thiazoles has been researched along with pd 98059 in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 24 (66.67) | 29.6817 |
| 2010's | 9 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Car, BD; Meunier, PC; Schnyder, B | 1 |
| Horie, T; Mori, M; Shimizu, H; Tsuchiya, T | 1 |
| Akimoto, K; Hattori, Y; Kasai, K | 1 |
| Chandraratna, RA; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kim, S; Kintscher, U; Law, RE; Nagpal, S; Wakino, S | 1 |
| Bais, C; Gutkind, JS; Mesri, EA; Montaner, S; Patel, V; Sodhi, A; Zohar, M | 1 |
| Dixon, C; Hilbelink, T; Lu, L; Rovin, BH; Wilmer, WA | 1 |
| Greenberg, AS; Rosenstock, M; Rudich, A | 1 |
| Collins, AR; Hsueh, WA; Jackson, S; Kintscher, U; Law, RE; Meehan, WP; Noh, G; Palinski, W; Wakino, S | 1 |
| Ahn, Y; Choi, KY; Kim, HI; Kim, JA; Oh, JW; Oh, SY; Park, KS | 1 |
| Blaschke, F; Bungenstock, A; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Stawowy, P | 1 |
| Kamata, T; Kobayashi, T; Michikawa, M; Mizusawa, H; Muramatsu, H; Muramatsu, T; Owada, K; Sanjyo, N | 1 |
| Dosoretz, A; Holland, JF; Kirschenbaum, A; Levine, AC; Liu, XH; Lu, M; Yao, S | 1 |
| Bungenstock, A; Czupalla, C; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Nürnberg, B; Spencer-Hänsch, C; Stawowy, P | 1 |
| Eggo, MC; Holder, JC; Kumar, S; Patel, NG; Smith, SA | 1 |
| Choi, JY; Kim, HJ; Kim, SY; Lee, MH; Lee, SW; Park, HS; Park, MH; Ryoo, HM; Shin, HI | 1 |
| Ding, SJ; Hsu, TC; Huang, TH; Kao, CT | 1 |
| Dai, J; Remick, DG; Wang, X; Zeng, X | 1 |
| Amin, AR; Biswas, MH; Hamaguchi, M; Huang, P; Ichigotani, Y; Mon, NN; Oo, ML; Yuan, H | 1 |
| Chen, YC; Hsu, KC; Ko, CH; Shen, SC | 1 |
| Cheng, JJ; Huang, NK; Lai, WL; Lin, YL | 1 |
| Aguilera, J; Chaïb-Oukadour, I; Gil, C | 1 |
| Liot, G; Lobner, D | 1 |
| Al-Khalili, L; Ehrenborg, E; Kannisto, K; Krämer, DK; Krook, A; Perrini, S; Skogsberg, J; Wallberg-Henriksson, H; Wretenberg, P; Zierath, JR | 1 |
| Herrera-Molina, R; Saud, K; Von Bernhardi, R | 1 |
| Chang, YC; Ho, YC | 1 |
| Gajkowska, B; Hocquette, JF; Orzechowski, A; Pawlikowska, P | 1 |
| Cordova, FM; Costa, AP; Leal, RB; Oliveira, CS; Posser, T; Rigon, AP; Rocha, JB; Rossi, FM; Santos, DA; Silva, IG | 1 |
| Hiramatsu, Y; Masuyama, H; Nakatsukasa, H | 1 |
| Huss, JM; Murray, J | 1 |
| Chen, X; Duan, L; He, T; Luo, J; Shi, Q; Tang, M; Wang, H; Weng, Y; Wu, R; Yang, X; Ye, L; Zhang, Y; Zhou, L | 1 |
| Anand-Srivastava, MB; El Andalousi, J; Li, Y | 1 |
| Byagowi, S; Darabi, M; Fayezi, S; Mirshahvaladi, S; Sahmani, M | 1 |
| Crews, LA; Gonzales, T; Kouznetsova, VL; Masliah, E; Overk, CR; Patrick, C; Paulino, A; Price, D; Rockenstein, E; Stocking, E; Tsigelny, IF; Wrasidlo, W | 1 |
| Byagowi, S; Darabi, M; Fayezi, S; Mirshahvaladi, S; Najafipour, R; Naserpour Farivar, T; Sahmani, M | 1 |
| Baxter, RC; Pavlakis, N; Smith, RC; Wong, MH; Xue, A | 1 |
| Chen, S; Huang, H; Huang, Q; Huang, W; Lin, M; Lin, W | 1 |
36 other study(ies) available for thiazoles and pd 98059
| Article | Year |
|---|---|
Inhibition of kinases impairs neutrophil activation and killing of Staphylococcus aureus.
Topics: Androstadienes; Blood Bactericidal Activity; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Respiratory Burst; Staphylococcus aureus; Thiazoles; Wortmannin | 1998 |
Expression of leptin receptor in lung: leptin as a growth factor.
Topics: Animals; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Division; Cells, Cultured; Coloring Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Mice; Obesity; Proteins; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II.
Topics: Angiotensin II; Animals; Enzyme Inhibitors; Flavonoids; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Thiazoles; Transcription Factor AP-1 | 2000 |
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Cell Movement; Chemokine CCL2; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Monocytes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2000 |
The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; DNA-Binding Proteins; Endothelial Growth Factors; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Lymphokines; MAP Kinase Kinase 6; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Chemokine; Response Elements; Sarcoma, Kaposi; Thiazoles; Transcription Factors; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Viral Proteins | 2000 |
A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glomerular Mesangium; Humans; Hypoglycemic Agents; Immunologic Factors; JNK Mitogen-Activated Protein Kinases; Ligands; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Prostaglandin D2; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2001 |
Distinct long-term regulation of glycerol and non-esterified fatty acid release by insulin and TNF-alpha in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Adrenergic beta-Agonists; Animals; Blood Glucose; Cell Membrane; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Nonesterified; Flavonoids; Glucose Transporter Type 4; Glycerol; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Lipolysis; Mice; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Morpholines; Muscle Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Arteriosclerosis; Blood Glucose; Body Weight; Cell Movement; Cells, Cultured; Chemokine CCL2; Chromans; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Endothelium, Vascular; Flavonoids; Fructose; Humans; Insulin; Lipids; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Receptors, LDL; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured; Vasodilator Agents | 2001 |
Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells.
Topics: Blotting, Western; Bromodeoxyuridine; Cell Division; Cell Nucleus; Chromans; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; HT29 Cells; Humans; Luciferases; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
PPAR activators inhibit endothelial cell migration by targeting Akt.
Topics: Apoptosis; Blotting, Western; Cell Movement; Cells, Cultured; Chromans; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fenofibrate; Flavonoids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; In Situ Nick-End Labeling; Lipid Metabolism; Lymphokines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peroxisome Proliferators; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2002 |
Midkine inhibits apoptosis via extracellular signal regulated kinase (ERK) activation in PC12 cells.
Topics: Animals; Apoptosis; Blotting, Western; Carrier Proteins; Coloring Agents; Culture Media, Serum-Free; Cytokines; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; In Situ Nick-End Labeling; MAP Kinase Signaling System; Midkine; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Neuroprotective Agents; PC12 Cells; Rats; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 1999 |
Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line.
Topics: Active Transport, Cell Nucleus; Arachidonic Acid; Catalysis; Cell Nucleus; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids; Green Fluorescent Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Intercellular Signaling Peptides and Proteins; Isoenzymes; Luminescent Proteins; Lymphokines; Male; MAP Kinase Signaling System; Meloxicam; Membrane Proteins; Nitrobenzenes; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiazines; Thiazoles; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands.
Topics: Androstadienes; Cell Line; Cell Movement; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Leptin; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins; Wortmannin | 2002 |
Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Topics: Adipocytes; Androstadienes; Cell Differentiation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leptin; Lipid Metabolism; Lipids; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rosiglitazone; Signal Transduction; Sirolimus; Stem Cells; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha; Wortmannin | 2003 |
Erk pathway and activator protein 1 play crucial roles in FGF2-stimulated premature cranial suture closure.
Topics: Amino Acid Motifs; Animals; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Nucleus; Cells, Cultured; Coloring Agents; Craniosynostoses; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Humans; In Situ Hybridization; Mice; Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; Osteoblasts; Osteopontin; Promoter Regions, Genetic; RNA; RNA, Messenger; Sialoglycoproteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2003 |
Effects of mineral trioxide aggregate (MTA) extracts on mitogen-activated protein kinase activity in human osteosarcoma cell line (U2OS).
Topics: Aluminum Compounds; Analysis of Variance; Apoptosis; Biocompatible Materials; Blotting, Western; Calcium Compounds; Cell Line, Tumor; Coloring Agents; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Flavonoids; Humans; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinases; Oxides; Signal Transduction; Silicates; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins | 2003 |
The PLC-PKC cascade is required for IL-1beta-dependent Erk and Akt activation: their role in proliferation.
Topics: Animals; Antigens, Differentiation; BALB 3T3 Cells; Cell Division; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Glycoproteins; Immunoblotting; Indoles; Interleukin-1; Maleimides; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neural Cell Adhesion Molecule L1; Phospholipase C gamma; Phosphorylation; Plasmids; Precipitin Tests; Protein Kinase C; Pyrrolidinones; Receptors, Immunologic; Signal Transduction; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Type C Phospholipases | 2003 |
3-OH flavone inhibition of epidermal growth factor-induced proliferaton through blocking prostaglandin E2 production.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cell Division; Colony-Forming Units Assay; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Gastrodia elata prevents rat pheochromocytoma cells from serum-deprived apoptosis: the role of the MAPK family.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Dicumarol; Drugs, Chinese Herbal; Flavonoids; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Neuroprotective Agents; PC12 Cells; Phosphorylation; Pyridines; Rats; Signal Transduction; Tetrazolium Salts; Thiazoles | 2004 |
The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurones from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways.
Topics: Androstadienes; Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavonoids; Indoles; Mitogen-Activated Protein Kinases; Neurons; Peptide Fragments; Phosphatidylinositol 3-Kinases; Potassium; Precipitin Tests; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetanus Toxin; Tetrazolium Salts; Thiazoles; Time Factors; Wortmannin | 2004 |
Role of MAPK/ERK in neurotrophin-4 potentiation of necrotic neuronal death.
Topics: Animals; Butadienes; Cell Death; Cells, Cultured; Cyclosporine; Enzyme Activation; Flavonoids; Immunosuppressive Agents; L-Lactate Dehydrogenase; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nerve Growth Factors; Neurons; Nitriles; Phosphorylation; Tetrazolium Salts; Thiazoles | 2004 |
Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.
Topics: Adipocytes; Animals; Biological Transport; Cell Line; Cells, Cultured; Fibroblasts; Flavonoids; Gene Expression Regulation; Glucose; Humans; Imidazoles; MAP Kinase Kinase Kinases; Muscle Fibers, Skeletal; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; PPAR delta; Pyridines; Thiazoles | 2005 |
Pro- and anti-inflammatory cytokines regulate the ERK pathway: implication of the timing for the activation of microglial cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Cell Death; Cells, Cultured; Cerebral Cortex; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethidium; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hippocampus; Interleukin-1; Neuroglia; Neurons; Nitrites; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Lactate Dehydrogenases; Nicotine; Phosphorylation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2006 |
Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis.
Topics: Animals; Cell Line; Cell Survival; Chromones; Flavonoids; Insulin; Methacrylates; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle Cells; Muscle Development; Muscle, Skeletal; Myogenin; Oligomycins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rotenone; Signal Transduction; Thiazoles; Uncoupling Agents | 2006 |
Neurotoxicity of cadmium on immature hippocampus and a neuroprotective role for p38 MAPK.
Topics: Animals; Animals, Newborn; Cadmium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Hippocampus; Imidazoles; In Vitro Techniques; Male; Neurotoxins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2008 |
Effect of oncostatin M on uridine diphosphate-5'-glucuronosyltransferase 1A1 through cross talk with constitutive androstane receptor.
Topics: Animals; Animals, Newborn; Blotting, Western; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Flavonoids; Glucuronosyltransferase; Hep G2 Cells; Humans; Infant, Newborn; Jaundice, Neonatal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Oncostatin M; Oximes; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiazoles | 2010 |
Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.
Topics: Animals; Butadienes; Cell Differentiation; Creatine Kinase, Mitochondrial Form; Dual Specificity Phosphatase 1; ERRalpha Estrogen-Related Receptor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Kinetics; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Muscle Development; Muscle Fibers, Skeletal; Muscle Proteins; Myoblasts, Skeletal; Myogenin; Myosin Heavy Chains; Nitriles; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Receptors, Estrogen; Ribosomal Protein S6 Kinases, 90-kDa; Sarcomeres; Thiazoles; Trans-Activators; Transcription Factors; Transduction, Genetic; Troponin I; Up-Regulation | 2011 |
S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway.
Topics: Animals; Calgranulin B; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Hep G2 Cells; Humans; Imidazoles; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Transplantation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Random Allocation; Tetrazolium Salts; Thiazoles; Xenograft Model Antitumor Assays | 2013 |
Natriuretic peptide receptor-C agonist attenuates the expression of cell cycle proteins and proliferation of vascular smooth muscle cells from spontaneously hypertensive rats: role of Gi proteins and MAPkinase/PI3kinase signaling.
Topics: Animals; Atrial Natriuretic Factor; Cell Cycle Proteins; Cell Proliferation; Cyclin D; Cyclin-Dependent Kinases; DNA; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Guanine; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Receptors, Atrial Natriuretic Factor; Retinoblastoma Protein; Thiazoles | 2013 |
Transcriptional regulation of Δ6-desaturase by peroxisome proliferative-activated receptor δ agonist in human pancreatic cancer cells: role of MEK/ERK1/2 pathway.
Topics: Cell Line, Tumor; ErbB Receptors; Fatty Acid Desaturases; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Signaling System; Pancreatic Neoplasms; PPAR delta; Protein Kinase Inhibitors; Quinazolines; RNA, Messenger; RNA, Neoplasm; Thiazoles; Tyrphostins | 2013 |
Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders.
Topics: AIDS Dementia Complex; Animals; Antineoplastic Agents; Cyclin-Dependent Kinase 5; Dasatinib; Erlotinib Hydrochloride; Flavonoids; HIV Envelope Protein gp120; In Vitro Techniques; Indoles; Lapatinib; Mice; Mice, Transgenic; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Protein Kinase Inhibitors; Purines; Pyrimidines; Pyrroles; Quinazolines; Rats; Roscovitine; Sunitinib; Thiazoles | 2014 |
Effect of PPARδ agonist on stearoyl-CoA desaturase 1 in human pancreatic cancer cells: role of MEK/ERK1/2 pathway.
Topics: Cell Line, Tumor; Flavonoids; Humans; MAP Kinase Signaling System; Pancreatic Neoplasms; PPAR delta; Stearoyl-CoA Desaturase; Thiazoles | 2015 |
Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Erlotinib Hydrochloride; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Thiazoles; TOR Serine-Threonine Kinases | 2016 |
The Role of 5-HTR6 in Mossy Fiber Sprouting: Activating Fyn and p-ERK1/2 in Pilocarpine-Induced Chronic Epileptic Rats.
Topics: Animals; Disease Models, Animal; Epilepsy; Flavonoids; GAP-43 Protein; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscarinic Agonists; Pilocarpine; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; RNA, Messenger; Serotonin Receptor Agonists; Status Epilepticus; Thiazoles; Time Factors; Tryptamines; Up-Regulation | 2017 |