thiazoles has been researched along with n-methylaspartate in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.38) | 18.7374 |
| 1990's | 13 (30.95) | 18.2507 |
| 2000's | 21 (50.00) | 29.6817 |
| 2010's | 7 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becquet, D; Faudon, M; Hery, F | 1 |
| D'Angio, M; Scatton, B; Serrano, A | 1 |
| Barbeito, L; Estevez, AG; Stutzmann, JM | 1 |
| Delumeau, JC; Doble, A; Glowinski, J; Hubert, JP; Prémont, J | 1 |
| Balázs, R; Boer, GJ; Hack, N; Resink, A | 1 |
| Daniel, M; Doble, A; Malgouris, C | 1 |
| Van der Valk, JB; Vijverberg, HP | 1 |
| Aratake, H; Endo, T; Hasegawa, Y; Kitaguchi, N; Morikawa, A; Ogawa, K; Sugimoto, E | 1 |
| Debonnel, G; Gronier, B | 2 |
| Didriksen, M; Ebert, B; Engesgaard, A; Frølund, B; Jaroszewski, JW; Krogsgaard-Larsen, P; Matzen, L | 1 |
| Goldberg, MP; Handran, SD; Hyrc, K; Rothman, SM | 1 |
| Dreyer, EB; Heng, JE; Lessell, E; Levin, LA; Vorwerk, CK; Zurakowski, D | 1 |
| Cebere, A; Cebers, G; Liljequist, S | 1 |
| Obrenovitch, TP; Urenjak, J | 1 |
| Fisher, M; Schaebitz, W | 1 |
| Rosen, JB; Wallace, KJ | 1 |
| Harkany, T; Horvath, KM; Keijser, J; Luiten, PG; Mulder, J; Nyakas, C; van der Meeberg, EK | 1 |
| Augustin, I; Brose, N; Reim, K; Rhee, JS; Rosenmund, C; Sigler, A | 1 |
| Fujimoto, S; Nagai, K; Nagasawa, K; Nishida, K; Shimohama, S | 1 |
| Chan, HH; Chan, LN; Chang, DC; Han, Y; Lee, NT; Li, M; Li, W; Pi, R; Pu, Y; Sucher, NJ | 1 |
| Malagelada, C; Miñano, A; Rodríguez-Alvarez, J; Xifro, X | 1 |
| Faden, AI; Lea, PM; Movsesyan, VA | 1 |
| Cadet, JL; Chen, J; Deng, X; Errico, S; Freed, WJ; Lee, CT | 1 |
| Fu, AK; Gu, Z; Ip, NY; Jiang, Q; Yan, Z | 1 |
| Baik, EJ; Jung, YS; Kim, SU; Lee, BK; Lee, S; Lee, SH; Moon, CH; Park, HS; Park, S; Yi, KY; Yoo, SE | 1 |
| Bochenski, M; Danysz, W; Kotlinska, J | 1 |
| Cao, JB; Guan, TT; Li, YF; Liu, YQ; Luo, ZP; Wang, HL; Zhang, YZ | 1 |
| Cohen, AS; Geddes-Klein, DM; Meaney, DF; Mesfin, MN; Serbest, G | 1 |
| Chen, Z; Ge, QF; Hu, X; Huang, XJ; Liu, JR; Song, Y; Wang, ML; Wei, EQ; Zhang, WP | 1 |
| Kaasik, A; Klimaviciusa, L; Klusa, V; Safiulina, D; Zharkovsky, A | 1 |
| Anrather, J; Avvedimento, EV; Cicale, M; Cuda, G; Iadecola, C; Paternò, R; Postiglione, A; Ruocco, A; Santillo, M; Serù, R | 1 |
| Arranz, N; Delgado, ME; García, A; Haza, AI; Morales, P; Rafter, J | 1 |
| Choi, H; Hong, JT; Kim, Y; Kim, YB; Lee, K; Ma, Y; Nam, SY; Oh, KW; Yun, SR | 1 |
| Pagani, JH; Rosen, JB | 1 |
| Akaike, H; Akaike, N; Hori, N; Ito, Y; Jang, II; Ogawa, S | 1 |
| Egea, J; Gadotti, VM; López, MG; Martins, DF; Mazzardo-Martins, L; Nascimento, FP; Rosa, AO; Santos, AR | 1 |
| Bamji, SX; Cynader, MS; Guo, A; Jia, W; Tapia, L | 1 |
| Chalimoniuk, M; Cui, J; Ding, S; Gu, Z; He, Y; Lee, JC; Simonyi, A; Sun, AY; Sun, GY; Weisman, GA; Wood, WG | 1 |
| Ashby, MC; Isaac, JT; Matta, JA; Roche, KW; Sanz-Clemente, A | 1 |
| Chaves, C; Declèves, X; Margaill, I; Potin, S; Scherrmann, JM; Yousif, S | 1 |
| Berthiaume, AA; Bussey, TJ; Heath, CJ; Hvoslef-Eide, M; Kim, CH; Mar, AC; Oomen, CA; Romberg, C; Saksida, LM | 1 |
1 review(s) available for thiazoles and n-methylaspartate
| Article | Year |
|---|---|
An overview of acute stroke therapy: past, present, and future.
Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy | 2000 |
41 other study(ies) available for thiazoles and n-methylaspartate
| Article | Year |
|---|---|
In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neurons; Riluzole; Serotonin; Spinal Cord; Synaptic Transmission; Tetrodotoxin; Thiazoles | 1990 |
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles | 1989 |
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Rats; Receptors, Amino Acid; Riluzole; Thiazoles | 1995 |
Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of action.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Cytosol; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GTP-Binding Proteins; Indoles; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Rats; Receptors, Glutamate; Riluzole; Sodium Channels; Spectrometry, Fluorescence; Thiazoles; Veratridine | 1994 |
Growth conditions differentially modulate the vulnerability of developing cerebellar granule cells to excitatory amino acids.
Topics: Animals; Calcium Radioisotopes; Cells, Cultured; Cerebellum; Excitatory Amino Acids; GABA Agonists; GABA Antagonists; Glutamic Acid; Immunohistochemistry; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrazolium Salts; Thiazoles | 1994 |
Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices.
Topics: Animals; Cell Death; Female; Hippocampus; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Nerve Tissue Proteins; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channels; Thiazoles; Veratridine; Virulence Factors, Bordetella | 1994 |
Chronic sabeluzole treatment of cultured rat cerebellar granule cells reduces N-methyl-D-aspartate-induced inward current.
Topics: Animals; Cells, Cultured; Cerebellum; Membrane Potentials; N-Methylaspartate; Piperidines; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thiazoles | 1993 |
A new compound (AZ36041) promotes the survival of the neurons and reduces neurotoxicity of Alzheimer's beta-amyloid protein.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Dizocilpine Maleate; Female; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Sulfonamides; Thiazoles | 1995 |
Electrophysiological evidence for the implication of cholecystokinin in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
Topics: Animals; Cholecystokinin; Cinnamates; Cyclopropanes; Drug Synergism; Electrophysiology; Hippocampus; Hormone Antagonists; Indoleacetic Acids; Male; N-Methylaspartate; Pentazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sincalide; Thiazoles | 1996 |
AMPA receptor agonists: synthesis, protolytic properties, and pharmacology of 3-isothiazolol bioisosteres of glutamic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Glutamic Acid; Mice; N-Methylaspartate; Rats; Receptors, AMPA; Receptors, Kainic Acid; Thiazoles | 1997 |
Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiazoles; Calcium; Cell Death; Coumarins; Dextrans; Excitatory Amino Acid Agonists; Fluorescent Dyes; Forecasting; Fura-2; Intracellular Membranes; Ions; Mice; N-Methylaspartate; Neurons; Neurotoxins; Osmolar Concentration; Thiazoles | 1997 |
Ethambutol is toxic to retinal ganglion cells via an excitotoxic pathway.
Topics: Animals; Antitubercular Agents; Calcium; Carbocyanines; Cell Survival; Dose-Response Relationship, Drug; Ethambutol; Ethylenediamines; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Glutamic Acid; Memantine; Membrane Potentials; Mitochondria; N-Methylaspartate; Rats; Retinal Ganglion Cells; Tetrazolium Salts; Thiazoles | 1999 |
Involvement of sigma receptors in the modulation of the glutamatergic/NMDA neurotransmission in the dopaminergic systems.
Topics: Analgesics, Opioid; Animals; Caudate Nucleus; Cinnamates; Cyclopropanes; Dopamine; Electrophysiology; Excitatory Amino Acids; Glutamic Acid; Guanidines; Kainic Acid; Male; N-Methylaspartate; Neurons; Nucleus Accumbens; Pentazocine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Substantia Nigra; Synaptic Transmission; Thiazoles; Ventral Tegmental Area | 1999 |
Enhancement of NMDA-induced functional responses without concomitant NMDA receptor changes following chronic ethanol exposure in cerebellar granule cells.
Topics: Analysis of Variance; Animals; Apoptosis; Benzothiadiazines; Binding, Competitive; Blotting, Western; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Diuretics; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Intracellular Fluid; Long-Term Potentiation; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride Symporter Inhibitors; Tetrazolium Salts; Thiazoles | 1999 |
Kynurenine 3-hydroxylase inhibition in rats: effects on extracellular kynurenic acid concentration and N-methyl-D-aspartate-induced depolarisation in the striatum.
Topics: Administration, Oral; Animals; Cerebral Cortex; Corpus Striatum; Electroencephalography; Enzyme Inhibitors; Extracellular Space; Injections, Intraperitoneal; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Membrane Potentials; Microdialysis; Mixed Function Oxygenases; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Thiazoles | 2000 |
Neurotoxic lesions of the lateral nucleus of the amygdala decrease conditioned fear but not unconditioned fear of a predator odor: comparison with electrolytic lesions.
Topics: Amygdala; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Conditioning, Classical; Electrolysis; Electroshock; Fear; Male; Memory; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Smell; Thiazoles; Volatilization | 2001 |
Oral post-lesion administration of 5-HT(1A) receptor agonist repinotan hydrochloride (BAY x 3702) attenuates NMDA-induced delayed neuronal death in rat magnocellular nucleus basalis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Administration, Oral; Animals; Apoptosis; Basal Nucleus of Meynert; Behavior, Animal; Benzopyrans; Choline O-Acetyltransferase; Excitatory Amino Acid Agonists; Male; Memory; N-Methylaspartate; Neurons; Neuroprotective Agents; Parietal Lobe; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiazoles | 2001 |
Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultured; Dizocilpine Maleate; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Protein Isoforms; Synaptic Transmission; Synaptic Vesicles; Thiazoles; Thiazolidines; Type C Phospholipases | 2002 |
Differential expression profiles of PLC-beta1 and -delta1 in primary cultured rat cortical neurons treated with N-methyl-D-aspartate and peroxynitrite.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Isoenzymes; N-Methylaspartate; Neurons; Penicillamine; Peroxynitrous Acid; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Type C Phospholipases | 2004 |
Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.
Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Glutamic Acid; Humans; Membrane Potentials; Microscopy, Confocal; Minocycline; N-Methylaspartate; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factors | 2004 |
Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis.
Topics: Animals; Animals, Newborn; Antibodies; Apoptosis; Blotting, Western; Brain-Derived Neurotrophic Factor; Caspase 3; Caspases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Immunohistochemistry; N-Methylaspartate; Neurons; Potassium Chloride; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time; Time Factors | 2005 |
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Etoposide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hydrolysis; Male; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thiazoles | 2005 |
Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death.
Topics: alpha-Tocopherol; Animals; Benzimidazoles; Benzoxazines; Blotting, Northern; Blotting, Western; Calcium Channel Blockers; Calcium Channels; Capsaicin; Cell Count; Cell Death; Cell Lineage; Dizocilpine Maleate; DNA, Single-Stranded; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Excitatory Amino Acid Agonists; Immunohistochemistry; In Situ Nick-End Labeling; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Neuroprotective Agents; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA, Messenger; Ruthenium; Tetrazolium Salts; Thiazoles; TRPC Cation Channels | 2005 |
Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex.
Topics: Animals; Animals, Newborn; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chelating Agents; Cytochalasin D; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neural Inhibition; Neuregulin-1; Neurons; Nucleic Acid Synthesis Inhibitors; Patch-Clamp Techniques; Prefrontal Cortex; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Thiazoles; Thiazolidines | 2005 |
Effects of sabiporide, a specific Na+/H+ exchanger inhibitor, on neuronal cell death and brain ischemia.
Topics: Animals; Brain Infarction; Brain Ischemia; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Glutamic Acid; Guanidines; Mice; N-Methylaspartate; Neurons; Reperfusion; Sodium-Hydrogen Exchangers; Tetrazolium Salts; Thiazoles | 2005 |
N-methyl-D-aspartate and group I metabotropic glutamate receptors are involved in the expression of ethanol-induced sensitization in mice.
Topics: Acamprosate; Alcoholism; Animals; Brain; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Glutamic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Pyridines; Quinolines; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Synaptic Transmission; Taurine; Thiazoles | 2006 |
Inhibition of N-methyl-D-aspartate receptor function appears to be one of the common actions for antidepressants.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Calcium; Calcium Signaling; Cell Survival; Desipramine; Excitatory Amino Acid Antagonists; Fluoxetine; Hippocampus; L-Lactate Dehydrogenase; Moclobemide; Monoamine Oxidase Inhibitors; N-Methylaspartate; Neurons; Nitric Oxide Synthase Type I; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles | 2006 |
Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytosol; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Antagonists; Gene Expression Regulation; N-Methylaspartate; Neurons; Nimodipine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Thiazoles; Thiazolidines | 2006 |
Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation.
Topics: Analysis of Variance; Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flavanones; Immunohistochemistry; Ketamine; Minocycline; N-Methylaspartate; Neuroprotective Agents; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
The effects of glutamate receptor antagonists on cerebellar granule cell survival and development.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; In Situ Nick-End Labeling; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2008 |
Farnesyl transferase inhibitors induce neuroprotection by inhibiting Ha-Ras signalling pathway.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Agonists; Farnesyltranstransferase; Male; Maleates; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
Inhibition by vitamin C of apoptosis induced by N-nitrosamines in HepG2 and HL-60 cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Carcinogens; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme System; Excitatory Amino Acid Agonists; HL-60 Cells; Humans; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Liver Neoplasms; N-Methylaspartate; N-Nitrosopyrrolidine; Nitrosamines; Tetrazolium Salts; Thiazoles | 2008 |
Protective effects of sanjoinine A against N-methyl-D-aspartate-induced seizure.
Topics: Animals; Anticonvulsants; Calcium; Cell Survival; Cells, Cultured; Electroencephalography; Electroshock; Excitatory Amino Acid Agonists; Female; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurons; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Seizures; Tetrazolium Salts; Thiazoles; Ziziphus | 2008 |
The medial hypothalamic defensive circuit and 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) induced fear: comparison of electrolytic and neurotoxic lesions.
Topics: Animals; Electrodes; Excitatory Amino Acid Agonists; Fear; Freezing Reaction, Cataleptic; Hypothalamus, Middle; Ibotenic Acid; Male; N-Methylaspartate; Odorants; Rats; Rats, Sprague-Dawley; Thiazoles | 2009 |
Effects of Z-338, a novel gastroprokinetic agent, on the actions of excitatory and inhibitory neurotransmitters on neurons in area postrema.
Topics: Adenosine Triphosphate; Animals; Area Postrema; Benzamides; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Ganglionic Stimulants; Gastrointestinal Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Patch-Clamp Techniques; Rats; Rats, Wistar; Thiazoles; Vagus Nerve | 2010 |
The antinociceptive effects of AR-A014418, a selective inhibitor of glycogen synthase kinase-3 beta, in mice.
Topics: Abdominal Pain; Aggression; Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Formaldehyde; Glutamic Acid; Glycogen Synthase Kinase 3; Inflammation; Male; Mice; N-Methylaspartate; Pain Measurement; Sugar Acids; Thiazoles; Urea; Xylose | 2011 |
Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures.
Topics: Animals; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation; Granulins; Humans; Hydrogen Peroxide; Indoles; Intercellular Signaling Peptides and Proteins; Mice; N-Methylaspartate; Neurons; Oxidants; Pregnancy; Progranulins; Protein Transport; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
Prolonged exposure of cortical neurons to oligomeric amyloid-β impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Arachidonic Acid; Calcium; Catechin; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug Interactions; Embryo, Mammalian; Glycoproteins; L-Lactate Dehydrogenase; N-Methylaspartate; NADPH Oxidases; Neurons; Neuroprotective Agents; Oxazines; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Xanthenes | 2011 |
mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Electric Stimulation; Enzyme Inhibitors; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Knockout; Models, Biological; N-Methylaspartate; Piperidines; Pyramidal Cells; Pyridines; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thiazoles; Time Factors; Visual Cortex | 2011 |
Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation.
Topics: Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood Vessels; Blood-Brain Barrier; Brain; Cell Line, Transformed; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glutamic Acid; Humans; Iloprost; Male; Meloxicam; Misoprostol; Morphine; N-Methylaspartate; Narcotics; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiazines; Thiazoles; Time Factors | 2012 |
Trial-unique, delayed nonmatching-to-location (TUNL) touchscreen testing for mice: sensitivity to dorsal hippocampal dysfunction.
Topics: Animals; Automation; Choice Behavior; Cognition; Conditioning, Operant; Hippocampus; Male; Meloxicam; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurotoxins; Thiazines; Thiazoles | 2015 |