Page last updated: 2024-08-21

thiazoles and pateamine a

thiazoles has been researched along with pateamine a in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	15 (40.54)	29.6817
2010's	18 (48.65)	24.3611
2020's	4 (10.81)	2.80

Authors

Authors	Studies
Buchler, IP; Cohn, ST; Cox, MM; Langenhan, JM; Messerschmidt, NB; Park, K; Romo, D; Rzasa, RM; Schmitz, WD; Shea, HA; Yang, J	1
Berridge, MV; Hood, KA; Miller, JH; Northcote, PT; West, LM	1
Buchler, I; Choi, NS; Li, S; Liu, JO; Romo, D; Shi, Z	1
Bordeleau, ME; Jankowsky, E; Lindqvist, L; Matthews, J; Northcote, P; Novac, O; Pelletier, J; Sonenberg, N; Teesdale-Spittle, P; Wojnar, JM	1
Choi, NS; Dang, Y; Liu, JO; Low, WK; Merrick, WC; Romo, D; Schneider-Poetsch, T; Shi, Z	1
Anderson, P; Dang, Y; Gorospe, M; Kaufman, R; Kedersha, N; Liu, JO; Low, WK; Romo, D	1
Clardy, J	1
Bordeleau, ME; Cencic, R; Lindqvist, L; Northcote, P; Oberer, M; Pelletier, J; Wagner, G	1
Korneeva, NL	1
Bhat, S; Dang, Y; Liu, JO; Low, WK; Romo, D	1
Choi, NS; Dang, Y; Li, S; Liu, JO; Low, WK; Ma, G; Park, K; Romo, D; Rzasa, RM; Schneider-Poetsch, T; Shea, HA; Shi, Z	1
Agoulnik, S; Boivin, R; Chen, Z; Du, H; Jiang, Y; Kuznetsov, G; Littlefield, BA; Liu, J; Marsh, J; Parent, L; Romo, D; Rudolph-Owen, L; Shie, JL; Tendyke, K; Towle, M; Twine, N; Wang, Y; Xu, Q; Zhang, H; Zhao, N	1
Dang, Y; Dietz, HC; Gehring, NH; Liu, JO; Low, WK; Romo, D; Xu, J	1
Dingledine, R; Irier, HA; Quan, Y; Yoo, J	1
Anderson, P; Dawra, N; Emara, MM; Hickman, T; Hu, GF; Ivanov, P; Kedersha, N; Tisdale, S	1
Miller, JH; Northcote, PT; Singh, AJ	1
Lindqvist, L; Pelletier, J	1
Lifland, AW; Santangelo, PJ; Zurla, C	1
Banfield, BW; Finnen, RL; Pangka, KR	1
Cammas, A; Di Marco, S; Gallouzi, IE; Hall, DT; Kovacs, EN; Lian, XJ; Ma, JF; Mazroui, R; Pelletier, J; Richardson, J	1
Cencic, R; Galicia-Vázquez, G; Pelletier, J	1
Hull, K; Kommaraju, SS; Li, J; Liu, JO; Low, WK; Romo, D; Shah-Mittal, J; Zhu, M	1
Ankri, S; Katz, S; Trebicz-Geffen, M	1
Barisé, R; Mahboubi, H; Stochaj, U	1
Carrasco, L; García-Moreno, M; González-Almela, E; Northcote, P; Pelletier, J; Sanz, MA	1
Quesne, JL; Raza, F; Waldron, JA	1
Barbry, P; Lebrigand, K; Popa, A; Waldmann, R	1
Cai, Y; Lu, C; Makala, L; Wu, D	1
Brown, SL; Cuyamendous, C; Field, JJ; Harvey, JE; Hemi Cumming, A; Miller, JH; Tao, X; Teesdale-Spittle, PH	1
Campbell-Valois, FX; Dufour, A; Sansonetti, PJ; Schnupf, P; Vonaesch, P	1
Khaperskyy, DA; Kleer, M; McCormick, C; Slaine, PD; Smith, NK	1
Cramer, Z; Di Marco, S; Gallouzi, IE; Pause, A; Pelletier, J; Sadek, J; Vazquez, GG	1
Fürstner, A; Zhuo, CX	1
Pelletier, J; Shen, L	1
Aulicino, J; Gobbooru, S; Kommaraju, SS; Li, J; Low, WK; Romo, D; Zhu, M	1
Amador, LA; Cencic, R; Itoua Maïga, R; Jankowsky, E; Naineni, SK; Pelletier, J; Putnam, AA; Rodriguez, AD	1
Cencic, R; Hull, K; Liang, J; Nagar, B; Naineni, SK; Northcote, P; Pelletier, J; Romo, D; Teesdale-Spittle, P; Zhu, M	1

Reviews

7 review(s) available for thiazoles and pateamine a

Article	Year
Total synthesis of marine natural products driven by novel structure, potent biological activity, and/or synthetic methodology. Ernst Schering Research Foundation workshop, 2000, Issue:32 Topics: Animals; Biological Products; Dinoflagellida; Epoxy Compounds; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Biology; Marine Toxins; Methods; Porifera; Sesquiterpenes; Thiazoles	2000
Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A. Methods in enzymology, 2007, Volume: 431 Topics: Animals; Bacterial Proteins; Biotin; Chromatography, Affinity; Cyclohexylamines; Drug Design; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Models, Biological; Protein Binding; Sepharose; Structure-Activity Relationship; Thiazoles	2007
Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolide. Marine drugs, 2010, Mar-31, Volume: 8, Issue:4 Topics: Animals; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Epoxy Compounds; Humans; Lactones; Macrolides; Microtubules; Neoplasms; Porifera; Pyrans; Thiazoles	2010
Inhibitors of translation initiation as cancer therapeutics. Future medicinal chemistry, 2009, Volume: 1, Issue:9 Topics: Antineoplastic Agents; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4E; Humans; Hydrazones; Macrolides; Neoplasms; Nitro Compounds; Oligonucleotides, Antisense; Protein Biosynthesis; Sterols; Thiazoles; Triterpenes	2009
Translational dysregulation in cancer: eIF4A isoforms and sequence determinants of eIF4A dependence. Biochemical Society transactions, 2015, Volume: 43, Issue:6 Topics: Epoxy Compounds; Eukaryotic Initiation Factor-4A; Gene Expression Regulation, Neoplastic; Humans; Macrolides; Molecular Targeted Therapy; Neoplasms; Protein Biosynthesis; Protein Isoforms; Sterols; Thiazoles; Triterpenes	2015
Targeting translation: eIF4E as an emerging anticancer drug target. Expert reviews in molecular medicine, 2016, Jan-18, Volume: 18 Topics: Animals; Antineoplastic Agents; Cyclin D1; Epoxy Compounds; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Macrolides; Neoplasms; Oligonucleotides, Antisense; Protein Biosynthesis; Ribavirin; RNA, Small Interfering; Signal Transduction; Sirolimus; Survivin; Thiazoles; Triterpenes; Vascular Endothelial Growth Factor A	2016
Selective targeting of the DEAD-box RNA helicase eukaryotic initiation factor (eIF) 4A by natural products. Natural product reports, 2020, 05-01, Volume: 37, Issue:5 Topics: Animals; Antineoplastic Agents; Biological Products; DEAD-box RNA Helicases; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Gene Expression Regulation; Humans; Macrolides; Molecular Targeted Therapy; Neoplasms; Protein Biosynthesis; Sterols; Thiazoles	2020

Other Studies

30 other study(ies) available for thiazoles and pateamine a

Article	Year
Induction of apoptosis by the marine sponge (Mycale) metabolites, mycalamide A and pateamine. Apoptosis : an international journal on programmed cell death, 2001, Volume: 6, Issue:3 Topics: Animals; Annexin A5; Apoptosis; Cell Survival; Coloring Agents; Cycloheximide; Cytarabine; DNA; DNA Damage; Electrophoresis, Agar Gel; Enzyme Inhibitors; Epoxy Compounds; Flow Cytometry; Inhibitory Concentration 50; Macrolides; Models, Chemical; Porifera; Protein Synthesis Inhibitors; Puromycin; Pyrans; Tetrazolium Salts; Thiazoles; Trypan Blue	2001
Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative. Journal of the American Chemical Society, 2004, Sep-01, Volume: 126, Issue:34 Topics: Antineoplastic Agents; Binding Sites; Drug Design; Epoxy Compounds; Genes, Reporter; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Macrolides; Receptors, Antigen, T-Cell; Thiazoles	2004
Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proceedings of the National Academy of Sciences of the United States of America, 2005, Jul-26, Volume: 102, Issue:30 Topics: Animals; Chromatography, Agarose; Dose-Response Relationship, Drug; Epoxy Compounds; Escherichia coli; Eukaryotic Initiation Factor-4A; Macrolides; Mice; Protein Biosynthesis; Recombinant Proteins; Ribosomes; RNA, Messenger; Thiazoles	2005
Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Molecular cell, 2005, Dec-09, Volume: 20, Issue:5 Topics: Epoxy Compounds; Eukaryotic Cells; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4G; Eukaryotic Initiation Factors; HeLa Cells; Humans; In Vitro Techniques; Macrolides; Molecular Structure; Protein Biosynthesis; Thiazoles	2005
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. The Journal of biological chemistry, 2006, Oct-27, Volume: 281, Issue:43 Topics: Animals; Arsenites; Biological Products; Biomarkers; Cell Line, Tumor; Cytoplasmic Granules; Dose-Response Relationship, Drug; Epoxy Compounds; Eukaryotic Initiation Factor-2; Fibroblasts; Fluorescent Antibody Technique, Direct; HeLa Cells; Humans; Macrolides; Mice; Osteosarcoma; Oxidative Stress; RNA, Messenger; Thiazoles; Time Factors	2006
Stopping trouble before it starts. ACS chemical biology, 2006, Feb-17, Volume: 1, Issue:1 Topics: Antineoplastic Agents; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Macrolides; Models, Genetic; Models, Molecular; Protein Biosynthesis; RNA, Messenger; Thiazoles	2006
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation. Chemistry & biology, 2006, Volume: 13, Issue:12 Topics: Dimerization; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4G; Humans; Jurkat Cells; Macrolides; Multiprotein Complexes; Protein Binding; Protein Biosynthesis; RNA; Thiazoles	2006
Translational dysregulation by Pateamine A. Chemistry & biology, 2007, Volume: 14, Issue:1 Topics: Antineoplastic Agents; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Macrolides; Protein Binding; Protein Biosynthesis; RNA-Binding Proteins; RNA, Messenger; Thiazoles	2007
Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. Chemistry & biology, 2007, Volume: 14, Issue:6 Topics: Adenosine Triphosphatases; Catalytic Domain; Electrophoresis, Polyacrylamide Gel; Epoxy Compounds; Escherichia coli; Eukaryotic Initiation Factor-4A; Macrolides; Protein Binding; Protein Biosynthesis; Protein Conformation; Recombinant Proteins; Ribosomes; RNA, Messenger; Substrate Specificity; Thiazoles	2007
Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A. Molecular cancer therapeutics, 2009, Volume: 8, Issue:5 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epoxy Compounds; Female; Humans; Macrolides; Mice; Mice, Nude; Mice, SCID; Neoplasms; Thiazoles; Xenograft Model Antitumor Assays	2009
Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII. The Journal of biological chemistry, 2009, Aug-28, Volume: 284, Issue:35 Topics: Biological Products; Cell Line; Codon, Nonsense; Down-Regulation; Epoxy Compounds; Eukaryotic Initiation Factors; Humans; Macrolides; Peptide Chain Initiation, Translational; Protein Binding; RNA Stability; RNA, Messenger; Thiazoles	2009
Control of glutamate receptor 2 (GluR2) translational initiation by its alternative 3' untranslated regions. Molecular pharmacology, 2009, Volume: 76, Issue:6 Topics: 3' Untranslated Regions; 5' Untranslated Regions; Aminoglycosides; Animals; Anisomycin; Cycloheximide; Epoxy Compounds; Gene Expression Regulation; Macrolides; Peptide Chain Initiation, Translational; Protein Biosynthesis; Protein Synthesis Inhibitors; Rabbits; Receptors, AMPA; Reticulocytes; RNA, Messenger; Thiazoles	2009
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. The Journal of biological chemistry, 2010, Apr-02, Volume: 285, Issue:14 Topics: Arsenites; Blotting, Western; Bone Neoplasms; Carrier Proteins; Cells, Cultured; Cytoplasmic Granules; Enzyme Inhibitors; Epoxy Compounds; Eukaryotic Initiation Factor-2; Fluorescent Antibody Technique; Humans; Macrolides; Osteosarcoma; Oxidative Stress; Phosphorylation; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease, Pancreatic; RNA, Messenger; RNA, Small Interfering; RNA, Transfer; Teratogens; Thiazoles; Tumor Cells, Cultured	2010
Characterizing mRNA interactions with RNA granules during translation initiation inhibition. PloS one, 2011, May-05, Volume: 6, Issue:5 Topics: Actins; Arsenites; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cycloheximide; Cytoplasmic Granules; Epoxy Compounds; Exosomes; Humans; Macrolides; Microtubule-Organizing Center; Molecular Probes; Nocodazole; Peptide Chain Initiation, Translational; Poly A; Puromycin; RNA Transport; RNA, Messenger; Sodium Compounds; Stress, Physiological; Thiazoles	2011
Herpes simplex virus 2 infection impacts stress granule accumulation. Journal of virology, 2012, Volume: 86, Issue:15 Topics: Adaptor Proteins, Signal Transducing; Animals; Carrier Proteins; Chlorocebus aethiops; Cytoplasmic Granules; DNA Helicases; DNA Replication; DNA-Binding Proteins; DNA, Viral; Epoxy Compounds; Eukaryotic Initiation Factor-2; HeLa Cells; Herpes Genitalis; Herpesvirus 2, Human; Humans; Macrolides; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Poly(A)-Binding Proteins; RNA Helicases; RNA Recognition Motif Proteins; RNA-Binding Proteins; T-Cell Intracellular Antigen-1; Thiazoles; Vero Cells; Virus Replication	2012
The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice. Nature communications, 2012, Jun-12, Volume: 3 Topics: Animals; Apoptosis; Blotting, Northern; Cachexia; Cell Line; Epoxy Compounds; Immunoblotting; Immunoprecipitation; In Situ Hybridization; Interleukin-6; Macrolides; Male; Mice; Mice, Inbred BALB C; Muscular Atrophy; Nitrogen Oxides; Thiazoles	2012
Inhibitors of translation targeting eukaryotic translation initiation factor 4A. Methods in enzymology, 2012, Volume: 511 Topics: Animals; Anthracenes; Benzofurans; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Perylene; Protein Kinase Inhibitors; Sterols; Thiazoles	2012
Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Antineoplastic Agents; Biological Products; Cell Proliferation; Epoxy Compounds; Eukaryotic Initiation Factors; Humans; Macrolides; Peptide Chain Initiation, Translational; Thiazoles	2014
Stress granule formation in Entamoeba histolytica: cross-talk between EhMLBP, EhRLE3 reverse transcriptase and polyubiquitinated proteins. Cellular microbiology, 2014, Volume: 16, Issue:8 Topics: Arsenates; Cytoplasmic Granules; DNA Methylation; DNA, Protozoan; Dysentery, Amebic; Entamoeba histolytica; Entamoebiasis; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Heat-Shock Response; Long Interspersed Nucleotide Elements; Macrolides; Protein Synthesis Inhibitors; Protozoan Proteins; Puromycin; RNA-Directed DNA Polymerase; Thiazoles; Ubiquitinated Proteins	2014
5'-AMP-activated protein kinase alpha regulates stress granule biogenesis. Biochimica et biophysica acta, 2015, Volume: 1853, Issue:7 Topics: AMP-Activated Protein Kinases; Carrier Proteins; Cell Survival; Cytoplasmic Granules; DNA Helicases; Energy Metabolism; Enzyme Activation; Epoxy Compounds; Gene Knockdown Techniques; HeLa Cells; Humans; Isoenzymes; Macrolides; Models, Biological; Mutant Proteins; Oxidative Stress; Poly-ADP-Ribose Binding Proteins; Protein Binding; RNA Helicases; RNA Recognition Motif Proteins; Stress, Physiological; Thiazoles	2015
Differential action of pateamine A on translation of genomic and subgenomic mRNAs from Sindbis virus. Virology, 2015, Volume: 484 Topics: Animals; Cell Line; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Macrolides; Protein Biosynthesis; Protein Synthesis Inhibitors; RNA, Messenger; RNA, Viral; Sindbis Virus; Thiazoles; Time Factors; Virus Replication	2015
Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells. BMC genomics, 2016, Jan-14, Volume: 17 Topics: 5' Untranslated Regions; Animals; Epoxy Compounds; Gene Expression Regulation; Macrolides; Mice; Mouse Embryonic Stem Cells; Open Reading Frames; Protein Biosynthesis; Ribosomes; RNA, Long Noncoding; Thiazoles	2016
Synthesis of a simplified triazole analogue of pateamine A. Organic & biomolecular chemistry, 2016, Jun-14, Volume: 14, Issue:22 Topics: Antineoplastic Agents; Azides; Catalysis; Chemistry Techniques, Synthetic; Copper; Epoxy Compounds; Macrolides; Thiazoles; Triazoles	2016
Shigella flexneri modulates stress granule composition and inhibits stress granule aggregation. Cellular microbiology, 2016, Volume: 18, Issue:7 Topics: Actins; Carrier Proteins; Cytoplasmic Granules; DNA Helicases; Dysentery, Bacillary; Epoxy Compounds; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-3; Eukaryotic Initiation Factors; Golgi Apparatus; HeLa Cells; Host-Pathogen Interactions; Humans; Macrolides; Microtubules; Mutation; Phosphorylation; Poly-ADP-Ribose Binding Proteins; RNA Helicases; RNA Recognition Motif Proteins; Shigella flexneri; Stress, Physiological; Thiazoles	2016
Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication. Viruses, 2017, 12-18, Volume: 9, Issue:12 Topics: A549 Cells; Antiviral Agents; Enzyme Inhibitors; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Influenza A virus; Macrolides; Protein Biosynthesis; Thiazoles; Triterpenes; Virus Replication	2017
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways. Scientific reports, 2018, 05-30, Volume: 8, Issue:1 Topics: Allosteric Regulation; Animals; Cell Line; Cytokines; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Interleukin-6; Macrolides; Mice; Muscle Fibers, Skeletal; Muscular Atrophy; Nitric Oxide Synthase Type II; STAT3 Transcription Factor; Sterols; Thiazoles	2018
Catalysis-Based Total Syntheses of Pateamine A and DMDA-Pat A. Journal of the American Chemical Society, 2018, 08-22, Volume: 140, Issue:33 Topics: Animals; Catalysis; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Heterografts; Humans; Macrolides; Thiazoles	2018
Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA). Biochemistry and cell biology = Biochimie et biologie cellulaire, 2020, Volume: 98, Issue:4 Topics: Adenosine Triphosphatases; Biological Products; Cell Line; Cell Proliferation; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Neoplasms; Recombinant Proteins; RNA, Messenger; Thiazoles	2020
A comparative study of small molecules targeting eIF4A. RNA (New York, N.Y.), 2020, Volume: 26, Issue:5 Topics: Antineoplastic Agents; Benzofurans; Cell Proliferation; Cell Survival; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4F; Humans; Macrolides; Neoplasms; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Small Molecule Libraries; Sterols; Thiazoles; TOR Serine-Threonine Kinases	2020
Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A. Cell chemical biology, 2021, 06-17, Volume: 28, Issue:6 Topics: Cell Line; Crystallography, X-Ray; Epoxy Compounds; Eukaryotic Initiation Factor-4A; Humans; Macrolides; Models, Molecular; Molecular Conformation; RNA; Thiazoles	2021