Page last updated: 2024-08-21

thiazoles and oridonin

thiazoles has been researched along with oridonin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, SS; Heber, D; Ikezoe, T; Koeffler, HP; Taguchi, H; Tong, XJ1
Chen, G; Wang, H; Xie, L; Zhang, R; Zhu, Y1
Ding, Y; Hua, W; Liu, J; Ran, Q; Shen, M; Wang, L; Wang, Z; Wu, X; Xu, J; Yang, J; Yuan, S; Zhang, L1
Chen, H; Chu, L; Ding, C; Liu, H; Shen, Q; Wild, C; Yang, Z; Zhang, Y; Zhou, J1
Chen, H; Cummins, CB; Ding, Y; Hughes, BD; Radhakrishnan, RS; Wang, X; Xu, J; Zhou, J1
Chen, C; Chen, P; Dai, L; Gong, Y; Jia, D; Jin, Z; Liu, D; Lou, J; Niu, D; Qi, X; Shen, X; Sun, Q; Zhang, B; Zhang, X; Zhao, L1

Other Studies

6 other study(ies) available for thiazoles and oridonin

ArticleYear
Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells.
    International journal of oncology, 2003, Volume: 23, Issue:4

    Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Humans; Neoplasms; Oncogene Proteins, Viral; Repressor Proteins; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Tumor Suppressor Protein p53

2003
Effects of oridonin on proliferation of HT29 human colon carcinoma cell lines both in vitro and in vivo in mice.
    Die Pharmazie, 2007, Volume: 62, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Diterpenes; Diterpenes, Kaurane; Female; HT29 Cells; Humans; Indicators and Reagents; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles

2007
Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates.
    Bioorganic & medicinal chemistry letters, 2008, Aug-15, Volume: 18, Issue:16

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Diterpenes, Kaurane; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; HL-60 Cells; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles

2008
Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility.
    Journal of medicinal chemistry, 2013, Jun-27, Volume: 56, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Diterpenes, Kaurane; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Nitrogen; Solubility; Thiazoles; Water; Xenograft Model Antitumor Assays

2013
Antifibrosis Effect of Novel Oridonin Analog CYD0618 Via Suppression of the NF-κB Pathway.
    The Journal of surgical research, 2018, Volume: 232

    Topics: Animals; Apoptosis; Cells, Cultured; Collagen Type I; Diterpenes, Kaurane; Hepatic Stellate Cells; Humans; Liver Cirrhosis; NF-kappa B; Nitriles; Rats; Signal Transduction; Sulfones; Thiazoles

2018
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3.
    The Journal of biological chemistry, 2019, 11-15, Volume: 294, Issue:46

    Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Cell Line, Tumor; Diterpenes, Kaurane; Female; Humans; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Ovarian Neoplasms; STAT3 Transcription Factor; Thiazoles

2019