Page last updated: 2024-08-21

thiazoles and lusutrombopag

thiazoles has been researched along with lusutrombopag in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (46.67)24.3611
2020's16 (53.33)2.80

Authors

AuthorsStudies
Kim, ES1
Ishibashi, T; Kano, T; Katsube, T; Wajima, T1
Abe, S; Kamimura, K; Kawai, H; Sakamaki, A; Takamura, M; Terai, S; Tsuchiya, A; Watanabe, T; Yamagiwa, S1
Ishimura, N; Isoda, K; Kataoka, M; Kinoshita, Y; Miyake, T; Sato, S; Tobita, H; Yazaki, T1
Abe, K; Fujita, M; Hayashi, M; Ohira, H; Okai, K; Takahashi, A1
Dohi, K; Gahara, Y; Hasegawa, M; Kitaura, M; Kurino-Yamada, T; Kuwabara, K; Nogami, W; Oshima, I; Sugiyama, K; Takahashi, K; Yamada, H; Yoshida, H1
Fukuhara, T; Imawari, M; Izumi, N; Kano, T; Katsube, T; Kawazoe, S; Kudo, M; Kurokawa, M; Ochiai, T; Osaki, Y; Seike, M; Tamai, H; Tanaka, K; Tateishi, R; Yamamoto, K1
Katano, T; Mizuta, K; Okada, N; Sanada, Y1
Abiru, S; Fukuhara, T; Hidaka, H; Igura, T; Imawari, M; Ishikawa, T; Izumi, N; Kano, T; Katsube, T; Kimura, K; Kudo, M; Kurokawa, M; Kurosaki, M; Nagata, T; Ochiai, T; Osaki, Y; Seike, M; Tanaka, H; Tanaka, K; Yamamoto, K1
Enomoto, N; Higuchi, M; Itakura, J; Izumi, N; Komiyama, Y; Kubota, Y; Kurosaki, M; Nakanishi, H; Okada, M; Shimizu, T; Takada, H; Takahashi, Y; Takaura, K; Tamaki, N; Tsuchiya, K; Wang, W; Watakabe, K; Yasui, Y1
Fukuhara, T; Kano, T; Katsube, T; Shimizu, R; Wajima, T1
Al-Horani, RA; Clemons Bankston, P1
Fukuhara, T; Kano, T; Katsube, T; Wajima, T1
Hussar, DA1
Akahane, T; Fujinaga, Y; Ishida, K; Kaji, K; Kawaratani, H; Kaya, D; Kubo, T; Moriya, K; Namisaki, T; Sawada, Y; Shimozato, N; Takaya, H; Tsuji, Y; Yoshiji, H1
Alkhouri, N; Bentley, R; Imawari, M; Izumi, N; Kano, T; Ochiai, T; Osaki, Y; Trevisani, F1
Flamm, SL; Nilles, KM1
Arase, Y; Atsukawa, M; Hidaka, H; Horie, R; Itokawa, N; Iwakiri, K; Iwasaki, S; Kagawa, T; Kako, M; Koizumi, W; Miyazaki, K; Okina, S; Satoh, T; Shao, X; Suzuki, T; Takiguchi, H; Uojima, H; Wada, N1
Asama, H; Fukushima, T; Kawano, K; Kobayashi, S; Maeda, S; Morimoto, M; Nagashima, S; Ohkawa, S; Sano, Y; Tanaka, S; Ueno, M1
Al, M; Armstrong, N; Buksnys, T; Büyükkaramikli, N; Drachen, T; Duffy, S; Huertas Carrera, V; Kleijnen, J; Penton, H; Raatz, H; Riemsma, R; Ryder, S; Shah, D; Swift, S; Wetzelaer, P; Worthy, G1
Kanazu, T; Katsube, T; Kawachi, T; Ninomiya, M; Wajima, T1
Isoda, N; Koyashiki, Y; Kurata, H; Maeda, H; Miura, K; Morimoto, N; Nomoto, H; Numao, N; Sasaki, T; Takaoka, Y; Watanabe, S; Yamamoto, H1
Ishibashi, K; Kaneko, T; Takano, Y1
Afdhal, N; Bentley, R; Giannini, EG; Kano, T; Ochiai, T; Shrestha, P1
Katsube, T; Shimizu, R; Wajima, T1
Buscarini, E; Dinis-Ribeiro, M; Fuccio, L; Hassan, C; Radaelli, F1
Bubalo, J; Gilreath, J; Lo, M1
Fujiwara, M; Hiroi, S; Hongo, Y; Igarashi, A; Iwasaki, K; Kitanishi, Y; Takeshima, T; Tateishi, R; Yoshida, M1
Arai, T; Arase, Y; Atsukawa, M; Furuichi, Y; Hidaka, H; Itoi, T; Kako, M; Takeuchi, H; Uojima, H1
Biolato, M; Grieco, A; Marrone, G; Miele, L; Vitale, F1

Reviews

5 review(s) available for thiazoles and lusutrombopag

ArticleYear
New Small Molecule Drugs for Thrombocytopenia: Chemical, Pharmacological, and Therapeutic Use Considerations.
    International journal of molecular sciences, 2019, Jun-20, Volume: 20, Issue:12

    Topics: Aminopyridines; Animals; Cinnamates; Drug Development; Humans; Morpholines; Oxazines; Pyridines; Pyrimidines; Receptors, Thrombopoietin; Small Molecule Libraries; Syk Kinase; Thiazoles; Thiophenes; Thrombocytopenia

2019
Lusutrombopag Is Safe and Efficacious for Treatment of Thrombocytopenia in Patients With and Without Hepatocellular Carcinoma.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2020, Volume: 18, Issue:11

    Topics: Carcinoma, Hepatocellular; Cinnamates; Humans; Liver Neoplasms; Thiazoles; Thrombocytopenia

2020
Thrombocytopenia in Chronic Liver Disease: New Management Strategies.
    Clinics in liver disease, 2020, Volume: 24, Issue:3

    Topics: Chronic Disease; Cinnamates; Hemorrhage; Humans; Liver Diseases; Platelet Count; Platelet Transfusion; Receptors, Thrombopoietin; Risk Factors; Surgical Procedures, Operative; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoiesis

2020
Avatrombopag and lusutrombopag for thrombocytopenia in people with chronic liver disease needing an elective procedure: a systematic review and cost-effectiveness analysis.
    Health technology assessment (Winchester, England), 2020, Volume: 24, Issue:51

    Topics: Bayes Theorem; Cinnamates; Clinical Trials as Topic; Cost-Benefit Analysis; End Stage Liver Disease; Humans; Models, Economic; Platelet Transfusion; Quality-Adjusted Life Years; Receptors, Thrombopoietin; Secondary Care; Technology Assessment, Biomedical; Thiazoles; Thiophenes; Thrombocytopenia

2020
Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists.
    Drugs, 2021, Volume: 81, Issue:11

    Topics: Benzoates; Cinnamates; Dose-Response Relationship, Drug; Drug Monitoring; Health Knowledge, Attitudes, Practice; Humans; Hydrazines; Pharmacists; Platelet Count; Pyrazoles; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Thiazoles; Thiophenes; Thrombocytopenia; Thrombopoietin

2021

Trials

6 trial(s) available for thiazoles and lusutrombopag

ArticleYear
Population Pharmacokinetic and Pharmacodynamic Modeling of Lusutrombopag, a Newly Developed Oral Thrombopoietin Receptor Agonist, in Healthy Subjects.
    Clinical pharmacokinetics, 2016, Volume: 55, Issue:11

    Topics: Adult; Age Factors; Area Under Curve; Body Weight; Cinnamates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Racial Groups; Receptors, Thrombopoietin; Sex Factors; Thiazoles; White People

2016
A randomized controlled trial of lusutrombopag in Japanese patients with chronic liver disease undergoing radiofrequency ablation.
    Journal of gastroenterology, 2019, Volume: 54, Issue:2

    Topics: Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chronic Disease; Cinnamates; Double-Blind Method; Female; Half-Life; Humans; Japan; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Platelet Count; Platelet Transfusion; Preoperative Care; Radiofrequency Ablation; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Thrombosis

2019
Lusutrombopag Reduces Need for Platelet Transfusion in Patients With Thrombocytopenia Undergoing Invasive Procedures.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:6

    Topics: Aged; Catheter Ablation; Cinnamates; Double-Blind Method; Female; Follow-Up Studies; Humans; Incidence; Japan; Liver Cirrhosis; Male; Platelet Transfusion; Postoperative Hemorrhage; Retrospective Studies; Thiazoles; Thrombocytopenia; Treatment Outcome

2019
Effects of Food and Calcium Carbonate on the Pharmacokinetics of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist.
    Clinical therapeutics, 2019, Volume: 41, Issue:9

    Topics: Administration, Oral; Adult; Aged; Biological Availability; Calcium Carbonate; Cinnamates; Cross-Over Studies; Fasting; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Receptors, Thrombopoietin; Tablets; Thiazoles; Young Adult

2019
Effectiveness of Lusutrombopag in Patients with Mild to Moderate Thrombocytopenia.
    Digestive diseases (Basel, Switzerland), 2020, Volume: 38, Issue:4

    Topics: Aged; Cinnamates; Female; Humans; Male; Platelet Count; Postoperative Complications; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Time Factors; Treatment Outcome

2020
Impact of Anti-GPIIb/IIIa Antibody-Producing B Cells as a Predictor of the Response to Lusutrombopag in Thrombocytopenic Patients with Liver Disease.
    Digestive diseases (Basel, Switzerland), 2021, Volume: 39, Issue:3

    Topics: Aged; Aged, 80 and over; Autoantibodies; B-Lymphocytes; Blood Platelets; Cinnamates; Female; Humans; Liver Diseases; Male; Middle Aged; Multivariate Analysis; Organ Size; Platelet Count; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Spleen; Thiazoles; Thrombocytopenia

2021

Other Studies

19 other study(ies) available for thiazoles and lusutrombopag

ArticleYear
Lusutrombopag: First Global Approval.
    Drugs, 2016, Volume: 76, Issue:1

    Topics: Cinnamates; Drug Approval; Humans; Japan; Liver Diseases; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia

2016
Lusutrombopag increases hematocytes in a compensated liver cirrhosis patient.
    Clinical journal of gastroenterology, 2017, Volume: 10, Issue:3

    Topics: Carcinoma, Hepatocellular; Cinnamates; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Thiazoles; Thrombocytopenia

2017
Efficacy of Repeated Lusutrombopag Administration for Thrombocytopenia in a Patient Scheduled for Invasive Hepatocellular Carcinoma Treatment.
    Internal medicine (Tokyo, Japan), 2017, Nov-01, Volume: 56, Issue:21

    Topics: Carcinoma, Hepatocellular; Chronic Disease; Cinnamates; Female; Humans; Liver Diseases; Liver Neoplasms; Middle Aged; Platelet Count; Thiazoles; Thrombocytopenia

2017
Two cases of liver cirrhosis treated with lusutrombopag before partial splenic embolization.
    Fukushima journal of medical science, 2017, Dec-19, Volume: 63, Issue:3

    Topics: Adult; Cinnamates; Embolization, Therapeutic; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Thiazoles

2017
Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.
    Experimental hematology, 2018, Volume: 59

    Topics: Animals; Blood Platelets; Cell Line; Cell Proliferation; Cinnamates; Drug Evaluation, Preclinical; Gene Knock-In Techniques; Humans; Megakaryocytes; Mice; Mice, Transgenic; Models, Biological; Receptors, Thrombopoietin; Thiazoles

2018
Lusutrombopag as pretreatment for liver biopsy following liver transplantation.
    Pediatrics international : official journal of the Japan Pediatric Society, 2018, Volume: 60, Issue:11

    Topics: Adolescent; Biopsy; Cinnamates; Humans; Liver; Liver Transplantation; Living Donors; Male; Platelet Count; Preoperative Care; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia

2018
Real-life experience of lusutrombopag for cirrhotic patients with low platelet counts being prepared for invasive procedures.
    PloS one, 2019, Volume: 14, Issue:2

    Topics: Aged; Carcinoma, Hepatocellular; Catheter Ablation; Chemoembolization, Therapeutic; Cinnamates; Esophageal and Gastric Varices; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Platelet Count; Platelet Transfusion; Receptors, Thrombopoietin; Retrospective Studies; Sclerotherapy; Thiazoles; Thrombocytopenia

2019
Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Blood Platelets; Chronic Disease; Cinnamates; Female; Humans; Liver Diseases; Male; Middle Aged; Models, Biological; Platelet Count; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia; Young Adult

2019
New Drugs 2019, part 4.
    Nursing, 2019, Volume: 49, Issue:11

    Topics: Aminopyridines; Cinnamates; Drug Approval; Factor Xa; Humans; Macrolides; Morpholines; Oligonucleotides; Oxazines; Pyridines; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Sisomicin; Tetracyclines; Thiazoles; Thiophenes; United States; United States Food and Drug Administration

2019
Repeated Lusutrombopag Treatment for Thrombocytopenia in Patients with Chronic Liver Disease.
    Digestion, 2021, Volume: 102, Issue:4

    Topics: Chronic Disease; Cinnamates; Humans; Liver Diseases; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia

2021
Human mass balance, metabolism, and cytochrome P450 phenotyping of lusutrombopag.
    Xenobiotica; the fate of foreign compounds in biological systems, 2021, Volume: 51, Issue:3

    Topics: Administration, Oral; Cinnamates; Cytochrome P-450 Enzyme System; Feces; Humans; Male; Oxidation-Reduction; Thiazoles

2021
Lusutrombopag is effective and safe in patients with chronic liver disease and severe thrombocytopenia: a multicenter retrospective study.
    BMC gastroenterology, 2020, Dec-14, Volume: 20, Issue:1

    Topics: Cinnamates; Humans; Liver Diseases; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia

2020
Lusutrombopag as a substitute for platelet transfusion for thrombocytopenia associated with chronic liver disease in a patient undergoing endoscopic spinal surgery: A case report.
    Medicine, 2021, Jan-15, Volume: 100, Issue:2

    Topics: Aged; Blood Loss, Surgical; Cinnamates; End Stage Liver Disease; Endoscopy; Female; Humans; Lumbar Vertebrae; Spinal Fractures; Thiazoles; Thrombocytopenia

2021
Bleeding events in lusutrombopag-treated thrombocytopenic patients.
    European journal of clinical investigation, 2021, Volume: 51, Issue:6

    Topics: Aged; Biopsy; Blood Loss, Surgical; Chemoembolization, Therapeutic; Chronic Disease; Cinnamates; Endoscopy, Digestive System; Female; Humans; Liver Diseases; Male; Middle Aged; Perioperative Care; Platelet Transfusion; Postoperative Hemorrhage; Radiofrequency Ablation; Randomized Controlled Trials as Topic; Receptors, Thrombopoietin; Retrospective Studies; Thiazoles; Thrombocytopenia; Tooth Extraction

2021
Quantitative systems pharmacology model of thrombopoiesis and platelet life-cycle, and its application to thrombocytopenia based on chronic liver disease.
    CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:5

    Topics: Blood Platelets; Cinnamates; Computer Simulation; End Stage Liver Disease; Humans; Receptors, Thrombopoietin; Thiazoles; Thrombopoiesis

2021
Second-generation thrombopoietin receptor agonists: New players in the management of cirrhotic patients undergoing therapeutic endoscopy?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2021, Volume: 53, Issue:10

    Topics: Cinnamates; Endoscopy; Humans; Liver Cirrhosis; Receptors, Thrombopoietin; Surveys and Questionnaires; Thiazoles; Thiophenes; Thrombocytopenia

2021
Effects of Lusutrombopag on Post-invasive Procedural Bleeding in Thrombocytopenic Patients with Chronic Liver Disease.
    Advances in therapy, 2022, Volume: 39, Issue:1

    Topics: Adolescent; Chronic Disease; Cinnamates; Humans; Liver Diseases; Receptors, Thrombopoietin; Thiazoles

2022
Lusutrombopag has slightly stronger effects on patients with mild thrombocytopenia compared with those with severe thrombocytopenia: A multicenter propensity score matching study.
    Journal of hepato-biliary-pancreatic sciences, 2022, Volume: 29, Issue:4

    Topics: Cinnamates; Humans; Propensity Score; Receptors, Thrombopoietin; Thiazoles; Thrombocytopenia

2022
A single course of lusutrombopag for multiple invasive procedures in cirrhosis-associated thrombocytopenia: A case series.
    Medicine, 2022, Nov-04, Volume: 101, Issue:44

    Topics: Cinnamates; Humans; Liver Cirrhosis; Thiazoles; Thrombocytopenia

2022