Page last updated: 2024-08-21

thiazoles and lysine

thiazoles has been researched along with lysine in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199010 (15.15)18.7374
1990's11 (16.67)18.2507
2000's33 (50.00)29.6817
2010's12 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Axelrud-Cavadore, C; Coletti-Previero, MA1
Guyer, RL; Lovins, RE; Schnute, WC; Todd, CW1
Alburn, HE; Dougherty, JA; Fenichel, RL1
Freedman, MH; Lyerla, JR1
Nakamura, M; Nakata, T; Nose, Y1
Delduce, AJ; Schwartz, MA1
Fairwell, T; Lovins, RE1
Cortijo, M; Shaltiel, S1
Kovaliv, IuD; Turkevich, BM1
Fasold, H; Gärtner, EM; Legrum, B; Passow, H; Ruffing, W; Zaki, L1
Ansorge, S; Kähne, T; Neubert, K1
Ansorge, S; Bank, U; Bühling, F; Faust, J; Kähne, T; Kunt, D; Neubert, K; Reinhold, D1
Cummins, VP; Kaunitz, JD; Mishler, D; Nagami, GT1
Oettmeier, W; Rutherford, WA; Sopp, G1
Horikawa, H; Kawashima, K; Murakami, T; Sugita, T; Sugiura, M; Tanaka, S1
Ansorge, S; Bank, U; Born, I; Bühling, F; Faust, J; Neubert, K; Reinhold, D; Täger, M1
Ansorge, S; Born, I; Bühling, F; Faust, J; Gollnick, H; Lendeckel, U; Mnich, K; Neubert, K; Reinhold, D; Vetter, RW1
Ansorge, S; Born, I; Faust, J; Gran, B; Hemmer, B; Martin, R; McFarland, HF; Neubert, K; Reinhold, D1
Giordano, H; Liang, L; Peterson, MG; Sivaraja, M; Spector, FC1
Carrasquillo, JA; Green, MV; Jeong, KS; Kim, IS; Kim, MK; Kobayashi, H; Paik, CH; Seidel, J; Soh, Y; Song, BJ1
Ansorge, S; Faust, J; Kähne, T; Neubert, K1
Ansorge, S; Arndt, M; Faust, J; Lendeckel, U; Neubert, K; Reinhold, D; Spiess, A2
Ansorge, S; Born, I; Brocke, S; Faust, J; Gado, A; Izikson, L; Martin, R; Neubert, K; Quigley, L; Reinhold, D; Steinbrecher, A; Tresser, N1
Ansorge, S; Born, I; Brocke, S; Faust, J; Gran, B; Hemmer, B; Kähne, T; Martin, R; Neubert, K; Reinhold, D; Steinbrecher, A; Wrenger, S1
Ansorge, S; Born, I; Bühling, F; Faust, J; Gollnick, H; Lendeckel, U; Neubert, K; Reinhold, D; Vetter, R1
Bakala, H; Depreux, P; Fourmaintraux, E; Schwedler, SB; Striker, GE; Striker, LJ; Verbeke, P; Vilar, J; Weiss, MF1
Hutchinson, I; Jennings, SA; Stevens, MF; Vishnuvajjala, BR; Westwell, AD1
Hu, WW; Young, TH1
Becker, D; Brand, P; Knop, J; Valk, E; Zahn, S1
Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC1
Fink, AL; Han, S; Kaylor, J; Rajamani, S; Zhou, F; Zhu, M1
Alvarez-Sánchez, R; Basketter, D; Dell, A; Divkovic, M; Lepoittevin, JP; Morris, H; Panico, M; Pease, C1
Bauer, R; Corlin, DB; Heegaard, NH; Jørgensen, TJ; Nissen, MH; Pedersen, JS; Roepstorff, P; Rozlosnik, N; Tempesta, AG1
Almeida, FC; Ferrão-Gonzales, AD; Ferreira, A; Foguel, D; Juliano, L; Moreau, VH; Robbs, BK; Silva, JL; Valente, AP1
Infante, MR; Mitjans, M; Sanchez, L; Vinardell, MP2
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, N1
Bacher, J; Groll, AH; Kelaher, A; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, A; Walsh, TJ; Wuerthwein, G1
Brahmachari, S; Fung, YK; Pahan, K1
Faust, J; Friedrich, D; Hartig, R; Hoffmann, T; Kähne, T; Lendeckel, U; Neubert, K; Reinhold, D; Thielitz, A; Wrenger, S1
Basgen, J; Brem, H; Cai, W; Li, Z; Peppa, M; Uribarri, J; Vlassara, H; Zhang, JG1
Arnstein, M; Cooper, ME; Coughlan, MT; Forbes, JM; Gasser, A; Long, DM; Pete, J; Thallas-Bonke, V; Thorpe, SR; Tong, DC1
Ansorge, S; Bank, U; Biton, A; Brocke, S; Faust, J; Lendeckel, U; Neubert, K; Pieper, S; Reinhold, D; Täger, M1
Ji, J; Li, X; Pu, M; Shen, J; Wang, X1
Ansorge, S; Faust, J; Gollnick, HP; Lindenlaub, P; Neubert, K; Reinhold, D; Schultze, B; Simeoni, L; Thielitz, A; Vetter, RW; Wrenger, S1
Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J1
Gu, Z; He, B; Li, L; Luo, K; Nie, Y; Shi, S; Yang, J; Yang, Y; Zhu, R1
Meyer, DM; Mills, LD; Mohammed, SF; Owan, TE; Redfield, MM; Schalkwijk, CG; Shapiro, BP1
Burner, T; Gohr, CM; Mitton, E; Monnier, V; Rosenthal, AK1
Hartog, JW; Voors, AA; Willemsen, S1
Meredith, SC; Orgel, JP; Sciarretta, KL; Tycko, R1
Ansorge, S; Bank, U; Brocke, S; Faust, J; Goihl, A; Kühlmann, UC; Neubert, K; Reinhold, A; Reinhold, D; Täger, M; Thielitz, A; Wrenger, S1
Allen, AD; Cao, WG; Chen, J; Jarvi, MT; Liu, Y; Lovell, JF; Tidwell, TT; Wilson, BC; Zheng, G1
Ansorge, S; Bank, U; Biton, A; Brocke, S; Reinhold, D; Täger, M1
Bassan, R; Bussini, A; Castagnetti, F; Gnani, A; Intermesoli, T; Rosti, G; Soverini, S; Spinelli, O1
Barré, P; Eliezer, D; Huster, D; Künze, G; Scheidt, HA; Thomas, L1
Behrsing, HP; Davis, M; Furniss, MJ; Parchment, RE; Tomaszewski, JE1
Campos-Peña, V; Figueroa-Corona, Mdel P; García-Gutiérrez, P; Lira-De León, KI; Meraz-Ríos, MA; Palomera-Cárdenas, M; Serratos, IN1
Feng, L; Jia, XB; Zhang, MH; Zhu, MM1
Choe, D; Park, HW; Shin, CS; Youn, SH1
André-Frei, V; Bechetoille, N; Berthod, F; Cadau, S; Leoty-Okombi, S; Pain, S1
Ng, YK; Ong, WY; Tan, CS1
Galleano, I; Jung, M; Madsen, AS; Olsen, CA; Schiedel, M1
Berl, V; Debeuckelaere, C; Elbayed, K; Giménez-Arnau, E; Lepoittevin, JP; Moussallieh, FM; Namer, IJ1
Azami-Movahed, M; Ebrahim-Habibi, A; Ghasemi, A; Meratan, AA; Nemat-Gorgani, M1

Reviews

1 review(s) available for thiazoles and lysine

ArticleYear
Anion transport across the red blood cell membrane and the conformation of the protein in Band 3.
    Annals of the New York Academy of Sciences, 1980, Volume: 341

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anion Exchange Protein 1, Erythrocyte; Anions; Benzothiazoles; Binding Sites; Biological Transport, Active; Blood Proteins; Chemical Phenomena; Chemistry; Erythrocyte Membrane; Erythrocytes; Humans; Lysine; Membrane Proteins; Models, Biological; Protein Conformation; Structure-Activity Relationship; Thiazoles

1980

Other Studies

65 other study(ies) available for thiazoles and lysine

ArticleYear
Changes of substrate configuration during trypsin hydrolysis of arginine and lysine 2-phenyl-thiazol-5-ones.
    Biochemical and biophysical research communications, 1975, Feb-17, Volume: 62, Issue:4

    Topics: Arginine; Kinetics; Lysine; Molecular Conformation; Optical Rotation; Protein Binding; Stereoisomerism; Thiazoles; Trypsin

1975
The removal of contaminating quadrol by boric acid extraction prior to mass spectralanalysis of amino acid thiazolinones.
    Analytical biochemistry, 1975, Volume: 66, Issue:2

    Topics: Amino Acids; Aniline Compounds; Boric Acids; Ethylenediamines; Lysine; Mass Spectrometry; Methods; Phenylalanine; Serine; Thiazoles; Threonine

1975
Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid (Wy-23,049)--comparison with acetylsalicylic acid.
    Biochemical pharmacology, 1974, Dec-01, Volume: 23, Issue:23

    Topics: Acrylates; Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Chlorobenzenes; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Lysine; Platelet Adhesiveness; Platelet Aggregation; Polymers; Prostaglandins; Rats; Rats, Inbred Strains; Thiazoles; Time Factors

1974
Spectral assignment and conformational analysis of cyclic peptides by carbon-13 nuclear magnetic resonance.
    The Journal of biological chemistry, 1972, Dec-25, Volume: 247, Issue:24

    Topics: Amino Acids; Bacitracin; Carbon Isotopes; Chemical Phenomena; Chemistry; Computers; Fourier Analysis; Hydrogen-Ion Concentration; Isoleucine; Lysine; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxytocin; Peptides, Cyclic; Protein Conformation; Thiazoles; Vasopressins

1972
Effect of aliphatic amino acids and citric acid cycle compounds on early thiamine production by thiazoleless mutant of Escherichia coli.
    The Journal of vitaminology, 1968, Sep-10, Volume: 14, Issue:3

    Topics: Alanine; Amino Acids; Ammonium Chloride; Aspartic Acid; Carbon Isotopes; Culture Media; Dicarboxylic Acids; Escherichia coli; Formates; Fumarates; Glucose; Glutamates; Lysine; Malates; Mutation; Pyruvates; Serine; Succinates; Thiamine; Thiazoles; Valine

1968
Kinetic analysis of penicilloic acid and penicilloamides in combinattion: application to products of reaction of penicillin with tromethamine (tris) and poly-L-lysine.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:9

    Topics: Amides; Kinetics; Lysine; Methicillin; Methods; Oxacillin; Penicillin G; Penicillin V; Penicillins; Spectrophotometry; Thiazoles; Tromethamine; Ultraviolet Rays

1969
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
    Biochemical and biophysical research communications, 1971, Jun-18, Volume: 43, Issue:6

    Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine

1971
The mode of binding of pyridoxal 5'-phosphate in glycogen phosphorylase.
    Biochemical and biophysical research communications, 1970, Nov-09, Volume: 41, Issue:3

    Topics: Amines; Animals; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Cysteamine; Fluorescence; Glucosyltransferases; Glycogen; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Models, Structural; Muscles; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Thiazoles

1970
[Synthesis of rhodanines on the basis of lysines].
    Farmatsevtychnyi zhurnal, 1966, Volume: 21, Issue:4

    Topics: Lysine; Thiazoles

1966
Enzymatic activity of DPIV/CD26 is involved in PMA-induced hyperphosphorylation of p56lck.
    Immunology letters, 1995, Volume: 46, Issue:1-2

    Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; src-Family Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles

1995
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells.
    Immunobiology, 1994, Volume: 192, Issue:1-2

    Topics: Blotting, Western; Cell Division; Cytokines; Dipeptidyl Peptidase 4; DNA; DNA Replication; Humans; Isoelectric Focusing; Lymphoma, Large B-Cell, Diffuse; Lysine; Piperidines; Thiazoles; Tumor Cells, Cultured

1994
Inhibition of gentamicin uptake into cultured mouse proximal tubule epithelial cells by L-lysine.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:1

    Topics: Animals; Cell Line; Coloring Agents; Culture Media; Epithelium; Gentamicins; Kidney Tubules, Proximal; Lysine; Mice; Mice, Transgenic; Models, Biological; Tetrazolium Salts; Thiazoles

1993
A single mutation in the M-subunit of Rhodospirillum rubrum confers herbicide resistance.
    FEBS letters, 1997, Jun-16, Volume: 409, Issue:3

    Topics: Drug Resistance, Microbial; Electron Spin Resonance Spectroscopy; Glutamic Acid; Herbicides; Lysine; Mutation; Photosynthetic Reaction Center Complex Proteins; Rhodospirillum rubrum; Thiazoles

1997
Suppression of arthritis by the inhibitors of dipeptidyl peptidase IV.
    International journal of immunopharmacology, 1997, Volume: 19, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; Boronic Acids; Cells, Cultured; Collagen; Diamines; Dipeptides; Dipeptidyl Peptidase 4; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Hydroxylamines; Immunosuppressive Agents; Lymphocyte Activation; Lysine; Models, Immunological; Rats; Rats, Inbred F344; Rats, Inbred Lew; Serine Proteinase Inhibitors; T-Lymphocytes; Thiazoles

1997
Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-beta 1 (TGF-beta 1) in stimulated mouse splenocytes and thymocytes.
    Immunology letters, 1997, Volume: 58, Issue:1

    Topics: Animals; Cell Division; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Interleukins; Lysine; Mice; Mice, Inbred BALB C; Protease Inhibitors; Pyrrolidines; Spleen; Thiazoles; Thymus Gland; Transforming Growth Factor beta

1997
Dipeptidyl peptidase IV (DP IV, CD26) is involved in regulation of DNA synthesis in human keratinocytes.
    FEBS letters, 1998, May-22, Volume: 428, Issue:1-2

    Topics: Adult; Dipeptidyl Peptidase 4; DNA; Gene Expression; Humans; Keratinocytes; Lysine; Polymerase Chain Reaction; Protease Inhibitors; Pyrrolidines; Thiazoles

1998
Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones.
    Journal of neuroimmunology, 1998, Jul-01, Volume: 87, Issue:1-2

    Topics: CD4 Antigens; Clone Cells; Cytokines; Dipeptidyl Peptidase 4; DNA; Humans; Lysine; Multiple Sclerosis; Myelin Basic Protein; Protease Inhibitors; Pyrrolidines; T-Lymphocytes; Thiazoles

1998
Inhibition of herpes simplex virus replication by a 2-amino thiazole via interactions with the helicase component of the UL5-UL8-UL52 complex.
    Journal of virology, 1998, Volume: 72, Issue:9

    Topics: Amino Acid Sequence; Animals; Antiviral Agents; Asparagine; Base Composition; Cell Line; Chlorocebus aethiops; DNA Helicases; DNA Primase; DNA Replication; Drug Resistance, Microbial; Enzyme Inhibitors; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Lysine; Molecular Sequence Data; Mutagenesis; Sequence Homology, Amino Acid; Spodoptera; Thiazoles; Vero Cells; Viral Proteins; Virus Replication

1998
Use of 99mTc-mercaptoacetyltriglycine (MAG3)-biocytin hepatobiliary scintigraphy to study the protective effect of a synthetic enzyme inhibitor on acute hepatotoxicity in mice.
    Nuclear medicine and biology, 1998, Volume: 25, Issue:6

    Topics: Animals; Biliary Tract; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Liver; Liver Diseases; Lysine; Mice; Mice, Inbred BALB C; Necrosis; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Thiazoles

1998
Early phosphorylation events induced by DPIV/CD26-specific inhibitors.
    Cellular immunology, 1998, Oct-10, Volume: 189, Issue:1

    Topics: Calcium; CD3 Complex; Cyclic AMP; Dipeptidyl Peptidase 4; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Mitogens; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tyrosine

1998
Specific inhibitors of dipeptidyl peptidase IV suppress mRNA expression of DP IV/CD26 and cytokines.
    Advances in experimental medicine and biology, 2000, Volume: 477

    Topics: Autocrine Communication; Dipeptidyl Peptidase 4; Enzyme Induction; Feedback; G1 Phase; Humans; Interferon-gamma; Interleukin-12; Interleukin-2; Lymphocyte Activation; Lysine; Pokeweed Mitogens; RNA, Messenger; Serine Proteinase Inhibitors; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1

2000
Dipeptidyl peptidase IV in inflammatory CNS disease.
    Advances in experimental medicine and biology, 2000, Volume: 477

    Topics: Animals; Animals, Outbred Strains; Autoimmune Diseases; Dipeptidyl Peptidase 4; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Lymphocyte Activation; Lysine; Mice; Multiple Sclerosis; Myelin Basic Protein; Pyrrolidines; Rats; Serine Proteinase Inhibitors; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Thiazoles

2000
Dipeptidyl peptidase IV (CD26): role in T cell activation and autoimmune disease.
    Advances in experimental medicine and biology, 2000, Volume: 477

    Topics: Autoimmune Diseases; CD4-Positive T-Lymphocytes; Dipeptidyl Peptidase 4; DNA Replication; Flow Cytometry; Humans; Immunodominant Epitopes; Lymphocyte Activation; Lymphokines; Lysine; Multiple Sclerosis; Myelin Basic Protein; Phytohemagglutinins; Pyrrolidines; Serine Proteinase Inhibitors; Thiazoles

2000
DNA synthesis in cultured human keratinocytes and HaCaT keratinocytes is reduced by specific inhibition of dipeptidyl peptidase IV (CD26) enzymatic activity.
    Advances in experimental medicine and biology, 2000, Volume: 477

    Topics: Adult; Cell Line; Cells, Cultured; Dipeptidyl Peptidase 4; DNA Replication; Enzyme Induction; Flow Cytometry; Humans; Infant, Newborn; Keratinocytes; Lysine; Male; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Proteinase Inhibitors; Thiazoles

2000
Dipeptidyl peptidase IV (DP IV/CD26) mRNA expression in PWM-stimulated T-cells is suppressed by specific DP IV inhibition, an effect mediated by TGF-beta(1).
    Biochemical and biophysical research communications, 2000, Aug-02, Volume: 274, Issue:2

    Topics: Antibodies; Cells, Cultured; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Humans; Interferon-gamma; Interleukin-2; Lysine; Pokeweed Mitogens; Protease Inhibitors; RNA, Messenger; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta

2000
N-phenacylthiazolium bromide decreases renal and increases urinary advanced glycation end products excretion without ameliorating diabetic nephropathy in C57BL/6 mice.
    Diabetes, obesity & metabolism, 2001, Volume: 3, Issue:4

    Topics: Animals; Arginine; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glycation End Products, Advanced; Kidney; Kidney Glomerulus; Lysine; Mice; Mice, Inbred C57BL; Proteinuria; Thiazoles

2001
Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2-(4-aminophenyl)benzothiazole amino acid prodrugs.
    Journal of medicinal chemistry, 2002, Jan-31, Volume: 45, Issue:3

    Topics: Alanine; Antineoplastic Agents; Drug Stability; Hydrogen-Ion Concentration; Lysine; Prodrugs; Solubility; Structure-Activity Relationship; Thiazoles

2002
Covalent bonding of lysine to EVAL membrane surface to improve survival of cultured cerebellar granule neurons.
    Biomaterials, 2003, Volume: 24, Issue:8

    Topics: Animals; Biocompatible Materials; Cell Survival; Cells, Cultured; Cerebellum; L-Lactate Dehydrogenase; Lysine; Materials Testing; Membranes, Artificial; Microscopy, Electron, Scanning; Neurons; Polyvinyls; Rats; Surface Properties; Tetrazolium Salts; Thiazoles

2003
Coupling of contact sensitizers to thiol groups is a key event for the activation of monocytes and monocyte-derived dendritic cells.
    The Journal of investigative dermatology, 2003, Volume: 120, Issue:2

    Topics: Acetates; Anti-Infective Agents; Antioxidants; Cysteine; Dendritic Cells; Ethylmaleimide; Humans; Interleukin-1; Lysine; Maleimides; MAP Kinase Signaling System; Monocytes; Phosphorylation; Picryl Chloride; Succinimides; Sulfhydryl Compounds; Sulfhydryl Reagents; Thiazoles; Tyrosine

2003
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:12

    Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine

2003
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: alpha-Synuclein; Anaerobiosis; Benzothiazoles; Circular Dichroism; Escherichia coli; Flavanones; Flavonoids; Humans; Light; Lysine; Microscopy, Atomic Force; Molecular Weight; Nerve Tissue Proteins; Oxidation-Reduction; Protein Conformation; Quinones; Scattering, Radiation; Solubility; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Synucleins; Thiazoles; Tyrosine

2004
Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectromet
    Chemical research in toxicology, 2004, Volume: 17, Issue:9

    Topics: Binding Sites; Carbon Isotopes; Chemistry Techniques, Analytical; DNA Adducts; Glutathione; Histidine; Humans; In Vitro Techniques; Lysine; Magnetic Resonance Spectroscopy; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiazoles

2004
Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin.
    Biochemistry, 2005, Mar-22, Volume: 44, Issue:11

    Topics: Amyloid; Benzothiazoles; beta 2-Microglobulin; Binding Sites; Chromatography, Gel; Congo Red; Deuterium Exchange Measurement; Electrophoresis, Capillary; Fluorescent Dyes; Humans; Hydrolysis; Lysine; Microscopy, Atomic Force; Protein Conformation; Protein Folding; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Temperature; Thiazoles; Time Factors

2005
Controlling {beta}-amyloid oligomerization by the use of naphthalene sulfonates: trapping low molecular weight oligomeric species.
    The Journal of biological chemistry, 2005, Oct-14, Volume: 280, Issue:41

    Topics: Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Animals; Anions; Benzothiazoles; Biochemistry; Cell Line; Chromatography; Congo Red; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Hydrogen-Ion Concentration; Kinetics; Light; Lysine; Magnetic Resonance Spectroscopy; Mice; Micelles; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Weight; Naphthalenesulfonates; Peptide Fragments; Peptides; Phenylalanine; Prions; Protein Structure, Secondary; Scattering, Radiation; Sodium Dodecyl Sulfate; Spectrophotometry; Static Electricity; Sulfonic Acids; Temperature; Tetrazolium Salts; Thiazoles; Time Factors

2005
Potential irritation of lysine derivative surfactants by hemolysis and HaCaT cell viability.
    Toxicology letters, 2006, Feb-08, Volume: 161, Issue:1

    Topics: Betaine; Cell Line; Cell Survival; Cetrimonium; Cetrimonium Compounds; Colorimetry; Erythrocytes; Hemolysis; Humans; Inhibitory Concentration 50; Irritants; Lysine; Molecular Structure; Neutral Red; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles

2006
Inhibitory effect of a mixture containing ascorbic acid, lysine, proline and green tea extract on critical parameters in angiogenesis.
    Oncology reports, 2005, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Extracellular Matrix; Fibroblast Growth Factor 2; Formaldehyde; Humans; Immunohistochemistry; In Vitro Techniques; Laminin; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Osteosarcoma; Plant Extracts; Platelet-Derived Growth Factor; Proline; Proteoglycans; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A

2005
Compartmental pharmacokinetics and tissue distribution of the antifungal triazole ravuconazole following intravenous administration of its di-lysine phosphoester prodrug (BMS-379224) in rabbits.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:5

    Topics: Adipose Tissue; Animals; Brain; Half-Life; Injections, Intravenous; Kidney; Liver; Lung; Lysine; Prodrugs; Rabbits; Thiazoles; Tissue Distribution; Triazoles

2005
Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, May-03, Volume: 26, Issue:18

    Topics: Animals; Animals, Newborn; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Cyclic GMP; Cyclic N-Oxides; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Fluorescent Antibody Technique; Free Radical Scavengers; Gene Expression; Glial Fibrillary Acidic Protein; HIV Envelope Protein gp120; Imidazoles; Lipopolysaccharides; Lysine; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Thionucleotides; Time Factors

2006
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function.
    Journal of leukocyte biology, 2006, Volume: 80, Issue:3

    Topics: Adenosine Deaminase; Dipeptidyl Peptidase 4; Enzyme Activation; Gene Expression Profiling; Glycoproteins; Humans; Leukocytes, Mononuclear; Lysine; Membrane Proteins; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Structure-Activity Relationship; Thiazoles

2006
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
    American journal of nephrology, 2006, Volume: 26, Issue:5

    Topics: Animals; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Lysine; Mice; Mice, Mutant Strains; Thiazoles

2006
Determination of interleukin-1alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants.
    Toxicology letters, 2006, Nov-01, Volume: 167, Issue:1

    Topics: Cell Line; Cell Survival; Cytokines; Humans; Interleukin-1alpha; Irritants; Keratinocytes; Lysine; Sodium Dodecyl Sulfate; Surface-Active Agents; Tetrazolium Salts; Thiazoles

2006
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?
    Endocrinology, 2007, Volume: 148, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cytosol; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Glycation End Products, Advanced; Kidney; Lysine; Male; Mitochondria; NF-kappa B; Oxidative Stress; Protein Kinase C; Ramipril; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin-Angiotensin System; Superoxide Dismutase; Thiazoles; Vascular Endothelial Growth Factor A

2007
Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation.
    International immunopharmacology, 2006, Dec-20, Volume: 6, Issue:13-14

    Topics: Animals; Antibodies; CD13 Antigens; Cell Proliferation; Dipeptidyl-Peptidase IV Inhibitors; Drug Synergism; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Hydroxamic Acids; Immunosuppressive Agents; Leukocytes, Mononuclear; Lymphocyte Activation; Lysine; Mice; Mice, Inbred Strains; Myelin Proteolipid Protein; Peptide Fragments; Phytohemagglutinins; Pokeweed Mitogens; Protease Inhibitors; Pyrrolidines; T-Lymphocytes; Thiazoles; Transforming Growth Factor beta1; Vaccination

2006
Surface tailoring of poly(ethylene terephthalate) via ligand-tethered comb-like PEG to enhance endothelialization.
    Journal of materials science. Materials in medicine, 2008, Volume: 19, Issue:1

    Topics: Aldehydes; Cell Adhesion; Cell Proliferation; Cell Survival; Endothelial Cells; Endothelium; Humans; Ligands; Lysine; Platelet Adhesiveness; Polyethylene Glycols; Polyethylene Terephthalates; Surface Properties; Tetrazolium Salts; Thiazoles; Umbilical Veins

2008
Inhibitors of dipeptidyl peptidase IV-like activity mediate antifibrotic effects in normal and keloid-derived skin fibroblasts.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:4

    Topics: Actins; Animals; Collagen Type I; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Keloid; Lysine; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrrolidines; Skin; Thiazoles; Transforming Growth Factor beta1

2008
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
    Diabetologia, 2008, Volume: 51, Issue:6

    Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan

2008
Preparation and gene delivery of alkaline amino acids-based cationic liposomes.
    Archives of pharmacal research, 2008, Volume: 31, Issue:7

    Topics: Amino Acids; Arginine; Cations; Cell Line; Cholesterol; Deoxyribonuclease I; Drug Carriers; Electrophoresis, Agar Gel; Gene Transfer Techniques; Genes, Reporter; Histidine; Humans; Light; Liposomes; Luciferases; Lysine; Microscopy, Electron, Transmission; Scattering, Radiation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Transfection

2008
Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines.
    Circulation, 2008, Sep-02, Volume: 118, Issue:10

    Topics: Aging; Animals; Aorta; Collagen; Dogs; Drug Evaluation, Preclinical; Elastin; Glycation End Products, Advanced; Heart Ventricles; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles; Vasa Vasorum; Vascular Resistance; Ventricular Function, Left

2008
Advanced glycation end products increase transglutaminase activity in primary porcine tenocytes.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2009, Volume: 57, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Lysine; RNA, Messenger; Stifle; Swine; Tendons; Tetrazolium Salts; Thiazoles; Transglutaminases

2009
Letter by Hartog et al. regarding article, "Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines".
    Circulation, 2009, Mar-17, Volume: 119, Issue:10

    Topics: Animals; Arginine; Collagen; Cross-Linking Reagents; Dogs; Glycation End Products, Advanced; Hypertension; Lysine; Muscle, Smooth, Vascular; Thiazoles

2009
Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.
    Biochemistry, 2009, Jul-07, Volume: 48, Issue:26

    Topics: Amyloid; Amyloid beta-Peptides; Amyloid Neuropathies, Familial; Aspartic Acid; Benzothiazoles; Glutamic Acid; Humans; Kinetics; Leucine; Lysine; Microscopy, Electron, Transmission; Models, Molecular; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phenylalanine; Protein Structure, Secondary; Spectrometry, Fluorescence; Thiazoles; X-Ray Diffraction

2009
Role of dipeptidyl peptidase IV (DP IV)-like enzymes in T lymphocyte activation: investigations in DP IV/CD26-knockout mice.
    Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:3

    Topics: Animals; Cell Proliferation; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Disease Models, Animal; DNA; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrrolidines; Spleen; T-Lymphocytes; Thiazoles

2009
FRET quenching of photosensitizer singlet oxygen generation.
    The journal of physical chemistry. B, 2009, Mar-12, Volume: 113, Issue:10

    Topics: Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Radiation; Fluorescence Resonance Energy Transfer; Humans; Lysine; Models, Chemical; Oxygen; Photochemistry; Photosensitizing Agents; Protein Structure, Tertiary; Singlet Oxygen; Tetrazolium Salts; Thiazoles; Time Factors

2009
Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions.
    Immunobiology, 2011, Volume: 216, Issue:12

    Topics: Animals; CD13 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Chemokine CXCL12; Chemotaxis; Dipeptidyl Peptidase 4; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Humans; Hydroxamic Acids; Lymphocyte Activation; Lysine; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Pyrroles; Pyrrolidines; Thiazoles; Transgenes

2011
Durable molecular response despite F317L and E255K mutations: Successful treatment of chronic myeloid leukemia with sequential imatinib, nilotinib and dasatinib.
    Leukemia research, 2012, Volume: 36, Issue:1

    Topics: Adult; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Pharmacological; Biomarkers, Tumor; Dasatinib; Female; Fusion Proteins, bcr-abl; Glutamic Acid; Humans; Imatinib Mesylate; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lysine; Mutation, Missense; Phenylalanine; Piperazines; Polymorphism, Single Nucleotide; Pyrimidines; Remission Induction; Thiazoles; Time Factors; Treatment Outcome

2012
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.
    Biochimica et biophysica acta, 2012, Volume: 1818, Issue:9

    Topics: Alzheimer Disease; Amino Acid Sequence; Benzothiazoles; Biophysics; Circular Dichroism; Humans; Lipid Bilayers; Lipids; Liposomes; Lysine; Magnetic Resonance Spectroscopy; Methylation; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity; tau Proteins; Thiazoles; Unilamellar Liposomes

2012
In vitro exposure of precision-cut lung slices to 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole lysylamide dihydrochloride (NSC 710305, Phortress) increases inflammatory cytokine content and tissue damage.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 131, Issue:2

    Topics: Animals; Cytokines; In Vitro Techniques; Inflammation Mediators; Lung; Lysine; Male; Rats; Rats, Inbred F344; Thiazoles

2013
Molecular mechanism of tau aggregation induced by anionic and cationic dyes.
    Journal of Alzheimer's disease : JAD, 2013, Volume: 35, Issue:2

    Topics: Anions; Benzothiazoles; Cations; Cell Line; Coloring Agents; Congo Red; Electrochemistry; Flow Cytometry; Humans; Immunohistochemistry; Lysine; Methylene Blue; Microscopy, Electron; Models, Molecular; Organic Chemicals; Protein Binding; Protein Structure, Secondary; Solubility; tau Proteins; Thermodynamics; Thiazoles

2013
N-Epsilon-(carboxymethyl)lysine is unable to induce endothelial dysfunction but is able to attenuate Ages-induced endothelium damage in human umbilical vein endothelial cells.
    Die Pharmazie, 2013, Volume: 68, Issue:4

    Topics: Acridine Orange; Adult; Algorithms; Apoptosis; Data Interpretation, Statistical; Endothelial Cells; Endothelium, Vascular; Ethidium; Female; Fluorescence Polarization; Glycation End Products, Advanced; Humans; Intercellular Adhesion Molecule-1; Lysine; Pregnancy; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1; Umbilical Veins

2013
Preparation of eutectic substrate mixtures for enzymatic conversion of ATC to L-cysteine at high concentration levels.
    Bioprocess and biosystems engineering, 2014, Volume: 37, Issue:6

    Topics: Lysine; Manganese Compounds; Models, Chemical; Rhizobiaceae; Sodium Hydroxide; Sorbitol; Sulfates; Thiazoles

2014
In vitro glycation of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules.
    Biomaterials, 2015, Volume: 51

    Topics: Animals; Capillaries; Cattle; Cell Differentiation; Cells, Cultured; Collagen; Cytoskeleton; Dermis; Endothelial Cells; Fibroblasts; Filaggrin Proteins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Lysine; Mice; Neurons; Protective Agents; Skin; Thiazoles; Tissue Engineering

2015
Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells.
    Molecular neurobiology, 2016, Volume: 53, Issue:6

    Topics: Anacardic Acids; Anilides; Benzamides; Cell Line, Tumor; Chromatin Immunoprecipitation; Deoxyadenosines; Epigenesis, Genetic; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Group IV Phospholipases A2; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; L-Lactate Dehydrogenase; Lysine; Neuroblastoma; Pyridines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thionucleosides; Valproic Acid

2016
A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Acetamides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Humans; Lysine; Models, Molecular; Molecular Structure; Sirtuin 2; Structure-Activity Relationship; Substrate Specificity; Suramin; Thiazoles

2016
In situ chemical behaviour of methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) in reconstructed human epidermis: a new approach to the cross-reactivity issue.
    Contact dermatitis, 2016, Volume: 74, Issue:3

    Topics: Cross Reactions; Cysteine; Epidermis; Histidine; Humans; Lysine; Magnetic Resonance Spectroscopy; Sulfhydryl Compounds; Thiazoles

2016
Acetylation of lysine residues in apomyoglobin: Structural changes, amyloid fibrillation, and role of surface charge.
    International journal of biological macromolecules, 2018, Volume: 107, Issue:Pt A

    Topics: Acetylation; Amyloidogenic Proteins; Animals; Apoproteins; Benzothiazoles; Cell Survival; Heme; Horses; Lysine; Myoglobin; PC12 Cells; Protein Aggregates; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Spectrometry, Fluorescence; Static Electricity; Thiazoles

2018