thiazoles has been researched along with nosiheptide in 65 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 9 (13.85) | 18.7374 |
1990's | 3 (4.62) | 18.2507 |
2000's | 11 (16.92) | 29.6817 |
2010's | 37 (56.92) | 24.3611 |
2020's | 5 (7.69) | 2.80 |
Authors | Studies |
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Gaillard, C; Moreau, MO; Pascal, C | 1 |
Ducruix, A; Lunel, J; Pascard, C; Prangé, T | 1 |
Dosch, DC; Floss, HG; Li, Y; Strohl, WR; Woodman, RH | 1 |
Alekseeva, LE; Kononovich, TA; Sokolov, LB | 1 |
Dosch, DC; Floss, HG; Li, Y; Strohl, WR | 1 |
Dary, A; Decaris, B; Simonet, B; Simonet, JM | 1 |
Beale, JM; Chen, LC; Floss, HG; Houck, DR; Keller, PJ; Mocek, U | 1 |
Dosch, DC; Floss, HG; Strohl, WR | 1 |
Cromwell, GL; O'Kelly, R; Speer, VC; Stahly, TS | 1 |
Benazet, F; Cartier, JR | 1 |
Cundliffe, E; Thompson, J | 1 |
Benazet, F; Cartier, M; Dubost, M; Florent, J; Godard, C; Jung, G; Lunel, J; Mancy, D; Ninet, L; Pascal, C; Renaut, J; Tarridec, P; Theilleux, J; Tissier, R | 1 |
Aboul-ela, F; Klinck, R; Lentzen, G; Matassova, N; Murchie, AI | 1 |
Bentley, DJ; Fairhurst, J; Gallagher, PT; Manteuffel, AK; Moody, CJ; Pinder, JL | 1 |
Cai, QS; Feng, MQ; Huang, H; Zhou, P | 1 |
Arndt, HD; Lu, JY | 1 |
Kimber, MC; Moody, CJ | 1 |
Bai, L; Fen, M; Shi, X; Zhang, X; Zhou, P | 1 |
Connell, SR; Fucini, P; Harms, JM; Schluenzen, F; Spahn, CM; Stachelhaus, T; Wilson, DN; Zaborowska, Z | 1 |
Cai, Q; Feng, M; Guo, X; Huang, H; Shi, X; Zhou, P | 1 |
Ding, Y; Duan, L; Liao, R; Liu, W; Pan, H; Shen, B; Tang, G; Wendt-Pienkowski, E; Yu, Y; Zhang, Q | 1 |
Arndt, HD; Lu, JY; Mikyna, M; Riedrich, M | 1 |
Chen, DY; Cooperman, BS; Leung, GY; Mikolajka, A; Nicolaou, KC; Qin, H; Schwinghammer, K; Starosta, AL; Wilson, DN | 1 |
Dong, Z; Gong, R; Li, X; Li, Z; Wang, P; Xu, Y; Yang, H; Yang, Y | 1 |
Chen, D; Gong, R; Jia, X; Li, Z; Murchie, AI; Shen, Y; Wang, P; Wang, Z; Xu, Y; Yang, H; Yang, Y; Zhao, L; Zhou, P | 1 |
Ding, Y; Duan, L; Guo, H; Lei, C; Liao, R; Liu, W; Shen, B; Yu, Y; Zhang, Q | 1 |
Chen, D; Duan, L; Li, Y; Liu, W; Shen, B; Yu, Y; Zhang, Q | 1 |
Arcinas, AJ; Booker, SJ | 1 |
Chen, BJ; Chen, CY; Chou, IP; Hsieh, YH; Li, YH; Wang, HT | 1 |
Kelly, WL; Zhang, F | 1 |
Fenical, W; Haste, NM; Hensler, ME; Jensen, PR; Loesgen, S; Nam, SJ; Nizet, V; Sakoulas, G; Sun, P; Thienphrapa, W; Tran, DN | 1 |
Chen, Y; Liu, N; Liu, W; Ma, M; Wang, S; Xue, Y | 2 |
Liu, W; Wang, S; Zhou, S | 1 |
Li, Y; Liang, X; Wang, C; Wang, Q; Zhang, D; Zhang, F | 1 |
Chen, Y; Kong, L; Liu, W; Ma, M; Wang, S; Xue, Y; Zhang, H | 1 |
Liu, X; Shi, X; Zhang, P; Zhou, P; Zhou, W | 1 |
Chen, D; Jiang, H; Murchie, AI; Yin, S | 1 |
Ding, W; Ji, X; Li, Y; Zhang, Q | 1 |
Cao, C; Ding, J; Guo, H; Han, L; Lan, W; Liu, S; Liu, W; Rong, N; Wang, C; Wang, R; Yao, P; Yu, Y; Zhang, T; Zhang, Y | 1 |
Cao, C; Ding, J; Lan, W; Liu, S; Liu, W; Wang, C; Wang, Y; Yao, P; Yu, Y; Zhang, Y | 1 |
Aita, N; Asao, M; Chihara, T; Shimamura, C; Yamata, T | 1 |
Chen, YJ; Jiang, L; Liu, WY; Ma, M; Wang, SZ; Wu, XR; Xue, YJ | 1 |
Liu, Q; Mo, Q; Song, Y; Tang, X; Zan, X; Zhang, H; Zhao, L | 1 |
Chen, Y; Jin, L; Jin, Y; Wang, S; Wu, X; Xue, Y | 1 |
Chen, F; Deng, Z; Ding, W; Ji, X; Li, Y; Mo, T; Qianzhu, H; Tu, T; Yu, Y; Zhang, Q; Zhao, J | 1 |
Galster, J; Picou, EM; Ricketts, TA | 1 |
Badding, ED; Boal, AK; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW | 1 |
Chen, H; Gu, Z; Liu, B; Ni, H; Wang, D; Wang, Z; Zhao, X | 1 |
Deng, Z; Ding, W; Ji, W; Liu, WQ; Ma, X; Mo, T; Tang, B; Wu, R; Wu, Y; Xu, P; Yu, Y; Zhang, Q; Zhang, W; Zhao, J | 1 |
Chen, Y; Jin, L; Ma, M; Tong, R; Wu, X; Zhang, H | 1 |
Badding, ED; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW; Wang, B | 2 |
Guo, H; Li, J; Li, Y; Lin, Z; Liu, W; Niu, G; Qiu, Y; Tan, H | 1 |
Du, Y; Guo, Y; Liao, R; Liu, W; Peng, C; Qiu, Y; Zhang, F; Zhou, S | 1 |
Arndt, HD; Roessler, C | 1 |
Begley, TP; Bhandari, DM; Fedoseyenko, D | 1 |
He, L; Li, X; Song, X; Xie, J; Zhang, M; Zhang, Y | 1 |
Booker, SJ; LaMattina, JW; Marshall, SL; Wang, B | 1 |
Jin, WB; Tang, GL; Wu, S; Xu, YF; Yuan, H | 1 |
He, L; Li, X; Martín-Esteban, A; Qiu, J; Song, X; Su, Y; Xie, J | 1 |
de Vries, RH; Kuipers, OP; Roelfes, G; Viel, JH | 1 |
Chen, H; Fan, Y; Mu, N; Ruan, Z; Wang, S; Wang, W; Zhu, K | 1 |
Chen, Y; Tan, Y; Wang, M | 1 |
Chen, D; Guo, H; Liu, W; Mu, N; Wang, S; Wang, W; Yin, Y; Zhang, E | 1 |
4 review(s) available for thiazoles and nosiheptide
Article | Year |
---|---|
Transcriptional organization and regulation of the nosiheptide resistance gene in Streptomyces actuosus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Molecular Sequence Data; Molecular Structure; Multigene Family; Open Reading Frames; Promoter Regions, Genetic; Restriction Mapping; Streptomyces; Thiazoles; Transcription, Genetic | 1991 |
Opportunities and challenges from current investigations into the biosynthetic logic of nosiheptide-represented thiopeptide antibiotics.
Topics: Anti-Bacterial Agents; Cycloaddition Reaction; Hydrogenation; Thiazoles | 2013 |
Recent advances in HemN-like radical S-adenosyl-l-methionine enzyme-catalyzed reactions.
Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Duocarmycins; Enzymes; Escherichia coli Proteins; Heme; Hydrogen; Methylation; Peptides, Cyclic; Polyketides; Protein Methyltransferases; S-Adenosylmethionine; Thiazoles | 2020 |
Mutasynthesis Generates Antibacterial Benzothiophenic-Containing Nosiheptide Analogues.
Topics: Anti-Bacterial Agents; Thiazoles; Thiophenes | 2022 |
1 trial(s) available for thiazoles and nosiheptide
Article | Year |
---|---|
Albusin B modulates lipid metabolism and increases antioxidant defense in broiler chickens by a proteomic approach.
Topics: Animals; Antioxidants; ATP-Binding Cassette Transporters; Bacteriocins; Chickens; Diet; Dietary Supplements; Down-Regulation; Enzyme Induction; Fatty Acid-Binding Proteins; Female; Gene Expression Profiling; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Jejunum; Lipid Metabolism; Liver; Male; Recombinant Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Thiazoles; Weight Gain | 2013 |
60 other study(ies) available for thiazoles and nosiheptide
Article | Year |
---|---|
Identification of nosiheptide in feeds and detection of residues in animal tissues.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Biological Assay; Chickens; Colorimetry; Fermentation; Swine; Thiazoles; Tissue Distribution | 1979 |
Highly modified cysteine-containing antibiotics. Chemical structure and configuration of nosiheptide.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cysteine; Methods; Molecular Conformation; Thiazoles | 1977 |
[Structure of the chromophore fragment of copsomycin].
Topics: Anti-Bacterial Agents; Hydrolysis; Methyl Ethers; Thiazoles | 1990 |
Nucleotide sequence and transcriptional analysis of the nosiheptide-resistance gene from Streptomyces actuosus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Codon; Drug Resistance, Microbial; Genes, Bacterial; Molecular Sequence Data; Promoter Regions, Genetic; R Factors; Restriction Mapping; Sequence Homology, Nucleic Acid; Streptomyces; Thiazoles; Transcription, Genetic | 1990 |
[Cloning of a nosiheptide-resistant gene from Streptomyces actuosus].
Topics: Anti-Bacterial Agents; DNA Probes; Drug Resistance, Microbial; Genes, Bacterial; Genetic Vectors; Plasmids; Streptomyces; Thiazoles | 1989 |
1H and 13C NMR assignments of the thiopeptide antibiotic nosiheptide.
Topics: Anti-Bacterial Agents; Carbon Isotopes; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Structure; Thiazoles | 1989 |
Molecular cloning of the nosiheptide resistance gene from Streptomyces actuosus ATCC 25421.
Topics: Anti-Bacterial Agents; Blotting, Southern; Cloning, Molecular; DNA Restriction Enzymes; Drug Resistance, Microbial; Genes, Bacterial; Nucleotide Mapping; Plasmids; Streptomyces; Thiazoles | 1988 |
Efficacy of nosiheptide as a growth promotant for growing-finishing swine--a cooperative study.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Body Weight; Female; Food Additives; Male; Swine; Thiazoles | 1984 |
Effect of nosiheptide as a feed additive in chicks on the quantity, duration, prevalence of excretion, and resistance to antibacterial agents of Salmonella typhimurium; on the proportion of Escherichia coli and other coliforms resistant to antibacterial a
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Chickens; Drug Resistance, Microbial; Escherichia coli; Feces; Poultry Diseases; Salmonella Infections; Salmonella Infections, Animal; Salmonella typhimurium; Thiazoles | 1980 |
The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Escherichia coli; Methylation; Pentoses; Peptide Elongation Factors; Ribosomes; Streptomyces; Thiazoles; Thiostrepton | 1981 |
Nosiheptide, a sulfur-containing peptide antibiotic isolated from Streptomyces actuosus 40037.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Bacteria; Chickens; Drug Evaluation, Preclinical; Food Additives; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Streptomyces; Swine; Thiazoles | 1980 |
Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
Topics: Anti-Bacterial Agents; Bacteriocins; Base Sequence; Binding Sites; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Thiazoles; Thiostrepton | 2003 |
Synthesis of the 2,3,4-trisubstituted indole fragments of nosiheptide and glycothiohexide.
Topics: Doxorubicin; Indoles; Lactones; Molecular Structure; Peptides; Thiazoles | 2004 |
[Preparation of nosiheptide liposomes and its inhibitory effect on hepatitics B virus in vitro].
Topics: Antiviral Agents; Cell Line, Tumor; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatoblastoma; Humans; Liposomes; Liver Neoplasms; Particle Size; Thiazoles | 2005 |
Hetero Diels-Alder synthesis of 3-hydroxypyridines: access to the nosiheptide core.
Topics: Catalysis; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Pyridines; Stereoisomerism; Thiazoles | 2007 |
Construction of macrocyclic thiodepsipeptides: synthesis of a nosiheptide 'southern hemisphere' model system.
Topics: Cyclization; Depsipeptides; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Stereoisomerism; Sulfhydryl Compounds; Thiazoles | 2008 |
Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide.
Topics: Cysteine; Gene Expression; Genetic Engineering; Industrial Microbiology; Methionine Adenosyltransferase; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Streptomyces; Thiazoles | 2008 |
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; Binding Sites; Crystallography, X-Ray; Deinococcus; Gene Expression Regulation; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptides; Protein Biosynthesis; Protein Structure, Tertiary; Ribosomal Proteins; Ribosomes; Thiazoles; Thiostrepton | 2008 |
Recombinant high-density lipoprotein complex as a targeting system of nosiheptide to liver cells.
Topics: Animals; Antiviral Agents; Apolipoprotein A-I; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Drug Stability; Feasibility Studies; Hepatitis B virus; Hepatocytes; Lipoproteins, HDL; Liposomes; Male; Microscopy, Electron, Transmission; Particle Size; Rats; Rats, Wistar; Recombinant Proteins; Thiazoles; Tissue Distribution | 2008 |
Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Gene Expression Regulation, Bacterial; Genes, Bacterial; Molecular Sequence Data; Molecular Structure; Multigene Family; Peptide Biosynthesis; Streptomyces; Thiazoles | 2009 |
Aza-Wittig-supported synthesis of the A ring of nosiheptide.
Topics: Anti-Bacterial Agents; Aza Compounds; Stereoisomerism; Thiazoles | 2009 |
Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays.
Topics: Anti-Bacterial Agents; Binding Sites; GTP Phosphohydrolases; Peptide Elongation Factor Tu; Peptides, Cyclic; Prodrugs; Protein Biosynthesis; Ribosomes; Thiazoles; Thiostrepton | 2009 |
Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM.
Topics: Crystallization; Crystallography, X-Ray; Drug Resistance, Bacterial; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiazoles | 2010 |
Crystal structure of the nosiheptide-resistance methyltransferase of Streptomyces actuosus.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Drug Resistance, Bacterial; Methylation; Methyltransferases; Protein Multimerization; RNA; Streptomyces; Substrate Specificity; Thiazoles | 2010 |
NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.
Topics: Amino Acid Sequence; Catalysis; Dealkylation; Molecular Sequence Data; Molecular Structure; Protein Precursors; Serine; Streptomyces; Thiazoles | 2010 |
Radical-mediated enzymatic carbon chain fragmentation-recombination.
Topics: Binding Sites; Carbon; Catalysis; Chromatography, High Pressure Liquid; Free Radicals; Indoles; Peptides; S-Adenosylmethionine; Substrate Specificity; Thiazoles; Time Factors; Tryptophan | 2011 |
Enzymology: Radical break-up, blissful make-up.
Topics: Anti-Bacterial Agents; Catalysis; Enzyme Activation; Enzymes and Coenzymes; Free Radicals; Models, Chemical; S-Adenosylmethionine; Thiazoles; Tryptophan | 2011 |
In vivo production of thiopeptide variants.
Topics: Anti-Bacterial Agents; Genes, Bacterial; Genetic Engineering; Multigene Family; Peptide Biosynthesis; Peptides; Plasmids; Protein Precursors; Ribosomes; Streptomyces; Structure-Activity Relationship; Thiazoles; Thiostrepton | 2012 |
Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Streptomyces; Thiazoles; Time Factors; Vancomycin | 2012 |
The C-terminal extended serine residue is absolutely required in nosiheptide maturation.
Topics: Amides; Amino Acid Sequence; Amino Acids; Serine; Thiazoles | 2013 |
Multiple oxidative routes towards the maturation of nosiheptide.
Topics: Cytochrome P-450 Enzyme System; Molecular Structure; Oxidation-Reduction; Thiazoles | 2013 |
Genome shuffling and ribosome engineering of Streptomyces actuosus for high-yield nosiheptide production.
Topics: Animal Feed; Anti-Bacterial Agents; DNA Shuffling; Fermentation; Food Additives; Genome, Bacterial; Industrial Microbiology; Mutagenesis; Ribosomes; Streptomyces; Thiazoles | 2014 |
Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; Biocatalysis; Escherichia coli; Genetic Vectors; Molecular Sequence Data; Multigene Family; Promoter Regions, Genetic; Protein Binding; Ribosomes; Streptomyces; Thiazoles | 2014 |
Effect analysis of mineral salt concentrations on nosiheptide production by Streptomyces actuosus Z-10 using response surface methodology.
Topics: Culture Media; Fermentation; Minerals; Salts; Streptomyces; Thiazoles | 2014 |
Substrate recognition and modification by the nosiheptide resistance methyltransferase.
Topics: Anti-Bacterial Agents; Binding Sites; Drug Resistance, Bacterial; Enzyme Activation; Methylation; Methyltransferases; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Multimerization; RNA; Substrate Specificity; Thiazoles | 2015 |
Substrate-Tuned Catalysis of the Radical S-Adenosyl-L-Methionine Enzyme NosL Involved in Nosiheptide Biosynthesis.
Topics: Catalysis; Methionine; Molecular Structure; S-Adenosylmethionine; Thiazoles | 2015 |
Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis.
Topics: Amide Synthases; Crystallography, X-Ray; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Thiazoles | 2015 |
Crystallographic analysis of NosA, which catalyzes terminal amide formation in the biosynthesis of nosiheptide.
Topics: Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Gene Expression; Molecular Sequence Data; Peptides; Recombinant Fusion Proteins; Selenomethionine; Sequence Alignment; Streptomyces; Thiazoles | 2015 |
[Validation Study on a Method of Determination of Nosiheptide in Formula Feeds by HPLC-FL].
Topics: Animal Feed; Chromatography, High Pressure Liquid; Food Analysis; Laboratories; Observer Variation; Reproducibility of Results; Thiazoles | 2015 |
The importance of start codon of nosM in nosiheptide production.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Codon, Initiator; Escherichia coli; Genes, Bacterial; Mutation; Streptomyces; Thiazoles | 2015 |
Enhancing nosiheptide production in Streptomyces actuosus by heterologous expression of haemoprotein from Sinorhizobium meliloti.
Topics: Bacterial Proteins; Fermentation; Hemeproteins; Oxygen; Sinorhizobium meliloti; Streptomyces; Thiazoles; Vitreoscilla | 2016 |
Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Genes, Bacterial; Gram-Positive Bacteria; Protein Biosynthesis; Protein Sorting Signals; Streptomyces; Thiazoles | 2017 |
The Catalytic Mechanism of the Class C Radical S-Adenosylmethionine Methyltransferase NosN.
Topics: Anti-Bacterial Agents; Catalysis; Free Radicals; Methylation; Methyltransferases; Molecular Structure; S-Adenosylmethionine; Thiazoles | 2017 |
Directional Microphone Hearing Aids in School Environments: Working Toward Optimization.
Topics: Adolescent; Algorithms; Auditory Perception; Child; Environment; Hearing Aids; Hearing Loss, Sensorineural; Humans; Patient Preference; Schools; Thiazoles | 2017 |
Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK.
Topics: Crystallography, X-Ray; Models, Molecular; Molecular Structure; Thiazoles | 2017 |
Discrimination of Nosiheptide Sources with Plasmonic Filters.
Topics: Filtration; Silver; Spectrum Analysis, Raman; Thiazoles | 2017 |
Biosynthesis of the nosiheptide indole side ring centers on a cryptic carrier protein NosJ.
Topics: Bacterial Proteins; Biosynthetic Pathways; Carrier Proteins; Indoles; Kinetics; Protein Binding; Streptomyces; Surface Plasmon Resonance; Thiazoles | 2017 |
Identification of truncated form of NosP as a transcription factor to regulate the biosynthesis of nosiheptide.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Codon, Initiator; Escherichia coli; Gene Deletion; Genes, Bacterial; Genetic Complementation Test; Multigene Family; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Streptomyces; Thiazoles; Transcription Factors | 2018 |
NosN, a Radical S-Adenosylmethionine Methylase, Catalyzes Both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide.
Topics: Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles | 2017 |
NosP-Regulated Nosiheptide Production Responds to Both Peptidyl and Small-Molecule Ligands Derived from the Precursor Peptide.
Topics: Bacterial Proteins; Ligands; Molecular Conformation; Peptides; Small Molecule Libraries; Streptomyces; Thiazoles | 2018 |
Thiolation Protein-Based Transfer of Indolyl to a Ribosomally Synthesized Polythiazolyl Peptide Intermediate during the Biosynthesis of the Side-Ring System of Nosiheptide.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Indoles; Molecular Structure; Peptides; Ribosomes; Sulfhydryl Compounds; Thiazoles | 2017 |
A Master Switch in Thiopeptide Biosynthesis.
Topics: Anti-Bacterial Agents; Peptides; Thiazoles | 2018 |
Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL).
Topics: Biocatalysis; Carbon-Carbon Lyases; Cloning, Molecular; Crystallography, X-Ray; Enzyme Assays; Molecular Structure; Recombinant Proteins; S-Adenosylmethionine; Thiazoles; Tryptophan | 2018 |
Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide.
Topics: Bacterial Proteins; Biosynthetic Pathways; Enzyme Assays; Methylation; Methyltransferases; Peptides; Recombinant Proteins; S-Adenosylmethionine; Streptomyces; Thiazoles | 2018 |
Rapid determination of nosiheptide in feed based on dispersive SPE coupled with HPLC.
Topics: Chromatography, High Pressure Liquid; Fluorescence; Food Contamination; Molecular Structure; Solid Phase Extraction; Thiazoles | 2019 |
Capturing Intermediates in the Reaction Catalyzed by NosN, a Class C Radical S-Adenosylmethionine Methylase Involved in the Biosynthesis of the Nosiheptide Side-Ring System.
Topics: Amino Acid Sequence; Biocatalysis; Methyltransferases; S-Adenosylmethionine; Thiazoles | 2019 |
Analysis of Nosiheptide in Food Animal Tissues via Its Unique Degradation Product by Liquid Chromatography-Tandem Mass Spectrometry after Alkaline Hydrolysis.
Topics: Alkalies; Animals; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Fishes; Food Contamination; Hydrolysis; Limit of Detection; Meat; Muscles; Swine; Tandem Mass Spectrometry; Thiazoles | 2019 |
Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) via Cu
Topics: Alanine; Anti-Bacterial Agents; Boronic Acids; Catalysis; Copper; Enterococcus faecalis; Microbial Sensitivity Tests; Nisin; Protein Processing, Post-Translational; Ribosomes; Solubility; Staphylococcus aureus; Thiazoles; Thiostrepton | 2021 |
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study.
Topics: Alanine; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2021 |
Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue.
Topics: Biosynthetic Pathways; Multigene Family; Peptides; Thiazoles | 2022 |