thiazoles has been researched along with mcc-555 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eckel, J; Ishii, S; Liu, LS; Tanaka, H | 1 |
| Bailey, ST; Ishii, S; Krakow, SL; Lazar, MA; Minami, C; Reginato, MJ; Tanaka, H | 1 |
| Ishii, S; King, P; Pickavance, L; Tanaka, H; Widdowson, PS; Williams, G | 1 |
| Chakrabarti, R; Kumar, TD; Madhusudhan, G; Prabhakar, C; Rajagopalan, R; Rao, CS; Reddy, CM; Reddy, GO; Sahadev, K; Sarma, MR | 1 |
| Ishii, S; Tanaka, H; Upton, R; Widdowson, PS; Williams, G | 1 |
| Kadowaki, T | 1 |
| Yamanouchi, T | 1 |
| Foster, JR; Pickavance, LC; Widdowson, PS; Wilding, JP; Williams, G | 1 |
| Cohen, FJ; Gui, D; Ikezoe, T; Koeffler, HP; Kumagai, T; O'Kelly, J; Said, JW; Tong, XJ | 1 |
| Brüne, B; Loitsch, S; Stein, J; Ulrich, S; von Knethen, A; Wächtershäuser, A | 1 |
| Ishii, S; Kasayama, S; Kouhara, H; Kurebayashi, S; Shiraishi, M; Xu, X | 1 |
| Lazarenko, OP; Lecka-Czernik, B; Rzonca, SO; Suva, LJ | 1 |
| Fan, G; Hong, Z; Lin, M; Lu, G; Sun, N | 1 |
| Baek, SJ; Eling, TE; Lee, SH; Yamaguchi, K | 1 |
2 review(s) available for thiazoles and mcc-555
| Article | Year |
|---|---|
[Insulin-sensitizing agents].
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Isoxazoles; Pioglitazone; Rosiglitazone; Thiazoles; Thiazolidinediones | 1999 |
[KRP-297, MCC-555].
Topics: Animals; Clinical Trials, Phase II as Topic; Diabetes Mellitus; Glucose; Humans; Hypoglycemic Agents; Lipid Metabolism; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors | 2001 |
12 other study(ies) available for thiazoles and mcc-555
| Article | Year |
|---|---|
The new antidiabetic drug MCC-555 acutely sensitizes insulin signaling in isolated cardiomyocytes.
Topics: Animals; Blotting, Western; Glucose; Heart; Hypoglycemic Agents; Insulin; Male; Myocardium; Obesity; Phosphatidylinositol 3-Kinases; Precipitin Tests; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Rats, Zucker; Signal Transduction; Thiazoles; Thiazolidinediones | 1998 |
A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor gamma-activating properties.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; Gene Expression Regulation; Hypoglycemic Agents; Insulin Resistance; Male; Mice; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Thiazoles; Thiazolidinediones; Transcription Factors | 1998 |
The development of overt diabetes in young Zucker Diabetic Fatty (ZDF) rats and the effects of chronic MCC-555 treatment.
Topics: Age Factors; Animals; Body Weight; Diabetes Mellitus, Type 2; Drinking; Glucose; Glucose Intolerance; Hypoglycemic Agents; Male; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Time Factors | 1998 |
Synthesis and biological activity of novel thiazolidinediones.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Butanones; Chromans; Edema; Female; Hypoglycemic Agents; Male; Mice; Nabumetone; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazoles; Thiazolidinediones; Troglitazone | 1998 |
Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC-555.
Topics: Animals; Basal Metabolism; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fatty Acids; Hypoglycemic Agents; Insulin; Insulin Resistance; Liver Glycogen; Male; Obesity; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones; Treatment Outcome; Triglycerides | 1998 |
Chronic treatment with the thiazolidinedione, MCC-555, is associated with reductions in nitric oxide synthase activity and beta-cell apoptosis in the pancreas of the Zucker Diabetic Fatty rat.
Topics: Animals; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Administration Schedule; Insulin; Islets of Langerhans; Male; Nitric Oxide Synthase; Rats; Rats, Zucker; Thiazoles; Thiazolidinediones | 2003 |
RWJ-241947 (MCC-555), a unique peroxisome proliferator-activated receptor-gamma ligand with antitumor activity against human prostate cancer in vitro and in beige/nude/ X-linked immunodeficient mice and enhancement of apoptosis in myeloma cells induced by
Topics: Agar; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Caspases; CD36 Antigens; Cell Cycle; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Survival; Genetic Linkage; Humans; Immunologic Deficiency Syndromes; Ligands; Luciferases; Male; Mice; Multiple Myeloma; Oxides; Prostatic Neoplasms; Receptors, Cytoplasmic and Nuclear; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transfection; U937 Cells; X Chromosome | 2004 |
Activation of PPARgamma is not involved in butyrate-induced epithelial cell differentiation.
Topics: Alkaline Phosphatase; Apoptosis; Butyrates; Caco-2 Cells; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Epithelial Cells; Humans; PPAR gamma; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones | 2005 |
A novel thiazolidinedione MCC-555 down-regulates tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1 in vascular endothelial cells.
Topics: Aorta; Cell Adhesion; Down-Regulation; Endothelium, Vascular; Gene Expression; Humans; Hypoglycemic Agents; Insulin Resistance; NF-kappa B; PPAR alpha; PPAR gamma; Promoter Regions, Genetic; Thiazoles; Thiazolidinediones; Tumor Necrosis Factor-alpha; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2005 |
Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat.
Topics: Adipocytes; Animals; Bone Density; Bone Marrow Cells; Cell Culture Techniques; Cell Differentiation; Cell Line; Culture Media; Dose-Response Relationship, Drug; Gene Expression Regulation; Genetic Markers; Ligands; Male; Mice; Mice, Inbred C57BL; Osteoblasts; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazoles; Thiazolidinediones; Tomography, X-Ray Computed | 2006 |
Quantitative determination of MCC-555, a novel insulin sensitizer in beagle dog plasma by high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Female; Hypoglycemic Agents; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Thiazoles; Thiazolidinediones | 2006 |
A novel peroxisome proliferator-activated receptor gamma ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells.
Topics: 3' Untranslated Regions; Antineoplastic Agents; Apoptosis; Base Sequence; Colorectal Neoplasms; Cytokines; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HCT116 Cells; Humans; Ligands; Molecular Sequence Data; PPAR gamma; RNA, Messenger; Thiazoles; Thiazolidinediones; Tumor Cells, Cultured; Up-Regulation | 2006 |