thiazoles has been researched along with tg 003 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Furuichi, K; Hagiwara, M; Hosoya, T; Kimura, H; Koizumi, J; Koizumi, T; Krainer, AR; Muraki, M; Murray, MV; Ohkawara, B; Onogi, H; Shibuya, H; Sumi, K; Suzuki, M; Yomoda, J | 1 |
| Hagiwara, M; Hosoya, T; Kataoka, N; Kimura, H; Muraki, M; Suzuki, M; Yomoda, J | 1 |
| James, BP; Meuillet, E; Powis, G; Staatz, WD; Wilkinson, ST | 1 |
| Auld, DS; Bougie, JM; Maloney, DJ; Misteli, T; Mott, BT; Nguyen, DT; Rosenthal, AS; Shen, M; Tanega, C; Thomas, CJ | 1 |
| Awano, H; Hagiwara, M; Itoh, K; Kataoka, N; Matsuo, M; Nishida, A; Ota, M; Takeshima, Y; Yagi, M | 1 |
| Hagiwara, M; Kataoka, N; Ninomiya, K | 1 |
| Carter, G; Cooper, DR; Gower, KM; Li, P; Patel, NA; Romero, J; Watson, J | 1 |
| Asada, T; Hagiwara, M; Kawamoto, D; Kii, I; Kurihara, T; Miyata, A; Sakurai, E; Tanabe, T; Toyomoto, M; Yoshimura, M | 1 |
| Hagiwara, M; Iida, K; Sakuma, M | 1 |
| Hagiwara, M; Hashimoto, N; Hosoya, T; Kii, I; Koike, Y; Matsuo, M; Ninomiya, K; Nishida, A; Ohe, K; Okuno, Y; Sako, Y; Toyomoto, M; Yoshida, S | 1 |
| Bowler, E; Ladomery, M; Porazinski, S; Uzor, S; Wilson, I; Zorzou, P | 1 |
| Ajiro, M; Alqasem, AA; Clark, B; Hagiwara, M; Iida, K; Ladomery, MR; Li, L; Oltean, S; Perks, CM; Porazinski, SR; Uzor, S; Wilson, ID | 1 |
12 other study(ies) available for thiazoles and tg 003
| Article | Year |
|---|---|
Manipulation of alternative splicing by a newly developed inhibitor of Clks.
Topics: Alternative Splicing; Animals; Arginine; Binding Sites; Cell Nucleus; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Globins; HeLa Cells; Humans; Microscopy, Fluorescence; Models, Chemical; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; Serine; Signal Transduction; Thiazoles; Time Factors; Xenopus; Xenopus laevis | 2004 |
Combination of Clk family kinase and SRp75 modulates alternative splicing of Adenovirus E1A.
Topics: Adenoviridae; Adenovirus E1A Proteins; Alternative Splicing; Animals; Cells, Cultured; HeLa Cells; Humans; Mice; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA-Binding Proteins; RNA, Messenger; Serine-Arginine Splicing Factors; Thiazoles | 2008 |
Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells.
Topics: Aging, Premature; Animals; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Gene Expression Regulation; HeLa Cells; Humans; Mutation; Oxidative Stress; Paraquat; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA, Small Interfering; Superoxide Dismutase; Superoxide Dismutase-1; Survival Analysis; Thiazoles | 2009 |
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
Topics: Dyrk Kinases; Enzyme Activation; Enzyme Inhibitors; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Molecular Structure; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinazolines; Small Molecule Libraries; Substrate Specificity; Thiazoles | 2011 |
Chemical treatment enhances skipping of a mutated exon in the dystrophin gene.
Topics: Animals; Cell Line; Child, Preschool; Chlorocebus aethiops; Codon, Nonsense; Dystrophin; Exons; Humans; Male; Muscular Dystrophy, Duchenne; Phenotype; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA Splicing; RNA, Messenger; Sequence Deletion; Thiazoles | 2011 |
Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor.
Topics: Animals; Heat-Shock Response; Humans; Mice; NIH 3T3 Cells; Osmotic Pressure; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA Precursors; RNA Splicing; RNA-Binding Proteins; RNA, Messenger; Thiazoles | 2011 |
Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Alternative Splicing; Animals; Binding Sites; Gene Expression Regulation, Neoplastic; Mice; Mutation; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Serine-Arginine Splicing Factors; Thiazoles | 2013 |
Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.
Topics: Animals; Carrageenan; Casein Kinase I; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Humans; Hyperalgesia; Indoles; Inflammation; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Pain Threshold; Phloroglucinol; Protein Transport; Spinal Cord; Thiazoles | 2014 |
Deciphering targeting rules of splicing modulator compounds: case of TG003.
Topics: Alternative Splicing; Animals; Base Sequence; Binding Sites; Cell Line; Exons; Gene Expression Profiling; HEK293 Cells; Humans; Mice; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myoblasts, Skeletal; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrimidines; RNA Splice Sites; RNA Splicing; Sequence Analysis, RNA; Thiazoles | 2015 |
Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy.
Topics: Administration, Oral; Animals; Dystrophin; Enzyme Inhibitors; Exons; Genes, Reporter; HeLa Cells; Humans; Male; Mice; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; RNA Splicing; Thiazoles | 2017 |
Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention.
Topics: Alternative Splicing; Cell Line, Tumor; Exons; Gene Expression Regulation; Harmine; HL-60 Cells; Homeostasis; Hot Temperature; Humans; Introns; Neoplasms; Osmotic Pressure; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Stress, Physiological; Thiazoles | 2018 |
CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.
Topics: Alternative Splicing; Animals; Apoptosis; Benzothiazoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin-Dependent Kinases; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice, Nude; Molecular Targeted Therapy; Neoplasm Invasiveness; Prostatic Neoplasms; Protein Kinase Inhibitors; RNA-Seq; Thiazoles; Xenograft Model Antitumor Assays | 2021 |