thiazoles has been researched along with n,n'-((5-(2-amino-5-(2-methylpropyl)-4-thiazolyl)-2-furanyl)phosphinylidene)bis(alanine) diethyl ester in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dang, Q; Erion, MD; Jiang, T; Kasibhatla, SR; Lipscomb, WN; Potter, SC; Reddy, KR; Reddy, MR; van Poelje, PD | 1 |
| Lu, J; Xie, Z; Zhang, H; Zhang, WJ; Zhang, Y; Zhou, G | 1 |
| Cashion, DK; Dang, Q; DaRe, J; Erion, MD; Fan, Y; Gibson, T; Jacintho, JD; Jiang, T; Kasibhatla, SR; Lemus, R; Li, H; Li, W; Liu, Y; Potter, SC; Sun, Z; Taplin, F; Tian, F; van Poelje, PD | 1 |
| Carrothers, TJ; Habtemariam, B; Kastrissios, H; Khariton, T; Kshirsagar, S; Mager, DE; Rohatagi, S; Walker, JR | 1 |
4 other study(ies) available for thiazoles and n,n'-((5-(2-amino-5-(2-methylpropyl)-4-thiazolyl)-2-furanyl)phosphinylidene)bis(alanine) diethyl ester
| Article | Year |
|---|---|
MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes.
Topics: Adenosine Monophosphate; Alanine; Analysis of Variance; Animals; Carbon Radioisotopes; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Design; Fructose-Bisphosphatase; Gluconeogenesis; Humans; Liver; Male; Molecular Mimicry; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Rats, Zucker; Spectrophotometry; Thiazoles | 2005 |
Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells.
Topics: Alanine; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fructose-Bisphosphatase; Gene Knockdown Techniques; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Organophosphonates; Organophosphorus Compounds; RNA, Small Interfering; Thiazoles; Transfection; Up-Regulation | 2010 |
Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.
Topics: Administration, Oral; Alanine; Amides; Animals; Biological Availability; Blood Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Male; Mice; Organophosphonates; Prodrugs; Protein Binding; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles | 2011 |
Population pharmacokinetic model for a novel oral hypoglycemic formed in vivo: comparing the use of active metabolite data alone versus using data of upstream and downstream metabolites.
Topics: Aged; Alanine; Computer Simulation; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Models, Biological; Molecular Structure; Organophosphonates; Prodrugs; Thiazoles | 2012 |