Page last updated: 2024-08-21

thiazoles and methotrexate

thiazoles has been researched along with methotrexate in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (20.00)18.2507
2000's17 (42.50)29.6817
2010's14 (35.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Fujimaru, J; Hirabayashi, K; Ogura, M; Takeda, Y; Tomiyoshi, Y; Wada, Y; Yoshida, S1
Haber, M; Madafiglio, J; Norris, MD1
Asaga, T; Kawahara, S; Osawa, Y; Yanoma, S; Yoshida, A1
Degner, FL; Hübner, G; Rau, R; Sander, O; Türck, D1
Black, P; Finkelstein, SD; Hand, CM; Vender, JR1
Damian, MS; Leweke, F; Schachenmayr, W; Schindler, C1
Jansen, G; Kaspers, GJ; Mauritz, R; Noordhuis, P; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ1
Song, S; Tang, Z; Xu, J1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Ohmine, K; Tsunoda, S1
Kang, XT; Li, XH; Xie, RL1
Gao, F; Hirata, K; Horie, T; Sosogi, A; Tomimatsu, T1
Ardito, R; De Santis, V; Falcone, G; Maccauro, G; Muratori, F; Rosa, MA; Sgambato, A1
Blazek, B; Hajduch, M; Janostakova, A; Kouzmina, G; Mihal, V; Noskova, V; Orel, M; Pospisilova, D; Safarova, M; Stary, J1
Deutsch, M; Herman, S; Zurgil, N1
Karasek, M; Kunert-Radek, J; Lawnicka, H; Pawlikowski, M; Winczyk, K1
Hashkes, PJ; Laxer, RM1
Chen, Y; Liu, FY; Liu, XD; Zhang, JL; Zheng, HG1
Das, CM; Gopalakrishnan, V; Prasad, P; Vasquez, H; Wolff, JE1
Beverloo, HB; Cornelissen, JJ; Deenik, W; Valk, PJ; van der Poel-van de Luytgaarde, SC; van Esser, JW; Wattel, MM1
Ahmed, N; Cang, S; Liu, D; Mathews, T; Primanneni, S; Seiter, K; Tan, J1
Bazso, A; Consolaro, A; Filocamo, G; Magni-Manzoni, S; Malattia, C; Martini, A; Pistorio, A; Ravelli, A; Ruperto, N; Viola, S1
Haruta, Y; Hattori, N; Hirata, S; Kohno, N; Kumagai, K; Yokoyama, A1
de Vlam, K; Lories, RJ; Van Tilt, I; Westhovens, R1
Díaz, J; González, A; Mora, C; Quintana, G1
Liu, XD; Ye, LH; Zhang, JL1
Anderson, RJ; Cunningham, A; Donaldson, M; George, SE; Groundwater, PW1
Ji, XY; Niu, BH; Wang, JJ; Xi, Y1
Braddock, M; Clifton, AD; Lopez-Castejon, G; Pelegrin, P; Surprenant, A; Theaker, J1
Bauer, K; Engert, A; Kluge, S; Kreuzer, KA; Monsef, I; Siebert, H; Skoetz, N1
Khagga, M; Thappali, SR; Vakkalanka, SK; Varanasi, KV; Veeraraghavan, S1
Burger, JA; Challagundla, P; Champlin, RE; Cortes, JE; Estrov, Z; Faderl, S; Ferrajoli, A; Garris, R; Huang, X; Jorgensen, JL; Kantarjian, HM; Kebriaei, P; Luthra, R; O'Brien, S; Ravandi, F; Thomas, DA; Wang, SA; Wen, S1
Abruzzo, L; Borthakur, G; Cortes, J; Faderl, S; Jabbour, E; Jorgensen, JL; Kantarjian, H; Konoplev, S; Luthra, R; O'Brien, S; Quintas-Cardama, A; Ravandi, F; Strati, P; Thomas, D1
Lee, SK; Lee, SW; Park, HJ; Park, MC; Park, YB1
Hatta, Y1
Alcocer, S; Bohorquez, D; de Morales, TR; Morón-Medina, A; Viera, N1
Audemard, A; Bergot, E; Chantepie, S; de la Gastine, B; Gac, AC; Reman, O; Verger, H1
Al-Harbi, SA; Al-Saidi, HM; Bashandy, MS; Emara, AAA; Mousa, TAA1
Ando, Y; Hamada, S; Ikuta, K; Ishiguro, N; Kozawa, E; Nishida, Y; Tsukushi, S; Urakawa, H1
Dilek, E; Polat, MF1
Hu, L; Li, Y; Ruan, C; Wang, Q; Wang, S; Ye, M; Zhang, X1

Reviews

3 review(s) available for thiazoles and methotrexate

ArticleYear
Update on the medical treatment of juvenile idiopathic arthritis.
    Current rheumatology reports, 2006, Volume: 8, Issue:6

    Topics: Antibodies, Blocking; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Humans; Immunologic Factors; Infliximab; Isoxazoles; Leflunomide; Meloxicam; Methotrexate; Naproxen; Rheumatology; Thiazines; Thiazoles

2006
t(3;9;22) 3-way chromosome translocation in chronic myeloid leukemia is associated with poor prognosis.
    Cancer investigation, 2009, Volume: 27, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 9; Cyclophosphamide; Dasatinib; Dexamethasone; Disease Progression; Doxorubicin; Drug Resistance, Neoplasm; Fatal Outcome; Humans; Imatinib Mesylate; Karyotyping; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Philadelphia Chromosome; Piperazines; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Rituximab; Thiazoles; Translocation, Genetic; Vincristine

2009
[Acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Dasatinib; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Humans; Imatinib Mesylate; Methotrexate; Middle Aged; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Young Adult

2014

Trials

4 trial(s) available for thiazoles and methotrexate

ArticleYear
Lack of pharmacokinetic interaction of meloxicam with methotrexate in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1997, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Interactions; Female; Humans; Male; Meloxicam; Methotrexate; Middle Aged; Thiazines; Thiazoles

1997
[Methotrexate in conjunction with meloxicam for treating ankylosing spondylitis: a clinical observation of the efficacy and safety].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:5

    Topics: Adult; Drug Therapy, Combination; Humans; Male; Meloxicam; Methotrexate; Prospective Studies; Spondylitis, Ankylosing; Thiazines; Thiazoles

2003
[Clinical randomized study of bee-sting therapy for rheumatoid arthritis].
    Zhen ci yan jiu = Acupuncture research, 2008, Volume: 33, Issue:3

    Topics: Acupuncture Points; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bee Venoms; Female; Humans; Male; Meloxicam; Methotrexate; Middle Aged; Recurrence; Sulfasalazine; Thiazines; Thiazoles

2008
[Effects of wenhua juanbi recipe on TNF-alpha and IL-1beta in peripheral blood of rheumatoid arthritis patients].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2009, Volume: 29, Issue:9

    Topics: Adult; Arthritis, Rheumatoid; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Interleukin-1beta; Male; Meloxicam; Methotrexate; Middle Aged; Phytotherapy; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha; Young Adult

2009

Other Studies

33 other study(ies) available for thiazoles and methotrexate

ArticleYear
[Sensitivity test for anti-tumor agents-3. MTT assay and its clinical effect].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:14

    Topics: Antineoplastic Agents; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Methotrexate; Mitomycin; Ovarian Neoplasms; Predictive Value of Tests; Tetrazolium Salts; Thiazoles; Uterine Neoplasms

1992
Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:6

    Topics: Coloring Agents; Culture Media; Drug Screening Assays, Antitumor; Humans; Leukemia-Lymphoma, Adult T-Cell; Methotrexate; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Tumor Cells, Cultured; Xanthine Oxidase

1993
[In vitro chemosensitivity test for seven undifferentiated thyroid carcinoma cell lines using MTT assay].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Methotrexate; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured; Vincristine

1996
Chemotherapy in experimental brain tumor, part 2: pretreatment with leukotriene C4 prolongs survival.
    Journal of neuro-oncology, 1998, Volume: 36, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Survival; Cisplatin; Colorimetry; Female; Glioma; Leukotriene C4; Male; Methotrexate; Premedication; Rats; Rats, Sprague-Dawley; Survival Analysis; Tetrazolium Salts; Thiazoles

1998
Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein.
    Pathology, research and practice, 1998, Volume: 194, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Immunohistochemistry; Methotrexate; Mitoxantrone; Nimustine; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1998
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Blood, 1999, Feb-01, Volume: 93, Issue:3

    Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; HL-60 Cells; Humans; Infant; Infant, Newborn; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; U937 Cells

1999
[Predictive chemotherapy of breast cancer directed by MTT assay in vitro].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Tetrazolium Salts; Thiazoles

1997
Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro.
    Leukemia, 2002, Volume: 16, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Methotrexate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2002
Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.
    Life sciences, 2003, Jun-13, Volume: 73, Issue:4

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Coloring Agents; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flufenamic Acid; Hydrogen-Ion Concentration; Indomethacin; Intestine, Small; Intestines; Methotrexate; Phosphorylation; Rats; Tetrazolium Salts; Thiazoles; Time Factors

2003
Acrylic cement added with antiblastics in the treatment of bone metastases. Ultrastructural and in vitro analysis.
    The Journal of bone and joint surgery. British volume, 2003, Volume: 85, Issue:5

    Topics: Antineoplastic Agents; Bone Cements; Bone Neoplasms; Cell Division; Cell Survival; Cisplatin; Coloring Agents; Doxorubicin; Drug Carriers; Humans; Methotrexate; Methylmethacrylate; Microscopy, Electron, Scanning; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

2003
The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol.
    Bulletin du cancer, 2004, Volume: 91, Issue:4

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Coloring Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; In Vitro Techniques; Male; Mercaptopurine; Methotrexate; Multivariate Analysis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Predictive Value of Tests; Prednisone; Remission Induction; Sex Factors; Tetrazolium Salts; Thiazoles; Vincristine

2004
Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54, Issue:7

    Topics: Acetylcysteine; Annexin A5; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Arthritis, Rheumatoid; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Immunosuppressive Agents; Jurkat Cells; Leukocytes; Methotrexate; Monocytes; Oxidative Stress; Propidium; Reactive Oxygen Species; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors; U937 Cells

2005
Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells.
    Neuro endocrinology letters, 2006, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Melatonin; Methotrexate; Mice; Nuclear Receptor Subfamily 1, Group F, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Statistics, Nonparametric; Thiazoles; Thiosemicarbazones

2006
Histone acetylation resulting in resistance to methotrexate in choroid plexus cells.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Acetylation; Animals; Antigens, Viral, Tumor; Apoptosis; Benzamides; Carcinoma; Cell Line, Transformed; Cell Line, Tumor; Choroid Plexus; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Gamma Rays; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Inhibitory Concentration 50; Methotrexate; Mice; Pyridines; Tetrazolium Salts; Thiazoles; Valproic Acid

2009
Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia.
    Leukemia, 2009, Volume: 23, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine; Dasatinib; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; In Situ Hybridization, Fluorescence; Male; Methotrexate; Mitoxantrone; Neoplasm Proteins; Neutropenia; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pyrimidines; Remission Induction; Splenic Rupture; Thiazoles; Vincristine; Young Adult

2009
Development and validation of a composite disease activity score for juvenile idiopathic arthritis.
    Arthritis and rheumatism, 2009, May-15, Volume: 61, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Blood Sedimentation; Child; Child, Preschool; Cross-Sectional Studies; Disability Evaluation; Humans; Joints; Meloxicam; Methotrexate; Naproxen; Outcome Assessment, Health Care; Prognosis; Severity of Illness Index; Thiazines; Thiazoles; Treatment Outcome

2009
Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis.
    Clinica chimica acta; international journal of clinical chemistry, 2009, Volume: 407, Issue:1-2

    Topics: Arthritis, Rheumatoid; Case-Control Studies; Cell Proliferation; Humans; Lymphocyte Activation; Methotrexate; Pneumonia; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Time Factors

2009
Unusual cervical spine involvement in psoriatic arthritis: a case series.
    Clinical rheumatology, 2009, Volume: 28, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriatic; Cervical Vertebrae; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Male; Meloxicam; Methotrexate; Middle Aged; Neck Pain; Orthopedic Fixation Devices; Range of Motion, Articular; Spondylarthritis; Spondylitis, Ankylosing; Thiazines; Thiazoles; Tramadol

2009
[Financial cost of early rheumatoid arthritis in the first year of medical attention: three clinical scenarios in a third-tier university hospital in Colombia].
    Biomedica : revista del Instituto Nacional de Salud, 2009, Volume: 29, Issue:1

    Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Protocols; Colombia; Diagnostic Services; Direct Service Costs; Disease Management; Drug Costs; Drug Therapy, Combination; Etanercept; Health Care Costs; Hospital Costs; Hospitals, University; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Meloxicam; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Thiazines; Thiazoles

2009
Evaluation of a range of anti-proliferative assays for the preclinical screening of anti-psoriatic drugs: a comparison of colorimetric and fluorimetric assays with the thymidine incorporation assay.
    Assay and drug development technologies, 2010, Volume: 8, Issue:3

    Topics: Anthralin; Anti-Infective Agents, Local; Caspase 3; Caspase 7; Cell Line; Cell Proliferation; Colorimetry; Dermatologic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; Fluorometry; Humans; Keratinocytes; Methotrexate; Psoriasis; Reproducibility of Results; Tetrazolium Salts; Thiazoles; Thymidine

2010
The establishment and characterization of adriamycin-resistant cell lines derived from Saos-2.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Inhibitory Concentration 50; Methotrexate; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles

2010
P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Aug-15, Volume: 185, Issue:4

    Topics: Adenosine Triphosphate; Animals; Blotting, Western; Cathepsin B; Cathepsins; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukin-1beta; Joint Diseases; L Cells; Macrophages; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Receptors, Tumor Necrosis Factor; Thiazoles

2010
Twelfth biannual report of the Cochrane Haematological Malignancies Group--focus on tyrosine kinase inhibitors.
    Journal of the National Cancer Institute, 2011, Feb-16, Volume: 103, Issue:4

    Topics: Adrenal Cortex Hormones; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Dasatinib; Diphosphonates; Disease-Free Survival; Epoetin Alfa; Erythropoietin; Evidence-Based Medicine; Gemtuzumab; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Randomized Controlled Trials as Topic; Recombinant Proteins; Rituximab; Stem Cell Transplantation; Thiazoles; Treatment Outcome; Vidarabine

2011
Simultaneous determination of methotrexate, dasatinib and its active metabolite N- deshydroxyethyl dasatinib in rat plasma by LC-MS/MS: method validation and application to pharmacokinetic study.
    Arzneimittel-Forschung, 2012, Volume: 62, Issue:12

    Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Dasatinib; Drug Interactions; Half-Life; Indicators and Reagents; Male; Methotrexate; Protein Kinase Inhibitors; Pyrimidines; Quality Control; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry; Thiazoles

2012
Detection of MRD may predict the outcome of patients with Philadelphia chromosome-positive ALL treated with tyrosine kinase inhibitors plus chemotherapy.
    Blood, 2013, Aug-15, Volume: 122, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Flow Cytometry; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunoglobulin Heavy Chains; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm, Residual; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Pyrimidines; Real-Time Polymerase Chain Reaction; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Thiazoles; Vincristine; Young Adult

2013
HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia.
    Cancer, 2014, Feb-01, Volume: 120, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Piperazines; Pyrimidines; Thiazoles; Vincristine

2014
The concomitant use of meloxicam and methotrexate does not clearly increase the risk of silent kidney and liver damages in patients with rheumatoid arthritis.
    Rheumatology international, 2014, Volume: 34, Issue:6

    Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Asymptomatic Diseases; Chemical and Drug Induced Liver Injury; Cohort Studies; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Humans; Liver; Male; Meloxicam; Methotrexate; Middle Aged; Odds Ratio; Prospective Studies; Thiazines; Thiazoles

2014
[Methotrexate as inducer of proinflammatory cytokines by epithelial cells].
    Investigacion clinica, 2014, Volume: 55, Issue:1

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Laryngeal Neoplasms; Methotrexate; Stomatitis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha

2014
[Dasatinib-related pneumonia? An example of pharmacovigilance survey].
    Revue des maladies respiratoires, 2015, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cyclophosphamide; Cytarabine; Dasatinib; Dexamethasone; Doxorubicin; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Pharmacovigilance; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Recombinant Proteins; Thiazoles; Tomography, X-Ray Computed; Vincristine

2015
Synthesis, spectroscopic properties, molecular docking, anti-colon cancer and anti-microbial studies of some novel metal complexes for 2-amino-4-phenylthiazole derivative.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Jun-15, Volume: 145

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Catalytic Domain; Cell Death; Chlorocebus aethiops; Colonic Neoplasms; Coordination Complexes; Electron Spin Resonance Spectroscopy; Electrons; Fungi; HCT116 Cells; Humans; Ligands; Mass Spectrometry; Metals; Methotrexate; Microbial Sensitivity Tests; Molecular Docking Simulation; Proton Magnetic Resonance Spectroscopy; Schiff Bases; Spectrophotometry, Infrared; Tetrahydrofolate Dehydrogenase; Thermogravimetry; Thiazoles; Vero Cells; Vibration

2015
Low-dose chemotherapy with methotrexate and vinblastine for patients with desmoid tumors: relationship to CTNNB1 mutation status.
    International journal of clinical oncology, 2015, Volume: 20, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; beta Catenin; Child; Cyclooxygenase 2 Inhibitors; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fibromatosis, Abdominal; Humans; Male; Meloxicam; Methotrexate; Middle Aged; Mutation; Retreatment; Thiazines; Thiazoles; Vinblastine; Young Adult

2015
In Vitro Inhibition Of Three Different Drugs Used In Rheumatoid Arthritis Treatment On Human Serum Paraoxanase 1 Enzyme Activity.
    Protein and peptide letters, 2016, Volume: 23, Issue:1

    Topics: Antirheumatic Agents; Aryldialkylphosphatase; Catalytic Domain; Dose-Response Relationship, Drug; Humans; Ibuprofen; In Vitro Techniques; Meloxicam; Methotrexate; Thiazines; Thiazoles

2016
Solvent-Induced Protein Precipitation for Drug Target Discovery on the Proteomic Scale.
    Analytical chemistry, 2020, 01-07, Volume: 92, Issue:1

    Topics: Acetic Acid; Acetone; Cells, Cultured; Drug Discovery; Drug Evaluation, Preclinical; Ethanol; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; HSP90 Heat-Shock Proteins; Humans; Methotrexate; NADH Dehydrogenase; Oxazoles; Proteomics; Solvents; Staurosporine; Thiazoles

2020