Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and sr1001

thiazoles has been researched along with sr1001 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (73.68)24.3611
2020's5 (26.32)2.80

Authors

AuthorsStudies
Burris, TP; Drew, PD; Griffin, PR; Istrate, MA; Kamenecka, TM; Kumar, N; Lauer, JL; Liu, J; Nuhant, P; Roush, WR; Schürer, SC; Solt, LA; Vidović, D; Wagoner, G; Wang, Y; Xu, J1
Jetten, AM1
Ebisui, E; Hirase, H; Hisatsune, C; Mikoshiba, K; Mishima, T; Nagai, T; Takata, N1
Burris, TP; Griffin, PR; He, Y; Kamenecka, TM; Kumar, N; Solt, LA1
Beurel, E; Harrington, LE; Jope, RS1
Brazhe, A; Jensen, K; Jessen, SB; Lauritzen, M; Lind, BL; Mathiesen, C; Thomsen, K1
Banerjee, S; Burris, TP; Campbell, S; Kamenecka, TM; Solt, LA1
Kamata, Y; Negi, O; Ogawa, H; Sakaguchi, A; Takamori, K; Tominaga, M; Umehara, Y1
Chu, CQ; Lin, H; Liu, Y; Song, P; Xue, LJ; Zhao, Y1
Agrotis, A; Deliyanti, D; Talia, DM; Wilkinson-Berka, JL1
Coban, N; Erginel-Unaltuna, N; Gulec, C; Ozsait-Selcuk, B1
Kulkarni, P; Medishetti, R; Saxena, U; Sriram, D; Yellanki, S; Yogeeswari, P1
Burris, TP; Cunningham, DM; Ge, D; Huang, F; Liu, S; Ma, L; You, Z; Zhang, Q1
Choo, MK; Dai, J; Fisher, DE; Park, JM1
Li, C; Long, J; Peng, G; Xiao, P; Yang, H; Zeng, X1
Howell, SJ; Lee, CA; Lindstrom, SI; Tang, J; Taylor, BE; Taylor, PR; Taylor, ZRR; Zapadka, TE1
Antoine, B; Auclair, M; Capel, E; Fève, B; Roblot, N1
Chen, YE; Deng, W; Li, F; Wang, PU; Wang, S1
Chang, Q; Jing, H; Wang, J; Wu, X; Xu, Y; Zhang, Z1

Reviews

1 review(s) available for thiazoles and sr1001

ArticleYear
Targeting Th17 Cells with Small Molecules and Small Interference RNA.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Cell Differentiation; Digoxin; Heterocyclic Compounds, 4 or More Rings; Humans; Nuclear Receptor Subfamily 1, Group F, Member 3; Piperazines; Propanols; RNA, Small Interfering; SELEX Aptamer Technique; Sulfonamides; Th17 Cells; Thiazoles; Triterpenes; Ursolic Acid

2015

Other Studies

18 other study(ies) available for thiazoles and sr1001

ArticleYear
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.
    Nature, 2011, Apr-28, Volume: 472, Issue:7344

    Topics: Animals; Autoimmunity; Cell Differentiation; Drug Inverse Agonism; HEK293 Cells; Humans; Interleukin-17; Interleukins; Ligands; Mice; Mice, Inbred C57BL; Models, Molecular; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Sulfonamides; Th17 Cells; Thiazoles

2011
Immunology: A helping hand against autoimmunity.
    Nature, 2011, Apr-28, Volume: 472, Issue:7344

    Topics: Animals; Autoimmune Diseases; Autoimmunity; Cell Differentiation; Digoxin; Interleukin-17; Mice; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Sulfonamides; Th17 Cells; Thiazoles

2011
Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Dec-07, Volume: 31, Issue:49

    Topics: Acetylcholine; Action Potentials; Afferent Pathways; Aniline Compounds; Animals; Astrocytes; Atropine; Basal Nucleus of Meynert; Calcium Signaling; Cholinergic Agents; Chromatography, High Pressure Liquid; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Fluoresceins; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Knockout; Microdialysis; Muscarinic Antagonists; Nerve Growth Factors; Neuronal Plasticity; Neurons; Physical Stimulation; Piperazines; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serine; Somatosensory Cortex; Sulfonamides; Thiazoles; Vibrissae

2011
Identification of a selective RORγ ligand that suppresses T(H)17 cells and stimulates T regulatory cells.
    ACS chemical biology, 2012, Sep-21, Volume: 7, Issue:9

    Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Drug Discovery; HEK293 Cells; Humans; Interleukin-17; Ligands; Male; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 3; Sulfonamides; T-Lymphocytes, Regulatory; Thiazoles

2012
Inflammatory T helper 17 cells promote depression-like behavior in mice.
    Biological psychiatry, 2013, Apr-01, Volume: 73, Issue:7

    Topics: Animals; Depression; Gene Knock-In Techniques; Helplessness, Learned; Inflammation; Interleukin-17; Male; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3; Restraint, Physical; Sulfonamides; Th17 Cells; Thiazoles

2013
GABAA Receptor-Mediated Bidirectional Control of Synaptic Activity, Intracellular Ca2+, Cerebral Blood Flow, and Oxygen Consumption in Mouse Somatosensory Cortex In Vivo.
    Cerebral cortex (New York, N.Y. : 1991), 2015, Volume: 25, Issue:9

    Topics: Action Potentials; Animals; Biophysics; Calcium; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Isoxazoles; Mice; Oxygen Consumption; Partial Pressure; Pyridines; Receptors, GABA-A; Somatosensory Cortex; Sulfonamides; Thiazoles; Vibrissae; Zolpidem

2015
ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes.
    Endocrinology, 2015, Volume: 156, Issue:3

    Topics: Animals; Autoantibodies; Cytokines; Diabetes Mellitus, Type 1; Female; Forkhead Transcription Factors; Gene Expression Regulation; Hyperglycemia; Insulin; Mice; Mice, Inbred NOD; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Sulfonamides; Th17 Cells; Thiazoles

2015
Retinoid-related orphan receptor α is involved in induction of semaphorin 3A expression in normal human epidermal keratinocytes.
    Journal of dermatological science, 2015, Volume: 79, Issue:1

    Topics: Benzamides; Cells, Cultured; Cholesterol Esters; Gene Silencing; Humans; Keratinocytes; Nuclear Receptor Subfamily 1, Group F, Member 1; RNA, Messenger; Semaphorin-3A; Signal Transduction; Sulfonamides; Thiazoles; Triterpenes; Ursolic Acid

2015
Inhibition of the Nuclear Receptor RORγ and Interleukin-17A Suppresses Neovascular Retinopathy: Involvement of Immunocompetent Microglia.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Cells, Cultured; Digoxin; Disease Models, Animal; Ependymoglial Cells; Hyperoxia; Interleukin-17; Mice, Inbred C57BL; Microglia; Nuclear Receptor Subfamily 1, Group F, Member 3; Placenta Growth Factor; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Retinal Neovascularization; Retinopathy of Prematurity; Signal Transduction; Sulfonamides; Thiazoles; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2016
CYP19A1, MIF and ABCA1 genes are targets of the RORα in monocyte and endothelial cells.
    Cell biology international, 2017, Volume: 41, Issue:2

    Topics: Aromatase; ATP Binding Cassette Transporter 1; Cell Line; Chromatin Immunoprecipitation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Intramolecular Oxidoreductases; Ligands; Macrophage Migration-Inhibitory Factors; Monocytes; Nuclear Receptor Subfamily 1, Group F, Member 1; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Simvastatin; Sulfonamides; Thiazoles

2017
Novel Zebrafish EAE model: A quick in vivo screen for multiple sclerosis.
    Multiple sclerosis and related disorders, 2017, Volume: 11

    Topics: Animals; Dexamethasone; Dimethyl Fumarate; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Fingolimod Hydrochloride; Immunologic Factors; Phenotype; Sulfonamides; Thiazoles; Video Recording; Zebrafish

2017
Targeting Th17-IL-17 Pathway in Prevention of Micro-Invasive Prostate Cancer in a Mouse Model.
    The Prostate, 2017, Volume: 77, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Drug Monitoring; Immunologic Factors; Inflammation; Injections, Intraperitoneal; Interleukin-17; Male; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Prostate; Prostatic Neoplasms; Sulfonamides; Th17 Cells; Thiazoles; Treatment Outcome

2017
Topical ROR Inverse Agonists Suppress Inflammation in Mouse Models of Atopic Dermatitis and Acute Irritant Dermatitis.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:12

    Topics: Animals; Cell Differentiation; Cytokines; Dermatitis, Atopic; Dermatitis, Irritant; Disease Models, Animal; Eczema; Epidermis; Female; Inflammation; Keratinocytes; Ligands; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 1; Skin; Sulfonamides; Thiazoles

2017
Protective effects of resveratrol and SR1001 on hypoxia-induced pulmonary hypertension in rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2020, Aug-17, Volume: 42, Issue:6

    Topics: Animals; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Male; Protein Phosphatase 1; Pulmonary Artery; Rats; Resveratrol; rhoA GTP-Binding Protein; Sulfonamides; Th17 Cells; Thiazoles; Treatment Outcome

2020
RORγt Inhibitor-SR1001 Halts Retinal Inflammation, Capillary Degeneration, and the Progression of Diabetic Retinopathy.
    International journal of molecular sciences, 2020, May-17, Volume: 21, Issue:10

    Topics: Animals; Capillaries; Cell Death; Cell Survival; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drug Inverse Agonism; Endothelial Cells; Hyperglycemia; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Oxidative Stress; Retinal Vessels; Sulfonamides; Thiazoles

2020
Pharmacological modulation of RORα controls fat browning, adaptive thermogenesis, and body weight in mice.
    American journal of physiology. Endocrinology and metabolism, 2021, 02-01, Volume: 320, Issue:2

    Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Adult; Animals; Benzamides; Body Weight; Cell Transdifferentiation; Cells, Cultured; Cold-Shock Response; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nuclear Receptor Subfamily 1, Group F, Member 1; Sulfonamides; Thermogenesis; Thiazoles; Thiophenes

2021
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice.
    Acta biochimica et biophysica Sinica, 2021, Oct-12, Volume: 53, Issue:10

    Topics: Animals; Apoptosis; Cell Line, Tumor; Clostridium Infections; Colon; Disease Models, Animal; Intestinal Mucosa; Janus Kinase 2; Male; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 3; Recurrence; STAT3 Transcription Factor; Sulfonamides; Th17 Cells; Thiazoles

2021
RORγt inhibitor SR1001 alleviates acute pancreatitis by suppressing pancreatic IL-17-producing Th17 and γδ-T cells in mice with ceruletide-induced pancreatitis.
    Basic & clinical pharmacology & toxicology, 2021, Volume: 129, Issue:5

    Topics: Acute Disease; Adult; Aged; Animals; Case-Control Studies; Ceruletide; Disease Models, Animal; Disease Progression; Female; Humans; Interleukin-17; Intraepithelial Lymphocytes; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Middle Aged; Nuclear Receptor Subfamily 1, Group F, Member 3; Pancreatitis; Sulfonamides; Th17 Cells; Thiazoles

2021