Page last updated: 2024-08-21

thiazoles and nosiheptide

thiazoles has been researched along with nosiheptide in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19909 (13.85)18.7374
1990's3 (4.62)18.2507
2000's11 (16.92)29.6817
2010's37 (56.92)24.3611
2020's5 (7.69)2.80

Authors

AuthorsStudies
Gaillard, C; Moreau, MO; Pascal, C1
Ducruix, A; Lunel, J; Pascard, C; Prangé, T1
Dosch, DC; Floss, HG; Li, Y; Strohl, WR; Woodman, RH1
Alekseeva, LE; Kononovich, TA; Sokolov, LB1
Dosch, DC; Floss, HG; Li, Y; Strohl, WR1
Dary, A; Decaris, B; Simonet, B; Simonet, JM1
Beale, JM; Chen, LC; Floss, HG; Houck, DR; Keller, PJ; Mocek, U1
Dosch, DC; Floss, HG; Strohl, WR1
Cromwell, GL; O'Kelly, R; Speer, VC; Stahly, TS1
Benazet, F; Cartier, JR1
Cundliffe, E; Thompson, J1
Benazet, F; Cartier, M; Dubost, M; Florent, J; Godard, C; Jung, G; Lunel, J; Mancy, D; Ninet, L; Pascal, C; Renaut, J; Tarridec, P; Theilleux, J; Tissier, R1
Aboul-ela, F; Klinck, R; Lentzen, G; Matassova, N; Murchie, AI1
Bentley, DJ; Fairhurst, J; Gallagher, PT; Manteuffel, AK; Moody, CJ; Pinder, JL1
Cai, QS; Feng, MQ; Huang, H; Zhou, P1
Arndt, HD; Lu, JY1
Kimber, MC; Moody, CJ1
Bai, L; Fen, M; Shi, X; Zhang, X; Zhou, P1
Connell, SR; Fucini, P; Harms, JM; Schluenzen, F; Spahn, CM; Stachelhaus, T; Wilson, DN; Zaborowska, Z1
Cai, Q; Feng, M; Guo, X; Huang, H; Shi, X; Zhou, P1
Ding, Y; Duan, L; Liao, R; Liu, W; Pan, H; Shen, B; Tang, G; Wendt-Pienkowski, E; Yu, Y; Zhang, Q1
Arndt, HD; Lu, JY; Mikyna, M; Riedrich, M1
Chen, DY; Cooperman, BS; Leung, GY; Mikolajka, A; Nicolaou, KC; Qin, H; Schwinghammer, K; Starosta, AL; Wilson, DN1
Dong, Z; Gong, R; Li, X; Li, Z; Wang, P; Xu, Y; Yang, H; Yang, Y1
Chen, D; Gong, R; Jia, X; Li, Z; Murchie, AI; Shen, Y; Wang, P; Wang, Z; Xu, Y; Yang, H; Yang, Y; Zhao, L; Zhou, P1
Ding, Y; Duan, L; Guo, H; Lei, C; Liao, R; Liu, W; Shen, B; Yu, Y; Zhang, Q1
Chen, D; Duan, L; Li, Y; Liu, W; Shen, B; Yu, Y; Zhang, Q1
Arcinas, AJ; Booker, SJ1
Chen, BJ; Chen, CY; Chou, IP; Hsieh, YH; Li, YH; Wang, HT1
Kelly, WL; Zhang, F1
Fenical, W; Haste, NM; Hensler, ME; Jensen, PR; Loesgen, S; Nam, SJ; Nizet, V; Sakoulas, G; Sun, P; Thienphrapa, W; Tran, DN1
Chen, Y; Liu, N; Liu, W; Ma, M; Wang, S; Xue, Y2
Liu, W; Wang, S; Zhou, S1
Li, Y; Liang, X; Wang, C; Wang, Q; Zhang, D; Zhang, F1
Chen, Y; Kong, L; Liu, W; Ma, M; Wang, S; Xue, Y; Zhang, H1
Liu, X; Shi, X; Zhang, P; Zhou, P; Zhou, W1
Chen, D; Jiang, H; Murchie, AI; Yin, S1
Ding, W; Ji, X; Li, Y; Zhang, Q1
Cao, C; Ding, J; Guo, H; Han, L; Lan, W; Liu, S; Liu, W; Rong, N; Wang, C; Wang, R; Yao, P; Yu, Y; Zhang, T; Zhang, Y1
Cao, C; Ding, J; Lan, W; Liu, S; Liu, W; Wang, C; Wang, Y; Yao, P; Yu, Y; Zhang, Y1
Aita, N; Asao, M; Chihara, T; Shimamura, C; Yamata, T1
Chen, YJ; Jiang, L; Liu, WY; Ma, M; Wang, SZ; Wu, XR; Xue, YJ1
Liu, Q; Mo, Q; Song, Y; Tang, X; Zan, X; Zhang, H; Zhao, L1
Chen, Y; Jin, L; Jin, Y; Wang, S; Wu, X; Xue, Y1
Chen, F; Deng, Z; Ding, W; Ji, X; Li, Y; Mo, T; Qianzhu, H; Tu, T; Yu, Y; Zhang, Q; Zhao, J1
Galster, J; Picou, EM; Ricketts, TA1
Badding, ED; Boal, AK; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW1
Chen, H; Gu, Z; Liu, B; Ni, H; Wang, D; Wang, Z; Zhao, X1
Deng, Z; Ding, W; Ji, W; Liu, WQ; Ma, X; Mo, T; Tang, B; Wu, R; Wu, Y; Xu, P; Yu, Y; Zhang, Q; Zhang, W; Zhao, J1
Chen, Y; Jin, L; Ma, M; Tong, R; Wu, X; Zhang, H1
Badding, ED; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW; Wang, B2
Guo, H; Li, J; Li, Y; Lin, Z; Liu, W; Niu, G; Qiu, Y; Tan, H1
Du, Y; Guo, Y; Liao, R; Liu, W; Peng, C; Qiu, Y; Zhang, F; Zhou, S1
Arndt, HD; Roessler, C1
Begley, TP; Bhandari, DM; Fedoseyenko, D1
He, L; Li, X; Song, X; Xie, J; Zhang, M; Zhang, Y1
Booker, SJ; LaMattina, JW; Marshall, SL; Wang, B1
Jin, WB; Tang, GL; Wu, S; Xu, YF; Yuan, H1
He, L; Li, X; Martín-Esteban, A; Qiu, J; Song, X; Su, Y; Xie, J1
de Vries, RH; Kuipers, OP; Roelfes, G; Viel, JH1
Chen, H; Fan, Y; Mu, N; Ruan, Z; Wang, S; Wang, W; Zhu, K1
Chen, Y; Tan, Y; Wang, M1
Chen, D; Guo, H; Liu, W; Mu, N; Wang, S; Wang, W; Yin, Y; Zhang, E1

Reviews

4 review(s) available for thiazoles and nosiheptide

ArticleYear
Transcriptional organization and regulation of the nosiheptide resistance gene in Streptomyces actuosus.
    Journal of industrial microbiology, 1991, Volume: 8, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Molecular Sequence Data; Molecular Structure; Multigene Family; Open Reading Frames; Promoter Regions, Genetic; Restriction Mapping; Streptomyces; Thiazoles; Transcription, Genetic

1991
Opportunities and challenges from current investigations into the biosynthetic logic of nosiheptide-represented thiopeptide antibiotics.
    Current opinion in chemical biology, 2013, Volume: 17, Issue:4

    Topics: Anti-Bacterial Agents; Cycloaddition Reaction; Hydrogenation; Thiazoles

2013
Recent advances in HemN-like radical S-adenosyl-l-methionine enzyme-catalyzed reactions.
    Natural product reports, 2020, 01-01, Volume: 37, Issue:1

    Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Duocarmycins; Enzymes; Escherichia coli Proteins; Heme; Hydrogen; Methylation; Peptides, Cyclic; Polyketides; Protein Methyltransferases; S-Adenosylmethionine; Thiazoles

2020
Mutasynthesis Generates Antibacterial Benzothiophenic-Containing Nosiheptide Analogues.
    Journal of natural products, 2022, 10-28, Volume: 85, Issue:10

    Topics: Anti-Bacterial Agents; Thiazoles; Thiophenes

2022

Trials

1 trial(s) available for thiazoles and nosiheptide

ArticleYear
Albusin B modulates lipid metabolism and increases antioxidant defense in broiler chickens by a proteomic approach.
    Journal of the science of food and agriculture, 2013, Volume: 93, Issue:2

    Topics: Animals; Antioxidants; ATP-Binding Cassette Transporters; Bacteriocins; Chickens; Diet; Dietary Supplements; Down-Regulation; Enzyme Induction; Fatty Acid-Binding Proteins; Female; Gene Expression Profiling; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Jejunum; Lipid Metabolism; Liver; Male; Recombinant Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles; Weight Gain

2013

Other Studies

60 other study(ies) available for thiazoles and nosiheptide

ArticleYear
Identification of nosiheptide in feeds and detection of residues in animal tissues.
    Journal - Association of Official Analytical Chemists, 1979, Volume: 62, Issue:5

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Biological Assay; Chickens; Colorimetry; Fermentation; Swine; Thiazoles; Tissue Distribution

1979
Highly modified cysteine-containing antibiotics. Chemical structure and configuration of nosiheptide.
    Journal of the American Chemical Society, 1977, Sep-14, Volume: 99, Issue:19

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cysteine; Methods; Molecular Conformation; Thiazoles

1977
[Structure of the chromophore fragment of copsomycin].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1990, Volume: 35, Issue:7

    Topics: Anti-Bacterial Agents; Hydrolysis; Methyl Ethers; Thiazoles

1990
Nucleotide sequence and transcriptional analysis of the nosiheptide-resistance gene from Streptomyces actuosus.
    Gene, 1990, Jul-02, Volume: 91, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Codon; Drug Resistance, Microbial; Genes, Bacterial; Molecular Sequence Data; Promoter Regions, Genetic; R Factors; Restriction Mapping; Sequence Homology, Nucleic Acid; Streptomyces; Thiazoles; Transcription, Genetic

1990
[Cloning of a nosiheptide-resistant gene from Streptomyces actuosus].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1989, Volume: 308, Issue:2

    Topics: Anti-Bacterial Agents; DNA Probes; Drug Resistance, Microbial; Genes, Bacterial; Genetic Vectors; Plasmids; Streptomyces; Thiazoles

1989
1H and 13C NMR assignments of the thiopeptide antibiotic nosiheptide.
    The Journal of antibiotics, 1989, Volume: 42, Issue:11

    Topics: Anti-Bacterial Agents; Carbon Isotopes; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Structure; Thiazoles

1989
Molecular cloning of the nosiheptide resistance gene from Streptomyces actuosus ATCC 25421.
    Biochemical and biophysical research communications, 1988, Oct-14, Volume: 156, Issue:1

    Topics: Anti-Bacterial Agents; Blotting, Southern; Cloning, Molecular; DNA Restriction Enzymes; Drug Resistance, Microbial; Genes, Bacterial; Nucleotide Mapping; Plasmids; Streptomyces; Thiazoles

1988
Efficacy of nosiheptide as a growth promotant for growing-finishing swine--a cooperative study.
    Journal of animal science, 1984, Volume: 59, Issue:5

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Body Weight; Female; Food Additives; Male; Swine; Thiazoles

1984
Effect of nosiheptide as a feed additive in chicks on the quantity, duration, prevalence of excretion, and resistance to antibacterial agents of Salmonella typhimurium; on the proportion of Escherichia coli and other coliforms resistant to antibacterial a
    Poultry science, 1980, Volume: 59, Issue:7

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Chickens; Drug Resistance, Microbial; Escherichia coli; Feces; Poultry Diseases; Salmonella Infections; Salmonella Infections, Animal; Salmonella typhimurium; Thiazoles

1980
The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism.
    Journal of general microbiology, 1981, Volume: 126, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Escherichia coli; Methylation; Pentoses; Peptide Elongation Factors; Ribosomes; Streptomyces; Thiazoles; Thiostrepton

1981
Nosiheptide, a sulfur-containing peptide antibiotic isolated from Streptomyces actuosus 40037.
    Experientia, 1980, Apr-15, Volume: 36, Issue:4

    Topics: Animal Feed; Animals; Anti-Bacterial Agents; Bacteria; Chickens; Drug Evaluation, Preclinical; Food Additives; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Streptomyces; Swine; Thiazoles

1980
Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
    Chemistry & biology, 2003, Volume: 10, Issue:8

    Topics: Anti-Bacterial Agents; Bacteriocins; Base Sequence; Binding Sites; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Thiazoles; Thiostrepton

2003
Synthesis of the 2,3,4-trisubstituted indole fragments of nosiheptide and glycothiohexide.
    Organic & biomolecular chemistry, 2004, Mar-07, Volume: 2, Issue:5

    Topics: Doxorubicin; Indoles; Lactones; Molecular Structure; Peptides; Thiazoles

2004
[Preparation of nosiheptide liposomes and its inhibitory effect on hepatitics B virus in vitro].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:5

    Topics: Antiviral Agents; Cell Line, Tumor; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatoblastoma; Humans; Liposomes; Liver Neoplasms; Particle Size; Thiazoles

2005
Hetero Diels-Alder synthesis of 3-hydroxypyridines: access to the nosiheptide core.
    The Journal of organic chemistry, 2007, May-25, Volume: 72, Issue:11

    Topics: Catalysis; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Pyridines; Stereoisomerism; Thiazoles

2007
Construction of macrocyclic thiodepsipeptides: synthesis of a nosiheptide 'southern hemisphere' model system.
    Chemical communications (Cambridge, England), 2008, Feb-07, Issue:5

    Topics: Cyclization; Depsipeptides; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Stereoisomerism; Sulfhydryl Compounds; Thiazoles

2008
Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide.
    Applied microbiology and biotechnology, 2008, Volume: 78, Issue:6

    Topics: Cysteine; Gene Expression; Genetic Engineering; Industrial Microbiology; Methionine Adenosyltransferase; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Streptomyces; Thiazoles

2008
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
    Molecular cell, 2008, Apr-11, Volume: 30, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Binding Sites; Crystallography, X-Ray; Deinococcus; Gene Expression Regulation; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptides; Protein Biosynthesis; Protein Structure, Tertiary; Ribosomal Proteins; Ribosomes; Thiazoles; Thiostrepton

2008
Recombinant high-density lipoprotein complex as a targeting system of nosiheptide to liver cells.
    Journal of drug targeting, 2008, Volume: 16, Issue:6

    Topics: Animals; Antiviral Agents; Apolipoprotein A-I; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Drug Stability; Feasibility Studies; Hepatitis B virus; Hepatocytes; Lipoproteins, HDL; Liposomes; Male; Microscopy, Electron, Transmission; Particle Size; Rats; Rats, Wistar; Recombinant Proteins; Thiazoles; Tissue Distribution

2008
Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.
    ACS chemical biology, 2009, Oct-16, Volume: 4, Issue:10

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Molecular Structure; Multigene Family; Peptide Biosynthesis; Streptomyces; Thiazoles

2009
Aza-Wittig-supported synthesis of the A ring of nosiheptide.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:43

    Topics: Anti-Bacterial Agents; Aza Compounds; Stereoisomerism; Thiazoles

2009
Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays.
    Chemistry & biology, 2009, Oct-30, Volume: 16, Issue:10

    Topics: Anti-Bacterial Agents; Binding Sites; GTP Phosphohydrolases; Peptide Elongation Factor Tu; Peptides, Cyclic; Prodrugs; Protein Biosynthesis; Ribosomes; Thiazoles; Thiostrepton

2009
Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2010, May-01, Volume: 66, Issue:Pt 5

    Topics: Crystallization; Crystallography, X-Ray; Drug Resistance, Bacterial; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiazoles

2010
Crystal structure of the nosiheptide-resistance methyltransferase of Streptomyces actuosus.
    Biochemistry, 2010, Aug-03, Volume: 49, Issue:30

    Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Drug Resistance, Bacterial; Methylation; Methyltransferases; Protein Multimerization; RNA; Streptomyces; Substrate Specificity; Thiazoles

2010
NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
    Journal of the American Chemical Society, 2010, Nov-24, Volume: 132, Issue:46

    Topics: Amino Acid Sequence; Catalysis; Dealkylation; Molecular Sequence Data; Molecular Structure; Protein Precursors; Serine; Streptomyces; Thiazoles

2010
Radical-mediated enzymatic carbon chain fragmentation-recombination.
    Nature chemical biology, 2011, Volume: 7, Issue:3

    Topics: Binding Sites; Carbon; Catalysis; Chromatography, High Pressure Liquid; Free Radicals; Indoles; Peptides; S-Adenosylmethionine; Substrate Specificity; Thiazoles; Time Factors; Tryptophan

2011
Enzymology: Radical break-up, blissful make-up.
    Nature chemical biology, 2011, Volume: 7, Issue:3

    Topics: Anti-Bacterial Agents; Catalysis; Enzyme Activation; Enzymes and Coenzymes; Free Radicals; Models, Chemical; S-Adenosylmethionine; Thiazoles; Tryptophan

2011
In vivo production of thiopeptide variants.
    Methods in enzymology, 2012, Volume: 516

    Topics: Anti-Bacterial Agents; Genes, Bacterial; Genetic Engineering; Multigene Family; Peptide Biosynthesis; Peptides; Plasmids; Protein Precursors; Ribosomes; Streptomyces; Structure-Activity Relationship; Thiazoles; Thiostrepton

2012
Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus.
    The Journal of antibiotics, 2012, Volume: 65, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Streptomyces; Thiazoles; Time Factors; Vancomycin

2012
The C-terminal extended serine residue is absolutely required in nosiheptide maturation.
    Chembiochem : a European journal of chemical biology, 2013, Mar-18, Volume: 14, Issue:5

    Topics: Amides; Amino Acid Sequence; Amino Acids; Serine; Thiazoles

2013
Multiple oxidative routes towards the maturation of nosiheptide.
    Chembiochem : a European journal of chemical biology, 2013, Sep-02, Volume: 14, Issue:13

    Topics: Cytochrome P-450 Enzyme System; Molecular Structure; Oxidation-Reduction; Thiazoles

2013
Genome shuffling and ribosome engineering of Streptomyces actuosus for high-yield nosiheptide production.
    Applied biochemistry and biotechnology, 2014, Volume: 173, Issue:6

    Topics: Animal Feed; Anti-Bacterial Agents; DNA Shuffling; Fermentation; Food Additives; Genome, Bacterial; Industrial Microbiology; Mutagenesis; Ribosomes; Streptomyces; Thiazoles

2014
Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.
    Chemical communications (Cambridge, England), 2014, Sep-18, Volume: 50, Issue:72

    Topics: Bacterial Proteins; Base Sequence; Binding Sites; Biocatalysis; Escherichia coli; Genetic Vectors; Molecular Sequence Data; Multigene Family; Promoter Regions, Genetic; Protein Binding; Ribosomes; Streptomyces; Thiazoles

2014
Effect analysis of mineral salt concentrations on nosiheptide production by Streptomyces actuosus Z-10 using response surface methodology.
    Molecules (Basel, Switzerland), 2014, Sep-26, Volume: 19, Issue:10

    Topics: Culture Media; Fermentation; Minerals; Salts; Streptomyces; Thiazoles

2014
Substrate recognition and modification by the nosiheptide resistance methyltransferase.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Anti-Bacterial Agents; Binding Sites; Drug Resistance, Bacterial; Enzyme Activation; Methylation; Methyltransferases; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Multimerization; RNA; Substrate Specificity; Thiazoles

2015
Substrate-Tuned Catalysis of the Radical S-Adenosyl-L-Methionine Enzyme NosL Involved in Nosiheptide Biosynthesis.
    Angewandte Chemie (International ed. in English), 2015, Jul-27, Volume: 54, Issue:31

    Topics: Catalysis; Methionine; Molecular Structure; S-Adenosylmethionine; Thiazoles

2015
Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis.
    Scientific reports, 2015, Aug-05, Volume: 5

    Topics: Amide Synthases; Crystallography, X-Ray; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Thiazoles

2015
Crystallographic analysis of NosA, which catalyzes terminal amide formation in the biosynthesis of nosiheptide.
    Acta crystallographica. Section F, Structural biology communications, 2015, Volume: 71, Issue:Pt 8

    Topics: Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Gene Expression; Molecular Sequence Data; Peptides; Recombinant Fusion Proteins; Selenomethionine; Sequence Alignment; Streptomyces; Thiazoles

2015
[Validation Study on a Method of Determination of Nosiheptide in Formula Feeds by HPLC-FL].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2015, Volume: 56, Issue:4

    Topics: Animal Feed; Chromatography, High Pressure Liquid; Food Analysis; Laboratories; Observer Variation; Reproducibility of Results; Thiazoles

2015
The importance of start codon of nosM in nosiheptide production.
    Chinese journal of natural medicines, 2015, Volume: 13, Issue:11

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Codon, Initiator; Escherichia coli; Genes, Bacterial; Mutation; Streptomyces; Thiazoles

2015
Enhancing nosiheptide production in Streptomyces actuosus by heterologous expression of haemoprotein from Sinorhizobium meliloti.
    Letters in applied microbiology, 2016, Volume: 62, Issue:6

    Topics: Bacterial Proteins; Fermentation; Hemeproteins; Oxygen; Sinorhizobium meliloti; Streptomyces; Thiazoles; Vitreoscilla

2016
Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis.
    Applied and environmental microbiology, 2017, 02-15, Volume: 83, Issue:4

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Genes, Bacterial; Gram-Positive Bacteria; Protein Biosynthesis; Protein Sorting Signals; Streptomyces; Thiazoles

2017
The Catalytic Mechanism of the Class C Radical S-Adenosylmethionine Methyltransferase NosN.
    Angewandte Chemie (International ed. in English), 2017, 03-27, Volume: 56, Issue:14

    Topics: Anti-Bacterial Agents; Catalysis; Free Radicals; Methylation; Methyltransferases; Molecular Structure; S-Adenosylmethionine; Thiazoles

2017
Directional Microphone Hearing Aids in School Environments: Working Toward Optimization.
    Journal of speech, language, and hearing research : JSLHR, 2017, 01-01, Volume: 60, Issue:1

    Topics: Adolescent; Algorithms; Auditory Perception; Child; Environment; Hearing Aids; Hearing Loss, Sensorineural; Humans; Patient Preference; Schools; Thiazoles

2017
Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.
    Journal of the American Chemical Society, 2017, 04-26, Volume: 139, Issue:16

    Topics: Crystallography, X-Ray; Models, Molecular; Molecular Structure; Thiazoles

2017
Discrimination of Nosiheptide Sources with Plasmonic Filters.
    ACS applied materials & interfaces, 2017, Apr-19, Volume: 9, Issue:15

    Topics: Filtration; Silver; Spectrum Analysis, Raman; Thiazoles

2017
Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ.
    Nature communications, 2017, 09-05, Volume: 8, Issue:1

    Topics: Bacterial Proteins; Biosynthetic Pathways; Carrier Proteins; Indoles; Kinetics; Protein Binding; Streptomyces; Surface Plasmon Resonance; Thiazoles

2017
Identification of truncated form of NosP as a transcription factor to regulate the biosynthesis of nosiheptide.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Codon, Initiator; Escherichia coli; Gene Deletion; Genes, Bacterial; Genetic Complementation Test; Multigene Family; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Streptomyces; Thiazoles; Transcription Factors

2018
NosN, a Radical S-Adenosylmethionine Methylase, Catalyzes Both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide.
    Journal of the American Chemical Society, 2017, 12-06, Volume: 139, Issue:48

    Topics: Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles

2017
NosP-Regulated Nosiheptide Production Responds to Both Peptidyl and Small-Molecule Ligands Derived from the Precursor Peptide.
    Cell chemical biology, 2018, 02-15, Volume: 25, Issue:2

    Topics: Bacterial Proteins; Ligands; Molecular Conformation; Peptides; Small Molecule Libraries; Streptomyces; Thiazoles

2018
Thiolation Protein-Based Transfer of Indolyl to a Ribosomally Synthesized Polythiazolyl Peptide Intermediate during the Biosynthesis of the Side-Ring System of Nosiheptide.
    Journal of the American Chemical Society, 2017, 12-20, Volume: 139, Issue:50

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Indoles; Molecular Structure; Peptides; Ribosomes; Sulfhydryl Compounds; Thiazoles

2017
A Master Switch in Thiopeptide Biosynthesis.
    Cell chemical biology, 2018, 02-15, Volume: 25, Issue:2

    Topics: Anti-Bacterial Agents; Peptides; Thiazoles

2018
Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL).
    Methods in enzymology, 2018, Volume: 606

    Topics: Biocatalysis; Carbon-Carbon Lyases; Cloning, Molecular; Crystallography, X-Ray; Enzyme Assays; Molecular Structure; Recombinant Proteins; S-Adenosylmethionine; Thiazoles; Tryptophan

2018
Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide.
    Methods in enzymology, 2018, Volume: 606

    Topics: Bacterial Proteins; Biosynthetic Pathways; Enzyme Assays; Methylation; Methyltransferases; Peptides; Recombinant Proteins; S-Adenosylmethionine; Streptomyces; Thiazoles

2018
Rapid determination of nosiheptide in feed based on dispersive SPE coupled with HPLC.
    Journal of separation science, 2019, Volume: 42, Issue:3

    Topics: Chromatography, High Pressure Liquid; Fluorescence; Food Contamination; Molecular Structure; Solid Phase Extraction; Thiazoles

2019
Capturing Intermediates in the Reaction Catalyzed by NosN, a Class C Radical S-Adenosylmethionine Methylase Involved in the Biosynthesis of the Nosiheptide Side-Ring System.
    Journal of the American Chemical Society, 2019, 04-10, Volume: 141, Issue:14

    Topics: Amino Acid Sequence; Biocatalysis; Methyltransferases; S-Adenosylmethionine; Thiazoles

2019
Analysis of Nosiheptide in Food Animal Tissues via Its Unique Degradation Product by Liquid Chromatography-Tandem Mass Spectrometry after Alkaline Hydrolysis.
    Journal of agricultural and food chemistry, 2019, Sep-25, Volume: 67, Issue:38

    Topics: Alkalies; Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Fishes; Food Contamination; Hydrolysis; Limit of Detection; Meat; Muscles; Swine; Tandem Mass Spectrometry; Thiazoles

2019
Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) via Cu
    Angewandte Chemie (International ed. in English), 2021, 02-19, Volume: 60, Issue:8

    Topics: Alanine; Anti-Bacterial Agents; Boronic Acids; Catalysis; Copper; Enterococcus faecalis; Microbial Sensitivity Tests; Nisin; Protein Processing, Post-Translational; Ribosomes; Solubility; Staphylococcus aureus; Thiazoles; Thiostrepton

2021
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study.
    Bioorganic & medicinal chemistry, 2021, 02-01, Volume: 31

    Topics: Alanine; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles

2021
Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue.
    ACS synthetic biology, 2022, 01-21, Volume: 11, Issue:1

    Topics: Biosynthetic Pathways; Multigene Family; Peptides; Thiazoles

2022