thiazoles has been researched along with pyruvaldehyde in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Mizutani, T; Suzuki, K | 1 |
| Al-Abed, Y; Bucala, R; Ferguson, GP; VanPatten, S | 1 |
| Davies, GF; Juurlink, BH; Roesler, WJ; Wu, L | 1 |
| Chan, WH; Wu, HJ | 1 |
| Chen, K; Maley, J; Yu, PH | 1 |
| Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J | 1 |
| Lee, HJ; Lee, HK; Park, HT; Seo, IA; Suh, DJ | 1 |
| Clemens, L; Godfrey, T; Griffin, MD; Howlett, GJ; Januszewski, AS; Jenkins, AJ; Karschimkus, CS; Lee, AB; Mok, YF; Romas, E; Wilson, AM; Wilson, LM; Wong, M | 1 |
| Desai, KM; Dhar, A; Wu, L | 1 |
| Bobermin, LD; de Souza, DF; Fontoura, JB; Gonçalves, CA; Hansen, F; Hoefel, AL; Leite, MC; Perry, ML; Silveira, Sda L; Tramontina, AC | 1 |
| Ellis, EM; Li, D; Lyon, RC; McGarvie, G | 1 |
| de Lima, BO; Heimfarth, L; Loureiro, SO; Pessoa-Pureur, R; Pierozan, P; Reis, KP; Torres, EB | 1 |
| Dai, H; He, P; Hu, Y; Li, W; Ni, Z; Xu, H; Zhang, Z | 1 |
| Desai, KM; Dhar, A; Dhar, I; Wu, L | 1 |
| Bhat, A; Desai, KM; Dhar, A; Dhar, I | 1 |
| Babu, MS; Bhat, A; Desai, KM; Dhar, A; Dhar, I; Kalra, J; Malapati, P; Medapi, B; Sriram, D; Udumula, MP | 1 |
| Dong, L; Du, M; Guo, Y; Luo, XL; Ma, YJ; Wang, XY; Xu, XB; Yu, P | 1 |
| Akahane, H; Azuma, M; Chimori, R; Inoue, M; Kitajima, M; Mano, Y; Natani, S; Nishida, A; Takasawa, R; Tanuma, SI; Uchiro, H; Yoshimori, A | 1 |
| Hayat, K; Ho, CT; Liu, M; Xu, H; Yu, J; Zhang, X; Zhou, T | 1 |
19 other study(ies) available for thiazoles and pyruvaldehyde
| Article | Year |
|---|---|
Relative hepatotoxicity of 2-(substituted phenyl)thiazoles and substituted thiobenzamides in mice: evidence for the involvement of thiobenzamides as ring cleavage metabolites in the hepatotoxicity of 2-phenylthiazoles.
Topics: Alanine Transaminase; Animals; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Pyruvaldehyde; Structure-Activity Relationship; Thiazoles; Thioamides | 1996 |
Detoxification of methylglyoxal by the nucleophilic bidentate, phenylacylthiazolium bromide.
Topics: Antiporters; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Glutathione; Guanidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Potassium Channels; Potassium-Hydrogen Antiporters; Pyruvaldehyde; Thiazoles | 1999 |
Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide.
Topics: Animals; Brain; Cells, Cultured; Cerebrovascular Circulation; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycation End Products, Advanced; Hepatocytes; Humans; Hyperglycemia; Hypoglycemic Agents; Lactoylglutathione Lyase; Pyruvaldehyde; Rats; tert-Butylhydroperoxide; Thiazoles; Thiazolidinediones; Thiolester Hydrolases; Troglitazone; Up-Regulation | 2002 |
Genistein protects methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells.
Topics: Adult; Animals; Antimutagenic Agents; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Female; Genistein; Humans; Leukocytes, Mononuclear; Male; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2007 |
Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis.
Topics: Aldehydes; Alzheimer Disease; Amine Oxidase (Copper-Containing); Amyloid beta-Peptides; Benzothiazoles; Brain; Cell Adhesion Molecules; Fluorometry; Formaldehyde; Humans; Lipid Peroxidation; Malondialdehyde; Microscopy, Atomic Force; Neurofibrillary Tangles; Oxidative Stress; Polymers; Protein Folding; Proteomics; Pyruvaldehyde; Spectrum Analysis; Thiazoles | 2006 |
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan | 2008 |
A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Cytokine Receptor gp130; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Hydrogen Peroxide; Interleukin-6; Neuroglia; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2009 |
Thioflavin T fluorescence in human serum: correlations with vascular health and cardiovascular risk factors.
Topics: Adult; Amyloid beta-Peptides; Animals; Benzothiazoles; Biomarkers; Cardiovascular Diseases; Cattle; Fluorescence; Humans; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Serum Albumin; Thiazoles | 2010 |
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats.
Topics: Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Male; Phosphorylation; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrosine | 2010 |
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advanced; Glycine; Humans; Lactic Acid; Lactoylglutathione Lyase; Neutral Red; Oxidation-Reduction; Propidium; Pyruvaldehyde; Tetrazolium Salts; Thiazoles; Thiolester Hydrolases | 2012 |
Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells.
Topics: Adaptation, Physiological; Alcohol Oxidoreductases; Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Blotting, Western; Cell Line, Tumor; Coloring Agents; Enzyme Induction; Humans; Hydroquinones; Inactivation, Metabolic; Nerve Tissue Proteins; Pyruvaldehyde; RNA Interference; Tetrazolium Salts; Thiazoles | 2013 |
Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases.
Topics: Animals; Animals, Newborn; Annexin A5; Antioxidants; Blotting, Western; Brain; Cell Survival; Coloring Agents; Fluorescent Dyes; In Vitro Techniques; L-Lactate Dehydrogenase; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinases; Nerve Tissue Proteins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2013 |
Edaravone protected human brain microvascular endothelial cells from methylglyoxal-induced injury by inhibiting AGEs/RAGE/oxidative stress.
Topics: Antipyrine; Blotting, Western; Brain; Diabetes Complications; Edaravone; Endothelial Cells; Glycation End Products, Advanced; Humans; Microvessels; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Rhodamine 123; Tetrazolium Salts; Thiazoles | 2013 |
Methylglyoxal, a reactive glucose metabolite, increases renin angiotensin aldosterone and blood pressure in male Sprague-Dawley rats.
Topics: Aldosterone; Angiotensins; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholamines; Cells, Cultured; Disease Models, Animal; Hypertension; Male; NF-kappa B; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Signal Transduction; Thiazoles; Time Factors; Up-Regulation | 2014 |
Alagebrium attenuates methylglyoxal induced oxidative stress and AGE formation in H9C2 cardiac myocytes.
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cells, Cultured; Free Radical Scavengers; Glucose; Glycation End Products, Advanced; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; Pyruvaldehyde; Rats; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Thiazoles | 2016 |
Pharmacological evaluation of novel alagebrium analogs as methylglyoxal scavengers in vitro in cardiac myocytes and in vivo in SD rats.
Topics: Animals; Cells, Cultured; Drug Evaluation, Preclinical; Glycation End Products, Advanced; Male; Myocytes, Cardiac; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiazoles | 2016 |
Reinvestigation of 2-acetylthiazole formation pathways in the Maillard reaction.
Topics: Chromatography, High Pressure Liquid; Cysteine; Glucose; Glyoxal; Maillard Reaction; Odorants; Pyruvaldehyde; Tandem Mass Spectrometry; Thiazoles | 2021 |
Addition of hydrophobic side chains improve the apoptosis inducibility of the human glyoxalase I inhibitor, TLSC702.
Topics: Apoptosis; Benzene; Butyrates; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Glutathione; Humans; Hydrophobic and Hydrophilic Interactions; Lactoylglutathione Lyase; Molecular Structure; Protein Binding; Pyruvaldehyde; Structure-Activity Relationship; Thiazoles | 2021 |
Formation Priority of Pyrazines and 2-Acetylthiazole Dependent on the Added Cysteine and Fragments of Deoxyosones during the Thermal Process of the Glycine-Ribose Amadori Compound.
Topics: Cysteamine; Cysteine; Glycine; Glyoxal; Magnesium Oxide; Maillard Reaction; Pyrazines; Pyruvaldehyde; Ribose; Thiazoles | 2022 |