Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and melagatran

thiazoles has been researched along with melagatran in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Fukuda, T; Furugohri, T; Kita, A; Morishima, Y; Shibano, T; Tsuji, N1
Morishima, Y; Shibano, T; Shirasaki, Y1
Furugohri, T; Morishima, Y1
Honda, Y; Kamisato, C; Morishima, Y1

Other Studies

4 other study(ies) available for thiazoles and melagatran

ArticleYear
Melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, nor heparin aggravates tissue factor-induced hypercoagulation in rats.
    European journal of pharmacology, 2012, Jul-05, Volume: 686, Issue:1-3

    Topics: Animals; Antithrombins; Azetidines; Benzylamines; Blood Coagulation Disorders; Factor Xa Inhibitors; Heparin; Male; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboplastin

2012
Comparison of the effect of edoxaban, a direct factor Xa inhibitor, with a direct thrombin inhibitor, melagatran, and heparin on intracerebral hemorrhage induced by collagenase in rats.
    Thrombosis research, 2014, Volume: 133, Issue:4

    Topics: Animals; Anticoagulants; Antithrombins; Azetidines; Benzylamines; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Factor Xa Inhibitors; Heparin; Male; Pyridines; Rats; Rats, Wistar; Thiazoles

2014
Paradoxical enhancement of the intrinsic pathway-induced thrombin generation in human plasma by melagatran, a direct thrombin inhibitor, but not edoxaban, a direct factor Xa inhibitor, or heparin.
    Thrombosis research, 2015, Volume: 136, Issue:3

    Topics: Anticoagulants; Antithrombins; Azetidines; Benzylamines; Blood Coagulation; Dose-Response Relationship, Drug; Drug Synergism; Factor Xa Inhibitors; Heparin; Humans; Pyridines; Thiazoles; Thrombin; Thromboplastin

2015
Prolongation of clot lysis time by a direct thrombin inhibitor melagatran mediated by paradoxical enhancement of thrombin generation: comparison with a direct factor Xa inhibitor edoxaban.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Apr-01, Volume: 32, Issue:3

    Topics: Antithrombins; Azetidines; Benzylamines; Factor Xa Inhibitors; Fibrin Clot Lysis Time; Fibrinolysis; Humans; Pyridines; Thiazoles; Thrombin

2021