thiazoles has been researched along with mk-8745 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chowdhury, A; Chowdhury, S; Tsai, MY | 1 |
| Liu, S; Ouchi, T; Saeki, T; Shionome, Y; Yan, L | 1 |
| Durbas, M; Horwacik, I; Nowak, I; Rokita, H; Wiśniewska, A | 1 |
| Almilaibary, A | 1 |
4 other study(ies) available for thiazoles and mk-8745
| Article | Year |
|---|---|
A novel Aurora kinase A inhibitor MK-8745 predicts TPX2 as a therapeutic biomarker in non-Hodgkin lymphoma cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; Aurora Kinase A; Aurora Kinases; Biomarkers; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cyclin B; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Histones; Humans; Lymphoma, Non-Hodgkin; Microtubule-Associated Proteins; Neoplasm Proteins; Nuclear Proteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Thiazoles; Transcription Factors; Xenopus laevis; Xenopus Proteins | 2012 |
Integrity of p53 associated pathways determines induction of apoptosis of tumor cells resistant to Aurora-A kinase inhibitors.
Topics: Animals; Apoptosis; Aurora Kinase A; Aurora Kinases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Female; HCT116 Cells; Humans; Mice; Neoplasms; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiazoles; TOR Serine-Threonine Kinases; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Apoptosis is responsible for the cytotoxic effects of anti-GD2 ganglioside antibodies and aurora A kinase inhibitors on human neuroblastoma cells.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Aurora Kinase A; Caspase 3; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gangliosides; Humans; Mice; Neuroblastoma; Piperazines; Thiazoles | 2022 |
Targeting aurora kinase a (AURKA) in cancer: molecular docking and dynamic simulations of potential AURKA inhibitors.
Topics: Animals; Aurora Kinase A; Cell Line, Tumor; Humans; Mammals; Molecular Docking Simulation; Neoplasms; Piperazines; Serine; Thiazoles; Threonine | 2022 |