thiazoles has been researched along with sesquiterpenes in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (5.05) | 18.7374 |
| 1990's | 10 (10.10) | 18.2507 |
| 2000's | 48 (48.48) | 29.6817 |
| 2010's | 30 (30.30) | 24.3611 |
| 2020's | 6 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Buckley, S; DeLoach, JR; Holt, PS; Norman, JO | 1 |
| Hayes, MA; Kim, HL; Merrill, JC; Murray, CA; Safe, S | 1 |
| DeLoach, JR; Holt, PS | 1 |
| Buckley, S; Deloach, JR; Holt, PS | 1 |
| Kim, HL; Merrill, J; Safe, S | 1 |
| Amade, P; Delescluse, C; Durand-Clément, M; Fournier, V; Lemée, R; Parent-Massin, D; Pesando, D | 1 |
| Edwards, G; Fishwick, J; McLean, WG; Smith, SL; Ward, SA | 1 |
| Basnet, P; Jung, WT; Kadota, S; Namba, T; Park, HJ | 1 |
| Last, RL; Zhao, J | 1 |
| Beekman, AC; Konings, AW; Pras, N; Schmidt, TJ; van Uden, W; Wikström, HV; Woerdenbag, HJ | 1 |
| Barentsen, AR; Beekman, AC; el-Feraly, FS; Galal, AM; Konings, AW; Pras, N; Van Uden, W; Wikström, HV; Woerdenbag, HJ | 1 |
| Konwalinka, G; Stuppner, H; Tiefenthaler, M; Zidorn, C | 1 |
| Broekaert, WF; Eggermont, K; Nelissen, I; Thomma, BP | 1 |
| Ma, W; Novotny, MV; Wiesler, D; Zídek, L | 1 |
| Glazebrook, J; Tootle, TL; Zhou, N | 1 |
| Khan, AQ; Pedras, MS | 1 |
| Dzurilla, M; Harada, N; Kutschy, P; Monde, K; Suchy, M; Takasugi, M | 1 |
| Buchler, IP; Cohn, ST; Cox, MM; Langenhan, JM; Messerschmidt, NB; Park, K; Romo, D; Rzasa, RM; Schmitz, WD; Shea, HA; Yang, J | 1 |
| Pedras, MS; Zaharia, IL | 1 |
| Fu, Y; Tang, XC; Zhou, J | 1 |
| Bari, RP; Broekaert, WF; Brouwer, M; Cammue, BP; Eggermont, K; Garmier, M; Penninckx, IA; Thomma, BP; Tierens, KF | 1 |
| Ahiahonu, PW; Pedras, MS | 2 |
| Dabrowska-Iwanicka, A; Giermasz, A; Golab, J; Grzela, T; Hoser, G; Jakóbisiak, M; Jalili, A; Makowski, M; Marczak, M; Olszewska, D | 1 |
| Kutschy, P; Mezencev, R; Mojzis, J; Pilatova, M | 1 |
| Cvitkovic, E; Koeppel, F; Larsen, AK; Poindessous, V; Raymond, E; Waters, SJ | 1 |
| Jeong, IH; Lee, S; Oh, S; Shin, WS | 1 |
| Liu, J; Pedras, MS | 1 |
| Ruszkowska, J; Wróbel, JT | 1 |
| Choi, J; Ji, M; Lee, J; Lee, Y | 1 |
| Hossain, M; Montaut, S; Pedras, MS; Sarwar, MG | 1 |
| Jha, M; Pedras, MS | 1 |
| Calvo, F; Cvitkovic, E; Koeppel, F; Laar, ES; Larsen, AK; Lokiec, F; Poindessous, V; Raymond, E; Serova, M; Waters, SJ | 1 |
| Pedras, MS; Suchy, M | 1 |
| Choi, WS; Han, JW; Kang, JK; Lee, HW; Lee, KR; Shin, SG | 1 |
| Amiar, Z; Bouizgarne, B; Bouteau, F; Brault, M; Briand, J; El Hadrami, I; El-Maarouf-Bouteau, H; Frankart, C; Madiona, K; Monestiez, M; Ouhdouch, Y; Pennarun, AM; Reboutier, D; Rona, JP; Trouverie, J | 1 |
| Ahiahonu, PW; Pedras, MS; Suchy, M | 1 |
| Arihara, S; Tanaka, T; Umeyama, A; Yoshikawa, K | 1 |
| Shi, YP; We, QY; Wu, QX | 1 |
| Okinyo, DP; Pedras, MS | 2 |
| Lee, J; Wu, XH; Zhou, HJ | 1 |
| Martin, SG; Mukherjee, A | 1 |
| Glawischnig, E | 1 |
| Chadwick, J; Cohen, GM; Maggs, JL; Mercer, AE; O'Neill, PM; Park, BK; Sun, XM | 1 |
| Chu, D; Fu, E; Jin, F; Liu, T; Mu, D; Xie, Y; Zhang, W | 1 |
| Cuff, CF; Gardner, K; Huang, L; Kim, JE; Li, QQ; Li, X; Reed, E; Wang, G; Zhao, J; Zou, B | 1 |
| Cao, B; Chen, H; Xie, HG; Zhang, HW; Zou, ZM | 1 |
| Fujiwara, H; Inoue, M; Maruyama, R; Minatoguchi, S; Nagatsu, A; Nakagawa, M; Ohno, T; Okubo, M; Takemura, G; Tanabe, H | 1 |
| Basilico, N; D'Alessandro, S; Gelati, M; Haynes, RK; Parati, EA; Taramelli, D | 1 |
| Batsuren, D; Kang, K; Kim, CY; Lee, HJ; Lee, SB; Nho, CW; Tunsag, J | 1 |
| Adio, AM; Pedras, MS | 1 |
| Bouchaud, O; Izri, A | 1 |
| Brzana, W; Jabłoński, M; Majdan, M; Mitura, A; Parada-Turska, J; Rzeski, W | 1 |
| Chang, YC; Kang, JH; Kim, CH; Kim, T; Min, KS; Park, WH | 1 |
| Chung, IM; Kim, MY; Moon, HI; Park, WH | 1 |
| Fu, JJ; Hu, XJ; Jin, HZ; Qin, JJ; Wang, Y; Yan, SK; Zhang, WD | 1 |
| Ahmed, AF; Chen, SP; Dai, CF; Sheu, JH; Su, JH; Wu, YC; Yeh, HC | 1 |
| Tallman, M | 1 |
| Chumala, PB; Hauck, DW; Islam, MS; Jin, W; Pedras, MS | 1 |
| Dossa, PD; Litz, JP; Morrison, KC; Scherpelz, KP; Vosburg, DA | 1 |
| Kutschy, P; McDonald, JF; Mezencev, R; Salayova, A; Updegrove, T | 1 |
| Docampo, R; Galizzi, M; Kutschy, P; Mezencev, R | 1 |
| Alkhatib, R; Bailleul, F; Biabiany, M; Güzel, Y; Hennebelle, T; Idziorek, T; Joha, S; Preudhomme, C; Quesnel, B; Roumy, V; Sahpaz, S | 1 |
| Pedras, MS; Snitynsky, RB | 1 |
| Bauer, R; Bodensieck, A; Danesch, U; Gaunitz, F; Gebhardt, R | 1 |
| Kong, LY; Kuang, HX; Wang, JS; Wang, QH; Xia, YG; Yang, BY | 1 |
| Hossain, S; Pedras, MS; Snitynsky, RB | 1 |
| Mauch, F; Schlaeppi, K | 1 |
| Chen, Z; Liu, Y; Mao, G; Meng, X; Zhang, S; Zheng, Z | 1 |
| Beets, C; Dubery, I | 1 |
| Cramer, N | 1 |
| Kai, K; Ogata, Y; Ogawa, T; Ohta, D; Saga, H; Sakurai, N; Shibata, D; Suzuki, H | 1 |
| Beets, CA; Dubery, I; Huang, JC; Madala, NE | 1 |
| Bun, SS; Elias, R; Khay, M; Mabrouki, F; Mahiou-Leddet, V; Ollivier, E; Sothea, K; Toeng, P | 1 |
| Chetram, M; Hinton, C; Mezencev, R; Neal, CL; Odero-Marah, VA; Smith, BA; Vo, B | 1 |
| Chen, WD; Deng, R; Feng, GK; Lan, WJ; Li, DD; Li, HJ; Tang, J; Wu, KW; Yang, F; Zhang, H; Zhu, XF | 1 |
| Abdoli, A; Pedras, MS | 1 |
| Hu, J; Li, C; Li, H; Li, L; Mei, X; Ren, F; Weng, Z; Wu, M; Zhang, H; Zhao, Y | 1 |
| Johansson, AS; Leinartaitė, L | 1 |
| Minic, Z; Pedras, MS | 1 |
| Ding, YQ; Huang, JX; Jiang, WH; Lam, CK; Lan, WJ; Li, HJ; Liang, WL; Mo, YF; Qian, XJ; Zhu, XF | 1 |
| Abdoli, A; Minic, Z; Pedras, MS | 1 |
| Li, JJ; Ma, ZY; Yang, GL; Yang, Q; Zhang, YG | 1 |
| Chen, CZ; Galkin, A; Herzberg, O; Kulakova, L; Marugan, JJ; Southall, N; Zheng, W | 1 |
| Glawischnig, E; Hincha, DK; Mucha, S; Müller, TM; Walther, D | 1 |
| Ding, JH; Ding, ZH; Dong, ZJ; Feng, T; Li, ZH; Liu, JK; Wei, K | 1 |
| Klein, AP; Sattely, ES | 1 |
| Pedras, MSC; To, QH | 1 |
| Chang, KO; Kim, Y | 1 |
| Abdoli, A; Pedras, MSC | 1 |
| He, X; He, Y; Meng, X; Wang, X; Wang, Y; Xu, J; Zhang, S; Zhou, J | 1 |
| Choudhary, M; Eichmann, R; Glawischnig, E; Grill, E; Heinzlmeir, S; Hückelhoven, R; Kirchhelle, C; Kowalski, N; Kriechbaumer, V; Kuster, B; Mucha, S; Strickland, B | 1 |
| Bai, LG; Cao, F; Han, C; Jian, MM; Ma, ZY; Xu, Y; Yang, K | 1 |
| A Lobaccaro, JM; Baron, S; Bayala, B; Buñay, J; Figueredo, G; Guenné, S; Mahoukèdè Zohoncon, T; Nadembega, C; Simpore, J; Wendkuuni Djigma, F; Yonli, A | 1 |
| Kanno, Y; Kizu, R; Ozawa, M; Sanada, N; Taga, C; Yamashita, N | 1 |
| Daughenbaugh, KF; Flenniken, ML; Parekh, F | 1 |
| Li, L; Liao, A; Lu, A; Wang, Q; Wang, T; Wang, Z | 1 |
| Cui, Y; Duan, W; Lan, H; Li, D; Li, F; Lin, G; Zhu, X | 1 |
3 review(s) available for thiazoles and sesquiterpenes
| Article | Year |
|---|---|
Total synthesis of marine natural products driven by novel structure, potent biological activity, and/or synthetic methodology.
Topics: Animals; Biological Products; Dinoflagellida; Epoxy Compounds; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Biology; Marine Toxins; Methods; Porifera; Sesquiterpenes; Thiazoles | 2000 |
Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers.
Topics: Animals; Anticarcinogenic Agents; Brassicaceae; Chemoprevention; Disease Models, Animal; Humans; Indoles; Neoplasms, Experimental; Phytoalexins; Plant Extracts; Sesquiterpenes; Spiro Compounds; Terpenes; Thiazoles; Thiocarbamates | 2003 |
Tryptophan-derived sulfur-containing phytoalexins--a general overview.
Topics: Anti-Infective Agents; Indoles; Phytoalexins; Plant Extracts; Plants; Sesquiterpenes; Sulfur; Terpenes; Thiazoles; Thiocarbamates; Tryptophan | 2003 |
96 other study(ies) available for thiazoles and sesquiterpenes
| Article | Year |
|---|---|
Cytotoxic effect of T-2 mycotoxin on cells in culture as determined by a rapid colorimetric bioassay.
Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Colorimetry; Humans; Insecta; Lymphocytes; Rabbits; Rats; Sesquiterpenes; Species Specificity; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1988 |
Role of glutathione in the toxicity of the sesquiterpene lactones hymenoxon and helenalin.
Topics: Acetylcysteine; Animals; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Sesquiterpenes; Sesquiterpenes, Guaiane; Thiazoles; Thiazolidines; Toxins, Biological | 1988 |
Cellular effects of T-2 mycotoxin on two different cell lines.
Topics: Animals; Binding Sites; Cattle; Cell Line; Cells; Chromium Radioisotopes; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Eukaryotic Cells; Female; Mitochondria; Ovary; Protein Synthesis Inhibitors; Sesquiterpenes; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1988 |
Detection of the lethal effects of T-2 mycotoxin on cells using a rapid colorimetric viability assay.
Topics: Animals; Cell Survival; Cells, Cultured; Colorimetry; DNA; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Protein Biosynthesis; Sesquiterpenes; T-2 Toxin; Tetrazolium Salts; Thiazoles | 1987 |
Helenalin: mechanism of toxic action.
Topics: Animals; Drug Interactions; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Pyrrolidonecarboxylic Acid; Sesquiterpenes; Sesquiterpenes, Guaiane; Thiazoles; Thiazolidines; Toxins, Biological | 1986 |
Evaluation of the toxicological risk to humans of caulerpenyne using human hematopoietic progenitors, melanocytes, and keratinocytes in culture.
Topics: Cells, Cultured; Chlorophyta; Chromatography, High Pressure Liquid; Coloring Agents; Dose-Response Relationship, Drug; Eukaryota; Fetal Blood; Hematopoietic Stem Cells; Humans; Keratinocytes; Lethal Dose 50; Marine Toxins; Melanocytes; Neutral Red; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 1996 |
Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haemin.
Topics: Animals; Antimalarials; Artemisinins; Dose-Response Relationship, Drug; Drug Synergism; Hemin; Neurites; Neurons; Rats; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 1997 |
Syringin 4-O-beta-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii.
Topics: Animals; Cell Survival; Coloring Agents; Enzyme Inhibitors; Hydrolysis; Immunosuppressive Agents; Lactose; Macrophages; Magnetic Resonance Spectroscopy; Mice; Nitric Oxide; Nitric Oxide Synthase; Plant Epidermis; Plants, Medicinal; Sesquiterpenes; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 1996 |
Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis.
Topics: Arabidopsis; Caulimovirus; Indoles; Mosaic Viruses; Phytoalexins; Plant Diseases; Plant Extracts; Plant Proteins; Pseudomonas; RNA, Messenger; Sesquiterpenes; Terpenes; Thiazoles; Transcription, Genetic; Tryptophan; Xanthomonas campestris | 1996 |
Structure-cytotoxicity relationships of some helenanolide-type sesquiterpene lactones.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Chromatography, High Pressure Liquid; Computer Simulation; Drug Screening Assays, Antitumor; Lactones; Mice; Models, Structural; Molecular Conformation; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.
Topics: Antineoplastic Agents, Phytogenic; Artemisinins; Cell Cycle; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Cytotoxic activities of hypocretenolides from Leontodon hispidus.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Bone Marrow Cells; Colony-Forming Units Assay; Coloring Agents; Drug Screening Assays, Antitumor; Erythropoiesis; Female; Humans; Male; Plants, Medicinal; Sesquiterpenes; Sesquiterpenes, Guaiane; Stem Cells; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Deficiency in phytoalexin production causes enhanced susceptibility of Arabidopsis thaliana to the fungus Alternaria brassicicola.
Topics: Alternaria; Anti-Infective Agents; Antifungal Agents; Arabidopsis; Botrytis; Cyclopentanes; Defensins; Disease Susceptibility; Ethylenes; Gene Expression Regulation, Plant; Indoles; Mutation; Oxylipins; Phytoalexins; Plant Diseases; Plant Extracts; Plant Growth Regulators; Plant Proteins; Salicylic Acid; Sesquiterpenes; Terpenes; Thiazoles | 1999 |
Positive identification of the puberty-accelerating pheromone of the house mouse: the volatile ligands associating with the major urinary protein.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Female; Ketones; Ligands; Male; Mice; Mice, Inbred ICR; Molecular Structure; Pheromones; Proteins; Recombinant Fusion Proteins; Sesquiterpenes; Sexual Maturation; Thiazoles | 1999 |
Arabidopsis PAD3, a gene required for camalexin biosynthesis, encodes a putative cytochrome P450 monooxygenase.
Topics: Agrobacterium tumefaciens; Amino Acid Sequence; Anti-Bacterial Agents; Arabidopsis; Arabidopsis Proteins; Base Sequence; Cytochrome P-450 Enzyme System; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Immunity, Innate; Indoles; Mixed Function Oxygenases; Molecular Sequence Data; Phytoalexins; Plant Extracts; Plant Leaves; Pseudomonas; Sequence Alignment; Sequence Homology, Amino Acid; Sesquiterpenes; Terpenes; Thiazoles | 1999 |
Biotransformation of the phytoalexin camalexin by the phytopathogen Rhizoctonia solani.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Indoles; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Phytoalexins; Plant Extracts; Rhizoctonia; Sesquiterpenes; Terpenes; Thiazoles; Virulence | 2000 |
Enantiomeric excess of a cruciferous phytoalexin, spirobrassinin, and its enantiomeric enrichment in an achiral HPLC system.
Topics: Brassica; Chromatography, High Pressure Liquid; Phytoalexins; Plant Extracts; Sesquiterpenes; Spectrum Analysis; Spiro Compounds; Stereoisomerism; Terpenes; Thiazoles | 2000 |
Unprecedented Vilsmeier formylation: expedient syntheses of the cruciferous phytoalexins sinalexin and brassilexin and discovery of a new heteroaromatic ring system.
Topics: Ammonia; Anti-Infective Agents; Antifungal Agents; Formates; Indoles; Models, Chemical; Phytoalexins; Plant Extracts; Sesquiterpenes; Terpenes; Thiazoles; Thiones | 2001 |
Huperzine A and donepezil protect rat pheochromocytoma cells against oxygen-glucose deprivation.
Topics: Alkaloids; Alzheimer Disease; Animals; Cell Size; Cell Survival; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Glucose; Hypoxia-Ischemia, Brain; Indans; Lipid Peroxidation; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Piperidines; Rats; Sesquiterpenes; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2001 |
Esa1, an Arabidopsis mutant with enhanced susceptibility to a range of necrotrophic fungal pathogens, shows a distorted induction of defense responses by reactive oxygen generating compounds.
Topics: Alternaria; Arabidopsis; Cyclopentanes; Defensins; Ethylenes; Gene Expression Regulation, Plant; Immunity, Innate; Indoles; Mutation; Nitrobenzoates; Oxylipins; Paraquat; Phytoalexins; Plant Diseases; Plant Extracts; Plant Proteins; Reactive Oxygen Species; Salicylates; Sesquiterpenes; Terpenes; Thiazoles | 2002 |
Probing the phytopathogenic stem rot fungus with phytoalexins and analogues: unprecedented glucosylation of camalexin and 6-methoxycamalexin.
Topics: Anti-Infective Agents; Ascomycota; Biotransformation; Glucose; Glycosylation; Inactivation, Metabolic; Indoles; Molecular Probes; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phytoalexins; Plant Extracts; Sesquiterpenes; Terpenes; Thiazoles | 2002 |
Augmented antitumour effects of combination therapy with TNP-470 and chemoimmunotherapy in mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzothiazoles; Blotting, Western; Cell Division; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexanes; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Immunotherapy; Interferon-gamma; Interleukin-12; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2002 |
Enhanced antitumor activity of irofulven in combination with 5-fluorouracil and cisplatin in human colon and ovarian carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Inhibitory Concentration 50; Models, Chemical; Ovarian Neoplasms; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2003 |
Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells.
Topics: Acetals; Artemisinins; Cell Division; Colorimetry; Endothelial Cells; Female; Humans; Lactones; Pregnancy; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Umbilical Veins | 2003 |
Designer phytoalexins: probing camalexin detoxification pathways in the phytopathogen Rhizoctonia solani.
Topics: Biological Assay; Biotransformation; Inactivation, Metabolic; Indoles; Molecular Structure; Phytoalexins; Plant Extracts; Rhizoctonia; Sesquiterpenes; Terpenes; Thiazoles; Time Factors | 2004 |
Induction of apoptosis by ar-turmerone on various cell lines.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; K562 Cells; Ketones; Models, Chemical; Plant Extracts; Rats; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Time Factors; Toluene; U937 Cells | 2004 |
Determination of the enantiomeric purity of the phytoalexins spirobrassinins by 1H NMR using chiral solvation.
Topics: Magnetic Resonance Spectroscopy; Molecular Conformation; Phytoalexins; Plant Extracts; Sesquiterpenes; Solvents; Spiro Compounds; Stereoisomerism; Terpenes; Thiazoles | 2004 |
Phytotoxin production and phytoalexin elicitation by the phytopathogenic fungus Sclerotinia sclerotiorum.
Topics: Animals; Artemia; Ascomycota; Biological Assay; Biomarkers; Brassicaceae; Drug Resistance; Indoles; Larva; Oleic Acid; Phytoalexins; Plant Extracts; Plant Leaves; Sesquiterpenes; Species Specificity; Spiro Compounds; Terpenes; Thiazoles | 2004 |
Concise syntheses of the cruciferous phytoalexins brassilexin, sinalexin, wasalexins, and analogues: expanding the scope of the vilsmeier formylation.
Topics: Antifungal Agents; Formates; Indoles; Microbial Sensitivity Tests; Mitosporic Fungi; Molecular Structure; Oxidation-Reduction; Phytoalexins; Plant Extracts; Sesquiterpenes; Terpenes; Thiazoles | 2005 |
Characterizations of irofulven cytotoxicity in combination with cisplatin and oxaliplatin in human colon, breast, and ovarian cancer cells.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Genes, p53; HT29 Cells; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2006 |
Design, synthesis, and antifungal activity of inhibitors of brassilexin detoxification in the plant pathogenic fungus Leptosphaeria maculans.
Topics: Antifungal Agents; Ascomycota; Biological Assay; Biotransformation; Drug Design; Drug Evaluation, Preclinical; Indoles; Kinetics; Molecular Structure; Phytoalexins; Plant Extracts; Plants; Sesquiterpenes; Terpenes; Thiazoles | 2006 |
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitochondria; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane; Tetrazolium Salts; Thiazoles | 2005 |
Early physiological responses of Arabidopsis thaliana cells to fusaric acid: toxic and signalling effects.
Topics: Arabidopsis; Arabidopsis Proteins; Calcium; Cells, Cultured; Fusaric Acid; Hydrogen-Ion Concentration; Indoles; Membrane Potentials; Oxygen; Patch-Clamp Techniques; Phytoalexins; Plant Extracts; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Terpenes; Thiazoles | 2006 |
Unprecedented chemical structure and biomimetic synthesis of erucalexin, a phytoalexin from the wild crucifer Erucastrum gallicum.
Topics: Antifungal Agents; Ascomycota; Biomimetics; Brassicaceae; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Phytoalexins; Plant Extracts; Rhizoctonia; Sesquiterpenes; Spiro Compounds; Terpenes; Thiazoles | 2006 |
Three abietane diterpenes and two diterpenes incorporated sesquiterpenes from the bark of Cryptomeria japonica.
Topics: Abietanes; Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cryptomeria; Drug Screening Assays, Antitumor; Escherichia coli; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Plant Bark; Sesquiterpenes; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Tetrazolium Salts; Thiazoles | 2006 |
Sesquiterpenes with various carbon skeletons from Ligularia virgaurea spp. oligocephala.
Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Cell Line, Tumor; Etoposide; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2006 |
En route to erucalexin: a unique rearrangement in the crucifer phytoalexin biosynthetic pathway.
Topics: Brassicaceae; Indoles; Molecular Structure; Phytoalexins; Plant Leaves; Sesquiterpenes; Spiro Compounds; Terpenes; Thiazoles | 2006 |
Dihydroartemisinin inhibits angiogenesis induced by multiple myeloma RPMI8226 cells under hypoxic conditions via downregulation of vascular endothelial growth factor expression and suppression of vascular endothelial growth factor secretion.
Topics: Allantoin; Angiogenesis Inhibitors; Animals; Artemisinins; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Culture Media, Conditioned; Down-Regulation; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Hypoxia; Membranes; Multiple Myeloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2006 |
In vitro cytotoxicity of Phortress against colorectal cancer.
Topics: Biological Assay; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclohexanes; Endothelial Cells; Fatty Acids, Unsaturated; Fibroblasts; Humans; Neovascularization, Physiologic; Paclitaxel; Prodrugs; Sesquiterpenes; Thiazoles | 2006 |
The role of cytochrome P450 enzymes in the biosynthesis of camalexin.
Topics: Arabidopsis; Cytochrome P-450 Enzyme System; Indoles; Kinetics; Phytoalexins; Sesquiterpenes; Terpenes; Thiazoles; Tryptophan | 2006 |
Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds.
Topics: Antimalarials; Apoptosis; Artemisia; Artemisinins; Drugs, Chinese Herbal; Free Radicals; HL-60 Cells; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2007 |
The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.
Topics: Antimalarials; Apoptosis; Artemisinins; Blotting, Western; Calcium; Cell Line, Tumor; Chelating Agents; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; Humans; Imidazoles; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Pyridines; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2008 |
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Line, Tumor; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lung Neoplasms; Medicine, Chinese Traditional; Mutation; Sesquiterpenes; Taxoids; Tetrazolium Salts; Thiazoles | 2007 |
Cytotoxic germacranolide sesquiterpene from Inula cappa.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Ethanol; HeLa Cells; Humans; Inula; K562 Cells; KB Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Sesquiterpenes; Sesquiterpenes, Germacrane; Solvents; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles | 2007 |
Sesquiterpene lactone suppresses vascular smooth muscle cell proliferation and migration via inhibition of cell cycle progression.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Chemotaxis; Cyclin D1; Depression, Chemical; G1 Phase; Indicators and Reagents; Lactones; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2007 |
Differential effects on angiogenesis of two antimalarial compounds, dihydroartemisinin and artemisone: implications for embryotoxicity.
Topics: Adult; Animals; Antimalarials; Aorta, Thoracic; Artemisinins; Capillaries; Cell Line; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Embryo, Mammalian; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Humans; Male; Neovascularization, Physiologic; Neural Tube; Pregnancy; Rats; Rats, Inbred F344; Sesquiterpenes; Teratogens; Tetrazolium Salts; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatin; DNA, Neoplasm; Enzyme Induction; Ethanol; Flow Cytometry; Furans; Humans; Lactones; Lignans; Metabolic Detoxication, Phase II; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Plant Extracts; Saussurea; Sesquiterpenes; Solvents; Tetrazolium Salts; Thiazoles | 2007 |
Remarkable incorporation of the first sulfur containing indole derivative: another piece in the biosynthetic puzzle of crucifer phytoalexins.
Topics: Brassica napus; Glucosinolates; Hydroxamic Acids; Indoles; Phytoalexins; Plant Extracts; Plant Tubers; Sesquiterpenes; Spiro Compounds; Sulfur; Terpenes; Thiazoles | 2008 |
Phytoalexins and phytoanticipins from the wild crucifers Thellungiella halophila and Arabidopsis thaliana: rapalexin A, wasalexins and camalexin.
Topics: Arabidopsis; Brassicaceae; Genome, Plant; Indoles; Isothiocyanates; Molecular Structure; Phytoalexins; Sesquiterpenes; Sulfides; Terpenes; Thiazoles | 2008 |
[New antiparasitic drugs].
Topics: Albendazole; Antimalarials; Antiparasitic Agents; Benzimidazoles; Cyclohexanes; Fatty Acids, Unsaturated; Humans; Ivermectin; Nitro Compounds; Phosphorylcholine; Praziquantel; Sesquiterpenes; Thiazoles; Triclabendazole | 2008 |
Parthenolide inhibits proliferation of fibroblast-like synoviocytes in vitro.
Topics: Animals; Arthritis, Rheumatoid; Bromodeoxyuridine; Cell Line; Cell Proliferation; Fibroblasts; Humans; Hyperplasia; Phytotherapy; Rabbits; Sesquiterpenes; Synovial Membrane; Tanacetum parthenium; Tetrazolium Salts; Thiazoles | 2008 |
Proteome profiling of U2OS cell line in response to a prenylphenol antibiotic isolated from a phytopathogenic fungus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Ascomycota; Blotting, Western; Cell Line; Cell Line, Tumor; Databases, Protein; Electrophoresis, Gel, Two-Dimensional; Gelatin; Humans; Hydrolysis; Image Processing, Computer-Assisted; Indicators and Reagents; Molecular Sequence Data; Proteome; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Trypsin | 2008 |
Histone deacetylase inhibitors from the rhizomes of Zingiber zerumbet.
Topics: Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Magnetic Resonance Spectroscopy; Plant Roots; Sesquiterpenes; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Zingiber officinale | 2008 |
Japonicones A-D, bioactive dimeric sesquiterpenes from Inula japonica Thunb.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Crystallography, X-Ray; Dimerization; Humans; Inula; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Molecular Structure; Neoplasms; Plant Extracts; Sesquiterpenes; Sesquiterpenes, Eudesmane; Sesquiterpenes, Guaiane; Stereoisomerism; Tetrazolium Salts; Thiazoles | 2009 |
Novel norhumulene and xeniaphyllane-derived terpenoids from a formosan soft coral Sinularia gibberosa.
Topics: Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Diterpenes; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Monocyclic Sesquiterpenes; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Taiwan; Terpenes; Tetrazolium Salts; Thiazoles | 2009 |
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin | 2008 |
The phytopathogenic fungus Alternaria brassicicola: phytotoxin production and phytoalexin elicitation.
Topics: Alternaria; Antifungal Agents; Brassica napus; Diterpenes; Gene Expression Regulation, Plant; Magnetic Resonance Spectroscopy; Molecular Structure; Mustard Plant; Phytoalexins; Plant Leaves; Sesquiterpenes; Spiro Compounds; Terpenes; Thiazoles | 2009 |
A concise, biomimetic total synthesis of (+)-davanone.
Topics: Antifungal Agents; Artemisia; Biological Products; Catalysis; Cyclization; Esterification; Molecular Structure; Oxidation-Reduction; Palladium; Parasympatholytics; Sesquiterpenes; Stereoisomerism; Thiazoles | 2009 |
The design, synthesis and anticancer activity of new nitrogen mustard derivatives of natural indole phytoalexin 1-methoxyspirobrassinol.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Differentiation; Cell Proliferation; DNA Damage; Drug Design; Drug Screening Assays, Antitumor; Female; Glutathione; Humans; Indoles; Inhibitory Concentration 50; Melphalan; Molecular Structure; Phytoalexins; Sesquiterpenes; Structure-Activity Relationship; Terpenes; Thiazoles; Tumor Cells, Cultured | 2009 |
Trypanosoma cruzi: antiproliferative effect of indole phytoalexins on intracellular amastigotes in vitro.
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Indoles; Inhibitory Concentration 50; Myoblasts; Phytoalexins; Rats; Sesquiterpenes; Spiro Compounds; Structure-Activity Relationship; Terpenes; Thiazoles; Thiocarbamates; Trypanosoma cruzi | 2009 |
Humulane and germacrane sesquiterpenes from Ferula lycia.
Topics: Bone Marrow Cells; Dasatinib; Drug Screening Assays, Antitumor; Ferula; Humans; K562 Cells; Molecular Structure; Protein-Tyrosine Kinases; Pyrimidines; Sesquiterpenes; Sesquiterpenes, Germacrane; Thiazoles; Turkey | 2010 |
Impact of cruciferous phytoalexins on the detoxification of brassilexin by the blackleg fungus pathogenic to brown mustard.
Topics: Ascomycota; Indoles; Molecular Structure; Mustard Plant; Phytoalexins; Sesquiterpenes; Thiazoles | 2010 |
Differential and stereoselective in vitro cytotoxicity of eremophilane sesquiterpenes of Petasites hybridus rhizomes in rat hepatocytes.
Topics: Animals; Cell Membrane; Cell Respiration; Cytotoxins; Energy Metabolism; Hepatocytes; Naphthalenes; Petasites; Polycyclic Sesquiterpenes; Rats; Rhizome; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2011 |
Sesquiterpenes from Chloranthus japonicus.
Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Humans; Magnoliopsida; Molecular Structure; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2011 |
Detoxification of cruciferous phytoalexins in Botrytis cinerea: spontaneous dimerization of a camalexin metabolite.
Topics: Antifungal Agents; Botrytis; Brassicaceae; Inactivation, Metabolic; Indoles; Molecular Structure; Phytoalexins; Sesquiterpenes; Thiadiazoles; Thiazoles; Thiocarbamates | 2011 |
Indolic secondary metabolites protect Arabidopsis from the oomycete pathogen Phytophthora brassicae.
Topics: Arabidopsis; Arabidopsis Proteins; Disease Resistance; Glucosinolates; Indoles; Mutation; Phytoalexins; Phytophthora; Plant Diseases; Sesquiterpenes; Thiazoles | 2010 |
Phosphorylation of a WRKY transcription factor by two pathogen-responsive MAPKs drives phytoalexin biosynthesis in Arabidopsis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Botrytis; DNA, Plant; Gene Expression Regulation, Plant; Indoles; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; Phosphorylation; Phytoalexins; Plants, Genetically Modified; Promoter Regions, Genetic; Protein Binding; Seedlings; Sesquiterpenes; Thiazoles; Transcription Factors; Transcription, Genetic | 2011 |
Quantification of camalexin, a phytoalexin from Arabidopsis thaliana: a comparison of five analytical methods.
Topics: Arabidopsis; Biochemistry; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Flame Ionization; Indoles; Mass Spectrometry; Phytoalexins; Reference Standards; Sesquiterpenes; Spectrometry, Fluorescence; Thiazoles | 2011 |
Catalytic asymmetric functionalization of inert bonds and synthesis of bioactive natural products.
Topics: Biological Products; Catalysis; Depsipeptides; Hydrogen Bonding; Molecular Structure; Sesquiterpenes; Stereoisomerism; Thiazoles | 2011 |
Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis.
Topics: Alternaria; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cellular Senescence; Gene Expression Regulation, Plant; Genes, Reporter; Green Fluorescent Proteins; Indoles; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Phytoalexins; Plant Diseases; Plant Leaves; Plant Roots; Recombinant Fusion Proteins; Sequence Alignment; Sesquiterpenes; Signal Transduction; Thiazoles; Transcription Factors; Transcriptome | 2012 |
Activation of camalexin biosynthesis in Arabidopsis thaliana in response to perception of bacterial lipopolysaccharides: a gene-to-metabolite study.
Topics: Arabidopsis; Burkholderia cepacia; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Plant; Genes, Plant; Host-Pathogen Interactions; Indoles; Lipopolysaccharides; Metabolome; Phytoalexins; Plant Diseases; Principal Component Analysis; Sesquiterpenes; Thiazoles; Transcription, Genetic; Transcriptional Activation; Tryptophan; Tryptophan Synthase; Up-Regulation | 2012 |
HPLC analysis and cytotoxic activity of Vernonia cinerea.
Topics: Antineoplastic Agents, Phytogenic; Cambodia; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methanol; Methylene Chloride; Sesquiterpenes; Solvents; Tetrazolium Salts; Thiazoles; Vernonia; Water | 2012 |
The phytoalexin camalexin mediates cytotoxicity towards aggressive prostate cancer cells via reactive oxygen species.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Humans; Indoles; Male; Neoplasm Invasiveness; Oxidative Stress; Phytoalexins; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; Sesquiterpenes; Snail Family Transcription Factors; Thiazoles; Time Factors; Transcription Factors; Transfection | 2013 |
Hirsutanol A, a novel sesquiterpene compound from fungus Chondrostereum sp., induces apoptosis and inhibits tumor growth through mitochondrial-independent ROS production: hirsutanol A inhibits tumor growth through ROS production.
Topics: Agaricales; Animals; Apoptosis; Cell Death; Cell Line, Tumor; Cytochromes c; Cytosol; Flow Cytometry; Humans; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasm Transplantation; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Tetrazolium Salts; Thiazoles | 2013 |
Metabolism of the phytoalexins camalexins, their bioisosteres and analogues in the plant pathogenic fungus Alternaria brassicicola.
Topics: Alternaria; Antifungal Agents; Biotransformation; Indoles; Models, Molecular; Phytoalexins; Sesquiterpenes; Thiazoles | 2013 |
Isoalantolactone inhibits UM-SCC-10A cell growth via cell cycle arrest and apoptosis induction.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin D; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; Head and Neck Neoplasms; Humans; Mitochondria; rho GTP-Binding Proteins; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53 | 2013 |
Disulfide scrambling in superoxide dismutase 1 reduces its cytotoxic effect in cultured cells and promotes protein aggregation.
Topics: Acetamides; Apoenzymes; Benzothiazoles; Cell Line, Tumor; Cell Survival; Cysteine; Cytotoxins; Disulfides; Enzyme Stability; Humans; Protein Multimerization; Protein Structure, Quaternary; Sesquiterpenes; Solubility; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles | 2013 |
The phytoalexins brassilexin and camalexin inhibit cyclobrassinin hydrolase, a unique enzyme from the fungal pathogen Alternaria brassicicola.
Topics: Alternaria; Fungal Proteins; Indoles; Phytoalexins; Sesquiterpenes; Spores, Fungal; Thiazoles; Thiocarbamates | 2014 |
Induced marine fungus Chondrostereum sp. as a means of producing new sesquiterpenoids chondrosterins I and J by using glycerol as the carbon source.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Circular Dichroism; Crystallography, X-Ray; Culture Media; Drug Screening Assays, Antitumor; Glycerol; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Polyporaceae; Sesquiterpenes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2014 |
The phytoalexin camalexin induces fundamental changes in the proteome of Alternaria brassicicola different from those caused by brassinin.
Topics: Alternaria; Anti-Infective Agents; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Fungal Proteins; Hyphae; Indoles; Mass Spectrometry; Phytoalexins; Proteome; Sesquiterpenes; Spores, Fungal; Thiazoles; Thiocarbamates | 2014 |
[Design, synthesis and evaluation of N-acyl-4-phenylthiazole-2-amines as acetylcholinesterase inhibitors].
Topics: Acetylcholinesterase; Alkaloids; Amines; Cholinesterase Inhibitors; Drug Design; Rivastigmine; Sesquiterpenes; Structure-Activity Relationship; Thiazoles | 2014 |
Discovery of novel antigiardiasis drug candidates.
Topics: Aminopeptidases; Animals; Antiprotozoal Agents; Axenic Culture; Carbadox; Cyclohexanes; Drug Discovery; Drug Resistance; Fatty Acids, Unsaturated; Giardia lamblia; Giardiasis; Glycoproteins; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Methionyl Aminopeptidases; Metronidazole; Mice; Parasitic Sensitivity Tests; Sesquiterpenes; Species Specificity; Structure-Activity Relationship; Thiazoles; Trophozoites | 2014 |
Substantial reprogramming of the Eutrema salsugineum (Thellungiella salsuginea) transcriptome in response to UV and silver nitrate challenge.
Topics: Biosynthetic Pathways; Brassicaceae; Cellular Reprogramming; Gene Expression Regulation, Plant; Gene Knockout Techniques; Glucosinolates; Indoles; Metals, Heavy; Phytoalexins; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Silver Nitrate; Stress, Physiological; Thiazoles; Transcription Factors; Transcription, Genetic; Transcriptome; Tryptophan; Ultraviolet Rays | 2015 |
Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Antineoplastic Agents; Basidiomycota; Drug Screening Assays, Antitumor; Female; Humans; Isoenzymes; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2016 |
Two cytochromes P450 catalyze S-heterocyclizations in cabbage phytoalexin biosynthesis.
Topics: Base Sequence; Biocatalysis; Brassica rapa; Brassicaceae; Cyclization; Cytochrome P-450 Enzyme System; Escherichia coli; Gene Expression; High-Throughput Nucleotide Sequencing; Indoles; Isoenzymes; Kinetics; Microsomes; Molecular Sequence Data; Phytoalexins; Plant Leaves; Plant Proteins; Recombinant Proteins; RNA, Messenger; Sesquiterpenes; Spiro Compounds; Thiazoles; Thiocarbamates; Vegetables | 2015 |
Defense and signalling metabolites of the crucifer Erucastrum canariense: Synchronized abiotic induction of phytoalexins and galacto-oxylipins.
Topics: Antifungal Agents; Brassicaceae; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Indoles; Molecular Structure; Nasturtium; Nuclear Magnetic Resonance, Biomolecular; Oxylipins; Phytoalexins; Plant Leaves; Sesquiterpenes; Spain; Spiro Compounds; Thiazoles; Time Factors | 2017 |
Protein disulfide isomerases as potential therapeutic targets for influenza A and B viruses.
Topics: A549 Cells; Animals; Antiviral Agents; Catechin; Dogs; Drug Discovery; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Influenza A virus; Influenza B virus; Isoenzymes; Madin Darby Canine Kidney Cells; Nitro Compounds; Parabens; Protein Disulfide-Isomerases; Quercetin; RNA, Small Interfering; RNA, Viral; Sesquiterpenes; Thiazoles | 2018 |
Methoxycamalexins and related compounds: Syntheses, antifungal activity and inhibition of brassinin oxidase.
Topics: Antifungal Agents; Ascomycota; Indoles; Oxidoreductases; Phytoalexins; Sesquiterpenes; Structure-Activity Relationship; Thiazoles | 2018 |
The Arabidopsis Pleiotropic Drug Resistance Transporters PEN3 and PDR12 Mediate Camalexin Secretion for Resistance to
Topics: Arabidopsis; Arabidopsis Proteins; ATP-Binding Cassette Transporters; Botrytis; Drug Resistance; Gene Expression Regulation, Plant; Indoles; Membrane Transport Proteins; Mitogen-Activated Protein Kinases; Phytoalexins; Plant Diseases; Plant Immunity; Sesquiterpenes; Thiazoles; Transcription Factors | 2019 |
The Formation of a Camalexin Biosynthetic Metabolon.
Topics: Arabidopsis; Arabidopsis Proteins; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Gene Knockout Techniques; Glutathione Transferase; Indoles; Nicotiana; Phytoalexins; Plant Leaves; Plants, Genetically Modified; Sesquiterpenes; Thiazoles | 2019 |
Design, synthesis and evaluation of new 4-arylthiazole-2-amine derivatives as acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alkaloids; Amines; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Molecular Docking Simulation; Neuroprotective Agents; Rivastigmine; Sesquiterpenes; Structure-Activity Relationship; Thiazoles | 2020 |
Chemical Composition, Antioxidant and Cytotoxic Activities of
Topics: Antioxidants; Burkina Faso; Cations; Cell Line, Tumor; Female; Flow Cytometry; Free Radicals; Gas Chromatography-Mass Spectrometry; HeLa Cells; Humans; Hyptis; In Vitro Techniques; Inhibitory Concentration 50; Male; Monoterpenes; Oils, Volatile; Plant Extracts; Prostatic Neoplasms; Sesquiterpenes; Tetrazolium Salts; Thiazoles; Uterine Cervical Neoplasms | 2020 |
Camalexin, an indole phytoalexin, inhibits cell proliferation, migration, and mammosphere formation in breast cancer cells via the aryl hydrocarbon receptor.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indoles; Phytoalexins; Receptors, Aryl Hydrocarbon; Sesquiterpenes; Thiazoles | 2022 |
Chemical Stimulants and Stressors Impact the Outcome of Virus Infection and Immune Gene Expression in Honey Bees (
Topics: Animals; Bees; Cyclohexanes; Fatty Acids, Unsaturated; Gene Expression; Guanidines; Neonicotinoids; Pesticides; Plant Oils; Sesquiterpenes; Thiazoles; Thymol; Thymus Plant; Virus Diseases | 2021 |
Discovery of Phytoalexin Camalexin and Its Derivatives as Novel Antiviral and Antiphytopathogenic-Fungus Agents.
Topics: Antiviral Agents; Drug Design; Fungi; Indoles; Molecular Docking Simulation; Phytoalexins; Sesquiterpenes; Structure-Activity Relationship; Thiazoles; Tobacco Mosaic Virus | 2022 |
Synthesis, Antiproliferative Evaluation, and Molecular Docking Study of Novel Longifolene-Derived Tetraline Fused Thiazole-Amide Derivatives.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Sesquiterpenes; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazoles | 2023 |