Page last updated: 2024-08-21

thiazoles and taxane

thiazoles has been researched along with taxane in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bollbuck, B; Downing, KH; Fojo, T; Giannakakou, P; Gussio, R; Nicolaou, KC; Nogales, E; Poy, G; Sackett, D; Zaharevitz, D	1
Cristofanilli, M; Gradishar, WJ; Helenowski, I; Jain, S; Rademaker, A; Santa-Maria, CA; Shah, AN; Siziopikou, K	1
Bai, Y; Gang, X; Huang, H; Karnes, RJ; Lv, Q; Ma, L; Pan, Y; Wu, Q; Yan, Y; Yang, Y; Zhang, J	1

Trials

1 trial(s) available for thiazoles and taxane

Article	Year
Phase I study of alpelisib (BYL-719) and trastuzumab emtansine (T-DM1) in HER2-positive metastatic breast cancer (MBC) after trastuzumab and taxane therapy. Breast cancer research and treatment, 2018, Volume: 171, Issue:2 Topics: Ado-Trastuzumab Emtansine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Bridged-Ring Compounds; Female; Humans; Kaplan-Meier Estimate; Maximum Tolerated Dose; Maytansine; Middle Aged; Neoplasm Staging; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Retreatment; Taxoids; Thiazoles; Trastuzumab; Treatment Outcome	2018

Article

Year

Phase I study of alpelisib (BYL-719) and trastuzumab emtansine (T-DM1) in HER2-positive metastatic breast cancer (MBC) after trastuzumab and taxane therapy.

Breast cancer research and treatment, 2018, Volume: 171, Issue:2

Topics: Ado-Trastuzumab Emtansine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Bridged-Ring Compounds; Female; Humans; Kaplan-Meier Estimate; Maximum Tolerated Dose; Maytansine; Middle Aged; Neoplasm Staging; Phosphatidylinositol 3-Kinases; Receptor, ErbB-2; Retreatment; Taxoids; Thiazoles; Trastuzumab; Treatment Outcome

2018

Other Studies

2 other study(ies) available for thiazoles and taxane

Article	Year
A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6 Topics: Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Diterpenes; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Mutation; Paclitaxel; Protein Conformation; Structure-Activity Relationship; Taxoids; Thiazoles; Tubulin; Tumor Cells, Cultured	2000
Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer. Theranostics, 2019, Volume: 9, Issue:17 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Forkhead Box Protein O1; Humans; Male; Mice; Mice, Nude; Mice, SCID; Mutation; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; PTEN Phosphohydrolase; Taxoids; Tetrazolium Salts; Thiazoles	2019

Article

Year

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells.

Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6

Topics: Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Diterpenes; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Mutation; Paclitaxel; Protein Conformation; Structure-Activity Relationship; Taxoids; Thiazoles; Tubulin; Tumor Cells, Cultured

2000

Overcoming EZH2 Inhibitor Resistance by Taxane in PTEN-Mutated Cancer.

Theranostics, 2019, Volume: 9, Issue:17

Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cell Line, Tumor; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Forkhead Box Protein O1; Humans; Male; Mice; Mice, Nude; Mice, SCID; Mutation; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; PTEN Phosphohydrolase; Taxoids; Tetrazolium Salts; Thiazoles

2019