thiazoles has been researched along with tak-715 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arikawa, Y; Asahi, S; Kimura, H; Kotani, E; Miwatashi, S; Miyamoto, M; Naruo, K; Ohkawa, S; Tanaka, T | 1 |
| Azevedo, R; de Vlieg, J; Kazemier, B; Oubrie, A; Raaijmakers, H; van Zeeland, M | 1 |
| Falck, D; Giera, M; Honing, M; Kool, J; Niessen, WM; Rahimi Pirkolachachi, F | 1 |
3 other study(ies) available for thiazoles and tak-715
| Article | Year |
|---|---|
Novel inhibitor of p38 MAP kinase as an anti-TNF-alpha drug: discovery of N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]-2-pyridyl]benzamide (TAK-715) as a potent and orally active anti-rheumatoid arthritis agent.
Topics: Administration, Oral; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Biological Availability; Cell Line; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Male; Mice; Microsomes; Models, Molecular; Monocytes; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred Lew; Structure-Activity Relationship; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
X-ray structure of p38α bound to TAK-715: comparison with three classic inhibitors.
Topics: Adenosine Triphosphate; Benzamides; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Humans; Imidazoles; Indoles; Ligands; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Pyridazines; Pyridines; Pyrimidines; Structure-Activity Relationship; Thiazoles | 2012 |
Comparison of (bio-)transformation methods for the generation of metabolite-like compound libraries of p38α MAP kinase inhibitors using high-resolution screening.
Topics: Bacillus megaterium; Benzamides; Chemistry, Pharmaceutical; Cytochrome P-450 Enzyme System; High-Throughput Screening Assays; Humans; Hydrogen Peroxide; Imidazoles; Indoles; Light; Liver; Microsomes, Liver; Mitogen-Activated Protein Kinase 14; Naphthalenes; Oxygen; Photochemistry; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2014 |