Page last updated: 2024-08-21

thiazoles and simvastatin

thiazoles has been researched along with simvastatin in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's11 (57.89)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, MK; Lin, JC1
Caldwell, SH; Hespenheide, EE; von Borstel, RW1
Amin, RD; Dilzer, S; Gagliano, K; Kuznetsova, O; Lasseter, KC; Liu, L; Musser, B; Prueksaritanont, T; Roadcap, BA; Rogers, JD; Vega, JM; Zhao, J1
Demant, T1
Abourjaily, HM; Alsheikh-Ali, AA; Karas, RH1
Hoogwerf, BJ; Nambi, V; Sprecher, DL1
Lawrence, I1
Giehl, K; Goppelt-Struebe, M; Graness, A; Iwanciw, D; Ott, C1
Berger, JP; Biswas, C; Chao, YS; Doebber, TW; Ippolito, MC; Kelly, LJ; Li, Y; Meurer, R; Moller, DE; Wang, PR; Wright, SD; Wu, MS; Zhou, G1
Crisby, M; Lindberg, C; Schultzberg, M; Winblad, B1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX1
Fonseca, AC; Oliveira, CR; Pereira, CM; Proença, T; Resende, R1
Dean, IN; Rawal, SY; Stein, SH; Tipton, DA1
Alexander, R; Bettica, P; Gomeni, R; Nucci, G; Pyke, C; Ratti, E; Squassante, L; Zamuner, S1
Choi, GW; Kim, EC; Lee, SI; Lee, SY; Min, KS; Park, JH; Park, SH1
Gupta, A; Kalonia, H; Kumar, A; Mishra, J; Sharma, N1
Saewong, S; Thammasitboon, K; Wattanaroonwong, N1
Hasunuma, T; Jang, IJ; Kaneko, M; Kaniwa, N; Kawai, S; Saito, Y; Takeuchi, M; Tohkin, M; Uyama, Y; Watanabe, H; Yamazoe, Y; Yimin, C1
Coban, N; Erginel-Unaltuna, N; Gulec, C; Ozsait-Selcuk, B1

Reviews

1 review(s) available for thiazoles and simvastatin

ArticleYear
A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia.
    Cleveland Clinic journal of medicine, 2002, Volume: 69, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Male; Metabolic Syndrome; Metformin; Motor Activity; Obesity; Simvastatin; Thiazoles; Thiazolidinediones; Weight Loss

2002

Trials

3 trial(s) available for thiazoles and simvastatin

ArticleYear
Interactions between simvastatin and troglitazone or pioglitazone in healthy subjects.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:5

    Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Chromans; Confidence Intervals; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Female; Headache; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Simvastatin; Thiazoles; Thiazolidinediones; Troglitazone

2001
Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Arousal; Benzofurans; Cognition; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Half-Life; Humans; Hypnotics and Sedatives; Male; Middle Aged; Orexin Receptors; Polysomnography; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Simvastatin; Single-Blind Method; Sleep; Sleep Stages; Thiazoles; Wakefulness

2012
Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians.
    British journal of clinical pharmacology, 2016, Volume: 81, Issue:6

    Topics: Adult; Asian People; Cytochrome P-450 CYP2C9; Fluoroquinolones; Glucuronosyltransferase; Humans; Liver-Specific Organic Anion Transporter 1; Male; Meloxicam; Moxifloxacin; Polymorphism, Genetic; Simvastatin; Thiazines; Thiazoles; White People; Young Adult

2016

Other Studies

15 other study(ies) available for thiazoles and simvastatin

ArticleYear
A drug interaction between troglitazone and simvastatin.
    Diabetes care, 1999, Volume: 22, Issue:12

    Topics: Cholesterol, LDL; Chromans; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Retrospective Studies; Simvastatin; Thiazoles; Thiazolidinediones; Troglitazone

1999
Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:2

    Topics: Aged; Anticholesteremic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Chromans; Diabetes Mellitus, Type 2; Disease Progression; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypoglycemic Agents; Liver Cirrhosis; Myositis; Simvastatin; Thiazoles; Thiazolidinediones; Troglitazone

2001
[Diabetic dyslipoproteinemia: physiopathological bases and treatment prospects].
    Fortschritte der Medizin. Originalien, 2001, Volume: 119, Issue:1

    Topics: Anticholesteremic Agents; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Chromans; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Hyperlipoproteinemias; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Risk Factors; Simvastatin; Thiazoles; Thiazolidinediones; Troglitazone

2001
Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and acarbose).
    The American journal of cardiology, 2002, Jun-01, Volume: 89, Issue:11

    Topics: Acarbose; Adverse Drug Reaction Reporting Systems; Anticholesteremic Agents; Atorvastatin; Chromans; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Pyrroles; Simvastatin; Sulfonylurea Compounds; Thiazoles; Thiazolidinediones; Troglitazone

2002
Continuing education.
    Diabetic medicine : a journal of the British Diabetic Association, 2003, Volume: 20 Suppl 1

    Topics: Adult; Aged; Anticholesteremic Agents; Coronary Disease; Diabetic Angiopathies; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Simvastatin; Thiazoles; Thiazolidinediones

2003
Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Actins; Amides; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Colchicine; Connective Tissue Growth Factor; Cytochalasin D; Cytoskeleton; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Nocodazole; Paclitaxel; Pyridines; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin; Stress, Mechanical; Thiazoles; Thiazolidines

2003
MK-0767, a novel dual PPARalpha/gamma agonist, displays robust antihyperglycemic and hypolipidemic activities.
    Biochemical and biophysical research communications, 2004, May-28, Volume: 318, Issue:2

    Topics: Animals; Benzamides; Blood Glucose; Chlorocebus aethiops; Cholesterol; COS Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Male; Mesocricetus; Mice; Mice, Obese; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Simvastatin; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcriptional Activation; Triglycerides

2004
Effects of statins on microglia.
    Journal of neuroscience research, 2005, Oct-01, Volume: 82, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Atorvastatin; Cell Death; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; L-Lactate Dehydrogenase; Lipopolysaccharides; Microglia; Peptide Fragments; Pyrroles; Rats; Simvastatin; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles

2005
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles

2008
Neuroprotective effects of statins in an in vitro model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2009, Volume: 17, Issue:3

    Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Calcium; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholesterol; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Extracellular Signal-Regulated MAP Kinases; In Situ Nick-End Labeling; Lovastatin; Neurons; Neuroprotective Agents; Oncogene Protein v-akt; Peptide Fragments; Rats; Rats, Wistar; Reactive Oxygen Species; Simvastatin; Tetrazolium Salts; Thiazoles; Time Factors

2009
Statins regulate interleukin-1β-induced RANKL and osteoprotegerin production by human gingival fibroblasts.
    Journal of periodontal research, 2011, Volume: 46, Issue:4

    Topics: Atorvastatin; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Serum-Free; Fibroblasts; Gingiva; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Osteoprotegerin; Pyrroles; RANK Ligand; Simvastatin; Temperature; Tetrazolium Salts; Thiazoles; Time Factors

2011
Effects of simvastain and enamel matrix derivative on Portland cement with bismuth oxide-induced growth and odontoblastic differentiation in human dental pulp cells.
    Journal of endodontics, 2012, Volume: 38, Issue:3

    Topics: Alkaline Phosphatase; Aluminum Compounds; Anthraquinones; Biocompatible Materials; Bismuth; Calcification, Physiologic; Calcium Compounds; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Coloring Agents; Core Binding Factor Alpha 1 Subunit; Dental Cements; Dental Enamel Proteins; Dental Pulp; Drug Combinations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Materials Testing; Odontoblasts; Odontogenesis; Osteocalcin; Osteopontin; Oxides; Pulp Capping and Pulpectomy Agents; Reverse Transcriptase Polymerase Chain Reaction; Silicates; Simvastatin; Sp7 Transcription Factor; Tetrazolium Salts; Thiazoles; Transcription Factors

2012
Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.
    Brain research, 2012, Aug-30, Volume: 1471

    Topics: Amphetamine; Analysis of Variance; Animals; Atorvastatin; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Malondialdehyde; Mitochondria; Motor Activity; NADH Dehydrogenase; Nitrites; Oxidopamine; Parkinsonian Disorders; Pyrroles; Rats; Rats, Wistar; Simvastatin; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha

2012
Simvastatin induces apoptosis and disruption of the actin cytoskeleton in human dental pulp cells and periodontal ligament fibroblasts.
    Archives of oral biology, 2013, Volume: 58, Issue:8

    Topics: Actin Cytoskeleton; Adolescent; Adult; Apoptosis; Cell Culture Techniques; Cell Nucleus; Cell Shape; Cell Survival; Cells, Cultured; Coloring Agents; Dental Pulp; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Periodontal Ligament; Phalloidine; Simvastatin; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult

2013
CYP19A1, MIF and ABCA1 genes are targets of the RORα in monocyte and endothelial cells.
    Cell biology international, 2017, Volume: 41, Issue:2

    Topics: Aromatase; ATP Binding Cassette Transporter 1; Cell Line; Chromatin Immunoprecipitation; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Intramolecular Oxidoreductases; Ligands; Macrophage Migration-Inhibitory Factors; Monocytes; Nuclear Receptor Subfamily 1, Group F, Member 1; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Simvastatin; Sulfonamides; Thiazoles

2017