Page last updated: 2024-08-21

thiazoles and pk 11195

thiazoles has been researched along with pk 11195 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's5 (35.71)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cesura, AM; Chan-Palay, V; Da Prada, M; Huber, G; Löffler, J; Luque, JM; Richards, JG; Saura, J1
Chen, J; Dai, Q; Freeman, A; Lee, RM; Liu, J1
Archer, HA; Brooks, DJ; Edison, P; Fox, N; Gerhard, A; Hammers, A; Hinz, R; Kennedy, A; Pavese, N; Rossor, M; Tai, YF; Turkheimer, FE1
Boellaard, R; Lammertsma, AA; Lubberink, M; Mourik, JE; Schuitemaker, A; Tolboom, N; van Berckel, BN1
Archer, HA; Brooks, DJ; Bullock, R; Edison, P; Fox, N; Kennedy, A; Kennedy, J; Okello, A; Rossor, M; Turkheimer, FE; Walker, Z1
DeKosky, ST; Klunk, WE; Lopresti, BJ; Mathis, CA; Price, J; Venneti, S; Wiley, CA1
Bergfors, A; Gillberg, PG; Marutle, A; Nennesmo, I; Ni, R; Nordberg, A; Voytenko, L; Yu, W1
Arlicot, N; Beaufils, E; Camus, V; Chalon, S; Corcia, P; Gosselin, T; Guilloteau, D; Hommet, C; Minier, F; Mondon, K; Paccalin, M; Page, G; Ribeiro, MJ1
Carazo, A; Pávek, P1
Brooks, DJ; Edison, P; Fan, Z; Okello, AA1
Inaba, M; Inouye, Y; Kanno, Y; Nakamura, S; Nemoto, K; Tanuma, N; Yazawa, S; Zhao, S1
Lynch, C; Wang, H; Xia, M; Zhao, J1
Brooks, DJ; Edison, P; Fan, Z; Okello, A1
Aanerud, J; Amidi, A; Borghammer, P; Brooks, DJ; Brændgaard, H; Edison, P; Eriksson, BO; Eskildsen, SF; Gottrup, H; Hansen, KV; Hinz, R; Ismail, R; Lund, TE; Mårup, FH; Parbo, P; Pavese, N; Stokholm, MG; Tietze, A1

Reviews

1 review(s) available for thiazoles and pk 11195

ArticleYear
Neuroinflammation and β amyloid deposition in Alzheimer's disease: in vivo quantification with molecular imaging.
    Dementia and geriatric cognitive disorders, 2014, Volume: 37, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain; Humans; Inflammation; Isoquinolines; Mitochondrial ADP, ATP Translocases; Molecular Imaging; Monoamine Oxidase; Positron-Emission Tomography; Radiopharmaceuticals; tau Proteins; Thiazoles

2014

Other Studies

13 other study(ies) available for thiazoles and pk 11195

ArticleYear
Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography.
    Neuroscience, 1994, Volume: 62, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Autoradiography; Brain; Female; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Isoquinolines; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Picolinic Acids; Thiazoles

1994
The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Benzopyrans; Blotting, Western; Caspase Inhibitors; Caspases; Cell Survival; Cell-Free System; Cells, Cultured; Coloring Agents; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; In Situ Nick-End Labeling; Isoquinolines; Mice; Microscopy, Fluorescence; Mitochondria; Nitriles; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors

2002
Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study.
    Neurobiology of disease, 2008, Volume: 32, Issue:3

    Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Carbon Radioisotopes; Cerebral Cortex; Cluster Analysis; Cognition; Female; Humans; Isoquinolines; Magnetic Resonance Imaging; Male; Microglia; Middle Aged; Positron-Emission Tomography; Thiazoles

2008
Image-derived input functions for PET brain studies.
    European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:3

    Topics: Aniline Compounds; Benzothiazoles; Brain; Carbon Radioisotopes; Humans; Image Processing, Computer-Assisted; Isoquinolines; Positron-Emission Tomography; Radiopharmaceuticals; Thiazoles; Verapamil

2009
Microglial activation and amyloid deposition in mild cognitive impairment: a PET study.
    Neurology, 2009, Jan-06, Volume: 72, Issue:1

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzothiazoles; Brain Mapping; Carbon Radioisotopes; Cognition Disorders; Female; Follow-Up Studies; Humans; Isoquinolines; Magnetic Resonance Imaging; Male; Microglia; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles

2009
Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.
    Archives of neurology, 2009, Volume: 66, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Antineoplastic Agents; Brain; Carbon Radioisotopes; Cognition Disorders; Disease Progression; Encephalitis; Female; Gliosis; Humans; Isoquinolines; Male; Microglia; Middle Aged; Plaque, Amyloid; Positron-Emission Tomography; Predictive Value of Tests; Thiazoles

2009
³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain.
    Journal of neuroinflammation, 2013, Jul-23, Volume: 10

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Astrocytes; Autoradiography; Benzothiazoles; Bungarotoxins; Cerebral Cortex; Female; Hippocampus; Humans; Immunohistochemistry; Isoquinolines; Isotope Labeling; Male; Nicotine; Parasympathetic Nervous System; Radionuclide Imaging; Receptors, Nicotinic; Selegiline; Synaptic Transmission; Thiazoles

2013
The Use of the LanthaScreen TR-FRET CAR Coactivator Assay in the Characterization of Constitutive Androstane Receptor (CAR) Inverse Agonists.
    Sensors (Basel, Switzerland), 2015, Apr-21, Volume: 15, Issue:4

    Topics: Biological Assay; Cell Line, Tumor; Clotrimazole; Constitutive Androstane Receptor; Humans; Isoquinolines; Oximes; Receptors, Cytoplasmic and Nuclear; Thiazoles

2015
Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer's disease.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 12

    Topics: Aged; Alzheimer Disease; Amyloid; Aniline Compounds; Brain; Case-Control Studies; Disease Progression; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Functional Neuroimaging; Glucose; Humans; Isoquinolines; Male; Microglia; Middle Aged; Neurons; Positron-Emission Tomography; Thiazoles

2015
Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Partial Agonism; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Hep G2 Cells; Humans; Isoquinolines; Ligands; Oximes; Pregnane X Receptor; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; RNA, Messenger; Thiazoles; Transfection

2016
Quantitative High-Throughput Luciferase Screening in Identifying CAR Modulators.
    Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1473

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Cell Line; Cell Nucleus; Cell Survival; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytoplasm; Founder Effect; Gene Expression Regulation; Hep G2 Cells; High-Throughput Screening Assays; Humans; Isoquinolines; Luciferases; Oximes; Plasmids; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transfection

2016
An early and late peak in microglial activation in Alzheimer's disease trajectory.
    Brain : a journal of neurology, 2017, 03-01, Volume: 140, Issue:3

    Topics: Aged; Alzheimer Disease; Aniline Compounds; Antineoplastic Agents; Brain Mapping; Carbon Radioisotopes; Cognition Disorders; Cohort Studies; Female; Humans; Imaging, Three-Dimensional; Isoquinolines; Magnetic Resonance Imaging; Male; Microglia; Middle Aged; Positron-Emission Tomography; Thiazoles

2017
Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease.
    Brain : a journal of neurology, 2017, Jul-01, Volume: 140, Issue:7

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Aniline Compounds; Case-Control Studies; Cerebral Cortex; Cognitive Dysfunction; Disease Progression; Encephalitis; Female; Humans; Isoquinolines; Male; Microglia; Middle Aged; Neuropsychological Tests; Positron-Emission Tomography; Thiazoles

2017