thiazoles has been researched along with oligonucleotides in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.96) | 18.7374 |
| 1990's | 2 (3.92) | 18.2507 |
| 2000's | 32 (62.75) | 29.6817 |
| 2010's | 14 (27.45) | 24.3611 |
| 2020's | 2 (3.92) | 2.80 |
| Authors | Studies |
|---|---|
| Cramer, F; Freist, W; Maelicke, A; Sprinz, M | 1 |
| Hansen, LF; Jacobsen, JP; Jensen, LK | 1 |
| Dignam, JC; Fong, GW; George, ST; Gray, SH; Jacob-Samuel, B; Li, L; Ma, MY | 1 |
| Asano, T; Fujishima, M; Iino, K; Iwase, M; Sonoki, K; Wakisaka, M; Yoshinari, M | 1 |
| Brabec, V; Farrell, N; Kasparkova, J; Neplechova, K | 1 |
| Dubey, IY; Kostenko, AM; Yarmoluk, SM | 1 |
| Bunt, RC; Hoehn, ST; Junker, HD; Stubbe, J; Turner, CJ | 1 |
| Elder, JH; Le, VD; Lin, YC; Mak, CC; Wong, CH | 1 |
| Breydo, L; Dannaldson, J; Gates, KS; Mitra, K; Zang, H | 1 |
| Asseline, U; Melvin, T; Privat, E; Vigny, P | 1 |
| Andera, L; Cermák, L; Horejsí, V; Pintzas, A; Símová, S | 1 |
| Farquar, HD; Fronczek, FR; Hammer, RP; Miller, TJ; Saurage, AS; Sheybani, A; Tallini, CE | 1 |
| Asseline, U; Melvin, T; Mérola, F; Privat, E; Prodhomme, S; Schweizer, G; Vigny, P | 1 |
| Iida, KT; Kawakami, Y; Okuda, Y; Shimano, H; Sone, H; Suzuki, H; Toyoshima, H; Yamada, N | 1 |
| Boyanapalli, M; Dawson, MI; Fontana, JA; Hatfield, JS; Majumdar, AP; Mohammad, RM; Reichert, U; Rishi, AK; Wali, A; Yu, Y; Zhang, L | 1 |
| Höti, N; Ma, J; Tabassum, S; Wang, Y; Wu, M | 1 |
| Gates, KS; Zang, H | 1 |
| Basak, G; Drela, N; Golab, J; Jakóbisiak, M; Jakubowska, AB; Jalili, A; Lasek, W; Mackiewicz, A; Nowis, D; Sasor, A; Socha, K; Stoksik, M; Switaj, T; Wysocki, PJ | 1 |
| Cai, M; Yu, X | 1 |
| Bi, F; Fan, D; Liu, N; Pan, Y; Shi, Y; Sun, L; Xue, Y; Yao, X; Zheng, Y | 1 |
| Barvaux, VA; Gillum, AM; Lorigan, P; Margison, GP; McElhinney, RS; McMurry, TB; Ranson, M | 1 |
| Defrancq, E; Dumy, P; Villien, M | 1 |
| Krull, UJ; Wang, X | 1 |
| Baskakov, IV; Makarava, N; Parfenov, A | 1 |
| Hoagland, EM; Hoagland, MS; Swanson, HI | 1 |
| Choi, DY; Kang, KW; Kim, MR; Kim, YG; Lee, JY; Woo, ER | 1 |
| Dervan, PB; Fechter, EJ; Olenyuk, B | 1 |
| Kong, SK; Kwok, TT; Tsang, WP | 1 |
| Bernhart, E; Hammer, A; Kratzer, I; Malle, E; Panzenboeck, U; Reicher, H; Sattler, W; Wernig, K; Windisch, M; Wronski, R; Zimmer, A | 1 |
| von Mehren, M | 1 |
| Burley, GA; Carell, T; Gierlich, J; Gutsmiedl, K; Ravoo, BJ; Reinhoudt, DN; Rozkiewicz, DI | 1 |
| Bui, B; Italiano, A | 1 |
| Beisner, J; Dong, M; Friedel, G; Kleideiter, E; Klotz, U; Lehr, CM; Mürdter, TE; Piotrowska, K; Schaefer, U; Taetz, S | 1 |
| da Silveira, MU; de Oliveira, MC; Dos Santos Giuberti, C; Dos Santos, GR; Fraga, M; Laux, M; Teixeira, HF; Zandoná, B | 1 |
| Kiselyov, AS; Semenov, VV; Semenova, M | 1 |
| Agrawal, S; Bett, AJ; Casimiro, DR; Dubey, SA; Jiang, W; Kandimalla, ER; Nowak, I; Precopio, M; Putta, MR; Struthers, M; Sun, Z; Tang, JX; Wang, H; Wisniewski, T; Yu, D | 1 |
| Jia, SM; Kong, DM; Li, P; Liu, XF; Shen, HX | 1 |
| Butchi, NB; Du, M; Peterson, KE; Woods, T | 1 |
| Cheng, Q; Geng, F; Wang, Y; Xu, H; Xu, M | 1 |
| Cabrera, BL; Carethers, JM; Iwaizumi, M; Tajima, A; Tseng-Rogenski, S | 1 |
| Geng, F; Qu, P; Wang, Y; Xu, H; Xu, M; Zhou, X | 1 |
| Ju, E; Li, Z; Liu, Z; Qu, X; Ren, J; Zhou, L | 1 |
| Bai, WD; Bai, XZ; Cai, WX; Hu, DH; Jia, YH; Li, C; Li, J; Li, Y; Liu, JQ; Shi, JH; Su, LL; Wu, X; Zhao, B; Zhu, HY | 1 |
| Hodges, MR; Ottosen, S; Parsley, TB; Patick, AK; Raney, AK; van der Veer, E; van Doorn, LJ; Yang, L; Zeh, K | 1 |
| Gulappa, T; Menon, B; Menon, KM | 1 |
| Guo, Z; Hao, Q; Jiang, W; Liu, Y; Rustam, B; Zhu, J | 1 |
| Kiernan, MC | 1 |
| Deng, Z; Fang, N; Ma, C; Tang, Z; Wang, K; Wu, K; Zhu, X | 1 |
| Hussar, DA | 1 |
| Marafini, I; Monteleone, G; Salvatori, S; Troncone, E | 1 |
| Chen, JJ | 1 |
3 review(s) available for thiazoles and oligonucleotides
| Article | Year |
|---|---|
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bevacizumab; Clinical Trials as Topic; Dasatinib; Drug Resistance, Neoplasm; Everolimus; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Niacinamide; Oligonucleotides; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sirolimus; Staurosporine; Sunitinib; Thiazoles | 2006 |
[Gastrointestinal stromal tumors: molecular aspects and therapeutic implications].
Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Proteins; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sorafenib; Staurosporine; Sunitinib; Thiazoles | 2008 |
TGF-β activity restoration and phosphodiesterase 4 inhibition as therapeutic options for inflammatory bowel diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Oligonucleotides; Phosphodiesterase 4 Inhibitors; Thalidomide; Thiazoles; Transforming Growth Factor beta | 2020 |
1 trial(s) available for thiazoles and oligonucleotides
| Article | Year |
|---|---|
In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122.
Topics: 5' Untranslated Regions; Antiviral Agents; Carbamates; Cyclohexanols; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Macrocyclic Compounds; MicroRNAs; Molecular Targeted Therapy; Mutation; Oligonucleotides; Oligopeptides; Pyrrolidines; Quinolines; Replicon; Thiazoles; Thiophenes; Valine | 2015 |
47 other study(ies) available for thiazoles and oligonucleotides
| Article | Year |
|---|---|
Incorporation of 3-methyl-2-benzothiazolone hydrazone into the anticodon loop of tRNA Phe from yeast.
Topics: Benzothiazoles; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Genetic Code; Hydrazones; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oligonucleotides; Pentosephosphates; Phenylalanine; Ribose; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Thiazoles; Transfer RNA Aminoacylation | 1972 |
Bis-intercalation of a homodimeric thiazole orange dye in DNA in symmetrical pyrimidine-pyrimidine-purine-purine oligonucleotides.
Topics: Base Sequence; Benzothiazoles; DNA; Fluorescent Dyes; Molecular Sequence Data; Oligonucleotides; Purines; Pyrimidines; Quinolines; Thiazoles | 1996 |
Evaluation of 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) as a new sulfurizing reagent in combination with labile exocyclic amino protecting groups for solid-phase oligonucleotide synthesis.
Topics: Molecular Probe Techniques; Oligonucleotides; Thiazoles | 1997 |
Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Gene Expression; Glomerular Mesangium; Nuclear Proteins; Oligonucleotides; Prostaglandin D2; Protein Binding; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
Steric control of DNA interstrand cross-link sites of trans platinum complexes: specificity can be dictated by planar nonleaving groups.
Topics: Antineoplastic Agents; Base Sequence; Cisplatin; Cross-Linking Reagents; Cytosine; DNA; DNA Adducts; DNA Footprinting; Guanine; Ligands; Nucleic Acid Conformation; Oligonucleotides; Quinolines; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2000 |
Interaction of cyanine dyes with nucleic acids. Part 19: new method for the covalent labeling of oligonucleotides with pyrylium cyanine dyes.
Topics: Amines; Chromatography, High Pressure Liquid; Fluorescent Dyes; Molecular Structure; Oligonucleotides; Staining and Labeling; Thiazoles | 2000 |
Solution structure of Co(III)-bleomycin-OOH bound to a phosphoglycolate lesion containing oligonucleotide: implications for bleomycin-induced double-strand DNA cleavage.
Topics: Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Bleomycin; DNA; DNA Damage; Glycolates; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Oligodeoxyribonucleotides; Oligonucleotides; Protons; Solutions; Thiazoles; Titrimetry | 2001 |
Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine.
Topics: Aspartic Acid Endopeptidases; Drug Resistance; HIV Protease; HIV Protease Inhibitors; Inhibitory Concentration 50; Mutagenesis; Oligonucleotides; Phenylbutyrates; Protease Inhibitors; Structure-Activity Relationship; Thiazoles | 2001 |
DNA alkylation by leinamycin can be triggered by cyanide and phosphines.
Topics: Alkylation; Antibiotics, Antineoplastic; Cyanides; DNA; DNA Damage; Electrophoresis, Polyacrylamide Gel; Lactams; Macrolides; Oligonucleotides; Phosphines; Plasmids; Thiazoles; Thiones | 2001 |
Oligonucleotide-conjugated thiazole orange probes as "light-up" probes for messenger ribonucleic acid molecules in living cells.
Topics: Absorptiometry, Photon; Animals; Base Pairing; Benzothiazoles; Chromatography, High Pressure Liquid; Coleoptera; DNA Probes; Fluorescein; Fluorescent Dyes; Humans; In Situ Hybridization, Fluorescence; Luciferases; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Nucleic Acid Hybridization; Oligonucleotides; Osteosarcoma; Quinolines; RNA, Messenger; RNA, Transfer; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Stereoisomerism; Thiazoles; Time Factors; Tumor Cells, Cultured | 2001 |
Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules.
Topics: 12E7 Antigen; Adaptor Proteins, Signal Transducing; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Apoptosis; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Line; Cell Nucleus; Co-Repressor Proteins; Cross-Linking Reagents; DNA, Complementary; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Hematopoietic Stem Cells; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Kinetics; Leukocyte Common Antigens; Leukosialin; Molecular Chaperones; NF-kappa B; Nuclear Proteins; Oligonucleotides; Plasmids; Protein Binding; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Two-Hybrid System Techniques | 2002 |
Synthesis of oligonucleotides containing thiazole and thiazole N-oxide nucleobases.
Topics: Crystallography, X-Ray; Models, Molecular; Nucleosides; Oligonucleotides; Thiazoles | 2002 |
Fluorescent properties of oligonucleotide-conjugated thiazole orange probes.
Topics: Benzothiazoles; Fluorescent Dyes; Oligonucleotides; Quinolines; Thiazoles | 2002 |
PPAR gamma ligands, troglitazone and pioglitazone, up-regulate expression of HMG-CoA synthase and HMG-CoA reductase gene in THP-1 macrophages.
Topics: Cell Differentiation; Cell Line; Cholesterol; Chromans; Coenzyme A Ligases; DNA, Antisense; Dose-Response Relationship, Drug; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Macrophages; Oligonucleotides; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Response Elements; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2002 |
Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Cycle Proteins; Cell Line; Cell Nucleus; Cloning, Molecular; Coloring Agents; DNA, Complementary; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Gene Expression Regulation; Humans; Models, Biological; Neoplasms, Glandular and Epithelial; Oligonucleotides; Oligonucleotides, Antisense; Open Reading Frames; Plasmids; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins c-myc; Retinoids; Retroviridae; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2003 |
Triphenyl tin benzimidazolethiol, a novel antitumor agent, induces mitochondrial-mediated apoptosis in human cervical cancer cells via suppression of HPV-18 encoded E6.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Benzimidazoles; Caspases; Cell Line, Tumor; Cell Separation; DNA; Down-Regulation; Female; Flow Cytometry; Fluorescent Dyes; G1 Phase; HeLa Cells; Humans; Membrane Proteins; Mitochondria; Models, Chemical; Oligonucleotides; Organotin Compounds; Poly(ADP-ribose) Polymerases; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation; Uterine Cervical Neoplasms | 2003 |
Sequence specificity of DNA alkylation by the antitumor natural product leinamycin.
Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Cattle; DNA; DNA, Single-Stranded; Fishes; Guanine; Lactams; Macrolides; Male; Molecular Sequence Data; Mustard Gas; Oligonucleotides; Perchlorates; Phosphoric Monoester Hydrolases; Plasmids; Sodium Compounds; Spermatozoa; Substrate Specificity; Sulfuric Acid Esters; Thiazoles; Thiones | 2003 |
CpG immunostimulatory oligodeoxynucleotide 1826 enhances antitumor effect of interleukin 12 gene-modified tumor vaccine in a melanoma model in mice.
Topics: Animals; Antineoplastic Agents; Cancer Vaccines; Cell Line, Tumor; CpG Islands; Cytokines; Disease Progression; DNA; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Dyes; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Interleukin-12; Lymphatic Metastasis; Macrophages; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Oligonucleotides; Spleen; Tetrazolium Salts; Th1 Cells; Thiazoles; Time Factors | 2004 |
The yeast dynamin-related GTPase Vps1p functions in the organization of the actin cytoskeleton via interaction with Sla1p.
Topics: Actins; Amino Acid Sequence; Biological Transport; Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Cathepsin A; Cell Death; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Dynamins; Endocytosis; Genotype; GTP Phosphohydrolases; GTP-Binding Proteins; Immunoprecipitation; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides; Plasmids; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; src Homology Domains; Temperature; Thiazoles; Thiazolidines; Time Factors; Vesicular Transport Proteins | 2004 |
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity.
Topics: Agar; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; DNA; Dose-Response Relationship, Drug; Doxorubicin; Epithelial Cells; Flow Cytometry; Fluorouracil; Genes, Dominant; Humans; Immunohistochemistry; Mice; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides; Phenotype; rhoA GTP-Binding Protein; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Wound Healing | 2004 |
Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Female; Humans; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tetrazolium Salts; Thiazoles; Thionucleotides; Time Factors; Up-Regulation | 2004 |
Chemoselective oxime and thiazolidine bond formation: a versatile and efficient route to the preparation of 3'-peptide-oligonucleotide conjugates.
Topics: Oligonucleotides; Oximes; Peptides; Spectrophotometry, Ultraviolet; Thiazoles | 2004 |
Synthesis and fluorescence studies of thiazole orange tethered onto oligonucleotide: development of a self-contained DNA biosensor on a fiber optic surface.
Topics: Base Sequence; Benzothiazoles; Biosensing Techniques; DNA; Fiber Optic Technology; Fluorescent Dyes; Molecular Structure; Oligonucleotides; Optical Fibers; Quinolines; Spectrometry, Fluorescence; Thiazoles | 2005 |
Water-soluble hybrid nanoclusters with extra bright and photostable emissions: a new tool for biological imaging.
Topics: Amyloid; Animals; Benzothiazoles; Biophysics; Culture Techniques; Fluorescent Dyes; Insulin; Light; Mice; Microscopy, Confocal; Microscopy, Electron; Microscopy, Fluorescence; Nanostructures; Oligonucleotides; Prions; Scattering, Radiation; Silver; Sodium; Spectrometry, Fluorescence; Thiazoles; Time Factors; Water | 2005 |
The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor.
Topics: Apoptosis; Benzothiazoles; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP1A1; DNA; Electrophoretic Mobility Shift Assay; Humans; Ligands; Oligonucleotides; Plasmids; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Toluene; Transfection; Tumor Suppressor Protein p53 | 2005 |
Chrysoeriol potently inhibits the induction of nitric oxide synthase by blocking AP-1 activation.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Digitalis; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavones; Flavonoids; Immunoblotting; Lipopolysaccharides; Macrophages; Male; Mice; Models, Chemical; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligonucleotides; Plant Leaves; Promoter Regions, Genetic; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor AP-1 | 2005 |
Sequence-specific fluorescence detection of DNA by polyamide-thiazole orange conjugates.
Topics: Base Sequence; Benzothiazoles; DNA; Fluorescent Dyes; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Denaturation; Nylons; Oligonucleotides; Quinolines; Thiazoles | 2005 |
Epidermal growth factor induction of resistance to topoisomerase II toxins in human squamous carcinoma A431 cells.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; Down-Regulation; Drug Resistance, Neoplasm; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Oligonucleotides; Phosphorylation; Tetrazolium Salts; Thiazoles; Tyrosine | 2006 |
Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier.
Topics: Animals; Apolipoprotein A-I; Astrocytes; Blood-Brain Barrier; Blotting, Western; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Coculture Techniques; Endothelial Cells; Fluorescent Antibody Technique; Humans; Lipoproteins, HDL; Nanoparticles; Oligonucleotides; Particle Size; Protamines; Spectrometry, Mass, Electrospray Ionization; Swine; Tetrazolium Salts; Thiazoles | 2007 |
Transfer printing of DNA by "click" chemistry.
Topics: Acetylene; Combinatorial Chemistry Techniques; Dendrimers; DNA; Glass; Membranes, Artificial; Microscopy, Atomic Force; Microscopy, Fluorescence; Molecular Conformation; Oligonucleotides; Particle Size; Structure-Activity Relationship; Surface Properties; Thiazoles | 2007 |
Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA.
Topics: Antineoplastic Agents; Capillary Electrochromatography; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cholesterol; Drug Delivery Systems; Enzyme Inhibitors; Excipients; Fatty Acids, Monounsaturated; Humans; Indicators and Reagents; Liposomes; Lung Neoplasms; Microscopy, Confocal; Oligonucleotides; Oligonucleotides, Antisense; Quaternary Ammonium Compounds; RNA, Antisense; Telomerase; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Evaluation of the toxicity of oligonucleotide/cationic nanoemulsion complexes on Hep G2 cells through MTT assay.
Topics: Cations; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Coloring Agents; Drug Screening Assays, Antitumor; Emulsions; Humans; Nanoparticles; Oligonucleotides; Tetrazolium Salts; Thiazoles; Viscosity | 2008 |
3,4-Disubstituted isothiazoles: novel potent inhibitors of VEGF receptors 1 and 2.
Topics: Adenosine Triphosphate; Caco-2 Cells; Combinatorial Chemistry Techniques; Drug Design; Humans; Indoles; Molecular Structure; Niacinamide; Oligonucleotides; Phthalazines; Pyridines; Structure-Activity Relationship; Thiazoles; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
Synthesis and immunological activities of novel agonists of toll-like receptor 9.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Proliferation; Dendritic Cells; Female; Humans; Interferon-alpha; Lymphocyte Activation; Macaca mulatta; Mice; Mice, Inbred C57BL; Oligonucleotides; Pyrimidinones; Thiazoles; Toll-Like Receptor 9 | 2010 |
G-quadruplex DNAzyme-based Hg2+ and cysteine sensors utilizing Hg2+-mediated oligonucleotide switching.
Topics: Benzothiazoles; Biosensing Techniques; Colorimetry; Cysteine; DNA, Catalytic; Environmental Pollutants; G-Quadruplexes; Hemin; Limit of Detection; Mercury; Oligonucleotides; Sulfonic Acids; Thiazoles | 2011 |
Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8.
Topics: Animals; Cell Shape; Cerebral Cortex; Cytokines; Down-Regulation; Endocytosis; Endosomes; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neuroglia; Oligonucleotides; Poly T; Quinolines; RNA, Messenger; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8; Up-Regulation | 2011 |
Oligonucleotide-based label-free Hg2+ assay with a monomer-excimer fluorescence switch.
Topics: Benzothiazoles; Hydrogen-Ion Concentration; Mercury; Oligonucleotides; Spectrometry, Fluorescence; Thiazoles | 2011 |
Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Baculoviridae; Cell Line, Tumor; Colonic Neoplasms; Cross-Linking Reagents; DNA Mismatch Repair; DNA-Binding Proteins; Fluorouracil; Humans; Microsatellite Repeats; Oligonucleotides; Recombinant Proteins; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Treatment Outcome | 2011 |
A label-free oligonucleotide based thioflavin-T fluorescent switch for Ag+ detection with low background emission.
Topics: Benzothiazoles; Fluorescence; Fluorescent Dyes; Oligonucleotides; Silver; Spectrometry, Fluorescence; Thiazoles | 2012 |
Aptamer-directed synthesis of multifunctional lanthanide-doped porous nanoprobes for targeted imaging and drug delivery.
Topics: Cell Line; Cell Line, Tumor; Contrast Media; DNA; Drug Delivery Systems; Humans; Lanthanoid Series Elements; MCF-7 Cells; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Neoplasms; Oligonucleotides; Porosity; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2013 |
MicroRNA-21 regulates hTERT via PTEN in hypertrophic scar fibroblasts.
Topics: Blotting, Western; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Gene Expression Regulation; Humans; Immunohistochemistry; Luciferases; MicroRNAs; Oligonucleotides; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Signal Transduction; Telomerase; Tetrazolium Salts; Thiazoles | 2014 |
miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries.
Topics: Animals; Antagomirs; Chorionic Gonadotropin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation; MAP Kinase Signaling System; MicroRNAs; Oligonucleotides; Ovary; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Rats, Sprague-Dawley; Receptors, LH; Ribonucleoproteins; RNA-Binding Proteins; Sterol Regulatory Element Binding Proteins; Thiazoles | 2015 |
Integrating DNA structure switch with branched hairpins for the detection of uracil-DNA glycosylase activity and inhibitor screening.
Topics: Base Pairing; Benzothiazoles; DNA; Enzyme Inhibitors; Fluorescent Dyes; G-Quadruplexes; HeLa Cells; High-Throughput Screening Assays; Humans; Inverted Repeat Sequences; Limit of Detection; MCF-7 Cells; Oligonucleotides; Spectrometry, Fluorescence; Thiazoles; Uracil-DNA Glycosidase | 2018 |
Motor neuron disease in 2017: Progress towards therapy in motor neuron disease.
Topics: Amyotrophic Lateral Sclerosis; Benzamides; Edaravone; Humans; Muscular Atrophy, Spinal; Neuroprotective Agents; Oligonucleotides; Oligoribonucleotides, Antisense; Piperidines; Pyridines; Thiazoles; Thionucleotides | 2018 |
Label-free and nicking enzyme-assisted fluorescence signal amplification for RNase H determination based on a G-quadruplexe/thioflavin T complex.
Topics: Benzothiazoles; Biological Assay; Deoxyribonucleases, Type II Site-Specific; DNA, Single-Stranded; Fluorescence; Fluorescent Dyes; G-Quadruplexes; Gentamicins; Humans; Inverted Repeat Sequences; Limit of Detection; Oligonucleotides; Protein Synthesis Inhibitors; Ribonuclease H; RNA; Spectrometry, Fluorescence; Thiazoles | 2018 |
New Drugs 2019, part 4.
Topics: Aminopyridines; Cinnamates; Drug Approval; Factor Xa; Humans; Macrolides; Morpholines; Oligonucleotides; Oxazines; Pyridines; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Sisomicin; Tetracyclines; Thiazoles; Thiophenes; United States; United States Food and Drug Administration | 2019 |
Overview of current and emerging therapies for amytrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Antibodies, Monoclonal, Humanized; Benzamides; Edaravone; Humans; Mesenchymal Stem Cells; Oligonucleotides; Piperidines; Pyridines; Riluzole; Thiazoles | 2020 |