Compounds > thiazoles

Page last updated: 2024-08-21

thiazoles and stf 62247

thiazoles has been researched along with stf 62247 in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (33.33)	29.6817
2010's	4 (44.44)	24.3611
2020's	2 (22.22)	2.80

Authors

Authors	Studies
Chan, DA; Denny, WA; Giaccia, AJ; Hay, MP; Sutphin, PD; Turcotte, S	1
Giaccia, AJ; Sutphin, PD; Turcotte, S	1
Chan, DA; Giaccia, AJ	1
Anbalagan, S; Blick, C; Chan, DA; Ferguson, DJ; Hammond, EM; Hill, MA; Pires, IM	1
Barnett, D; Bouhamdani, N; Chute, IC; Cormier, K; Joy, A; Lamarre, S; Léger, D; Ouellette, R; Turcotte, S	1
Abou-El-Ardat, K; Fulda, S; Kögel, D; Mari, M; Meyer, N; Reggiori, F; van Wijk, SJL; Zielke, S	1
Bouhamdani, N; Comeau, D; Cormier, K; Turcotte, S	1
Bouhamdani, N; Coholan, A; Comeau, D; Cormier, K; Turcotte, S	1
Fulda, S; Kardo, S; Kinzler, MN; Kögel, D; Meyer, N; van Wijk, SJL; Zielke, S	1

Reviews

1 review(s) available for thiazoles and stf 62247

Article	Year
Targeting cancer cells by synthetic lethality: autophagy and VHL in cancer therapeutics. Cell cycle (Georgetown, Tex.), 2008, Volume: 7, Issue:19 Topics: Animals; Autophagy; Genes, Lethal; Humans; Models, Biological; Neoplasms; Proto-Oncogene Proteins c-ret; Pyridines; Thiazoles; Von Hippel-Lindau Tumor Suppressor Protein	2008

Other Studies

8 other study(ies) available for thiazoles and stf 62247

Article	Year
A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer cell, 2008, Jul-08, Volume: 14, Issue:1 Topics: Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Gene Silencing; Golgi Apparatus; Humans; Hydrogen-Ion Concentration; Hypoxia-Inducible Factor 1; Inhibitory Concentration 50; Kidney Neoplasms; Male; Mice; Mice, SCID; Microtubule-Associated Proteins; Molecular Structure; Phosphatidylinositol 3-Kinases; Protein Transport; Pyridines; Structure-Activity Relationship; Thiazoles; Time Factors; Transfection; Vacuoles; Von Hippel-Lindau Tumor Suppressor Protein; Yeasts	2008
Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death. Autophagy, 2008, Volume: 4, Issue:7 Topics: Antineoplastic Agents; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Humans; Kidney Neoplasms; Pyridines; Thiazoles; Von Hippel-Lindau Tumor Suppressor Protein	2008
Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 103, Issue:3 Topics: Antineoplastic Agents; Autophagy; Carcinoma, Renal Cell; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Humans; Kidney Neoplasms; Mutation; Pyridines; Radiation Dosage; Radiation Tolerance; Sirolimus; Thiazoles; Tumor Stem Cell Assay; Von Hippel-Lindau Tumor Suppressor Protein	2012
Quantitative proteomics to study a small molecule targeting the loss of von Hippel-Lindau in renal cell carcinomas. International journal of cancer, 2017, 08-15, Volume: 141, Issue:4 Topics: Carcinoma, Renal Cell; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Isotope Labeling; Kidney Neoplasms; Proteome; Proteomics; Pyridines; Signal Transduction; Thiazoles; Von Hippel-Lindau Tumor Suppressor Protein	2017
Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells. Cell death & disease, 2018, 09-24, Volume: 9, Issue:10 Topics: Apoptosis; Autophagosomes; Autophagy; Brain Neoplasms; Cell Line, Tumor; Endosomes; Glioblastoma; HT29 Cells; Humans; Loperamide; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Microscopy, Electron; Microtubule-Associated Proteins; Phosphorylation; Pimozide; Pyridines; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Thiazoles	2018
STF-62247 accumulates in lysosomes and blocks late stages of autophagy to selectively target von Hippel-Lindau-inactivated cells. American journal of physiology. Cell physiology, 2019, 05-01, Volume: 316, Issue:5 Topics: Autophagy; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Delivery Systems; HeLa Cells; Humans; Kidney Neoplasms; Lysosomes; Pyridines; Thiazoles; von Hippel-Lindau Disease	2019
Targeting lysosome function causes selective cytotoxicity in VHL-inactivated renal cell carcinomas. Carcinogenesis, 2020, 07-10, Volume: 41, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Renal Cell; Cell Proliferation; Humans; Kidney Neoplasms; Lysosomes; Mutation; Pyridines; Thiazoles; Tumor Cells, Cultured; Von Hippel-Lindau Tumor Suppressor Protein	2020
STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts. Scientific reports, 2020, 01-20, Volume: 10, Issue:1 Topics: Animals; Autophagic Cell Death; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Cell Line; Fibroblasts; Gene Knockout Techniques; Mice; Mitochondrial Proteins; Models, Biological; Pimozide; Proteolysis; Pyridines; Thiazoles	2020