thiazoles has been researched along with sr 146131 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachy, A; Bignon, E; Boigegrain, R; Brodin, R; Cottineau, M; Gully, D; Herbert, JM; Keane, P; Labie, C; Le Fur, G; Maffrand, JP; Molimard, JC; Olliero, D; Oury-Donat, F; Pascal, M; Petereau, C; Prabonnaud, V; Rockstroh, MP; Schaeffer, P; Servant, O; Soubrié, P; Thurneyssen, O | 1 |
| Alonso, R; Arnone, M; Bignon, E; Boigegrain, R; Brodin, R; Gueudet, C; Héaulme, M; Keane, P; Landi, M; Le Fur, G; Maffrand, JP; Molimard, JC; Olliero, D; Pascal, M; Poncelet, M; Seban, E; Simiand, J; Soubrié, P | 1 |
| Carillon, C; Delpech, B; Ferrara, P; Gouldson, P; Le Fur, G; Legoux, P; Shire, D | 2 |
| Carillon, C; Dumont, X; Ferrara, P; Gouldson, P; Le Fur, G; Legoux, P; Shire, D | 1 |
| Bachy, A; Bignon, E; Herbert, JM; Keane, PE; Laplace, MC; Nestor, AL; Prabonnaud, V; Schaeffer, P | 1 |
| Archer, E; Behrendt, R; Bignon, E; Escrieut, C; Fourmy, D; Gigoux, V; Maigret, B; Moroder, L; Pradayrol, L; Silvente-Poirot, S; Verrier, S | 1 |
| Feifel, D; Shilling, PD | 1 |
| Caicoya, E; Cano, V; Ruiz-Gayo, M | 1 |
| Archer-Lahlou, E; Dufresne, M; Escrieut, C; Fourmy, D; Maigret, B; Moroder, L; Pradayrol, L; Seva, C; Tikhonova, I | 1 |
| Berger, R; Chen, Z; Edmondson, SD; Hansen, AR; Harper, B; Holt, TG; Hubert, J; Lee, SJ; Macneil, DJ; Pan, J; Qian, S; Reitman, ML; Strack, AM; Weber, AE; Weingarth, DT; Wolff, M; Zhu, C | 1 |
| Abagyan, R; Christopoulos, A; Desai, AJ; Lam, PCH; Mechin, I; Miller, LJ; Nagarajan, K; Nair, A; Orry, A; Sexton, PM; Valant, C; Wootten, D | 1 |
12 other study(ies) available for thiazoles and sr 146131
| Article | Year |
|---|---|
SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies.
Topics: 3T3 Cells; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Devazepide; DNA-Binding Proteins; Early Growth Response Protein 1; Genes, Immediate-Early; Hormone Antagonists; Humans; Immediate-Early Proteins; Indoleacetic Acids; Indoles; Inosine Monophosphate; Mice; Neuroblastoma; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Thiazoles; Transcription Factors; Tumor Cells, Cultured | 1999 |
SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization.
Topics: Animals; Appetite Stimulants; Callithrix; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Eating; Female; Gallbladder Emptying; Gastric Acid; Gastric Emptying; Gerbillinae; Indoles; Male; Mice; Motor Activity; Neuropeptide Y; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Species Specificity; Stereotyped Behavior; Thiazoles | 1999 |
Contrasting roles of leu(356) in the human CCK(1) receptor for antagonist SR 27897 and agonist SR 146131 binding.
Topics: Animals; Binding Sites; COS Cells; Hormone Antagonists; Humans; Indoleacetic Acids; Indoles; Leucine; Point Mutation; Receptors, Cholecystokinin; Sincalide; Thiazoles | 1999 |
Essential role of extracellular charged residues of the human CCK(1) receptor for interactions with SR 146131, SR 27897 and CCK-8S.
Topics: Amino Acid Sequence; Animals; COS Cells; Dose-Response Relationship, Drug; Humans; Indoleacetic Acids; Indoles; Inositol Phosphates; Molecular Sequence Data; Mutation; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship; Thiazoles | 2000 |
Characterisation of the effects of SR146131, a novel non-peptide CCK(1) receptor agonist, on IMR-32 human neuroblastoma cells.
Topics: Benzodiazepinones; Binding, Competitive; Calcium; Devazepide; Dose-Response Relationship, Drug; Humans; Indoles; Iodine Radioisotopes; Neuroblastoma; Phenylurea Compounds; Phosphatidylinositols; Radioligand Assay; Receptors, Cholecystokinin; Sincalide; Thiazoles; Tumor Cells, Cultured | 2000 |
The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK(1) receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; COS Cells; Hormone Antagonists; Humans; Indoleacetic Acids; Indoles; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Protein Structure, Tertiary; Receptors, Cholecystokinin; Thiazoles | 2000 |
The biologically crucial C terminus of cholecystokinin and the non-peptide agonist SR-146,131 share a common binding site in the human CCK1 receptor. Evidence for a crucial role of Met-121 in the activation process.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cholecystokinin; COS Cells; Dose-Response Relationship, Drug; Humans; Indoles; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Thiazoles; Transfection | 2002 |
SR146131, a cholecystokinin-A receptor agonist, antagonizes prepulse inhibition deficits produced by dizocilpine and DOI.
Topics: Amphetamine; Amphetamines; Animals; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Indoles; Inhibition, Psychological; Male; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reflex, Startle; Thiazoles | 2002 |
Effect of peripheral cholecystokinin receptor agonists on c-Fos expression in brain sites mediating food consumption in rats.
Topics: Animals; Antigens, Neoplasm; Brain; Brain Stem; Cell Adhesion Molecules; Cholecystokinin; Eating; Gene Expression Regulation; Hypothalamus; Indoles; Male; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Cholecystokinin; Satiety Response; Tetragastrin; Thiazoles | 2003 |
Modeled structure of a G-protein-coupled receptor: the cholecystokinin-1 receptor.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Benzodiazepinones; Binding Sites; Chlorocebus aethiops; Cholecystokinin; COS Cells; Devazepide; Humans; Indoleacetic Acids; Indoles; Ligands; Lipid Metabolism; Lipids; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylurea Compounds; Protein Conformation; Receptor, Cholecystokinin A; Rhodopsin; Sequence Homology, Amino Acid; Thiazoles | 2005 |
2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.
Topics: Animals; Anti-Obesity Agents; Benzodiazepines; Chemokines, CC; Humans; Indoles; Methylamines; Mice; Obesity; Piperazine; Piperazines; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Thiazoles | 2008 |
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor.
Topics: Allosteric Regulation; Allosteric Site; Animals; Cell Line; CHO Cells; Cholecystokinin; Cricetulus; Indoles; Mutagenesis, Site-Directed; Peptides; Receptors, Cholecystokinin; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles | 2019 |