thiazoles has been researched along with sp 203 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, AK; Innis, RB; Patterson, VM; Pike, VW; Siméon, FG; Zoghbi, SS | 1 |
| Brownell, AL; Pellegrino, D; Tueckmantel, W; Wang, JQ; Zhu, A | 1 |
| Brown, AK; Innis, RB; Kannan, P; Liow, JS; Pike, VW; Shetty, HU; Siméon, FG; Zoghbi, SS | 1 |
| Brown, AK; Fujita, M; Innis, RB; Kimura, Y; Kreisl, WC; Liow, JS; Pike, VW; Siméon, FG; Taku, A; Zoghbi, SS | 1 |
| Fujita, M; Hatazawa, J; Innis, RB; Kimura, Y; Mozley, PD; Pike, VW; Siméon, FG | 1 |
| Fujita, M; Hatazawa, J; Innis, RB; Kimura, Y; Pike, VW; Siméon, FG; Zhang, Y; Zoghbi, SS | 1 |
| Gladding, RL; Hong, J; Innis, RB; Liow, JS; Pike, VW; Siméon, FG; Zhang, Y; Zoghbi, SS | 1 |
| Fujita, M; Innis, RB; Kimura, Y; Lohith, TG; Lyoo, CH; Morse, CL; Pike, VW; Siméon, FG; Tsujikawa, T; Veronese, M; Zoghbi, SS | 1 |
1 trial(s) available for thiazoles and sp 203
| Article | Year |
|---|---|
Biodistribution and radiation dosimetry of a positron emission tomographic ligand, 18F-SP203, to image metabotropic glutamate subtype 5 receptors in humans.
Topics: Adult; Bone and Bones; Bone Marrow; Female; Fluorine Radioisotopes; Halogenation; Humans; Ligands; Male; Nitriles; Positron-Emission Tomography; Radiation Dosage; Radiometry; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2010 |
7 other study(ies) available for thiazoles and sp 203
| Article | Year |
|---|---|
Synthesis and simple 18F-labeling of 3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile as a high affinity radioligand for imaging monkey brain metabotropic glutamate subtype-5 receptors with positron emission tomography.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Humans; Macaca mulatta; Nitriles; Positron-Emission Tomography; Radioligand Assay; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2007 |
Synthesis and preliminary biological evaluation of 3-[(18)F]fluoro-5-(2-pyridinylethynyl)benzonitrile as a PET radiotracer for imaging metabotropic glutamate receptor subtype 5.
Topics: Animals; Benzimidazoles; Brain; Evaluation Studies as Topic; Excitatory Amino Acid Antagonists; Male; Nitriles; Piperidines; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles; Tissue Distribution; Whole Body Imaging | 2007 |
Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 receptors with positron emission tomography, occurs by glutathionylation in rat br
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Fluorine Radioisotopes; Glutathione Transferase; Halogenation; Mass Spectrometry; Nitriles; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles; Urine | 2008 |
Metabotropic glutamate subtype 5 receptors are quantified in the human brain with a novel radioligand for PET.
Topics: Adult; Brain; Female; Fluorine Radioisotopes; Humans; Male; Metabolic Clearance Rate; Nitriles; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles; Tissue Distribution | 2008 |
Quantification of metabotropic glutamate subtype 5 receptors in the brain by an equilibrium method using 18F-SP203.
Topics: Adult; Brain; Brain Chemistry; Female; Fluorine Radioisotopes; Humans; Image Processing, Computer-Assisted; Ligands; Male; Middle Aged; Models, Statistical; Nitriles; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reproducibility of Results; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2012 |
Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors.
Topics: Animals; Brain; Carbon Radioisotopes; Humans; Ligands; Macaca mulatta; Male; Nitriles; Radioactive Tracers; Radionuclide Imaging; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2012 |
Comparison of two PET radioligands, [
Topics: Adult; Brain; Carbon Radioisotopes; Female; Healthy Volunteers; Humans; Image Processing, Computer-Assisted; Ligands; Male; Models, Biological; Nitriles; Positron-Emission Tomography; Pyridines; Radionuclide Imaging; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; RNA, Messenger; Thiazoles; Tissue Distribution; Whole Body Imaging | 2017 |