Page last updated: 2024-08-21

thiazoles and t16ainh-a01

thiazoles has been researched along with t16ainh-a01 in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's18 (81.82)24.3611
2020's4 (18.18)2.80

Authors

AuthorsStudies
Albert, AP; Chadha, PS; Davis, AJ; Greenwood, IA; Leblanc, N; Pritchard, HA; Shi, J; Vasilikostas, G; Verkman, AS; Yao, Z1
Eisenman, ST; Farrugia, G; Gibbons, SJ; Mazzone, A; Ordog, T; Strege, PR; Yao, Z1
Ayon, RJ; Davis, AJ; Duan, DD; Forrest, AS; Freitas, N; Greenwood, IA; Huebner, ML; Joyce, J; Joyce, TC; Leblanc, N; Singer, CA; Valencik, ML; Wiwchar, M; Ye, L1
Bradley, E; Fedigan, S; Hollywood, MA; McHale, NG; Sergeant, GP; Thornbury, KD; Webb, T1
Akcakaya, P; Berglund, D; Berglund, E; Bogdanović, D; Bränström, R; Fröbom, R; Karlsson, F; Larsson, C; Lee, L; Lui, WO; Vukojević, V; Zedenius, J1
Birnbaumer, L; Singh, BB; Sun, Y1
Andersson, KE; Boedtkjer, DM; Jensen, AB; Kim, S; Matchkov, VM1
Bessac, BF; Deba, F1
Cai, Z; Duan, W; Li, H; Li, R; Li, X; Niu, Z; Yan, X; Zhang, A; Zhang, H1
Koh, SD; Leblanc, N; O'Driscoll, K; Sanders, KM; Sung, TS; Yapp, NJ; Zheng, H1
Gao, J; Guan, L; Song, Y; Wang, K1
Cordero-Martínez, J; Garduño-Siciliano, L; Hernández-González, EO; Maldonado-García, D; Reyes-Miguel, T; Roa-Espitia, AL; Rodríguez-Páez, L1
García, G; Martínez-Rojas, VA; Murbartián, J; Oviedo, N1
Guo, ZK; Ma, KT; Si, JQ; Tian, XQ; Wang, XW; Wang, Y1
Qi, Q; Wu, K; Xie, Q; Yang, Y1
Choi, S; Hong, C; Jiao, HY; Jun, JY; Kang, HG; Shin, DH; Wu, MJ1
Li, L; Liu, YH; Ma, KT; Si, JQ; Song, J; Tan, CY; Wang, Y; Wang, YP; Zhang, AM; Zhang, ZP; Zhou, Y1
Berglund, E; Bränström, R; Fröbom, R; Larsson, C; Lui, WO; Nilsson, IL; Sellberg, F; Xu, C; Zhao, A1
Asai, K; Imaizumi, Y; Suzuki, T; Suzuki, Y; Yamamura, H; Yasumoto, M1
Chang, YC; Chen, L; Feng, ZY; Li, L; Li, XR; Ma, KT; Si, JQ; Zhou, Y1
Cao, N; Chen, Q; Deng, S; Gao, R; Kong, L; Li, L; Ma, K; Si, J; Tan, C; Tang, X; Wang, Y; Xu, Z; Zhang, J; Zhang, L; Zhang, M1
Amano, T; Fujii, N; Honda, Y; Kenny, GP; Kondo, N; Lei, TH; Mündel, T; Nishiyasu, T1

Other Studies

22 other study(ies) available for thiazoles and t16ainh-a01

ArticleYear
Potent vasorelaxant activity of the TMEM16A inhibitor T16A(inh) -A01.
    British journal of pharmacology, 2013, Volume: 168, Issue:3

    Topics: Adipose Tissue; Animals; Anoctamin-1; Aorta, Thoracic; Chloride Channels; Humans; Mesenteric Arteries; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Neoplasm Proteins; Pulmonary Artery; Pyrimidines; Rabbits; Thiazoles; Vasodilator Agents

2013
Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.
    Biochemical and biophysical research communications, 2012, Oct-19, Volume: 427, Issue:2

    Topics: Animals; Anoctamin-1; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chloride Channels; HEK293 Cells; Humans; Intestine, Small; Mice; Mice, Inbred BALB C; Muscle, Smooth; Neoplasm Proteins; Pyrimidines; Thiazoles

2012
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension.
    American journal of physiology. Cell physiology, 2012, Dec-15, Volume: 303, Issue:12

    Topics: Animals; Anoctamin-1; Calcium Channel Blockers; Chloride Channel Agonists; Chloride Channels; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indomethacin; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Pulmonary Artery; Pyrimidines; Rats; Rats, Wistar; Serotonin; Thiazoles

2012
Pharmacological characterization of TMEM16A currents.
    Channels (Austin, Tex.), 2014, Volume: 8, Issue:4

    Topics: Anoctamin-1; Anthracenes; Chloride Channels; HEK293 Cells; Humans; Ion Channel Gating; Kinetics; Neoplasm Proteins; Niflumic Acid; Patch-Clamp Techniques; Pyrimidines; Thiazoles

2014
Functional role of the Ca²⁺-activated Cl⁻ channel DOG1/TMEM16A in gastrointestinal stromal tumor cells.
    Experimental cell research, 2014, Aug-15, Volume: 326, Issue:2

    Topics: Anoctamin-1; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloride Channel Agonists; Chloride Channels; Electrophysiological Phenomena; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Neoplasm Proteins; Patch-Clamp Techniques; Proto-Oncogene Proteins c-kit; Pyrimidines; Thiazoles

2014
TRPC1 regulates calcium-activated chloride channels in salivary gland cells.
    Journal of cellular physiology, 2015, Volume: 230, Issue:11

    Topics: Animals; Anoctamin-1; Calcium; Calcium Signaling; Chloride Channels; Gene Expression Regulation; Humans; Mice; Mice, Knockout; Neoplasm Proteins; Niflumic Acid; Pyrimidines; Salivary Glands; Thiazoles; TRPC Cation Channels

2015
New selective inhibitors of calcium-activated chloride channels - T16A(inh) -A01, CaCC(inh) -A01 and MONNA - what do they inhibit?
    British journal of pharmacology, 2015, Volume: 172, Issue:16

    Topics: Animals; Cell Line; Cerebral Arteries; Chloride Channels; Female; In Vitro Techniques; Male; Mesenteric Arteries; Mice, Inbred C57BL; ortho-Aminobenzoates; Pyrimidines; Rats, Wistar; Thiazoles; Thiophenes; Vasodilator Agents

2015
Anoctamin-1 Cl(-) channels in nociception: activation by an N-aroylaminothiazole and capsaicin and inhibition by T16A[inh]-A01.
    Molecular pain, 2015, Sep-12, Volume: 11

    Topics: Action Potentials; Animals; Anoctamin-1; Capsaicin; Chloride Channels; Female; Ganglia, Spinal; HEK293 Cells; Humans; Mice, Inbred BALB C; Nociception; Pyrimidines; Thiazoles; Transfection

2015
Increased TMEM16A Involved in Alveolar Fluid Clearance After Lipopolysaccharide Stimulation.
    Inflammation, 2016, Volume: 39, Issue:2

    Topics: Acute Lung Injury; Animals; Anoctamin-1; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Chloride Channels; Disease Models, Animal; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Alveoli; Pulmonary Edema; Pyrimidines; RNA Interference; RNA, Small Interfering; Signal Transduction; Thiazoles

2016
Influence of intracellular Ca2+ and alternative splicing on the pharmacological profile of ANO1 channels.
    American journal of physiology. Cell physiology, 2016, 09-01, Volume: 311, Issue:3

    Topics: Alternative Splicing; Animals; Anoctamin-1; Benzbromarone; Calcium; Cell Line; Chloride Channels; Cytoplasm; HEK293 Cells; Humans; Mice; Patch-Clamp Techniques; Pyrimidines; Thiazoles

2016
Inhibition of calcium-activated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Anoctamin-1; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Neoplasm Proteins; Neoplasms, Glandular and Epithelial; Pyrimidines; RNA Interference; Signal Transduction; Thiazoles; Thiophenes; Time Factors; Transfection

2016
TMEM16A inhibition impedes capacitation and acquisition of hyperactivated motility in guinea pig sperm.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:7

    Topics: Acrosome Reaction; Animals; Anoctamin-1; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Chloride Channels; Chlorides; Guinea Pigs; Male; Niflumic Acid; Pyrimidines; Sperm Capacitation; Sperm Motility; Thiazoles

2018
Blockade of anoctamin-1 in injured and uninjured nerves reduces neuropathic pain.
    Brain research, 2018, 10-01, Volume: 1696

    Topics: Activating Transcription Factor 3; Animals; Anoctamin-1; Caspase 3; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; Injections, Spinal; Ligation; Neuralgia; Pyrimidines; Rats; Rats, Wistar; Spinal Nerves; Thiazoles

2018
Effects of the Calcium-Activated Chloride Channel Inhibitors T16Ainh-A01 and CaCCinh-A01 on Cardiac Fibroblast Function.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:2

    Topics: Actins; Animals; Anoctamin-1; Calcium; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Cells, Cultured; Chloride Channels; Chlorides; Collagen; Down-Regulation; Fibroblasts; Male; Myocytes, Cardiac; Pyrimidines; Rats; Rats, Sprague-Dawley; Thiazoles; Thiophenes

2018
Inhibition of TMEM16A impedes embryo implantation and decidualization in mice.
    Reproduction (Cambridge, England), 2018, Volume: 156, Issue:6

    Topics: Animals; Anoctamin-1; Cell Proliferation; Cells, Cultured; Decidua; Embryo Implantation; Female; Mice; Pregnancy; Pyrimidines; RNA Interference; RNA, Small Interfering; Signal Transduction; Stromal Cells; Thiazoles; Uterus

2018
Effects of Ca2+-Activated Cl- Channel ANO1inhibitors on Pacemaker Activity in Interstitial Cells of Cajal.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:6

    Topics: Animals; Anoctamin-1; Calcium; Cells, Cultured; Female; Interstitial Cells of Cajal; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; ortho-Aminobenzoates; Patch-Clamp Techniques; Pyrimidines; Thiazoles; Thiophenes

2018
Age‑associated variation in the expression and function of TMEM16A calcium‑activated chloride channels in the cochlear stria vascularis of guinea pigs.
    Molecular medicine reports, 2019, Volume: 20, Issue:2

    Topics: Aging; Animals; Anoctamin-1; Disease Models, Animal; Female; Galactose; Gene Expression Regulation; Guinea Pigs; Hearing; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Presbycusis; Pyrimidines; Stria Vascularis; Thiazoles

2019
Biochemical Inhibition of DOG1/TMEM16A Achieves Antitumoral Effects in Human Gastrointestinal Stromal Tumor Cells
    Anticancer research, 2019, Volume: 39, Issue:7

    Topics: Anoctamin-1; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Neoplasm Proteins; Pyrimidines; Thiazoles; Thiophenes

2019
TMEM16A Ca
    Molecular pharmacology, 2020, Volume: 98, Issue:1

    Topics: Animals; Anoctamin-1; Blood-Brain Barrier; Brain; Calcium; Cattle; Cell Line; Cell Movement; Cell Proliferation; Chloride Channels; Dose-Response Relationship, Drug; Endothelial Cells; HEK293 Cells; Humans; Male; Membrane Potentials; Mice; Niflumic Acid; Pyrimidines; Thiazoles

2020
[Effects of T16Ainh-A01 on the apoptosis and senescence of endothelial cells in the cochlea stria vascularis].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2020, Volume: 36, Issue:5

    Topics: Animals; Apoptosis; Cochlea; Endothelial Cells; Guinea Pigs; Pyrimidines; Stria Vascularis; Thiazoles

2020
The Role of TMEM16A/ERK/NK-1 Signaling in Dorsal Root Ganglia Neurons in the Development of Neuropathic Pain Induced by Spared Nerve Injury (SNI).
    Molecular neurobiology, 2021, Volume: 58, Issue:11

    Topics: Animals; Anoctamins; Butadienes; Chronic Pain; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Ligation; Male; Neuralgia; Nitriles; Nociception; Peroneal Nerve; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sensory Receptor Cells; Signal Transduction; Thiazoles; Tibial Nerve

2021
TMEM16A blockers T16Ainh-A01 and benzbromarone do not modulate the regulation of sweating and cutaneous vasodilatation in humans in vivo.
    Experimental physiology, 2022, Volume: 107, Issue:8

    Topics: Benzbromarone; Dimethyl Sulfoxide; Female; Humans; Pyrimidines; Skin; Sweating; Thiazoles; Vasodilation; Young Adult

2022