothiocyanate; Fluorescence Recovery After Photobleaching; Fluorescent Antibody Technique; Fluorescent Dyes; Gene Silencing; Indoles; Kinetics; Melanoma, Experimental; Mice; Microfilament Proteins; Microscopy, Video; NIH 3T3 Cells; Protein Isoforms; RNA, Small Interfering; Stress Fibers; Thiazoles; Thiazolidines | 2005 |
Structure and dynamics of the Golgi complex at 15 degrees C: low temperature induces the formation of Golgi-derived tubules.
Topics: Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Coat Protein Complex I; Galactosyltransferases; Golgi Apparatus; HeLa Cells; Humans; Microscopy, Confocal; Microscopy, Immunoelectron; Microtubules; Nocodazole; Protein Transport; Temperature; Thiazoles; Thiazolidines | 2005 |
[Characterization of SN-6, a novel exchange inhibitor and its renal protective effect].
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Benzyl Compounds; Calcium; Cells, Cultured; Cricetinae; Depression, Chemical; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Ischemia; Kidney Tubules; LLC-PK1 Cells; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium-Calcium Exchanger; Swine; Thiazoles; Thiazolidines | 2004 |
Modification of physicochemical properties of actin filaments suppresses cell fragmentation in the execution phase of staurosporine-induced apoptotic processes.
Topics: Actin Cytoskeleton; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspases; Cell Line, Tumor; Depsipeptides; Enzyme Inhibitors; Humans; Immunoblotting; Membrane Potentials; Microscopy, Confocal; Mitochondria; Staurosporine; Thiazoles; Thiazolidines | 2004 |
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cadherins; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line; Cell Separation; Cytoskeleton; Depsipeptides; Mice; rac GTP-Binding Proteins; Thiazoles; Thiazolidines; Time Factors | 2004 |
A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis.
Topics: 3T3 Cells; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Clathrin; Clathrin-Coated Vesicles; Cytoskeleton; Depsipeptides; Endocytosis; Fibroblasts; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Luminescent Proteins; Mice; Microscopy, Fluorescence; Models, Biological; Red Fluorescent Protein; Thiazoles; Thiazolidines | 2005 |
Improvement of the macrophage functions in prematurely ageing mice by a diet supplemented with thiolic antioxidants.
Topics: Acetylcysteine; Aging, Premature; Animals; Antioxidants; Chemotaxis; Diet; Female; Macrophages, Peritoneal; Maze Learning; Mice; Mice, Inbred ICR; Phagocytosis; Sulfhydryl Compounds; Superoxides; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha | 2004 |
Phosphatidylinositol-4,5-bisphosphate: actin dynamics and the regulation of ATP-dependent and -independent secretion.
Topics: Actins; Adenosine Triphosphate; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chromaffin Cells; Cytoskeleton; Human Growth Hormone; Humans; Phosphatidylinositol 4,5-Diphosphate; Protein Serine-Threonine Kinases; Thiazoles; Thiazolidines; Type C Phospholipases | 2005 |
Transport of neurofilaments in growing axons requires microtubules but not actin filaments.
Topics: Actin Cytoskeleton; Animals; Animals, Newborn; Axons; Bridged Bicyclo Compounds, Heterocyclic; Diagnostic Imaging; Fluorescent Antibody Technique; Green Fluorescent Proteins; Microtubules; Neurofilament Proteins; Neurons; Nocodazole; Protein Transport; Rats; Superior Cervical Ganglion; Thiazoles; Thiazolidines; Time Factors; Transfection; Vinblastine | 2005 |
XTH acts at the microfibril-matrix interface during cell elongation.
Topics: Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Cell Size; Cell Wall; Dinitrobenzenes; Glucans; Glycosyltransferases; Microfibrils; Nicotiana; Nitriles; Plant Roots; Sulfanilamides; Thiazoles; Thiazolidines | 2005 |
Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation.
Topics: Actins; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Chromones; Dipodomys; Dogs; Isoenzymes; Listeria monocytogenes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phospholipase C delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Thiazoles; Thiazolidines; Type C Phospholipases | 2005 |
The basolateral NHE1 Na+/H+ exchanger regulates transepithelial HCO3- absorption through actin cytoskeleton remodeling in renal thick ascending limb.
Topics: Absorption; Actins; Amiloride; Animals; Bicarbonates; Bridged Bicyclo Compounds, Heterocyclic; Colchicine; Depsipeptides; Epithelium; Loop of Henle; Male; Nerve Growth Factor; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solubility; Thiazoles; Thiazolidines | 2005 |
Involvement of actin and polarisome in morphological change during spore germination of Saccharomyces cerevisiae.
Topics: Actins; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Cell Wall; Microscopy, Electron; Microscopy, Fluorescence; Morphogenesis; Mutation; Protein Serine-Threonine Kinases; rho GTP-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spores, Fungal; Thiazoles; Thiazolidines | 2005 |
Studying cytolinker proteins.
Topics: Actins; Animals; Blotting, Far-Western; Bridged Bicyclo Compounds, Heterocyclic; COS Cells; Cytoskeletal Proteins; Humans; In Vitro Techniques; Microtubules; Nocodazole; Protein Binding; Recombinant Proteins; Staining and Labeling; Thiazoles; Thiazolidines; Transfection; Two-Hybrid System Techniques | 2004 |
Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth.
Topics: Actins; Adaptor Proteins, Signal Transducing; Alleles; Body Patterning; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein, Saccharomyces cerevisiae; Cell Lineage; Cell Membrane; Cell Proliferation; Exocytosis; Gene Expression Regulation, Fungal; Genotype; Green Fluorescent Proteins; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Immunoprecipitation; Kinetics; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Mutation; Protein Binding; rab GTP-Binding Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Temperature; Thiazoles; Thiazolidines; Tropomyosin; Vesicular Transport Proteins | 2005 |
Cell relaxation after electrodeformation: effect of latrunculin A on cytoskeletal actin.
Topics: Actins; Algorithms; Biomechanical Phenomena; Brassica; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeletal Proteins; Depsipeptides; Electrodes; Half-Life; Protoplasts; Spectrum Analysis; Thiazoles; Thiazolidines; Viscosity | 2005 |
Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae.
Topics: Actins; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Membrane; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor Proteins; Cytoplasm; Escherichia coli; Fungal Proteins; Genotype; Glutathione Transferase; Green Fluorescent Proteins; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Immunoblotting; Immunoprecipitation; MAP Kinase Signaling System; Microscopy, Fluorescence; Models, Biological; Models, Genetic; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Repressor Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Temperature; Thiazoles; Thiazolidines; Time Factors | 2005 |
Dynamic interactions of Fc gamma receptor IIB with filamin-bound SHIP1 amplify filamentous actin-dependent negative regulation of Fc epsilon receptor I signaling.
Topics: Actins; Animals; Antigens, CD; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Contractile Proteins; Down-Regulation; Filamins; Immunoglobulin E; Inositol Polyphosphate 5-Phosphatases; Mast Cells; Membrane Microdomains; Mice; Microfilament Proteins; Molecular Weight; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Protein Binding; Protein Isoforms; Rats; Receptor Aggregation; Receptors, IgE; Receptors, IgG; Resting Phase, Cell Cycle; Signal Transduction; Thiazoles; Thiazolidines; Time Factors | 2005 |
Exploring the binding site structure of the PPAR gamma ligand-binding domain by computational solvent mapping.
Topics: Alkanesulfonates; Binding Sites; Cinnamates; Computational Biology; Humans; Ligands; Oxazines; Oxazoles; Phenylpropionates; PPAR gamma; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Rosiglitazone; Solvents; Thiazoles; Thiazolidinediones; Thiazolidines; Tyrosine | 2005 |
Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae.
Topics: Actin Cytoskeleton; Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Antigens, Viral, Tumor; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; Caveolae; Caveolin 1; Caveolin 2; Caveolins; Cell Line; Cell Line, Tumor; Cholesterol; Clathrin; Detergents; Dynamin II; Embryo, Mammalian; Endocytosis; Endoplasmic Reticulum, Smooth; Fibroblasts; Gene Expression; Genistein; Humans; Intracellular Signaling Peptides and Proteins; Membrane Microdomains; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Microtubules; Nocodazole; Phosphoproteins; Semliki forest virus; Simian virus 40; Thiazoles; Thiazolidines; Transferrin; Transport Vesicles; Tubulin; Vesicular Transport Proteins | 2005 |
The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion.
Topics: Actins; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Degranulation; Cytochalasins; Cytoplasmic Granules; Cytoskeleton; Humans; Kinetics; Microscopy, Electron, Transmission; Peptide Fragments; SNARE Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2005 |
Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniques.
Topics: Actins; Animals; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; CHO Cells; Colloids; Cricetinae; Diffusion; Green Fluorescent Proteins; Kidney; Membrane Proteins; Microscopy, Video; Models, Biological; Models, Molecular; Models, Statistical; Rats; Receptors, G-Protein-Coupled; Temperature; Thiazoles; Thiazolidines; Time Factors | 2005 |
Disruption of the filamentous actin cytoskeleton is necessary for the activation of capacitative calcium entry in naive smooth muscle cells.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cytochalasin D; Depsipeptides; Gallbladder; Guinea Pigs; Ion Transport; Male; Muscle, Smooth; Thiazoles; Thiazolidines | 2005 |
Concentric zones of active RhoA and Cdc42 around single cell wounds.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cardiac Myosins; cdc42 GTP-Binding Protein; Cytochalasin D; Cytoskeleton; Female; Intracellular Signaling Peptides and Proteins; Kinetics; Lasers; Luminescent Proteins; Microinjections; Microscopy, Fluorescence; Microtubules; Models, Biological; Myosin Light Chains; Nerve Tissue Proteins; Nocodazole; Oocytes; Paclitaxel; Phosphorylation; rhoA GTP-Binding Protein; RNA, Messenger; Thiazoles; Thiazolidines; Toxins, Biological; Wiskott-Aldrich Syndrome Protein, Neuronal; Xenopus | 2005 |
Amyloplasts and vacuolar membrane dynamics in the living graviperceptive cell of the Arabidopsis inflorescence stem.
Topics: Actins; Arabidopsis; Bridged Bicyclo Compounds, Heterocyclic; Flowers; Gravitropism; Gravity Sensing; Green Fluorescent Proteins; Microscopy, Electron; Microscopy, Fluorescence; Plant Stems; Plants, Genetically Modified; Plastids; Reaction Time; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Vacuoles | 2005 |
Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells.
Topics: Actin Cytoskeleton; Actins; Animals; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels; Calcium Signaling; Cell Membrane; Cytoskeleton; Detergents; Electrophysiology; Gelsolin; Green Fluorescent Proteins; Immunohistochemistry; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Male; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Pancreas; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidines | 2005 |
Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Drinking; Drug Therapy, Combination; Drug Tolerance; Eating; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Obesity; Pentanoic Acids; Rats; Rats, Zucker; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors | 2005 |
Actin filaments play a critical role in vacuolar trafficking at the Golgi complex in plant cells.
Topics: Actins; Arabidopsis; Arabidopsis Proteins; Base Sequence; Biological Transport, Active; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; DNA, Plant; Endoplasmic Reticulum; Genes, Plant; Golgi Apparatus; Mutation; Plants, Genetically Modified; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Vacuoles | 2005 |
Expression of constitutively active Akt/protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton.
Topics: 3T3 Cells; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Gene Expression Regulation, Enzymologic; Glucose Transporter Type 4; Insulin; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiazoles; Thiazolidines | 2005 |
Trafficking of a ligand-receptor complex on the growth cones as an essential step for the uptake of nerve growth factor at the distal end of the axon: a single-molecule analysis.
Topics: Animals; Axons; Bridged Bicyclo Compounds, Heterocyclic; Carbocyanines; Cells, Cultured; Chick Embryo; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Ganglia, Spinal; Growth Cones; Models, Biological; Nerve Growth Factor; Neurons; Protein Transport; Pseudopodia; Thiazoles; Thiazolidines; Time Factors | 2005 |
Effects of latrunculin B on outflow facility, intraocular pressure, corneal thickness, and miotic and accommodative responses to pilocarpine in monkeys.
Topics: Accommodation, Ocular; Administration, Topical; Animals; Anterior Eye Segment; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Cornea; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Macaca fascicularis; Male; Meiosis; Miotics; Pilocarpine; Pupil; Thiazoles; Thiazolidines | 2004 |
Phosphorylated MARCKS: a novel centrosome component that also defines a peripheral subdomain of the cortical actin cap in mouse eggs.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Centrosome; Cytoskeleton; Female; Intracellular Signaling Peptides and Proteins; Isoenzymes; Meiosis; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Oocytes; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Spindle Apparatus; Thiazoles; Thiazolidines; Tubulin | 2005 |
CFTR-regulated chloride transport at the ocular surface in living mice measured by potential differences.
Topics: Amiloride; Animals; Benzoates; Chlorides; Colforsin; Conjunctiva; Cornea; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Ion Transport; Membrane Potentials; Mice; Mice, Inbred CFTR; Mice, Mutant Strains; Thiazoles; Thiazolidines | 2005 |
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex.
Topics: Actins; Adherens Junctions; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cell Line; Cell Polarity; Epithelial Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Mucosa; Microvilli; Models, Biological; Molecular Motor Proteins; Myosin Type II; Polymers; Propanolamines; Thiazoles; Thiazolidines; Tight Junctions | 2005 |
Mto2p, a novel fission yeast protein required for cytoplasmic microtubule organization and anchoring of the cytokinetic actin ring.
Topics: Actins; Anaphase; Antibodies, Monoclonal; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Fungal Proteins; Gene Deletion; Green Fluorescent Proteins; GTP-Binding Proteins; Indoles; Microscopy, Fluorescence; Microscopy, Video; Microtubule-Associated Proteins; Microtubule-Organizing Center; Microtubules; Recombinant Fusion Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus; Thiazoles; Thiazolidines; Tubulin | 2005 |
[Monitoring of the residue of fosthiazate in water samples using solid-phase extraction coupled with gas chromatography/mass spectrometry].
Topics: Gas Chromatography-Mass Spectrometry; Organophosphorus Compounds; Pesticides; Sensitivity and Specificity; Thiazoles; Thiazolidines; Water Pollutants, Chemical; Water Supply | 2004 |
Directed motility of phagosomes in Tetrahymena thermophila requires actin and Myo1p, a novel unconventional myosin.
Topics: Actins; Animals; Animals, Genetically Modified; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Microscopy, Confocal; Microspheres; Myosin Heavy Chains; Nocodazole; Phagosomes; Protozoan Proteins; Recombinant Fusion Proteins; Tetrahymena thermophila; Thiazoles; Thiazolidines | 2005 |
[Actin polymerization kinetics in living cells disclosed by single-molecule speckle microscopy].
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cytochalasin D; Cytoskeletal Proteins; Cytoskeleton; Kinetics; Leukocytes; Microscopy, Fluorescence; Models, Biological; Thiazoles; Thiazolidines | 2005 |
Dissection of keratin dynamics: different contributions of the actin and microtubule systems.
Topics: Actin Cytoskeleton; Actins; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Genes, Reporter; Humans; Keratins; Microscopy, Fluorescence; Microtubules; Nocodazole; Protein Transport; Recombinant Fusion Proteins; Thiazoles; Thiazolidines | 2005 |
End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe.
Topics: Actins; Antifungal Agents; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Cycle; Cell Membrane; Cell Proliferation; Cytoskeletal Proteins; Endocytosis; Fungal Proteins; Genotype; Green Fluorescent Proteins; Microfilament Proteins; Microscopy, Fluorescence; Microtubule-Associated Proteins; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Temperature; Thiazoles; Thiazolidines | 2005 |
Microtubules are dispensable for the initial pathogenic development but required for long-distance hyphal growth in the corn smut fungus Ustilago maydis.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Cell Polarity; Cytoskeleton; Fluorescent Dyes; Hyphae; Indoles; Kinetics; Microtubules; Models, Biological; Pheromones; Thiazoles; Thiazolidines; Ustilago; Zea mays | 2005 |
Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Cytoskeleton; Humans; Ion Channels; K562 Cells; Leukemia; Microtubules; Thiazoles; Thiazolidines | 2005 |
Concise and practical synthesis of latrunculin a by ring-closing enyne-yne metathesis.
Topics: Alkynes; Bridged Bicyclo Compounds, Heterocyclic; Cyclization; Molecular Structure; Thiazoles; Thiazolidines | 2005 |
Involvement of actin in agonist-induced endocytosis of the G protein-coupled receptor for thromboxane A2: overcoming of actin disruption by arrestin-3 but not arrestin-2.
Topics: Actins; Antineoplastic Agents; Arrestins; Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Line; Clathrin; Cloning, Molecular; Colchicine; Cytochalasin D; Cytoskeleton; Depsipeptides; Endocytosis; Enzyme-Linked Immunosorbent Assay; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Marine Toxins; Microscopy, Fluorescence; Nucleic Acid Synthesis Inhibitors; Phosphoproteins; Plasmids; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Thromboxane A2, Prostaglandin H2; rhoA GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines; Time Factors; Transfection | 2005 |
Actin polymerization promotes the reversal of streaming in the apex of pollen tubes.
Topics: Actin Cytoskeleton; Actins; Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cell Movement; Cell Polarity; Cytochalasin D; Cytoplasm; Cytoplasmic Streaming; Deoxyribonucleases; Depsipeptides; Flowers; Germination; Lilium; Nucleic Acid Synthesis Inhibitors; Pollen; Polymers; Reproduction; Thiazoles; Thiazolidines | 2005 |
Live-cell imaging of tubulin in the filamentous fungus Magnaporthe grisea treated with anti-microtubule and anti-microfilament agents.
Topics: Actin Cytoskeleton; Antifungal Agents; Bacterial Proteins; Benomyl; Bridged Bicyclo Compounds, Heterocyclic; Fungicides, Industrial; Griseofulvin; Luminescent Proteins; Magnaporthe; Microscopy, Electron; Microtubules; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Transformation, Genetic; Tubulin | 2005 |
Effect of prolyl endopeptidase inhibition on arginine-vasopressin and thyrotrophin-releasing hormone catabolism in the rat brain.
Topics: Amygdala; Animals; Arginine Vasopressin; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Administration Schedule; Hippocampus; In Vitro Techniques; Indoles; Male; Nootropic Agents; Protease Inhibitors; Rats; Rats, Wistar; Serine Endopeptidases; Thiazoles; Thiazolidines; Thyrotropin-Releasing Hormone | 2005 |
Uptake of LPS/E. coli/latex beads via distinct signalling pathways in medfly hemocytes: the role of MAP kinases activation and protein secretion.
Topics: Actin Cytoskeleton; Animals; Bridged Bicyclo Compounds, Heterocyclic; Ceratitis capitata; Cytochalasin D; Enzyme Inhibitors; Escherichia coli; Hemocytes; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Microspheres; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Phosphorylation; Polyenes; Polyunsaturated Alkamides; Protein Transport; Thiazoles; Thiazolidines | 2005 |
Role of coagulation factor Xa and protease-activated receptor 2 in human mesangial cell proliferation.
Topics: Benzamides; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Factor Xa; Glomerular Mesangium; Humans; Naphthalenes; Propionates; Receptor, PAR-1; Receptor, PAR-2; Thiazoles; Thiazolidines | 2005 |
Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex.
Topics: Animals; Animals, Newborn; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chelating Agents; Cytochalasin D; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neuregulin-1; Neurons; Nucleic Acid Synthesis Inhibitors; Patch-Clamp Techniques; Prefrontal Cortex; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Thiazoles; Thiazolidines | 2005 |
Role of the septin ring in the asymmetric localization of proteins at the mother-bud neck in Saccharomyces cerevisiae.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle Proteins; Cell Polarity; Cyclin-Dependent Kinases; Cytokinesis; Cytoskeletal Proteins; Mutation; Profilins; Protein Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines | 2005 |
Non-equilibration of hydrostatic pressure in blebbing cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Surface Extensions; Cytoplasm; Cytoskeleton; Elasticity; Hydrostatic Pressure; Microscopy, Video; Models, Biological; Movement; Perfusion; Staurosporine; Thiazoles; Thiazolidines; Time Factors | 2005 |
A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats.
Topics: Animals; Benzoates; Bicarbonates; Chromatography, High Pressure Liquid; Cystamine; Cystic Fibrosis Transmembrane Conductance Regulator; Duodenal Ulcer; Duodenum; Gastric Acid; Male; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Thiazoles; Thiazolidines | 2005 |
Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cells.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Clathrin-Coated Vesicles; Coated Pits, Cell-Membrane; Cortactin; Endocytosis; Mice; Microfilament Proteins; Microscopy, Fluorescence; Microscopy, Video; Polymers; Swiss 3T3 Cells; Thiazoles; Thiazolidines | 2005 |
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines | 2005 |
Diverted total synthesis: preparation of a focused library of latrunculin analogues and evaluation of their actin-binding properties.
Topics: Actin Cytoskeleton; Actins; Alkynes; Animals; Bridged Bicyclo Compounds, Heterocyclic; Hydrogen Bonding; Ligands; Mice; Models, Molecular; Molecular Structure; NIH 3T3 Cells; Protein Binding; Thiazoles; Thiazolidines | 2005 |
Analysis of tissue flow patterns during primitive streak formation in the chick embryo.
Topics: Actins; Animals; Aphidicolin; Bridged Bicyclo Compounds, Heterocyclic; Bromodeoxyuridine; Carbocyanines; Cell Division; Cell Movement; Chick Embryo; Embryonic Development; Gastrula; Immunohistochemistry; Microscopy, Fluorescence; Thiazoles; Thiazolidines | 2005 |
Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes.
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Glutathione; Indicators and Reagents; Mercury Poisoning, Nervous System; Methylmercury Compounds; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2005 |
Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolae; Cell Line; Cholesterol; Clathrin-Coated Vesicles; Dogs; Dynamin II; Endocytosis; Genes, Reporter; Membrane Proteins; Occludin; Protein Transport; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Tight Junctions | 2005 |
Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.
Topics: Actins; Adaptor Proteins, Signal Transducing; Bridged Bicyclo Compounds, Heterocyclic; Cell Polarity; Microfilament Proteins; Mitogen-Activated Protein Kinases; Myosin Heavy Chains; Myosin Type V; Pheromones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Thiazoles; Thiazolidines | 2005 |
Factors affecting the efficacy of non-fumigant nematicides for controlling root-knot nematodes.
Topics: Animals; Carbamates; Larva; Nematoda; Organophosphorus Compounds; Organothiophosphorus Compounds; Ovum; Pesticide Residues; Pesticides; Seedlings; Soil; Solanum lycopersicum; Thiazoles; Thiazolidines | 2005 |
Role of actin polymerization in bending of the early heart tube.
Topics: Abnormalities, Drug-Induced; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Cytochalasin D; Heart; Heart Defects, Congenital; Microscopy, Confocal; Myocardium; Thiazoles; Thiazolidines | 2005 |
In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast.
Topics: Actins; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Membrane; Clathrin; Cytoskeletal Proteins; Cytoskeleton; Endocytosis; Endosomes; Microfilament Proteins; Microscopy, Fluorescence; Monomeric Clathrin Assembly Proteins; Mutation; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidines; Transcription Factors; Vesicular Transport Proteins | 2005 |
Characterization of the activities of actin-affecting drugs on tumor cell migration.
Topics: Actins; Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cytochalasin D; Cytoskeleton; Depsipeptides; Humans; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Invasiveness; Statistics, Nonparametric; Thiazoles; Thiazolidines | 2006 |
The 4.1 protein coracle mediates subunit-selective anchoring of Drosophila glutamate receptors to the postsynaptic actin cytoskeleton.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drosophila melanogaster; Drosophila Proteins; Larva; Membrane Proteins; Mutation; Neuromuscular Junction; Patch-Clamp Techniques; Protein Interaction Mapping; Protein Structure, Tertiary; Receptors, Glutamate; Thiazoles; Thiazolidines; Two-Hybrid System Techniques | 2005 |
A contractile nuclear actin network drives chromosome congression in oocytes.
Topics: Actins; Animals; Biological Transport; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Chromosome Segregation; Chromosomes; Meiosis; Microscopy, Confocal; Microtubules; Nocodazole; Oocytes; Species Specificity; Starfish; Thiazoles; Thiazolidines | 2005 |
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells.
Topics: Anthracenes; Apoptosis; Caspases; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Enzyme Activation; HCT116 Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Thiazoles; Thiazolidines | 2005 |
Enantiorecognition on solid chiral selectors using microbatch technology: an example of limitation in case of strong association in the racemate.
Topics: Adsorption; Cyclohexylamines; Models, Molecular; Molecular Conformation; Salicylates; Stereoisomerism; Thiazoles; Thiazolidines | 2005 |
Seizures induced by microperfusion of glutamate and glycine in the hippocampus of rats pretreated with latrunculin A.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Dizocilpine Maleate; Drug Interactions; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thiazoles; Thiazolidines | 2005 |
Biological monitoring of carbon disulphide and phthalate exposure in the contemporary rubber industry.
Topics: Air Pollutants, Occupational; Carbon Disulfide; Environmental Monitoring; Half-Life; Humans; Industry; Male; Occupational Exposure; Phthalic Acids; Reference Values; Rubber; Thiazoles; Thiazolidines | 2005 |
Role of fission yeast myosin I in organization of sterol-rich membrane domains.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Endocytosis; Filipin; Green Fluorescent Proteins; Membrane Microdomains; Microscopy, Confocal; Models, Biological; Mutation; Myosin Type I; Protein Structure, Tertiary; Schizosaccharomyces; Thiazoles; Thiazolidines | 2005 |
Thioproline prevents carcinogenesis in the remnant stomach induced by duodenal reflux.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Duodenum; Gastric Mucosa; Male; Models, Anatomic; Nitrites; Rats; Rats, Wistar; Stomach Neoplasms; Thiazoles; Thiazolidines | 2006 |
Latrunculin B effects on trabecular meshwork and corneal endothelial morphology in monkeys.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Endothelium, Corneal; Intraocular Pressure; Macaca fascicularis; Marine Toxins; Microscopy, Electron; Porifera; Thiazoles; Thiazolidines; Trabecular Meshwork | 2006 |
The mRNA for elongation factor 1alpha is localized in dendrites and translated in response to treatments that induce long-term depression.
Topics: Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Dendrites; Dentate Gyrus; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Neurons; Peptide Elongation Factor 1; Protein Synthesis Inhibitors; Rats; Receptors, Metabotropic Glutamate; RNA, Messenger; Synapses; Thiazoles; Thiazolidines; Tissue Distribution | 2005 |
Differential effects of Latrunculin-A on myofibrils in cultures of skeletal muscle cells: insights into mechanisms of myofibrillogenesis.
Topics: Actinin; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; CapZ Actin Capping Protein; Cells, Cultured; Green Fluorescent Proteins; Microfilament Proteins; Muscle Proteins; Muscle, Skeletal; Myofibrils; Quail; Thiazoles; Thiazolidines; Transfection | 2005 |
Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Benzoates; Cells, Cultured; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Genistein; Glyburide; In Vitro Techniques; Isoproterenol; Mice; Mice, Inbred CFTR; Muscle, Smooth, Vascular; ortho-Aminobenzoates; Quinolizines; Serotonin; Thiazoles; Thiazolidines; Vasoactive Intestinal Peptide; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Neutrophil-bead collision assay: pharmacologically induced changes in membrane mechanics regulate the PSGL-1/P-selectin adhesion lifetime.
Topics: Actins; beta-Cyclodextrins; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Membrane; Cell Movement; Cholesterol; Cytochalasin D; Depsipeptides; Formaldehyde; Humans; Kinetics; Mechanics; Membrane Glycoproteins; Microscopy, Atomic Force; Microspheres; Models, Statistical; Monte Carlo Method; Neutrophils; P-Selectin; Protein Binding; Selectins; Stress, Mechanical; Thiazoles; Thiazolidines | 2005 |
Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy.
Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Algorithms; Animals; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Movement; Cells, Cultured; Depsipeptides; Epithelial Cells; Image Processing, Computer-Assisted; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Models, Molecular; Models, Statistical; Polymers; Potoroidae; Pseudopodia; Thiazoles; Thiazolidines; Time Factors | 2005 |
A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma.
Topics: Animals; Asthma; Capillary Permeability; Female; Mice; Mice, Inbred BALB C; Ovalbumin; Phosphatidylinositol 3-Kinases; Phosphorylation; Prodrugs; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines; Thioctic Acid; Vascular Endothelial Growth Factor A | 2005 |
Rat airway smooth muscle cell during actin modulation: rheology and glassy dynamics.
Topics: Actins; Animals; Azepines; Biomechanical Phenomena; Bridged Bicyclo Compounds, Heterocyclic; Bucladesine; Cells, Cultured; Cross-Linking Reagents; Cytochalasin D; Genistein; Muscle Contraction; Myocytes, Smooth Muscle; Myosins; Naphthalenes; Peptides, Cyclic; Phalloidine; Rats; Rheology; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Thiazolidines; Trachea | 2005 |
Inhibitors of actin polymerisation stimulate arachidonic acid release and 5-lipoxygenase activation by upregulation of Ca2+ mobilisation in polymorphonuclear leukocytes involving Src family kinases.
Topics: Actins; Adult; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cytochalasin D; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleic Acid Synthesis Inhibitors; Polymers; src-Family Kinases; Thapsigargin; Thiazoles; Thiazolidines; Up-Regulation | 2005 |
Effect of cytoskeleton disruptors on L-type Ca channel distribution in rat ventricular myocytes.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channels, L-Type; Cells, Cultured; Colchicine; Cycloheximide; Cytochalasin D; Cytoskeletal Proteins; Heart Ventricles; Immunohistochemistry; Male; Microtubules; Myocytes, Cardiac; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Tubulin | 2005 |
Cyclase-associated protein is essential for the functioning of the endo-lysosomal system and provides a link to the actin cytoskeleton.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cation Transport Proteins; Cell Cycle Proteins; Cell Shape; Cytochalasins; Cytoskeleton; Dictyostelium; Endocytosis; Endosomes; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Intracellular Membranes; Lysosomes; Protozoan Proteins; Recombinant Fusion Proteins; Thiazoles; Thiazolidines; Vacuolar Proton-Translocating ATPases; Water-Electrolyte Balance | 2005 |
Brassinosteroids stimulate plant tropisms through modulation of polar auxin transport in Brassica and Arabidopsis.
Topics: Actins; Arabidopsis; Arabidopsis Proteins; Brassica; Brassinosteroids; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cholestanols; Gene Expression Regulation, Plant; GTP Phosphohydrolases; GTP-Binding Proteins; Indoleacetic Acids; Mutation; Plant Growth Regulators; Plant Roots; Steroids, Heterocyclic; Thiazoles; Thiazolidines; Tropism | 2005 |
Nebulin regulates the assembly and lengths of the thin filaments in striated muscle.
Topics: Acetates; Actins; Animals; Antibodies, Monoclonal; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Gene Expression Regulation, Developmental; Microscopy, Fluorescence; Muscle Development; Muscle Proteins; Muscle, Skeletal; Myoblasts; Myocytes, Cardiac; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Thiazoles; Thiazolidines; Transfection; Xanthenes | 2005 |
Leptin-induced dynamic alterations in the actin cytoskeleton mediate the activation and synaptic clustering of BK channels.
Topics: Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cytochalasin D; Cytoskeleton; Depsipeptides; Electrophysiology; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Large-Conductance Calcium-Activated Potassium Channels; Leptin; Magnesium; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Neurons; Nocodazole; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Porifera; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Synapses; Thiazoles; Thiazolidines; Time Factors; Tubulin Modulators | 2005 |
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
Topics: Aniline Compounds; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Colonic Neoplasms; Enzyme Activation; Humans; Lung Neoplasms; Microtubules; Mitogen-Activated Protein Kinase 8; Mitosis; Spindle Apparatus; Thiazoles; Thiazolidines | 2005 |
Rapid WAVE dynamics in dendritic spines of cultured hippocampal neurons is mediated by actin polymerization.
Topics: 2-Amino-5-phosphonovalerate; Actins; Anesthetics, Local; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cell Size; Cell Surface Extensions; Cells, Cultured; Dendritic Spines; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Mice; Microscopy, Confocal; Mutagenesis; Neurons; Phalloidine; Quinoxalines; Tetrodotoxin; Thiazoles; Thiazolidines; Time Factors; Transfection; Wiskott-Aldrich Syndrome Protein Family | 2005 |
Enantioselective synthesis of apoptolidinone: exploiting the versatility of thiazolidinethione chiral auxiliaries.
Topics: Macrolides; Molecular Structure; Pyrones; Stereoisomerism; Thiazoles; Thiazolidines | 2005 |
Photoactivation of GFP reveals protein dynamics within the endoplasmic reticulum membrane.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Endoplasmic Reticulum; Golgi Apparatus; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Intracellular Membranes; Membrane Fluidity; Membrane Proteins; Movement; Nicotiana; Photochemistry; Software; Thiazoles; Thiazolidines | 2006 |
Height changes associated with pigment aggregation in Xenopus laevis melanophores.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Shape; Cells, Cultured; Electrophysiology; Melanophores; Melanosomes; Melatonin; Microtubules; Pigments, Biological; Thiazoles; Thiazolidines; Xenopus laevis | 2004 |
Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1-dependent functions.
Topics: Adolescent; Adult; Cell Adhesion; Cell Degranulation; Cell Movement; Cells, Cultured; Endothelium, Vascular; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Humans; In Vitro Techniques; Integrin alpha4beta1; Intercellular Adhesion Molecule-1; Male; Middle Aged; Pyrazoles; Superoxides; Thiazoles; Thiazolidines; Vascular Cell Adhesion Molecule-1 | 2005 |
Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells.
Topics: Actin Cytoskeleton; Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Diacetyl; Epithelial Cells; Exocytosis; Eye Proteins; Female; Fluorescence Recovery After Photobleaching; Lacrimal Apparatus; Membrane Proteins; Microscopy, Confocal; Naphthalenes; Nonmuscle Myosin Type IIA; Rabbits; Recombinant Fusion Proteins; Secretory Vesicles; Thiazoles; Thiazolidines | 2005 |
Effect of latrunculin B on intraocular pressure in the monkey eye.
Topics: Animals; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Cornea; Intraocular Pressure; Macaca fascicularis; Thiazoles; Thiazolidines | 2005 |
Stimulation of regulatory volume decrease (RVD) by isolated bovine articular chondrocytes following F-actin disruption using latrunculin B.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cartilage, Articular; Cattle; Cell Size; Cells, Cultured; Chondrocytes; Cytoskeleton; Lipoxygenase Inhibitors; Mechanotransduction, Cellular; Microscopy, Confocal; Microscopy, Fluorescence; Osmosis; Quinolines; Stimulation, Chemical; Thiazoles; Thiazolidines | 2005 |
Endocytosis and vesicle trafficking during tip growth of root hairs.
Topics: Arabidopsis; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Endocytosis; Endoplasmic Reticulum; Microscopy, Fluorescence; Plant Physiological Phenomena; Plant Roots; Thiazoles; Thiazolidines; Transport Vesicles; Triticum | 2005 |
A role for cytoskeletal elements in the light-driven translocation of proteins in rod photoreceptors.
Topics: Actin Cytoskeleton; Animals; Animals, Genetically Modified; Arrestin; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Green Fluorescent Proteins; Light; Microscopy, Confocal; Microtubules; Protein Transport; Recombinant Fusion Proteins; Retinal Rod Photoreceptor Cells; Thiabendazole; Thiazoles; Thiazolidines; Transducin; Xenopus laevis | 2005 |
Rho kinase regulates fragmentation and phagocytosis of apoptotic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Amides; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspase Inhibitors; Caspases; Cell Membrane; Chlorocebus aethiops; COS Cells; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Intracellular Signaling Peptides and Proteins; Marine Toxins; Muscle Contraction; Myosins; PC12 Cells; Phagocytosis; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Rats; rho-Associated Kinases; RNA, Small Interfering; Thiazoles; Thiazolidines | 2006 |
Conformation-specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm.
Topics: Actin Cytoskeleton; Actins; Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antibody Specificity; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Nucleus; Cytoplasm; Epitopes; Fibroblasts; HeLa Cells; Humans; Marine Toxins; Mice; Microscopy, Fluorescence; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Rabbits; Rats; Thiazoles; Thiazolidines; Vaccination | 2005 |
Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Male; Neovascularization, Pathologic; Phosphorylation; Prostatic Neoplasms; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2006 |
Actin is not an essential component in the mechanism of calcium-triggered vesicle fusion.
Topics: Actin Depolymerizing Factors; Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Depsipeptides; Exocytosis; Membrane Fusion; Secretory Vesicles; Strongylocentrotus purpuratus; Thiazoles; Thiazolidines | 2006 |
Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization.
Topics: Actin Cytoskeleton; Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Cell Survival; Cytochalasin D; Dexamethasone; Drug Interactions; Hormone Antagonists; Mesangial Cells; Mice; Mifepristone; NIH 3T3 Cells; Nucleic Acid Synthesis Inhibitors; Podocytes; Polymers; Puromycin Aminonucleoside; rho GTP-Binding Proteins; Thiazoles; Thiazolidines | 2005 |
Preparation of a clay-modified carbon paste electrode based on 2-thiazoline-2-thiol-hexadecylammonium sorption for the sensitive determination of mercury.
Topics: Adsorption; Aluminum Silicates; Anions; Bentonite; Calibration; Carbon; Cations, Divalent; Cetrimonium; Cetrimonium Compounds; Clay; Electrochemistry; Fresh Water; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Mercury; Oxidation-Reduction; Reproducibility of Results; Seawater; Thiazoles; Thiazolidines; X-Ray Diffraction | 2005 |
Efficient microwave enhanced regioselective synthesis of a series of benzimidazolyl/triazolyl spiro [indole-thiazolidinones] as potent antifungal agents and crystal structure of spiro[3H-indole-3,2'-thiazolidine]-3'(1,2,4-triazol-3-yl)-2,4'(1H)-dione.
Topics: Antifungal Agents; Benzimidazoles; Colletotrichum; Crystallization; Fusarium; Indoles; Microwaves; Models, Molecular; Molecular Structure; Rhizoctonia; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines; Triazoles; X-Ray Diffraction | 2006 |
2-Mercaptothiazoline modified mesoporous silica for mercury removal from aqueous media.
Topics: Adsorption; Magnetic Resonance Spectroscopy; Mercury; Molecular Structure; Nitrogen; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Temperature; Thiazoles; Thiazolidines; Water; X-Ray Diffraction | 2006 |
Change in the shape and density of dendritic spines caused by overexpression of acidic calponin in cultured hippocampal neurons.
Topics: Actins; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; Calponins; Cells, Cultured; CHO Cells; Cricetinae; Dendritic Spines; DNA, Complementary; Fluorescent Antibody Technique; Gene Expression; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Microfilament Proteins; Neurons; Rats; Rats, Wistar; Synapses; Thiazoles; Thiazolidines; Transfection | 2006 |
Impact of cis-proline analogs on peptide conformation.
Topics: Binding Sites; Biopolymers; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Models, Statistical; Models, Theoretical; Molecular Conformation; Nitrogen; Normal Distribution; Peptides; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Temperature; Tetrazoles; Thermodynamics; Thiazoles; Thiazolidines | 2006 |
Glutamate-induced Ca2+ influx in third-order neurons of salamander retina is regulated by the actin cytoskeleton.
Topics: Actins; Ambystoma; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Cytochalasin D; Cytoskeleton; Data Interpretation, Statistical; Depsipeptides; Glutamic Acid; In Vitro Techniques; Microscopy, Confocal; Receptors, Glutamate; Retina; Retinal Ganglion Cells; Thiazoles; Thiazolidines | 2006 |
HPLC determination of acetaminophen in saliva based on precolumn fluorescence derivatization with 12-(3,5-dichloro-2,4,6-triazinyl)benzo[d]benzo[1',2'-6,5]isoindolo[1,2-b][1,3]thiazolidine.
Topics: Acetaminophen; Chromatography, High Pressure Liquid; Fluorescence; Humans; Indoles; Isoindoles; Male; Middle Aged; Saliva; Thiazoles; Thiazolidines | 2005 |
The state of the actin cytoskeleton determines its association with gephyrin: role of ena/VASP family members.
Topics: Actin Cytoskeleton; Actins; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin D; Cytoskeleton; Depsipeptides; Hippocampus; Humans; Membrane Proteins; Microfilament Proteins; Neurons; Nucleic Acid Synthesis Inhibitors; Phosphoproteins; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Synapses; Thiazoles; Thiazolidines | 2006 |
The onset of gravisensitivity in the embryonic root of flax.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Flax; Germination; Gravitropism; Gravity Sensing; Plant Roots; Rotation; Seeds; Thiazoles; Thiazolidines; Time Factors | 2006 |
Disturbance of endomembrane trafficking by brefeldin A and calyculin A reorganizes the actin cytoskeleton of Lilium longiflorum pollen tubes.
Topics: Actin Cytoskeleton; Actins; Brefeldin A; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytochalasin B; Flowers; Lilium; Marine Toxins; Models, Biological; Oxazoles; Phosphatidate Phosphatase; Phosphorylation; Protein Transport; Thiazoles; Thiazolidines | 2005 |
Coating of DNA/poly(L-lysine) complexes by covalent attachment of poly[N-(2-hydroxypropyl)methacrylamide].
Topics: Amination; DNA; Hydrolysis; Kinetics; Molecular Structure; Molecular Weight; Nitrobenzenes; Polylysine; Polymethacrylic Acids; Sodium Chloride; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 2006 |
PKC-dependent stimulation of EAAT3 glutamate transporter does not require the integrity of actin cytoskeleton.
Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cytochalasins; Depsipeptides; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamic Acid; Microtubules; Neurons; Phorbol Esters; Protein Kinase C; Protein Transport; Rats; Thiazoles; Thiazolidines | 2006 |
Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Aggregation; Cell Enlargement; Cell Polarity; Cell Shape; Chemotactic Factors; Chemotaxis; Chromones; Cyclic AMP; Dictyostelium; Enzyme Inhibitors; Green Fluorescent Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Protozoan Proteins; Signal Transduction; Thiazoles; Thiazolidines | 2006 |
Molecular dissection of internalization of Porphyromonas gingivalis by cells using fluorescent beads coated with bacterial membrane vesicle.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Androstadienes; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Binding Proteins; Caveolin 1; Cell Membrane; Chromones; Clathrin; Cytochalasin D; Dynamin II; Endocytosis; Filipin; Fluorescent Dyes; G(M1) Ganglioside; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Membrane Lipids; Membrane Microdomains; Microtubules; Morpholines; Nocodazole; Nystatin; Paclitaxel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Porphyromonas gingivalis; Recombinant Fusion Proteins; Sequence Deletion; Thiazoles; Thiazolidines; Tubulin; Wortmannin | 2005 |
Quantitative determination of latrunculins A and B in the Red Sea sponge Negombata magnifica by high performance liquid chromatography.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Calibration; Chromatography, High Pressure Liquid; Porifera; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidines | 2006 |
A reassignment of (-)-mycothiazole and the isolation of a related diol.
Topics: Alcohols; Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Drug Screening Assays, Antitumor; Epothilones; Molecular Structure; Polyketide Synthases; Porifera; Stereoisomerism; Thiazoles; Thiazolidines; Vanuatu | 2006 |
Role of the actin cytoskeleton during respiratory burst in chemoattractant-stimulated neutrophils.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Chemotactic Factors; Cytoskeleton; Depsipeptides; Enzyme Inhibitors; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Respiratory Burst; Signal Transduction; Thiazoles; Thiazolidines | 2006 |
Entamoeba histolytica: comparison of the role of receptors and filamentous actin among various endocytic processes.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cytoskeleton; Dextrans; Dose-Response Relationship, Drug; Endocytosis; Entamoeba histolytica; Erythrocytes; Fluorescein-5-isothiocyanate; Humans; Iron; Microscopy, Confocal; Microscopy, Interference; Phagocytosis; Thiazoles; Thiazolidines; Transferrin | 2006 |
Agonist-stimulated beta-adrenergic receptor internalization requires dynamic cytoskeletal actin turnover.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Adrenergic beta-Agonists; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Endocytosis; Humans; Isoproterenol; Kidney; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Thiazoles; Thiazolidines | 2006 |
Bioactive natural and semisynthetic latrunculins.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Bacillus cereus; Bridged Bicyclo Compounds, Heterocyclic; Candida albicans; Indian Ocean; Macrolides; Microbial Sensitivity Tests; Molecular Structure; Porifera; Saccharomyces cerevisiae; Staphylococcus aureus; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Wound Healing | 2006 |
Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma.
Topics: Albumins; Anilides; Animals; Cells, Cultured; Cholesterol; Chromans; Farnesol; Kidney Tubules, Proximal; Ligands; Mevalonic Acid; Opossums; Polyisoprenyl Phosphates; PPAR gamma; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Troglitazone | 2006 |
Actin cytoskeleton derangement induces apoptosis in renal ischemia/reperfusion.
Topics: Actin Cytoskeleton; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Caspases; Kidney; Male; Marine Toxins; Organ Culture Techniques; Rats; Rats, Wistar; Reperfusion Injury; Thiazoles; Thiazolidines | 2006 |
Serotonin catabolism and the formation and fate of 5-hydroxyindole thiazolidine carboxylic acid.
Topics: Animals; Brain; Indoles; Intestine, Small; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Monoamine Oxidase; PC12 Cells; Rats; Rats, Long-Evans; Serotonin; Thiazoles; Thiazolidines | 2006 |
Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytosol; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Antagonists; Gene Expression Regulation; N-Methylaspartate; Neurons; Nimodipine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Thiazoles; Thiazolidines | 2006 |
Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Lactate Dehydrogenases; Nicotine; Phosphorylation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2006 |
Hypersensitivity to cytoskeletal antagonists demonstrates microtubule-microfilament cross-talk in the control of root elongation in Arabidopsis thaliana.
Topics: Actin Cytoskeleton; Actins; Arabidopsis; Arabidopsis Proteins; Bridged Bicyclo Compounds, Heterocyclic; Cytochalasin D; Dinitrobenzenes; Microtubule-Associated Proteins; Microtubules; Mutation; Paclitaxel; Plant Roots; Sulfanilamides; Thiazoles; Thiazolidines; Tubulin Modulators | 2006 |
Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Membrane; Cytoskeleton; Fluorescent Antibody Technique; Gelsolin; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats; Rats, Wistar; RNA Interference; Thiazoles; Thiazolidines | 2006 |
Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes.
Topics: Aged; Aged, 80 and over; Animals; Aqueous Humor; Bridged Bicyclo Compounds, Heterocyclic; Cell Wall; Eye Enucleation; Humans; Intraocular Pressure; Marine Toxins; Microscopy, Electron, Scanning; Middle Aged; Perfusion; Porifera; Thiazoles; Thiazolidines; Trabecular Meshwork | 2006 |
Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Chemotaxis; Chromones; Cytochalasin D; Drosophila melanogaster; Drosophila Proteins; Egg Proteins; Embryo, Nonmammalian; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Hemocytes; In Situ Hybridization; Microscopy, Fluorescence; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Thiazoles; Thiazolidines; Time Factors | 2006 |
Effects of acrylamide, latrunculin, and nocodazole on intracellular transport and cytoskeletal organization in melanophores.
Topics: Acrylamide; Actins; alpha-MSH; Animals; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Cell Culture Techniques; Cells, Cultured; Cytoskeleton; Melanophores; Melanosomes; Microtubules; Nocodazole; Thiazoles; Thiazolidines; Xenopus laevis | 2006 |
Focal adhesions are hotspots for keratin filament precursor formation.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Line, Transformed; Epidermolysis Bullosa Simplex; Focal Adhesions; Humans; Intermediate Filaments; Keratin-14; Keratin-18; Keratins; Marine Toxins; Metalloproteins; Mice; Mutation; Paxillin; Protein Transport; Pseudopodia; RNA, Antisense; Stress Fibers; Talin; Thiazoles; Thiazolidines; Transfection; Zyxin | 2006 |
A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
Topics: Actins; Amino Acid Sequence; Amino Acid Substitution; Animals; Bridged Bicyclo Compounds, Heterocyclic; Deafness; Drug Resistance; Dystonia; Hearing Loss, Sensorineural; Humans; Male; Mice; Microsatellite Repeats; Molecular Sequence Data; Mutation, Missense; Nervous System Malformations; NIH 3T3 Cells; Phalloidine; Stress Fibers; Syndrome; Thiazoles; Thiazolidines; Transfection; Twins, Monozygotic | 2006 |
Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.
Topics: Actins; Amides; Animals; Anions; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Size; Chloride Channels; Cholesterol; Electric Conductivity; Enzyme Inhibitors; Hypotonic Solutions; Intracellular Signaling Peptides and Proteins; Ion Channels; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Polymers; Protein Serine-Threonine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; Thiazoles; Thiazolidines | 2006 |
Actin polymerisation regulates thrombin-evoked Ca(2+) signalling after activation of PAR-4 but not PAR-1 in human platelets.
Topics: Actins; Biotinylation; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Signaling; Cytochalasin D; Cytoskeleton; Fura-2; Humans; Indoles; Oligopeptides; Peptide Fragments; Protein Kinase C; Receptor, PAR-1; Receptors, Proteinase-Activated; Receptors, Thrombin; Strontium; Thiazoles; Thiazolidines; Thrombin | 2006 |
Successful computer guided planned synthesis of (4R)-thiazolidine carboxylic acid and its 2-substituted analogues as urease inhibitors.
Topics: Computer-Aided Design; Databases, Factual; Drug Design; Ligands; Models, Molecular; Thiazoles; Thiazolidines; Urease | 2006 |
Effect of H-7 and Lat-B on retinal physiology.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Dark Adaptation; Electroretinography; Enzyme Inhibitors; Fluorescein Angiography; Fluorophotometry; Injections; Macaca fascicularis; Macaca mulatta; Marine Toxins; Photic Stimulation; Retina; Retinal Vessels; Thiazoles; Thiazolidines; Vitreous Body | 2006 |
Actin polymerisation at the cytoplasmic face of eukaryotic nuclei.
Topics: Actins; Animals; Binding Sites; Biopolymers; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Circular Dichroism; Cytochalasin D; Depsipeptides; Fluorescent Dyes; HeLa Cells; Humans; Liver; Nuclear Envelope; Rabbits; Rats; Thiazoles; Thiazolidines | 2006 |
ARP2 and ARP3 are localized to sites of actin filament nucleation in tobacco BY-2 cells.
Topics: Actin Cytoskeleton; Actin-Related Protein 2; Actin-Related Protein 3; Bridged Bicyclo Compounds, Heterocyclic; Cell Nucleus; Immunoblotting; Nicotiana; Protein Transport; Thiazoles; Thiazolidines | 2006 |
Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Clathrin-Coated Vesicles; Endocytosis; Lampreys; Marine Toxins; Microscopy, Electron, Transmission; Polymers; Presynaptic Terminals; Spinal Cord; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines | 2006 |
Differential display proteomic analysis of Picea meyeri pollen germination and pollen-tube growth after inhibition of actin polymerization by latrunculin B.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Electrophoresis, Gel, Two-Dimensional; Gene Expression Profiling; Gene Expression Regulation, Plant; Germination; Mass Spectrometry; Picea; Plant Proteins; Pollen; Proteomics; Thiazoles; Thiazolidines | 2006 |
An antioxidant modulates expression of receptor activator of NF-kappaB in asthma.
Topics: Animals; Antioxidants; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Capillary Permeability; Female; Gene Expression; Glycoproteins; Immunohistochemistry; Mice; Mice, Inbred C57BL; Osteoprotegerin; Ovalbumin; Phosphorylation; Prodrugs; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidines; Vascular Endothelial Growth Factor A | 2006 |
Actin depolymerization is sufficient to induce programmed cell death in self-incompatible pollen.
Topics: Actin Cytoskeleton; Actins; Apoptosis; Biopolymers; Bridged Bicyclo Compounds, Heterocyclic; Caspase 3; Caspases; Depsipeptides; Papaver; Pollen; Thiazoles; Thiazolidines | 2006 |
Intestinal-specific PPARgamma deficiency enhances tumorigenesis in ApcMin/+ mice.
Topics: Animals; Colonic Neoplasms; Disease Progression; Female; Genes, APC; Genotype; Immunohistochemistry; Intestinal Neoplasms; Male; Mice; Mice, Knockout; Phenotype; PPAR gamma; Sex Factors; Thiazoles; Thiazolidines | 2006 |
To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.
Topics: Bridged Bicyclo Compounds, Heterocyclic; cdc42 GTP-Binding Protein; Cell Differentiation; Cell Polarity; Cells, Cultured; Chemotaxis, Leukocyte; HL-60 Cells; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenotype; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Transport; Pseudopodia; rhoA GTP-Binding Protein; Signal Transduction; Thiazoles; Thiazolidines | 2006 |
Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling.
Topics: Actin Cytoskeleton; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dinitrobenzenes; Escherichia coli; Green Fluorescent Proteins; Microfilament Proteins; Molecular Sequence Data; Nicotiana; Plant Leaves; Plant Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sulfanilamides; Thiazoles; Thiazolidines; Tubulin Modulators | 2006 |
Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides.
Topics: Aldehydes; Calpain; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Activation; HeLa Cells; Humans; Molecular Structure; Proline; Pyrrolidinones; Stereoisomerism; Structure-Activity Relationship; Sulfones; Thiazoles; Thiazolidines | 2006 |
Influence of soil physicochemical and biological properties on the degradation and adsorption of the nematicide fosthiazate.
Topics: Adsorption; Anti-Bacterial Agents; Antinematodal Agents; Fungicides, Industrial; Half-Life; Hydrogen-Ion Concentration; Organophosphorus Compounds; Soil; Soil Microbiology; Thiazoles; Thiazolidines | 2006 |
Effects of glutathione supplementation during peritoneal dialysis.
Topics: Animals; Cells, Cultured; Collagen; Epithelium; Erythrocytes; Glutathione Peroxidase; Hemodialysis Solutions; Male; Peritoneal Dialysis; Peritoneum; Proteins; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Tissue Adhesions | 2006 |
Structure-activity relationships from in vitro efficacies of the thiazolide series against the intracellular apicomplexan protozoan Neospora caninum.
Topics: Animals; Antiprotozoal Agents; Cattle; Dogs; Drug Design; Neospora; Nitro Compounds; Polymerase Chain Reaction; Structure-Activity Relationship; Thiazoles; Thiazolidines; Tissue Culture Techniques | 2007 |
Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model.
Topics: Animals; Colitis; Colon; Cysteine; Dextran Sulfate; Drug Delivery Systems; Glutathione; Interleukin-12; Interleukin-6; Male; Mice; Mice, Inbred ICR; Sucrose; Thiazoles; Thiazolidines; Up-Regulation | 2007 |
Design and synthesis of thiazoline-thiazole hybrid macrocycles possessing strong binding affinity to Pb2+ and Cd2+.
Topics: Cadmium; Cations, Divalent; Drug Design; Heterocyclic Compounds; Hydrogen Bonding; Lead; Macromolecular Substances; Metals, Heavy; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2007 |
Synthesis of new pyrazolothiazole derivatives from 4-thiazolidinones.
Topics: Pyrazoles; Thiazoles; Thiazolidines | 2007 |
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth.
Topics: Enzyme Inhibitors; Intramolecular Transferases; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2008 |
Interaction studies and alanine scanning analysis of a semi-synthetic split intein reveal thiazoline ring formation from an intermediate of the protein splicing reaction.
Topics: Alanine; Alternative Splicing; Amino Acid Sequence; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Inteins; Kinetics; Molecular Sequence Data; Peptides; Plasmids; Protein Structure, Tertiary; Proteins; Spectrometry, Fluorescence; Thiazoles; Thiazolidines | 2008 |
Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression.
Topics: Adjuvants, Immunologic; Animals; Body Weight; C-Reactive Protein; Cell Proliferation; Cell Survival; Cyclophosphamide; Drug Synergism; Immunosuppressive Agents; Killer Cells, Natural; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Organ Size; Panax; Polysaccharides; Pyrrolidonecarboxylic Acid; Spleen; Tetrazolium Salts; Thiazoles; Thiazolidines | 2008 |
Design, microwave-assisted synthesis and HIV-RT inhibitory activity of 2-(2,6-dihalophenyl)-3-(4,6-dimethyl-5-(un)substituted-pyrimidin-2-yl)thiazolidin-4-ones.
Topics: Anti-HIV Agents; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microwaves; Molecular Structure; Pyrimidines; Thiazoles; Thiazolidines | 2009 |
Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: an analogue-based drug design approach.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Benzyl Compounds; Carrageenan; Dose-Response Relationship, Drug; Drug Design; Edema; Female; Hindlimb; Male; Oxazoles; Plethysmography; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2009 |
Bicyclic cyanothiazolidines as novel dipeptidyl peptidase 4 inhibitors.
Topics: Azabicyclo Compounds; Catalysis; Diabetes Mellitus; Dipeptidyl-Peptidase IV Inhibitors; Drug Design; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Nitriles; Protein Structure, Tertiary; Pyrrolidines; Structure-Activity Relationship; Thiazoles; Thiazolidines; Time Factors | 2009 |
A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cysteine; Drug Delivery Systems; Enzyme Inhibitors; Glycine; HeLa Cells; Humans; Molecular Sequence Data; Monoacylglycerol Lipases; Mutagenesis, Site-Directed; Rats; Structure-Activity Relationship; Substrate Specificity; Thiazoles; Thiazolidines | 2009 |
Synthesis, spectral and biological evaluation of some new thiazolidinones and thiazoles based on t-3-alkyl-r-2,c-6-diarylpiperidin-4-ones.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Fungi; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2009 |
Cytotoxicity and utility of 1-indanone in the synthesis of some new heterocycles.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Survival; Heterocyclic Compounds; Humans; Hydrazones; Indans; Neoplasms; Thiazoles; Thiazolidines; Triazines | 2010 |
2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.
Topics: Administration, Oral; Animals; Cell Line; Cricetinae; Cricetulus; Dogs; Hepatocytes; High-Throughput Screening Assays; Humans; Imines; Lymphocyte Count; Male; Microsomes, Liver; Radioligand Assay; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2010 |
Concise total synthesis of largazole.
Topics: Catalysis; Depsipeptides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Thiazoles; Thiazolidines | 2010 |
Screening multicomponent reactions for X-linked inhibitor of apoptosis-baculoviral inhibitor of apoptosis protein repeats domain binder.
Topics: Amino Acid Motifs; Amino Acid Sequence; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Databases, Factual; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Peptidomimetics; Piperazines; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Thiazoles; Thiazolidines; X-Linked Inhibitor of Apoptosis Protein | 2011 |
HL005--a new selective PPARγ antagonist specifically inhibits the proliferation of MCF-7.
Topics: Aminobenzoates; Benzoic Acid; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Humans; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; PPAR gamma; Protein Binding; Thiazoles; Thiazolidines; Two-Hybrid System Techniques | 2011 |
Benzisothiazolyliminothiazolidin-4-ones with chondroprotective properties: searching for potent and selective inhibitors of MMP-13.
Topics: Binding Sites; Computer Simulation; Humans; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Models, Molecular; Protease Inhibitors; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2011 |
Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.
Topics: Drug Design; Enzyme Activation; Enzyme Inhibitors; Humans; Monoacylglycerol Lipases; Recombinant Proteins; Thiazoles; Thiazolidines | 2011 |
Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cyanobacteria; Depsipeptides; Drug Design; Humans; Inhibitory Concentration 50; Isoleucine; Magnetic Resonance Spectroscopy; Models, Chemical; Neoplasms; Proto-Oncogene Proteins c-mdm2; Ribosomes; Thiazoles; Thiazolidines; Tumor Suppressor Protein p53 | 2012 |
Direct preparation of thiazoles, imidazoles, imidazopyridines and thiazolidines from alkenes.
Topics: Alkenes; Cyclization; Imidazoles; Pyridines; Thiazoles; Thiazolidines | 2012 |
BAI, a novel cyclin-dependent kinase inhibitor induces apoptosis in A549 cells through activation of caspases and inactivation of Akt.
Topics: Acetamides; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; Humans; Indazoles; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Thiazoles; Thiazolidines | 2013 |
Synthesis and QSAR modeling of novel benzimidazolo thiazolidinones, thiazinones and 5-arylidene-2-imino thiazolidinones as antibacterial agents.
Topics: Anti-Bacterial Agents; Bacteria; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Models, Molecular; Quantitative Structure-Activity Relationship; Thiazoles; Thiazolidines | 2013 |
Synthesis and pharmacological evaluation of a novel series of 3-aryl-2-(2-substituted-4-methylthiazole-5-yl)thiazolidin-4-one as possible anti-inflammatory and antimicrobial agents.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Bacterial Infections; Carrageenan; Edema; Fungi; Humans; Indomethacin; Microbial Sensitivity Tests; Mycoses; Rats; Thiazoles; Thiazolidines | 2012 |
Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels.
Topics: Animals; Benzothiazoles; Blood-Brain Barrier; Capillary Permeability; Cells, Cultured; Drug Evaluation, Preclinical; Female; HSP70 Heat-Shock Proteins; Humans; MCF-7 Cells; Mice; Microsomes, Liver; Pyridines; tau Proteins; Thiazoles; Thiazolidines | 2013 |
Heterocyclic tautomerism: reassignment of two crystal structures of 2-amino-1,3-thiazolidin-4-one derivatives.
Topics: Aminobenzoates; Crystallography, X-Ray; Hydrogen Bonding; Molecular Structure; Pyridines; Thiazoles; Thiazolidines | 2014 |
A short stereoselective synthesis of prepiscibactin using a SmI2-mediated Reformatsky reaction and Zn2+-induced asymmetric thiazolidine formation.
Topics: Animals; Cysteine; Fish Diseases; Fishes; Iodides; Molecular Structure; Nitriles; Pasteurella Infections; Pfiesteria piscicida; Photobacterium; Samarium; Stereoisomerism; Thiazoles; Thiazolidines; Zinc | 2014 |
Characterization of potent fusion inhibitors of influenza virus.
Topics: Animals; Dogs; Electrophoresis, Polyacrylamide Gel; Fluorescence; HeLa Cells; Humans; Hydrogen-Ion Concentration; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Microscopy, Electron; Norbornanes; Tetrazolium Salts; Thiazoles; Thiazolidines; Trypsin; Viral Fusion Protein Inhibitors; Viral Plaque Assay; Virion; Virus Internalization | 2015 |
KCC2 function modulates in vitro ictogenesis.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bumetanide; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; K Cl- Cotransporters; Male; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Symporters; Thiazoles; Thiazolidines; Thioglycolates; Tissue Culture Techniques | 2015 |
Effect of alkyl group on transnitrosation of N-nitrosothiazolidine thiocarboxamides.
Topics: Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Nitrosation; Nitroso Compounds; Quantum Theory; Thiazoles; Thiazolidines | 2015 |
Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Brain Neoplasms; Cell Line, Tumor; Class I Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Glioma; Humans; Imidazoles; Molecular Targeted Therapy; Neoplastic Stem Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Pyridazines; Signal Transduction; Thiazoles; Thiazolidines | 2016 |
Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Humans; Inhibitory Concentration 50; Isoquinolines; MCF-7 Cells; Models, Molecular; Molecular Structure; Pyridines; Quinolines; Structure-Activity Relationship; Thiazoles; Thiazolidines; Thiophenes | 2016 |
Discovery and structure-activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors.
Topics: Anti-Bacterial Agents; Cell Survival; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Mutation; Structure-Activity Relationship; Thiazoles; Thiazolidines; Topoisomerase II Inhibitors | 2016 |
Synthesis and Evaluation of Thiazolidine Amide and N-Thiazolyl Amide Fluoroquinolone Derivatives.
Topics: Amides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Fluoroquinolones; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2017 |
Synthesis and biological evaluation of 2-aminothiazole-thiazolidinone conjugates as potential antitubercular agents.
Topics: Antitubercular Agents; Cell Line; Drug Design; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Thiazoles; Thiazolidines; Tuberculosis | 2018 |
Ovicidal in vitro activity of 2-aryl-3-(2-morpholinoethyl)thiazolidin-4-ones and 2-aryl-3-(3-morpholinopropyl)thiazolidin-4-ones against Fasciola hepatica (Linnaeus, 1758).
Topics: Animals; Anthelmintics; Brazil; Cattle; Cell Line; Fasciola hepatica; Inhibitory Concentration 50; Kidney; Liver; Ovum; Parasite Egg Count; Tetrazolium Salts; Thiazoles; Thiazolidines | 2018 |
Building upon Nature's Framework: Overview of Key Strategies Toward Increasing Drug-Like Properties of Natural Product Cyclopeptides and Macrocycles.
Topics: Anthraquinones; Biological Availability; Biological Products; Chemistry, Pharmaceutical; Cyclosporine; Cyclotides; Daptomycin; Depsipeptides; Drug Design; Drug Discovery; Ethers, Cyclic; Gramicidin; Lipopeptides; Macrocyclic Compounds; Macrolides; omega-Conotoxins; Organophosphorus Compounds; Oxazoles; Peptides; Peptides, Cyclic; Thiazoles; Thiazolidines | 2019 |
Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis.
Topics: Acrylamides; Actins; Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Biopsy; Bridged Bicyclo Compounds, Heterocyclic; C9orf72 Protein; Cell Line; Cerebral Cortex; Embryo, Mammalian; Fibroblasts; Humans; Microscopy, Electron, Transmission; Motor Neurons; Mutation; Nuclear Pore; Primary Cell Culture; Profilins; Protein Multimerization; Skin; Thiazoles; Thiazolidines | 2019 |
Novel Thiazole-Based Thiazolidinones as Potent Anti-infective Agents:
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus fumigatus; Aspergillus niger; Drug Design; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Penicillium; Software; Talaromyces; Thiazoles; Thiazolidines | 2020 |
The first Q-Tube based high-pressure synthesis of anti-cancer active thiazolo[4,5-c]pyridazines via the [4 + 2] cyclocondensation of 3-oxo-2-arylhydrazonopropanals with 4-thiazolidinones.
Topics: Antineoplastic Agents; Cell Proliferation; Chemistry Techniques, Synthetic; Chemistry, Pharmaceutical; Cyclization; Doxorubicin; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Pressure; Pyridazines; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2020 |
2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies.
Topics: Anti-Infective Agents; Bacterial Proteins; Binding Sites; Carbohydrate Dehydrogenases; Gram-Negative Bacteria; Gram-Positive Bacteria; Isomerism; Microbial Sensitivity Tests; Molecular Docking Simulation; Thiazoles; Thiazolidines | 2021 |
Antimicrobial and synergistic activity of thiazoline derivatives in combination with conventional antibiotics against multidrug resistant Staphylococcus aureus isolated from abscess drainage samples.
Topics: Abscess; Anti-Bacterial Agents; Disk Diffusion Antimicrobial Tests; Drainage; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Ribotyping; Staphylococcal Infections; Staphylococcus aureus; Thiazoles; Thiazolidines | 2020 |
Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies.
Topics: Anti-Inflammatory Agents; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Lipoxygenase Inhibitors; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Thiazoles; Thiazolidines | 2023 |