thiazoles has been researched along with ovalbumin in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.51) | 18.7374 |
| 1990's | 16 (34.04) | 18.2507 |
| 2000's | 18 (38.30) | 29.6817 |
| 2010's | 8 (17.02) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bernat, A; Herbert, JM; Laplace, MC; Maffrand, JP; Salel, V | 1 |
| Lewis, SA; Raeburn, D; Underwood, SL | 1 |
| Imanishi, N; Morooka, S; Uchida, M | 1 |
| Herbert, JM; Lespy, L; Maffrand, JP | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T | 1 |
| Cirino, M; Desquand, S; Hadvary, P; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Vargaftig, BB | 1 |
| Kado, Y; Kumada, S; Takashima, T | 1 |
| Edwards, K; Jackson, H; Jones, AR | 1 |
| Bogulska, M; Katzenellenbogen, E; Lugowski, C; Romanowska, E | 1 |
| Arima, M; Makino, S; Yukawa, T | 1 |
| Barnes, PJ; Chung, KF; Elwood, W; Giembycz, MA; Sun, J | 1 |
| Asakura, K; Narita, S | 2 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Renzetti, LM; Wasserman, MA; Welton, AF | 1 |
| Meurs, H; Olymulder, CG; Santing, RE; Van der Molen, K; Zaagsma, J | 1 |
| Fujii, T; Hiroi, J; Manabe, T; Matsuda, H; Matsuo, M; Shigenaga, S | 1 |
| Bernat, A; Herbert, JM; Tibiriça, E | 1 |
| Bae, SJ; Hakugawa, J; Katayama, I; Tanaka, Y; Vinuesa, MA | 1 |
| Arakida, Y; Honda, K; Miyata, K; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Arakida, Y; Morio, H; Ohga, K; Okada, Y; Suwa, K; Yamada, T; Yokota, M | 1 |
| Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K | 1 |
| Diez-Ortego, I; Egido, J; Herrero-Beaumont, G; Largo, R; López-Armada, MJ; Palacios, I; Sánchez-Pernaute, O | 1 |
| Angeli, V; Capron, M; Hammad, H; Lambrecht, BN; Staels, B; Trottein, F | 1 |
| Choi, IW; Im, MJ; Kim, UH; Lee, HK; Lee, KS; Lee, YC; Lim, JS; Park, HS; Park, KH; Park, SJ | 1 |
| Azakami, H; Kato, A; Mukai, A | 1 |
| Jin, SM; Kim, CY; Kim, SR; Kim, UH; Lee, KS; Lee, YC; Min, KH; Park, HS; Park, KH; Park, SJ | 1 |
| Jin, SM; Kim, SR; Lee, KS; Lee, YC; Li, L; Min, KH; Park, HS; Park, SJ | 1 |
| Gerrard, JA; Mackintosh, SH; Pearce, FG | 1 |
| Hiyama, Y; Ishimura, M; Kataoka, S; Kurokawa, S; Maeda, T; Morizumi, K; Suda, M | 1 |
| Estephan, R; Kano, S; Levi, R; Mackins, CJ; Reid, AC; Salazar-Rodriguez, M; Silver, RB; Tyler, E; Veerappan, A | 1 |
| Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E | 1 |
| Jahangeer, S; Kotani, Y; Kuramoto, E; Nakamura, S; Nishimura, Y; Nishiuma, T; Okada, T | 1 |
| Ishimura, M; Kohno, S; Kurokawa, S; Mizutani, N; Nabe, T; Suda, M | 1 |
| Blake, SJ; Brown, MP; Diener, KR; Fraser, CK; Hayball, JD; Hughes, TP; Lyons, AB | 1 |
| Baur, F; Fozard, JR; Trifilieff, A | 1 |
| Ishimura, M; Kurokawa, S; Nagai, H; Nakamura, T; Okuda, T; Suda, M; Takahashi, Y; Tanaka, H; Tokuoka, S | 1 |
| Hu, L; Li, J; Liu, J; Ma, L; Sun, L; Yu, Y | 1 |
| Brown, MP; Diener, KR; Fraser, CK; Guerin, LR; Hayball, JD; Hughes, TP; Lousberg, EL | 1 |
| Iram, A; Naeem, A | 1 |
| Amani, S; Naeem, A | 1 |
| Chen, B; Dunford, PJ; Greenspan, AJ; Karlsson, L; La, D; Thurmond, RL; Ward, P; Xu, XL | 1 |
| Dash, RP; Nivsarkar, M; Pandya, AN; Patil, D; Thakur, SK; Vasu, KK; Venkatesh, P | 1 |
| Gao, Y; Guo, S; Shi, Y; Yang, L; Ye, L; Zhang, T; Zhao, T; Zheng, Y; Zhou, L | 1 |
| Chen, P; Dou, J; Li, J; Yang, J; Yang, L; Zhao, C; Zhao, S | 1 |
| Björhall, K; Bold, P; Börjesson, U; Brűlls, M; Carlsson, J; Chang, HA; Chen, Y; Eriksson, A; Fihn, BM; Fransson, R; Fredlund, L; Ge, H; Huang, H; Karabelas, K; Lamm Bergström, E; Lever, S; Lindmark, H; Mogemark, M; Nikitidis, A; Öster, L; Palmgren, AP; Pemberton, N; Perry, MWD; Petersen, J; Rodrigo Blomqvist, M; Smith, RW; Thomas, MJ; Tyrchan, C; Ullah, V; Wennberg, T; Westin Eriksson, A; Yang, W; Zhao, S | 1 |
1 trial(s) available for thiazoles and ovalbumin
| Article | Year |
|---|---|
Clinical and preclinical characterization of the histamine H(4) receptor antagonist JNJ-39758979.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Cell Shape; Dermatitis, Contact; Double-Blind Method; Eosinophils; Female; Humans; Isothiocyanates; Macaca fascicularis; Male; Ovalbumin; Pyrimidines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Thiazoles | 2014 |
46 other study(ies) available for thiazoles and ovalbumin
| Article | Year |
|---|---|
Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigen.
Topics: Allergens; Animals; Antigens; Edema; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Rabbits; Skin Diseases; Thiazoles | 1992 |
RP 59227, a novel PAF receptor antagonist: effects in guinea pig models of airway hyperreactivity.
Topics: Animals; Antigens; Azepines; Bronchial Hyperreactivity; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Guinea Pigs; Male; Ovalbumin; Platelet Activating Factor; Pyridines; Thiazoles; Triazoles | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines | 1992 |
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
Interference of the Paf antagonist Ro 19-3704 with Paf and antigen-induced bronchoconstriction in the guinea-pig.
Topics: Aerosols; Animals; Blood Cell Count; Bronchodilator Agents; Female; Glyceryl Ethers; Guinea Pigs; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Alveoli; Thiazoles | 1988 |
Pharmacological investigations of benzothiazoline derivatives.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Benzyl Compounds; Body Temperature; Carrageenan; Edema; Formaldehyde; Guinea Pigs; Lethal Dose 50; Male; Methylamines; Ovalbumin; Oxyphenbutazone; Phenylbutazone; Piperazines; Pyrazoles; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiazoles | 1972 |
Studies with alkylating esters. II. A chemical interpretation through metabolic studies of the antifertility effects of ethylene dimethanesulphonate and ethylene dibromide.
Topics: Adipose Tissue; Alkylating Agents; Animals; Bile; Bromine; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gas; Chromatography, Paper; Cysteine; Esters; Ethanol; Fertility; Hydrocarbons, Halogenated; Intestine, Small; Kidney; Liver; Male; Mice; Ovalbumin; Rats; Spermatozoa; Sulfides; Sulfonic Acids; Sulfoxides; Sulfur Isotopes; Thiazoles | 1970 |
Interaction of Wratizolin with serum albumins and its antiproteolytic activity.
Topics: Animals; Cattle; Chromatography, Gel; Chymotrypsin; Dansyl Compounds; Horses; Humans; In Vitro Techniques; Indomethacin; Ovalbumin; Protease Inhibitors; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Thiazoles; Trypsin Inhibitors; Tryptophan; Uric Acid | 1983 |
Effect of YM264 on the airway hyperresponsiveness and the late asthmatic response in a guinea pig model of asthma.
Topics: Aerosols; Airway Resistance; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; Immunization; Male; Ovalbumin; Piperazines; Platelet Activating Factor; Random Allocation; Statistics, Nonparametric; Thiazoles; Thiazolidines; Time Factors; Trachea | 1995 |
Inhibition of allergen-induced lung eosinophilia by type-III and combined type III- and IV-selective phosphodiesterase inhibitors in brown-Norway rats.
Topics: Administration, Inhalation; Aerosols; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Eosinophils; Female; Injections, Intraperitoneal; Neutrophils; Ovalbumin; Phosphodiesterase Inhibitors; Pulmonary Eosinophilia; Pyrrolidinones; Rats; Rats, Inbred BN; Rolipram; Thiazoles | 1995 |
The role of platelet-activating factor on histamine hypersensitivity in nasal allergy in guinea pig models.
Topics: Allergens; Animals; Guinea Pigs; Histamine Release; Hypersensitivity; Male; Ovalbumin; Platelet Activating Factor; Thiazoles; Thiazolidines | 1993 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Synergism exhibited by LTD4 and PAF receptor antagonists in decreasing antigen-induced airway microvascular leakage.
Topics: Animals; Bronchi; Bronchodilator Agents; Drug Synergism; Guinea Pigs; Immunization; Leukotriene D4; Lung; Male; Microcirculation; Ovalbumin; Phenanthridines; Platelet Membrane Glycoproteins; Pulmonary Circulation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; SRS-A; Thiazoles; Trachea; Triazines | 1995 |
Phosphodiesterase inhibitors reduce bronchial hyperreactivity and airway inflammation in unrestrained guinea pigs.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Inhalation; Analysis of Variance; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Eosinophils; Guinea Pigs; Histamine; Hypersensitivity; Inflammation; Injections, Intraperitoneal; Isoenzymes; Macrophages; Male; Neutrophils; Ovalbumin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Specific Pathogen-Free Organisms; Theophylline; Thiazoles | 1995 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Synthesis and pharmacological properties of N-[4-[4-(1H-indol-3-yl) piperidinoalkyl]-2-thiazolyl]alkanesulfonamides as novel antiallergic agents.
Topics: Anaphylaxis; Animals; Guinea Pigs; Hypersensitivity; Indoles; Male; Mice; Mice, Inbred ICR; Ovalbumin; Rabbits; Structure-Activity Relationship; Sulfonamides; Thiazoles | 1993 |
Effect of SR 27417, a novel PAF antagonist on antigen-induced hypotension in the rat.
Topics: Animals; Antigens; Hypotension; Male; Ovalbumin; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
[The inhibitory effect of LTB4 antagonist on eosinophil infiltration in cutaneous and gut late phase response in BALB/C mice sensitized with ovalubumin (OVA)].
Topics: Animals; Cell Movement; Dermatitis, Atopic; Eosinophils; Female; Immunization; Immunosuppressive Agents; Intestines; Leukotriene B4; Mice; Mice, Inbred BALB C; Ovalbumin; Phenylpropionates; Platelet Activating Factor; Skin; Thiazoles | 1997 |
Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs.
Topics: Acetylcholine; Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Benzoquinones; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chromones; Dose-Response Relationship, Immunologic; Guinea Pigs; Heptanoic Acids; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Ozone; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles | 2000 |
Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs.
Topics: Administration, Oral; Airway Resistance; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Asthma; Benzoquinones; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Heptanoic Acids; Indomethacin; Leukotriene Antagonists; Leukotriene B4; Leukotriene C4; Leukotriene E4; Lipid Metabolism; Lung; Male; Membrane Proteins; Ovalbumin; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Thromboxane B2; Time Factors | 2000 |
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinetics; Leukotriene Antagonists; Leukotrienes; Male; Membrane Proteins; Ovalbumin; Pulmonary Eosinophilia; Receptors, Leukotriene; Thiazoles | 2002 |
Modulation of cell recruitment by anti-inflammatory agents in antigen-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemokine CCL2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Gene Expression Regulation; Interleukin-8; Leukocytes; Meloxicam; Neutrophil Infiltration; Ovalbumin; Rabbits; Thiazines; Thiazoles | 2002 |
Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response.
Topics: Animals; Cell Migration Inhibition; Cell Movement; Cells, Cultured; Cytokines; Dendritic Cells; Dermatitis, Contact; Epidermis; Female; Fluorescein-5-isothiocyanate; Haptens; Immunosuppressive Agents; Langerhans Cells; Lung; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Ovalbumin; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thorax; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2003 |
Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchitis; Cell Adhesion Molecules; Chemokines; Disease Models, Animal; Eosinophil Cationic Protein; Interleukins; Lung; Mice; NF-kappa B; Ovalbumin; Prodrugs; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines | 2004 |
Role of amyloid type cross beta-structure in the formation of soluble aggregate and gel in heat-induced ovalbumin.
Topics: Amyloid; Benzothiazoles; Fluorescent Dyes; Gels; Hot Temperature; Hydrogen-Ion Concentration; Ovalbumin; Protein Denaturation; Protein Structure, Secondary; Spectrometry, Fluorescence; Thiazoles | 2005 |
A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma.
Topics: Animals; Asthma; Capillary Permeability; Female; Mice; Mice, Inbred BALB C; Ovalbumin; Phosphatidylinositol 3-Kinases; Phosphorylation; Prodrugs; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines; Thioctic Acid; Vascular Endothelial Growth Factor A | 2005 |
An antioxidant modulates expression of receptor activator of NF-kappaB in asthma.
Topics: Animals; Antioxidants; Asthma; Blotting, Western; Bronchoalveolar Lavage Fluid; Capillary Permeability; Female; Gene Expression; Glycoproteins; Immunohistochemistry; Mice; Mice, Inbred C57BL; Osteoprotegerin; Ovalbumin; Phosphorylation; Prodrugs; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidines; Vascular Endothelial Growth Factor A | 2006 |
Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing.
Topics: Amyloid; Benzothiazoles; Circular Dichroism; Food Handling; Ovalbumin; Protein Denaturation; Proteins; Serum Albumin, Bovine; Thiazoles; X-Ray Diffraction | 2007 |
Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Administration, Inhalation; Administration, Oral; Airway Obstruction; Animals; Anti-Asthmatic Agents; Benzoates; Benzoquinones; Bronchoconstriction; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Leukotriene Antagonists; Leukotriene D4; Lung; Male; Membrane Proteins; Ovalbumin; Prostaglandin Antagonists; Quinolines; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Respiratory Hypersensitivity; Sulfides; Thiazoles; Time Factors | 2008 |
Immediate hypersensitivity elicits renin release from cardiac mast cells.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; beta-N-Acetylhexosaminidases; Cell Degranulation; Cromolyn Sodium; Guinea Pigs; Hypersensitivity, Immediate; In Vitro Techniques; Male; Mast Cells; Myocardium; Norepinephrine; Ovalbumin; Oxamic Acid; Pyridines; Renin; Thiazoles | 2008 |
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2 | 2008 |
Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.
Topics: Administration, Inhalation; Aniline Compounds; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemokines, CC; Disease Models, Animal; Enzyme Inhibitors; Goblet Cells; Humans; Hyperplasia; Interleukins; Lysophospholipids; Mice; Mice, Inbred C57BL; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Respiratory Mucosa; Sphingosine; Thiazoles | 2008 |
Effects of KP-496, a novel dual antagonist of leukotriene D(4) and thromboxane A (2) receptors on nasal blockage in guinea pig models of allergic rhinitis.
Topics: Airway Resistance; Animals; Area Under Curve; Benzoates; Disease Models, Animal; Guinea Pigs; Humans; Leukotriene Antagonists; Male; Nasal Mucosa; Nasal Obstruction; Ovalbumin; Pollen; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis, Allergic, Perennial; Sneezing; Thiazoles | 2008 |
Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo.
Topics: Animals; Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Dasatinib; Fowlpox virus; Immunity, Cellular; Immunization; Killer Cells, Natural; Mice; Mice, Transgenic; Ovalbumin; Protein Kinase Inhibitors; Pyrimidines; Recombinant Proteins; Thiazoles; Transduction, Genetic | 2009 |
Role of sphingosine-1-phosphate (S1P) and the S1P(2) receptor in allergen-induced, mast cell-dependent contraction of rat lung parenchymal strips.
Topics: Acetates; Adenosine; Allergens; Animals; Bronchoconstriction; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Subcutaneous; Leukotriene Antagonists; Lung; Lysophospholipids; Male; Mast Cells; Methysergide; Ovalbumin; Phosphotransferases (Alcohol Group Acceptor); Pyrazoles; Pyridines; Quinolines; Rats; Rats, Inbred BN; Receptors, Lysosphingolipid; Serotonin; Serotonin Antagonists; Signal Transduction; Sphingosine; Sulfides; Thiazoles | 2009 |
The effects of inhaled KP-496, a novel dual antagonist for cysteinyl leukotriene receptor and thromboxane A(2) receptor, on allergic asthmatic responses in guinea pigs.
Topics: Acetylcholine; Administration, Inhalation; Animals; Anti-Asthmatic Agents; Asthma; Benzoates; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Guinea Pigs; Lung; Male; Ovalbumin; Pneumonia; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Thiazoles | 2009 |
Investigation of the immunosuppressive activity of Physalin H on T lymphocytes.
Topics: Animals; Blotting, Western; Cell Proliferation; Coloring Agents; Concanavalin A; Dinitrofluorobenzene; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heme Oxygenase-1; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppressive Agents; Indicators and Reagents; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Ovalbumin; Reverse Transcriptase Polymerase Chain Reaction; Secosteroids; Spleen; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2010 |
Dasatinib alters the metastatic phenotype of B16-OVA melanoma in vivo.
Topics: Animals; Cell Line, Tumor; Dasatinib; Dose-Response Relationship, Drug; Fowlpox virus; Humans; Immunotherapy; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Ovalbumin; Protein Kinase Inhibitors; Pyrimidines; Thiazoles; Time Factors | 2010 |
Existence of different structural intermediates and aggregates on the folding pathway of ovalbumin.
Topics: Anilino Naphthalenesulfonates; Animals; Benzothiazoles; Dose-Response Relationship, Drug; Glucose; Glycation End Products, Advanced; Guanidine; Ovalbumin; Protein Denaturation; Protein Folding; Spectrum Analysis; Thiazoles; Time Factors | 2012 |
Deciphering structural intermediates and genotoxic fibrillar aggregates of albumins: a molecular mechanism underlying for degenerative diseases.
Topics: Acetonitriles; Albumins; Benzothiazoles; Circular Dichroism; Congo Red; Humans; Lymphocytes; Microscopy, Electron, Scanning; Neurodegenerative Diseases; Ovalbumin; Protein Structure, Secondary; Sodium Chloride; Spectroscopy, Fourier Transform Infrared; Thiazoles; X-Ray Diffraction | 2013 |
Implication of novel thiazolo-thiophene derivative (MCD-KV-10) for management of asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Cytokines; Guinea Pigs; Histamine; Lipoxygenases; Lung; Male; Mast Cells; Molecular Structure; Ovalbumin; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Receptor, Adenosine A3; Thiazoles; Thiophenes | 2015 |
Exposure to PM
Topics: Animals; Asthma; Cholesterol, HDL; Cholesterol, LDL; Diamines; Disease Models, Animal; Dyslipidemias; Female; Gene Expression; Lipid Metabolism; Male; Ovalbumin; Particulate Matter; Rats; Rats, Wistar; Signal Transduction; Thiazoles; Transcription Factor HES-1; Triglycerides | 2019 |
Inhibitor of γ-secretase alleviates middle ear inflammation by regulating Th2 response in OVA-mediated allergic OME in vivo.
Topics: Allergens; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents; Cytokines; Diamines; GATA3 Transcription Factor; Jagged-1 Protein; Male; Otitis Media; Ovalbumin; Rats, Sprague-Dawley; Th2 Cells; Thiazoles; Transcription Factor HES-1 | 2019 |
Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treatment of Asthma.
Topics: Animals; Asthma; Class I Phosphatidylinositol 3-Kinases; Class Ib Phosphatidylinositol 3-Kinase; Crystallography, X-Ray; Humans; Leukocytes, Mononuclear; Male; Molecular Structure; Ovalbumin; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Kinase Inhibitors; Rats, Inbred BN; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2021 |