thiazoles has been researched along with phosphotyrosine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (28.57) | 18.2507 |
| 2000's | 16 (57.14) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J; Piotrowski, J; Slomiany, A; Slomiany, BL | 1 |
| Berti, L; Häring, H; Kellerer, M; Kiehn, R; Kroder, G; Mosthaf, L; Tippmer, S | 1 |
| Bleasdale, JE; Jacob, CS; Sizer, KM; Smith, CL; Swanson, ML | 1 |
| Egawa, K; Hasegawa, M; Ide, R; Iwanishi, M; Kashiwagi, A; Kikkawa, R; Maegawa, H; Shigeta, Y; Ugi, S | 1 |
| Hayakawa, T; Ikeda, H; Morimoto, T; Shii, K; Shiraki, T | 1 |
| Becker, D; Knop, J; Kühn, U; van Brandwijk, R; Willemsen, J | 1 |
| Andrews, KM; Genereux, PE; Gibbs, EM; Kreutter, DK; Stevenson, RW | 1 |
| Ozawa, T; Sato, M; Sugawara, M; Umezawa, Y | 1 |
| D'Cruz, OJ; Uckun, FM; Vassilev, A | 1 |
| Haruta, T; Ishibashi, O; Iwata, M; Kawahara, J; Kobayashi, M; Sasaoka, T; Takano, A; Takata, Y; Ueno, E; Uno, T; Usui, I | 1 |
| Leopoldt, D; Rozengurt, E; Yee, HF | 1 |
| Helenius, A; Pelkmans, L; Püntener, D | 1 |
| Berger, J; Dallas-Yang, Q; Doebber, T; Jiang, G; Li, Z; Liu, F; Moller, DE; Shen, X; Szalkowski, D; Wu, M; Zhang, BB; Zhou, G | 1 |
| Gooding, WE; Grandis, JR; Li, M; Lui, VW; Niwa, H; Wentzel, AL | 1 |
| Craig, AW; Di Ciano-Oliveira, C; Fan, L; Greer, PA; Kapus, A; Rotstein, OD; Weed, SA | 1 |
| Geiger, B; Volberg, T; Zimerman, B | 1 |
| Kuret, J; Necula, M | 1 |
| Deininger, MW; Druker, BJ; Heinrich, MC; O'Hare, T; Sherbenou, DW; Stoffregen, EP; Walters, DK | 1 |
| Ala, PJ; Becker-Pasha, M; Blom, K; Bostrom, L; Bower, M; Burn, TC; Combs, AP; Crawley, ML; Douty, B; Galya, L; Glass, B; Gonneville, L; Hillman, M; Hollis, G; Huber, R; Klabe, R; Li, M; Li, Y; Liu, P; McLaughlin, E; Metcalf, B; Modi, D; Polam, P; Pruitt, J; Reid, BG; Sparks, R; Takvorian, A; Wasserman, Z; Wayland, B; Wei, M; Wynn, R; Yue, EW; Zhu, W | 1 |
| Combs, AP; Crawley, ML; McLaughlin, E; Zhu, W | 1 |
| Ala, PJ; Bower, M; Burn, TC; Combs, AP; Crawley, ML; Ellis, D; Emm, T; Glass, B; Gonneville, L; Hollis, G; Li, Y; Liu, PC; McLaughlin, E; Metcalf, B; Modi, D; Polam, P; Reid, BM; Rupar, M; Sparks, RB; Takvorian, A; Taylor, N; Wasserman, Z; Wei, M; Wynn, R; Yeleswaram, S; Yue, EW; Zhu, W | 1 |
| Combs, AP; Galya, LG; Glass, B; Li, M | 1 |
| Bhalla, K; Jove, R; Lee, FY; List, A; Nam, S; Smith, D; Vultur, A; Williams, A | 1 |
| Bewry, NN; Boulware, D; Emmons, MF; Hazlehurst, LA; Nair, RR; Pinilla-Ibarz, J | 1 |
| Bongarzone, I; Caccia, D; Carniti, C; De Bortoli, M; Miccichè, F; Mondellini, P; Zanetti Domingues, L | 1 |
| Combs, CK; Dhawan, G; Floden, AM | 1 |
| Coffey, RJ; Hanks, SK; Liu, H; Luo, W; Manning, HC; McDonald, WH; McKinley, ET; Zhao, P | 1 |
| Dagger, SA; Duyvestyn, JM; Langdon, WY; Morse, HC; Orandle, M; Taylor, SJ; Thien, CB | 1 |
28 other study(ies) available for thiazoles and phosphotyrosine
| Article | Year |
|---|---|
Inhibition of EGF-induced gastric mucosal calcium channel phosphorylation by ebrotidine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Ulcer Agents; Benzenesulfonates; Calcium Channels; Calcium Radioisotopes; Epidermal Growth Factor; Gastric Mucosa; Isradipine; Phosphorylation; Phosphotyrosine; Rats; Thiazoles; Tyrosine | 1992 |
Troglitazone prevents glucose-induced insulin resistance of insulin receptor in rat-1 fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chromans; Fibroblasts; Glucose; Humans; Hypoglycemic Agents; Immunoblotting; Immunosorbent Techniques; Insulin Resistance; Isoquinolines; Kinetics; Phosphorylation; Phosphotyrosine; Piperazines; Rats; Receptor, Insulin; Thiazoles; Thiazolidinediones; Troglitazone; Tyrosine | 1994 |
Pioglitazone promotes insulin-induced activation of phosphoinositide 3-kinase in 3T3-L1 adipocytes by inhibiting a negative control mechanism.
Topics: 1-Phosphatidylinositol 4-Kinase; 3',5'-Cyclic-AMP Phosphodiesterases; 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cyclic AMP; Enzyme Activation; Hypoglycemic Agents; Immunosorbent Techniques; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Kinetics; Male; Mice; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Thiazoles; Thiazolidinediones; Tyrosine | 1994 |
Thiazolidine derivatives ameliorate high glucose-induced insulin resistance via the normalization of protein-tyrosine phosphatase activities.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blotting, Western; Cell Line; Cytosol; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Macromolecular Substances; Phosphotyrosine; Pioglitazone; Protein Tyrosine Phosphatases; Raffinose; Rats; Receptor, Insulin; Recombinant Proteins; Swine; Thiazoles; Thiazolidinediones; Transfection; Tyrosine | 1995 |
Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats.
Topics: Animals; Blood Glucose; Body Weight; Gene Expression; Hindlimb; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Male; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Pioglitazone; Rats; Rats, Mutant Strains; Rats, Wistar; Receptor, Insulin; Reference Values; Signal Transduction; Thiazoles; Thiazolidinediones; Triglycerides | 1996 |
Increased level of phosphotyrosine in human dendritic cells under stimulation with contact sensitizers but not irritants.
Topics: Animals; Dendritic Cells; Dermatitis, Contact; Haptens; Humans; In Vitro Techniques; Irritants; Mice; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Thiazoles; Tyrosine | 1997 |
Possibility of distinct insulin-signaling pathways beyond phosphatidylinositol 3-kinase-mediating glucose transport and lipogenesis.
Topics: 3T3 Cells; Animals; Benzopyrans; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Deoxyglucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Lipids; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Signal Transduction; Thiazoles; Thiazolidinediones | 1998 |
An assay method for evaluating chemical selectivity of agonists for insulin signaling pathways based on agonist-induced phosphorylation of a target peptide.
Topics: Amino Acids; Antibodies, Monoclonal; Avidin; Biotinylation; Chromans; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Hypoglycemic Agents; Insulin; Nitriles; Phosphorylation; Phosphotyrosine; Placenta; Receptor, Insulin; Spectrometry, Fluorescence; Thiazoles; Thiazolidinediones; Troglitazone; Tyrphostins | 1998 |
Studies in humans on the mechanism of potent spermicidal and apoptosis-inducing activities of vanadocene complexes.
Topics: Apoptosis; Biomechanical Phenomena; Blotting, Western; Coloring Agents; DNA Fragmentation; Dyneins; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; In Vitro Techniques; Male; Membrane Potentials; Phosphates; Phosphotyrosine; Sperm Motility; Spermatocidal Agents; Spermatozoa; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vagina; Vanadium Compounds | 2000 |
Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Cell Line; Deoxyglucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Transforming Growth Factor alpha | 2001 |
Calyculin-A induces focal adhesion assembly and tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin in Swiss 3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Animals; Bombesin; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Crk-Associated Substrate Protein; Cytochalasin D; Cytoskeletal Proteins; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Immunoblotting; Indoles; Maleimides; Marine Toxins; Mice; Microscopy, Fluorescence; Myosin-Light-Chain Phosphatase; Nucleic Acid Synthesis Inhibitors; Oxazoles; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Thiazoles; Thiazolidines; Time Factors | 2001 |
Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Caveolae; Caveolin 1; Caveolins; Cell Line; Cholesterol; Depsipeptides; Dynamins; Endocytosis; GTP Phosphohydrolases; Haplorhini; Peptides, Cyclic; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Simian virus 40; Stress Fibers; Thiazoles; Thiazolidines; Transport Vesicles | 2002 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Topics: Adipose Tissue; Animals; Fatty Acids, Nonesterified; Female; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Coloring Agents; DNA-Binding Proteins; Docetaxel; Dose-Response Relationship, Drug; Down-Regulation; ErbB Receptors; Female; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Transplantation; Oligonucleotides, Antisense; Phosphotyrosine; Signal Transduction; STAT3 Transcription Factor; Taxoids; Tetrazolium Salts; Thiazoles; Time Factors; Trans-Activators; Vascular Endothelial Growth Factor A | 2003 |
Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cortactin; Cricetinae; Enzyme Activation; Microfilament Proteins; Osmotic Pressure; Peptides; Phosphorylation; Phosphotyrosine; Polymers; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Thiazoles; Thiazolidines; Transfection; Tyrosine | 2004 |
Early molecular events in the assembly of the focal adhesion-stress fiber complex during fibroblast spreading.
Topics: Actin Cytoskeleton; Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cell Movement; Cells, Cultured; Cytoskeletal Proteins; Cytoskeleton; Extracellular Matrix; Fibroblasts; Focal Adhesions; Humans; Integrin alphaVbeta3; Integrins; Male; Microscopy, Electron, Scanning; Microscopy, Video; Paxillin; Phosphoproteins; Phosphotyrosine; Rats; Stress Fibers; Stress, Mechanical; Thiazoles; Thiazolidines; Time Factors; Vinculin | 2004 |
Site-specific pseudophosphorylation modulates the rate of tau filament dissociation.
Topics: Benzothiazoles; Humans; Kinetics; Mutation; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Quaternary; tau Proteins; Thiazoles | 2005 |
Combined Abl inhibitor therapy for minimizing drug resistance in chronic myeloid leukemia: Src/Abl inhibitors are compatible with imatinib.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Dasatinib; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Genetic Vectors; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Immunoblotting; Inhibitory Concentration 50; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Phosphotyrosine; Piperazines; Point Mutation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-abl; Pyrimidines; src-Family Kinases; Stem Cells; Thiazoles; Time Factors | 2005 |
Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.
Topics: Crystallography, X-Ray; Dipeptides; Drug Design; Models, Molecular; Molecular Mimicry; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Quantitative Structure-Activity Relationship; Stereoisomerism; Thiazoles | 2005 |
Concise approach to novel isothiazolidinone phosphotyrosine mimetics: microwave-assisted addition of bisulfite to activated olefins.
Topics: Alkenes; Microwaves; Molecular Mimicry; Molecular Structure; Phosphotyrosine; Sulfites; Thiazoles | 2005 |
Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.
Topics: Benzimidazoles; Cell Line; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Mimicry; Molecular Structure; Oligopeptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2006 |
Asymmetric synthesis of the (S)-1,1-dioxido-isothiazolidin-3-one phosphotyrosine mimetic via reduction of a homochiral (R)-oxido-isothiazolidin-3-one.
Topics: Enzyme Inhibitors; Models, Molecular; Molecular Mimicry; Molecular Structure; Phosphotyrosine; Protein Tyrosine Phosphatases; Stereoisomerism; Thiazoles | 2007 |
Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.
Topics: Apoptosis; bcl-X Protein; Cell Count; Cell Survival; Cyclin D1; Dasatinib; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; HL-60 Cells; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphotyrosine; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Thiazoles | 2007 |
Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance.
Topics: Benzamides; Bone Marrow; Cell Death; Cell Line, Tumor; Culture Media, Conditioned; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Pyrimidines; RNA, Small Interfering; STAT3 Transcription Factor; Thiazoles | 2008 |
Secretome compartment is a valuable source of biomarkers for cancer-relevant pathways.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Line, Tumor; Cluster Analysis; Computational Biology; Dasatinib; Databases, Protein; Humans; Intracellular Space; Models, Biological; Neoplasm Proteins; Neoplasms; Phosphotyrosine; Proteome; Pyrimidines; Signal Transduction; Thiazoles; Transforming Growth Factor beta | 2011 |
Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cells, Cultured; Dasatinib; Female; Humans; Male; Mice; Mice, Inbred C57BL; Microglia; Phosphotyrosine; Plaque, Amyloid; Polymers; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer.
Topics: Animals; Antigens, CD; Antigens, Neoplasm; Biomarkers, Tumor; Caco-2 Cells; Cell Adhesion Molecules; Cell Line, Tumor; Colorectal Neoplasms; Dasatinib; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasm Proteins; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphotyrosine; Protein Kinase C-delta; Protein Kinase Inhibitors; Proteome; Proteomics; Pyrimidines; Receptor-Like Protein Tyrosine Phosphatases, Class 5; src-Family Kinases; Thiazoles | 2013 |
Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.
Topics: Animals; B-Lymphocytes; Bone Marrow Cells; Cell Lineage; Dasatinib; Dose-Response Relationship, Drug; Germinal Center; Hematopoietic Stem Cells; Humans; Lymphocyte Count; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Myeloproliferative Disorders; Neutrophils; Phosphorylation; Phosphotyrosine; Precursor Cells, B-Lymphoid; Proto-Oncogene Proteins c-cbl; Pyrimidines; RING Finger Domains; src-Family Kinases; Thiazoles | 2014 |