Page last updated: 2024-08-21

thiazoles and olaparib

thiazoles has been researched along with olaparib in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Kang, T; Lin, Y; Zhou, BP1
Ledermann, JA1
Aghajanian, C; Barry, WT; Birrer, M; Buss, MK; Cadoo, KA; Cantley, LC; Coleman, RL; Curtis, J; D'Andrea, AD; Eismann, J; Farooq, S; Kaufmann, SH; Kirschmeier, P; Kochupurakkal, B; Konstantinopoulos, PA; Liu, J; Luo, W; Matulonis, UA; Mayer, EL; Mills, GB; O'Cearbhaill, RE; Palakurthi, S; Shapiro, GI; Swisher, EM; Westin, SN; Whalen, C; Winer, E; Wulf, GM1
Adalsteinsson, V; Batalini, F; Cantley, LC; D'Andrea, A; Eismann, J; Konstantinopoulos, PA; Matulonis, UA; Mayer, EL; Polak, M; Shapiro, GI; Swisher, EM; Tayob, N; Winer, EP; Wulf, GM; Xiong, N1

Trials

2 trial(s) available for thiazoles and olaparib

ArticleYear
Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial.
    The Lancet. Oncology, 2019, Volume: 20, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovarian Epithelial; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Genome, Human; Humans; Maximum Tolerated Dose; Middle Aged; Mutation; Ovarian Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Thiazoles; Treatment Outcome

2019
Phase 1b Clinical Trial with Alpelisib plus Olaparib for Patients with Advanced Triple-Negative Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 04-14, Volume: 28, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell-Free Nucleic Acids; Female; Humans; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Thiazoles; Triple Negative Breast Neoplasms

2022

Other Studies

2 other study(ies) available for thiazoles and olaparib

ArticleYear
Doxorubicin enhances Snail/LSD1-mediated PTEN suppression in a PARP1-dependent manner.
    Cell cycle (Georgetown, Tex.), 2014, Volume: 13, Issue:11

    Topics: Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Methylation; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; HEK293 Cells; Histone Demethylases; Humans; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Snail Family Transcription Factors; Tetrazolium Salts; Thiazoles; Transcription Factors

2014
Extending the scope of PARP inhibitors in ovarian cancer.
    The Lancet. Oncology, 2019, Volume: 20, Issue:4

    Topics: Carcinoma, Ovarian Epithelial; Female; Humans; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Thiazoles

2019