thiazoles has been researched along with sphingosine 1-phosphate in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Desai, NN; Mattie, ME; Olivera, A; Spiegel, S; Zhang, H | 1 |
| Endo, A; Hasegawa, T; Koide, Y; Mochizuki, N; Nakagawa, M; Nishida, A; Takahashi, A | 1 |
| Becker, KP; Bielawski, J; Johnson, KR; Johnson, KY; Mao, C; Obeid, LM | 1 |
| Gonska, H; Kim, DS; Kleuser, B; Manggau, M; Sauer, B; Schäfer-Korting, M; Schraut, C | 1 |
| Coelho, RP; Goparaju, SK; Jolly, PS; Maceyka, M; Saini, HS; Sato-Bigbee, C; Spiegel, S | 1 |
| French, KJ; Keller, SN; Smith, CD; Upson, JJ; Yun, JK; Zhuang, Y | 1 |
| Chen, S; Sun, J; Yan, G; You, B | 1 |
| Jahangeer, S; Kotani, Y; Kuramoto, E; Nakamura, S; Nishimura, Y; Nishiuma, T; Okada, T | 1 |
| Baur, F; Fozard, JR; Trifilieff, A | 1 |
| Chiba, Y; Misawa, M; Sakai, H; Takeuchi, H | 1 |
| Highkin, MK; Lamarr, WA; Masferrer, JL; Munie, GE; Nagiec, MM; Nemirovskiy, OV; Rains, JW; Yates, MP | 1 |
| Kanno, T; Nishizaki, T | 1 |
| Fox, TE; Gowda, R; Hengst, J; Madhunapantula, SV; Robertson, GP; Yun, JK | 1 |
| Bauer, Y; Bolli, MH; Gatfield, J; Killer, N; Menyhart, K; Nayler, O; Renault, B; Sobel, K; Steiner, B; Studer, R | 1 |
| Buist-Homan, M; Combettes, L; de Boer, JF; Faber, KN; Karimian, G; Klappe, K; Kok, JW; Moshage, H; Schmidt, M; Tietge, UJ; Tordjmann, T | 1 |
| He, HW; Shao, RG; Zhang, CX | 1 |
| Bittman, R; Ohotski, J; Pyne, NJ; Pyne, S; Rosen, H | 1 |
| Bolli, MH; Gatfield, J; Monnier, L; Nayler, O; Steiner, B; Studer, R | 1 |
| Bieberich, E; Bryant, L; Chen, C; Chen, Z; Cuzzocrea, S; Doyle, T; Esposito, E; Janes, K; Kamocki, K; Li, C; Little, JW; Neumann, WL; Nicol, G; Obeid, L; Petrache, I; Salvemini, D; Snider, A | 1 |
| Burkhardt, R; Ceglarek, U; Nofer, JR; Potì, F; Simoni, M | 1 |
| Arai, K; Herr, DR; Lai, MK; Torta, F; Wenk, MR; Wong, PT; Yang, Y | 1 |
| Sadik, CD; Thieme, M; Zillikens, D | 1 |
| Angioni, C; Brüne, B; Ferreirós, N; Giegerich, AK; Knape, T; Kuchler, L; Schmidt, MV; Sha, LK; von Knethen, A; Weigert, A | 1 |
| Cao, Y; Gao, J; Hao, Y; Sun, C; Wang, J; Wu, H; Wu, L; Xia, W; Zhang, Q | 1 |
2 review(s) available for thiazoles and sphingosine 1-phosphate
| Article | Year |
|---|---|
[Sphingosine kinase 1 and tumor].
Topics: Amino Alcohols; Animals; Apoptosis; Cell Movement; Cell Proliferation; Ceramides; Enzyme Activation; Enzyme Inhibitors; Humans; Lysophospholipids; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Sphingosine; Thiazoles | 2013 |
Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation.
Topics: Animals; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Lymphocytes; Lysophospholipids; Receptors, Lymphocyte Homing; Receptors, Lysophospholipid; Skin Diseases; Sphingosine; Thiazoles | 2017 |
22 other study(ies) available for thiazoles and sphingosine 1-phosphate
| Article | Year |
|---|---|
Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation.
Topics: 3T3 Cells; Animals; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Lysophospholipids; Mice; Phosphatidate Phosphatase; Phosphatidic Acids; Phospholipase D; Pyrimidinones; Sphingosine; Thiazoles | 1992 |
Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships.
Topics: Databases, Factual; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Lysophospholipids; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; NF-KappaB Inhibitor alpha; Quantitative Structure-Activity Relationship; Receptors, Lysophospholipid; Sphingosine; Stereoisomerism; Thiazines; Thiazoles | 2002 |
Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability.
Topics: Amino Acid Sequence; Animals; Blotting, Northern; Cell Division; Cell Line; Cell Survival; Cloning, Molecular; Coloring Agents; DNA, Complementary; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Humans; Lysophospholipids; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Protein Isoforms; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sequence Homology, Amino Acid; Signal Transduction; Sphingolipids; Sphingosine; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 2003 |
Sphingosine 1-phosphate is involved in cytoprotective actions of calcitriol in human fibroblasts and enhances the intracellular Bcl-2/Bax rheostat.
Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Calcitriol; Cell Proliferation; Cell Survival; Cells, Cultured; Ceramides; DNA; Down-Regulation; Fibroblasts; Flow Cytometry; Genes, bcl-2; Humans; Immunoblotting; Lysophospholipids; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
Novel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitors.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Membrane; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Drug Interactions; Gene Expression Regulation; In Situ Nick-End Labeling; Lysophospholipids; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Neurotrophin 3; Oligodendroglia; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Sphingosine; Stem Cells; Thiazoles; Thiazolidinediones; Thiones; Time Factors | 2005 |
Antitumor activity of sphingosine kinase inhibitors.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Half-Life; Lysophospholipids; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Multidrug Resistance-Associated Proteins; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Sphingosine; Thiazoles | 2006 |
Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Lysophospholipids; Neovascularization, Physiologic; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Thiazoles | 2008 |
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.
Topics: Administration, Inhalation; Aniline Compounds; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemokines, CC; Disease Models, Animal; Enzyme Inhibitors; Goblet Cells; Humans; Hyperplasia; Interleukins; Lysophospholipids; Mice; Mice, Inbred C57BL; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Respiratory Mucosa; Sphingosine; Thiazoles | 2008 |
Role of sphingosine-1-phosphate (S1P) and the S1P(2) receptor in allergen-induced, mast cell-dependent contraction of rat lung parenchymal strips.
Topics: Acetates; Adenosine; Allergens; Animals; Bronchoconstriction; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Subcutaneous; Leukotriene Antagonists; Lung; Lysophospholipids; Male; Mast Cells; Methysergide; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Pyrazoles; Pyridines; Quinolines; Rats; Rats, Inbred BN; Receptors, Lysosphingolipid; Serotonin; Serotonin Antagonists; Signal Transduction; Sphingosine; Sulfides; Thiazoles | 2009 |
SKI-II, an inhibitor of sphingosine kinase, ameliorates antigen-induced bronchial smooth muscle hyperresponsiveness, but not airway inflammation, in mice.
Topics: Animals; Antigens; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Immunoglobulin E; Interleukin-13; Interleukin-4; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Phosphotransferases (Alcohol Group Acceptor); Sphingosine; Thiazoles | 2010 |
High-throughput screening assay for sphingosine kinase inhibitors in whole blood using RapidFire® mass spectrometry.
Topics: Aminophenols; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Kinetics; Lysophospholipids; Mass Spectrometry; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingosine; Thiazoles | 2011 |
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Lysophospholipids; Male; Maleimides; Mossy Fibers, Hippocampal; Neurons; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Lysosphingolipid; Sphingosine; Suramin; Thiazoles | 2011 |
Targeting sphingosine kinase-1 to inhibit melanoma.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Fibroblasts; G1 Phase Cell Cycle Checkpoints; Humans; Lysophospholipids; Melanocytes; Melanoma; Mice; Molecular Targeted Therapy; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resting Phase, Cell Cycle; RNA, Small Interfering; Skin Neoplasms; Sphingosine; Staurosporine; Thiazoles; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling.
Topics: Actins; Animals; CHO Cells; Cricetinae; Cricetulus; Down-Regulation; Extracellular Matrix; Humans; Lung; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myofibroblasts; Organophosphates; Oxadiazoles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; Receptors, Lysosphingolipid; Signal Transduction; Smad2 Protein; Smad3 Protein; Sphingosine; Thiazoles; Thiophenes; Transforming Growth Factor beta1 | 2013 |
Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis.
Topics: Animals; Apoptosis; Bile Acids and Salts; Blotting, Western; Caspase 3; Cells, Cultured; Detergents; Gastrointestinal Agents; Glycochenodeoxycholic Acid; Hepatocytes; Lysophospholipids; Male; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Lysosphingolipid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sphingosine; Thiazoles | 2013 |
Sphingosine kinase 2 prevents the nuclear translocation of sphingosine 1-phosphate receptor-2 and tyrosine 416 phosphorylated c-Src and increases estrogen receptor negative MDA-MB-231 breast cancer cell growth: The role of sphingosine 1-phosphate receptor
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; CSK Tyrosine-Protein Kinase; Female; Fingolimod Hydrochloride; Humans; Lysophospholipids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Receptors, Estrogen; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; src-Family Kinases; Thiazoles; Tyrosine | 2014 |
Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling.
Topics: Arrestins; Autoimmune Diseases; beta-Arrestins; Cell Line, Tumor; GTP-Binding Protein alpha Subunits, Gi-Go; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Lysophospholipids; Membrane Proteins; Phosphoric Monoester Hydrolases; Protein Transport; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; T-Lymphocytes; Thiazoles | 2014 |
The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.
Topics: Anilides; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Enzyme Activation; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Indans; Lysophospholipids; Male; Neuralgia; Organophosphonates; Oxadiazoles; Paclitaxel; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Thiazoles; Thiophenes | 2014 |
SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Biomarkers; Cholesterol, Dietary; Cholesterol, HDL; Diet, Western; Disease Models, Animal; Enzyme Inhibitors; Female; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Lysophospholipids; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Receptors, LDL; Risk Factors; Sphingosine; Thiazoles; Time Factors; Triglycerides; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2015 |
Sphingosine kinase inhibition ameliorates chronic hypoperfusion-induced white matter lesions.
Topics: Animals; Brain; Carotid Artery Diseases; Cells, Cultured; Chronic Disease; Enzyme Inhibitors; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Sphingosine; Thiazoles; White Matter | 2016 |
Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis.
Topics: Aminophenols; Animals; Apoptosis; Atrophy; Cecum; Disease Models, Animal; Interleukin-6; Lymphocytosis; Lymphopenia; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Sepsis; Sphingosine; Thiazoles; Thymocytes; Thymus Gland | 2017 |
Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.
Topics: Analysis of Variance; Animals; Apoptosis; Autistic Disorder; Autophagy; Biomarkers; Disease Models, Animal; Hippocampus; Humans; Lysophospholipids; Male; Memory Disorders; Neurons; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Signal Transduction; Spatial Learning; Sphingosine; Thiazoles; Valproic Acid | 2018 |