thiazoles has been researched along with tetomilast in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Blocher, CR; Bloomfield, GL; Fisher, BJ; Fowler, AA; Nagamoto, H; Ridings, PC; Sugerman, HJ | 1 |
| Barnard, JW; Shappell, K; Yoshitake, M | 1 |
| Bkaily, G; D'orléans-Juste, P | 1 |
| Cheng, XS; Egashira, K; Fukuyama, N; Momii, H; Nakazawa, H; Oyama, J; Shimokawa, H; Takeshita, A | 1 |
| Eguchi, Y; Ejiri, S; Kishida, A; Kodama, M; Kurumi, Y; Tani, T | 1 |
| Banan, A; Fitzpatrick, L; Keshavarzian, A; Zhang, Y | 1 |
| Aki, S; Fujioka, T; Ishigami, M; Minamikawa, J | 1 |
| Hasegawa, T; Kambayashi, Y; Kuwano, H; Nagamoto, H; Nakano, M; Sakurai, K; Saniabadi, AR; Takahashi, A; Tsukada, K | 1 |
| Gotham, S | 1 |
| Cohen, RD; Ross, AS | 1 |
| O'Mahony, S | 1 |
| Guzman, JP; Hanauer, SB; Isaacs, KL; Keshavarzian, A; Orlandi, C; Schollenberger, J; Schreiber, S | 1 |
| Chinen, H; Hibi, T; Hisamatsu, T; Ichikawa, H; Kamada, N; Kitazume, MT; Kobayashi, T; Nagamoto, H; Okamoto, S | 1 |
| Baila, B; Endo, J; Fujiwara, H; Fujiwara, T; Funaguchi, N; Ito, F; Kotosai, K; Minatoguchi, S; Mori, H; Nagamoto, H; Ohno, Y; Takemura, G; Yabuuchi, Y | 1 |
| Bickston, SJ; Kappus, MR; Snider, KR | 1 |
| Song, SD; Tang, HF | 1 |
| Marafini, I; Monteleone, G; Salvatori, S; Troncone, E | 1 |
| Fortescue, R; Janjua, S; Poole, P | 1 |
5 review(s) available for thiazoles and tetomilast
| Article | Year |
|---|---|
Medical therapy for ulcerative colitis: the state of the art and beyond.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Butyrates; Colitis, Ulcerative; Cyclosporine; Epidermal Growth Factor; Glucocorticoids; Humans; Immunosuppressive Agents; Infliximab; Interferons; Mercaptopurine; Plasmapheresis; Probiotics; Remission Induction; Thiazoles | 2004 |
Tetomilast: new promise for phosphodiesterase-4 inhibitors?
Topics: Animals; Anti-Inflammatory Agents; Humans; Inflammatory Bowel Diseases; Phosphodiesterase 4 Inhibitors; Thiazoles | 2012 |
[Progress in PDE4 targeted therapy for inflammatory diseases].
Topics: Aminopyridines; Aminoquinolines; Arthritis; Asthma; Benzamides; Cyclopropanes; Dermatitis; Humans; Inflammation; Inflammatory Bowel Diseases; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Sulfones; Thalidomide; Thiazoles | 2014 |
TGF-β activity restoration and phosphodiesterase 4 inhibition as therapeutic options for inflammatory bowel diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Oligonucleotides; Phosphodiesterase 4 Inhibitors; Thalidomide; Thiazoles; Transforming Growth Factor beta | 2020 |
Phosphodiesterase-4 inhibitors for chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aminopyridines; Benzamides; Cyclohexanecarboxylic Acids; Cyclopropanes; Diarrhea; Disease Progression; Forced Expiratory Volume; Humans; Middle Aged; Nitriles; Peak Expiratory Flow Rate; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Quality of Life; Randomized Controlled Trials as Topic; Thiazoles; Vital Capacity | 2020 |
1 trial(s) available for thiazoles and tetomilast
| Article | Year |
|---|---|
A randomized, placebo-controlled, phase II study of tetomilast in active ulcerative colitis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Colitis, Ulcerative; Cyclic Nucleotide Phosphodiesterases, Type 4; Female; Humans; Male; Middle Aged; Phosphodiesterase Inhibitors; Placebos; Remission Induction; Sigmoidoscopy; Thiazoles; Treatment Outcome | 2007 |
12 other study(ies) available for thiazoles and tetomilast
| Article | Year |
|---|---|
OPC-6535, a superoxide anion production inhibitor, attenuates acute lung injury.
Topics: Administration, Inhalation; Animals; Anions; Bronchoalveolar Lavage Fluid; Cell Cycle; Disease Models, Animal; Endothelium; Hemodynamics; Integrins; Leukocyte Count; Lung Diseases; Neutrophil Activation; Neutrophils; Oxygen; Peroxidase; Pulmonary Circulation; Respiratory Burst; Sepsis; Superoxides; Swine; Thiazoles | 1997 |
Reversal of ischemia/reperfusion lung injury by inhibition of polymorphonuclear leukocytes.
Topics: Animals; Antioxidants; Lung; Neutrophils; Rats; Reperfusion Injury; Thiazoles | 1999 |
Cytokine-induced free radicals and their roles in myocardial dysfunctions.
Topics: Animals; Antioxidants; Cardiomyopathies; Cytokines; Free Radicals; Humans; Myocardial Contraction; Myocardium; Nitric Oxide; Reactive Oxygen Species; Thiazoles | 1999 |
Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo.
Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Dogs; Echocardiography; Female; Interleukin-1; Male; Myocardium; Nitrates; Random Allocation; Stroke Volume; Superoxides; Thiazoles; Tyrosine; Ventricular Dysfunction, Left | 1999 |
Protective effect of OPC-6535, a superoxide anion production inhibitor, on liver grafts subjected to warm ischemia during porcine liver transplantation.
Topics: Animals; Antioxidants; Bilirubin; Epoprostenol; Graft Survival; Hepatectomy; Hypertonic Solutions; Ischemia; Liver Transplantation; Organ Preservation; Organ Preservation Solutions; Platelet Aggregation Inhibitors; Reperfusion Injury; Superoxides; Swine; Thiazoles; Time Factors; Tissue and Organ Harvesting | 2000 |
OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability.
Topics: Actins; Alanine; Antioxidants; Blotting, Western; Caco-2 Cells; Cytoskeleton; Fluorescent Dyes; Humans; Immunoblotting; Intestinal Mucosa; Microscopy, Fluorescence; Oxidants; Oxidation-Reduction; Permeability; Quinolones; Reactive Oxygen Species; Thiazoles | 2001 |
A practical synthesis of 3,4-diethoxybenzthioamide based on Friedel-Crafts reaction with potassium thiocyanate in methanesulfonic acid.
Topics: Indicators and Reagents; Mesylates; Superoxides; Thiazoles; Thioamides; Thiocyanates | 2002 |
Effects of OPC-6535 on lipopolysaccharide-induced acute liver injury in the rat: involvement of superoxide and tumor necrosis factor-alpha from hepatic macrophages.
Topics: Animals; Chemokine CXCL1; Chemokines, CXC; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Liver; Luminescent Measurements; Macrophages; Male; Nitroblue Tetrazolium; Perfusion; Peroxidase; Pyrazines; Rats; Rats, Wistar; Superoxides; Thiazoles; Tumor Necrosis Factor-alpha | 2003 |
Digestive Disease Week 2004. Bowel inflammation.
Topics: Azepines; Cholinergic Agents; Colitis, Ulcerative; Crohn Disease; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Isoquinolines; Pyridazines; Tacrolimus; Thiazoles | 2004 |
Tetomilast.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colitis, Ulcerative; Contraindications; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Structure-Activity Relationship; Thiazoles | 2005 |
Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice.
Topics: Administration, Oral; Analysis of Variance; Animals; CD4-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Chronic Disease; Colitis; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-10; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Probability; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Thiazoles | 2008 |
Tetomilast attenuates elastase-induced pulmonary emphysema through inhibition of oxidative stress in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Male; Oxidative Stress; Pancreatic Elastase; Pneumonia; Pulmonary Emphysema; Rabbits; Thiazoles | 2012 |