Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and sch-202676

thiazoles has been researched along with sch-202676 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benbow, LL; Fawzi, AB; Graziano, MP; Ho, G; Linder, ME; Macdonald, D; Smith-Torhan, A; Tulshian, D; Weig, BC; Zhang, H1
Christopoulos, A; Lanzafame, A1
Göblyös, A; Heitman, L; IJzerman, AP; Pietra, D; van den Nieuwendijk, AM1
Gao, ZG; Gross, AS; Jacobson, KA1
Schetz, JA1
Beukers, MW; de Grip, WJ; Ijzerman, AP; Klaasse, EC; Roerink, SF; van den Hout, G1
Laitinen, JT; Lewandowicz, AM; Vepsäläinen, J1
Farquharson, C; Harmey, D; Millán, JL; Narisawa, S; Roberts, S1

Reviews

1 review(s) available for thiazoles and sch-202676

ArticleYear
Allosteric modulation of dopamine receptors.
    Mini reviews in medicinal chemistry, 2005, Volume: 5, Issue:6

    Topics: Amiloride; Animals; Humans; Hydrogen; Peptides; Receptors, Dopamine; Sodium; Thiadiazoles; Thiazoles

2005

Other Studies

7 other study(ies) available for thiazoles and sch-202676

ArticleYear
SCH-202676: An allosteric modulator of both agonist and antagonist binding to G protein-coupled receptors.
    Molecular pharmacology, 2001, Volume: 59, Issue:1

    Topics: Adrenergic Agents; Allosteric Regulation; Escherichia coli; Guanosine 5'-O-(3-Thiotriphosphate); HT29 Cells; Humans; Radioligand Assay; Receptors, Adrenergic; Thiadiazoles; Thiazoles; Tumor Cells, Cultured

2001
Investigation of the interaction of a putative allosteric modulator, N-(2,3-diphenyl-1,2,4-thiadiazole-5-(2H)-ylidene) methanamine hydrobromide (SCH-202676), with M1 muscarinic acetylcholine receptors.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:3

    Topics: Allosteric Regulation; Animals; Binding Sites; Cell Membrane; CHO Cells; Cricetinae; Drug Interactions; Female; Hydrolysis; Kinetics; Radioligand Assay; Receptor, Muscarinic M1; Thiadiazoles; Thiazoles

2004
Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiadiazoles as allosteric modulators of adenosine receptors.
    Journal of medicinal chemistry, 2004, Jan-29, Volume: 47, Issue:3

    Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Allosteric Regulation; Animals; Binding, Competitive; Cell Line; Cricetinae; Humans; Kinetics; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Thiadiazoles; Thiazoles

2004
Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors.
    Life sciences, 2004, May-07, Volume: 74, Issue:25

    Topics: Allosteric Regulation; Animals; Astrocytoma; Binding, Competitive; Brain Neoplasms; Cells, Cultured; CHO Cells; Cricetinae; Humans; Kidney; Kinetics; Radioligand Assay; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thiadiazoles; Thiazoles

2004
Allosteric modulators affect the internalization of human adenosine A1 receptors.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Endocytosis; Humans; Luminescent Proteins; Microscopy, Confocal; Radioligand Assay; Receptor, Adenosine A1; Recombinant Fusion Proteins; Thiadiazoles; Thiazoles; Thiophenes; Transfection; Tritium; Xanthines

2005
The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.
    British journal of pharmacology, 2006, Volume: 147, Issue:4

    Topics: Allosteric Regulation; Animals; Autoradiography; Brain Chemistry; Cell Membrane; Guanosine 5'-O-(3-Thiotriphosphate); Male; Nuclear Magnetic Resonance, Biomolecular; Radioligand Assay; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Thiadiazoles; Thiazoles

2006
Functional involvement of PHOSPHO1 in matrix vesicle-mediated skeletal mineralization.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007, Volume: 22, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alkaline Phosphatase; Animals; Base Sequence; Bone Matrix; Calcification, Physiologic; Cells, Cultured; Chickens; DNA Primers; Enzyme Inhibitors; Growth Plate; Humans; Immunohistochemistry; In Vitro Techniques; Lansoprazole; Male; Mice; Mice, Knockout; Osteoblasts; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Thiadiazoles; Thiazoles

2007