thiazoles has been researched along with sb674042 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brough, SJ; Herdon, HJ; Jerman, JC; Langmead, CJ; Porter, RA; Scott, C | 1 |
| Canals, M; Ellis, J; Milasta, S; Milligan, G; Pediani, JD | 1 |
| Borroni, E; Knoflach, F; Malherbe, P; Pinard, E; Wettstein, JG | 1 |
| Bissantz, C; Kratzeisen, C; Malherbe, P; Marcuz, A; Roche, O; Wettstein, JG | 1 |
| Milligan, G; Pediani, JD; Ward, RJ | 1 |
| Babaoglu, K; Brautigam, CA; Clark, L; Coleman, PJ; Gotter, AL; Harrell, CM; Renger, JJ; Roecker, AJ; Rosenbaum, DM; Scheuermann, TH; Shao, Z; Winrow, CJ; Yin, J | 1 |
| Park, KB; Weon, H | 1 |
| Chang, X; Suo, L; Xu, N; Zhao, Y | 1 |
8 other study(ies) available for thiazoles and sb674042
| Article | Year |
|---|---|
Characterisation of the binding of [3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor.
Topics: Animals; Benzoxazoles; CHO Cells; Cricetinae; Humans; Naphthyridines; Orexin Receptors; Protein Binding; Pyrrolidines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Thiazoles; Tritium; Urea | 2004 |
Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function.
Topics: Base Sequence; Cell Line; Dimerization; DNA Primers; Humans; Ligands; Orexin Receptors; Pyrrolidines; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Thiazoles | 2006 |
Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with selective OX1 and OX2 antagonists.
Topics: Acetamides; Animals; Evoked Potentials; Humans; Isoquinolines; Kinetics; Molecular Structure; Neurons; Orexin Receptors; Phenylurea Compounds; Pyrrolidines; Rats; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Thiazoles | 2009 |
Mapping the binding pocket of dual antagonist almorexant to human orexin 1 and orexin 2 receptors: comparison with the selective OX1 antagonist SB-674042 and the selective OX2 antagonist N-ethyl-2-[(6-methoxy-pyridin-3-yl)-(toluene-2-sulfonyl)-amino]-N-py
Topics: Acetamides; Amino Acid Sequence; Aminopyridines; Binding Sites; Cell Line; Humans; Isoquinolines; Molecular Sequence Data; Mutagenesis, Site-Directed; Orexin Receptors; Pyrrolidines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sequence Homology, Amino Acid; Sulfonamides; Thiazoles | 2010 |
Ligand-induced internalization of the orexin OX(1) and cannabinoid CB(1) receptors assessed via N-terminal SNAP and CLIP-tagging.
Topics: Alkyl and Aryl Transferases; Benzoxazoles; Cell Line; Cell Membrane; Cloning, Molecular; Cyclohexanols; Extracellular Signal-Regulated MAP Kinases; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Phenylurea Compounds; Phosphorylation; Piperidines; Plasmids; Pyrazoles; Pyrrolidines; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Rimonabant; Thiazoles; Urea | 2011 |
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Topics: Azepines; Crystallography, X-Ray; Humans; Ligands; Models, Molecular; Orexin Receptor Antagonists; Orexin Receptors; Protein Binding; Protein Conformation; Pyrrolidines; Thiazoles; Triazoles | 2016 |
Orexin receptors mediate long-term depression of excitatory synaptic transmission in the spinal cord dorsal horn.
Topics: Aminopyridines; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Long-Term Synaptic Depression; Male; Orexin Receptor Antagonists; Orexin Receptors; Pyrrolidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Dorsal Horn; Sulfonamides; Thiazoles | 2017 |
Orexin-A Stimulates Insulin Secretion Through the Activation of the OX1 Receptor and Mammalian Target of Rapamycin in Rat Insulinoma Cells.
Topics: Animals; Cell Line, Tumor; Insulin Secretion; Insulinoma; Orexin Receptors; Orexins; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridones; Pyrimidines; Pyrrolidines; Rats; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases | 2019 |