thiazoles has been researched along with serine in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (19.70) | 18.7374 |
| 1990's | 2 (3.03) | 18.2507 |
| 2000's | 28 (42.42) | 29.6817 |
| 2010's | 20 (30.30) | 24.3611 |
| 2020's | 3 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Deutsch, HF; Fett, JW | 1 |
| Guyer, RL; Lovins, RE; Schnute, WC; Todd, CW | 1 |
| Anderson, PJ; Gibson, D | 1 |
| Cooper, AJ; Meister, A | 1 |
| Iwashima, A; Kawasaki, T; Nakamura, M; Nose, Y | 1 |
| Nakamura, M; Nakata, T; Nose, Y | 1 |
| Feingold, DS; Vance, DE | 1 |
| Fairwell, T; Lovins, RE | 1 |
| Linnett, PE; Walker, J | 2 |
| Ashe, BM; Frankshun, R; Jones, H; Morman, H; Mulvey, D; Zimmerman, M | 1 |
| Iinuma, H; Naganawa, H; Shimanaka, K; Takahashi, Y; Takeuchi, T | 1 |
| Bretscher, A; Cao, TT; Deacon, HW; Reczek, D; von Zastrow, M | 1 |
| Miller, DA; Walsh, CT | 1 |
| Golbik, R; Hübner, G; Jordan, F; Seliger, B; Spinka, M; Tittmann, K; Wang, J | 1 |
| Broussard, SR; Dantzer, R; Freund, GG; Johnson, RW; Kelley, KW; Strle, K; Venters, HD; Zhou, JH | 1 |
| McKeown-Longo, PJ; Zheng, M | 1 |
| Alcaraz, L; Hughes, RA; Moody, CJ; Thompson, SP | 1 |
| Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G | 1 |
| Anderson, KC; Chauhan, D; Hideshima, T; Kharbanda, S; Li, G; Mitsiades, C; Mitsiades, N; Munshi, N; Podar, K | 1 |
| Beneytout, JL; Delage, C; Duval, R; Harmand, PO; Jayat-Vignoles, C; Liagre, B; Simon, A | 1 |
| KRAKOFF, IH | 1 |
| LEVY, AL; LI, SO | 1 |
| Furuichi, K; Hagiwara, M; Hosoya, T; Kimura, H; Koizumi, J; Koizumi, T; Krainer, AR; Muraki, M; Murray, MV; Ohkawara, B; Onogi, H; Shibuya, H; Sumi, K; Suzuki, M; Yomoda, J | 1 |
| Hu, H; Jiang, C; Lü, J; Malewicz, B; Wang, Z | 1 |
| Behl, C; Conrad, S; Goodenough, S; Skutella, T | 1 |
| Chan, HH; Chan, LN; Chang, DC; Han, Y; Lee, NT; Li, M; Li, W; Pi, R; Pu, Y; Sucher, NJ | 1 |
| Sebti, SM; Wang, DA | 1 |
| Behl, C; Goodenough, S; Pietrzik, C; Schleusner, D; Skutella, T | 1 |
| Ishihara, K; Kondo, R; Sakakura, A | 1 |
| Bister, B; Hantke, K; Reissbrodt, R; Valdebenito, M; Winkelmann, G | 1 |
| Höfner, G; Kragler, A; Wanner, KT | 1 |
| Berg, M; de la Nava, EM; Dodge, JA; Evers, B; Hankotius, D; Hary, U; Jungheim, LN; Mest, HJ; Mohr, M; Muehl, BS; Petersen, S; Riedel-Herold, G; Ruehter, G; Sommer, B; Tebbe, MJ; Thrasher, KJ; Voelkers, S | 1 |
| Kelleher, NL; Liu, F; Mazur, MT; McLoughlin, SM; Miller, LM; Walsh, CT; Yin, J | 1 |
| Chan, SL; Chan, SS; Fiscus, RR; Fraser, M; Tsang, BK | 1 |
| Friedman, AB; Li, X; Rosborough, KM; Roth, KA; Zhu, W | 1 |
| Biron, E; Chatterjee, J; Kessler, H | 1 |
| Ambron, RT; Schacher, S; Sung, YJ; Wu, F | 1 |
| Hoshiko, S; Iida, M; Kitagawa, H; Osaki, Y; Ozawa, T; Saito, J; Takahata, S; Yoshida, T | 1 |
| Duka, T; Sidhu, A | 1 |
| Blot, B; Sadoul, R; Strappazzon, F; Torch, S; Trioulier, Y; Verna, JM | 1 |
| Buscemi, G; Carlessi, L; Delia, D; Hong, Z; Larson, G; Wu, JZ | 1 |
| Bauchwitz, RP; Chen, S; Jope, RS; Min, WW; Sikorski, C; Yan, Q; Yuskaitis, CJ | 1 |
| Krämer, A; Kreis, NN; Rödel, F; Sanhaji, M; Sommer, K; Strebhardt, K; Yuan, J | 1 |
| Ding, Y; Duan, L; Guo, H; Lei, C; Liao, R; Liu, W; Shen, B; Yu, Y; Zhang, Q | 1 |
| Andrews, G; Bernstein, M; Connolly, S; Hartopp, P; Jackson, CG; Lewis, R; Martin, I; Mete, A; Murray, D; Riley, R; Robinson, DH; Smith, GM; Wells, E; Withnall, WJ | 1 |
| Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W | 1 |
| Kay, EP; Lee, JG; Smith, RE; Song, JS | 1 |
| Ebisui, E; Hirase, H; Hisatsune, C; Mikoshiba, K; Mishima, T; Nagai, T; Takata, N | 1 |
| Asa, SL; Ezzat, S; Mayr, T; Tateno, T; Ullrich, A; Zheng, L | 1 |
| Biagioni, F; Fabrizi, C; Fornai, F; Fumagalli, L; Lenzi, P; Pompili, E; Somma, F | 1 |
| d'Uscio, LV; Das, P; He, T; Katusic, ZS; Santhanam, AV; Younkin, SG | 1 |
| Kim, SJ; McAlpine, SR | 1 |
| Chen, Y; Liu, N; Liu, W; Ma, M; Wang, S; Xue, Y | 1 |
| Bent, AF; Botting, CH; Fuszard, MA; Houssen, WE; Jaspars, M; Koehnke, J; Morawitz, F; Naismith, JH; Shirran, SL; Smellie, IA; Smith, MC | 1 |
| Cai, X; Li, H; Li, L; Li, Y; Liu, Q; Shen, Y; Shi, H; Ye, L; Zhang, X; Zhang, Y; Zhao, Y | 1 |
| Lin, CC; McAlpine, SR; Tantisantisom, W | 1 |
| Cheng, HH; Liao, CK; Wang, SD; Wang, SM; Yeih, DF | 1 |
| Gao, M; Maixner, DW; Weng, HR | 1 |
| Banerjee, S; Clayton, GM; Garavito, RM; Ghebreselasie, K; Hermanson, DJ; Marnett, LJ; Xu, S | 1 |
| LeBlanc, AC; Rouget, R; Sharma, G | 1 |
| Gui, Y; Li, L; Shi, Z; Singh, P; Walsh, MP; Yin, H; Yu, YN; Zheng, XL; Zhou, YX | 1 |
| Cerbón, MA; González-Sánchez, I; Gutiérrez-Nájera, NA; Lira-Rocha, A; Páez-Franco, JC; Rodríguez-Sotres, R; Valencia-Turcotte, LG | 1 |
| Chang, MS; Choi, D; Jang, J; Jung, D; Kang, S; Kim, D; Kim, Y; Lee, Y; Nam, SH; Park, JU; Sim, C | 1 |
| Gao, HY; Li, Y; Li, YT; Liu, MJ; Liu, P; Zhang, ZS; Zhao, SJ | 1 |
| Almilaibary, A | 1 |
66 other study(ies) available for thiazoles and serine
| Article | Year |
|---|---|
The variability of human lambda-chain constant regions and some relationships to V-regions sequences.
Topics: Alanine; Amino Acid Sequence; Chromatography, Gel; Chromatography, Ion Exchange; Cystine; Electrophoresis, Paper; Glutamates; Glycine; Humans; Immunoglobulin lambda-Chains; Immunoglobulin Light Chains; Isoleucine; Leucine; Peptides; Proline; Serine; Thiazoles; Threonine; Valine | 1976 |
The removal of contaminating quadrol by boric acid extraction prior to mass spectralanalysis of amino acid thiazolinones.
Topics: Amino Acids; Aniline Compounds; Boric Acids; Ethylenediamines; Lysine; Mass Spectrometry; Methods; Phenylalanine; Serine; Thiazoles; Threonine | 1975 |
Carboxyl group modification and amide assignments in automated sequencing of proteins.
Topics: Amino Acid Sequence; Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Esters; Glutamates; Glutamine; Glycine; Hydrolysis; Imines; Methanol; Methods; Methylamines; Ribonucleases; Serine; Thiazoles | 1972 |
Action of liver glutamine transaminase and L-amino acid oxidase on several glutamine analogs. Preparation and properties of the 4-S, O, and NH analogs of alpha-ketoglutaramic acid.
Topics: Amidohydrolases; Amino Acid Oxidoreductases; Amino Acids, Diamino; Animals; Carbamates; Carboxylic Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Glutamine; Glyoxylates; Hydrogen Peroxide; Imidazoles; Lactams; Liver; Propionates; Rats; Semicarbazides; Serine; Snakes; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiazoles; Transaminases; Urea; Venoms | 1973 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Effect of aliphatic amino acids and citric acid cycle compounds on early thiamine production by thiazoleless mutant of Escherichia coli.
Topics: Alanine; Amino Acids; Ammonium Chloride; Aspartic Acid; Carbon Isotopes; Culture Media; Dicarboxylic Acids; Escherichia coli; Formates; Fumarates; Glucose; Glutamates; Lysine; Malates; Mutation; Pyruvates; Serine; Succinates; Thiamine; Thiazoles; Valine | 1968 |
Additive Edman degradation to sequence small peptides.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Chromatography, Gas; Hydantoins; Methods; Peptides; Phenylalanine; Serine; Silicones; Thiazoles; Valine | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Biosynthesis of thiamine. Incorporation experiments with 14C-labelled substrates and with (15N)glycine in Saccharomyces cerevisiae.
Topics: Acetates; Carbon Isotopes; Formates; Glycine; Methionine; Nitrogen; Pyrimidines; Radioisotopes; Saccharomyces; Serine; Thiamine; Thiazoles | 1968 |
Biosynthesis of thiamin. IV. C-2 of glycine as the precursor of C-2 of the thiazole moiety in yeast.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Formaldehyde; Formates; Glycine; Methionine; Models, Biological; Saccharomyces; Serine; Sulfonic Acids; Thiamine; Thiazoles | 1969 |
Inhibition of elastase and other serine proteases by heterocyclic acylating agents.
Topics: Animals; Binding Sites; Cathepsins; Chymotrypsin; Humans; Kinetics; Leukocytes; Pancreas; Pancreatic Elastase; Protease Inhibitors; Protein Binding; Saccharin; Serine; Structure-Activity Relationship; Swine; Thiazoles; Trypsin Inhibitors | 1980 |
Novel antibiotics, amythiamicins. III. Structure elucidations of amythiamicins A, B and C.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Molecular Structure; Proline; Serine; Thiazoles | 1994 |
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor.
Topics: Actins; Adrenergic beta-Agonists; Binding Sites; Biotinylation; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cell Line; Endocytosis; Endosomes; Humans; Isoproterenol; Lysosomes; Molecular Sequence Data; Phosphoproteins; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, beta-2; Recombinant Proteins; Serine; Sodium-Hydrogen Exchangers; Thiazoles; Thiazolidines | 1999 |
Yersiniabactin synthetase: probing the recognition of carrier protein domains by the catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HWMP2 subunit.
Topics: Acyl Carrier Protein; Alanine; Amino Acid Isomerases; Amino Acid Substitution; Bacterial Outer Membrane Proteins; Bacterial Proteins; Catalytic Domain; Coenzyme A Ligases; Enzyme Activation; Iron-Binding Proteins; Molecular Weight; Peptide Chain Initiation, Translational; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Serine; Siderophores; Substrate Specificity; Thiazoles; Yersinia pestis | 2001 |
Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.
Topics: Alanine; Catalysis; Cysteine; Deuterium Oxide; Enzyme Activation; Hydrogen; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Solvents; Substrate Specificity; Thiamine Pyrophosphate; Thiazoles | 2001 |
IL-10 promotes survival of microglia without activating Akt.
Topics: Animals; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; DNA-Binding Proteins; Enzyme Activation; Insulin-Like Growth Factor I; Interleukin-10; Mice; Microglia; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Interleukin; Receptors, Interleukin-10; Serine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Trans-Activators; Tyrosine | 2002 |
Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cell Adhesion; Cell Division; Cell Line; Cells, Cultured; Cytochalasin D; Cytoskeleton; Dactinomycin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Humans; Immunoblotting; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Signal Transduction; Substrate Specificity; Thiazoles; Thiazolidines; Threonine; Time Factors; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine; Up-Regulation | 2002 |
Biosynthesis inspired Diels-Alder route to pyridines: synthesis of the 2,3-dithiazolylpyridine core of the thiopeptide antibiotics.
Topics: Anti-Bacterial Agents; Pyridines; Serine; Thiazoles; Thiostrepton | 2002 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Line; Coloring Agents; Cytochrome c Group; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Dominant; Green Fluorescent Proteins; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Luminescent Proteins; MAP Kinase Kinase 4; Membrane Potentials; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Multiple Myeloma; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
Ursolic acid induces apoptosis through caspase-3 activation and cell cycle arrest in HaCat cells.
Topics: Apoptosis; Caspase 3; Caspases; Catalysis; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Enzyme Activation; G1 Phase; Humans; Keratinocytes; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Triterpenes; Trypan Blue; Tumor Suppressor Protein p53; Ursolic Acid | 2003 |
PURINE METABOLISM IN THE CHICK EMBRYO: INFLUENCE OF 2-SUBSTITUTED THIADIAZOLES.
Topics: Abnormalities, Drug-Induced; Allantoin; Animals; Carbon Isotopes; Chick Embryo; Chromatography; Formates; Hypoxanthines; Insulin; Metabolism; Methionine; Methionine Sulfoximine; NAD; Niacin; Niacinamide; Nucleosides; Purines; Pyridines; Research; Serine; Sulfanilamide; Sulfanilamides; Thiadiazoles; Thiazoles; Toxicology; Triazines; Uric Acid; Uricosuric Agents | 1964 |
The 2-thio-5-thiazolidones of serine and arginine.
Topics: Arginine; Humans; Serine; Thiazoles | 1954 |
Manipulation of alternative splicing by a newly developed inhibitor of Clks.
Topics: Alternative Splicing; Animals; Arginine; Binding Sites; Cell Nucleus; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Globins; HeLa Cells; Humans; Microscopy, Fluorescence; Models, Chemical; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; Serine; Signal Transduction; Thiazoles; Time Factors; Xenopus; Xenopus laevis | 2004 |
Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Benzothiazoles; Caspase Inhibitors; Caspases; Cell Line, Tumor; Enzyme Activation; Humans; Male; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Serine; Sodium Selenite; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2004 |
Inactivation of glycogen synthase kinase-3beta protects against kainic acid-induced neurotoxicity in vivo.
Topics: Animals; Behavior, Animal; Blotting, Western; Butadienes; Cell Death; Cell Survival; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Lithium Chloride; Male; Mice; Mitogen-Activated Protein Kinase 1; Neurotoxicity Syndromes; Nitriles; Organ Culture Techniques; Phosphorylation; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2004 |
Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.
Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Humans; Membrane Potentials; Microscopy, Confocal; Minocycline; N-Methylaspartate; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2004 |
Palmitoylated cysteine 192 is required for RhoB tumor-suppressive and apoptotic activities.
Topics: Alanine; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cysteine; DNA Primers; Genes, Tumor Suppressor; Glycine; Humans; In Situ Nick-End Labeling; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Palmitic Acid; Promoter Regions, Genetic; Protein Biosynthesis; Protein Prenylation; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Sequence Homology, Amino Acid; Serine; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 2005 |
Glycogen synthase kinase 3beta links neuroprotection by 17beta-estradiol to key Alzheimer processes.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Blotting, Western; Cell Count; Cell Death; Cells, Cultured; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Agonists; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Phosphorylation; Pregnancy; Propidium; Rats; Rats, Sprague-Dawley; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Tyrosine | 2005 |
Molybdenum oxides as highly effective dehydrative cyclization catalysts for the synthesis of oxazolines and thiazolines.
Topics: Catalysis; Cyclization; Cysteine; Molybdenum; Oxazoles; Serine; Thiazoles; Threonine | 2005 |
The detection of salmochelin and yersiniabactin in uropathogenic Escherichia coli strains by a novel hydrolysis-fluorescence-detection (HFD) method.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Enterobactin; Escherichia coli; Glucosides; Humans; Hydrolysis; Iron; Phenols; Serine; Siderophores; Species Specificity; Thiazoles | 2005 |
Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.
Topics: Acetates; Animals; beta-Alanine; Cell Line; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Guanidines; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Molecular Structure; Neurotransmitter Uptake Inhibitors; Plasmids; Propionates; Serine; Structure-Activity Relationship; Thiazoles; Transfection; Tritium | 2005 |
Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues.
Topics: Aminobutyrates; Animals; Carboxylic Acids; Cells, Cultured; Cross-Linking Reagents; Dipeptides; Growth Hormone; Male; Methylation; Molecular Structure; Phenanthrenes; Pituitary Gland; Rats; Rats, Sprague-Dawley; Serine; Structure-Activity Relationship; Thiazoles | 2005 |
Chemoenzymatic approaches for streamlined detection of active site modifications on thiotemplate assembly lines using mass spectrometry.
Topics: Acylation; Binding Sites; Coenzyme A; Cyanogen Bromide; Escherichia coli Proteins; Fluorescent Dyes; Mass Spectrometry; Molecular Weight; Peptide Synthases; Phenols; Serine; Siderophores; Sulfhydryl Compounds; Thiazoles; Time Factors | 2005 |
Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells.
Topics: Adenoviridae; Apoptosis; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Benzothiazoles; Caspase 3; Caspases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Guanylate Cyclase; Half-Life; Humans; Mutation; Ovarian Neoplasms; Oxadiazoles; Phosphorylation; Proto-Oncogene Proteins c-mdm2; Quinoxalines; RNA, Small Interfering; Serine; Signal Transduction; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Male; Mice; Mice, Inbred C57BL; Olanzapine; Phosphorylation; Piperazines; Quetiapine Fumarate; Risperidone; Selective Serotonin Reuptake Inhibitors; Serine; Thiazoles; Time Factors | 2007 |
Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics.
Topics: Amino Acids; Azoles; Combinatorial Chemistry Techniques; Imidazoles; Molecular Mimicry; Oxazoles; Peptides; Serine; Thiazoles; Threonine | 2006 |
Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription.
Topics: Animals; Anthracenes; Aplysia; Apoptosis; Axotomy; Blotting, Western; Cells, Cultured; Cloning, Molecular; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Functional Laterality; Ganglia, Invertebrate; Green Fluorescent Proteins; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Microinjections; Neurons, Afferent; Protein Binding; Serine; Synapses; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2006 |
AG205, a novel agent directed against FabK of Streptococcus pneumoniae.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Escherichia coli; Genes, Bacterial; Humans; Inhibitory Concentration 50; Lipogenesis; Microbial Sensitivity Tests; Molecular Structure; Serine; Streptococcus pneumoniae; Structure-Activity Relationship; Thiazoles | 2006 |
The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Blotting, Western; Cell Fractionation; Cell Line, Tumor; Cell Survival; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression; Humans; Neuroblastoma; Neurotoxins; Phosphorylation; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Transfection | 2006 |
Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspases; Cell Survival; Cerebellum; Chelating Agents; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Activation; Focal Adhesion Kinase 2; Mice; Mutagenesis; Neurons; Potassium; Potassium Chloride; Serine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tyrosine | 2007 |
Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Benzimidazoles; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; Checkpoint Kinase 1; Checkpoint Kinase 2; Cisplatin; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Inhibitors; Humans; Immunoprecipitation; Mice; Molecular Structure; Paclitaxel; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Radiation, Ionizing; Recombinant Proteins; Serine; Thiazoles; Threonine; Tumor Suppressor Proteins | 2007 |
Elevated glycogen synthase kinase-3 activity in Fragile X mice: key metabolic regulator with evidence for treatment potential.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antimanic Agents; Brain; Citrates; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fragile X Mental Retardation Protein; Gene Expression Regulation; Glycogen Synthase Kinase 3; Indoles; Lithium Chloride; Male; Maleimides; Mice; Mice, Knockout; Pyridines; Seizures; Serine; Thiazoles; Urea | 2009 |
Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells.
Topics: Blotting, Western; CDC2 Protein Kinase; Cell Line, Tumor; Cell Nucleus; Cyclin B1; DNA Damage; Down-Regulation; HCT116 Cells; HeLa Cells; Host-Pathogen Interactions; Human papillomavirus 16; Human papillomavirus 18; Humans; Mitosis; Neoplasms; Phosphorylation; Quinolines; RNA Interference; Serine; Thiazoles; Tumor Suppressor Protein p53 | 2010 |
NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
Topics: Amino Acid Sequence; Catalysis; Dealkylation; Molecular Sequence Data; Molecular Structure; Protein Precursors; Serine; Streptomyces; Thiazoles | 2010 |
Design of novel and potent cPLA2α inhibitors containing an α-methyl-2-ketothiazole as a metabolically stable serine trap.
Topics: Animals; Drug Design; Drug Stability; Enzyme Activation; Enzyme Inhibitors; Group IV Phospholipases A2; HL-60 Cells; Humans; Inhibitory Concentration 50; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Rats; Serine; Thiazoles | 2011 |
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays | 2011 |
Human corneal endothelial cells employ phosphorylation of p27(Kip1) at both Ser10 and Thr187 sites for FGF-2-mediated cell proliferation via PI 3-kinase.
Topics: Adolescent; Adult; Aged; Butadienes; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Endothelium, Corneal; Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Confocal; Middle Aged; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Threonine; Tissue Donors; Transfection; Young Adult | 2011 |
Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; Aniline Compounds; Animals; Astrocytes; Atropine; Basal Nucleus of Meynert; Calcium Signaling; Cholinergic Agents; Chromatography, High Pressure Liquid; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Fluoresceins; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Knockout; Microdialysis; Muscarinic Antagonists; Nerve Growth Factors; Neuronal Plasticity; Neurons; Physical Stimulation; Piperazines; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serine; Somatosensory Cortex; Sulfonamides; Thiazoles; Vibrissae | 2011 |
The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; Dasatinib; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Genes, src; Growth Hormone; Humans; Mice; Mitochondria; Phosphorylation; Pituitary Neoplasms; Polymorphism, Single Nucleotide; Prolactin; Pyrimidines; Rats; Receptor, Fibroblast Growth Factor, Type 4; Serine; STAT3 Transcription Factor; Thiazoles | 2011 |
Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.
Topics: Adenine; Adjuvants, Immunologic; Aldehydes; Analysis of Variance; Animals; Asparagine; Autophagy; Brain; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Lithium Chloride; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphorylation; Serine; Sirolimus; Tetrazolium Salts; Thiazoles; Trimethyltin Compounds; Vacuoles | 2012 |
Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.
Topics: Amyloid beta-Protein Precursor; Animals; Aorta; Biopterins; Blotting, Western; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; GTP Cyclohydrolase; Humans; Membrane Glycoproteins; Mice; Mice, Transgenic; Microscopy, Confocal; Mutation; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; PPAR gamma; Prostaglandins; Serine; Superoxide Dismutase; Superoxides; Thiazoles; Vasodilation; Vasodilator Agents | 2012 |
Solid phase versus solution phase synthesis of heterocyclic macrocycles.
Topics: Cyclization; Cysteine; Leucine; Oxidation-Reduction; Peptides, Cyclic; Serine; Solid-Phase Synthesis Techniques; Solutions; Thiazoles | 2013 |
The C-terminal extended serine residue is absolutely required in nosiheptide maturation.
Topics: Amides; Amino Acid Sequence; Amino Acids; Serine; Thiazoles | 2013 |
An enzymatic route to selenazolines.
Topics: Amino Acid Sequence; Cysteine; Iodoacetamide; Multienzyme Complexes; Oxazoles; Peptides, Cyclic; Selenium; Selenocysteine; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles; Threonine | 2013 |
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.
Topics: Active Transport, Cell Nucleus; Amino Acid Motifs; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Female; Humans; Microscopy, Confocal; Phosphorylation; Proto-Oncogene Proteins c-fos; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles; Trans-Activators; Viral Regulatory and Accessory Proteins | 2013 |
Total synthesis and biological activity of natural product Urukthapelstatin A.
Topics: Biological Products; Inhibitory Concentration 50; Leucine; Molecular Structure; Serine; Stereoisomerism; Thiazoles | 2013 |
PKCɛ mediates serine phosphorylation of connexin43 induced by lysophosphatidylcholine in neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Survival; Coloring Agents; Connexin 43; Female; Fluorescent Antibody Technique; Heart Rate; Immunoprecipitation; Indoles; Lysophosphatidylcholines; Male; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Serine; Tetrazolium Salts; Thiazoles | 2013 |
Glycogen synthase kinase 3 beta regulates glial glutamate transporter protein expression in the spinal dorsal horn in rats with neuropathic pain.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Disease Models, Animal; Drug Administration Routes; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperalgesia; Interleukin-1beta; Male; Neurons; Oncogene Protein v-akt; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatica; Serine; Spinal Cord; Thiazoles; Time Factors; Urea | 2014 |
Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Binding Sites; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Hydrogen Bonding; Leucine; Meloxicam; Mice; Mutation; Piroxicam; Protein Structure, Secondary; Serine; Thiazines; Thiazoles; Tyrosine; Water | 2014 |
Cyclin-dependent kinase 5 phosphorylation of familial prion protein mutants exacerbates conversion into amyloid structure.
Topics: Amyloid; Benzothiazoles; Blotting, Western; Circular Dichroism; Cyclin-Dependent Kinase 5; Humans; Kinetics; Microscopy, Electron, Transmission; Mutation; Phosphorylation; Prions; Serine; Thiazoles | 2015 |
Potential Role of Glycogen Synthase Kinase-3β in Regulation of Myocardin Activity in Human Vascular Smooth Muscle Cells.
Topics: Actins; Calcium-Binding Proteins; Calponins; Cell Differentiation; Cell Line; Gene Expression Regulation; Gene Knockout Techniques; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Membrane Proteins; Microfilament Proteins; Muscle Proteins; Myocytes, Smooth Muscle; Nuclear Proteins; Phosphoproteins; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Recombinant Proteins; RNA, Small Interfering; Serine; Thiazoles; Threonine; Trans-Activators; Urea | 2016 |
Proteomic Profiling Reveals the Induction of UPR in Addition to DNA Damage Response in HeLa Cells Treated With the Thiazolo[5,4-b]Quinoline Derivative D3ClP.
Topics: Aminoquinolines; DNA Damage; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; HeLa Cells; Histones; Humans; Phosphorylation; Proteome; Proteomics; Serine; Thiazoles; Transcription Factor CHOP; Unfolded Protein Response | 2017 |
De novo formation of citrate-based fluorophores on N-termini of peptides and proteins in cells and tissues.
Topics: Animals; Cell Line, Tumor; Citric Acid; Cysteine; Fluorescence; Fluorescent Dyes; HEK293 Cells; Humans; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Probes; NIH 3T3 Cells; Peptides; Proof of Concept Study; Proteins; Pyridones; Serine; Thiazoles | 2020 |
Photoprotection by mitochondrial alternative pathway is enhanced at heat but disabled at chilling.
Topics: Arabidopsis; Chlorophyll A; Cold Temperature; Glycine; Hot Temperature; Light; Methacrylates; Mitochondria; Mitochondrial Proteins; Mutation; NADP; Oxidoreductases; Photosynthesis; Plant Leaves; Plant Proteins; Serine; Thiazoles | 2020 |
Targeting aurora kinase a (AURKA) in cancer: molecular docking and dynamic simulations of potential AURKA inhibitors.
Topics: Animals; Aurora Kinase A; Cell Line, Tumor; Humans; Mammals; Molecular Docking Simulation; Neoplasms; Piperazines; Serine; Thiazoles; Threonine | 2022 |